Abstract

A method for fast measurement of crude polysaccharide in ganoderma lucidum spore powder, comprising: performing pretreatment on a ganoderma lucidum spore powder sample to obtain a solution to be measured; preparing an anhydrous glucose standard solution; drawing a standard curve; and measuring the content of crude polysaccharide in the ganoderma lucidum spore powder sample. The pretreatment on the ganoderma lucidum spore powder sample comprises the following steps: weighing a 0.5-2 g sample; adding 70-90 ml of purified water; heating the mixture and keeping slight boiling for 0.5 h; taking the mixture out; cooling the mixture to the room temperature; bring the volume of the mixture to 100 ml; uniformly shaking and filtering the mixture; taking 10 ml of the filtrate for drying; dissolving the product with 2 ml of purified water; then adding 30 ml of absolute ethyl alcohol; uniformly shaking the mixture; performing standing for 5 min; centrifuging the mixture; taking out the precipitate and adding water to dissolve the precipitate, and bringing the mixture to volume in a 25 ml volumetric flask; and diluting the mixture for 5 times to obtain the solution to be measured. Steps can be remarkably simplified, the measurement time can be shortened, loss of active components can be reduced, and the result is stable.

IPC Classes  ?

• G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
• G01N 1/34 - PurifyingCleaning

Abstract

A method for improving the cell-wall breaking rate of a Ganoderma lucidum spore powder. The method comprises: gradually feeding materials between roller surfaces of two rollers of a Ganoderma lucidum spore powder cell-wall breaking machine; synchronously and uniformly spraying water on the Ganoderma lucidum spore powder between the rolling double-rollers, wherein the total water spraying amount is 30-35% of the total feeding weight; and then receiving the materials below the rollers by using a material receiving tray, and returning the received materials to the roller surface to perform rolling and cell-wall breaking multiple times.

IPC Classes  ?

• B02C 4/02 - Crushing or disintegrating by roller mills with two or more rollers
• B02C 4/28 - Crushing or disintegrating by roller mills Details
• B02C 4/30 - Shape or construction of rollers
• B02C 4/40 - Detachers, e.g. scrapers
• B02C 4/44 - Cooling or heating rollers or bars
• B02C 19/08 - Pestle and mortar
• B02C 23/40 - Adding fluid, other than for crushing or disintegrating by fluid energy with more than one means for adding fluid to the material being crushed or disintegrated

Abstract

Disclosed is a method for preparing a high-content Ganoderma triterpene extract, comprising the following steps of: carrying out ultrasonic extraction on a dry Ganoderma powder with water 2-3 times, with 30-90 minutes each time, filtering, combining obtained filtrates, drying to obtain a Ganoderma aqueous extract solid, adding ethanol to the Ganoderma aqueous extract solid, carrying out ultrasonic extraction for 30-90 minutes, filtering, and drying an obtained filtrate at a low temperature to obtain the high-content Ganoderma triterpene extract. The present invention can save a large amount of ethanol, the extraction efficiency is high, and the obtained solid has a high content of Ganoderma triterpene.

IPC Classes  ?

• A61K 36/074 - Ganoderma
• B01D 11/02 - Solvent extraction of solids

Abstract

222 supercritical extraction to obtain ganoderma lucidum spore oil which does not contain fat-soluble harmful ingredients, is fragrant and has long storage life. The method realizes quick operation and low energy consumption and is suitable for mass production and processing; effective active ingredients of the ganoderma lucidum spore powder are retained while the fat-soluble harmful ingredients are effectively removed; and the safety, effectiveness and quality controllability of the ganoderma lucidum spore oil are all taken into consideration.

IPC Classes  ?

• C11B 1/10 - Production of fats or fatty oils from raw materials by extracting
• C11B 1/04 - Pretreatment of vegetable raw material

Abstract

222 of 50-90 L/h; controlling the pressure of a separation kettle I to be 7-12 MPa and the temperature to be 35-55ºC; controlling the pressure of a separation kettle II to be 4-6 MPa and the temperature to be 25-45ºC; carrying out extraction, with an extraction time of 0.5-3 h; and taking out an extract after extraction is completed.

IPC Classes  ?

• B01D 11/02 - Solvent extraction of solids
• A61K 36/074 - Ganoderma

Abstract

A method for preparing a lycopene-containing composition with an anti-aging effect, the method comprising: mixing lycopene oleoresin with a small amount of absolute ethanol to obtain a lycopene oleoresin alcoholate, putting nicotinamide mononucleotide into a fluidized bed granulator, atomizing the lycopene oleoresin alcoholate through a nozzle by means of compressed air, spraying the atomized lycopene oleoresin alcoholate onto the nicotinamide mononucleotide powder in a fluidized state on a fluidized bed layer to wet same, fully mixing the lycopene oleoresin alcoholate and the nicotinamide mononucleotide powder, and then carrying out flow granulation, wherein the conditions used for spray granulation are an atomizing speed of 40-100 mL/min through the nozzle and an atomizing particle size of 10-12 μm. The prepared anti-aging composition can effectively improve the lifespan and climbing ability of Drosophila melanogaster, can also effectively improve the MDA level in rat serum and the SOD activity in the rat serum, and has a remarkable anti-aging effect. In addition, a granular product has a high effective ingredient content and a good stability.

IPC Classes  ?

• A61K 31/706 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
• A61K 31/01 - Hydrocarbons
• A61P 39/06 - Free radical scavengers or antioxidants

Abstract

Disclosed is a method for preparing Ganoderma lucidum extract oil rich in Ganoderma lucidum triterpene. The method comprises: separately granulating Ganoderma lucidum fine powder and wall-broken Ganoderma lucidum spore powder to obtain Ganoderma lucidum fruiting body particles and Ganoderma lucidum spore powder particles, then successively and respectively drying the obtained two particles, and after mixing the two, subjecting same to supercritical carbon dioxide extraction. Finally, the content of the Ganoderma lucidum triterpene in the prepared Ganoderma lucidum extract oil is higher than the content of the Ganoderma lucidum triterpene in the Ganoderma lucidum spore oil and the extract oil has a significant anti-tumor pharmacological activity.

IPC Classes  ?

• C11B 9/02 - Recovery or refining of essential oils from raw materials
• A61K 36/074 - Ganoderma
• A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A61P 35/04 - Antineoplastic agents specific for metastasis
• A23P 10/30 - Encapsulation of particles, e.g. foodstuff additives

Abstract

Disclosed are a Ganoderma lucidum spore extract and an application thereof. The Ganoderma lucidum spore extract is prepared by the following method: breaking and crushing and defatting a Ganoderma lucidum spore powder, to obtain a defatted spore powder and a volatile oil, subjecting the defatted spore powder to water extraction and filtering, merging the filtrate, concentrating the filtrate and then adding ethanol and standing for precipitation, performing filtration to obtain a supernatant, recovering ethanol from the supernatant, and concentrating the supernatant to a relative density of 1.1-1.2 to obtain an extract. The present invention makes full use of remaining products from production of Ganoderma lucidum spore oil and Ganoderma lucidum spore polysaccharides, and comprehensively develops a Ganoderma lucidum spore powder. This is in line with the concept of green and environmentally friendly production, while significantly reducing production costs of enterprises.

IPC Classes  ?

• A61K 36/074 - Ganoderma
• A61P 1/14 - Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
• A61K 131/00 - Containing or obtained from seeds, nuts, fruits or grains

Abstract

Disclosed is a preparation method for deer velvet alcohol. The method comprises: freeze-drying fresh deer velvet, adding same into a 40-53 ° alcohol base at a 1:20-500 ratio, utilizing ultrasonic reflux extraction, and after centrifugation of an extract liquid, obtaining a supernatant liquid. A method of the present invention amply preserves various active components in fresh deer velvet, prepared deer antler alcohol has a clarified color, a rich, deep taste, and is free of foul or bitter flavors.

IPC Classes  ?

• C12G 3/00 - Preparation of other alcoholic beverages
• A61K 35/32 - BonesOsteocytesOsteoblastsTendonsTenocytesTeethOdontoblastsCartilageChondrocytesSynovial membrane
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
• A61P 1/14 - Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
• A61P 7/06 - Antianaemics
• A61P 15/10 - Drugs for genital or sexual disordersContraceptives for impotence
• A61P 19/08 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Abstract

22 supercritical extraction process to obtain degreased Ganoderma lucidum spore powder; and mixing the degreased Ganoderma lucidum spore powder and lycopene oil resin at a weight ratio of (1-2):(1-2), and performing spray granulation on same. In a granular product prepared by using the method, the effective component content is high, the lycopene content is more than 6%, and the polysaccharide content is more than 0.8%; and the product has good stability and has an efficient antioxidation effect.

IPC Classes  ?

• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 31/01 - Hydrocarbons
• A61K 36/074 - Ganoderma
• A61K 47/46 - Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
• A61P 39/06 - Free radical scavengers or antioxidants

Abstract

A vacuum drier and a drying method thereof. The vacuum drier comprises: a drier body used for accommodating a material to be dried for drying; a vacuum meter and a thermometer, wherein the vacuum meter and the thermometer are arranged in the drier body, the vacuum meter is used for detecting a vacuum degree in the drier body, and the thermometer is used for detecting a temperature in the drier body; and a drying rack arranged in the drier body, wherein the drying rack is of a layered rectangular frame structure, each layer of the rectangular frame is a tubular drying pipe, and the rectangular frames are in communication with one another. The defects that in the prior art, in an existing vacuum drier, a vacuum pump and a valve for introducing steam are manually controlled according to a temperature displayed by a thermometer, which results in a low operation efficiency and abnormally wasted time and labor, are effectively avoided.

IPC Classes  ?

• F26B 9/06 - Machines or apparatus for drying solid materials or objects at rest or with only local agitationDomestic airing cupboards in stationary drums or chambers

Abstract

A microwave vacuum drying device and a drying process thereof. The drying device comprises a microwave generator (1), a vacuum drying chamber (2), a material rotating disk mechanism, a vacuum system, and a control system; the microwave generator (1) comprises microwave magnetrons and a microwave transformer electrically connected thereto, and an alternating current contactor is connected in series between each microwave magnetron and the microwave transformer; each microwave magnetron is connected in series to an independent protection device that prevents short-circuiting and overload; the vacuum drying chamber (2) is a hollow container, and both the microwave generator and the material rotating disk mechanism are disposed in the vacuum drying chamber (2); the material rotating disk mechanism enables a material to do circular motion in the vacuum drying chamber (2). The drying process comprises four steps: power on, entering to a main operation interface of a touch screen, parameter setting, and manual operation.

IPC Classes  ?

• F26B 11/04 - Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles rotating about a horizontal or slightly-inclined axis
• F26B 3/347 - Electromagnetic heating, e.g. induction heating or heating using microwave energy
• F26B 5/04 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
• F26B 23/08 - Heating arrangements using electric heating inductive heatingHeating arrangements using electric heating capacitative heatingHeating arrangements using electric heating microwave heating
• F26B 25/00 - Details of general application not covered by group or
• F26B 25/06 - Chambers, containers, or receptacles

Abstract

Disclosed by the present invention is a separation and purification method for polysaccharide in ganoderma lucidum spores, the method comprising: carrying out ultrasonic extraction on degreased ganoderma lucidum spore powder; and after frame filtration, carrying out precipitation and filtration on the obtained filtrate by means of ethanol having a mass concentration of 75% and ethanol having mass concentration of 85%. The obtained polysaccharide has an obvious effect for inhibiting the transplanted tumors of animals.

IPC Classes  ?

• C08B 37/00 - Preparation of polysaccharides not provided for in groups Derivatives thereof

Abstract

A processing method of cordyceps sinensis mycelium, comprising the following steps: cultivating a Hirsutella hepiali Chen et Shen to obtain a mycelium, conducting ultrasonic extraction by using 30-50 wt% of ethyl alcohol, filtering by using a membrane with a molecular weight of 2000-4000 Daltons, centrifugalizing, discarding a precipitate, extracting a supernatant, and cooling and drying to obtain a concentrated freeze-dried mycelium powder.

IPC Classes  ?

• A61K 36/068 - Cordyceps
• A61P 37/04 - Immunostimulants

Abstract

Disclosed is a lycopene microcapsule preparation method, comprising the steps of: firstly preparing the lycopene into a core material, and then homogeneously emulsifying and spray-drying the core material and a wall material; the wall material is prepared from gelatin, sporoderm-broken ganoderma lucidum spore powder, cane sugar and skim milk powder in a weight ratio of 1: 1: 1: 1.2-1.6, and the core material is prepared from the lycopene, salad oil and sucrose ester. The present invention employs a specific microcapsule technique to embed the lycopene, and improves both stability and water solubility of the lycopene microcapsule, thus further expanding the application scope.

IPC Classes  ?

• A61K 9/50 - Microcapsules
• A61K 31/01 - Hydrocarbons
• A61P 3/06 - Antihyperlipidemics
• A61P 35/00 - Antineoplastic agents
• A61P 37/04 - Immunostimulants