The invention relates to biocompatible polymer gel compositions useful in facilitating and maintaining hemostasis. The biocompatible polymeric gel composition is comprised of (a) one or more than one polyanionic polymer, (b) one or more than one polycationic polymer, and (c) a solvent. A preferred composition includes sodium alginate, chitosan, and water to produce an adhesive hemostatic device that is useful in facilitating and maintaining rapid hemostasis.
A61L 26/00 - Chemical aspects of, or use of materials for, liquid bandages
A61L 15/22 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
A61L 15/42 - Use of materials characterised by their function or physical properties
The invention relates to biocompatible polymer gel compositions useful in facilitating and maintaining hemostasis. The biocompatible polymeric gel composition is comprised of (a) one or more than one polyanionic polymer, (b) one or more than one polycationic polymer, and (c) a solvent. A preferred composition includes sodium alginate, chitosan, and water to produce an adhesive hemostatic device that is useful in facilitating and maintaining rapid hemostasis.
A61L 26/00 - Chemical aspects of, or use of materials for, liquid bandages
A61L 15/22 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
A61L 15/42 - Use of materials characterised by their function or physical properties
A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.
A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Medical preparations to treat wounds and to stop bleeding; hemostat, namely, bio-material preparations in the nature of tissue adhesives, tissue sealants, hydrogels, films, barriers, adhesion prevention materials, spray adhesive materials for control of profuse bleeding for medical use.
10.
In-situ cross-linkable polymeric compositions and methods thereof
A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) A full line of medicated and pharmaceutical preparations, namely preparations to treat wounds and to stop bleeding, both prescription and over-the-counter, for use in connection with humans and animals; Wound dressings, namely, rolled gauze, gauze pads, non-stick gauze pads, bandages, and adhesive pads; topical dressings and applicator therefor for treatment of wounds, namely, minor cuts, lacerations, abrasions, severely bleeding wounds, puncture wounds, surgical wounds, skin grafts and burns; absorbable hemostat in the nature of biological materials for control of profuse bleeding; natural and synthetic polymers for use in general surgery; biological adhesive for surgical and clinical use; chemical preparations that aid in the coagulation of blood for human and veterinary medicinal use, and delivery mechanism sold as a unit therewith; hemostatic agents in the nature of granules, powders, liquids, gels, sheets and fibers used for treating wounds; wound dressings; bandages for dressings; sponges for wound, burn, and surgery dressings; gauze; first aid kits
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
A full line of medicated and pharmaceutical preparations, both prescription and over-the-counter, for use in connection with humans and animals; Wound dressings, namely, rolled gauze, gauze pads, non-stick gauze pads, bandages, and adhesive pads; topical dressings and applicator therefor for treatment of wounds, namely minor cuts, lacerations, abrasions, severely bleeding wounds, puncture wounds, surgical wounds, skin grafts and burns; absorbable hemostat for control of profuse bleeding; natural and synthetic polymers for use in general surgery; biological adhesive for surgical and clinical use; chemicals and delivery mechanism that aid in the coagulation of blood for human and veterinary medicinal use sold as a unit therewith; hemostatic agents in the nature of granules, powders, liquids, gels, sheets and fibers used for treating wounds; wound dressings; bandages for dressings; sponges for dressings; gauze; first aid kits.
The invention relates to biocompatible compositions comprising solid particles of chitosan dispersed in an aqueous solution of sodium alginate for use in hemostasis. The biocompatible compositions provide (a) advantageous fluidity which allows the composition to conform to the site of injury better than solid compositions; (b) mechanical advantages arising from the weight of the solid particles; and (c) improved cell adhesion/aggregation.
A61L 15/22 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
The invention relates to biocompatible polymer gel compositions useful in facilitating and maintaining hemostasis. The biocompatible polymeric gel composition is comprised of (a) one or more than one polyanionic polymer, (b) one or more than one polycationic polymer, and (c) a solvent. A preferred composition includes sodium alginate, chitosan, and water to produce an adhesive hemostatic device that is useful in facilitating and maintaining rapid hemostasis.
A61L 15/22 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Medical preparations to treat wounds and to stop bleeding; hemostat, namely, bio-material preparations in the nature of tissue adhesives, tissue sealants, hydrogels [ films, barriers, adhesion prevention materials, spray adhesive materials ] for control of profuse bleeding for medical use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
topical dressings and applicator therefor for treatment of wounds, namely, minor cuts, lacerations, abrasions, severely bleeding wounds, puncture wounds, surgical wounds, skin grafts and burns; absorbable hemostat in the nature of biological materials for control of profuse bleeding; natural and synthetic polymers for use in general surgery; biological adhesive for surgical and clinical use; chemical preparations that aid in the coagulation of blood for human and veterinary medicinal use, and delivery mechanism sold as a unit therewith; hemostatic agents in the nature of liquids, and gels used for treating wounds; wound dressings
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Veterinary preparations, namely, bio-material preparations in the nature of tissue adhesives, tissue sealants, hydrogels, films, barriers, adhesion prevention materials, spray adhesive materials for control of profuse bleeding; absorbable hemostat for control of profuse bleeding for use by veterinarians
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Medical preparations to treat wounds and to stop bleeding of animals for use by veterinarians; absorbable hemostat for control of profuse bleeding for use by veterinarians, none of the aforesaid for use on or in connection with products or services outside the veterinarian field.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Medical preparations to treat wounds and to stop bleeding of animals for use by veterinarians; absorbable hemostat, namely, bio-material preparations in the nature of hydrogels for control of profuse bleeding for use by veterinarians, none of the aforesaid for use on or in connection with products or services outside the veterinarian field
