The invention relates to biocompatible polymer gel compositions useful in facilitating and maintaining hemostasis. The biocompatible polymeric gel composition is comprised of (a) one or more than one polyanionic polymer, (b) one or more than one polycationic polymer, and (c) a solvent. A preferred composition includes sodium alginate, chitosan, and water to produce an adhesive hemostatic device that is useful in facilitating and maintaining rapid hemostasis.
A61L 26/00 - Aspects chimiques des bandages liquides ou utilisation de matériaux pour les bandages liquides
A61L 15/22 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux macromoléculaires
A61L 15/42 - Utilisation de matériaux caractérisés par leur fonction ou leurs propriétés physiques
The invention relates to biocompatible polymer gel compositions useful in facilitating and maintaining hemostasis. The biocompatible polymeric gel composition is comprised of (a) one or more than one polyanionic polymer, (b) one or more than one polycationic polymer, and (c) a solvent. A preferred composition includes sodium alginate, chitosan, and water to produce an adhesive hemostatic device that is useful in facilitating and maintaining rapid hemostasis.
A61L 26/00 - Aspects chimiques des bandages liquides ou utilisation de matériaux pour les bandages liquides
A61L 15/22 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux macromoléculaires
A61L 15/42 - Utilisation de matériaux caractérisés par leur fonction ou leurs propriétés physiques
A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.
A61K 31/195 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
8.
In-situ cross-linkable polymeric compositions and methods thereof
A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Medical preparations to treat wounds and to stop bleeding; hemostat, namely, bio-material preparations in the nature of tissue adhesives, tissue sealants, hydrogels, films, barriers, adhesion prevention materials, spray adhesive materials for control of profuse bleeding for medical use.
10.
In-situ cross-linkable polymeric compositions and methods thereof
A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
(1) A full line of medicated and pharmaceutical preparations, namely preparations to treat wounds and to stop bleeding, both prescription and over-the-counter, for use in connection with humans and animals; Wound dressings, namely, rolled gauze, gauze pads, non-stick gauze pads, bandages, and adhesive pads; topical dressings and applicator therefor for treatment of wounds, namely, minor cuts, lacerations, abrasions, severely bleeding wounds, puncture wounds, surgical wounds, skin grafts and burns; absorbable hemostat in the nature of biological materials for control of profuse bleeding; natural and synthetic polymers for use in general surgery; biological adhesive for surgical and clinical use; chemical preparations that aid in the coagulation of blood for human and veterinary medicinal use, and delivery mechanism sold as a unit therewith; hemostatic agents in the nature of granules, powders, liquids, gels, sheets and fibers used for treating wounds; wound dressings; bandages for dressings; sponges for wound, burn, and surgery dressings; gauze; first aid kits
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
A full line of medicated and pharmaceutical preparations, both prescription and over-the-counter, for use in connection with humans and animals; Wound dressings, namely, rolled gauze, gauze pads, non-stick gauze pads, bandages, and adhesive pads; topical dressings and applicator therefor for treatment of wounds, namely minor cuts, lacerations, abrasions, severely bleeding wounds, puncture wounds, surgical wounds, skin grafts and burns; absorbable hemostat for control of profuse bleeding; natural and synthetic polymers for use in general surgery; biological adhesive for surgical and clinical use; chemicals and delivery mechanism that aid in the coagulation of blood for human and veterinary medicinal use sold as a unit therewith; hemostatic agents in the nature of granules, powders, liquids, gels, sheets and fibers used for treating wounds; wound dressings; bandages for dressings; sponges for dressings; gauze; first aid kits.
The invention relates to biocompatible compositions comprising solid particles of chitosan dispersed in an aqueous solution of sodium alginate for use in hemostasis. The biocompatible compositions provide (a) advantageous fluidity which allows the composition to conform to the site of injury better than solid compositions; (b) mechanical advantages arising from the weight of the solid particles; and (c) improved cell adhesion/aggregation.
A61L 15/22 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux macromoléculaires
The invention relates to biocompatible polymer gel compositions useful in facilitating and maintaining hemostasis. The biocompatible polymeric gel composition is comprised of (a) one or more than one polyanionic polymer, (b) one or more than one polycationic polymer, and (c) a solvent. A preferred composition includes sodium alginate, chitosan, and water to produce an adhesive hemostatic device that is useful in facilitating and maintaining rapid hemostasis.
A61L 15/22 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux macromoléculaires
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Medical preparations to treat wounds and to stop bleeding; hemostat, namely, bio-material preparations in the nature of tissue adhesives, tissue sealants, hydrogels [ films, barriers, adhesion prevention materials, spray adhesive materials ] for control of profuse bleeding for medical use
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
topical dressings and applicator therefor for treatment of wounds, namely, minor cuts, lacerations, abrasions, severely bleeding wounds, puncture wounds, surgical wounds, skin grafts and burns; absorbable hemostat in the nature of biological materials for control of profuse bleeding; natural and synthetic polymers for use in general surgery; biological adhesive for surgical and clinical use; chemical preparations that aid in the coagulation of blood for human and veterinary medicinal use, and delivery mechanism sold as a unit therewith; hemostatic agents in the nature of liquids, and gels used for treating wounds; wound dressings
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
(1) Veterinary preparations, namely, bio-material preparations in the nature of tissue adhesives, tissue sealants, hydrogels, films, barriers, adhesion prevention materials, spray adhesive materials for control of profuse bleeding; absorbable hemostat for control of profuse bleeding for use by veterinarians
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Medical preparations to treat wounds and to stop bleeding of animals for use by veterinarians; absorbable hemostat for control of profuse bleeding for use by veterinarians, none of the aforesaid for use on or in connection with products or services outside the veterinarian field.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Medical preparations to treat wounds and to stop bleeding of animals for use by veterinarians; absorbable hemostat, namely, bio-material preparations in the nature of hydrogels for control of profuse bleeding for use by veterinarians, none of the aforesaid for use on or in connection with products or services outside the veterinarian field
