Abstract

A structured assembly of perpendicular, interwoven fluidic conduits permits connections between conduits to be readily (and in some cases visibly) established, thereby providing operational convenience and amenability to automated means of validation or verification.

IPC Classes  ?

• F16L 41/03 - Branch units, e.g. made in one piece, welded, riveted comprising junction pieces for four or more pipe members
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• F16K 11/072 - Multiple-way valves, e.g. mixing valvesPipe fittings incorporating such valvesArrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only sliding valves with pivoted closure members
• F16K 27/00 - Construction of housingsUse of materials therefor
• F16K 99/00 - Subject matter not provided for in other groups of this subclass

Goods & Services

Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. Manufacturing services for others in the field of biotechnology. Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.

Goods & Services

Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. Manufacturing services for others in the field of biotechnology. Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.

Goods & Services

Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. Manufacturing services for others in the field of biotechnology. Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.

Goods & Services

Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. Manufacturing services for others in the field of biotechnology. Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.

Goods & Services

Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes; scientific apparatus for the biomanufacturing, expression, purification and collection of proteins and drug substances. Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field.

Goods & Services

Product research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; product research and development in the biotechnology field; platform as a service services (PaaS) featuring software for designing and developing protein fermentation processes; platform as a service services (PaaS) featuring software for collecting, analyzing, and reporting data related to biotechnology and protein manufacturing.

Goods & Services

Product research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; product research and development in the biotechnology field; platform as a service services (PaaS) featuring software for designing and developing protein fermentation processes; platform as a service services (PaaS) featuring software for collecting, analyzing, and reporting data related to biotechnology and protein manufacturing.

Goods & Services

Computer network server; computer network server for the secure electronic creation, transmission, storage, management, transfer, and retrieval of information related to biotechnology and protein manufacturing; network access server hardware; network access server hardware for the secure electronic creation, transmission, storage, management, transfer, and retrieval of information related to biotechnology and protein manufacturing.

Goods & Services

Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes.

Goods & Services

(1) Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. (1) Manufacturing services for others in the field of biotechnology. (2) Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.

Goods & Services

(1) Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. (1) Manufacturing services for others in the field of biotechnology. (2) Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.

Goods & Services

(1) Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. (1) Manufacturing services for others in the field of biotechnology. (2) Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.

Goods & Services

(1) Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes. (1) Manufacturing services for others in the field of biotechnology. (2) Product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; research and development in the biotechnology field.

Goods & Services

(1) Bioreactor system for perfusion fermentation; bioreactor system to continuously process and test parameters and collect data on a range of variables; bioreactor system for continuous protein, molecule, or cell line production using microbes.

Abstract

An aseptic connector includes first and second matable housings each comprising a plurality of connectors for fluid conduits. The fluid conduits enter the housings and may be force-fitted onto barbs or flanges on one side of the connectors, or may instead be molded directly onto the connectors. When the housings are joined, the opposite sides of the connectors mate to form fluid seals, thereby establishing fluid pathways between now-connected sets of tubes.

IPC Classes  ?

• A61M 39/14 - Tube connectors or tube couplings for connecting tubes having sealed ends
• A61M 39/10 - Tube connectors or tube couplings
• A61M 39/18 - Methods or apparatus for making the connection under sterile conditions, i.e. sterile docking
• F16L 37/56 - Couplings of the quick-acting type for double-walled or multi-channel pipes

Goods & Services

Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes, scientific apparatus for the biomanufacturing, expression, purification and collection of proteins and drug substances

Goods & Services

Manufacturing services for others in the field of biotechnology Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field

Goods & Services

Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbe

Goods & Services

Manufacturing services for others in the field of biotechnology Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field

Goods & Services

Manufacturing services for others in the field of biotechnology Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field

Goods & Services

Manufacturing services for others in the field of biotechnology Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field

Goods & Services

Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes

Goods & Services

Manufacturing services for others in the field of biotechnology Bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for perfusion fermentation; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel to continuously process and test parameters and collect data on a range of variables; bioreactor system comprised of a bioreactor for cell culturing, sensors, filters, and tubing attached to a rigid panel for continuous protein, molecule, or cell line production using microbes product development; product development in the fields of protein manufacturing; research and development of technology in the field of protein manufacturing; platform as a service services (PaaS) featuring software for designing and developing new products using protein manufacturing; Product research and development in the biotechnology field

Abstract

Described herein is a vessel cart including a base, a stand and a clamp. The base is configured to abut a lower portion of a vessel and hold the vessel upright when the vessel is loaded to the vessel card. The stand is connected to or formed with the base. The clamp is connected to the stand and configured to selectively grip an upper portion of the vessel. The clamp is also configured to open and close in a plane substantially parallel to a first surface of the base facing the clamp to allow the vessel to move laterally or radially relative to the clamp when the vessel is being loaded to the vessel cart or unloaded from the vessel cart.

IPC Classes  ?

• B62B 3/10 - Hand carts having more than one axis carrying transport wheelsSteering devices thereforEquipment therefor characterised by supports specially adapted to objects of definite shape
• B62B 3/04 - Hand carts having more than one axis carrying transport wheelsSteering devices thereforEquipment therefor involving means for grappling or securing in place objects to be carriedLoad handling equipment
• B62B 5/04 - Braking mechanismsLocking devices against movement
• B62B 5/06 - Hand moving equipment, e.g. handle bars
• B65D 25/20 - External fittings
• B65D 53/02 - Collars or rings

Abstract

Disclosed are systems and methods for alternately collecting a fluid in a plurality of containers without breaching its sterility. The system generally includes one or more collection modules, each having a valve and one or more container sets fluidically connected to the valve. Each container set includes first and second containers. The system also includes a control unit to control operation of the valve of each collection module to facilitate alternate collection of the fluid by the first and second containers of a container set. This may ensure that the fluid collected in one container is a true representative sample of the fluid collected in the container without compromising its sterile integrity.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

Abstract

A cell retention device includes a structured support with a plurality of circumferentially distributed ribs to retain the active filtering surface of a flexible, porous membrane filter medium. The filter medium surrounds the support in contact with the peaks of the ribs, thereby forming axial voids between the rib peaks. This arrangement imparts sufficient structural support over small regions of the filter medium to facilitate its use in a circular (or other rounded) configuration while providing sufficient channel volume to support high throughput of fluid sparse of cells.

IPC Classes  ?

• B01D 63/06 - Tubular membrane modules
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• B01D 71/16 - Cellulose acetate
• B01D 71/68 - PolysulfonesPolyethersulfones
• B01D 71/34 - Polyvinylidene fluoride
• C12M 1/00 - Apparatus for enzymology or microbiology
• C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means
• B01D 71/50 - Polycarbonates

Abstract

A structured assembly of perpendicular, interwoven fluidic conduits permits connections between conduits to be readily (and in some cases visibly) established, thereby providing operational convenience and amenability to automated means of validation or verification.

IPC Classes  ?

• F16L 41/03 - Branch units, e.g. made in one piece, welded, riveted comprising junction pieces for four or more pipe members
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• F16K 11/072 - Multiple-way valves, e.g. mixing valvesPipe fittings incorporating such valvesArrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only sliding valves with pivoted closure members
• F16K 27/00 - Construction of housingsUse of materials therefor
• F16K 99/00 - Subject matter not provided for in other groups of this subclass

Abstract

Disclosed are tangential flow filtration (TFF) systems and methods. A system generally includes a TFF module, a control unit and one or more process-control components. In some cases, a system also includes a feed module. The control unit is electrically connected to the one or more process-control components and is configured to control the process of separation using the one or more process-control components. The systems and methods can maintain constant permeate flow rates to improve the predictability or consistence of the process, automatically switch membranes in case of membrane fouling, automatically promote membrane recovery, and/or permit operation of TFF systems in parallel with other processes in a manufacturing production.

IPC Classes  ?

• B01D 61/12 - Controlling or regulating
• B01D 61/22 - Controlling or regulating

Abstract

A rotary valve may be operated by automated means and permits aseptic coupling of a source fluid conduit to any of a few or many possible outlet conduits. The valve assembly may be provided with numerous connectors for output coupling but it is not necessary to connect tubing to all of them.

IPC Classes  ?

• A61F 5/058 - Splints
• A61F 5/32 - Adjustable pressure pads
• F16K 11/085 - Multiple-way valves, e.g. mixing valvesPipe fittings incorporating such valvesArrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only taps or cocks with cylindrical plug
• F16L 41/03 - Branch units, e.g. made in one piece, welded, riveted comprising junction pieces for four or more pipe members

Abstract

A rotary valve may be operated by automated means and permits aseptic coupling of a source fluid conduit to any of a few or many possible outlet conduits. The valve assembly may be provided with numerous connectors for output coupling but it is not necessary to connect tubing to all of them.

IPC Classes  ?

• F16K 11/085 - Multiple-way valves, e.g. mixing valvesPipe fittings incorporating such valvesArrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only taps or cocks with cylindrical plug
• F16L 41/03 - Branch units, e.g. made in one piece, welded, riveted comprising junction pieces for four or more pipe members
• A61F 5/00 - Orthopaedic methods or devices for non-surgical treatment of bones or jointsNursing devices
• A61F 5/01 - Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces
• A61F 5/058 - Splints
• A61F 5/32 - Adjustable pressure pads

Abstract

A rotary valve may be operated by automated means and permits aseptic coupling of a source fluid conduit to any of a few or many possible outlet conduits. The valve assembly may be provided with numerous connectors for output coupling but it is not necessary to connect tubing to all of them.

IPC Classes  ?

• F16K 1/36 - Valve members
• F16K 1/42 - Valve seats
• F16K 7/16 - Diaphragm cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat the diaphragm being mechanically actuated, e.g. by screw-spindle or cam
• F16K 17/20 - Excess-flow valves
• F16K 25/04 - Arrangements for preventing erosion, not otherwise provided for
• F16K 27/02 - Construction of housingsUse of materials therefor of lift valves
• F16K 31/122 - Operating meansReleasing devices actuated by fluid the fluid acting on a piston
• F16K 41/10 - Spindle sealings with diaphragm, e.g. shaped as bellows or tube
• F16K 41/12 - Spindle sealings with diaphragm, e.g. shaped as bellows or tube with approximately flat diaphragm

Abstract

An aseptic connector includes first and second matable housings each comprising a plurality of connectors for fluid conduits. The fluid conduits enter the housings and may be force-fitted onto barbs or flanges on one side of the connectors, or may instead be molded directly onto the connectors. When the housings are joined, the opposite sides of the connectors mate to form fluid seals, thereby establishing fluid pathways between now-connected sets of tubes.

IPC Classes  ?

• A61M 39/10 - Tube connectors or tube couplings
• A61M 39/16 - Tube connectors or tube couplings having provision for disinfection or sterilisation
• A61M 39/18 - Methods or apparatus for making the connection under sterile conditions, i.e. sterile docking

Abstract

An aseptic connector includes first and second matable housings each comprising a plurality of connectors for fluid conduits. The fluid conduits enter the housings and may be force-fitted onto barbs or flanges on one side of the connectors, or may instead be molded directly onto the connectors. When the housings are joined, the opposite sides of the connectors mate to form fluid seals, thereby establishing fluid pathways between now-connected sets of tubes.

IPC Classes  ?

• A61M 39/14 - Tube connectors or tube couplings for connecting tubes having sealed ends
• F16L 37/56 - Couplings of the quick-acting type for double-walled or multi-channel pipes
• A61M 39/10 - Tube connectors or tube couplings
• A61M 39/08 - TubesStorage means specially adapted therefor
• A61M 39/18 - Methods or apparatus for making the connection under sterile conditions, i.e. sterile docking

Abstract

A structured assembly of perpendicular, interwoven fluidic conduits permits connections between conduits to be readily (and in some cases visibly) established, thereby providing operational convenience and amenability to automated means of validation or verification.

IPC Classes  ?

• C12M 1/00 - Apparatus for enzymology or microbiology
• C12M 3/06 - Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means

Abstract

A cell retention device includes a structured support with a plurality of circumferentially distributed ribs to retain the active filtering surface of a flexible, porous membrane filter medium. The filter medium surrounds the support in contact with the peaks of the ribs, thereby forming axial voids between the rib peaks. This arrangement imparts sufficient structural support over small regions of the filter medium to facilitate its use in a circular (or other rounded) configuration while providing sufficient channel volume to support high throughput of fluid sparse of cells.

IPC Classes  ?

• C12M 1/00 - Apparatus for enzymology or microbiology
• C12M 1/26 - Inoculator or sampler

Abstract

A cell retention device includes a structured support with a plurality of circumferentially distributed ribs to retain the active filtering surface of a flexible, porous membrane filter medium. The filter medium surrounds the support in contact with the peaks of the ribs, thereby forming axial voids between the rib peaks. This arrangement imparts sufficient structural support over small regions of the filter medium to facilitate its use in a circular (or other rounded) configuration while providing sufficient channel volume to support high throughput of fluid sparse of cells.

IPC Classes  ?

• B01D 63/06 - Tubular membrane modules
• C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• B01D 71/16 - Cellulose acetate
• B01D 71/68 - PolysulfonesPolyethersulfones
• B01D 71/34 - Polyvinylidene fluoride
• C12M 1/00 - Apparatus for enzymology or microbiology
• B01D 71/50 - Polycarbonates

Abstract

A structured assembly of perpendicular, interwoven fluidic conduits permits connections between conduits to be readily (and in some cases visibly) established, thereby providing operational convenience and amenability to automated means of validation or verification.

IPC Classes  ?

• F16L 41/03 - Branch units, e.g. made in one piece, welded, riveted comprising junction pieces for four or more pipe members
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• F16K 11/072 - Multiple-way valves, e.g. mixing valvesPipe fittings incorporating such valvesArrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only sliding valves with pivoted closure members
• F16K 99/00 - Subject matter not provided for in other groups of this subclass