Embodiments of the present disclosure relate to a flexible device. The flexible device includes a flexible sensing slice. The flexible sensing slice includes: a combination of an ultrasound sensor and at least one bioelectrical sensor. The at least one bioelectrical sensor is fabricated by processing a polyimide film using a laser with Laser-Induced Graphene (LIG) as a sensing material, and the ultrasound sensor is placed on the polyimide film. The flexible sensing slice further includes: a Polydimethylsiloxane (PDMS) film encapsulating the combination of the ultrasound sensor and the at least one bioelectrical sensor.
A computer-based method of pre-training a graph neural network for molecular graphs is provided. The method includes assigning a weight to each atom in a molecule of a molecular sample based at least on a number of atoms of each atomic type in the molecule, an atomic composition of the molecular sample is known, randomly masking a number of atoms in the molecule of the molecular sample based on the assigned weight of each atom, an atomic type having a higher number of atoms in the molecule has a lower probability of being masked, and pre-training the graph neural network using the masked molecular sample.
A battery equalizer for a series-connected battery string. The battery equalizer contains a plurality of cell circuits, an AC link, and a DC/AC converter. The plurality of cell circuits at their input ends is connected in parallel with each other and to the AC link. Each cell circuit at its output end is adapted to connect to a corresponding battery cell of the battery string. The DC/AC converter connects to the AC link. Each of the cell circuits contains an AC/DC converter, and an AC side of the AC/DC converter is capacitively-coupled to the AC link at the input end of the cell circuit. As the current taken from the first stage is common to all battery cells, charging or discharging of individual battery cells is autonomously determined by the output current of the second stage.
A method for preparing a dry facial mask, comprising the steps: using water-soluble polymer, surfactant, ingredients comprising Chinese medicine to form a stock solution; electro-spinning the stock solution onto a substrate to form an intermediate facial mask; and drying the intermediate facial mask to form dry facial mask.
A61K 8/30 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques
A61K 8/72 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques macromoléculaires
A45D 44/00 - Autres articles cosmétiques ou de toilette, p. ex. pour salons de coiffure
A61Q 19/00 - Préparations pour les soins de la peau
IMPERIAL COLLEGE INNOVATIONS LIMITED (Royaume‑Uni)
CITY UNIVERSITY OF HONG KONG (Chine)
Inventeur(s)
Long, Nicholas
Sheppard, Stephanie
Zhu, Zonglong
Li, Zhen
Abrégé
A photovoltaic cell comprising a perovskite layer (110), an electron transporting layer (106) and an interface layer (108) disposed between the electron transporting layer and the perovskite layer. The interface layer comprises a metallocene substituted with a substituent having an O, S, N or P group, for example ferrocene substituted with a thienyl-carboxylate group.
H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
The present disclosures relate to the establishment of a plasmid-based reverse genetic system for TiLV and use of the system to rescue recombinant and reporter TiLVs. The present disclosures also relate to the plasmids used for the rescue of TiLV and the recombinant and reporter TiLVs generated using the methods disclosed herein.
The present invention relates to a method for preparing a dry facial mask, comprising the following steps: dissolving a water-soluble polymer into water to form a first solution; adding surfactant into said first solution and then mixing them until dissolved to form a second solution; adding ingredients comprising Chinese medicine into said second solution, and then mixing them until dissolved to form a stock solution; electro-spinning said stock solution onto a substrate to form an intermediate facial mask; and drying said intermediate facial mask to form said dry facial mask.
PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (Chine)
CITY UNIVERSITY OF HONG KONG (Chine)
Inventeur(s)
Peng, Xianhua
Zhou, Xiang
Xiao, Bo
Abrégé
Disclosed in the present application are a data processing method, apparatus and device, and a computer-readable storage medium. The method comprises: using a policy network, a value function network and a tail risk network that are to be trained to interact with an environment for multiple times, so as to obtain a feedback sample set; using the feedback sample set to separately perform at least one round of training on the policy network, the value function network and the tail risk network; and after each network has undergone at least one round of training and a preset training finish condition being satisfied has been detected, obtaining a trained policy network, so as to adjust hedging portfolios of financial derivatives on the basis of the policy network.
Methods for treating a cytokine storm in a subject in need thereof, the method comprising: administering a therapeutically effective amount of a therapeutic selected from the group consisting of (+)-(S)-2-(6-methoxynaphthalen-2-yl) propanoic acid, acetylsalicylic acid, dexamethasone, azathioprine and pharmaceutically acceptable salts thereof to the subject, wherein the cytokine storm is associated with an Acinetobacter baumannii infection in the subject.
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61P 37/06 - Immunosuppresseurs, p. ex. médicaments pour le traitement du rejet de greffe
Carbon footprint optimization of an electric vehicle, such as a heavy-duty e-truck, traveling in a trip across a highway network subject to a hard deadline constraint and one or more battery state-of-charge (SoC) constraints is carried out by co-determining a route plan, a speed plan and an intermediary charging plan for the electric vehicle with an objective of minimizing a carbon footprint incurred in the trip. In co-determining the three plans, a stage-expanded graph for modeling possible routing decisions of routing the trip in the highway network and possible charging decisions of charging the electric vehicle during the trip is constructed. The stage-expanded graph embeds information of arrival time and arrival SoC to facilitate modeling the charging decisions. The three plans are optimized by a dual subgradient method according to the stage-expanded graph under the objective of minimizing the carbon footprint while satisfying the constraints.
G01C 21/34 - Recherche d'itinéraireGuidage en matière d'itinéraire
11.
Classification of Cognitively Normal Condition, Mild Cognitive Impairment and Alzheimer's Disease Based on Convolutional Neural Networks with Attention Mechanism
An image processing framework for multi-class classifying a subject into cognitive normal, mild cognitive impairment and Alzheimer's disease (AD) conditions is developed. In one realization of the framework, an AD_Net model, which is an attention-enhanced convolution neural network (CNN) formed by embedding a Convolutional Block Attention Module (CBAM) into a CNN having a Visual Geometry Group 19 (VGG19) architecture, processes an image volume of the subject's brain to generate a plurality of AD_Net feature maps and a first plurality of scores that predict respective likelihoods of the three conditions. To enhance the prediction accuracy, a multilayer perception model formed with a plurality of fully connected layers processes the plurality of AD_Net feature maps and a plurality of influencing factors of AD, such as age, gender, geriatric depression scale score, Mini-Mental State Examination score and clinical dementia rating score, to generate a second plurality of scores that predict the respective likelihoods.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
12.
HIERARCHICAL CORE-SATELLITE PARTICLES AND METHODS OF PREPARATION THEREOF
A method of preparing hierarchical core-satellite particles, the method comprising: contacting charged microparticles comprising a first charge, charged nanoparticles comprising a second charge, and a charged binding material selected from the group consisting of charged small molecules and charged polymers, wherein the charged small molecules or the charged polymers comprise a third charge in a solvent thereby forming the hierarchical core-satellite particles, wherein the first charge and the second charge are both positively charged or negatively charged, the third charge is the opposite charge of the first charge and the second charge, and the average size of the charged microparticles is at least about 103 times larger than the average size of the charged nanoparticles.
B01J 13/10 - Coacervation complexe, c.-à-d. interaction de particules de charges de signes opposés
B01J 13/00 - Chimie des colloïdes, p. ex. production de substances colloïdales ou de leurs solutions, non prévue ailleursFabrication de microcapsules ou de microbilles
13.
COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING NEUROPATHIC PAIN
Disclosed is a novel compound 5-(3,4-difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263, Compound 1), its derivatives, composition comprising the compound and method to effectively relieve nerve injury-induced neuropathic pain. Also disclosed are methods of treating diseases or disorders associated with the voltage-gated sodium channels. The disclosed methods may be utilized to treat diseases or disorders associated with pain in a subject, including nociceptive pain, chronic pain, neuropathic pain, and inflammatory pain. Also disclosed are inhibitors that specifically inhibit voltage-gated sodium channel function in a state-dependent manner. The disclosed compounds may also be used in pharmaceutical compositions and methods for treatment of pain associated with voltage-gated sodium channel activity.
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
A method for isolating a circulating tumor cell (CTC) in a sample comprising the CTC or suspected of comprising the CTC, the method including: incubating the sample with immuno-microparticles thereby forming cell and microparticle aggregates (CPAs) in an incubation solution, wherein the average size of the CPAs is larger than 10 μm; and isolating the CPAs with a size-based isolation method thereby forming an isolated CTC, wherein the immuno-microparticles comprise one or more first antibodies conjugated to microparticles, wherein the one or more first antibodies specifically bind to one or more markers of the CTC.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
HONG KONG CENTRE FOR CEREBRO-CARDIOVASCULAR HEALTH ENGINEERING LIMITED (Chine)
Inventeur(s)
Pan, Fei
Wu, Yutong
Sun, Dong
Chan, Hon-Fu Raymond
Cui, Kangning
Abrégé
In cell instance segmentation of an original cell image obtained by microscopy, the original cell image is rotated by a rotation angle to yield a rotated cell image. A first machine-learning model for cell instance segmentation processes the original and rotated cell images such that effectively, horizontal and oblique boxes are used in bounding cells of the original cell image for enhancing cell-segmentation accuracy. A set of predictions is generated for each cell instance identified from the original and rotated cell images, yielding a plurality of sets of predictions for all cell instances. The plurality of sets of predictions is processed to remove any set having predicted space not simply connected, any unwanted set classified by a second machine-learning model as a poor indicator according to a certain performance criterion, and any redundant set. The plurality of sets of predictions then produces a segmentation map for the original cell image.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
G06T 3/60 - Rotation d’images entières ou de parties d'image
G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p. ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersectionsAnalyse de connectivité, p. ex. de composantes connectées
G06V 10/771 - Sélection de caractéristiques, p. ex. sélection des caractéristiques représentatives à partir d’un espace multidimensionnel de caractéristiques
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
16.
BIMETALLIC ALLOY NANOSTRUCTURES FOR EFFICIENT AMMONIA ELECTROSYNTHESIS
Ruthenium-iron nanoflower particles having a plurality of RuFe nanosheets, wherein the plurality of RuFe nanosheets are in a form of a nanoflower useful for the electrochemical synthesis of ammonia; an electrode including the RuFe nanoflower particles; and methods of preparation and use thereof.
Method of reducing carbon dioxide to form one or more hydrocarbon products, the method comprising: providing an electrochemical cell comprising: a working electrode comprising a copper composite comprising a copper nanosheet array comprising a plurality of copper nanosheets, wherein the plurality of copper nanosheets comprise copper(100) facets; a counter electrode; optionally a reference electrode; and an electrolyte solution comprising an electrolyte and CO2, wherein the electrolyte solution is between and in contact with the working electrode, the counter electrode, and optionally the reference electrode; and applying an electric current between the working electrode and the counter electrode resulting in electrolytic reduction of the CO2 thereby forming the one or more hydrocarbon products.
An AZB detection method for video coding, which includes the steps of detecting if a residual signal includes a spatial domain GAZB; detecting if the residual signal includes a frequency domain GAZB if no spatial domain GAZB is detected in the previous step; detecting if the residual signal includes a PAZB if no frequency domain GAZB is detected in the previous step; and determining that the residual signal is a non-AZB signal if no PAZB is detected in the previous step. The proposed method achieves promising time savings for test sequences of different resolutions, with negligible rate-distortion performance loss.
H04N 19/176 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant le codage adaptatif caractérisés par l’unité de codage, c.-à-d. la partie structurelle ou sémantique du signal vidéo étant l’objet ou le sujet du codage adaptatif l’unité étant une zone de l'image, p. ex. un objet la zone étant un bloc, p. ex. un macrobloc
H04N 19/12 - Sélection parmi plusieurs transformées ou standards, p. ex. sélection entre une transformée en cosinus discrète [TCD] et une transformée en sous-bandes ou sélection entre H.263 et H.264
H04N 19/147 - Débit ou quantité de données codées à la sortie du codeur selon des critères de débit-distorsion
H04N 19/18 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant le codage adaptatif caractérisés par l’unité de codage, c.-à-d. la partie structurelle ou sémantique du signal vidéo étant l’objet ou le sujet du codage adaptatif l’unité étant un ensemble de coefficients de transformée
H04N 19/60 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant un codage par transformée
A centimeter-resolution integrated photonic millimeter-wave (mmWave) radar chip operating in the mmWave V band based on a 4-inch wafer-scale thin-film lithium niobate (TFLN) technology is provided. The fabricated TFLN photonic mmWave integrated circuit has a first electro-optic modulator (EOM) capable of generating a broadband linear frequency modulated mmWave radar waveform through optical frequency multiplication of a low-frequency input signal, and a second EOM for frequency de-chirp of the reflected echo wave, thereby greatly relieving bandwidth requirements for the digital-to-analog converter in the transmitter and analog-to-digital converter in the receiver. In the absence of optical and electrical filters, the radar chip features continuous on-demand tunability of the center frequency and bandwidth, currently only limited by the bandwidths of electrical amplifiers. The radar chip provides a promising way to achieve high resolution sensing and detection for vehicle radar, airborne radar, and smart home in the 6G era.
A wireless sensing method and systems based on compressed beamforming reports (CBR) are provided. The method includes performing channel sounding and transmit (TX) beamforming; performing sniffing or extracting information from Wi-Fi traffic; and performing multi-path estimation. The performing multi-path estimation includes performing multi-path modeling with CBR to analyze relationship between signal propagation characteristics and information in CBR by modeling a multi-path channel based on uplink and downlink steering matrices. The performing multi-path modeling with CBR includes performing multi-path modeling with CBR from physical paths to channel state information (CSI) and subsequently from CSI to CBR. The performing multi-path estimation further includes performing maximum likelihood multi-path estimation. The performing maximum likelihood multi-path estimation includes analyzing multi-path fingerprint in CBR, performing fingerprint matching, and performing maximum-likelihood estimation (MLE)-based multi-path reconstruction.
H04B 7/06 - Systèmes de diversitéSystèmes à plusieurs antennes, c.-à-d. émission ou réception utilisant plusieurs antennes utilisant plusieurs antennes indépendantes espacées à la station d'émission
Method of treating a nerve injury in a subject in need thereof, the method comprising: administering a therapeutically effective amount of a therapeutic agent to the subject, wherein the therapeutic agent is selected from the group consisting of metaxalone and a Formin-2 inhibitor, such as an antibody, an antibody fragment, an inhibitory nucleic acid molecule, or a small molecule, wherein the inhibitory nucleic acid molecule substantially silences Fmn2.
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/421 - 1,3-Oxazoles, p. ex. pémoline, triméthadione
A61P 25/02 - Médicaments pour le traitement des troubles du système nerveux des neuropathies périphériques
22.
DEVELOPMENT OF SYNTHETIC PSEUDAMINIC ACID-BASED ANTIBACTERIAL VACCINES AGAINST ACINETOBACTER BAUMANNII
Provided are compositions comprising chemically synthesized pseudaminic acid (Pse) conjugated to a carrier protein using the OPA chemistry, methods of using said compositions to stimulate immune responses in subjects and protect the vaccinated subjects from infections caused by Pse-producing A. baumannii.
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
A61K 39/385 - Haptènes ou antigènes, liés à des supports
A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
The present invention provides an integrated system built on a microfluidics with multiple layers including a cell culture surface and different chambers configured to allow multiple cultivations of a biological agent, formation of three-dimensional multicellular culture model or biofilm, colonization and re-colonization of the biological agent responsive to a stimuli introduced to the integrated system. Such stimuli include physical, chemical and/or biological substance that may affect proliferation, differentiation, and/or function of the biological agent. The biological agent includes a biofilm-forming microbe such as a ubiquitous biofilm-forming bacterial species or biological cells or tissues of a different origin or species such as eukaryotic cells/tissues. The present integrated system can be used in drug screening, establishment of disease model in vitro or in vivo, evaluation of an anti-microbial efficacy, and studying cell-cell interaction.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12Q 1/18 - Test de l'activité antimicrobienne d'un matériau
24.
INTEGRATED SYSTEM FOR MULTIPLE CULTIVATIONS OF A BIOLOGICAL AGENT AND METHODS OF USE THEREOF
An integrated system built on a microfluidics with multiple layers includes a cell culture surface and different chambers configured to allow multiple cultivations of a biological agent, formation of three-dimensional multicellular culture model or biofilm, colonization and re-colonization of the biological agent responsive to a stimuli introduced to the integrated system. Such stimuli include physical, chemical and/or biological substance that may affect proliferation, differentiation, and/or function of the biological agent. The biological agent includes a biofilm-forming microbe such as a ubiquitous biofilm-forming bacterial species or biological cells or tissues of a different origin or species such as eukaryotic cells/tissues. The integrated system can be used in drug screening, establishment of disease model in vitro or in vivo, evaluation of an anti-microbial efficacy, and studying cell-cell interaction.
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
Methods and systems for pre-processing immunocytochemistry images for machine learning are provided. The pre-processing method includes receiving paired positive and negative multi-protein images and segmenting stains of the paired multi-protein images. The method also includes labelling each image pixel corresponding to a cell of the paired multi-protein images and translating image pixel information of the labelled image pixels to tabular form to generate a table of cell coordinates and geometrical characteristics for each of the paired multi-protein images. The method further includes generating two cell-paired tables for each of the paired multi-protein images based on Euclidean distance-based pairing prior to input for the machine learning, where the Euclidean distance-based pairing is based on the cell coordinates in the table of cell coordinates and geometrical characteristics for each of the paired multi-protein images.
Organic-inorganic hybrid perovskite including: M2+, one or more A+, and a multifunctional nonvolatile additive (MNA) comprising a cationic species having the formula R1Ar1R2, wherein M2+ comprises Pb2+, Sn2+, Ge2+, or a mixture thereof; each of the one or more A+ is independently selected from the group consisting of Cs+, Rb+, CH3NH3+, CH3CH2NH3+, H(C═NH2)NH2+, and Me(C═NH2)NH2+; Ar1 is an optionally substituted aryl or an optionally substituted heteroaryl; R1 is —COOH, —CH2COOH, —CH2CH2COOH, —SO3H, —CH2SO3H, —CH2CH2SO3H, —PO3H2, —CH2PO3H2, or —CH2CH2PO3H2; and R2 is —NH(C═NH2)NH2+ or —N(R)3H+, wherein R for each instance is independently hydrogen or C1-C6 alkyl, with the proviso that the one or more A+ includes H(C═NH2)NH2+.
Method of at least partially inhibiting the function of Klebsiella pneumoniae carbapenemase-2 (KPC-2) or a variant thereof, the method including contacting the KPC-2 with a benzoxaborole selected from the group consisting of 5-chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, and mixtures thereof useful in the treatment of beta-lactam antibiotic resistant bacteria infections in a subject.
A61K 31/407 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des systèmes hétérocycliques, p. ex. kétorolac, physostigmine
There is provided a robot comprising an aerial unit, a passive leg mechanism operably coupled with the aerial unit, and a controller. The controller is configured to control operation of the aerial unit such that the robot is operable in, at least, a flight mode and a hopping mode.
A sweat extraction and monitoring system comprises a triboelectric nanogenerator (TENG) for inducing localized sweating for a human skin to generate sweat, iontophoresis electrodes electrically connected to the TENG and configured to be operably electrically contacting the human skin, at least one microfluidic channel for receiving the sweat, at least one biosensor for sensing the sweat received in the at least one microfluidic channel, and at least one sweat-activated battery configured to be actuatable by the sweat for powering the at least one biosensor.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
Ternary heterostructure comprising Ni2P, MoNiP2, and MoP, wherein the ternary heterostructure comprises crystalline regions and amorphous regions useful as an electrocatalyst for alkaline hydrogen evolution reaction; a cathode and an electrochemical cell including the same; and methods of preparation and use thereof.
C25B 11/091 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques
Similarity-based deformable registration of medical images that contain tumor regions often undesirably leads to disproportionate volume changes to tumor regions. An image-registration framework for preserving tumor volumes while promoting similarity in non-tumor part is provided. The framework involves a two-stage process. In the first stage, similarity-based registration is used to identify potential tumor regions by their volume change, generating a soft tumor mask accordingly. In the second stage, a volume-preserving registration network is used. The network uses a novel adaptive volume-preserving loss that penalizes the change in size adaptively based on the masks calculated from the previous stage. The framework balances image similarity and volume preservation in different regions, i.e. non-tumor and tumor regions, by using soft tumor masks to adjust the imposition of volume-preserving loss on each one. It ensures that the tumor volumes are preserved during the registration process.
A general method for synthesizing a series of novel amorphous-crystalline palladium (Pd) -based heterophase nanocatalysts for various promising electrocatalytic applications. The synthesized amorphous-crystalline Pd-PdAu core-island nanocatalyst exhibits high activity, fast reaction kinetics, and excellent long-term catalytic stability toward glycerol oxidation reaction (GOR). Remarkably, the main product of glycerol catalyzed by amorphous-crystalline Pd-PdAu core-island heterostructure is glyceric acid, which possesses the highest commercial value among all the GOR products. The one-pot synthesized amorphous-crystalline Pd-PdPt Janus heterostructure shows remarkable catalytic activity, and fast reaction kinetics towards formic acid oxidation reaction (FOR) in alkaline solution in comparison with commercial Pt/C catalyst and amorphous Pd nanoparticles (NPs), which benefits the development of advanced electrocatalysts for practical applications. The synthesized amorphous-crystalline PdCu Janus heterostructures with bcc phase exhibit high activity, fast reaction kinetics, and excellent long-term catalytic stability for hydrogen evolution reaction (HER) and 5-hydroxymethylfurfural oxidation reaction (HMFOR), benefiting the development of advanced electrocatalysts for practical applications.
B22F 9/24 - Fabrication des poudres métalliques ou de leurs suspensionsAppareils ou dispositifs spécialement adaptés à cet effet par un procédé chimique avec réduction de mélanges métalliques à partir de mélanges métalliques liquides, p. ex. de solutions
33.
A PHOTOELECTROCHEMICAL CELL AND A PHOTOELECTROCHEMICAL LITHIUM EXTRACTION DEVICE BASED ON THE SAME
The present invention provides a photoelectrochemical (PEC) cell and a lithium extraction device based on same. The PEC cell comprises: a substrate having a first surface and a second surface opposite to the first surface; a photo-absorber disposed on the first surface of the substrate; a protective layer disposed on the second surface of the substrate; and a catalyst layer disposed on the protective layer. The photo-absorber is spatially and functionally decoupled from the catalyst layer through the substrate to avoid the blocking of light to be absorbed by the photo-absorber caused by the shadowing effect of co-catalysts or gas products before it reaches the photo-absorber. Combining the decoupled PEC cell and Li-ion selective membrane, high-purity green Li is successfully extracted from seawater for the first time while storing solar energy as hydrogen energy with high efficiency.
H01L 31/0256 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par les matériaux
H01L 31/0735 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV] caractérisés par au moins une barrière de potentiel ou une barrière de surface les barrières de potentiel étant uniquement du type PN à hétérojonction comprenant uniquement des composés semiconducteurs AIIIBV, p.ex. cellules solaires en GaAs/AlGaAs ou InP/GaInAs
The present invention relates to a method for preparing polymer film, comprising the following steps: i) forming at least one polymer as a first membrane by electrospinning; ii) forming a first mixture by dispersing at least one mid-infrared radiation reflective material into a first liquid; iii) filtering said first mixture, wherein said first membrane is used as a filter membrane, thereby depositing said at least one mid-infrared radiation reflective material on said first membrane to form a second membrane, and iv) drying said second membrane to form a third membrane; characterized in that, said at least one polymer is selected from polyvinylidene fluoride and/or polyurethane.
D01D 5/00 - Formation des filaments, fils ou similaires
D01F 6/12 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir d'homopolymères obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone à partir de polymères d'hydrocarbures halogénés à partir de polymères d'hydrocarbures fluorés
D01F 6/70 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de produits d'homopolycondensation à partir de polyuréthanes
D04H 1/413 - Non-tissés formés uniquement ou principalement de fibres coupées ou autres fibres similaires relativement courtes à partir de voiles ou couches composés de fibres ne possédant pas des propriétés cohésives réelles ou potentielles contenant des granulés autres que les substances absorbantes
D04H 1/728 - Non-tissés formés uniquement ou principalement de fibres coupées ou autres fibres similaires relativement courtes caractérisés par la méthode de formation des voiles ou couches, p. ex. par la réorientation des fibres les fibres étant disposées au hasard par électrofilage
D06M 11/74 - Traitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du carbone ou ses composés avec du carbone ou du graphiteTraitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du carbone ou ses composés avec des carburesTraitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du carbone ou ses composés avec des acides graphitiques ou leurs sels
D06M 101/22 - Polymères ou copolymères de mono-oléfines halogénées
35.
DEEP LEARNING-BASED APPROACH FOR SOLVING OPTIMAL POWER FLOW PROBLEMS WITH FLEXIBLE TOPOLOGY
A method for solving multiple OPF equations of an AC electrical power system with plural topologies and admittances is provided. The method includes determining a continuous admittance space to embed the plural topologies, determining a plurality of voltage magnitudes and a plurality of voltage phase angles of the plurality of buses by a deep neural network, and reconstructing an active power generation and a reactive power generation using power flow equations according to the plurality of voltage magnitudes, the plurality of voltage phase angles, and the load inputs. The continuous admittance space is an admittance matrix of a plurality of line admittances each having a default admittance computed using a conductance and a susceptance of the plurality of branches. The deep neural network receives the load inputs and the plurality of line admittances as inputs.
H02J 3/16 - Circuits pour réseaux principaux ou de distribution, à courant alternatif pour règler la tension dans des réseaux à courant alternatif par changement d'une caractéristique de la charge du réseau par réglage de puissance réactive
There is provided a method for autoregressive based compression of a dataset with a plurality of data units, comprising using a neural network based probability estimator, determining a probability associated with a target data unit based on one or more previous data units associated with the target data unit, and using a coder, coding the target data unit based on the target data unit and the determined probability associated with the target data unit.
222- related conversion techniques. The 2H Au nanomaterials possess unique optical properties compared with their 3C counterparts. The lifetime of plasmonic hot carriers in 2H Au square nanosheets is much longer than that in 3C Au square nanosheets, indicating 2H Au square nanosheets may be promising materials for optoelectronic applications.
A microfluidic device (10), comprising a blood sample inlet (12), a separation membrane (14), a manifold inlet (16) in fluid communication with the blood sample inlet (12) at a joint (18), a capillary pump (22) in fluid communication with the joint (18) and located downstream of the joint (18), and a vent hole (24) in fluid communication with the capillary pump (22). The separation membrane (14) comprises a top layer (28) adjacent to the sample inlet (12) and a bottom layer (30) distant from the sample inlet (12). The top layer (28) has an average pore size ranging from about 1 μm to about 50 μm. The bottom layer (30) has an average pore size ranging from about 0.05 μm to about 20 μm. The separation membrane (14) is arranged between the blood sample inlet (12) and the joint (18).
A shape memory ceramic is provided. The shape memory ceramic comprises a first portion and a second portion. The first and second portions of the shape memory ceramic are bonded, and the shape memory ceramic is elastomer-derived ceramic comprising silicon oxycarbide. The first portion of the shape memory ceramic is treated with ultraviolet ozone, and the second portion of the shape memory ceramic is free from treatment of ultraviolet ozone. The manufacturing and 4D printing methods of the shape memory ceramic are also provided.
B29C 64/135 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective caractérisés par la source d'énergie à cet effet, p. ex. par irradiation globale combinée avec un masque la source d’énergie étant concentrée, p. ex. lasers à balayage ou sources lumineuses focalisées
B33Y 80/00 - Produits obtenus par fabrication additive
C04B 35/00 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques
40.
Polypeptide and its use as a CCK receptor agonist/antagonist
Centre for Regenerative Medicine & Health, Hong Kong Institute of Science & Innovation, Chinese (Chine)
City University of Hong Kong (Chine)
Inventeur(s)
Tortorella, Mickey Daniel
He, Jufang
Abrégé
The present invention relates to the field of chemical and pharmaceutical technologies, in particular to a polypeptide and its use as a CCK receptor agonist/antagonist. Experiments show that the polypeptide provided by the present invention has a high agonistic/antagonistic activity on CCK receptors. Compared with the polypeptide CCK4, the polypeptide according to the present invention has a longer half-life and duration of efficacy in vivo. Experiments show that the polypeptide according to the present invention produces a significant improvement on the spatial memory deficiency of senile mice, memory-deficient senile mice, and Alzheimer's mice, and thus has a great application potential.
C10M 173/02 - Compositions lubrifiantes contenant plus de 10% d'eau ne contenant pas d'huiles minérales ou grasses
C10M 177/00 - Méthodes particulières de préparation des compositions lubrifiantesModification chimique par post-traitement des constituants ou de la composition lubrifiante elle-même, non couverte par d'autres classes
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
B82Y 40/00 - Fabrication ou traitement des nanostructures
Viral protease, EV71 2A proand SARS-CoV-2 3CL pro, promote the extracellular level of LRPAP1, which degrades IFNAR1 and inhibits the following interferon signaling. Moreover, inhibiting LRPAP1 by a composition having α2M, siRNA, or other LRPAP1 inhibitors can improve both RNA and DNA viral infections.
A reversible phase transition in the whole semimetallic 1T′-tungsten disulfide (1T′-WS2) is realizable by proton intercalation and deintercalation, resulting in a newly-discovered semiconducting WS2 with a novel unconventional phase, denoted as 1T′d phase. A transport modulation with an on/off ratio of over 106 is realizable during the phase transition from the 1T′-WS2 to 1T′d-WS2. A transistor utilizing the advantage of reversible phase transition is developed by using a 1T′-WS2 nanosheet as a channel layer. A proton electrolyte contacts an edged circumference of the nanosheet for providing a reservoir of protons for proton intercalation and deintercalation of the nanosheet. The proton electrolyte is controllable by a gate-source voltage to intercalate or de-intercalate the nanosheet with protons for inducing a reversible phase transition over the nanosheet to thereby modify an electrical conductance of the channel layer or a spectral response of the channel layer to light.
H10N 70/00 - Dispositifs à l’état solide n’ayant pas de barrières de potentiel, spécialement adaptés au redressement, à l'amplification, à la production d'oscillations ou à la commutation
H10N 70/20 - Dispositifs de commutation multistables, p. ex. memristors
An integrated MWP processing engine based on a thin-film lithium niobate (LN) platform capable of performing computation tasks of analog signals up to 92G samples per second is provided. By integrating a high-speed electro-optic modulation block and a multi-purpose low-loss signal processing section on the same chip fabricated from a 4-inch wafer-scale process, we demonstrate high-speed analog computation, i.e. first- and second-order temporal integration and differentiation with computing accuracies up to 98.1%, and deploy these functions to showcase three proof-of-concept applications, namely, ordinary differential equation solving, ultra-wideband signal generation and high-speed edge detection of images. We further leverage the image edge detector to enable a photonic-assisted image segmentation model that effectively outlines boundaries of melanoma lesion in medical images, achieving orders of magnitude faster processing speed and lower power consumption than conventional electronic processors. Our ultrafast LN MWP engine provides compact, low-power, low-latency and cost-effective solutions.
G02F 1/21 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur par interférence
G02F 1/225 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur par interférence dans une structure de guide d'ondes optique
The present disclosure provides a LAMP-based, one-pot pathogen detection system and method integrating a high specificity assay for identifying true positive samples in an analyte before a whole course of LAMP reaction completes, in order to shorten the reaction time and reduce the likelihood of false positive results due to non-specific amplification or signal error (e.g., sample has too high pH) in the LAMP reaction. The present invention integrates an immunochromatographic assay such as lateral flow assay (LFA) in result interpretation from colorimetric and/or fluorimetric aspects of the LAMP reaction in order to enable a real-time pathogen detection, thereby improving the efficiency thereof with high specificity. The present detection system employs a single reaction system to enable multiple result interpretation, and the LAMP reaction can be carried out in a simple platform capable of generating constant heat.
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
46.
METHODS FOR TREATING HYPERVIRULENT KLEBSIELLA PNEUMONIAE INFECTION
Methods of treating a hypervirulent Klebsiella pneumoniae (hvKp) infection in a subject in need thereof, the method involving co-administering a therapeutically effective amount of an antibiotic and a non-steroidal anti-inflammatory drug or a signal transducer and activator of transcription 1 inhibitor to the subject.
A61K 31/616 - Acide salicyliqueSes dérivés ayant le groupe hydroxyle en position 2 estérifié, p. ex. acide salicylsulfurique par des acides carboxyliques, p. ex. acide acétylsalicylique
A61K 31/341 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à cinq chaînons avec un oxygène comme seul hétéro-atome d'un cycle, p. ex. isosorbide non condensés avec un autre cycle, p. ex. ranitidine, furosémide, bufétolol, muscarine
A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
A61K 31/545 - Composés contenant des systèmes cycliques thia-5 aza-1 bicyclo [4.2.0] octane, c.-à-d. composés contenant un système cyclique de formule , p. ex. céphalosporines, céfaclor, céphalexine
Electrocatalytic overall water splitting to generate hydrogen and oxygen is a green and sustainable approach with zero carbon emission, which is important for the future renewable energy landscape. The practical application of this approach is challenging due to the sluggish reaction kinetics of water activation at high current densities, which are hard to overcome. Although high-performance alkaline bifunctional electrocatalysts may be useful, current catalysts lack both activity and durability. One approach is to rationally design bifunctional two-dimensional (2D) heterostructures but obtaining an efficient and durable catalyst has proved difficult. The present disclosure relates generally to an electrocatalyst including a 2D heterostructure (Ru-CMOP), methods of making and using the same. The catalyst of the present disclosure is designed for high activity and good durability at industrial-level high current densities.
Continuous miniaturization of semiconductor devices is the key to boosting modern electronics development. However, such downscaling strategy has been rarely utilized in photoelectronics and photovoltaics. Here, in this work, a full-vdWs 1D p-Te/2D n-Bi2O2Se heterodiode with a rationally-designed nanoscale ultra-photosensitive channel is reported. Enabled by the dangling bond-free mixed-dimensional vdWs integration, the Te/Bi2O2Se type-II diodes show a high rectification ratio of 3.6×104. Operating with 100 mV reverse bias or in a self-power mode, the photodiodes demonstrated excellent photodetection performances, including high responsivities of 130 A W−1 (100 mV bias) and 768.8 mA W−1 (self-power mode), surpassing most of the reports of other heterostructures. More importantly, a superlinear photoelectric conversion phenomenon is uncovered in these nanoscale full-vdWs photodiodes, in which a model based on the in-gap trap-assisted recombination is proposed for this superlinearity. All these results provide valuable insights in light-matter interactions for further performance enhancement of photoelectronic devices.
H01L 31/109 - Dispositifs sensibles au rayonnement infrarouge, visible ou ultraviolet caractérisés par une seule barrière de potentiel ou de surface la barrière de potentiel étant du type PN à hétérojonction
H01L 31/0336 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, des matériaux semi-conducteurs couverts par plusieurs des groupes dans des régions semi-conductrices différentes, p.ex. des hétéro-jonctions Cu2X/CdX, X étant un élément du groupe VI de la classification périodique
H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
H01L 31/18 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
49.
METHODS FOR PREPARING POLYURETHANE FILM AND FABRICS COMPRISING THE SAME
The present invention discloses a method for preparing a polyurethane film, comprising the steps of: i) dissolving polyurethane into a first solvent to form a first solution; ii) dissolving salt into a second solvent to form a second solution; iii) preparing a spinning stock solution by mixing said first solution and said second solution; iv) spinning said spinning stock solution in an electrospinning device to obtain a polyurethane film; v) providing a container to which a third solvent is sprayed; and vi) arranging said polyurethane film in said container for a period of time.
A method for preparing a polyurethane film, comprising the steps of: i) dissolving polyurethane into a first solvent to form a first solution; ii) dissolving salt into a second solvent to form a second solution; iii) preparing a spinning stock solution by mixing said first solution and said second solution; iv) spinning said spinning stock solution in an electrospinning device to obtain a polyurethane film; v) providing a container to which a third solvent is sprayed; and vi) arranging said polyurethane film in said container for a period of time.
D04H 1/728 - Non-tissés formés uniquement ou principalement de fibres coupées ou autres fibres similaires relativement courtes caractérisés par la méthode de formation des voiles ou couches, p. ex. par la réorientation des fibres les fibres étant disposées au hasard par électrofilage
D04H 1/4382 - Fibres obtenues par étirage de film réticuléFibres compositesFibres mixtesFibres ultrafinesFibres pour cuir artificiel
D01D 5/00 - Formation des filaments, fils ou similaires
51.
Weakly-Supervised 3D Medical Image Segmentation using Geometric Prior and Contrastive Similarity
A weakly-supervised framework for segmenting a three-dimensional (3D) medical image incorporates information of geometric prior and contrastive similarity in a loss-based fashion for enhancing distinguishability of an organ in presence of complex organ shape and image artifacts (e.g., low-contrast tissues) in the image. Training images with bounding-box annotations are used to train the framework. The geometric prior is advantageously built on point-cloud representations, which are much more fine-grained and flexible than volume representations, thus serving as better supervision than an inherent property of the bounding-box annotations (i.e. height and width). Furthermore, using contrastive similarity encourages organ pixels to gather around in a contrastive embedding space. It helps more-effectively distinguish low-contrast tissues from the background than using the conventionally-used gray space.
One embodiment includes a microfluidic chip for implementing cell deformability. The microfluidic chip comprises an inlet configured to receive cells, an outlet configured to output the cells, a plurality of main channels, and one or more bypass channels. The main channels are disposed between the inlet and the outlet and are provided with microconstrictions that are parallelized such that images of the cells are captured within a single field of view (FOV) when the cells pass through the microconstrictions and are deformed therein. The one or more bypass channels are independent from the main channels, thereby stabilizing pressure drop between the inlet and the outlet.
Electrochemical conversion of nitrate to ammonia is an approach to alleviate nitrate pollution in water and simultaneously generate green NH3 fuels. The practical application of this approach is challenging due to the lack of efficient electrocatalysts. The present disclosure relates generally to an electrocatalyst including a plurality of CuWO4 hollow nanospheres, which include asymmetric oxygen vacancies and adjacent Mo clusters, and methods of making and using the same. The electrocatalyst of the present disclosure is designed for efficient ammonia electrosynthesis.
C25B 11/091 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques
C25B 11/02 - ÉlectrodesLeur fabrication non prévue ailleurs caractérisées par la configuration ou la forme
C25B 11/052 - Électrodes comportant un substrat et un ou plusieurs revêtements électro-catalytiques
54.
MEANS FOR PREPARING A POLYMER FILM, AND A POLYMER FILM PREPARED THEREOF
The present invention relates to a method for preparing a polymer film, comprising the following steps: preparing a polymer film with a polymer solution prepared from PVDF and/or TPU; preparing a mixed solvent selected from a group consisting of dimethylformamide, dimethylacetamide, ethanol, water, or any combination thereof, wherein said mixed solvent is characterized by the solubility of said mixed solvent to the polymer selected for said polymer solution and/or the contact angle of said mixed solvent on said polymer film; wetting said polymer film with said mixed solvent; and subjecting the wet polymer film to thermal treatment under pressure.
Provided is a method for preparing a polymer film, comprising the following steps: preparing a polymer film with a polymer solution prepared from PVDF and/or TPU; preparing a mixed solvent selected from a group consisting of dimethylformamide, dimethylacetamide, ethanol, water, or any combination thereof, wherein said mixed solvent is characterized by the solubility of said mixed solvent to the polymer selected for said polymer solution and/or the contact angle of said mixed solvent on said polymer film; wetting said polymer film with said mixed solvent; and subjecting the wet polymer film to thermal treatment under pressure.
D04H 1/00 - Non-tissés formés uniquement ou principalement de fibres coupées ou autres fibres similaires relativement courtes
D04H 1/728 - Non-tissés formés uniquement ou principalement de fibres coupées ou autres fibres similaires relativement courtes caractérisés par la méthode de formation des voiles ou couches, p. ex. par la réorientation des fibres les fibres étant disposées au hasard par électrofilage
D04H 1/54 - Non-tissés formés uniquement ou principalement de fibres coupées ou autres fibres similaires relativement courtes à partir de voiles ou couches composés de fibres ne possédant pas des propriétés cohésives réelles ou potentielles par soudage des fibres ensembles, p. ex. par fusion partielle ou dissolution
D04H 1/541 - Fibres composites, p. ex. âme-gaine, mer-île ou côte à côteFibres mixtes
56.
Microfluidic-based Device For In Vivo Wound Infection Model And Uses Thereof
The present invention provides an integrated microfluidic-based device for establishing a wound infection in vivo model suitable for high throughput bioassay such as potential drug screening, in vivo dosing optimization, host-microbe or microbe-microbe interactions under the influence of specific agents of interest, and studying regulatory mechanisms of certain inflammatory diseases relating to or arising from the wound infection. The present invention allows direct qualitative and quantitative assessments of specific markers expressed due to the wound infection by one or more microbes devoid of cell sorting, isolation, or labelling as in other conventional in vivo models or methods.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
57.
SINGLE VESSEL MULTI-ZONE BIOREACTOR FOR SIMULTANEOUS CULTURE OF MULTIPLE MICROBIAL STRAINS
ROYAL MELBOURNE INSTITUTE OF TECHNOLOGY (Australie)
CITY UNIVERSITY OF HONG KONG (Chine)
Inventeur(s)
Mettu, Srinivas
Roy Choudhury, Namita
Dutta, Naba Kumar
Lin, Carol Sze Ki
Hathi, Zubeen
Abrégé
A single vessel multi-zone bioreactor for simultaneously culturing multiple microbial strains comprising multiple culturing zones arranged sequentially, each culturing zone comprising a porous hydrogel, and the use thereof for producing optionally encapsulated probiotics.
A framework that comprises a reinforcement-learning-based neural-network for compressing, and for transmitting the compressed genomes over a data network in repeated steps each of a plurality of species. The framework also takes data on inefficient transmission of compressed genome in the preceding step, and feeds this data forward to modify the selection of the compression parameter in the present step. The invention provides the possibility that the genome of any species may be compressed optimally and transmitted in optimal efficiency. That is, big genome sequence is neither over compressed, which takes a lot of processing time leading to delays, nor under compressed which will require more time to transmit.
A microfluidic device for visual quantification and determining of one or more material particles in a solution of material particles. The microfluidic device comprises: an inlet for receiving a solution, and a trap which is in fluid communication with the inlet and traps one or more material particles in the solution of material particles. The solution of material particles may be a sample solution received at the inlet or a treated solution obtained by post-treating the sample solution received at the inlet. The trap comprises a fluid channel, so that the presence and/or amount of one or more trapped material particles are determined in a visual form. The present invention further describes a method for using the device.
The present invention provides an integrated sweat sensing system including a multi-layered structure incorporating a flexible circuitry sensing layer with multiple electronic and mechanical components responsible for sensing certain physiological changes of a user and giving feedback signals to the user when a detectable biological, chemical or physiological signal exceeds certain threshold. The system further includes a microfluidic based biosensing platform responsible for sensing changes in sweat component composition including ions, glucose and pH changes, and subsequently trigger feedback signal outputs from the flexible circuitry sensing layer to provide the user with a corresponding change-of-state signal. The present system is bendable and detachably mountable on various skin regions of the user.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 5/1477 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques non invasifs
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
61.
Acoustic-based face anti-spoofing system and method
Two-dimensional face presentation attacks are one of most notorious and pervasive face spoofing types, causing security issues to facial authentication systems. To tackle these issues, a cost-effective face anti-spoofing (FAS) system based on acoustic modality, named as Echo-FAS, is devised, which employs a crafted acoustic signal to probe the presented face. First, a large-scale, high-diversity, acoustic-based FAS database, named as Echo-Spoof, is built. Based upon Echo-Spoof, we design a two-branch framework combining global and local frequency features of the presented face to distinguish live vs. spoofing faces. Echo-FAS has the following merits: (1) it only needs one speaker and one microphone; (2) it can capture three-dimensional geometrical information of the presented face and achieve a remarkable FAS performance; and (3) it can be handily allied with RGB-based FAS models to mitigate the overfitting problem in the RGB modality and make the FAS model more accurate and robust.
G06F 18/2131 - Extraction de caractéristiques, p. ex. en transformant l'espace des caractéristiquesSynthétisationsMappages, p. ex. procédés de sous-espace basée sur un traitement dans le domaine de transformation, p. ex. transformée en ondelettes
62.
BIOSENSING SYSTEM AND METHOD FOR IN-SITU DETERMINATION OF METASTASIS IN A SAMPLE
The present invention provides a biosensing system including a microfluidic-based biosensor designed for both point-of-care testing and a home-based assessment. A method for distinguishing a metastatic sample from a non-metastatic sample in-situ based on an observation of relative distribution of organisms in a biosensor of the present system in response to different test samples through a portable imaging device or an imaging module integrated into a smartphone or mobile device is also provided. Chemotactic preference of the organisms to a sample is quantified by using Raman spectroscopy to generate a profile of target analytes for determination of metastatic status and potential in a particular sample.
One embodiment includes an electromagnetic device for generating a magnetic field in a workspace. The electromagnetic device includes an elongated sleeve defining a hollow space and having an external surface, a magnetic core, and an electric coil wounded onto the external surface of the elongated sleeve and configured to generate the magnetic field when energized. The magnetic core has a first end, a second end, and a middle portion that is disposed between the first end and the second end and received in the hollow space. The first end is provided with a core tip that is shaped substantially as a cone and has a cone radius greater than zero.
H01H 47/00 - Circuits autres que ceux appropriés à une application particulière du relais et prévue pour obtenir une caractéristique de fonctionnement donnée ou pour assurer un courant d'excitation donné
The present invention relates to methods modifying cell surface markers of red blood cells (RBCs) and uses of the same. In particular, the method comprises contacting an RBC with a peptide in the presence of a ligase, under suitable conditions and for sufficient time to allow ligation of the peptide to the RBC to form an RBC-peptide conjugate. In one embodiment, the ligase is OaAEPI ligase. The RBC-peptide conjugate may be further contacted with an effector molecule under suitable conditions and for sufficient time for conjugation of the effector molecule to the RBC-peptide to form an RBC-peptide-effector molecule conjugate.
The present invention provides a platform for large-scale profiling of post-transcriptional molecular targets including microRNAs (miRNAs) and methylated messenger RNAs (such as m6A mRNAs) with subcellular spatial resolution in a tissue-wide scale. The present platform is capable of high-throughput isolation of intracellular molecules by contacting an array of functionalized nanoprobes with a target tissue sample for capturing the molecular targets, and the isolated molecular targets are in-situ analysed. The present invention also provides a spectrum barcoding system and related method for digitally quantifying the isolated molecular targets on the nanoprobes and mapping with an imprint of the tissue sample to provide a single-cell spatial coordinate and expression pattern of each of the molecular targets corresponding to different sub-regions of the tissue sample.
An integrated device for rapid detection of SARS-CoV-2 is disclosed. The integrated device includes a front-end system, a back-end system, and a microfluidic channel. The front-end system includes a detection region and a control region. The detection region and the control region have similar structures, each including an interdigital electrode and a graphene film. The microfluidic channel is arranged to cover the detection region so as to allow the interdigital electrode of the detection region to be exposed to the breath sample. The graphene film of the detection region has a surface resistance higher than that of the graphene film of the control region when the detection region is exposed to a selected virus. The back-end system is configured to detect and compare the surface resistance of the graphene films of the detection region and the control region for determining whether the selected virus is present in the breath sample.
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
G01K 7/22 - Mesure de la température basée sur l'utilisation d'éléments électriques ou magnétiques directement sensibles à la chaleur utilisant des éléments résistifs l'élément étant une résistance non linéaire, p. ex. une thermistance
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
67.
HYDRODYANMIC CELL PAIRING AND FUSION SYSTEM AND RELATED METHODS
The present invention provides a non-mediative approach to capture biological cells and initiate cell pairing and fusion in a microfluidic-based system with multiple channels configured in various dimensions and shapes in order to create a hydrodynamic platform incorporating a passive trapping mechanism to entrap the cells of interest from fluid flowing through the multiple channels and allow cell fusion with certain rheological deformation in the absence of any cell disruption while the whole cell pairing and fusion process is closely monitored by simple optical monitoring device.
C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12N 15/02 - Préparation de cellules hybrides par fusion de plusieurs cellules, p. ex. fusion de protoplastes
A molecular point-of-care testing (POCT) diagnostic device for molecular detection of various diseases with “sample-in-result-out” principle is provided. The device has a sample tube in which a test sample is mixed with a sample buffer, a microfluidic-based reaction tube with a simple flow-based system for amplifying the sample buffer mixed with the test sample to form an amplified result, and a closed-system, disposable result interpretation using colorimetric- or lateral flow assay-based for assaying the amplified result. The device is portable and simple to use, which can help bring laboratory detection to the field.
An eco-tile useful for promoting the growth of fauna and flora in an aquatic environment, the eco-tile including at least one type of cement; aggregates comprising at least two fine aggregates and coarse aggregates; and milled incineration sewage sludge ashes, wherein the at least two fine aggregates comprise dredged marine sediment, eco-concrete precursors thereof, and methods of use and preparation of the same.
C04B 20/00 - Emploi de matières comme charges pour mortiers, béton ou pierre artificielle prévu dans plus d'un groupe et caractérisées par la forme ou la répartition des grainsTraitement de matières spécialement adapté pour renforcer leur propriétés de charge dans les mortiers, béton ou pierre artificielle prévu dans plus d'un groupe de Matières expansées ou défibrillées
C04B 28/28 - Compositions pour mortiers, béton ou pierre artificielle, contenant des liants inorganiques ou contenant le produit de réaction d'un liant inorganique et d'un liant organique, p. ex. contenant des ciments de polycarboxylates contenant des polyacides organiques, p. ex. contenant des ciments de polycarboxylates
C04B 24/26 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
70.
RADIATIVE COOLING MATERIAL AND STRUCTURE FOR FACILITATING COOLING OF WEARABLE ELECTRONIC DEVICE
A radiative cooling material for facilitating cooling of a wearable electronic device. The radiative cooling material includes a polymeric matrix and one or more materials dispersed in the polymeric matrix. The radiative cooling material is operable to facilitate reflection of solar radiation in at least some solar spectrum wavelengths, when the radiative cooling material is exposed to solar radiation. The radiative cooling material is also operable to facilitate emission of thermal radiation in at least some infrared spectrum wavelengths.
The present invention provides an implantable electrostimulation-based drug delivery system incorporating microneedle-based drug delivery module connecting with a wirelessly-controlled electrostimulation module such that under a small input power generated by magnetic coupling between a transmission antenna and a harvester of the wirelessly-controlled electrostimulation module, one or more substances stored in the microneedles can be released to tissues of a target site while no subsequent removal of the system from the target site is required as the system is entirely biodegradable and bioresorbable in vivo after a sufficient period of time.
A61M 37/00 - Autres appareils pour introduire des agents dans le corpsPercutanisation, c.-à-d. introduction de médicaments dans le corps par diffusion à travers la peau
72.
SINGLE-ATOMICALLY DISPERSED METAL / UNCONVENTIONAL-PHASE TRANSITION-METAL DICHALCOGENIDE NANOSHEET HYBRIDS AND METHODS OF PREPARATION AND USE THEREOF
A single-atomically dispersed metal/two-dimensional transition-metal dichalcogenide nanosheet hybrid comprising a plurality of single-atomically dispersed metal atoms disposed on at least one surface of a transition-metal dichalcogenide nanosheet, wherein the transition-metal dichalcogenide nanosheet is uniformly crystalline.
C25B 11/093 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques au moins un métal noble ou oxyde de métal noble et au moins un oxyde d’un métal non noble
C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
73.
METHOD OF FLOCULATION USING A METAL-ORGANIC-FRAMEWORK
The present disclosure relates to a method of flocculation, wherein harmful cyanobacteria are flocculated via metal-organic framework, and wherein the metal-organic framework comprises chromium, which is environmentally friendly. Water-stable Cr(III)-based MOFs, structured as NH2-MIL-101, remove harmful algal blooms, such as Microcystis aeruginosa, from natural water sources by promoting flocculation. NH2-MIL-101(Cr) MOFs efficiently remove harmful algae from water without creating secondary pollution and without causing the harmful algae to release intracellular toxins.
A61K 31/7072 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées ayant des groupes oxo liés directement au cycle pyrimidine, p. ex. cytidine, acide cytidylique ayant deux groupes oxo liés directement au cycle pyrimidine, p. ex. uridine, acide uridylique, thymidine, zidovudine
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
Provided are a hydrogel-based cell encapsulation method, a cell-encapsulating polymerized microgel prepared therefrom, and a kit thereof. The hydrogel-based cell encapsulation method can include: (a) providing a cell suspension as an aqueous phase comprising cells, alginate and a culture medium; (b) preparing an emulsion using the cell suspension and an oil phase through a droplet microfluidic device such that one or more of the cells are each encapsulated in at least a portion of the droplets thereby forming an emulsion comprising cell-encapsulating droplets and empty droplets; (c) incubating the emulsion, and then cross-linking alginate in the cell-encapsulating droplets in the presence of a cross-linker to form cell-encapsulating polymerized microgels; and (d) optionally, demulsifying, separating and collecting the cell-encapsulating polymerized microgels.
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
C12N 11/04 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique piégées à l’intérieur du support, p. ex. dans un gel ou dans des fibres creuses
76.
MICRO-ELECTROPORATION BASED DRUG DELIVERY SYSTEM, METHODS FOR USE AND FABRICATION THEREOF
The present invention provides an electricity-driven, micro-electroporation based drug delivery system, in particular, an electrically conductive array of microprotrusions containing intended substances or molecules to be delivered, which is to the benefit of a recipient receiving vaccination transcutaneously in the absence of any assistive mechanical or actuation means as in conventional injection methods, so as to lower safety risks, improve immunization efficiency, and also induce immune response of the recipient more effectively at a relatively lower dose of vaccines.
A61M 37/00 - Autres appareils pour introduire des agents dans le corpsPercutanisation, c.-à-d. introduction de médicaments dans le corps par diffusion à travers la peau
A61N 1/32 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents
B29C 39/02 - Moulage par coulée, c.-à-d. en introduisant la matière à mouler dans un moule ou entre des surfaces enveloppantes sans pression significative de moulageAppareils à cet effet pour la fabrication d'objets de longueur définie, c.-à-d. d'objets séparés
B29C 39/00 - Moulage par coulée, c.-à-d. en introduisant la matière à mouler dans un moule ou entre des surfaces enveloppantes sans pression significative de moulageAppareils à cet effet
77.
CONFINED MIGRATION MICROFLUIDIC DEVICE FOR CELL CULTURE AND DRUG SCREENING
Provided is a confined migration microfluidic device for cell culture and drug screening, including a chip including a plurality of parallel channels, where each pair of it is connected through a plurality of the confined migration channels; a depth of the confined migration channel is lower than the first channel and second channel; a first/second inlet and a first/second outlet are provided at two ends of the first/second channel, respectively; and a pyramid-like structure for diverging flow to the first channels to ensure evenly distribution. During the usage, cells to be cultured are added into one of the first channel and the second channel, and drugs or cells which can influence confined migration of the target cells are added into the other channel; the inhibitory effect of the drugs or cells on the confined migration will be evaluated, thereby screening/studying effective drugs and cells in relation to the confined migration.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
78.
Label-free liquid biopsy-based disease model, analytical platform and method for predicting disease prognosis
The present disclosure provides a platform and method for predicting disease prognosis based on label-free liquid biopsy, in particular, to establish a disease model in vitro on a microfluidic device and provide a trained deep learning neural network for automatically extracting morphological features from cell clusters formed by the label-free liquid biopsy of a test subject in order to predict different disease stages and evaluate efficacies of a corresponding treatment regime to the test subject. The present disclosure also provides a method for training the neural network based on different cell cluster datasets obtained from the disease model corresponding to different deep learning models of the neural network.
A nano scale robotic system for single cell DNA sequencing of a strand of DNA positioned on a slide utilizes an atomic force microscope (AFM) having an end effector in the form of a cantilever with a tip. The AFM causes its cantilever tip to scan over the base pairs of the DNA strand. A pair of spaced-apart electrodes at the tip makes contact with opposite sides of the DNA strand and the current between bases of the DNA strand is measured by a current measurement system connected to the electrodes. An artificial intelligence-based data analytic system determines the DNA sequence based on the current from the current measuring system. The AFM tip is guided over the DNA strand by comparing compressed desired intensity local scan images and compressed actual intensity local scan images and using the difference to control the location of the tip.
G01Q 30/02 - Dispositifs d'analyse d’un type autre que la microscopie à sonde à balayage SPM, p. ex. microscope électronique à balayage SEM [Scanning Electron Microscope], spectromètre ou microscope optique
G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet
The present invention provides piezoelectric bio-organic films resembling ceramic-based piezoelectric films, and also a fabrication method thereof. In particular, the bio-organic piezoelectric films are formed by compact nanocrystals resembling the inorganic ceramic structure, where nanocrystallization on biomaterials and in-situ electric field are applied to facilitate domain orientation alignment across the entire films. The present fabrication method provides flexibility to tune various parameters of the resulting bio-organic films according to the needs, and therefore is substantially applicable to a wide range of biomaterials to form piezoelectric bio-organic films comparable to those formed by conventional piezoceramics in terms of piezoelectricity, thermostability and durability.
B29C 41/00 - Façonnage par revêtement d'un moule, noyau ou autre support, c.-à-d. par dépôt de la matière à mouler et démoulage de l'objet forméAppareils à cet effet
An electrotactile apparatus has an electrode-array unit and a driver unit for generating a haptic feedback to a user. The electrode-array unit uses electrodes to electro-stimulate the user's skin with pulsed voltage signals generated by the driver unit, inducing excitation currents flowing in the user to generate the haptic feedback. The driver unit is self-powered or wirelessly powered for supporting untethered electrotactile stimulation to the user. A common counter electrode installed on the driver unit contacts the user's skin and collects the excitation currents returned from the user. Advantageously, the common counter electrode is located on an outer surface of the driver unit and the driver unit is substantially flexible, facilitating the common counter electrode to seamlessly contact the user's skin for achieving a stable electrode-skin interface while positioning the driver unit as a whole on the user's skin to provide untethered virtual touching experience to the user.
H04W 4/80 - Services utilisant la communication de courte portée, p. ex. la communication en champ proche, l'identification par radiofréquence ou la communication à faible consommation d’énergie
G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
G06F 3/041 - Numériseurs, p. ex. pour des écrans ou des pavés tactiles, caractérisés par les moyens de transduction
IMPERIAL COLLEGE INNOVATIONS LIMITED (Royaume‑Uni)
CITY UNIVERSITY OF HONG KONG (Chine)
Inventeur(s)
Long, Nicholas
Sheppard, Stephanie
Zhu, Zonglong
Li, Zhen
Abrégé
A photovoltaic cell comprising a perovskite layer (110), an electron transporting layer (106) and an interface layer (108) disposed between the electron transporting layer and the perovskite layer. The interface layer comprises a metallocene substituted with a substituent having an O, S, N or P group, for example ferrocene substituted with a thienyl-carboxylate group.
H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
H10K 30/85 - Couches à haute mobilité électronique, p. ex. couches de transport d'électrons ou couches de blocage de trous
The invention provides an enhanced electrospun film made from polyvinylidene fluoride (PVDF) and at least one low-melting-point polymer in a ratio of 99.9:0.1-90:10 by weight, and the low-melting-point polymer having a melting point lower than the polyvinylidene fluoride and a softening point in the range of 110-140 C°. The enhanced electrospun film exhibits excellent mechanical properties, higher moisture permeability and hydrostatic pressure resistance. The invention further provides a method for manufacturing the enhanced PVDF electrospun film, and use of the enhanced PVDF electrospun film in preparing a waterproof and moisture permeable product.
D01D 5/00 - Formation des filaments, fils ou similaires
D01F 6/50 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de mélanges de polymères obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone comme constituant majeur avec d'autres polymères ou des composés de bas poids moléculaire de polyalcools, polyacétals ou polycétals
D01F 6/48 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de mélanges de polymères obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone comme constituant majeur avec d'autres polymères ou des composés de bas poids moléculaire de polymères d'hydrocarbures halogénés
D04H 1/728 - Non-tissés formés uniquement ou principalement de fibres coupées ou autres fibres similaires relativement courtes caractérisés par la méthode de formation des voiles ou couches, p. ex. par la réorientation des fibres les fibres étant disposées au hasard par électrofilage
Korea University Research and Business Foundation (République de Corée)
City University of Hong Kong (Chine)
Inventeur(s)
Jang, Woo Young
Hwang, Jangsun
Xu, Chenjie
Abrégé
The present disclosure relates to a nanosensor for real-time monitoring of wound healing, a manufacturing method thereof, and a real-time monitoring system for wound healing using the same. A nanosensor according to example embodiments includes a biomarker for detecting mRNA and a reference gene on gold nanoparticles, thereby providing an objective indicator through monitoring of wound healing, enabling monitoring of wound healing through direct monitoring using real-time fluorescence by including a fluorescent marker in a nanoflare, and enabling evaluation of a whole wound healing process in normal and patient groups (diabetes) through real-time monitoring. In addition, the nanosensor according to the example embodiments has advantages of shortening synthesis time and improving efficiency by 30% through integration of a novel synthesis method (freezing method) rather than an existing synthesis method (salt aging).
A method of managing real-time electrical energy storage management from an electricity storage device to maximise the reduction of the use of a mains electricity grid during peak cost charging periods on the mains electricity grid, including: calculating an ideal offline use of the electricity storage device using ideal predicted parameters; calculate a plurality of electrical storage device storage and electrical discharge models using a plurality of algorithms based on recorded data; calculate the competitive ratio for each of the algorithms and the ideal offline use; and use power from the electricity storage device based on an optimal competitive ratio.
H02J 3/14 - Circuits pour réseaux principaux ou de distribution, à courant alternatif pour règler la tension dans des réseaux à courant alternatif par changement d'une caractéristique de la charge du réseau par interruption, ou mise en circuit, des charges du réseau, p. ex. charge équilibrée progressivement
86.
ELECTROSPUN FILM, AND MANUFACTURING METHOD THEREFOR AND USE THEREOF
An enhanced PVDF electrospun film, which is prepared from polyvinylidene fluoride and at least one low-melting-point polymer having a melting point lower than that of polyvinylidene fluoride at a weight ratio of 99.9:0.1 to 90:10, wherein the softening point of the low-melting-point polymer is in the range of 110-140ºC. The enhanced electrospun film has good mechanical properties, a higher water vapor transmission rate, and hydrostatic pressure resistance. Further provided are a manufacturing method for the enhanced PVDF electrospun film and the use of the enhanced PVDF electrospun film in the preparation of a waterproof and moisture-permeable product.
D04H 1/728 - Non-tissés formés uniquement ou principalement de fibres coupées ou autres fibres similaires relativement courtes caractérisés par la méthode de formation des voiles ou couches, p. ex. par la réorientation des fibres les fibres étant disposées au hasard par électrofilage
D01F 8/06 - Filaments, ou similaires, faits par l’homme, conjugués, c.-à-d. à plusieurs composantsLeur fabrication à partir de polymères synthétiques avec au moins une polyoléfine comme constituant
D01F 8/16 - Filaments, ou similaires, faits par l’homme, conjugués, c.-à-d. à plusieurs composantsLeur fabrication à partir de polymères synthétiques avec au moins un autre composé macromoléculaire obtenu par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone comme constituant
87.
FLEXIBLE SMELL GENERATING DEVICE AND METHODS FOR USE THEREOF
The present invention provides a thermo-controlled smell generating device with an active cooling mechanism to allow a user thereof to control on/off of the device in a relatively short response time absent any temperature fluctuations even after a significant number of heating and cooling cycles. The present invention is ideal for generating olfaction in highly interactive or fast-changing environments such as virtual immersive environments.
A61M 21/02 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscienceDispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p. ex. pour mettre en état d'hypnose pour provoquer le sommeil ou la relaxation, p. ex. par stimulation directe des nerfs, par hypnose ou par analgésie
G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
88.
Flexible patterned piezoceramic composite and manufacturing method thereof
The present invention provides a surface tension assisted film forming method to prepare a flexible, patterned piezoceramic composite for use in a variety of electronics. The present method allows tuning mechanical and piezoelectric properties of the resulting composite by simply adjusting one or few parameters used during the piezoceramic film forming and/or composite forming procedures in the absence of any complex transferring techniques that are commonly used in conventional methods. The present invention also allows customizing patterns (two-dimensional or three-dimensional) on the piezoceramic framework to result in a piezoelectric composite that is able to provide anisotropic piezoelectric responses to different loads whilst still having a constant electrical output over a long-time deformation.
H10N 30/045 - Traitements afin de modifier une propriété piézo-électrique ou électrostrictive, p. ex. les caractéristiques de polarisation, de vibration ou par réglage du mode par polarisation
H10N 30/06 - Formation d’électrodes ou d’interconnexions, p. ex. de connections électriques ou de bornes
H10N 30/078 - Formation de parties ou de corps piézo-électriques ou électrostrictifs sur un élément électrique ou sur un autre support par dépôt de couches piézo-électriques ou électrostrictives, p. ex. par impression par aérosol ou par sérigraphie par dépôt en phase liquide par dépôt sol-gel
H10N 30/85 - Matériaux actifs piézo-électriques ou électrostrictifs
H10N 30/87 - Électrodes ou interconnexions, p. ex. connexions électriques ou bornes
89.
METHODS AND SYSTEMS FOR MEASURING MULTIPLEX RNA EXPRESSION
A method of measuring RNA expression level of a target sequence in a sample is performed by simultaneously enriching the target sequence and corresponding RNA and calculating a RNA-to-DNA ratio of the same target sequence. A method of treating cancer includes the step of using the method of measuring RNA expression level of a target sequence. A kit includes components for performing the method of measuring RNA expression level of a target sequence.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
90.
Power generating and gait assisting footwear article
The present invention provides a device for improving energy economy and wearing comfort of a power generating, gait assisting footwear article while maintaining normal gait pattern during human locomotion. The device includes a motion conversion mechanism to convert linear reciprocating moment exerted on the device during heel strike/up into a series of rotations; a rotation acceleration module to increase the speed of rotations before being transformed into electric current by a generator. The device also includes a power management module and energy storage element(s) for energy storage and power supply to the footwear article or external electronics.
A43B 7/32 - Chaussures avec dispositions médicales ou hygiéniques avec dispositifs amortisseurs de chocs
H02N 2/18 - Machines électriques en général utilisant l'effet piézo-électrique, l'électrostriction ou la magnétostriction fournissant une sortie électrique à partir d'une entrée mécanique, p. ex. générateurs
Disclosed herein are methods of detecting the presence or absence of exosomes, the method comprising detecting an exosomal biomarker in a sample obtained from a subject. Also disclosed herein is a system and a biosensor, each for detecting an exosomal biomarker as disclosed herein.
G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
93.
Computerized method of composing a system for performing a Task
Disclosed is a computer-implemented method of composing, using natural language processing, a system for performing a task. The method comprises receiving a user input comprising a sequence of words; processing the user input using a neural network for entity recognition to identify, from the sequence of words, a term defining an event; and searching a data store having stored therein data indicative of a plurality of components, using the identified term, to determine a component for the system.
G06F 30/12 - CAO géométrique caractérisée par des moyens d’entrée spécialement adaptés à la CAO, p. ex. interfaces utilisateur graphiques [UIG] spécialement adaptées à la CAO
G06F 40/40 - Traitement ou traduction du langage naturel
A method for extracting latent vector autoregressive (LaVAR) models with full interactions amongst mutually independent dynamic latent variables (DLV) from multi-dimensional time series data comprising: detecting, by a plurality of sensors, dynamic samples of data corresponding to a plurality of original variables; analyzing, using a controller, the dynamic samples of data to determine a plurality of latent variables that represent variation in the dynamic samples of data; estimating an estimated current value for all of the latent variables, wherein the estimation for all of the latent values is conducted simultaneously through an iterative process; and wherein each of the latent variables are contemporaneously uncorrelated.
A method, system, apparatus and a non-transitory computer-readable medium storing instruction thereon is provided for predicting a probability of a synergistic effect between a combination of drugs in the treatment of, for example, a complex disease, such as cancer, through the application of an end-to-end deep learning framework based on a protein-protein interaction (PPI) network, drug-protein associations and cell line-protein associations.
G16H 70/40 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des médicaments, p. ex. leurs effets secondaires ou leur usage prévu
One embodiment provides a method for controlling a microagent in a workspace. The method includes providing a plurality of magnetic sources and generating a rotating gradient magnetic field by activating the plurality of magnetic sources differently such that a driving force is created to drive the microagent towards an aggregation center in the workspace.
H01H 47/00 - Circuits autres que ceux appropriés à une application particulière du relais et prévue pour obtenir une caractéristique de fonctionnement donnée ou pour assurer un courant d'excitation donné
H01F 7/06 - Électro-aimantsActionneurs comportant des électro-aimants
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
B32B 5/02 - Produits stratifiés caractérisés par l'hétérogénéité ou la structure physique d'une des couches caractérisés par les caractéristiques de structure d'une couche comprenant des fibres ou des filaments
B32B 5/24 - Produits stratifiés caractérisés par l'hétérogénéité ou la structure physique d'une des couches caractérisés par la présence de plusieurs couches qui comportent des fibres, filaments, grains ou poudre, ou qui sont sous forme de mousse ou essentiellement poreuses une des couches étant fibreuse ou filamenteuse
B32B 15/14 - Produits stratifiés composés essentiellement de métal adjacent à une couche fibreuse ou filamenteuse
D06M 11/13 - Halogénures d'ammonium ou halogénures d'éléments des groupes 1 ou 11 du tableau périodique
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
CENTRE FOR REGENERATIVE MEDICINE AND HEALTH, HONG KONG INSTITUTE OF SCIENCE & INNOVATION, CHINESE ACADEMY OF SCIENCES LIMITED (Chine)
CITY UNIVERSITY OF HONG KONG (Chine)
Inventeur(s)
Tortorella, Mickey Daniel
He, Jufang
Abrégé
A polypeptide and an application thereof as a CCK receptor agonist/antagonist. The polypeptide has relatively high agonistic activity/antagonistic activity on a CCK receptor. Compared with a polypeptide CCK4, the polypeptide has a longer half-life period and curative effect duration in vivo. Experiments prove that the polypeptide has an obvious improvement effect on spatial memory deficits of old mice, old memory deficient mice, and Alzheimer's disease mice, such that the polypeptide has great application potential.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
An underwater vehicle for performing a variety of linear motions and turning motions with better stability and agility is disclosed. The underwater vehicle includes a main body, a front-drive mechanism, a rear-drive mechanism, and a steering assembly. The main body has a front end and a rear end, which defines a longitudinal axis extending from the front end to the rear end of the main body. The front-drive mechanism is connected to the main body to provide a forward propelling force in a direction parallel to the longitudinal axis. The steering assembly is fixed to the rear end and coupled to the rear-drive mechanism. The steering assembly is configured to rotate the rear-drive mechanism with respect to the longitudinal axis by a body angle for providing a lateral force on the main body.
DeepOPF-V, a deep neural network (DNN)-based voltage-constrained approach for solving an alternating-current optimal power flow (AC-OPF) problem, is used to determine an operating point of an AC electrical power system. DeepOPE-V advantageously uses two DNNs to separately determine voltage magnitudes and voltage phase angles of buses in the system without cross-over operations between the two DNNs. A computation complexity is reduced when compared to using a single DNN for generating both the magnitudes and phase angles, allowing high computation efficiency achieved by DeepOPE-V. Remaining variables of the system are computed based on the determined magnitudes and phase angles. A solution for the operating condition is predicted. A fast post-processing (PP) method is developed to improve the feasibility of the predicted solution. The PP method uses linear adjustment to adjust the predicted solution to improve the solution feasibility while enabling fast execution of the PP method.
H02J 13/00 - Circuits pour pourvoir à l'indication à distance des conditions d'un réseau, p. ex. un enregistrement instantané des conditions d'ouverture ou de fermeture de chaque sectionneur du réseauCircuits pour pourvoir à la commande à distance des moyens de commutation dans un réseau de distribution d'énergie, p. ex. mise en ou hors circuit de consommateurs de courant par l'utilisation de signaux d'impulsion codés transmis par le réseau
G01R 19/00 - Dispositions pour procéder aux mesures de courant ou de tension ou pour en indiquer l'existence ou le signe
G01R 25/00 - Dispositions pour procéder aux mesures de l'angle de phase entre une tension et un courant ou entre des tensions ou des courants
H02J 3/16 - Circuits pour réseaux principaux ou de distribution, à courant alternatif pour règler la tension dans des réseaux à courant alternatif par changement d'une caractéristique de la charge du réseau par réglage de puissance réactive