A tissue culture plate material retainer system includes a culture material retainer having a retainer ring with a retainer ring gap to enable the retainer ring to be compressed for insertion into a culture plate well and a plurality of retainer legs that extend down from the retainer ring to hold culture material down in the well of the culture plate in or under a culture medium. A culture material retainer has a retainer ring that extends along a top and a plurality of retainer legs that extend down from the retainer ring. The retainer ring extends from a first end to a second end forming a retainer ring gap that enables the retainer ring and culture material retainer to collapse or flex radially inward for insertion into a wall.
A tissue culture plate material retainer system includes a culture material retainer having a retainer ring with a retainer ring gap to enable the retainer ring to be compressed for insertion into a culture plate well and a plurality of retainer legs that extend down from the retainer ring to hold culture material down in the well of the culture plate in or under a culture medium. A culture material retainer has a retainer ring that extends along a top and a plurality of retainer legs that extend down from the retainer ring. The retainer ring extends from a first end to a second end forming a retainer ring gap that enables the retainer ring and culture material retainer to collapse or flex radially inward for insertion into a wall.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
03 - Produits cosmétiques et préparations de toilette; préparations pour blanchir, nettoyer, polir et abraser.
Produits et services
cosmetics, namely, non-medicinal liquid preparations including a component derived from human birth tissues to reduce the appearance of wrinkles, condition and revitalize the face, body, hands, feet, and to condition and revitalize hair; not for medical purposes
03 - Produits cosmétiques et préparations de toilette; préparations pour blanchir, nettoyer, polir et abraser.
Produits et services
cosmetics, namely, non-medicinal liquid preparations including a component derived from human birth tissues to reduce the appearance of wrinkles, condition and revitalize the face, body, hands, feet, and to condition and revitalize hair, not for medical purposes
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue
An enriched amnion derived tissue graft has a stromal matrix layer and an epithelium layer. A stromal matrix layer may contain a basement membrane layer, a compact layer, a fibroblast layer, and an intermediate layer. An amnion derived tissue graft may have a plurality of tissue layers and the layers may be configured with the epithelium layers toward the inside and the stromal matrix layers toward the outside surface. An enriched portion may be coated onto or be configured within a tissue layer and have an increased concentration of cells, of proteins, growth factors, seed cells, pharmaceuticals or any combination thereof. A carrier fluid such as amniotic fluid may be used to produce an enrichment composition for coating the tissue graft. The cells within the enriched portion may be stem cells from the amnion, or cells from other tissue and may be seed cells selected based on the treatment location.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
An allograft optimization system utilizes an optical system to determine the outer perimeter of a tissue blank for allograft cutting therefrom. The optical system determines an optimal allograft array pattern that can be derived from the irregular tissue blank and may include a plurality of various allograft shapes and sizes. A computer operates an allograft optimization computer program that receives input regarding the outer perimeter of the tissue blank. A cutting implement, such as a laser, is configured to cut the allografts from the irregularly shaped tissue blank according the allograft array pattern. The cutting implement is automatically actuated by an actuator with respect to the tissue blank to cut the allografts therefrom. The cutting implement may be a laser or a galvo laser that is directed by one or more mirrors. The tissue may be birth tissue including placental tissue and amnion.
B23K 26/38 - Enlèvement de matière par perçage ou découpage
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
B23K 26/402 - Enlèvement de matière en tenant compte des propriétés du matériau à enlever en faisant intervenir des matériaux non métalliques, p. ex. des isolants
B25J 13/08 - Commandes pour manipulateurs au moyens de dispositifs sensibles, p. ex. à la vue ou au toucher
B23K 37/04 - Dispositifs ou procédés auxiliaires non spécialement adaptés à un procédé couvert par un seul des autres groupes principaux de la présente sous-classe pour maintenir ou mettre en position les pièces
B23K 26/082 - Systèmes de balayage, c.-à-d. des dispositifs comportant un mouvement relatif entre le faisceau laser et la tête du laser
B25J 9/02 - Manipulateurs à commande programmée caractérisés par le mouvement des bras, p. ex. du type à coordonnées cartésiennes
An allograft optimization system utilizes an optical system to determine the outer perimeter of a tissue blank for allograft cutting therefrom. The optical system determines an optimal allograft array pattern that can be derived from the irregular tissue blank and may include a plurality of various allograft shapes and sizes. A computer operates an allograft optimization computer program that receives input regarding the outer perimeter of the tissue blank. A cutting implement, such as a laser, is configured to cut the allografts from the irregularly shaped tissue blank according the allograft array pattern. The cutting implement is automatically actuated by an actuator with respect to the tissue blank to cut the allografts therefrom. The cutting implement may be a laser or a galvo laser that is directed by one or more mirrors. The tissue may be birth tissue including placental tissue and amnion.
B23K 26/38 - Enlèvement de matière par perçage ou découpage
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
B23K 26/402 - Enlèvement de matière en tenant compte des propriétés du matériau à enlever en faisant intervenir des matériaux non métalliques, p. ex. des isolants
B25J 13/08 - Commandes pour manipulateurs au moyens de dispositifs sensibles, p. ex. à la vue ou au toucher
B23K 37/04 - Dispositifs ou procédés auxiliaires non spécialement adaptés à un procédé couvert par un seul des autres groupes principaux de la présente sous-classe pour maintenir ou mettre en position les pièces
B23K 26/082 - Systèmes de balayage, c.-à-d. des dispositifs comportant un mouvement relatif entre le faisceau laser et la tête du laser
B25J 9/02 - Manipulateurs à commande programmée caractérisés par le mouvement des bras, p. ex. du type à coordonnées cartésiennes
An allograft optimization system utilizes an optical system to determine the outer perimeter of a tissue blank for allograft cutting therefrom. The optical system determines an optimal allograft array pattern that can be derived from the irregular tissue blank and may include a plurality of various allograft shapes and sizes. A computer operates an allograft optimization computer program that receives input regarding the outer perimeter of the tissue blank. A cutting implement, such as a laser, is configured to cut the allografts from the irregularly shaped tissue blank according the allograft array pattern. The cutting implement is automatically actuated by an actuator with respect to the tissue blank to cut the allografts therefrom. The cutting implement may be a laser or a galvo laser that is directed by one or more mirrors. The tissue may be birth tissue including placental tissue and amnion.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Therapeutic products, namely, liquid preparations derived from growth factors of the human amnion for supplementation and for treatment to promote healing and rejuvenation of wounded bodily tissue
03 - Produits cosmétiques et préparations de toilette; préparations pour blanchir, nettoyer, polir et abraser.
Produits et services
cosmetics, namely, non-medicinal liquid preparations including a component derived from human birth tissues to reduce the appearance of wrinkles, condition and revitalize the face, body, hands, feet, and to condition and revitalize hair; not for medical purposes
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic cells. The amniotic cells may be destroyed and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized placental tissue particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic cells. The amniotic cells may be destroyed and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized placental tissue particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
An enriched amnion derived tissue graft has a stromal matrix layer and an epithelium layer. A stromal matrix layer may contain a basement membrane layer, a compact layer, a fibroblast layer, and an intermediate layer. An amnion derived tissue graft may have a plurality of tissue layers and the layers may be configured with the epithelium layers toward the inside and the stromal matrix layers toward the outside surface. An enriched portion may be coated onto or be configured within a tissue layer and have an increased concentration of cells, of proteins, growth factors, seed cells, pharmaceuticals or any combination thereof. A carrier fluid such as amniotic fluid may be used to produce an enrichment composition for coating the tissue graft. The cells within the enriched portion may be stem cells from the amnion, or cells from other tissue and may be seed cells selected based on the treatment location.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
A frozen therapeutic dose includes an amniotic material and is configured into a pack for easy administering of the dose to a treatment location. A frozen therapeutic dose may contain a concentration of live amniotic stem cells. A frozen therapeutic dose may be provided in a form, such as a multi-pack form, to enable a person to administer a dose to a treatment location without the need of traveling to a doctor's office or clinic. A frozen therapeutic dose package may be kept in a conventional freezer at −20° C. for example, for extended periods of time and a person may remove the package as needed for treatment. A frozen dose package or pack may contain a secondary material configured to mix with the frozen therapeutic dose. A secondary material may be configured within a single dose compartment with the frozen dose or within a separate compartment.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
A61K 8/98 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés d'origine animale
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A61K 47/20 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant du soufre, p. ex. sulfoxyde de diméthyle [DMSO], docusate, laurylsulfate de sodium ou acides aminosulfoniques
A61K 47/46 - Ingrédients de constitution indéterminée ou leurs produits de réaction, p. ex. peau, os, lait, fibre de coton, coquille d’œuf, fiel de bœuf ou extraits de plante
A61M 11/00 - Pulvérisateurs ou vaporisateurs spécialement destinés à des usages médicaux
6 amniotic stem cells per milliliter of fluid or composition. A therapeutic composite may be used to treat any number of conditions through topical application, surgical introduction, and/or injection.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Therapeutic products, namely, liquid preparations derived from human amnion and amniotic fluid for implantation and for topical treatment to promote healing and rejuvenation of wounded bodily tissue
24.
Method of treatment utilizing an acellular amnion derived therapeutic composition
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic cells. The amniotic cells may be destroyed, and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized placental tissue particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
A61Q 19/00 - Préparations pour les soins de la peau
A61Q 19/08 - Préparations contre le vieillissement
A61K 8/98 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés d'origine animale
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
Acellular amnion derived therapeutic compositions are described having a number of various com positional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic cells. The amniotic cells may be destroyed and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized placental tissue particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Therapeutic products, namely, liquid preparations derived from human amnion and amniotic fluid for implantation and for topical treatment to promote healing and rejuvenation of wounded bodily tissue
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic stems cells. The amniotic stem cells may be destroyed, and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized amniotic membrane particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
A frozen therapeutic dose includes an amniotic material and is configured into a pack for easy administering of the dose to a treatment location, A frozen therapeutic dose may contain a concentration of live amniotic stem cells. A frozen therapeutic dose may be provided in a form, such as a multi-pack form, to enable a person to administer a dose to a treatment location without the need of traveling to a doctor's office or clinic, A frozen therapeutic dose package may be kept in a conventional freezer at -20°C, for example, for extended periods of time and a person may remove the package as needed for treatment- A frozen dose package or pack may contain a secondary material configured to mix with the frozen therapeutic dose. A secondary material may be configured within a single dose compartment with the frozen dose or within a separate compartment.
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Human allograft tissue, namely, amniotic tissue allograft for topical or internal surgical applications for multiple surgical specialties including orthopedic, gynecology, urology, general, podiatry, and spine
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic stems cells. The amniotic stem cells may be destroyed, and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized amniotic membrane particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A61M 37/00 - Autres appareils pour introduire des agents dans le corpsPercutanisation, c.-à-d. introduction de médicaments dans le corps par diffusion à travers la peau
32.
AMNION DERIVED THERAPEUTIC COMPOSITIONS AND METHODS OF USE
Therapeutic composites are described for the treatment of a variety of organ related conditions. Any organ or organ system of the body may be treated including the pancreas, kidney, brain, lung, intestine and the like. A therapeutic composition may include a fluid component and a matrix component. A matrix component may be an amniotic membrane and a fluid component may be a fluid having a concentration of amniotic stem cells, and/or micronized amniotic membrane particles. An amniotic stem cell concentrated fluid has at least 0.1 x 10e amniotic stem cells per milliliter of fluid or composition. A therapeutic composition may be used to treat any number of conditions through topical application, injection, or intravenously. A matrix component may be located on a treatment location and a fluid component may subsequently be introduced to the matrix component or the surrounding tissue.
A61K 38/18 - Facteurs de croissanceRégulateurs de croissance
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
A61K 35/36 - PeauSystème pileuxOnglesGlandes sébacéesCérumenÉpidermeCellules épithélialesKératinocytesCellules de LangerhansCellules ectodermiques
A therapeutic composition may include a fluid component and/or a matrix component derived from amnion. A matrix component may be an amniotic membrane that is free of chorion. A fluid component may be a fluid having a concentration of stem cells, such as amniotic stem cells, and/or micronized amniotic membrane particles. A preferred fluid component includes micronized amniotic membrane particles dispersed in an amniotic stem cell concentrated fluid. An amniotic stem cell concentrated fluid has at least 0.1 x 106 amniotic stem cells per milliliter of fluid or composition, A therapeutic composite may be used to treat any number of heart related conditions through topical application, injection or through introduction intravenously. A matrix component may be located on a treatment location and a fluid component may be subsequently introduced to the matrix component.
A61K 38/18 - Facteurs de croissanceRégulateurs de croissance
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
Therapeutic composites are described for the treatment of joint, dermal, nerve and other orthopedic conditions. A therapeutic composite is a fluid that has micronized amniotic membrane particles and/or amniotic stem cells. A therapeutic composite may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. In another embodiment, the therapeutic composite is a mixture of micronized amniotic membrane particles combined with an amniotic rich stem cell fluid. An amniotic rich or concentrated stem cell fluid comprises at least 0.5 x 106 amniotic stem cells per milliliter of fluid or composition. A therapeutic composite may be used to treat any number of conditions through topical application, surgical introduction, and/or injection.
A61K 38/18 - Facteurs de croissanceRégulateurs de croissance
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Human allograft tissue, namely, amniotic tissue allograft for topical or internal surgical applications for multiple surgical specialties including orthopedic, gynecology, urology, general, podiatry, and spine
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Human allograft tissue, namely, amniotic tissue allograft for topical or internal surgical applications for multiple surgical specialties including orthopedic, gynecology, urology, general, podiatry, and spine
