Abrégé

The invention is based on the discovery of a novel compound with analgesic properties which could be used as a new tool for the treatment of pain disorders such as visceral pain. Thus, the invention relates to novel lipopeptide compound, derived from gamma-aminobutyric acid. The invention also relates to a lipopeptide compound according to the invention for the treatment of treating pain disorder, such as somatic pain and visceral pain.

Classes IPC  ?

• A61K 31/197 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino les groupes amino et carboxyle étant liés à la même chaîne carbone acyclique, p. ex. acide gamma-aminobutyrique [GABA], bêta-alanine, acide epsilon-aminocaproïque ou acide pantothénique
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]

Abrégé

The invention relates to a composition comprising at least two isolated bacteriophages that are aimed at Xylella fastidiosa (Xf), wherein each of said bacteriophages is capable of inhibiting the growth of said Xylella fastidiosa; and the first bacteriophage comprises a genome with a DNA sequence having at least 90% sequence identity to one of the sequences of one of the following groups of sequences i) to viii) and the second bacteriophage comprises a genome with a DNA sequence having at least 90% sequence identity to one of the sequences of another one of the following groups of sequences i) SEQ ID NO:1 to SEQ ID NO:3 ii) SEQ ID NO:4 to SEQ ID NO:6 iii) SEQ ID NO:7 iv) SEQ ID NO:8 to SEQ ID NO:9 v) SEQ ID NO:10 vi) SEQ ID NO:11 to SEQ ID NO:14 vii) SEQ ID NO:15 to SEQ ID NO:27 viii) SEQ ID NO:28 to SEQ ID NO:29.

Classes IPC  ?

• A01N 63/40 - Virus, p. ex. bactériophages
• A61K 35/76 - VirusParticules sous-viralesBactériophages

Abrégé

The present invention relates to a recombinant yeast cell genetically modified to express (i) at least one first bacterial antigen or an immunogenic fragment thereof intracellularly and (ii) at least one second bacterial antigen or an immunogenic fragment thereof on its extracellular surface, the at least one first bacterial antigen or an immunogenic fragment thereof being identical to or different from the at least one second bacterial antigen or an immunogenic fragment thereof. The present invention also concerns this recombinant yeast for use in vaccines and in treating or preventing bacteria-caused pathologies in livestock.

Classes IPC  ?

• A61K 39/02 - Antigènes bactériens
• A61K 39/108 - EscherichiaKlebsiella

Abrégé

The present invention relates to a fusion protein, to a nucleic acid coding for the protein, to a vector comprising the nucleic acid, to a host cell comprising the nucleic acid and/or vector, to a process for producing a fusion protein and to a process for bioconverting a substrate. The fusion protein of the present invention successively comprises (i) at least one polypeptide for targeting, and anchoring to, the bacterial membrane, (ii) at least one polypeptide corresponding to the hydrophilic domain of a plant P450 cytochrome, (iii) at least one binding polypeptide comprising at least 47 amino acids, and (iv) at least one polypeptide corresponding to the hydrophilic domain of a plant NADPH-dependent cytochrome P450 reductase.

Classes IPC  ?

• C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase
• C12N 15/62 - Séquences d'ADN codant pour des protéines de fusion
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli

Abrégé

Methods for preparing at least one glycolipid of formula (I): [Glc]n-xOy-R (I), with [Glc]n representing an osidic motif comprising 1-7 n glucosyl units; R representing a fatty acid radical with 4-24 carbon atoms; -xOy- symbolizing the attachment of the fatty acid radical to the osidic motif; the method comprising glucosylating a hydroxylated fatty acid of formula (II): R-yOH (II), where -yOH is a hydroxyl group attached to a carbon atom Cy; bringing the hydroxylated fatty acid of formula (II) into contact with at least one α-transglucosylase of the GH70 family in the presence of saccharose or a saccharose analogue.

Classes IPC  ?

• C12P 19/44 - Préparation d'O-glucosides, p. ex. glucosides
• A01N 25/04 - Dispersions ou gels
• A01N 25/30 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles caractérisés par les agents tensio-actifs
• A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
• C12N 9/10 - Transférases (2.)

Abrégé

The present invention relates to a method and a device for treating effluents comprising suspended matter (MES), nitrogen and phosphorus, preferably said effluents originate from an industrial process, and more preferably fish farming. The device comprises: - at least two rotary filters (7a-b); the mesh of the second rotary filter (7b) being finer than that of the first rotary filter (7a); the first rotary filter (7a) making it possible to filter the effluents in order to obtain a first retentate (e1a) and a first filtrate (e2a); the second rotary filter (7b) making it possible to filter the first filtrate (e2a) in order to obtain a second retentate (e1b) and a second filtrate (e2b); - a settling vessel (1) making it possible to give, from the first retentate (e1a) and the second retentate (e1b), a supernatant liquid (a1) and raw sludge (a2); - at least one tank (2) allowing flocculation by mixing the raw sludge (a2) and at least one flocculating agent in order to obtain a mixture (b1); - a filter press (3) for dehydrating the mixture (b1) in order to obtain a leachate (c1) and pressed sludge (c2); - a constructed wetland (4) comprising at least one vertical planted filter (5) and at least one horizontal planted filter (6) located downstream of the at least one vertical planted filter (5) and allowing the supernatant liquid (a1) and the leachate (c1) to be filtered to obtain treated juices (d1); and - at least one pump allowing the different solid and/or liquid matter to be transferred between the different elements of the device.

Classes IPC  ?

• C02F 9/00 - Traitement en plusieurs étapes de l'eau, des eaux résiduaires ou des eaux d'égout
• C02F 1/00 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout
• C02F 3/32 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout caractérisé par les animaux ou végétaux utilisés, p. ex. les algues
• C02F 11/121 - Traitement des boues d'égoutDispositifs à cet effet par déshydratation, séchage ou épaississement par déshydratation mécanique
• C02F 11/122 - Traitement des boues d'égoutDispositifs à cet effet par déshydratation, séchage ou épaississement par déshydratation mécanique à l’aide de filtres-presses

Abrégé

The invention relates to a method for the surface treatment of a solid substrate made of polysaccharide material, aimed at the hydrophobization of said surface. This method comprises the application, to this surface, of a reagent comprising at least one hydroxylated fatty acid and/or oligomer of this hydroxylated fatty acid and/or an ester of this hydroxylated fatty acid, then the heat treatment of the substrate under conditions causing esterification reactions to be carried out between carboxyl groups of the hydroxylated fatty acid, and hydroxyl groups of the polysaccharide and hydroxyl groups of the hydroxylated fatty acid.

Classes IPC  ?

• D21H 17/14 - Acides carboxyliquesLeurs dérivés
• D21H 21/16 - Agents de collage ou hydrophobes
• D21H 25/06 - Traitement physique, p. ex. chauffage ou irradiation du papier imprégné ou couché
• C08B 15/00 - Préparation d'autres dérivés cellulosiques ou de cellulose modifiée
• C08L 1/02 - CelluloseCellulose modifiée
• C08L 1/10 - Esters des acides organiques
• C08L 5/04 - Acide alginiqueSes dérivés

Abrégé

The present disclosure relates to a system for the production of proteins of interest composed of a non-sporulating bacterial strain of the genus Bacillus transformed with a plasmid containing an expression cassette of a protein of interest under the control of a strong promoter active in the stationary phase. The proteins of interest thus produced are present in a bacterial sacculus or anchored to the surface of the bacterium.

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• C07K 14/32 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries provenant de Bacillus (G)
• C12R 1/07 - Bacillus

Abrégé

The invention relates to a device for extracting ammonium ions (8) from a digestate resulting from a treatment of an enrichment liquid made of biodegradable material and comprising: - a bio-electrochemical treatment unit (12) receiving a first volume of digestate and a second volume of enrichment liquid, - a unit (40) for acquiring a value of at least one parameter representative of a value of at least one quality parameter of the digestate, and of a value of at least one quality parameter of the enrichment liquid, - a unit (44) for determining a value of a ratio of a mixture representative of an amount of biodegradable organic material relative to an amount of ammonium ions, - a unit (48) for determining a mixing ratio of the digestate and of the enrichment liquid depending on the value of the ratio characteristic of a mixture, - a control unit (52) configured to obtain it.

Classes IPC  ?

• C12P 3/00 - Préparation d'éléments ou de composés inorganiques à l'exception du dioxyde de carbone
• C02F 1/469 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par séparation électrochimique, p. ex. par électro-osmose, électrodialyse, électrophorèse
• C02F 3/28 - Procédés de digestion anaérobies
• C02F 9/00 - Traitement en plusieurs étapes de l'eau, des eaux résiduaires ou des eaux d'égout
• C02F 11/04 - Traitement anaérobieProduction du méthane par de tels procédés
• C05B 7/00 - Engrais à base essentielle d'orthophosphates alcalins ou d'ammonium
• C05F 17/50 - Procédés combinant au moins deux traitements différents biologiques ou biochimiques, p. ex. des traitements anaérobie et aérobie ou lombricompostage et traitement aérobie
• C12P 5/02 - Préparation des hydrocarbures acycliques
• C12M 1/107 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens pour recueillir les gaz de fermentation, p. ex. le méthane
• C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p. ex. fermenteurs commandés automatiquement
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie

Abrégé

Process for producing biogas from a digestate obtained from a digester, said process comprising a step of recovering the digestate at the outlet of a digester, a post-digester or a storage tank; a step of separating the digestate into a solid digestate and a liquid digestate; a step of introducing the solid digestate into at least one closed tank; a step of anaerobic digestion in the tank with neither heating nor mixing; and a step of recovering the biogas at the tank outlet.

Classes IPC  ?

• C12P 5/02 - Préparation des hydrocarbures acycliques
• C02F 11/04 - Traitement anaérobieProduction du méthane par de tels procédés
• C02F 11/12 - Traitement des boues d'égoutDispositifs à cet effet par déshydratation, séchage ou épaississement
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• C12M 1/107 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens pour recueillir les gaz de fermentation, p. ex. le méthane

Abrégé

Disclosed is a composition including yeast cells and at least one polyphenols having a molecular weight above 620 Da, the polyphenols are adsorbed and retained in the cytoplasm of the yeast cell. The present disclosure also concerns using the composition in cosmetic, dermatological, nutritional and/or pharmaceutical fields, as well as in winemaking to protect the wine against oxidation, therefore preserving the wine quality, color and aromas, and as an alternative to ageing of wine on lees.

Classes IPC  ?

• C12H 1/00 - Pasteurisation, stérilisation, conservation, purification, clarification ou vieillissement des boissons alcoolisées
• A61K 31/05 - Phénols
• A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
• A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
• A61K 31/7024 - Esters de saccharides
• A61K 36/064 - Saccharomycetales, p. ex. levure de boulanger
• A61K 36/45 - Ericaceae ou Vacciniaceae (famille de la bruyère ou de la myrtille), p. ex. myrtille, canneberge ou airelle
• A61K 36/87 - Vitaceae ou Ampelidaceae (famille de la vigne ou du raisin), p. ex. raisin, vitis rotumdifolia ou vigne vierge
• C12G 1/00 - Préparation du vin ou du vin mousseux
• C12H 1/22 - Vieillissement ou mûrissage par emmagasinage, p. ex. blondissement de la bière
• C12N 1/18 - Levure de boulangerieLevure de bière

Abrégé

A method of screening of at least one phenotype or biological process, for example, self-replicating ability of microbial cells, in a high throughput droplet micro- to milli-fluidic system, based on the use of a photoconvertible or a photoactivable fluorescent protein and artificial intelligence to allow automated imaging and selection.

Classes IPC  ?

• G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
• G01N 33/573 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour enzymes ou isoenzymes

Abrégé

The present invention relates to a superabsorbent polymer obtained by crosslinking at least one polycarboxylic acid. The invention also relates to a method for producing said superabsorbent polymer, and to its uses and applications, in particular in the field of agronomy for diffusing water or active substances.

Classes IPC  ?

• C08B 37/00 - Préparation des polysaccharides non prévus dans les groupes Leurs dérivés
• C08L 5/04 - Acide alginiqueSes dérivés
• C08J 3/075 - Gels macromoléculaires

Produits et services

Grains (seeds) and agricultural, horticultural and forestry products, neither prepared, nor transformed; fresh fruits and vegetables; natural plants and flowers; trees; shrubs; unprocessed cereal grains; fresh garden herbs; seedlings; vine plants; seeds (grains); seeds. Evaluations, assessments, research and reports in the scientific and technological fields provided by engineers; industrial research and analysis services provided by engineers; chemical analysis; technical project study; geological surveys; research with respect to environmental protection; biological research; bacteriological research; chemical research; geological research. Agricultural, horticultural and forestry services; tree surgery; landscape design; plant nursery services; selection, propagation and production of plants, namely, agricultural, horticultural and forestry services.

Abrégé

The present disclosure relates to a composition, in particular a biofertilizer or a probiotic, comprising a polymer matrix based on chitosan and anionic polysaccharides, in particular carrageenan, and microorganisms, and the method for preparing same.

Classes IPC  ?

• C05F 11/00 - Autres engrais organiques
• C05F 11/08 - Engrais organiques comportant l'addition de cultures bactériennes, de mycélium ou similaires

Abrégé

The invention relates to a cosmetic composition in the form of an emulsion, essentially free of surfactant(s), comprising: – an aqueous phase in a content of less than or equal to 45% by weight relative to the total weight of the composition; – a fatty phase comprising at least one oil; – stabilizing particles at the interface of the aqueous and fatty phases having a volume median size (Dv50) measured under wet conditions of from 1 to 80 µm, in a content of 0.05% to 30% by weight relative to the total weight of the composition.

Classes IPC  ?

• A61K 8/02 - Cosmétiques ou préparations similaires pour la toilette caractérisés par une forme physique particulière
• A61K 8/06 - Émulsions
• A61K 8/25 - SiliciumSes composés
• A61K 8/26 - AluminiumSes composés
• A61K 8/27 - ZincSes composés
• A61K 8/31 - Hydrocarbures
• A61K 8/34 - Alcools
• A61K 8/73 - Polysaccharides
• A61K 8/92 - Huiles, graisses ou ciresLeurs dérivés, p. ex. produits d'hydrogénation
• A61Q 1/00 - Préparations pour le maquillagePoudres corporellesPréparations pour le démaquillage
• A61Q 1/02 - Préparations contenant des colorants cutanés, p. ex. pigments
• A61Q 1/10 - Préparations contenant des colorants cutanés, p. ex. pigments pour les yeux, p. ex. eye-liner, mascara
• A61Q 5/00 - Préparations pour les soins des cheveux
• A61Q 19/00 - Préparations pour les soins de la peau

Abrégé

The present invention relates to compositions and methods for detecting muscle atrophy in a subject. The invention also provides novel biomarkers that allow in vitro or ex vivo detection of a loss of muscle mass in a subject. The invention also relates to the use of muscle atrophy as an indicator of the occurrence, or the risk of occurrence of a disease or a disorder in a subject. Furthermore, the invention relates to a kits and reagents for use in these methods.

Classes IPC  ?

• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique

Abrégé

The present invention relates to a novel regulator VipR able to regulate the expression of genes, and more specifically the expression of vip3A. It also relates to an expression system allowing the expression of a protein of interest through the VipR regulation. This expression system can be used to transform Bacillus strains.

Classes IPC  ?

• A01N 63/23 - B. thuringiensis
• A01P 7/04 - Insecticides
• C12N 9/22 - Ribonucléases
• C12N 15/75 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora pour Bacillus
• C12P 21/00 - Préparation de peptides ou de protéines

Abrégé

Organ transplantation remains the only definitive therapeutic solution for many pathologies, but the number of currently available grafts is largely insufficient. A new approach is proposed to quantitatively evaluate isolated organs by ultrasound, which enables to safely admit more isolated organs as grafts available for transplantation. The isolated organ (2) is received in an organ preservation container (3) made of ultrasound transparent material, and the isolated organ is imaged by an ultrasound imaging probe (6) through the container (3). The ultrasound image of the isolated organ is used to determine a quantitative index representing viability of the isolated organ.

Classes IPC  ?

• G01S 15/89 - Systèmes sonar, spécialement adaptés à des applications spécifiques pour la cartographie ou la représentation

Abrégé

A composition comprising an oil phase comprising notably a botanical extract and an oil in water emulsion comprising said composition. The composition can include one or more non-VOC bio-based solvents chosen from the group of esters of aliphatic monocarboxylic acids, two or more bio-based non-ionic surfactants, and an anti-foaming agent. It further relates to the use of such composition and emulsion as an insecticidal agent, in particular a larvicidal agent.

Classes IPC  ?

• A01N 65/24 - Lauraceae [famille du laurier], p. ex. laurier, avocat, sassafras, cannelle ou camphre
• A01N 25/04 - Dispersions ou gels
• A01N 25/30 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles caractérisés par les agents tensio-actifs
• A01N 43/08 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome des cycles à cinq chaînons avec l'oxygène comme hétéro-atome du cycle
• A01P 7/04 - Insecticides

Abrégé

A composition including an extract of Moricandia for the use thereof in the prevention and/or treatment of metabolic diseases related to impaired glucose tolerance and/or insulin resistance. Also a composition including an extract of Moricandia for the use thereof in the prevention of weight gain, in particular of body fat.

Classes IPC  ?

• A61K 36/31 - Brassicaceae ou Cruciferae (famille de la moutarde), p. ex. broccoli, chou ou chou-rave
• A23L 33/18 - PeptidesHydrolysats de protéines
• A61K 36/481 - Astragalus (astragalus cicer)
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques

Abrégé

The invention relates to an effluent collector (5, 5') for recovering effluents in the form of a suspension or solution at the outlet of a microfluidic device (3), comprising: - at least one absorbent paper (8, 8') for receiving the effluents, the absorbent paper being configured such that the received effluents migrate by capillarity into the absorbent paper and then dry, depositing solid objects or the dissolved molecules contained in the effluents on the fibres of the absorbent paper, - a rotating support (7, 7') extending along a longitudinal axis (X, X') and on which the absorbent paper is deposited, the rotating support being configured to move the absorbent paper relative to the discharge duct.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
• B01L 9/00 - Dispositifs de supportDispositifs de serrage

Abrégé

The present invention relates to the use of butyric acid or a butyric acid derivative, or one of their salts, to for the stimulation and/or disinhibition of plant immune responses, and to a method for treating a plant infection comprising administering butyric acid or a butyric acid derivative, or one of their salts, and optionally at least one plant defence stimulator (PDS). The present invention also relates to a phytosanitary kit comprising butyric acid or a butyric acid derivative, or one of their salts, for the stimulation and/or disinhibition of plant immune responses. The present invention is particularly suitable for use in the pharmaceutical, phytopharmaceutical, agricultural, agri-food and chemical fields.

Classes IPC  ?

• A01P 3/00 - Fongicides
• A01P 21/00 - Régulateurs de croissance des végétaux
• A01N 37/02 - Acides carboxyliques saturés ou leurs thio-analoguesLeurs dérivés
• A01N 63/30 - Champignons microscopiquesSubstances produites par des champignons microscopiques ou obtenues à partir de ceux-ci
• A01N 63/10 - Animaux Substances produites par des animaux ou obtenues à partir de ceux-ci
• A01N 43/16 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome des cycles à six chaînons avec l'oxygène comme hétéro-atome du cycle

Abrégé

The present invention relates to a viral strain derived from the human metapneumovirus (hMPV) strain having a genome sequence represented by sequence SEQ ID NO. 1, wherein said genome sequence comprises the following genetic modifications: (i) inactivation of the endogenous gene coding for the SH protein and/or for the G protein, and (ii) presence of an exogenous nucleotide sequence coding for at least one extracellular domain of the F protein of the human respiratory syncytial virus (hRSV), said domain being wild-type or mutated.

Classes IPC  ?

• A61K 39/155 - Paramyxoviridae, p. ex. virus de para-influenza
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61P 31/14 - Antiviraux pour le traitement des virus ARN
• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
• C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification

Abrégé

The present invention relates to a device including: a) means for measuring the reflectance or absorbance of light radiation by an area of the body or an extracorporeal element of an animal within a population of individuals; b) means suitable for receiving light-radiation reflectance or absorbance spectral data measured for each animal in the population of individuals; and c) data processing means suitable for determining, according to the received spectral data, a homeostatic emotional state for each animal, the animals being either in an unbalanced homeostatic emotional state or in a balanced homeostatic emotional state.

Classes IPC  ?

• A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

The present invention relates to a method for measuring methylglyoxal and/or glyoxal.

Classes IPC  ?

• G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres
• G01N 33/52 - Utilisation de composés ou de compositions pour des recherches colorimétriques, spectrophotométriques ou fluorométriques, p. ex. utilisation de bandes de papier indicateur

Abrégé

The invention relates to a sensor for measuring the viscoelastic properties of a material, the sensor comprising a rigid support (10) and a membrane (11) attached to the support (10), wherein the material is intended to come into contact with an outer surface (111) of the membrane (11). The sensor further comprises an active assembly (12) comprising at least one piezoelectric element bonded to the inner face of the membrane (11), wherein the active assembly (12) is configured to cause the membrane (11) to oscillate in a resonant mode. The invention also relates to a method for measuring the viscoelastic properties of a material and to a method for monitoring the coagulation of milk using such a sensor.

Classes IPC  ?

• G01N 29/028 - Analyse de fluides en mesurant l'impédance mécanique ou acoustique
• A01J 25/00 - Fabrication du fromage
• A23C 19/02 - Fabrication du caillé pour fromage
• G01H 13/00 - Mesure de la fréquence de résonance
• G01H 15/00 - Mesure de l'impédance mécanique ou acoustique
• G01N 29/036 - Analyse de fluides en mesurant la fréquence ou la résonance des ondes acoustiques
• G01N 29/22 - Recherche ou analyse des matériaux par l'emploi d'ondes ultrasonores, sonores ou infrasonoresVisualisation de l'intérieur d'objets par transmission d'ondes ultrasonores ou sonores à travers l'objet Détails
• G01N 29/24 - Sondes
• G01N 29/34 - Génération des ondes ultrasonores, sonores ou infrasonores
• G01N 33/04 - Produits laitiers
• G01N 11/00 - Recherche des propriétés d'écoulement des matériaux, p. ex. la viscosité, la plasticitéAnalyse des matériaux en déterminant les propriétés d'écoulement
• B06B 1/06 - Procédés ou appareils pour produire des vibrations mécaniques de fréquence infrasonore, sonore ou ultrasonore utilisant l'énergie électrique fonctionnant par effet piézo-électrique ou par électrostriction
• G01H 11/08 - Mesure des vibrations mécaniques ou des ondes ultrasonores, sonores ou infrasonores par détection des changements dans les propriétés électriques ou magnétiques par des moyens électriques utilisant des dispositifs piézo-électriques

Abrégé

A method of preparing multi-functionalized cellulose, including subjecting cellulose fibers concomitantly, in one-pot in an alkaline reaction medium, to a first functionalization step for grafting a first organic functional group on the cellulose and a second functionalization step for grafting a second organic functional group on the cellulose. The multi-functionalized cellulose fibers thus obtained, and containing at least a carboxyl function, are particularly suitable for being subjected to a nanofibrillation step to prepare multi-functionalized nanofibrillated cellulose.

Classes IPC  ?

• D01F 11/02 - Post-traitement chimique de filaments, ou similaires, faits par l’homme, pendant leur fabrication de cellulose, de dérivés de la cellulose, de protéines

Abrégé

A device (1) for simulating the behaviour of a mammalian limb, in particular that of an equine mammal, on the ground, includes an impactor (5) in contact with the ground and intended to compress the ground. The device has a mass (7) movable along a vertical rectilinear axis, a sensor (9) for measuring the vertical force applied to the impactor, and a device (10) for measuring the penetration of the impactor in the ground, under the effect of the movement of the mass (7). The device can include a vertical shaft connected to the impactor at its lower end, and also one or more stops placed on one or more vertical rods along which the mass moves, the one or more vertical rods being connected to the vertical shaft by one or more elastic members.

Classes IPC  ?

• G01N 3/48 - Recherche de la dureté ou de la dureté au rebondissement en effectuant des empreintes sous une charge impulsive par des dispositifs de pénétration, p. ex. chute d'une bille

Abrégé

The present invenon relates to a vaccine against influenza A viruses, said vaccine comprising HA protein and nanostructures bearing M2e, and its use for vaccinaon against avian influenza, especially in the veterinary field.

Classes IPC  ?

• A61K 39/145 - Orthomyxoviridae, p. ex. virus de l'influenza
• C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification
• A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus
• A61K 39/12 - Antigènes viraux
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

The invention relates to a two-phase liquid/solid refrigerant generator comprising an enclosure (2), a system for supplying pressurised gaseous fluid to the enclosure (2) which can be connected to a source for supplying pressurised gaseous fluid outside the enclosure, a fluid circulation circuit (6) housed at least partially inside the enclosure (2), and an inside volume (7) of the enclosure (2) extending inside the enclosure (2) around the fluid circulation circuit (6). The inlet (3) for supplying solidifiable aqueous composition and the outlet (4) for discharging two-phase liquid/solid refrigerant from the enclosure (2) are in fluid communication with the inside volume (7) of the enclosure (2) which forms the portion of the enclosure (2) for receiving the solidifiable aqueous composition. The or each fluid circulation circuit (6) is a coolant circulation circuit that can be connected to a cold production unit outside the enclosure in order to form a cold portion. The system for supplying pressurised gaseous fluid comprises at least one pressurised gaseous fluid outlet (10) which is arranged in the inside volume (7) of the enclosure (2) and is oriented towards the fluid circulation circuit (6).

Classes IPC  ?

• F25C 1/12 - Production de glace par congélation de l'eau des surfaces refroidies, p. ex. pour former des plaques
• F25C 5/04 - Appareils pour concasser, enlever ou recueillir la glace sans utiliser de scies

Abrégé

Desiccation tolerance is a protective process that allows mature seeds to tolerate cellular water contents below 10%. This process is acquired during seed maturation and is usually lost during imbibition, prior to germination, what enhances seed sensitivity to drought and heat. The present invention shows that it is however possible to maintain desiccation tolerance mechanisms after germination by activating iron absorption in mature seed before germination begins. As shown in the present results, modulation of iron content in seeds can be performed by several means : (i) by genetic means, either by reducing the expression of genes involved in chromatin condensation (e.g., by reducing the expression of the clf, h2az or swn genes), or by over-expressing proteins known to enhance iron absorption (e.g., the IRONMAN or bHLHs proteins), or (ii) by chemical means, for example by applying synthetic IRONMAN peptides or simply their synthetic conserved domains issued thereof directly onto the mature seed. Thanks to these treatments, the present invention advantageously allows germinating seeds to tolerate strong heat/dehydration stress during a phase of high sensitivity of the young seedling, what will have a major impact on agricultural yields and production timing.

Classes IPC  ?

• A01H 1/00 - Procédés de modification des génotypes
• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales

Abrégé

The present invention relates to a method for preparing insects or insect larvae rich in vitamin D, comprising raising insects or their larvae on an ergosterol-rich food substrate, for example fungi, in order to obtain ergosterol-rich insects or larvae and then exposing them to UV radiation. The present invention also relates to insects and insect larvae rich in vitamin D, and to compositions comprising same, in particular intended for human and/or animal food or for cosmetic use.

Classes IPC  ?

• A23K 10/30 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons
• A01K 67/033 - NÉCESSITÉS COURANTES DE LA VIE ÉLEVAGE; CHASSE; PIÉGEAGE; PÊCHE ÉLEVAGE; AVICULTURE; APICULTURE; PISCICULTURE; PÊCHE; OBTENTION D'ANIMAUX, NON PRÉVUE AILLEURS; NOUVELLES RACES D'ANIMAUX Élevage ou obtention d'animaux, non prévus ailleurs; Nouvelles races d'animaux Élevage ou obtention d'invertébrés; Nouvelles races d'invertébrés
• A23K 50/90 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les insectes, p. ex. pour les abeilles ou les vers à soie
• A23L 33/155 - Vitamines A ou D

Abrégé

The invention relates to a continuous process for the production of methionine or any methionine derivative chosen from its esters, its amides, its hydroxy and oxo analogs, the esters of said analogs and the amides of said analogs, from hydrogen sulfide or methanethiol, said process comprising the biological reduction of oxygen-containing sulfur compounds chosen from sulfates resulting from said process, to give hydrogen sulfide and/or methanethiol, said process comprising the following steps: providing a reactor with gas-permeable membrane(s), of MBfR (Membrane Biofilm Reactor) type, said membrane consisting of hollow fibers defining an inner lumen and an outer surface of the membrane, immersing the reactor membrane(s) in an aqueous liquid medium which comprises at least the oxygen-containing sulfur compound(s) and sulfate-reducing microorganisms (SRMs), so as to bring the outer surface or the lumen of the membrane into contact with said medium, injecting an electron-donating compound, in gaseous form, into the lumen of the membrane if its outer surface is in contact with the aqueous liquid medium, or in contact with the outer surface of the membrane if its lumen is in contact with the aqueous liquid medium, after sulfate reduction of the oxygen-containing sulfur compound(s) of the aqueous liquid medium by the SRMs, recovering the hydrogen sulfide and/or methanethiol from said aqueous liquid medium, reacting the hydrogen sulfide with methanol to obtain methanethiol and/or reacting the methanethiol with a precursor of methionine or of one of its derivatives in order to obtain, in one or more steps, a methionine salt or a salt of its derivatives, neutralizing said methionine salt or salt of one of its derivatives in the presence of sulfuric acid, and recovering the methionine or one of its derivatives and recycling the sulfates resulting from this neutralization into said aqueous liquid medium.

Classes IPC  ?

• C12P 3/00 - Préparation d'éléments ou de composés inorganiques à l'exception du dioxyde de carbone
• B01D 63/02 - Modules à fibres creuses
• C02F 3/34 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout caractérisé par les micro-organismes utilisés
• C12P 13/12 - MéthionineCystéineCystine
• B01D 61/24 - Dialyse
• C02F 1/66 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par neutralisationAjustage du pH
• C02F 3/12 - Procédés par les boues activées
• C02F 101/10 - Composés inorganiques
• C02F 101/30 - Composés organiques
• C02F 103/36 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter provenant de l'industrie chimique non prévue dans les groupes provenant de la fabrication de composés organiques

Abrégé

The present invention relates to an inactivated streptococcus, or a membrane fraction derived therefrom, the streptococcus being obtained from a streptococcus comprising a gene encoding a 16S ribosomal RNA, the gene comprising a nucleotide sequence consisting of the sequence SEQ ID NO: 1, for use in a therapeutic method for preventing and/or treating glucose intolerance and/or a disease associated with glucose intolerance in an individual in need thereof.

Classes IPC  ?

• A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques

Produits et services

Grains (seeds) and agricultural, horticultural and forestry products, neither prepared, nor transformed; fresh fruits and vegetables; natural plants and flowers; trees; shrubs; unprocessed cereal grains; fresh garden herbs; seedlings; vine plants; seeds (grains); seeds. Evaluations, assessments, research and reports in the scientific and technological fields provided by engineers; industrial research and analysis services provided by engineers; chemical analysis; technical project study; geological surveys; research with respect to environmental protection; biological research; bacteriological research; chemical research; geological research. Agricultural, horticultural and forestry services; tree surgery; landscape design; plant nursery services; selection, propagation and production of plants, namely, agricultural, horticultural and forestry services.

Abrégé

The present invention relates to a composition comprising bacteria of the strain L. casei SGC-K deposited at the National Collection of Cultures of Microorganisms in the Institut Pasteur, Mar. 8, 2021, under no. CNCM 1-5663. The invention also relates to the nutritional and therapeutic uses of said composition.

Classes IPC  ?

• A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
• A61P 3/04 - AnorexigènesMédicaments de l'obésité
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
• A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire

Abrégé

An adhesive composition including a calcium phosphate ceramic selected from tetracalcium phosphate and alpha-tricalcium phosphate, phosphorylated serine, polydopamine, and an aqueous solvent. Also, a kit for preparing the adhesive composition, which includes the calcium phosphate ceramic, phosphorylated serine, and polydopamine and a method for preparing the adhesive composition, as well as the uses thereof.

Classes IPC  ?

• A61L 24/00 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie

Abrégé

The present application relates to an in vitro method for the predictive diagnosis of a pathological condition from at least one biological sample taken from a subject and comprising microorganisms, the method comprising the identification and the relative abundance of said microorganisms present in the sample, the diagnosis being carried out using a pre-trained artificial intelligence model on the basis of a training set wherein the labelled data set comprises training subject profiles, each training subject profile comprising the identity and the relative abundance of all the microorganisms identified in at least one sample from said training subject without any preselection, wherein each training subject profile is labelled with the phenotype of the training subject from which it is derived.

Classes IPC  ?

• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
• C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries

Abrégé

The invention relates to a flame-retardant material composition for use in 3D printing, comprising or consisting of: - 30% to 60% by weight, relative to the total weight of the composition, of at least one polyolefin from renewable or petroleum-based resources; - 5% to 20% by weight, relative to the total weight of the composition, of at least one fibrous material; - 20% to 50% by weight, relative to the total weight of the composition, of at least one intumescent agent acting in the condensed phase; - 2.5% to 20% by weight, relative to the total weight of the composition, of at least one flame retardant acting in the gas phase; - 0.5% to 5% by weight, relative to the total weight of the composition, of at least one inorganic compound selected from zeolites or zeolitic materials, montmorillonites, vermiculites, silicates, aluminas, magnesium oxides, zinc oxides and a mixture of two or more thereof.

Classes IPC  ?

• C08K 3/22 - OxydesHydroxydes de métaux
• C08K 3/34 - Composés contenant du silicium
• C08K 5/52 - Phosphore lié à l'oxygène lié uniquement à l'oxygène
• C08K 5/5313 - Composés phosphiniques, p. ex. R2=P(:O)OR'
• C08K 7/06 - Éléments
• C08K 7/14 - Verre
• C08L 23/06 - Polyéthylène
• C08L 23/12 - Polypropylène

Abrégé

The present invention relates to a new method to promote malolactic fermentation (MLF) and/or growth of lactic acid bacteria in food products, in particular in red wines, using dried white wine lees.

Classes IPC  ?

• C12F 3/06 - Récupération des sous-produits à partir de la bière ou du vin
• C12G 1/08 - Enlèvement de la levure [dégorgeage]
• C12N 1/20 - BactériesLeurs milieux de culture
• C12P 7/56 - Acide lactique

Abrégé

The invention relates to a composition for use in the oral treatment of nemathelminthiasis, said composition comprising eleganolone and/or a bifurcanol-type linear diterpene, and a process for preparing a corresponding anthelmintic.

Classes IPC  ?

• A61K 31/121 - Cétones acycliques
• A61K 36/03 - Phaeophycota ou phaeophyta (algues brunes), p. ex. Fucus
• A61P 33/10 - Anthelmintiques
• A61K 31/045 - Composés hydroxylés, p. ex. alcoolsLeurs sels, p. ex. alcoolates

Abrégé

An in vitro or ex vivo method for producing and isolating a cell subpopulation including T cells specific for an antigen linked to a disease of interest, which includes steps of obtaining, from an isolated human biological sample, a population of mononuclear cells including T cells specific for the antigen with a high proliferative capacity, culturing these mononuclear cells in a suitable cell culture medium containing the antigen, and isolating T cells specific to the antigen which do not express the CD45RO and CD27 markers at their surface. The cell subpopulation thus obtained and isolated finds application in particular for the treatment of the disease of interest.

Classes IPC  ?

• A61K 35/17 - LymphocytesLymphocytes BLymphocytes TCellules tueuses naturellesLymphocytes activés par un interféron ou une cytokine
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus
• B01D 15/38 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction spécifique non couverte par un ou plusieurs des groupes , p. ex. chromatographie d'affinité, chromatographie d'échange par ligand ou chromatographie chirale
• C12N 5/0783 - Cellules TCellules NKProgéniteurs de cellules T ou NK

Abrégé

An optimised bio-electrochemical reactor for treating a liquid effluent containing a biodegradable organic pollution. At least one of the anode and cathode compartments of the reactor is a microbial biofilm compartment (12) including a multi-stage current collector immersed in an electrolyte comprising electroactive microorganisms. This current collector includes at least two stages, each defining a chamber acting as a container for a biocompatible granular support material and letting the fluid pass through. The effluent circulates inside the compartment (12) according to an X direction crossing the stages of the current collector. In operation, the support material (17) is in a fluidised state resulting either from the circulation of the effluent, or from the circulation of a fluidisation gas allowing optimising the active surface of the electrode and, consequently, the treatment of the effluent.

Classes IPC  ?

• C02F 3/00 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout
• C02F 1/461 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• C25B 1/02 - Hydrogène ou oxygène
• C25B 3/03 - Hydrocarbures acycliques ou cycliques
• C25B 3/07 - Composés contenant au moins un atome d’oxygène
• C25B 3/26 - Réduction du dioxyde de carbone
• C25B 9/13 - Cellules électrolytiques individuelles avec circulation d’un électrolyte
• H01M 8/16 - Éléments à combustible biochimique, c.-à-d. éléments dans lesquels des micro-organismes agissent comme catalyseurs

Abrégé

The present invention relates to the treatment of inflammatory bowel diseases with a kynurenine aminotransferase, a living recombinant bacterium which has been genetically modified to express and secrete said kynurenine aminotransferase, and/or a product of said kynurenine aminotransferase which is xanthurenic acid, a derivative thereof, or any pharmaceutically acceptable salt or solvate thereof.

Classes IPC  ?

• A61K 38/45 - Transférases (2)
• A61K 31/47 - QuinoléinesIsoquinoléines
• A61K 31/7084 - Composés ayant deux nucléosides ou nucléotides, p. ex. dinucléotide de la nicotinamide-adénine, dinucléotide de la flavine-adénine
• A61K 35/74 - Bactéries
• A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]

Abrégé

The invention relates to three bacterial strains belonging to the Enterococcus genus, to a composition comprising at least one of said strains and to the beneficial uses thereof, in particular as a medicament in the treatment and/or prevention of respiratory diseases.

Classes IPC  ?

• A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61P 11/06 - Antiasthmatiques
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]

Abrégé

The invention relates to a method for reconstructing a mass spectrum, the method comprising the following steps: - acquiring (1010) a plurality of mass spectra measured on an ionised sample; - determining (1020) a plurality of series of abundance values for the ionised sample; - arranging (1030) series of abundance values in pairs comprising a first series and a second series; - for each pair, calculating (1040) a match score between the first series and the second series in order to provide a match score map between all the pairs of the series; - determining (1060), according to a mass-to-charge ratio, at least one precursor ion and fragment ions that are associated with each precursor ion by applying a clustering method to the score map; - reconstructing (1070) a mass spectrum for each precursor ion and for each of the associated fragment ions using the match score map.

Classes IPC  ?

• H01J 49/00 - Spectromètres pour particules ou tubes séparateurs de particules

Abrégé

The present invention relates to genetically modified bacteria capable of inducibly expressing a nucleic acid sequence of interest, genetic constructs, vectors and uses thereof.

Classes IPC  ?

• C12N 15/74 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora
• C12P 21/00 - Préparation de peptides ou de protéines

Abrégé

22 O.

Classes IPC  ?

• C05C 1/00 - Engrais de nitrate d'ammonium
• C05F 11/00 - Autres engrais organiques
• C05G 3/90 - Mélanges d'un ou plusieurs engrais avec des additifs n'ayant pas une activité spécifique d'engrais pour influer sur la nitrification des composés d’ammonium ou de l’urée dans le sol

Abrégé

LdlrLdlrLdlr/" females; 2) potently decreases the size of aortic atherosclerotic lesions. These preliminary data support the hypothesis of a beneficial role of LIPC E97G towards the development of atherosclerosis and reinforce the need for further studies. Interestingly, they also open the prospect of new therapeutic solutions in familial hypercholesterolemia (EH) patients with partial/total EDER deficiency. The present invention relates to a method for treating hypercholesterolemia, including homozygous and heterozygous EH, and related ASCVD in a subject in need thereof comprising administering a therapeutically effective amount of a LIPC variant to said subject in need thereof.

Classes IPC  ?

• A61K 38/46 - Hydrolases (3)
• A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61P 3/06 - Antihyperlipémiants
• A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
• C12N 15/86 - Vecteurs viraux

Abrégé

The invention relates to a method for removing uremic toxins bound to a protein from the blood of a patient in need thereof. The method comprises the introduction in the blood of a displacer substance chosen from (C6-C12)-fatty acids, salts of (C6-C12)-fatty acids, a precursor of said (C6-C12)-fatty acids, or mixtures thereof. The displacer substance replaces the uremic toxins bound to the protein, thereby releasing unbound uremic toxins in the blood. The unbound uremic toxins are then removed from the blood by any method of dialysis. The method according to the invention involves low concentrations of displacer substance and is effective at plasma concentrations comprised in the range of from 0.5 to 3 mM.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes
• A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
• A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c.-à-d. hémofiltration, diafiltration
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p. ex. adaptation de la température, irradiation

Abrégé

The invention relates to a method for removing uremic toxins bound to a protein from the blood of a patient in need thereof. The method comprises the introduction in the blood of a displacer substance chosen from (C6-C12)-fatty acids, salts of (C6-C12)-fatty acids, a precursor of said (C6-C12)-fatty acids, or mixtures thereof. The displacer substance replaces the uremic toxins bound to the protein, thereby releasing unbound uremic toxins in the blood. The unbound uremic toxins are then removed from the blood by any method of dialysis. The method according to the invention involves low concentrations of displacer substance and is effective at plasma concentrations comprised in the range of from 1 µM to 3 mM.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes
• A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
• A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c.-à-d. hémofiltration, diafiltration
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p. ex. adaptation de la température, irradiation
• A61K 31/19 - Acides carboxyliques, p. ex. acide valproïque
• A61K 31/20 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p. ex. acides stéarique, palmitique ou arachidique

Produits et services

Leading and coordinating research teams in the context of scientific research, namely arranging of study and information exchange workshops; all the aforesaid services, in relation to the following fields: Sustainable agriculture and food, forests and balanced management of natural resources. Conducting and coordination of scientific research works, planning of scientific research projects and Management of scientific research projects, Scientific monitoring services for research needs; all the foregoing, in relation to the following fields: Sustainable agriculture and food, forests and balanced management of natural resources.

Produits et services

Leading and coordinating research teams in the context of scientific research, namely arranging of study and information exchange workshops; all the aforesaid services, in relation to the following fields: Sustainable agriculture and food, forests and balanced management of natural resources. Conducting and coordination of scientific research works, planning of scientific research projects and Management of scientific research projects, Scientific monitoring services for research needs; all the foregoing, in relation to the following fields: Sustainable agriculture and food, forests and balanced management of natural resources.

Abrégé

The application relates to an emulsifying agent comprising a lignin fraction and its use to prepare emulsions. The application also relates to cosmetic products comprising such an emulsifying agent and methods for preparing the same.

Classes IPC  ?

• A61K 8/06 - Émulsions
• A61K 8/72 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques macromoléculaires
• A61Q 1/02 - Préparations contenant des colorants cutanés, p. ex. pigments
• A61K 8/34 - Alcools
• A61K 8/37 - Esters d'acides carboxyliques
• C08L 97/00 - Compositions contenant des matières contenant de la lignine
• C07G 1/00 - Dérivés de lignine à bas poids moléculaire

Abrégé

The present invention relates to the association of at least one bacterial strain of the species Enterococcus faecalis and an anti-inflammatory agent, a composition comprising same, and the uses thereof as a medicament, in particular for preventing and/or treating respiratory diseases.

Classes IPC  ?

• A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques
• A61K 31/58 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes contenant des hétérocycles, p. ex. danazol, stanozolol, pancuronium ou digitogénine
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]

Abrégé

The present invention proposes a method for manufacture of an endoprosthesis, in particular a vascular endoprosthesis, comprising the 3D printing (100) of a hollow membrane made of thermoplastic elastomer, and the fastening (200) of a collapsible metal framework to the hollow membrane in order to form a membrane-framework assembly. The fastening comprises (i) the 3D printing (201) of an additional membrane made of thermoplastic elastomer, the arranging (202) of the collapsible metal framework between the hollow membrane and the additional membrane in order to obtain an assembly, the immersion soaking (204) of the assembly in an organic solvent in order to obtain the membrane-framework assembly, and the drying (205) of the membrane-framework assembly; or (ii) the arranging (212) of the collapsible metal framework on the hollow membrane in order to obtain an assembly, and the dip coating (214) in a solution in an organic solvent, and then the drying (215) of the assembly.

Classes IPC  ?

• A61F 2/07 - Endoprothèses déployables couvertes

Abrégé

The invention relates to a chemically-modified microorganism selected from bacteria and yeasts, which contains a superoxide dismutase mimic inorganic complex, in particular a mimic of human manganese superoxide dismutase. This microorganism is particularly useful for treating an inflammatory disease, in particular an inflammatory bowel disease, by oral administration.

Classes IPC  ?

• A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
• A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques

Abrégé

The invention relates to a method for heat transfer between a granular material (14) capable of forming a moving bed and a fluid (15), the method comprising filling a cylindrical chamber (2) with the granular material (14), the longitudinal axis (XX') of which cylindrical chamber extends horizontally in its configuration of use, supplying fluid to the chamber (2) via at least one cylindrical fluid-receiving tube (3) arranged at least partially inside the chamber (2), and rotating the chamber (2) about an axis coincident with the longitudinal axis (XX') of the chamber (2). The tube (3) is coaxial with the longitudinal axis (XX') of the chamber (2) and leads, at each of its ends, out of the chamber (2) so as to be able to be connected to a fluid circulation circuit (5), and the filling of the chamber (2) with the granular material (14) involves filling up to a filling height (H) comprised within the height range defined by the formula: R + a x R1, where R corresponds to the inner radius of the cylindrical chamber (2) and R1 corresponds to the inner radius of the cylindrical fluid-receiving tube (3), and where a is between 0 and 1.

Classes IPC  ?

• F28D 11/02 - Appareils échangeurs de chaleur utilisant des canalisations mobiles le mouvement étant rotatif, p. ex. effectué par un tambour ou un cylindre
• F28D 20/00 - Appareils ou ensembles fonctionnels d'accumulation de chaleur en généralAppareils échangeurs de chaleur de régénération non couverts par les groupes ou
• F28D 13/00 - Appareils échangeurs de chaleur utilisant un lit fluidisé

Abrégé

The present invention relates to an improved method for the preparation of 2,4- dihydroxybutyrate from a carbon source via homoserine comprising a two steps pathway: - a first step of conversion of the primary amino group of homoserine to a carbonyl group to obtain 2-oxo-4-hydroxybutyrate catalysed by an enzyme having homoserine transaminase activity as defined by E.C. 2.6.1.1 or E.C. 2.6.1.42 or E.C. 2.6.1.57 and - a second step of reduction of the obtained 2-oxo-4-hydroxybutyrate (OHB) to 2,4-dihydroxybutyrate catalysed by an enzyme having OHB reductase activity, the enzyme having OHB reductase activity is lactate dehydrogenase as defined by E.C.1.1.1.27 or E.C.1.1.1.28, or malate dehydrogenase as defined by E.C.1.1.1.37, E.C.1.1.1.82 or E.C.1.1.1.299, and wherein at least one enzyme having aldolase activity as defined by E.C.4.1.2.28 is inactivated to prevent OHB degradation.

Classes IPC  ?

• C12P 7/52 - Acide propioniqueAcides butyriques
• C12N 9/04 - Oxydoréductases (1.), p. ex. luciférase agissant sur des groupes CHOH comme donneurs, p. ex. oxydase de glucose, déshydrogénase lactique (1.1)
• C12N 9/10 - Transférases (2.)
• C12N 9/88 - Lyases (4.)

Abrégé

The present invention relates to the use of micropeptides (peptides encoded by microRNAs or "miPEPs") for inhibiting the growth of parasitic plants, in particular that of broomrapes. The present invention also relates to the compositions and methods for inhibiting the growth of parasitic plants, in particular that of broomrapes.

Classes IPC  ?

• C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
• A01N 25/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles
• C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression
• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• A01N 37/46 - Dérivés N-acylés
• A01P 13/02 - HerbicidesAlgicides sélectifs
• C12Q 1/6895 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les plantes, les champignons ou les algues

Abrégé

A mill (1) comprising at least a frame (2), grinding bodies and, carried by said frame (2), a grinding chamber (4) of longitudinal axis (XX'), a stirrer comprising a rotary finger-bearing shaft coaxial with the longitudinal axis (XX') of the grinding chamber (4), a motor with a rotatable part that can be coupled to the finger-bearing shaft, and a system for heating the grinding chamber (4). The grinding chamber (4) comprises at least a first (11), a second (12) and a third closable inlet (13) and an outlet (14). The grinding chamber (4), the stirrer and at least the rotatable part of the motor form an assembly mounted so as to be able to rotate about an axis (ZZ') orthogonal to the longitudinal axis (XX') of the grinding chamber (4) in order to move the grinding chamber (4) between a first position, in which the finger-bearing shaft extends horizontally, and a second position, in which the finger-bearing shaft extends vertically, and the fingers of the finger-bearing shaft are removably mounted on the finger-bearing shaft in order to be able to vary the number and/or position of the fingers.

Classes IPC  ?

• B02C 17/16 - Appareils comportant des agitateurs placés dans une cuve fixe entraînant le contenu en mouvement
• B02C 17/18 - Désagrégation au tonneau, c.-à-d. par des appareils constitués par une cuve où les produits à désagréger sont chargés, avec ou sans éléments particuliers de désagrégation tels que billes ou boulets Parties constitutives

Abrégé

The invention relates to genetically modified bacteria comprising an invasive orthogonal expression system and to the use thereof for producing at least one protein of interest. The invention also relates to polynucleotides, vectors and kits for the expression of at least one protein of interest.

Classes IPC  ?

• C07K 14/195 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries
• C07K 14/245 - Escherichia (G)
• C07K 14/32 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries provenant de Bacillus (G)
• C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression
• C12N 15/75 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora pour Bacillus
• C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p. ex. glutathion
• C12R 1/01 - Bactéries ou actinomycètes
• C12R 1/125 - Bacillus subtilis
• C12R 1/19 - Escherichia coli

Abrégé

There is provided a method for enhancing the photoresistance of a fluorescent protein when used in fluorescence microscopy of a sample containing several molecules of the fluorescent protein according to a fluorescence microscopy technique. The method includes illuminating at least partially the sample with an exciting light beam and illuminating at least partially the same region of the sample with an enhancing light beam. There is also provided a fluorescence microscopy system suitable to implement the above method.

Classes IPC  ?

• G01N 21/64 - FluorescencePhosphorescence
• G02B 21/06 - Moyens pour éclairer un échantillon
• G02B 21/16 - Microscopes adaptés pour éclairage ultraviolet

Abrégé

Metarhizium robertsiiMetarhizium robertsiiMetarhizium robertsii to a bed bug habitat.

Classes IPC  ?

• A01N 63/30 - Champignons microscopiquesSubstances produites par des champignons microscopiques ou obtenues à partir de ceux-ci
• A01P 7/04 - Insecticides
• C12N 1/14 - ChampignonsLeurs milieux de culture

Abrégé

The invention relates to a method for determining at least one characteristic of the soil in a geographical zone, the method being implemented by computer and comprising the steps of: detecting, in at least one georeferenced image (8) associated with the geographical zone, at least one symbol (10) representative of a pedological data measurement point, and an associated unique identifier; for each symbol (10) detected: calculating the geographical coordinates of the corresponding measurement point, from the position of said symbol (10) in the image and the georeferencing of the image; from the corresponding unique identifier, identifying, in a pedological database associated with the geographical zone, the pedological data corresponding to the respective measurement point.

Classes IPC  ?

• G01C 11/04 - Restitution des photos
• G01N 33/24 - Matériaux de la terre

Abrégé

The invention relates to a preparation for pharmaceutical, veterinary or food use containing at least one alga and/or at least one extract from an alga belonging to the Fucales order for use as an anthelmintic in the oral treatment of helminthiasis caused by organisms in the Rhabditina and/or Spirurina suborder which are resistant to anthelmintics belonging to the groups of macrocyclic lactones, benzimidazoles, imidazothiazoles and/or tetrahydropyrimidines, to the use of such a preparation to treat, control and prevent helminth infections in a warm-blooded animal or a human being, and to a method for obtaining such a preparation.

Classes IPC  ?

• A61K 36/03 - Phaeophycota ou phaeophyta (algues brunes), p. ex. Fucus
• A61P 33/10 - Anthelmintiques

Abrégé

The present invention relates to a novel glycoside hydrolase enzyme, in particular to a novel fucanase, to nucleic acid sequences encoding this enzyme, to a vector comprising said coding sequence, to a method for producing this glycoside hydrolase enzyme, and also to a method for degrading sulfated fucans using this enzyme and to the polysaccharides obtained. The present invention is of use mainly in the field of agriculture, animal and human nutrition, cosmetics, pharmacy, laboratory research, in particular for the production of molecules or for the fine analysis of the structure and compositions of sulfated fucan polysaccharides of varied nature and origin.

Classes IPC  ?

• C12N 9/24 - Hydrolases (3.) agissant sur les composés glycosyliques (3.2)
• C12P 19/04 - Polysaccharides, c.-à-d. composés contenant plus de cinq radicaux saccharide reliés entre eux par des liaisons glucosidiques
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
• C12P 19/02 - Monosaccharides
• C12P 19/14 - Préparation de composés contenant des radicaux saccharide préparés par action d'une carbohydrase, p. ex. par action de l'alpha-amylase

Abrégé

paratuberculosis (Map) S-type strain, as well as derivatives and conjugates thereof. The invention also concerns the use of these antigens in different methods and tests for detecting Map infection, especially by detecting humoral response and cell mediated response of infected animals. The invention is also directed to a genetic signature of Map and a mass spectrometry and NMR spectroscopy signature of Map presence or infection.

Classes IPC  ?

• C07K 5/087 - Tripeptides la chaîne latérale du premier amino-acide contenant des carbocycles, p. ex. Phe, Tyr
• A61K 39/04 - Mycobacterium, p. ex. Mycobacterium tuberculosis
• A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
• A61K 47/60 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique macromoléculaire, p. ex. une molécule oligomérique, polymérique ou dendrimérique obtenu par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyurées ou polyuréthanes le composé organique macromoléculaire étant un oligomère, un polymère ou un dendrimère de polyoxyalkylène, p. ex. PEG, PPG, PEO ou polyglycérol
• C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
• C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
• G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus

Produits et services

ornamental trees, excluding the following goods: Fruit trees.

Abrégé

A masterbatch including at least one thermoplastic polymer and at least one ionene polymer as well as to the production method thereof. Further, the use of such a masterbatch for producing an article having bacteriostatic or bactericidal properties.

Classes IPC  ?

• C08L 23/06 - Polyéthylène
• C08J 5/18 - Fabrication de bandes ou de feuilles
• C08L 79/02 - Polyamines

Abrégé

The present invention in general relates to enzymes with a polysaccharide oxidase activity. In particular, the invention relates to the field of second-generation ethanol production by oxidation and enzymatic hydrolysis of materials containing polysaccharides, in particular lignocellulosic biomass. The invention further relates to the field of celluloses, and to method for producing cellulose fibres and defibrillating cellulose substrates.

Classes IPC  ?

• C12P 7/10 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique préparé comme sous-produit, ou préparé à partir d'un substrat constitué par des déchets ou par des matières cellulosiques d'un substrat constitué par des matières cellulosiques
• C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase

Abrégé

The present invention relates to a new antisense oligonucleotide, a pharmaceutical composition comprising it and their use for preventing or treating infection by coronavirus, especially by SARS-CoV-2 virus which causes the infection disease COVID-19.

Classes IPC  ?

• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
• A61P 31/14 - Antiviraux pour le traitement des virus ARN

Abrégé

The present invention relates to the use of a sequence chosen among Seq ID No 3, Seq ID No 1, Seq ID No 2, Seq ID No 4, Seq ID No 5, Seq ID No 6, Seq ID No 7, Seq ID No 8, and functional variants thereof, as an odorant binding protein (OBP).

Classes IPC  ?

• C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet

Abrégé

The present disclosure relates to a new gene involved in sex determination in Cucurbitaceae. The loss of function of the protein encoded by this gene induces a transformation of female flowers to hermaphrodite flowers and fruits with non-altered shape. The present disclosure is thus directed to Cucurbitaceae plant modified so that expression and/or function of the protein encoded by said new gene is abolished; the plant having hermaphrodite flowers instead of female flowers and preferably fruits with a non-altered shape.

Classes IPC  ?

• A01H 1/00 - Procédés de modification des génotypes
• A01H 1/06 - Procédés de mutation, p. ex. traitements par produits chimiques ou irradiations
• C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux

Produits et services

Probes for scientific use; scientific apparatus and instruments; laboratory apparatus for detecting genetic sequences; diagnostic apparatus, not for medical use. Probes for medical use; DNA testing apparatus for medical use; genetic testing apparatus for medical use; medical apparatus and instruments. Development of probes for biotechnological applications; scientific services; research in biotechnology; advice in biotechnology; research and development in the field of biotechnology; evaluation, assessment and research in scientific and technological fields carried out by researchers; DNA screening services for scientific research; research with respect to DNA sequencing technology; DNA analysis services for scientific research purposes; genetic research; genetic mapping for scientific use; scientific research in the field of genetics. Medical services; medical analyses; DNA analysis for medical purposes; medical and health services relating to DNA, genetics and genetic testing; genetic analysis for medical use; genetic consultation.

Abrégé

Disclosed is a method of additive manufacturing by hot-extrusion, which method of additive manufacturing includes the following successive steps: a providing step, wherein a printable composition is provided, the printable composition including an aqueous printing matrix, in which non-gelatinized starch granules are dispersed, wherein the non-gelatinized starch granules are in a non-gelled state and have a gelatinization temperature below 70° C.; and a printing step, wherein the printable composition is subjected to a heat treatment and is deposited layer by layer. During the printing step, the printable composition is subjected to a succession of two different heating temperatures: a storage heating temperature, lower than the gelatinization temperature, in order to heat the printable composition without gelatinizing the non-gelatinized starch granules, and a printing heating temperature, higher than the gelatinization temperature, in order to gelatinize the non-gelatinized starch granules in the layers.

Classes IPC  ?

• A23P 20/20 - Fabrication de produits alimentaires feuilletés, multicouches, fourrés ou à corps creux, p. ex. par enveloppement dans des feuilles de pâte comestible préformée ou dans des récipients alimentaires comestibles
• A23L 5/10 - Procédés généraux de cuisson des aliments, p. ex. par rôtissage ou friture
• A23P 20/25 - Remplissage ou fourrage de produits alimentaires enrobés, p. ex. combiné avec l’enrobage ou la formation de creux
• A23P 30/20 - Extrusion
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 30/00 - Appareils pour la fabrication additiveLeurs parties constitutives ou accessoires à cet effet
• B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
• B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive

Abrégé

The present invention relates to the field of anticancer treatment, more specifically to methods for ex vivo determining whether a patient with hematological malignancies is likely to benefit from allogeneic hematopoietic stem cell transplantation (allo-HSCT) by analyzing the gut microbiota in a fecal sample from said patient; the present invention also relates to treatments aimed to reduce the risk of relapse following allo-HSCT.

Classes IPC  ?

• C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
• C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
• A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
• A23L 33/00 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement
• A61P 31/04 - Agents antibactériens
• A61K 35/74 - Bactéries
• C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification

Abrégé

The present invention relates to an extract of algae of the genus Ulva and the use thereof in human and animal nutrition for the treatment of inflammation, preferably inflammation associated with a metabolic syndrome, and for the treatment of cognitive and/or emotional disorders caused by a metabolic syndrome. The present invention also relates to dietary supplements and food compositions comprising an extract of algae of the genus Ulva.

Classes IPC  ?

• A61K 36/05 - Chlorophycota ou chlorophyta (algues vertes), p. ex. Chlorella
• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
• A61P 3/04 - AnorexigènesMédicaments de l'obésité
• A61P 3/06 - Antihyperlipémiants
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
• A61P 25/22 - Anxiolytiques
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Produits et services

Pharmaceutical products; medical and veterinary preparations; diagnostic preparations, reagents and indicators for medical use; diagnostic testing products and materials for medical use; diagnostic biomarking reagents for medical use; products for destroying vermin; fungicides; herbicides; anti-parasitic products; chemical preparation for pharmaceutical use, vaccines; all these goods relating to zoonotic diseases. Advertising; commercial business management; commercial administration; dissemination of advertising material (leaflets, prospectuses, printed matter, samples); newspaper subscription services (for third parties); business management and organization consultancy; computerized file management services; organization of exhibitions for commercial or advertising purposes; online advertising on a computer network; rental of advertising time on all communication media; publication of advertising texts; rental of advertising space; advice regarding communication (public relations); company audits (commercial analyses); commercial intermediation services; research, collection, transcription, processing, analysis, compilation, management, provision and updating of data; assistance and advice with respect to data processing; all these services rendered in the field of health. Education; training; providing information with respect to education; vocational retraining; publication of books; book lending; providing non-downloadable films via video-on-demand services; motion picture production; organization of competitions (education or entertainment); organizing and conducting of colloquiums, conferences, congresses, participatory workshops; organization of exhibitions for cultural or educational purposes; electronic publication of books and journals online; all these services rendered in the field of health. Technical evaluations concerning design (engineers' services); scientific and technical research; biological, clinical and medical research; scientific research for medical purposes in the field of infectious diseases; socio-ecological, epidemiological and microbiological studies; development of disease diagnosis methods; design, development and maintenance of computers for third parties; design, development, installation, maintenance, rental and updating of software; research and development of new products for third parties; conducting of technical project studies; programming for computers; computer system analysis; computer system design; consultant services with respect to computer hardware design and development; Software as a Service (SaaS); cloud computing; advice regarding information technology; server hosting; electronic data storage; all these services rendered in the field of health. Medical screening; medical assistance, veterinary services; medical information; medical treatment service; medical analysis; carrying out disease diagnoses; medical testing services relating to disease diagnosis and treatment; all these services relating to zoonotic diseases.

Abrégé

The invention relates to a method for marking a material, for example for purposes of authentication and/or traceability of said material, notably batches generated. The said marking method comprises: - a step of supplying a marking composition chosen among molecular tags, and - a step of incorporating said marking composition into said material. And, according to the invention, said marking composition comprises particles, advantageously remaining intact after incorporation in said material, which comprise: - a homogeneous porous matrix which comprises a plurality of pores, - an information support added to said homogeneous porous matrix, wherein said information support consists of a polymer comprising an information sequence, and - a particle surface having a coating with at least one fluidizing agent, suitable for promoting uniform dispersion of said particles within said material.

Classes IPC  ?

• C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites

Abrégé

The invention relates to a cell-based method of identifying one or more enzyme variants that produces an increased level of a ketone. The method of the invention involves incubating cells comprising a vector encoding one or more enzyme variants with para-methox-2-amino benzamidoxime, measuring the signal emitted and comparing the signal to cells comprising a vector encoding a reference enzyme. A system for identifying one or more enzyme variants, and genetically engineered enzyme variants that produce increased levels of a ketone are also disclosed.

Classes IPC  ?

• C12Q 1/26 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une oxydoréductase
• G01N 21/64 - FluorescencePhosphorescence
• C12N 15/53 - Oxydoréductases (1)

Abrégé

The present invention relates to a spent grain juice obtained from the extraction of brewer's draff and the use thereof for the biosynthesis of molecules of interest, for example pigments such as violacein and derivatives thereof.

Classes IPC  ?

• C12P 17/16 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle contenant plusieurs hétérocycles
• A01N 63/32 - Levure
• C12N 1/16 - LevuresLeurs milieux de culture
• C12P 19/14 - Préparation de composés contenant des radicaux saccharide préparés par action d'une carbohydrase, p. ex. par action de l'alpha-amylase
• C12P 23/00 - Préparation de composés contenant un cycle cyclohexène comportant une chaîne latérale non saturée d'au moins dix atomes de carbone liés par des doubles liaisons conjuguées, p. ex. carotènes

Abrégé

Limosilactobacillus mucosae Limosilactobacillus mucosae , or a lysate or culture supernatant thereof, for use in the prevention and/or treatment of disorders requiring an increase in GLP-1 production in a subject in need of GLP-1, the disorders being selected from (i) a disorder related to dysregulation of insulin sensitivity and/or blood glucose concentration and (ii) loss of muscle mass and/or muscle function.

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques
• C12R 1/01 - Bactéries ou actinomycètes
• C12R 1/225 - Lactobacillus
• C12R 1/23 - Lactobacillus acidophilus
• C12R 1/245 - Lactobacillus casei
• C12R 1/46 - Streptococcus
• C12R 1/85 - Saccharomyces
• C12R 1/865 - Saccharomyces cerevisiae

Abrégé

The present invention concerns a controlled gene therapy of ocular diseases. This technology can be used in gene therapy protocols and avoids the side effects resulting from a continuous and uncontrolled expression of a transgene.

Classes IPC  ?

• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• C12N 15/86 - Vecteurs viraux

Abrégé

The instant invention relates to haploid inducer plant lines and methods for producing these plant lines. The invention further relates to methods for producing a haploid plant, and to the use of such haploid plant for generating a doubled haploid plant.

Classes IPC  ?

• A01H 5/10 - Graines
• A01H 6/46 - Gramineae ou Poaceae, p. ex. ivraie, riz, blé ou maïs

Abrégé

The present invention relates to the field of medicine. It more particularly relates to new anti-soluble CD146 (sCD146) protein antibodies, in particular multispecific antibodies comprising antigen binding regions that specifically bind sCD146 and VEGF proteins, to nucleic acids and vectors encoding and/or expressing such antibodies, and to cells and compositions comprising such product(s), as well as to uses thereof, typically in the treatment of cancer, preferably cancer resistant to treatments involving an anti-VEGF antibody. The invention also relates to uses of anti-sCD146 antibodies for predicting or monitoring the response of a subject to a treatment of cancer involving an anti-VEGF agent, and to related methods.

Classes IPC  ?

• C07K 16/22 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des facteurs de croissance
• C07K 16/30 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire provenant de cellules de tumeurs
• A61P 35/00 - Agents anticancéreux

Abrégé

The invention relates to a device for spraying ozonated water in an agricultural environment, the device comprising a collar defining a dispensing opening (4) for dispensing both water and ozone together, the water being sprayed by a nozzle (10) set back from the opening, the nozzle being supplied from a tank (7) installed with the device, the ozone gas being dispensed via a gas inlet (22) connected to a device for producing and/or storing gas (9, 13) which is also installed with the device, the gas inlet also being set back in the collar such that the collar defines a chamber (28, 29) for confining the ozone gas emitted around the sprayed liquid in order to allow the sprayed liquid to be enriched with dissolved ozone.

Classes IPC  ?

• B05B 7/04 - Pistolets pulvérisateursAppareillages pour l'évacuation avec des dispositifs permettant le mélange de liquides ou d'autres matériaux fluides avant l'évacuation
• B05B 1/34 - Buses, têtes de pulvérisation ou autres dispositifs de sortie, avec ou sans dispositifs auxiliaires tels que valves, moyens de chauffage agencés pour influencer la forme de l'écoulement du liquide ou d'autre matériau fluide, p. ex. pour produire une turbulence
• A61L 2/22 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances à phases, p. ex. des fumées, des aérosols
• A61L 9/14 - Désinfection, stérilisation ou désodorisation de l'air utilisant des substances vaporisées ou pulvérisées
• B05B 1/04 - Buses, têtes de pulvérisation ou autres dispositifs de sortie, avec ou sans dispositifs auxiliaires tels que valves, moyens de chauffage agencés pour produire un jet, un pulvérisat ou tout autre écoulement de forme ou de nature particulière, p. ex. sous forme de gouttes individuelles de forme plane, p. ex. en forme d'éventail, en forme de lame

Abrégé

Clostridium acetobutylicumcip-celcip-celClostridium acetobutylicumClostridium acetobutylicumClostridium acetobutylicum, as well as derivatives thereof with further modifications increasing growth on lignocellulosic biomass, and the use of these strains for the production of bulk chemicals by conversion of lignocellulose as source of carbon, such as ethanol, butanol, glycerol, 1,2-propanediol, acetone, isopropanol, isobutene, hydrogen, acetic acid and lactic acid and the like.

Classes IPC  ?

• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli

Abrégé

The invention relates to a treatment facility (1) for the treatment of fermentable solid products by fermentation, the facility comprising a reactor (2) supported by a frame and a cartridge (11) having an apertured region (110) for storing the product, the reactor (2) being provided with an inlet (3) for products to be treated, an outlet (4) for discharging the treated products, a biogas outlet (5), an opening (8) for inserting an inoculum and an opening (9) for discharging the leachate, the facility also comprising a tubular body (6) and a liquid/solid separator (7), the body (6) being closed at both ends by a closing element (100) movable between an open position and a closed position, wherein one of the ends (3) receives the products to be treated and the other of the ends (4) discharges the treated products, each cartridge (11) being slidably movable inside the body (6) and the liquid/solid separator (7) comprising a filter (12).

Classes IPC  ?

• C12M 1/107 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens pour recueillir les gaz de fermentation, p. ex. le méthane
• C12M 1/16 - Appareillage pour l'enzymologie ou la microbiologie contenant ou adaptés pour contenir des milieux solides
• C12M 1/26 - Inoculateur ou échantillonneur

Abrégé

The present invention concerns oxidative degradation of polysaccharides, and provides a composition, kit, and method for increasing the efficiency of recalcitrant cellulose degradation, using an auxiliary activity family 7 (AA7) enzymes and a polysaccharide monooxygenase enzyme (E.C. 1.14.99.-). Said AA7 enzyme comprises dehydrogenase activity (E.C. 1.1.1.-) and gluco-oligosaccharide oxidase activity (E.C. 1.1.3.-) and provides a novel “functionality” within a previously not described Glade of AA7 dehydrogenases.

Classes IPC  ?

• C12N 9/04 - Oxydoréductases (1.), p. ex. luciférase agissant sur des groupes CHOH comme donneurs, p. ex. oxydase de glucose, déshydrogénase lactique (1.1)
• C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase

Abrégé

The subject of the present invention is that of preparing glucosylated mycosporines by means of an enzymatic cascade method using α-transglucosylases and sucrose, and use thereof in particular for their anti-UV properties.

Classes IPC  ?

• C12P 19/44 - Préparation d'O-glucosides, p. ex. glucosides
• A61K 8/60 - SucresLeurs dérivés
• A61K 8/73 - Polysaccharides
• A61K 31/7032 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un polyol, c.-à-d. composés ayant plusieurs groupes hydroxyle, libres ou estérifiés, y compris le groupe hydroxyle impliqué dans la liaison glycosidique, p. ex. monoglucosyl-diacylglycérides, acide lactobionique, gangliosides
• A61K 31/716 - Glucanes
• A61P 17/16 - Émollients ou protecteurs, p. ex. contre les radiations
• A61P 27/12 - Agents ophtalmiques pour le traitement de la cataracte
• A61P 35/00 - Agents anticancéreux
• A61Q 17/04 - Préparations topiques pour faire écran au soleil ou aux radiationsPréparations topiques pour bronzer
• C12P 13/04 - Alpha- ou bêta-amino-acides
• C12P 13/00 - Préparation de composés organiques contenant de l'azote

Abrégé

The present disclosure relates to a hydrogel composition based on anionic cyclodextrin polymers and chitosan for use in the treatment of articular disorders. In particular, the hydrogel combines a pharmacological action, in particular an analgesic action, with a visco- supplementation (a lubricating effect).

Classes IPC  ?

• A61L 27/26 - Mélanges de matériaux macromoléculaires
• A61L 27/52 - Hydrogels ou hydrocolloïdes
• A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques

Abrégé

The present patent application relates to O-acetylserine, or a salt or derivative thereof, for use in the treatment and/or prevention of glucose intolerance and/or one or more diseases associated with glucose intolerance in an individual. The present patent application relates to O-acetylserine, or a salt or derivative thereof, for use in the treatment and/or prevention of glucose intolerance and/or one or more diseases associated with glucose intolerance in an individual. The invention also relates to a composition for use in the treatment and/or prevention of glucose intolerance and/or one or more diseases associated with glucose intolerance in an individual, comprising an O-acetylserine, or a salt or derivative thereof, and a physiologically acceptable vehicle.

Classes IPC  ?

• A61K 31/223 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p. ex. pravastatine d'alpha-amino-acides
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur

Abrégé

and introducing the used aqueous washing solution into a step of said biomass treatment process which is after the pretreatment step f), and/or into an enzyme production step and/or into a step of producing/propagating the microorganisms necessary for steps g) or h).

Classes IPC  ?

• C12P 7/06 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique
• C12P 7/04 - Préparation de composés organiques contenant de l'oxygène contenant un groupe hydroxyle acycliques
• C12P 7/16 - Butanols
• C12P 7/28 - Produits contenant de l'acétone

Abrégé

The present invention concerns a human T cell or NK cell comprising a nucleic acid construct which comprises a transgene which is placed under the control of a regulatory polynucleotide inducible by a deficiency in at least one essential amino acid, and cellular immunotherapy employing said human T cell or NK cell.

Classes IPC  ?

• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
• C12N 5/07 - Cellules animales ou tissus animaux

Abrégé

The present invention relates to an engineered unicellular Stramenopile microalga comprising a loss of function of the homologous Seipin gene, an in vitro method of producing triacylglycerols (TAG), and uses thereof.

Classes IPC  ?

• C07K 14/405 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'algues
• C12P 7/6463 - Glycérides obtenus à partir de micro-organismes, p. ex. huile d’organismes unicellulaires
• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• C12R 1/89 - Algues

Abrégé

The present invention provides protected tetrasaccharides, their process of preparation and their use in the synthesis of oligosaccharides, in particular fragments of O-antigens from Shigella flexneri, for example of serotype 1a, 1b, 2a, 2b, 3a, X, 4a, 4b, 5a, 5b, 7a or 7b.

Classes IPC  ?

• C07H 15/10 - Radicaux acycliques non substitués par des structures cycliques liés à un atome d'oxygène d'un radical saccharide contenant des liaisons non saturées carbone-carbone
• C12P 19/04 - Polysaccharides, c.-à-d. composés contenant plus de cinq radicaux saccharide reliés entre eux par des liaisons glucosidiques
• C12P 19/14 - Préparation de composés contenant des radicaux saccharide préparés par action d'une carbohydrase, p. ex. par action de l'alpha-amylase
• C12P 19/18 - Préparation de composés contenant des radicaux saccharide préparés par action d'une transférase glycosylique, p. ex. alpha-, bêta- ou gamma-cyclodextrines
• C12P 19/28 - N-glucosides
• C07H 15/203 - Carbocycles monocycliques autres que des cycles cyclohexaneSystèmes carbocycliques bicycliques
• C07H 13/04 - Composés contenant des radicaux saccharide estérifiés soit par l'acide carbonique ou ses dérivés, soit par des acides organiques, p. ex. acides phosphoniques par des acides carboxyliques comportant les radicaux carboxyle estérifiants liés à des atomes de carbone acycliques

Abrégé

The present invention relates to recombinant spriviviruses, in particular a recombinant spring viraemia of carp virus, uses thereof and methods for producing the same.

Classes IPC  ?

• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
• C12N 15/86 - Vecteurs viraux

Abrégé

The present invention relates to the field of protection against bacterial infectious diseases by means of compositions comprising bacteriophages. It concerns in particular an antibacterial composition comprising: at least one bacteriophage chosen from the Podoviridae, Myoviridae and Siphoviridae, as an active agent, in a liquid core, a gelled shell encapsulating the liquid core comprising said bacteriophage and comprising dispersed colloidal particles of UV screening agent, in which the UV screening agent is not a soluble antioxidant compound.

Classes IPC  ?

• A01N 63/40 - Virus, p. ex. bactériophages
• A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
• A61K 9/50 - Microcapsules
• A61K 35/76 - VirusParticules sous-viralesBactériophages
• A61K 47/06 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite