A surface-modified particle includes a core containing at least one oxidic material and at least one layer. The layer is obtained from at least one silicon compound and at least one silane according to formula(S). The silicon compound includes at least one building block of formula (A) and at least one building block of formula (B). A method is developed for preparing the surface-modified particle, and another method treats a surface of a substrate with at least one surface-modified particle. The surface-modified particle is added to various formulations, in particular a toner composition.
There is presented an in situ method of degradation of a fluoro-organic compound in an aqueous environment comprising at least soil and groundwater, the method comprising at least the steps of: (a) adding a sorptive media to the aqueous environment, the sorptive media being one or more of the group comprising: carbon, reactive organic and zero valent metal; (b) allowing the fluoro-organic compound to fix onto the sorptive media over a time period of greater than 24 hours; (c) providing an oxidant being reactive to the sorptive media; and (d) adding the oxidant to the aqueous environment to contact the sorptive media in situ at an oxidant concentration of ≥0.4M, and to initiate degradation of the fluoro-organic compound on the sorptive media when the temperature of the sorptive media is at least 65°C, so that one or more fluoro-degradation products are formed. The method relates to the in situ degradation of volatile and semi-volatile organic compounds, pesticides and other recalcitrant organic compounds in soil and groundwater, and includes soil remediation.
B09C 1/08 - Régénération de sols pollués par des procédés chimiques
C02F 1/58 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par élimination de composés spécifiés dissous
B09C 1/06 - Régénération de sols pollués par des procédés thermiques
B01J 20/00 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation
C02F 101/36 - Composés organiques contenant des atomes d'halogène
C02F 103/06 - Eau souterraine contaminée ou eau de lessivage
An aqueous antimicrobial composition is made with a low odor that has (a) a first volatile carboxylic acid, (b) a second non-volatile carboxylic acid, (c) a first percarboxylic acid, (d) a second percarboxylic acid, and (e) hydrogen peroxide. The molar ratio of the sum of the first carboxylic acid and the first percarboxylic acid to the sum of the second carboxylic acid and the second percarboxylic acid is from 1:5 to 5:1, preferably from 1:3 to 3:1. Processes are developed for producing the composition and sanitizing various surfaces with it.
A01N 59/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des éléments ou des composés inorganiques
A01N 25/02 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles contenant des liquides comme supports, diluants ou solvants
A01N 37/04 - Acides carboxyliques saturés ou leurs thio-analoguesLeurs dérivés polybasiques
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
An aged aqueous antimicrobial composition is prepared by mixing a carboxylic acid selected from maleic acid, crotonic acid, malic acid, tartaric acid, malonic acid, citric acid and mixtures thereof, with hydrogen peroxide; reacting the mixture to form a percarboxylic acid; and ageing the mixture that has the percarboxylic acid for at least 14 days.
A01N 37/36 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant au moins un groupe carboxylique ou un thio-analogue, ou d'un de leurs dérivés, et un atome d'oxygène ou de soufre lié par une liaison simple, liés au même squelette carboné, cet atome d'oxygène ou de soufre ne faisant pas partie d'un groupe carboxylique ou d'un thio-analogue, ou d'une de leurs dérivés, p. ex. acides hydroxycarboxyliques
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
A process for sterilization or disinfection treatment includes: a) obtaining a hydrogen peroxide vapour from an aqueous hydrogen peroxide solution having a dry residue determined at 105° C. of at most 5 ppm and a total content of Fe, Cr, Mn and Ni in the solution of at most 6 ppb as determined by ICP-MS analysis; and b) treating an object to be sterilized or disinfected with the hydrogen peroxide vapour obtained in a).
A61L 2/20 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances gazeuses, p. ex. des vapeurs
A23B 7/144 - Conservation ou mûrissement à l'aide de produits chimiques non couverts par les groupes ou sous forme de gaz, p. ex. fumigationCompositions ou appareils à cet effet
A61L 2/22 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances à phases, p. ex. des fumées, des aérosols
C01B 15/023 - Préparation à partir de composés organiques par le procédé utilisant une alkylanthraquinone
The present invention relates in general to compositions and methods for treating an animal or human patient in need of treatment for ophthalmic diseases or conditions involving oxidative stress and treatment with an ophthalmic implant containing (2R,2R')-3,3'-disulfanediyl bis(2-acetamidopropanamide) (diNACA), wherein such ophthalmic diseases or conditions include but not limited to cataracts, cataracts in a subject that does not have diabetes, corneal endothelial cell loss, age-related macular degeneration, presbyopia, retinitis pigmentosa (RP), Usher syndrome, Stargardt syndrome, glaucoma, diabetic retinopathy, and/or retinal disease.
The present invention discloses a method for increasing a conversion rate of a (trans)esterification reaction for preparing a (meth)acrylate product.of a reaction mixture in a reactor system, the reactor system comprising a reboiler, a reaction chamber comprising the reaction mixture, a column with a column head, a vapor transfer line, a condenser, a reflux tank, a reflux line, a distillate take off line, and a receiver vessel, wherein the reaction mixture comprises at least one starting material which is converted by the reaction into at least one product, wherein the reaction mixture comprises (meth)acrylic acid as first starting material and a first alcohol as second starting material which are converted by the esterification reaction into a (meth)acrylate as a first product and water as a second product, or wherein in case of a transesterification reaction the reaction mixture comprises a (meth)acrylate as first starting material and a first alcohol as second starting material which are converted by the transesterification reaction into a second (meth)acrylate as a first product and a second alcohol as a second product, wherein while the reaction is running at least a portion of at least one of the products is removed by distillate take off, wherein the conversion rate of the reaction is increased by an intermediate increased or full removal of the at least one of the products present in the column, the column head and the condenser, and wherein - the intermediate increased or full removal of the at least one of the products present in the column, the column head, and the condenser while the reaction is running is performed by maximizing distillate take off and/or - during the intermediate increased or full removal of the at least one of the products present in the column, the column head and the condenser, the filling level for the reflux tank is minimized and the concentration of the removed products in the distillate is below a concentration of 50 wt%.
The organophilic clay comprises a smectite-type clay ion exchanged with quaternary ammonium ions, where at least 75 mol-% of said quaternary ammonium ions are bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters and at least 90% of the fatty acid moieties of the bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters have a structure RC(O) with group R being a linear alkyl or alkenyl group containing from 9 to 21 carbon atoms. The organophilic clay is useful for thickening oil based compositions, in particular drilling fluids for drilling oil or gas wells, comprising an oil phase.
The present invention relates to a surface-modified particle for use in a toner composition, a method of preparing the surface-modified particle according to the invention, a method for treating a surface of a substrate with at least one particle according to the invention, a substrate having a treated surface with at least one particle according to the invention, use of the at least one surface- modified particle according to the invention as additive in various formulations and in particular a toner composition comprising the surface-modified particle according to the invention.
The present invention relates to an aged aqueous antimicrobial composition prepared by (a) mixing a carboxylic acid selected from maleic acid, crotonic acid, malic acid, tartaric acid, malonic acid, citric acid or mixtures thereof, with hydrogen peroxide; (b) reacting the mixture obtained in step a) to form a percarboxylic acid; and c) ageing the mixture comprising the percarboxylic acid for at least 14 days.
A01N 25/02 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles contenant des liquides comme supports, diluants ou solvants
A01N 37/02 - Acides carboxyliques saturés ou leurs thio-analoguesLeurs dérivés
A01N 37/06 - Acides carboxyliques non saturés ou leurs thio-analoguesLeurs dérivés
A01N 37/36 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant au moins un groupe carboxylique ou un thio-analogue, ou d'un de leurs dérivés, et un atome d'oxygène ou de soufre lié par une liaison simple, liés au même squelette carboné, cet atome d'oxygène ou de soufre ne faisant pas partie d'un groupe carboxylique ou d'un thio-analogue, ou d'une de leurs dérivés, p. ex. acides hydroxycarboxyliques
The present invention relates to an aqueous antimicrobial composition with a low odor, comprising (a) a first volatile carboxylic acid, (b) a second non-volatile carboxylic acid, (c) a first percarboxylic acid, (d) a second percarboxylic acid, and (e) hydrogen peroxide, wherein the molar ratio of the sum of the first carboxylic acid and the first percarboxylic acid to the sum of the second carboxylic acid and the second percarboxylic acid is from 1:5 to 5:1, preferably from 1:3 to 3:1, a process for producing thereof and the use thereof for antimicrobial treatment.
A01N 37/02 - Acides carboxyliques saturés ou leurs thio-analoguesLeurs dérivés
A01N 37/06 - Acides carboxyliques non saturés ou leurs thio-analoguesLeurs dérivés
A01N 59/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des éléments ou des composés inorganiques
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
A23B 4/12 - Conservation au moyen d'acidesFermentation acide
A23B 7/10 - Conservation au moyen d'acidesFermentation acide
A01N 37/36 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant au moins un groupe carboxylique ou un thio-analogue, ou d'un de leurs dérivés, et un atome d'oxygène ou de soufre lié par une liaison simple, liés au même squelette carboné, cet atome d'oxygène ou de soufre ne faisant pas partie d'un groupe carboxylique ou d'un thio-analogue, ou d'une de leurs dérivés, p. ex. acides hydroxycarboxyliques
A process for sterilization or disinfection treatment, comprising the following steps: a) obtaining a hydrogen peroxide vapour from an aqueous hydrogen peroxide solution having a dry residue determined at 105 °C of at most 5 ppm and a total content of Fe, Cr, Mn and Ni in the solution of at most 6 ppb as determined by ICP-MS analysis; b) treatment of an object to be sterilized or disinfected with a hydrogen peroxide vapour obtained in step a).
A61L 2/20 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances gazeuses, p. ex. des vapeurs
A61L 2/22 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances à phases, p. ex. des fumées, des aérosols
A23B 7/144 - Conservation ou mûrissement à l'aide de produits chimiques non couverts par les groupes ou sous forme de gaz, p. ex. fumigationCompositions ou appareils à cet effet
C01B 15/00 - PeroxydesPeroxyhydratesPeroxyacides ou leurs selsSuperoxydesOzonides
14.
COMPOSITION FOR MANUFACTURING SHEET MOLDING COMPOUNDS
The present invention relates to a composition suitable for manufacturing of sheet molding compounds, a method for preparing said composition, a method for making an article using said composition, an article with said composition, a mobility device comprising at least one such article. It is further directed at the use of at least one silane, a hydrolysate, an oligomer or a polymer thereof, to control the viscosity of a liquid mixture comprising an unsaturated polyester and at least one hollow glass body.
C03C 17/00 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement
C03C 17/30 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement par des matières organiques avec des composés contenant du silicium
C08J 3/205 - Formation de mélanges de polymères avec des additifs, p. ex. coloration en présence d'une phase liquide
C09D 183/00 - Compositions de revêtement à base de composés macromoléculaires obtenus par des réactions créant dans la chaîne principale de la macromolécule une liaison contenant uniquement du silicium, avec ou sans soufre, azote, oxygène ou carboneCompositions de revêtement à base de dérivés de tels polymères
C08K 9/06 - Ingrédients traités par des substances organiques par des composés contenant du silicium
C08K 9/08 - Ingrédients agglomérés par traitement avec un liant
The present invention generally relates to methods for curing and/or manufacturing silicone-coated release liners used e.g., in the production of pressure sensitive, peel-and-stick labels. In particular, the present invention is directed to silicone release coatings curable by LED, and methods for preparing silicone release coatings and curing such coatings with or without the need for nitrogen inerting or the addition of oxygen scavengers.
C09D 183/06 - Polysiloxanes contenant du silicium lié à des groupes contenant de l'oxygène
C09J 4/06 - Adhésifs à base de composés non macromoléculaires organiques ayant au moins une liaison non saturée carbone-carbone polymérisable en combinaison avec un composé macromoléculaire autre qu'un polymère non saturé des groupes
C09J 183/06 - Polysiloxanes contenant du silicium lié à des groupes contenant de l'oxygène
C08J 5/12 - Fixation d'un matériau macromoléculaire préformé au même matériau ou à un autre matériau compact, tel que du métal, du verre, du cuir, p. ex. en utilisant des adhésifs
C09J 1/00 - Adhésifs à base de constituants inorganiques
C09J 5/00 - Procédés de collage en généralProcédés de collage non prévus ailleurs, p. ex. relatifs aux amorces
17.
ANTI-CORROSION KIT AND ANTI-CORROSION AGENT FORMED THEREFROM
The present invention concerns an anti-corrosion agent, a kit-of-parts for preparing said anti-corrosion agent, a method for preparing said anti-corrosion agent and an anti-corrosion layer as well as a method for providing said layer.
C09D 183/14 - Compositions de revêtement à base de composés macromoléculaires obtenus par des réactions créant dans la chaîne principale de la macromolécule une liaison contenant uniquement du silicium, avec ou sans soufre, azote, oxygène ou carboneCompositions de revêtement à base de dérivés de tels polymères dans lesquels au moins deux atomes de silicium, mais pas la totalité, sont liés autrement que par des atomes d'oxygène
Aqueous solutions of peroxyacids are stabilized by a polymeric stabilizer selected from a phosphino polycarboxylic acid, a poly(acrylic acid)-acrylamidoalkylpropane sulfonic acid co-polymer, or a poly(acrylic acid)-acrylamidoalkylpropane sulfonic acid-sulfonated styrene terpolymer. The polymer-stabilized peroxyacid solutions have applications in aseptic sterilization and disinfecting of surfaces.
A01N 25/02 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles contenant des liquides comme supports, diluants ou solvants
A01N 25/22 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles contenant des ingrédients stabilisant les ingrédients actifs
A01N 37/16 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant le groupe Leurs thio-analogues
19.
Organophilic clays and drilling fluids containing them
The organophilic clay comprises a smectite-type clay ion exchanged with quaternary ammonium ions, where at least 75 mol-% of said quaternary ammonium ions are bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters and at least 90% of the fatty acid moieties of the bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters have a structure RC(O) with group R being a linear alkyl or alkenyl group containing from 9 to 21 carbon atoms. The organophilic clay is useful for thickening oil based compositions, in particular drilling fluids for drilling oil or gas wells, comprising an oil phase.
Cannabinoid may be separated from plant extract by mixing polar solvent and plant extract and subjecting the resulting mixture to a first nanofiltration operation including a silicone acrylate membrane layer on a polyimide support. Permeate from the first nanofiltration operation may be subjected to a second nanofiltration operation to provide a retentate enriched in cannabinoid compound and a second permeate including the solvent. The second nanofiltration operation may include the use of a membrane having a molecular weight cut off of between 150 g/mol and 350 g/mol.
The invention relates to functionalized polymers, a process for producing functionalized polymers and the use of functionalized polymers, especially in the field of personal care.
A61K 38/00 - Préparations médicinales contenant des peptides
A61Q 5/00 - Préparations pour les soins des cheveux
C08F 220/18 - Esters des alcools ou des phénols monohydriques des phénols ou des alcools contenant plusieurs atomes de carbone avec l'acide acrylique ou l'acide méthacrylique
A61K 8/81 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons insaturées carbone-carbone
A61Q 1/02 - Préparations contenant des colorants cutanés, p. ex. pigments
Described herein are packages for orienting and cooling polyesters during a sterilization process, and containers for storing, transporting, and cooling the package. Also described herein are methods of sterilizing polyesters.
A61L 2/08 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des phénomènes physiques des radiations
B65D 81/18 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu fournissant une ambiance spécifique pour le contenu, p. ex. température supérieure ou inférieure à la température ambiante
23.
A DEVICE AND A MEMBRANE PROCESS FOR SEPARATING GAS COMPONENTS FROM A GAS STREAM HAVING VARYING COMPOSITION OR FLOW RATE
A device for separating a gas stream which has a compressor and three membrane separation units in series, connected to pass the retentate stream of each of the first two units to the subsequent membrane separation unit, comprises conduits for recycling the permeate streams of the second and the third membrane separation unit to upstream of the compressor and a control device controlling the fraction of the second permeate stream which is recycled. Adjusting which fraction of the second permeate is recycled can be used to maintain a target composition of the retentate obtained in the third membrane separation unit when the flow rate or the composition of the gas stream changes.
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
C10L 3/10 - Post-traitement de gaz naturel ou de gaz naturel de synthèse
B01D 53/30 - Commande par appareil d'analyse des gaz
24.
PROCESS FOR PREPARING A STABILIZED AQUEOUS HYDROGEN PEROXIDE SOLUTION
In a process for preparing hydrogen peroxide by an anthraquinone process, comprising hydrogenating a working solution comprising an anthraquinone compound, oxidizing the hydrogenated working solution to form hydrogen peroxide and extracting the hydrogen peroxide with water, the extracted aqueous hydrogen peroxide solution is stabilized with one or more oxidizer stable polymeric stabilizers.
Aqueous solutions of peroxyacids are stabilized by a polymeric stabilizer selected from a phosphino polycarboxylic acid, a poly(acrylic acid)-acrylamidoalkylpropane sulfonic acid copolymer, or a poly(acrylic acid)-acrylamidoalkylpropane sulfonic acid-sulfonated styrene terpolymer. The polymer-stabilized peroxyacid solutions have applications in aseptic sterilization and disinfecting of surfaces.
A01N 37/16 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant le groupe Leurs thio-analogues
A01N 25/22 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles contenant des ingrédients stabilisant les ingrédients actifs
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
Aqueous solutions of hydrogen peroxide and alkali metal chlorate are stabilized by a polymeric stabilizer selected from phosphino polycarboxylic acid, poly(acrylic acid), a poly(acrylic acid)- acrylamidoalkylpropane sulfonic acid co-polymer and a poly(acrylic acid)-acrylamidoalkylpropane sulfonic acid-sulfonated styrene terpolymer.
Aqueous solutions of hydrogen peroxide are stabilized by at least one polymeric stabilizer selected from phosphino polycarboxylic acids, poly(acrylic acid)-acrylamidoalkylpropane sulfonic acid co-polymers and poly(acrylic acid)-acrylamidoalkylpropane sulfonic acid-sulfonated styrene terpolymers. The polymer-stabilized hydrogen peroxide solutions have applications in aseptic packaging, electronics manufacture, and pulp and paper bleaching.
A modified colloidal silica is produced by mixing an effective amount of an alkyl silicate to form a colloidal silica, followed by treating the colloidal silica with an effective amount of a polyethersilane to form a modified colloidal silica.
A wearable device (204) comprising: a base coupled to a user; a recessed portion formed in the base; a microneedle array (200) supported by the base wherein the microneedle array includes a plurality of microneedles; and an actuator (208) coupled to the microneedle array to move the microneedle array into and out of the recessed portion in the base.
A61B 5/15 - Dispositifs de prélèvement d'échantillons de sang
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61M 37/00 - Autres appareils pour introduire des agents dans le corpsPercutanisation, c.-à-d. introduction de médicaments dans le corps par diffusion à travers la peau
Described herein are microneedle arrays for delivery of medicinal formulations. The microneedle arrays includes an anchoring system for securing the microneedle arrays to the skin for a period of time, e.g., a treatment period. The microneedles in the array also may include a coating, such as a lubricious coating for ease of puncturing/penetrating the skin or anti-microbial agents.
A61M 37/00 - Autres appareils pour introduire des agents dans le corpsPercutanisation, c.-à-d. introduction de médicaments dans le corps par diffusion à travers la peau
The invention relates to functionalized polymers, a process for producing functionalized polymers and the use of functionalized polymers, especially in the field of personal care.
C08F 220/18 - Esters des alcools ou des phénols monohydriques des phénols ou des alcools contenant plusieurs atomes de carbone avec l'acide acrylique ou l'acide méthacrylique
A61Q 5/00 - Préparations pour les soins des cheveux
32.
METHOD AND DEVICE FOR A POLYESTER STERILIZATION PROCESS
Described herein are packages for orienting and cooling polyesters during a sterilization process, and containers for storing, transporting, and cooling the package. Also described herein are methods of sterilizing polyesters.
A61L 2/08 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des phénomènes physiques des radiations
B65D 55/02 - Dispositifs de blocageMoyens pour empêcher ou indiquer l'ouverture ou l'enlèvement de la fermeture non autorisés
33.
METHOD AND DEVICE FOR A POLYESTER STERILIZATION PROCESS
Described herein are packages for orienting and cooling polyesters during a sterilization process, and containers for storing, transporting, and cooling the package. Also described herein are methods of sterilizing polyesters.
The present invention is directed to an improved purification process using additive and activated carbon for purifying resorbable polymers suitable for industrial manufacturing. The metal catalyst concentration in the purified resorbable polymers of this invention is preferably less than 1 ppm. The method can be used to obtain high molecular weight polymers that are substantially metal free.
Salt-tolerant friction-reducing terpolymer compositions are provided. The compositions can be used in a method of reducing friction resulting from turbulent flow in an aqueous fracturing fluid in a subterranean fracturing process.
The organophilic clay comprises a smectite-type clay ion exchanged with quaternary ammonium ions, where at least 75 mol-% of said quaternary ammonium ions are bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters and at least 90% of the fatty acid moieties of the bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters have a structure RC(O) with group R being a linear alkyl or alkenyl group containing from 9 to 21 carbon atoms. The organophilic clay is useful for thickening oil based compositions, in particular drilling fluids for drilling oil or gas wells, comprising an oil phase.
The organophilic clay comprises a smectite-type clay ion exchanged with quaternary ammonium ions, where at least 75 mol-% of said quaternary ammonium ions are bis-(2-hydroxypropyl)- dimethylammonium fatty acid esters and at least 90 % of the fatty acid moieties of the bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters have a structure RC(O) with group R being a linear alkyl or alkenyl group containing from 9 to 21 carbon atoms. The organophilic clay is useful for thickening oil based compositions, in particular drilling fluids for drilling oil or gas wells, comprising an oil phase.
C01B 33/36 - Silicates ayant des propriétés d'échangeurs de base, mais n'ayant pas de propriétés de tamis moléculaires
C01B 33/38 - Silicates échangeurs de base en couches, p. ex. argiles, micas ou silicates de métaux alcalins du type kenyaïte ou magadiite
C01B 33/44 - Produits obtenus à partir de silicates échangeurs de base, en couches, par échange d'ions avec des composés organiques tels que des composés ammonium, phosphonium ou sulfonium ou par insertion de composés organiques, p. ex. matériaux organoargiles
The use of a single phase aqueous hydrogen peroxide composition, comprising from 5 to 75 % by weight of hydrogen peroxide and from 3 to 150 mg/kg of at least one alkyl phosphate, the composition having a total organic carbon content from organic compounds other than alkyl phosphates of less than 200 mg/kg, reduces foam formation in a method for producing chlorine dioxide by reacting an alkali chlorate with hydrogen peroxide composition in an acidic aqueous medium boiling at sub-atmospheric pressure.
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61Q 11/00 - Préparations pour le nettoyage des dents, de la bouche ou des prothèses dentaires, p. ex. dentifricesBains de bouche
C09D 4/00 - Compositions de revêtement, p. ex. peintures, vernis ou vernis-laques, à base de composés non macromoléculaires organiques ayant au moins une liaison non saturée carbone-carbone polymérisable
C09D 5/00 - Compositions de revêtement, p. ex. peintures, vernis ou vernis-laques, caractérisées par leur nature physique ou par les effets produitsApprêts en pâte
E01C 23/00 - Dispositifs ou dispositions auxiliaires pour la construction, la réparation, la remise en état ou la dépose de routes ou de surfaces similaires
The disclosure is directed in part to extended release compositions that include hydroxy progesterone caproate. For example, provided herein is a therapeutic microparticle composition comprising a plurality of microparticles, wherein the microparticles each comprise poly (lactide-co-glycolide) and hydroxyprogesterone caproate.
A61K 31/57 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne à deux atomes de carbone, p. ex. prégnane ou progestérone
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
chemical reagents, other than for medical or veterinary purposes, namely, formulated reagents for the remediation of contaminants in soil and groundwater environments
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
Lecithin-based substrate of food-grade organic carbon used to enhance anaerobic bioremediation; organic carbon substrate used for bioremediation of contaminated soil and groundwater; chemicals used in industry, science and photography, as well as in agriculture, horticulture and forestry.
45.
FRICTION REDUCING TERPOLYMER COMPOSITIONS AND METHOD OF FRACTURING
Salt-tolerant friction-reducing terpolymer compositions are provided. The compositions can be used in a method of reducing friction resulting from turbulent flow in an aqueous fracturing fluid in a subterranean fracturing process.
C08F 216/02 - Copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et l'un au moins étant terminé par un radical alcool, éther, aldéhyde, cétone, acétal ou cétal par un radical alcool
Salt-tolerant friction-reducing terpolymer compositions are provided. The compositions can be used in a method of reducing friction resulting from turbulent flow in an aqueous fracturing fluid in a subterranean fracturing process.
The present invention is directed to a method for the treatment of an environmental medium contaminated with arsenic, comprising treating such medium with an effective amount of persulfate and zero valent iron.
The present invention is directed to a method for the treatment of an environmental medium contaminated with arsenic, comprising treating such medium with an effective amount of persulfate and zero valent iron.
The present invention relates to a fast particulate superabsorbent polymer composition comprising a polymer comprising a neutralized aluminum salt solution applied to the surface of a particulate superabsorbent polymer; wherein an aqueous solution of the neutralized aluminum salt has a pH value from about 5.5 to about 8; and subsequent to subjecting the particulate superabsorbent polymer composition to the Processing Test, the particulate superabsorbent polymer composition has a permeability stability index of from about 0.60 to about 0.99, and a compressibility from 1.30mm2/N to about 4mm2/N as measured by the Compression Test, and wherein the particulate superabsorbent polymer composition may have a Vortex time of from 25 to 60 seconds and absorbency under load at 0.9psi of from 15 to 21g/g.
A61L 15/00 - Aspect chimique des bandages, des pansements ou des garnitures absorbantes ou utilisation de matériaux pour leur réalisation
C08J 3/24 - Réticulation, p. ex. vulcanisation, de macromolécules
C08F 220/06 - Acide acryliqueAcide méthacryliqueLeurs sels métalliques ou leurs sels d'ammonium
B01J 20/00 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation
51.
PARTICULATE SUPERABSORBENT POLYMER COMPOSITION HAVING IMPROVED STABILITY
The present invention relates to a particulate superabsorbent polymer composition comprising a polymer comprising a neutralized aluminum salt solution applied to the surface of a particulate superabsorbent polymer; wherein an aqueous solution of the neutralized aluminum salt has a pH value from about 5.5 to about 8 and the particulate superabsorbent polymer composition has a mean particle size distribution of from 300 to 400μm, an original Free Swell Gel Bed Permeability (FSGBP) of about 20x10-8 cm2 to about 200x10-8 cm2; and subsequent to subjecting the particulate superabsorbent polymer composition to the Processing Test, the particulate superabsorbent polymer composition has a permeability stability index of from about 0.60 to about 0.99 and having particles having a particle diameter of larger than 600μm in an amount of less than about 15wt% of the particulate superabsorbent polymer composition and as specified by standard sieve classification.
A61L 15/00 - Aspect chimique des bandages, des pansements ou des garnitures absorbantes ou utilisation de matériaux pour leur réalisation
C08J 3/24 - Réticulation, p. ex. vulcanisation, de macromolécules
C08F 220/06 - Acide acryliqueAcide méthacryliqueLeurs sels métalliques ou leurs sels d'ammonium
B01J 20/00 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation
52.
PARTICULATE SUPERABSORBENT POLYMER COMPOSITION HAVING IMPROVED STABILITY
The present invention relates to a particulate superabsorbent polymer composition comprising a polymer comprising a neutralized aluminum salt solution applied to the surface of a particulate superabsorbent polymer; wherein an aqueous solution of the neutralized aluminum salt has a pH value from about 5.5 to about 8 and the particulate superabsorbent polymer composition has a mean particle size distribution of from 300 to 400μm, an original Free Swell Gel Bed Permeability (FSGBP) of about 20x10-8 cm2 to about 200x10-8 cm2; and subsequent to subjecting the particulate superabsorbent polymer composition to the Processing Test, the particulate superabsorbent polymer composition has a permeability stability index of from about 0.60 to about 0.99 and having particles having a particle diameter of larger than 600μm in an amount of less than about 15wt% of the particulate superabsorbent polymer composition and as specified by standard sieve classification.
Detergent compositions and detergent compositions dispersed in personal care products are provided herein. In one embodiment, a detergent composition is provided and comprises a sorbent carrier. The detergent composition also includes a sorbed component including an acid and a surfactant. The sorbed component is sorbed by the sorbent carrier.
Described herein are drying methods for tuning one or more properties of a microparticle. In one aspect, the release profile of a microparticle comprising a bioactive agent therein can be affected by the disclosed drying methods.
The described invention provides a biodegradable, biocompatible delivery system of flowable sustained release microparticulate composition of a substantially pure crystalline form of a bioactive agent such as, for example, nimodipine, a process of preparing a therapeutic form of a substantially pure crystalline form of the bioactive agent and a method for treating an interruption of a cerebral artery in a subarachnoid space at risk of interruption caused by brain injury in a mammal, which reduces signs or symptoms of at least one delayed complication associated with brain injury.
The present invention is directed to a method of oxidizing an organic compound present in soil, groundwater, process water or wastewater comprising contacting such organic compound with a persulfate and an organic acid selected from the group consisting of ascorbic acid, formic acid, oxalic acid, lactic acid and citric acid, wherein the molar ratio of such organic acid to persulfate is between 1:100 and 3:1.
A62D 3/00 - Procédés pour rendre les substances chimiques nuisibles inoffensives ou moins nuisibles en effectuant un changement chimique dans les substances
B09C 1/08 - Régénération de sols pollués par des procédés chimiques
C02F 1/54 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par floculation ou précipitation d'impuretés en suspension utilisant des produits organiques
C02F 1/72 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par oxydation
C07C 27/16 - Procédés impliquant la production simultanée de plusieurs classes de composés contenant de l'oxygène par oxydation d'hydrocarbures avec d'autres produits oxydants
The present invention is directed to a method of oxidizing an organic compound present in soil, groundwater, process water or wastewater comprising contacting such organic compound with a persulfate and an organic acid selected from the group consisting of ascorbic acid, formic acid, oxalic acid, lactic acid and citric acid, wherein the molar ratio of such organic acid to persulfate is between 1:100 and 3:1.
The invention relates to a superabsorbent copolymer comprising a reaction product of a reactive optical brightener comonomer. In another embodiment, the superabsorbent copolymer comprises a reaction product of a first monomer and a reactive optical brightener comonomer. The reactive optical brightener comonomer may be selected from various pyrene optical brighteners listed herein. The invention also relates to superabsorbent copolymer having from about 0.1 to 10,000 ppm of a reactive optical brightener comonomer based on the superabsorbent copolymer.
The present invention further relates to a particulate superabsorbent polymer composition comprising a crosslinker composition that is the reaction product selected from (i) saturated amines and/or saturated polyamines with ethylenically unsaturated glycidyl compounds and/or ethylenically unsaturated polyglycidyl compounds, (ii) ethylenically unsaturated amines and/or ethylenically unsaturated polyamines with saturated glycidyl compounds and/or saturated polyglycidyl compounds, or (iii) ethylenically unsaturated amines and/or ethylenically unsaturated polyamines with ethylenically unsaturated glycidyl compounds and/or ethylenically unsaturated polyglycidyl compounds; and a surface crosslinking agent applied to the particle surface. The present invention further relates to an absorbent article that includes such particulate superabsorbent polymer compositions.
The present invention further relates to a process to make a superabsorbent polymer comprising the steps of a) preparing a neutralized monomer solution comprising a polymerizable monomer selected from unsaturated acid groups-containing monomers, ethylenically unsaturated carboxylic acid anhydride, salts, or derivatives thereof and a caustic agent selection from an alkali agent, wherein the polymerizable monomer is neutralized to from about 50mol% to about 85mol%; b) forming a crosslinker monomer mixture by adding an internal crosslinker composition to the neutralized monomer solution wherein the internal crosslinking composition is the reaction product of a stoichiometric excess of amine with a glycidyl compound, wherein the internal crosslinker composition has a residual amount of glycidyl compounds of less than about 500ppm based on the mass of the internal crosslinker composition; and c) polymerizing the crosslinker monomer mixture to make a superabsorbent polymer.
The present invention relates to a particulate superabsorbent polymer composition which absorbs water, aqueous liquids, and blood, and a process to make the superabsorbent polymers, wherein a superabsorbent polymer is surface treated with a neutralized multivalent metal salt solution having a pH value similar as that of human skin. The present invention also relates to particulate superabsorbent polymer composition having high Gel Bed Permeability and high Absorbency Under Load.
Disclosed herein are an apparatus and a method for producing emulsions, and, in particular, for maintaining laminar flow during production of emulsions containing microsuspensions. The apparatus relates to a column (10) for receiving a packing material, wherein at least one divider (50) is positioned within the interior cavity of the column, each divider of the at least one divider extending at least a position of the longitudinal length of the interior cavity and being configure to partition the packing material.
Disclosed herein are branched polyol polyesters, which are useful in pharmaceutical formulations. Also disclosed are blends, microparticles, and other formulations, comprising the branched polyol polyesters.
Disclosed herein are methods comprising suspending microparticles in a surfactant/non-polar alkane solution to remove residual solvent that is present in the microparticle.
The method disclosed herein comprises using a non-polar alkane in the continuous phase of an emulsion process to aid in the removal of dispersed phase solvent from the microparticles. The microparticles can further be subjected to a post-production treatment process, involving a non-polar alkane suspension and a rinse, to further reduce residual dispersed phase solvent levels.
A drug delivery blade for delivering a drug depot to a treatment site in a patient is disclosed. The drug delivery blade includes a shaft defining a longitudinal axis of the blade, a lumen that extends longitudinally from a proximal end of the shaft to a distal end of the shaft, a first beveled cut that forms a sharpened tip at the distal end of the shaft, and a flared portion near the distal end of the shaft. The flared portion of the blade includes two radially- extending blade segments having sharpened leading edges that allow the drug delivery blade to cut tissue when the blade is advanced toward a treatment site. Methods of using the drug delivery blade are also disclosed.
A61M 35/00 - Dispositifs pour appliquer des agents, p. ex. des remèdes, sur le corps humain
A61M 37/00 - Autres appareils pour introduire des agents dans le corpsPercutanisation, c.-à-d. introduction de médicaments dans le corps par diffusion à travers la peau
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
Disclosed herein are terpolymers and blends prepared from polyester terpolymers that can function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymer and terpolymer blends coated to a conformable backing member. The terpolymer and terpolymer blends can further comprise a bioactive agent.
C09J 7/00 - Adhésifs sous forme de films ou de pellicules
C09J 167/00 - Adhésifs à base de polyesters obtenus par des réactions créant une liaison ester carboxylique dans la chaîne principaleAdhésifs à base de dérivés de tels polymères
A61L 15/62 - Matériaux hydrosolubles ou hydrodégradables
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 31/06 - Matériaux macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 24/04 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie contenant des matériaux macromoléculaires
Disclosed herein are terpolymers that can function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymers adhered to a release liner. The disclosed implant devices comprise the pressure-sensitive adhesive terpolymer adhered to a surface thereof. The pressure-sensitive adhesive terpolymer can promote adhesion of the implant device to a location in a subject.
A61L 15/62 - Matériaux hydrosolubles ou hydrodégradables
A61L 24/04 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie contenant des matériaux macromoléculaires
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 31/06 - Matériaux macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
Disclosed herein are blends prepared from polyester terpolymers that function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymer blends adhered to a release liner. The disclosed implant devices comprise the pressure-sensitive adhesive blend adhered to a surface thereof. The pressure-sensitive adhesive blend can promote adhesion of the implant device to a location in a subject.
A61L 15/26 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carboneLeurs dérivés
A61L 24/04 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie contenant des matériaux macromoléculaires
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 31/06 - Matériaux macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
C08L 67/04 - Polyesters dérivés des acides hydroxycarboxyliques, p. ex. lactones
C09J 7/00 - Adhésifs sous forme de films ou de pellicules
The disclosed process comprises freeze-drying a biodegradable implant device comprised or one or more polyesters to thereby reduce moisture content in the device.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 31/06 - Matériaux macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
C08L 67/04 - Polyesters dérivés des acides hydroxycarboxyliques, p. ex. lactones
C09J 7/00 - Adhésifs sous forme de films ou de pellicules
The core-sheath implant device allows for a bioactive agent release profile that can be tailored to a particular therapy. The device features one or more lobes extending from an inner core at least partially through the outer sheath. Depending on the particular design of such an implant device, a variety of release profiles can be achieved.
Disclosed herein are processes for preparing implants that are particularly useful for thermally labile bioactive agents but can also generally be used with any bioactive agent. The disclosed processes avoid the use of heat during processing and therefore avoid heat induced degradation of the bioactive agent. Also disclosed are implants prepared by the disclosed methods.
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
78.
COMPOSITIONS AND METHODS FOR IMPROVED RETENTION OF A PHARMACEUTICAL COMPOSITION AT A LOCAL ADMINISTRATION SITE
Disclosed herein are compositions comprising cross-linkers for cross-linking a retention vehicle polymer. The compositions are particularly useful for local administration of a bioactive agent, wherein prolonged or extended availability of the bioactive agent at the site of administration is desired. Also disclosed are methods of delivering the compositions to a subject.
Disclosed herein are systems and methods useful for delivery of suspensions and other microparticle compositions, and, in particular, for delivering microparticles at desired dosing levels and eliminating blockages within microparticle suspensions positioned within a delivery device.
Disclosed herein are surface-active biodegradable block copolymers comprising one or more hydrophobic blocks and one or more hydrophilic blocks. The surface-active polymers are used as stabilizers in emulsions which are used in microencapsulation processes. Also disclosed are microparticles prepared from the emulsions.
The present invention relates to emulsion and double-emulsion based processes for preparing microparticles. The invention also relates to workhead assemblies for in-line flow-through mixing devices that can be used for mixing two or more fluids. The workhead assemblies can be used with the processes for preparing microparticles.
Disclosed herein are processes for preparing cyclic esters comprising unsaturated functional groups. Also disclosed are copolymers prepared from the cyclic esters. The copolymers can be used to form microparticles, polymer micelles, etc., which are useful in drug delivery applications.
Disclosed herein are pharmaceutical compositions comprising microparticles of ranibizumab that are useful for treating or preventing age-related macular degeneration. Also disclosed herein are microparticles that can be used to treat or prevent macular angiogenesis. Further disclosed are methods of making the microparticles and compositions and methods for treating or preventing macular degeneration and diseases, illnesses, or conditions relating to increased or abnormal macular angiogenesis.
Described herein are implant devices comprising at least one exposed biodegradable inner core surface, the inner core being surrounding partially by a membrane sheath which comprises a biocompatible polymer. A bioactive agent can be released from the inner core.
Described herein are implant devices comprising various configurations of bioactive agent loading which can be selected and used to tailor a particular bioactive agent release profile from the implant device.
Described herein are implant devices, kits comprising the implant devices, and methods of making and using the devices and kits. In one aspect, a plurality implant devices comprises at least two implants that exhibit a different release profile of a bioactive agent. In another aspect, an implant device comprises one or more adjoined polymer bodies, wherein at least two of the polymer bodies provide a different release profile of a bioactive agent. In another aspect, a kit comprises one or more disclosed implant devices. In another aspect, methods of delivering a bioactive agent to a subject comprise administering to the subject one or more disclosed implant devices.
Disclosed herein are compositions that exhibit viscosities suitable for injectable formulations. The compositions comprise bioactive agent-loaded microparticles and hyaluronic acid or a salt thereof in a suitable liquid pharmaceutical carrier. Also disclosed are methods of making and using the compositions.
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
88.
CONTINUOUS DOUBLE EMULSION PROCESS FOR MAKING MICROPARTICLES
Described herein are improved methods for microparticle encapsulation. In one aspect, the disclosed methods comprise a substantially continous double emulsion process. In a further aspects, microparticles comprising a bioactive agent therein are made by the disclosed methods.
Described herein are polymer mixtures comprising polymers have at least one different non-repeating unit. Methods for making and using the polymer mixtures are also disclosed. Also disclosed are uses of the polymer mixtures, including methods for making microparticles from the polymer mixtures.
C08L 67/04 - Polyesters dérivés des acides hydroxycarboxyliques, p. ex. lactones
C08L 69/00 - Compositions contenant des polycarbonatesCompositions contenant des dérivés des polycarbonates
C08L 71/00 - Compositions contenant des polyéthers obtenus par des réactions créant une liaison éther dans la chaîne principaleCompositions contenant des dérivés de tels polymères
C08G 64/30 - Procédés généraux de préparation utilisant des carbonates
C08G 65/02 - Composés macromoléculaires obtenus par des réactions créant une liaison éther dans la chaîne principale de la macromolécule à partir d'éthers cycliques par ouverture d'un hétérocycle
Described herein are improved microparticles. In one aspect, the microparticles comprise a first polymer and a second polymer wherein the second polymer is different than the first polymer. In further aspects, the microparticles comprise a bioactive agent encapsulated therein.
Disclosed herein are implantable film-based composites, implantable elastic band composites, implantable flexible body composites, implantable suction cup composites, terpolymer compositions, spray coating compositions, methods for using the composites and compositions, and implant devices comprising the composites and compositions.
A61K 31/7036 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine ayant au moins un groupe amino lié directement au carbocycle, p. ex. streptomycine, gentamycine, amikacine, validamycine, fortimicines
92.
AN IMPLANTABLE COMPOSITE COMPRISING A TACKY BIOCOMPATIBLE POLYMER FILM AND A RELEASABLE BIOACTIVE AGENT
Disclosed herein are implantable film-based composites, implantable elastic band composites, implantable flexible body composites, implantable suction cup composites, terpolymer compositions, spray coating compositions, methods for using the composites and compositions, and implant devices comprising the composites and compositions.
A61K 31/7036 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine ayant au moins un groupe amino lié directement au carbocycle, p. ex. streptomycine, gentamycine, amikacine, validamycine, fortimicines
The present disclosure relates to processes for preparing microparticles using an emulsion process where both a solvent and a salt are used in the continuous phase of the emulsion. The present disclosure also relates to microparticles having an angle of repose of ≤ 35, as measured using a Hele-Shaw cell.
A61K 31/573 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne à deux atomes de carbone, p. ex. prégnane ou progestérone substitués en position 21, p. ex. cortisone, dexaméthasone, prednisone ou aldostérone
The present disclosure relates to processes for preparing microparticles using a solvent extraction technique, including controlled addition and/or removal of the extraction phase.
The present disclosure relates to processes for preparing microparticles comprising peptides and to microparticles prepared by such processes. Also disclosed are methods for delivering a bioactive peptide to a subject in need of treatment by the bioactive peptide.
Compositions and methods of making and using of microparticle compositions that provide faster flow or improved injectability through smaller or small-diameter needles have been developed. Notably, the microparticle compositions can be successfully delivered or administered through smaller-diameter needles than other microparticle compositions prepared from biocompatible or biodegradable polymers including, for example, poly(lactide), poly(lactide-co-glycolide), polycaprolactone, or poly- 3-hydroxybutyrate. The microparticle compositions can exhibit a higher solids loading for a given needle size and/or faster flow through needles than other microparticle compositions. Further, blending or mixing the polymer of the microparticle composition with other polymer formulations can enhance the injectability of the resulting formulation.
Disclosed herein are biocompatible and biodegradable polymers comprising one or more ECM-mimetic peptides and one or more biodegradable moieties, wherein the moieties do not comprise an amino acid or residue thereof. Further disclosed herein are methods for making and using the disclosed biocompatible polymers.
The disclosed processes for forming microparticles utilize low volumes of processing water while still providing microparticles having low residual solvent levels. The processes are adaptable to both continuous and batch processes using oil/water or water/oil or water/oil/water or oil/water/oil emulsions.
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
B29C 39/10 - Moulage par coulée, c.-à-d. en introduisant la matière à mouler dans un moule ou entre des surfaces enveloppantes sans pression significative de moulageAppareils à cet effet pour la fabrication d'objets de longueur définie, c.-à-d. d'objets séparés en incorporant des parties ou des couches préformées, p. ex. coulée autour d'inserts ou sur des objets à recouvrir
99.
Precipitated silica for thickening and creating thixotropic behavior in liquid systems
2, and a modified tapped density of less than or equal to 70 g/l is useful for thickening and providing thixotropy in liquid systems and shows superior efficiency at thickening and creating thixotropy compared to existing grades of precipitated silica. The precipitated silica functions best as a thixotrope in non-polar or intermediate polar liquid systems such as unsaturated polyester (UPE) resin systems.
B05D 3/00 - Traitement préalable des surfaces sur lesquelles des liquides ou d'autres matériaux fluides doivent être appliquésTraitement ultérieur des revêtements appliqués, p. ex. traitement intermédiaire d'un revêtement déjà appliqué, pour préparer les applications ultérieures de liquides ou d'autres matériaux fluides
B60C 1/00 - Pneumatiques caractérisés par la composition chimique, la disposition ou le mélange physique de la composition
B02C 19/06 - Appareils utilisant un courant de fluides
B02C 19/00 - Autres dispositifs ou procédés de désagrégation
B32B 9/04 - Produits stratifiés composés essentiellement d'une substance particulière non couverte par les groupes comprenant une telle substance comme seul composant ou composant principal d'une couche adjacente à une autre couche d'une substance spécifique
B32B 5/16 - Produits stratifiés caractérisés par l'hétérogénéité ou la structure physique d'une des couches caractérisés par le fait qu'une des couches est formée de particules, p. ex. de copeaux, de fibres hachées, de poudre
Disclosed are terpolymer compositions of lactide, glycolide, and caprolactone and methods of making such polymers with an initiator. Methods of using the terpolymers as a drug delivery platform are also disclosed.