An internal support system for a stirred tank reactor includes at least one plate securable to one or more axial positions within a vessel of the stirred tank reactor along an impeller axis. The at least one plate has an outer portion at least partially defining a primary opening and a plurality of peripheral openings radially spaced from the primary opening. The at least one plate may further include an inner portion positioned within the primary opening and fixed to the outer portion, the inner portion being disposable about the impeller axis and at least partially defining a central opening sized to receive a rotatable impeller shaft therethrough. Each opening of the plurality of peripheral openings may be coaxial with a different port of a headplate of the stirred tank reactor when the at least one plate is secured to the axial position within the vessel.
An internal support system for a stirred tank reactor includes at least one plate securable to one or more axial positions within a vessel of the stirred tank reactor along an impeller axis. The at least one plate has an outer portion at least partially defining a primary opening and a plurality of peripheral openings radially spaced from the primary opening. The at least one plate may further include an inner portion positioned within the primary opening and fixed to the outer portion, the inner portion being disposable about the impeller axis and at least partially defining a central opening sized to receive a rotatable impeller shaft therethrough. Each opening of the plurality of peripheral openings may be coaxial with a different port of a headplate of the stirred tank reactor when the at least one plate is secured to the axial position within the vessel.
The disclosure relates to a truncated recombinant L1 protein of Human papillomavirus (HPV), a recombinant polynucleotide encoding the protein, a recombinant vector comprising the polynucleotide, an isolated cell comprising the recombinant vector, a composition comprising the protein, and a method for producing the protein. The disclosure also relates to an HPV virus-like particle (VLP) comprising the protein, an immunogenic composition comprising the protein or the VLP, and a method for inducing an immune response to HPV in an individual.
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p. ex. par les adjuvants chimiques
A61P 31/20 - Antiviraux pour le traitement des virus ADN
C12N 15/81 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour champignons pour levures
4.
TRUNCATED RECOMBINANT L1 PROTEIN OF HUMAN PAPILLOMAVIRUS
The disclosure relates to a truncated recombinant L1 protein of Human papillomavirus (HPV), a recombinant polynucleotide encoding the protein, a recombinant vector comprising the polynucleotide, an isolated cell comprising the recombinant vector, a composition comprising the protein, and a method for producing the protein. The disclosure also relates to an HPV virus-like particle (VLP) comprising the protein, an immunogenic composition comprising the protein or the VLP, and a method for inducing an immune response to HPV in an individual.
A scalable device includes a platform and a manifold removably coupled with the platform. The platform includes one or more first members, each having a first surface and one or more fins protruding from the first surface. The manifold includes an inlet, an outlet and one or more bases between the inlet and outlet for flowing through a fluid. Each base is formed with a plurality of first grooves on an interior side of the manifold and one or more second grooves on an exterior side of the manifold. Each respective base is removably fitted on a corresponding first member of the platform to enhance heat transfer between the platform and a fluid flowing through the manifold.
F28F 3/02 - Éléments ou leurs ensembles avec moyens pour augmenter la surface de transfert de chaleur, p. ex. avec des ailettes, avec des évidements, avec des ondulations
F28D 1/053 - Appareils échangeurs de chaleur comportant des ensembles de canalisations fixes pour une seule des sources de potentiel calorifique, les deux sources étant en contact chacune avec un côté de la paroi de la canalisation, dans lesquels l'autre source de potentiel calorifique est une grande masse de fluide, p. ex. radiateurs domestiques ou de moteur de voiture avec des canalisations d'échange de chaleur immergées dans la masse du fluide avec canalisations tubulaires les canalisations étant rectilignes
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Bioreactor system comprised of a bioreactor for cell
culturing, sensors, filters, and tubing attached to a rigid
panel for perfusion fermentation; bioreactor system
comprised of a bioreactor for cell culturing, sensors,
filters, and tubing attached to a rigid panel to
continuously process and test parameters and collect data on
a range of variables; bioreactor system comprised of a
bioreactor for cell culturing, sensors, filters, and tubing
attached to a rigid panel for continuous protein, molecule,
or cell line production using microbes; scientific apparatus
for the biomanufacturing, expression, purification and
collection of proteins and drug substances. Product development; product development in the fields of
protein manufacturing; research and development of
technology in the field of protein manufacturing; platform
as a service services (PaaS) featuring software for
designing and developing new products using protein
manufacturing; product research and development in the
biotechnology field.
A scalable device includes a platform and a manifold removably coupled with the platform. The platform includes one or more first members, each having a first surface and one or more fins protruding from the first surface. The manifold includes an inlet, an outlet and one or more bases between the inlet and outlet for flowing through a fluid. Each base is formed with a plurality of first grooves on an interior side of the manifold and one or more second grooves on an exterior side of the manifold. Each respective base is removably fitted on a corresponding first member of the platform to enhance heat transfer between the platform and a fluid flowing through the manifold.
F28F 3/06 - Éléments ou leurs ensembles avec moyens pour augmenter la surface de transfert de chaleur, p. ex. avec des ailettes, avec des évidements, avec des ondulations les moyens pouvant être fixés sur l'élément
F25B 21/00 - Machines, installations ou systèmes utilisant des effets électriques ou magnétiques
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes; scientific apparatus for the biomanufacturing, expression, purification and collection of proteins and drug substances. (1) Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; product research and development in the biotechnology field.
A structured assembly of perpendicular, interwoven fluidic conduits permits connections between conduits to be readily (and in some cases visibly) established, thereby providing operational convenience and amenability to automated means of validation or verification.
F16L 41/03 - Ensembles de branchements, p. ex. d'une seule pièce, soudés à l'autogène, rivetés comportant des pièces d'assemblage pour quatre tuyaux ou plus
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
F16K 11/072 - Soupapes ou clapets à voies multiples, p. ex. clapets mélangeursRaccords de tuyauteries comportant de tels clapets ou soupapesAménagement d'obturateurs et de voies d'écoulement spécialement conçu pour mélanger les fluides dont toutes les faces d'obturation se déplacent comme un tout comportant uniquement des tiroirs à éléments de fermeture articulés à pivot
F16K 27/00 - Structures des logementsMatériaux utilisés à cet effet
F16K 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
09 - Appareils et instruments scientifiques et électriques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Bioreactor system for perfusion fermentation; bioreactor
system to continuously process and test parameters and
collect data on a range of variables; bioreactor system for
continuous protein, molecule, or cell line production using
microbes. Manufacturing services for others in the field of
biotechnology. Product development; product development in the fields of
protein manufacturing; research and development of
technology in the field of protein manufacturing; platform
as a service services (PaaS) featuring software for
designing and developing new products using protein
manufacturing; research and development in the biotechnology
field.
09 - Appareils et instruments scientifiques et électriques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Bioreactor system for perfusion fermentation; bioreactor
system to continuously process and test parameters and
collect data on a range of variables; bioreactor system for
continuous protein, molecule, or cell line production using
microbes. Manufacturing services for others in the field of
biotechnology. Product development; product development in the fields of
protein manufacturing; research and development of
technology in the field of protein manufacturing; platform
as a service services (PaaS) featuring software for
designing and developing new products using protein
manufacturing; research and development in the biotechnology
field.
09 - Appareils et instruments scientifiques et électriques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Bioreactor system for perfusion fermentation; bioreactor
system to continuously process and test parameters and
collect data on a range of variables; bioreactor system for
continuous protein, molecule, or cell line production using
microbes. Manufacturing services for others in the field of
biotechnology. Product development; product development in the fields of
protein manufacturing; research and development of
technology in the field of protein manufacturing; platform
as a service services (PaaS) featuring software for
designing and developing new products using protein
manufacturing; research and development in the biotechnology
field.
09 - Appareils et instruments scientifiques et électriques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Bioreactor system for perfusion fermentation; bioreactor
system to continuously process and test parameters and
collect data on a range of variables; bioreactor system for
continuous protein, molecule, or cell line production using
microbes. Manufacturing services for others in the field of
biotechnology. Product development; product development in the fields of
protein manufacturing; research and development of
technology in the field of protein manufacturing; platform
as a service services (PaaS) featuring software for
designing and developing new products using protein
manufacturing; research and development in the biotechnology
field.
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes; scientific apparatus for the biomanufacturing, expression, purification and collection of proteins and drug substances. Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field.
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Product research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; product research and development in the biotechnology field; platform as a service services (PaaS) featuring software for designing and developing protein fermentation processes; platform as a service services (PaaS) featuring software for collecting, analyzing, and reporting data related to biotechnology and protein manufacturing.
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Product research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; product research and development in the biotechnology field; platform as a service services (PaaS) featuring software for designing and developing protein fermentation processes; platform as a service services (PaaS) featuring software for collecting, analyzing, and reporting data related to biotechnology and protein manufacturing.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Computer network server; computer network server for the secure electronic creation, transmission, storage, management, transfer, and retrieval of information related to biotechnology and protein manufacturing; network access server hardware; network access server hardware for the secure electronic creation, transmission, storage, management, transfer, and retrieval of information related to biotechnology and protein manufacturing.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Bioreactor system for perfusion fermentation; bioreactor
system to continuously process and test parameters and
collect data on a range of variables; bioreactor system for
continuous protein, molecule, or cell line production using
microbes.
09 - Appareils et instruments scientifiques et électriques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. (1) Manufacturing services for others in the field of biotechnology.
(2) Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.
09 - Appareils et instruments scientifiques et électriques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. (1) Manufacturing services for others in the field of biotechnology.
(2) Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.
09 - Appareils et instruments scientifiques et électriques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. (1) Manufacturing services for others in the field of biotechnology.
(2) Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.
09 - Appareils et instruments scientifiques et électriques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. (1) Manufacturing services for others in the field of biotechnology.
(2) Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.
09 - Appareils et instruments scientifiques et électriques
Produits et services
(1) Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes.
An aseptic connector includes first and second matable housings each comprising a plurality of connectors for fluid conduits. The fluid conduits enter the housings and may be force-fitted onto barbs or flanges on one side of the connectors, or may instead be molded directly onto the connectors. When the housings are joined, the opposite sides of the connectors mate to form fluid seals, thereby establishing fluid pathways between now-connected sets of tubes.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes, scientific apparatus for the biomanufacturing, expression, purification and collection of proteins and drug substances
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Manufacturing services for others in the field of biotechnology Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field
09 - Appareils et instruments scientifiques et électriques
Produits et services
Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbe
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Manufacturing services for others in the field of biotechnology Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Manufacturing services for others in the field of biotechnology Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Manufacturing services for others in the field of biotechnology Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field
09 - Appareils et instruments scientifiques et électriques
Produits et services
Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Manufacturing services for others in the field of biotechnology Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field
Described herein is a vessel cart including a base, a stand and a clamp. The base is configured to abut a lower portion of a vessel and hold the vessel upright when the vessel is loaded to the vessel card. The stand is connected to or formed with the base. The clamp is connected to the stand and configured to selectively grip an upper portion of the vessel. The clamp is also configured to open and close in a plane substantially parallel to a first surface of the base facing the clamp to allow the vessel to move laterally or radially relative to the clamp when the vessel is being loaded to the vessel cart or unloaded from the vessel cart.
B62B 3/10 - Voitures à bras ayant plus d'un essieu portant les roues servant au déplacementDispositifs de direction à cet effetAppareillage à cet effet caractérisées par des supports spécialement adaptés à des objets de forme définie
B62B 3/04 - Voitures à bras ayant plus d'un essieu portant les roues servant au déplacementDispositifs de direction à cet effetAppareillage à cet effet comportant des moyens pour accrocher ou saisir en place les objets à transporterAppareillage de manutention de charges
B62B 5/04 - Mécanismes de freinageDispositifs d'immobilisation
B62B 5/06 - Appareillage pour la propulsion à main, p. ex. guidons
Disclosed are systems and methods for alternately collecting a fluid in a plurality of containers without breaching its sterility. The system generally includes one or more collection modules, each having a valve and one or more container sets fluidically connected to the valve. Each container set includes first and second containers. The system also includes a control unit to control operation of the valve of each collection module to facilitate alternate collection of the fluid by the first and second containers of a container set. This may ensure that the fluid collected in one container is a true representative sample of the fluid collected in the container without compromising its sterile integrity.
A cell retention device includes a structured support with a plurality of circumferentially distributed ribs to retain the active filtering surface of a flexible, porous membrane filter medium. The filter medium surrounds the support in contact with the peaks of the ribs, thereby forming axial voids between the rib peaks. This arrangement imparts sufficient structural support over small regions of the filter medium to facilitate its use in a circular (or other rounded) configuration while providing sufficient channel volume to support high throughput of fluid sparse of cells.
B01D 69/02 - Membranes semi-perméables destinées aux procédés ou aux appareils de séparation, caractérisées par leur forme, leur structure ou leurs propriétésProcédés spécialement adaptés à leur fabrication caractérisées par leurs propriétés
A structured assembly of perpendicular, interwoven fluidic conduits permits connections between conduits to be readily (and in some cases visibly) established, thereby providing operational convenience and amenability to automated means of validation or verification.
F16L 41/03 - Ensembles de branchements, p. ex. d'une seule pièce, soudés à l'autogène, rivetés comportant des pièces d'assemblage pour quatre tuyaux ou plus
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
F16K 11/072 - Soupapes ou clapets à voies multiples, p. ex. clapets mélangeursRaccords de tuyauteries comportant de tels clapets ou soupapesAménagement d'obturateurs et de voies d'écoulement spécialement conçu pour mélanger les fluides dont toutes les faces d'obturation se déplacent comme un tout comportant uniquement des tiroirs à éléments de fermeture articulés à pivot
F16K 27/00 - Structures des logementsMatériaux utilisés à cet effet
F16K 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
Disclosed are tangential flow filtration (TFF) systems and methods. A system generally includes a TFF module, a control unit and one or more process-control components. In some cases, a system also includes a feed module. The control unit is electrically connected to the one or more process-control components and is configured to control the process of separation using the one or more process-control components. The systems and methods can maintain constant permeate flow rates to improve the predictability or consistence of the process, automatically switch membranes in case of membrane fouling, automatically promote membrane recovery, and/or permit operation of TFF systems in parallel with other processes in a manufacturing production.
A rotary valve may be operated by automated means and permits aseptic coupling of a source fluid conduit to any of a few or many possible outlet conduits. The valve assembly may be provided with numerous connectors for output coupling but it is not necessary to connect tubing to all of them.
F16K 11/085 - Soupapes ou clapets à voies multiples, p. ex. clapets mélangeursRaccords de tuyauteries comportant de tels clapets ou soupapesAménagement d'obturateurs et de voies d'écoulement spécialement conçu pour mélanger les fluides dont toutes les faces d'obturation se déplacent comme un tout comportant uniquement des robinets à boisseau à noix cylindrique
F16L 41/03 - Ensembles de branchements, p. ex. d'une seule pièce, soudés à l'autogène, rivetés comportant des pièces d'assemblage pour quatre tuyaux ou plus
A61F 5/00 - Procédés ou dispositifs d'orthopédie pour le traitement non chirurgical d'os ou articulationsDispositifs pour donner des soins
A61F 5/01 - Dispositifs orthopédiques, p. ex. dispositifs pour immobiliser ou pour exercer des pressions de façon durable pour le traitement des os fracturés ou déformés, tels que éclisses, plâtres orthopédiques ou attelles
A rotary valve may be operated by automated means and permits aseptic coupling of a source fluid conduit to any of a few or many possible outlet conduits. The valve assembly may be provided with numerous connectors for output coupling but it is not necessary to connect tubing to all of them.
F16K 7/16 - Dispositifs d'obturation à diaphragme, p. ex. dont un élément est déformé, sans être déplacé entièrement, pour fermer l'ouverture à diaphragme plat, en forme d'assiette ou en forme de bol disposé pour être déformé contre un siège plat le diaphragme étant actionné mécaniquement, p. ex. par une tige filetée ou par came
F16K 17/20 - Soupapes ou clapets limiteurs de débit
F16K 25/04 - Dispositions pour empêcher l'usure, non prévues ailleurs
F16K 27/02 - Structures des logementsMatériaux utilisés à cet effet des soupapes de levage
F16K 31/122 - Moyens de fonctionnementDispositifs de retour à la position de repos actionnés par un fluide le fluide agissant sur un piston
F16K 41/10 - Joints d'étanchéité pour tiges avec un diaphragme, p. ex. en forme de soufflet ou de tube
F16K 41/12 - Joints d'étanchéité pour tiges avec un diaphragme, p. ex. en forme de soufflet ou de tube le diaphragme étant sensiblement plat
An aseptic connector includes first and second matable housings each comprising a plurality of connectors for fluid conduits. The fluid conduits enter the housings and may be force-fitted onto barbs or flanges on one side of the connectors, or may instead be molded directly onto the connectors. When the housings are joined, the opposite sides of the connectors mate to form fluid seals, thereby establishing fluid pathways between now-connected sets of tubes.
A cell retention device includes a structured support with a plurality of circumferentially distributed ribs to retain the active filtering surface of a flexible, porous membrane filter medium. The filter medium surrounds the support in contact with the peaks of the ribs, thereby forming axial voids between the rib peaks. This arrangement imparts sufficient structural support over small regions of the filter medium to facilitate its use in a circular (or other rounded) configuration while providing sufficient channel volume to support high throughput of fluid sparse of cells.
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
B01D 69/02 - Membranes semi-perméables destinées aux procédés ou aux appareils de séparation, caractérisées par leur forme, leur structure ou leurs propriétésProcédés spécialement adaptés à leur fabrication caractérisées par leurs propriétés
A structured assembly of perpendicular, interwoven fluidic conduits permits connections between conduits to be readily (and in some cases visibly) established, thereby providing operational convenience and amenability to automated means of validation or verification.
F16L 41/03 - Ensembles de branchements, p. ex. d'une seule pièce, soudés à l'autogène, rivetés comportant des pièces d'assemblage pour quatre tuyaux ou plus
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
F16K 11/072 - Soupapes ou clapets à voies multiples, p. ex. clapets mélangeursRaccords de tuyauteries comportant de tels clapets ou soupapesAménagement d'obturateurs et de voies d'écoulement spécialement conçu pour mélanger les fluides dont toutes les faces d'obturation se déplacent comme un tout comportant uniquement des tiroirs à éléments de fermeture articulés à pivot
F16K 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe