A tissue culture plate material retainer system includes a culture material retainer having a retainer ring with a retainer ring gap to enable the retainer ring to be compressed for insertion into a culture plate well and a plurality of retainer legs that extend down from the retainer ring to hold culture material down in the well of the culture plate in or under a culture medium. A culture material retainer has a retainer ring that extends along a top and a plurality of retainer legs that extend down from the retainer ring. The retainer ring extends from a first end to a second end forming a retainer ring gap that enables the retainer ring and culture material retainer to collapse or flex radially inward for insertion into a wall.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
cosmetics, namely, non-medicinal liquid preparations including a component derived from human birth tissues to reduce the appearance of wrinkles, condition and revitalize the face, body, hands, feet, and to condition and revitalize hair; not for medical purposes
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
cosmetics, namely, non-medicinal liquid preparations including a component derived from human birth tissues to reduce the appearance of wrinkles, condition and revitalize the face, body, hands, feet, and to condition and revitalize hair, not for medical purposes
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue
An enriched amnion derived tissue graft has a stromal matrix layer and an epithelium layer. A stromal matrix layer may contain a basement membrane layer, a compact layer, a fibroblast layer, and an intermediate layer. An amnion derived tissue graft may have a plurality of tissue layers and the layers may be configured with the epithelium layers toward the inside and the stromal matrix layers toward the outside surface. An enriched portion may be coated onto or be configured within a tissue layer and have an increased concentration of cells, of proteins, growth factors, seed cells, pharmaceuticals or any combination thereof. A carrier fluid such as amniotic fluid may be used to produce an enrichment composition for coating the tissue graft. The cells within the enriched portion may be stem cells from the amnion, or cells from other tissue and may be seed cells selected based on the treatment location.
An allograft optimization system utilizes an optical system to determine the outer perimeter of a tissue blank for allograft cutting therefrom. The optical system determines an optimal allograft array pattern that can be derived from the irregular tissue blank and may include a plurality of various allograft shapes and sizes. A computer operates an allograft optimization computer program that receives input regarding the outer perimeter of the tissue blank. A cutting implement, such as a laser, is configured to cut the allografts from the irregularly shaped tissue blank according the allograft array pattern. The cutting implement is automatically actuated by an actuator with respect to the tissue blank to cut the allografts therefrom. The cutting implement may be a laser or a galvo laser that is directed by one or more mirrors. The tissue may be birth tissue including placental tissue and amnion.
B25J 13/08 - Controls for manipulators by means of sensing devices, e.g. viewing or touching devices
B23K 37/04 - Auxiliary devices or processes, not specially adapted for a procedure covered by only one of the other main groups of this subclass for holding or positioning work
B23K 26/082 - Scanning systems, i.e. devices involving movement of the laser beam relative to the laser head
B25J 9/02 - Programme-controlled manipulators characterised by movement of the arms, e.g. cartesian co-ordinate type
An allograft optimization system utilizes an optical system to determine the outer perimeter of a tissue blank for allograft cutting therefrom. The optical system determines an optimal allograft array pattern that can be derived from the irregular tissue blank and may include a plurality of various allograft shapes and sizes. A computer operates an allograft optimization computer program that receives input regarding the outer perimeter of the tissue blank. A cutting implement, such as a laser, is configured to cut the allografts from the irregularly shaped tissue blank according the allograft array pattern. The cutting implement is automatically actuated by an actuator with respect to the tissue blank to cut the allografts therefrom. The cutting implement may be a laser or a galvo laser that is directed by one or more mirrors. The tissue may be birth tissue including placental tissue and amnion.
B25J 13/08 - Controls for manipulators by means of sensing devices, e.g. viewing or touching devices
B23K 37/04 - Auxiliary devices or processes, not specially adapted for a procedure covered by only one of the other main groups of this subclass for holding or positioning work
B23K 26/082 - Scanning systems, i.e. devices involving movement of the laser beam relative to the laser head
B25J 9/02 - Programme-controlled manipulators characterised by movement of the arms, e.g. cartesian co-ordinate type
An allograft optimization system utilizes an optical system to determine the outer perimeter of a tissue blank for allograft cutting therefrom. The optical system determines an optimal allograft array pattern that can be derived from the irregular tissue blank and may include a plurality of various allograft shapes and sizes. A computer operates an allograft optimization computer program that receives input regarding the outer perimeter of the tissue blank. A cutting implement, such as a laser, is configured to cut the allografts from the irregularly shaped tissue blank according the allograft array pattern. The cutting implement is automatically actuated by an actuator with respect to the tissue blank to cut the allografts therefrom. The cutting implement may be a laser or a galvo laser that is directed by one or more mirrors. The tissue may be birth tissue including placental tissue and amnion.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid preparations derived from growth factors of the human amnion for supplementation and for treatment to promote healing and rejuvenation of wounded bodily tissue
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
cosmetics, namely, non-medicinal liquid preparations including a component derived from human birth tissues to reduce the appearance of wrinkles, condition and revitalize the face, body, hands, feet, and to condition and revitalize hair; not for medical purposes
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic cells. The amniotic cells may be destroyed and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized placental tissue particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic cells. The amniotic cells may be destroyed and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized placental tissue particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
An enriched amnion derived tissue graft has a stromal matrix layer and an epithelium layer. A stromal matrix layer may contain a basement membrane layer, a compact layer, a fibroblast layer, and an intermediate layer. An amnion derived tissue graft may have a plurality of tissue layers and the layers may be configured with the epithelium layers toward the inside and the stromal matrix layers toward the outside surface. An enriched portion may be coated onto or be configured within a tissue layer and have an increased concentration of cells, of proteins, growth factors, seed cells, pharmaceuticals or any combination thereof. A carrier fluid such as amniotic fluid may be used to produce an enrichment composition for coating the tissue graft. The cells within the enriched portion may be stem cells from the amnion, or cells from other tissue and may be seed cells selected based on the treatment location.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid and membrane preparations derived from human birth tissues for implantation and for treatment of wounded bodily tissues
A frozen therapeutic dose includes an amniotic material and is configured into a pack for easy administering of the dose to a treatment location. A frozen therapeutic dose may contain a concentration of live amniotic stem cells. A frozen therapeutic dose may be provided in a form, such as a multi-pack form, to enable a person to administer a dose to a treatment location without the need of traveling to a doctor's office or clinic. A frozen therapeutic dose package may be kept in a conventional freezer at −20° C. for example, for extended periods of time and a person may remove the package as needed for treatment. A frozen dose package or pack may contain a secondary material configured to mix with the frozen therapeutic dose. A secondary material may be configured within a single dose compartment with the frozen dose or within a separate compartment.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
A61K 8/98 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution of animal origin
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/46 - Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
A61M 11/00 - Sprayers or atomisers specially adapted for therapeutic purposes
6 amniotic stem cells per milliliter of fluid or composition. A therapeutic composite may be used to treat any number of conditions through topical application, surgical introduction, and/or injection.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid preparations derived from human amnion and amniotic fluid for implantation and for topical treatment to promote healing and rejuvenation of wounded bodily tissue
32.
Method of treatment utilizing an acellular amnion derived therapeutic composition
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic cells. The amniotic cells may be destroyed, and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized placental tissue particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
A61K 8/98 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution of animal origin
A61K 35/28 - Bone marrowHaematopoietic stem cellsMesenchymal stem cells of any origin, e.g. adipose-derived stem cells
Acellular amnion derived therapeutic compositions are described having a number of various com positional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic cells. The amniotic cells may be destroyed and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized placental tissue particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, amniotic patches applied to the skin that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue; Therapeutic products, namely, amniotic patches applied to internal organs and bodily tissues that are derived from human amnion for implantation and for topical treatment all to promote healing and rejuvenation of wounded bodily tissue
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Therapeutic products, namely, liquid preparations derived from human amnion and amniotic fluid for implantation and for topical treatment to promote healing and rejuvenation of wounded bodily tissue
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic stems cells. The amniotic stem cells may be destroyed, and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized amniotic membrane particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
A frozen therapeutic dose includes an amniotic material and is configured into a pack for easy administering of the dose to a treatment location, A frozen therapeutic dose may contain a concentration of live amniotic stem cells. A frozen therapeutic dose may be provided in a form, such as a multi-pack form, to enable a person to administer a dose to a treatment location without the need of traveling to a doctor's office or clinic, A frozen therapeutic dose package may be kept in a conventional freezer at -20°C, for example, for extended periods of time and a person may remove the package as needed for treatment- A frozen dose package or pack may contain a secondary material configured to mix with the frozen therapeutic dose. A secondary material may be configured within a single dose compartment with the frozen dose or within a separate compartment.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Human allograft tissue, namely, amniotic tissue allograft for topical or internal surgical applications for multiple surgical specialties including orthopedic, gynecology, urology, general, podiatry, and spine
Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic stems cells. The amniotic stem cells may be destroyed, and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized amniotic membrane particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
Therapeutic composites are described for the treatment of a variety of organ related conditions. Any organ or organ system of the body may be treated including the pancreas, kidney, brain, lung, intestine and the like. A therapeutic composition may include a fluid component and a matrix component. A matrix component may be an amniotic membrane and a fluid component may be a fluid having a concentration of amniotic stem cells, and/or micronized amniotic membrane particles. An amniotic stem cell concentrated fluid has at least 0.1 x 10e amniotic stem cells per milliliter of fluid or composition. A therapeutic composition may be used to treat any number of conditions through topical application, injection, or intravenously. A matrix component may be located on a treatment location and a fluid component may subsequently be introduced to the matrix component or the surrounding tissue.
A therapeutic composition may include a fluid component and/or a matrix component derived from amnion. A matrix component may be an amniotic membrane that is free of chorion. A fluid component may be a fluid having a concentration of stem cells, such as amniotic stem cells, and/or micronized amniotic membrane particles. A preferred fluid component includes micronized amniotic membrane particles dispersed in an amniotic stem cell concentrated fluid. An amniotic stem cell concentrated fluid has at least 0.1 x 106 amniotic stem cells per milliliter of fluid or composition, A therapeutic composite may be used to treat any number of heart related conditions through topical application, injection or through introduction intravenously. A matrix component may be located on a treatment location and a fluid component may be subsequently introduced to the matrix component.
Therapeutic composites are described for the treatment of joint, dermal, nerve and other orthopedic conditions. A therapeutic composite is a fluid that has micronized amniotic membrane particles and/or amniotic stem cells. A therapeutic composite may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. In another embodiment, the therapeutic composite is a mixture of micronized amniotic membrane particles combined with an amniotic rich stem cell fluid. An amniotic rich or concentrated stem cell fluid comprises at least 0.5 x 106 amniotic stem cells per milliliter of fluid or composition. A therapeutic composite may be used to treat any number of conditions through topical application, surgical introduction, and/or injection.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Human allograft tissue, namely, amniotic tissue allograft for topical or internal surgical applications for multiple surgical specialties including orthopedic, gynecology, urology, general, podiatry, and spine
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Human allograft tissue, namely, amniotic tissue allograft for topical or internal surgical applications for multiple surgical specialties including orthopedic, gynecology, urology, general, podiatry, and spine
