Abrégé

The present invention relates to the development of a new live fowl typhoid (FT) vaccine candidate against Salmonella Gallinarum (SG), with two independent attenuating mutations based on metabolic drift (MD), spontaneous chromosomal mutations. Such vaccine candidate fulfills the security demand of the World Health Organization (WHO). The vaccine proved to be genetically stable, safe and effective in experimental studies. This attenuated vaccine strain is designed sufficiently invasive to induce immunity in poultry, in particular chickens, and the vaccinated animals were protected against experimental SG challenge. The vaccine can be used for chicken and can be administered orally which is an easy and cost effective alternative to injection.

Classes IPC  ?

• C12R 1/42 - Salmonella
• A61K 39/02 - Antigènes bactériens

Abrégé

Described is a method for the generation of a live vaccine containing stable bacteria carrying at least three attenuating mutations and a vaccine containing bacteria obtained by said method.

Classes IPC  ?

• C12R 1/42 - Salmonella
• A61K 39/02 - Antigènes bactériens
• A61K 39/112 - SalmonellaShigella

Abrégé

The invention relates to a new use of antioxidants for improving animal health. In particular, as a result of using antioxidants and also substances with an antioxidative effect, an increase or improvement in the endogenous radical defence system, a reduction in inflammatory processes and/or a prevention of and/or reduction in fertility problems is achieved.

Classes IPC  ?

• A23L 1/302 - Vitamines
• A61K 31/355 - Tocophérols, p. ex. vitamine E
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61K 31/047 - Composés hydroxylés, p. ex. alcoolsLeurs sels, p. ex. alcoolates ayant plusieurs groupes hydroxyle, p. ex. sorbitol
• A61K 31/05 - Phénols
• A61K 31/205 - Sels d'addition d'acides organiques avec des aminesSels d'ammonium quaternaire internes, p. ex. bétaïne, carnitine
• A61K 31/47 - QuinoléinesIsoquinoléines

Abrégé

Disclosed are a composition comprising an agent for stabilizing active substances in drinking water as well as an effervescent mixture.

Classes IPC  ?

• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 35/74 - Bactéries
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• C02F 1/68 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par addition de substances spécifiées, pour améliorer l'eau potable, p. ex. par addition d'oligo-éléments

Abrégé

Disclosed is a method for producing saponified, carotenoid-containing oleoresin, in which unsaponified, carotenoid-containing oleoresin is intensely mixed with a solid, small-sized and/or powdery alkali metal hydroxide, and the oleoresin is saponified during said process.

Classes IPC  ?

• A23K 1/16 - additionnés d'éléments nutritifs accessoires; Blocs de sel
• A23L 1/275 - Addition de colorants ou de pigments avec ou sans adjuvants optiques
• C09B 61/00 - Colorants naturels préparés à partir de sources naturelles