A method for fast measurement of crude polysaccharide in ganoderma lucidum spore powder, comprising: performing pretreatment on a ganoderma lucidum spore powder sample to obtain a solution to be measured; preparing an anhydrous glucose standard solution; drawing a standard curve; and measuring the content of crude polysaccharide in the ganoderma lucidum spore powder sample. The pretreatment on the ganoderma lucidum spore powder sample comprises the following steps: weighing a 0.5-2 g sample; adding 70-90 ml of purified water; heating the mixture and keeping slight boiling for 0.5 h; taking the mixture out; cooling the mixture to the room temperature; bring the volume of the mixture to 100 ml; uniformly shaking and filtering the mixture; taking 10 ml of the filtrate for drying; dissolving the product with 2 ml of purified water; then adding 30 ml of absolute ethyl alcohol; uniformly shaking the mixture; performing standing for 5 min; centrifuging the mixture; taking out the precipitate and adding water to dissolve the precipitate, and bringing the mixture to volume in a 25 ml volumetric flask; and diluting the mixture for 5 times to obtain the solution to be measured. Steps can be remarkably simplified, the measurement time can be shortened, loss of active components can be reduced, and the result is stable.
G01N 21/31 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique
A method for improving the cell-wall breaking rate of a Ganoderma lucidum spore powder. The method comprises: gradually feeding materials between roller surfaces of two rollers of a Ganoderma lucidum spore powder cell-wall breaking machine; synchronously and uniformly spraying water on the Ganoderma lucidum spore powder between the rolling double-rollers, wherein the total water spraying amount is 30-35% of the total feeding weight; and then receiving the materials below the rollers by using a material receiving tray, and returning the received materials to the roller surface to perform rolling and cell-wall breaking multiple times.
B02C 23/40 - Addition de fluide, dans un but autre que celui de broyer ou de désagréger par l'énergie du fluide avec plusieurs moyens pour ajouter le fluide au matériau en cours de broyage ou de désagrégation
3.
METHOD FOR PREPARING HIGH-CONTENT GANODERMA TRITERPENE EXTRACT
Disclosed is a method for preparing a high-content Ganoderma triterpene extract, comprising the following steps of: carrying out ultrasonic extraction on a dry Ganoderma powder with water 2-3 times, with 30-90 minutes each time, filtering, combining obtained filtrates, drying to obtain a Ganoderma aqueous extract solid, adding ethanol to the Ganoderma aqueous extract solid, carrying out ultrasonic extraction for 30-90 minutes, filtering, and drying an obtained filtrate at a low temperature to obtain the high-content Ganoderma triterpene extract. The present invention can save a large amount of ethanol, the extraction efficiency is high, and the obtained solid has a high content of Ganoderma triterpene.
222 supercritical extraction to obtain ganoderma lucidum spore oil which does not contain fat-soluble harmful ingredients, is fragrant and has long storage life. The method realizes quick operation and low energy consumption and is suitable for mass production and processing; effective active ingredients of the ganoderma lucidum spore powder are retained while the fat-soluble harmful ingredients are effectively removed; and the safety, effectiveness and quality controllability of the ganoderma lucidum spore oil are all taken into consideration.
222 of 50-90 L/h; controlling the pressure of a separation kettle I to be 7-12 MPa and the temperature to be 35-55ºC; controlling the pressure of a separation kettle II to be 4-6 MPa and the temperature to be 25-45ºC; carrying out extraction, with an extraction time of 0.5-3 h; and taking out an extract after extraction is completed.
A method for preparing a lycopene-containing composition with an anti-aging effect, the method comprising: mixing lycopene oleoresin with a small amount of absolute ethanol to obtain a lycopene oleoresin alcoholate, putting nicotinamide mononucleotide into a fluidized bed granulator, atomizing the lycopene oleoresin alcoholate through a nozzle by means of compressed air, spraying the atomized lycopene oleoresin alcoholate onto the nicotinamide mononucleotide powder in a fluidized state on a fluidized bed layer to wet same, fully mixing the lycopene oleoresin alcoholate and the nicotinamide mononucleotide powder, and then carrying out flow granulation, wherein the conditions used for spray granulation are an atomizing speed of 40-100 mL/min through the nozzle and an atomizing particle size of 10-12 μm. The prepared anti-aging composition can effectively improve the lifespan and climbing ability of Drosophila melanogaster, can also effectively improve the MDA level in rat serum and the SOD activity in the rat serum, and has a remarkable anti-aging effect. In addition, a granular product has a high effective ingredient content and a good stability.
A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
Disclosed is a method for preparing Ganoderma lucidum extract oil rich in Ganoderma lucidum triterpene. The method comprises: separately granulating Ganoderma lucidum fine powder and wall-broken Ganoderma lucidum spore powder to obtain Ganoderma lucidum fruiting body particles and Ganoderma lucidum spore powder particles, then successively and respectively drying the obtained two particles, and after mixing the two, subjecting same to supercritical carbon dioxide extraction. Finally, the content of the Ganoderma lucidum triterpene in the prepared Ganoderma lucidum extract oil is higher than the content of the Ganoderma lucidum triterpene in the Ganoderma lucidum spore oil and the extract oil has a significant anti-tumor pharmacological activity.
ZHONGKE HEALTH INDUSTRY GROUP JIANGSU PHARMACEUTICAL CO., LTD. (Chine)
Inventeur(s)
Qian, Yifan
Feng, Peng
Zhou, Yajie
Wang, Lianan
Shen, Jian
Feng, Min
Abrégé
Disclosed are a Ganoderma lucidum spore extract and an application thereof. The Ganoderma lucidum spore extract is prepared by the following method: breaking and crushing and defatting a Ganoderma lucidum spore powder, to obtain a defatted spore powder and a volatile oil, subjecting the defatted spore powder to water extraction and filtering, merging the filtrate, concentrating the filtrate and then adding ethanol and standing for precipitation, performing filtration to obtain a supernatant, recovering ethanol from the supernatant, and concentrating the supernatant to a relative density of 1.1-1.2 to obtain an extract. The present invention makes full use of remaining products from production of Ganoderma lucidum spore oil and Ganoderma lucidum spore polysaccharides, and comprehensively develops a Ganoderma lucidum spore powder. This is in line with the concept of green and environmentally friendly production, while significantly reducing production costs of enterprises.
A61K 131/00 - Parties de plantes contenant des graines ou des semences, des noix ou des noisettes, des fruits ou des grains, ou obtenues à partir de ces éléments
ZHONGKE HEALTH INDUSTRY GROUP JIANGSU PHARMACEUTICAL CO., LTD. (Chine)
Inventeur(s)
Feng, Peng
Wang, Lianan
Chen, Heng
Zhou, Yajie
Qian, Yifan
Peng, Yajuan
Abrégé
Disclosed is a preparation method for deer velvet alcohol. The method comprises: freeze-drying fresh deer velvet, adding same into a 40-53 ° alcohol base at a 1:20-500 ratio, utilizing ultrasonic reflux extraction, and after centrifugation of an extract liquid, obtaining a supernatant liquid. A method of the present invention amply preserves various active components in fresh deer velvet, prepared deer antler alcohol has a clarified color, a rich, deep taste, and is free of foul or bitter flavors.
ZHONGKE HEALTH INDUSTRY GROUP JIANGSU PHARMACEUTICAL CO., LTD. (Chine)
Inventeur(s)
Feng, Peng
Wang, Lianan
Wang, Ying
Zhou, Yajie
Qian, Yifan
Feng, Min
Abrégé
22 supercritical extraction process to obtain degreased Ganoderma lucidum spore powder; and mixing the degreased Ganoderma lucidum spore powder and lycopene oil resin at a weight ratio of (1-2):(1-2), and performing spray granulation on same. In a granular product prepared by using the method, the effective component content is high, the lycopene content is more than 6%, and the polysaccharide content is more than 0.8%; and the product has good stability and has an efficient antioxidation effect.
A61K 47/46 - Ingrédients de constitution indéterminée ou leurs produits de réaction, p. ex. peau, os, lait, fibre de coton, coquille d’œuf, fiel de bœuf ou extraits de plante
ZHONGKE HEALTH INDUSTRY GROUP JIANGSU PHARMACEUTICAL CO., LTD. (Chine)
Inventeur(s)
Feng, Peng
Wang, Lianan
Zhou, Yajie
Han, Fengcheng
Chen, Liang
Feng, Ruixuan
Abrégé
A vacuum drier and a drying method thereof. The vacuum drier comprises: a drier body used for accommodating a material to be dried for drying; a vacuum meter and a thermometer, wherein the vacuum meter and the thermometer are arranged in the drier body, the vacuum meter is used for detecting a vacuum degree in the drier body, and the thermometer is used for detecting a temperature in the drier body; and a drying rack arranged in the drier body, wherein the drying rack is of a layered rectangular frame structure, each layer of the rectangular frame is a tubular drying pipe, and the rectangular frames are in communication with one another. The defects that in the prior art, in an existing vacuum drier, a vacuum pump and a valve for introducing steam are manually controlled according to a temperature displayed by a thermometer, which results in a low operation efficiency and abnormally wasted time and labor, are effectively avoided.
F26B 9/06 - Machines ou appareils pour le séchage d'un matériau solide ou d'objets au repos animés uniquement d'une agitation localeAération des placards ou armoires d'appartements dans des tambours ou chambres fixes
12.
MICROWAVE VACUUM DRYING DEVICE AND DRYING PROCESS THEREOF
ZHONGKE HEALTH INDUSTRY GROUP JIANGSU PHARMACEUTICAL CO., LTD. (Chine)
Inventeur(s)
Zhou, Yajie
Feng, Peng
Wang, Lianan
Peng, Yajuan
Chen, Liang
Feng, Ruixuan
Abrégé
A microwave vacuum drying device and a drying process thereof. The drying device comprises a microwave generator (1), a vacuum drying chamber (2), a material rotating disk mechanism, a vacuum system, and a control system; the microwave generator (1) comprises microwave magnetrons and a microwave transformer electrically connected thereto, and an alternating current contactor is connected in series between each microwave magnetron and the microwave transformer; each microwave magnetron is connected in series to an independent protection device that prevents short-circuiting and overload; the vacuum drying chamber (2) is a hollow container, and both the microwave generator and the material rotating disk mechanism are disposed in the vacuum drying chamber (2); the material rotating disk mechanism enables a material to do circular motion in the vacuum drying chamber (2). The drying process comprises four steps: power on, entering to a main operation interface of a touch screen, parameter setting, and manual operation.
F26B 11/04 - Machines ou appareils à mouvement non progressif pour le séchage d'un matériau solide ou d'objets dans des tambours ou autres récipients quasi fermés, mobiles tournant autour d'un axe horizontal ou légèrement incliné
F26B 3/347 - Chauffage électromagnétique, p. ex. chauffage par induction ou par micro-ondes
F26B 5/04 - Procédés de séchage d'un matériau solide ou d'objets n'impliquant pas l'utilisation de chaleur par évaporation ou sublimation de l'humidité sous une pression réduite, p. ex. sous vide
F26B 23/08 - Chauffage utilisant un chauffage électrique par inductionChauffage utilisant un chauffage électrique capacitifChauffage utilisant un chauffage électrique par micro-ondes
F26B 25/00 - Parties constitutives d'application générale non couvertes par un des groupes ou
ZHONGKE HEALTH INDUSTRY GROUP JIANGSU PHARMACEUTICAL CO., LTD. (Chine)
NANJING ZHONGKE PHARMACEUTICAL CO., LTD. (Chine)
Inventeur(s)
Wang, Yunpeng
Qian, Yifan
Shi, Weiwei
Guo, Yuan
Hua, Kewei
Zhu, Yunyun
Chen, Suling
Abrégé
Disclosed by the present invention is a separation and purification method for polysaccharide in ganoderma lucidum spores, the method comprising: carrying out ultrasonic extraction on degreased ganoderma lucidum spore powder; and after frame filtration, carrying out precipitation and filtration on the obtained filtrate by means of ethanol having a mass concentration of 75% and ethanol having mass concentration of 85%. The obtained polysaccharide has an obvious effect for inhibiting the transplanted tumors of animals.
A processing method of cordyceps sinensis mycelium, comprising the following steps: cultivating a Hirsutella hepiali Chen et Shen to obtain a mycelium, conducting ultrasonic extraction by using 30-50 wt% of ethyl alcohol, filtering by using a membrane with a molecular weight of 2000-4000 Daltons, centrifugalizing, discarding a precipitate, extracting a supernatant, and cooling and drying to obtain a concentrated freeze-dried mycelium powder.
Disclosed is a lycopene microcapsule preparation method, comprising the steps of: firstly preparing the lycopene into a core material, and then homogeneously emulsifying and spray-drying the core material and a wall material; the wall material is prepared from gelatin, sporoderm-broken ganoderma lucidum spore powder, cane sugar and skim milk powder in a weight ratio of 1: 1: 1: 1.2-1.6, and the core material is prepared from the lycopene, salad oil and sucrose ester. The present invention employs a specific microcapsule technique to embed the lycopene, and improves both stability and water solubility of the lycopene microcapsule, thus further expanding the application scope.
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