The present invention is comprised in the cosmetic and/or therapeutic industry and specifically relates to a new composition for topical use with antioxidant and hydrating activity which promotes wound healing and is useful in therapeutic and/or cosmetic treatment, as well as in the prevention of skin lesions.
The present invention is comprised in the cosmetic and/or therapeutic industry and specifically relates to a new composition for topical use with antioxidant and hydrating activity which promotes wound healing and is useful in therapeutic and/or cosmetic treatment, as well as in the prevention of skin lesions.
The novel composition object of the present invention incorporates certain agents and ingredients, among which are carotenoids and the galactomannans, which surprisingly improve the healing and curing activity in a broad spectrum of wounds occurring with the presence of reactive oxygen species.
A61K 31/736 - Glucomannanes ou galactomannanes, p. ex. gomme de caroube, gomme de guar
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
The present invention is intended for use in the cosmetic and/or therapeutic industry and specifically relates to a new composition for topical use with antioxidant and hydrating activity which promotes wound healing and is suitable for use in the therapeutic and/or cosmetic treatment, and also prevention, of skin lesions. The novel composition of the present invention incorporates certain agents and ingredients, including carotenoids and galactomannans, which dramatically improve the healing and curing activity across a broad spectrum of wounds associated with the presence of reactive oxygen species.
A61L 26/00 - Aspects chimiques des bandages liquides ou utilisation de matériaux pour les bandages liquides
A23L 5/44 - Adjonction de colorants ou de pigments, p. ex. en combinaison avec des azurants optiques en utilisant des colorants ou des pigments organiques d'origine naturelle, leurs doublons artificiels ou leurs dérivés en utilisant des caroténoïdes ou des xanthophylles
The present invention is comprised in the cosmetic and/or therapeutic industry and specifically relates to a new composition for topical use with antioxidant and hydrating activity which promotes wound healing and is useful in therapeutic and/or cosmetic treatment, as well as in the prevention of skin lesions. The novel composition object of the present invention incorporates certain agents and ingredients, among which are carotenoids and the galactomannans, which surprisingly improve the healing and curing activity in a broad spectrum of wounds occurring with the presence of reactive oxygen species.
A23L 5/44 - Adjonction de colorants ou de pigments, p. ex. en combinaison avec des azurants optiques en utilisant des colorants ou des pigments organiques d'origine naturelle, leurs doublons artificiels ou leurs dérivés en utilisant des caroténoïdes ou des xanthophylles
05 - Produits pharmaceutiques, vétérinaires et hygièniques
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical preparations for medical and veterinary use; Sanitary preparations for medical purposes; Chemico-pharmaceutical preparations; Skin care preparations for medical use; Pharmaceutical preparations for skin care; Antimicrobials for dermatologic use; Stem cells for medical purposes; Stem cells for veterinary purposes; Cultures for medical use; Cultures for veterinary use; Cellular function activating agents for medical purposes; Surgical implants grown from stem cells; Transplants [living tissues]; Bandages for skin wounds; Pharmaceutical agents for treating physically caused lesions; Surgical plasters; Materials for dressings; Homeopathic pharmaceuticals; Dietetic food and substances adapted for medical or veterinary use, food for babies; Food supplements for human beings and animals; Mineral food supplements; Material for stopping teeth, dental wax; Teeth filling material; Dietary supplements with a cosmetic effect; Disinfectants; Preparations for destroying vermin; Herbicides; Fungicides. Medical services; Medical services; Medical services in the field of treatment of chronic pain; Advisory services relating to degenerative diseases; Providing medical advice in the field of dermatology; Dermatological services for treating skin conditions; Consultancy services relating to cosmetics; Psychological counseling; Psychiatric services; Performing diagnosis of diseases; Medical testing services relating to the diagnosis and treatment of disease; Alternative medicine services; Stem cell storage; Medical services relating to the removal, treatment and processing of stem cells; Medical services relating to the removal, treatment and processing of bone marrow; Analysis of human tissues for medical treatment; Cosmetic treatment; Veterinary services; Human hygiene and beauty care; Hygienic and beauty care for animals; Development of individual physical rehabilitation programmes; Advice relating to the personal welfare of elderly people [health]; Agriculture, horticulture and forestry services; Providing information about agriculture, horticulture, and forestry services; Medical equipment rental.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical preparations for medical and veterinary use; Sanitary preparations for medical purposes; Pharmaceutical preparations; Chemico-pharmaceutical preparations; Stem cells for medical purposes; Stem cells for veterinary purposes; Cultures for medical use; Cultures for veterinary use; Cellular function activating agents for medical purposes; Surgical implants grown from stem cells; Transplants [living tissues]; Pharmaceutical agents for treating physically caused lesions; Homeopathic pharmaceuticals; Mineral food supplements; plasters; Materials for dressings; Material for stopping teeth, dental wax; Disinfectants; Herbicides; Fungicides. Medical services; Medical services; Medical services in the field of treatment of chronic pain; Advisory services relating to degenerative diseases; Psychological counseling; Psychiatric services; Performing diagnosis of diseases; Medical testing services relating to the diagnosis and treatment of disease; Alternative medicine services; Stem cell storage; Medical services relating to the removal, treatment and processing of stem cells; Medical services relating to the removal, treatment and processing of bone marrow; Analysis of human tissues for medical treatment; Cosmetic treatment; Veterinary services; Development of individual physical rehabilitation programmes; Advice relating to the personal welfare of elderly people [health]; Medical equipment rental.
6.
Biomaterial scaffold for regenerating the oral mucosa
The present invention refers to a process for preparing a biomaterial scaffold said method comprising, (a) providing a hydrogel comprising a fibrin network and a polysaccharide network; (b) subjecting the hydrogel of step a) to a freeze-thawing process to physically crosslink the hydrogel; and (c) subjecting the physically cross-linked hydrogel obtained after conducting the step b), to a lyophilization. The invention also relates to the biomaterial scaffold obtainable by the process as defined above, as well said biomaterial scaffold for its use to partially or completely increase, restore or replace the functional activity of a diseased or damaged oral mucosa.
The present invention relates to an antioxidant composition comprising a combination of galatomannan and N-acetyl cysteine for its use in the treatment of a skin disease or condition resulting from reactive oxygen species production in the skin or involving reactive oxygen species production in the skin, to a hydrogel containing said combination as well as to dressing wounds comprising said hydrogel and its use in the healing of ulcers, wounds, burns and scalds.
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
A61K 35/30 - NerfsCerveauYeuxCellules cornéennesLiquide céphalorachidienCellules souches neuronalesCellules précurseurs neuronalesCellules glialesOligodendrocytesCellules de SchwannAstrogliesAstrocytesPlexus choroïdeTissu de moelle épinière
A61K 8/46 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant du soufre
A61K 8/98 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés d'origine animale
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
8.
A BIOMATERIAL SCAFFOLD FOR REGENERATING THE ORAL MUCOSA
The present invention refers to a process for preparing a biomaterial scaffold said method comprising, (a) providing a hydrogel comprising a fibrin network and a polysaccharide network; (b) subjecting the hydrogel of step a) to a freeze-thawing process to physically crosslink the hydrogel; and (c) subjecting the physically cross-linked hydrogel obtained after conducting the step b), to a lyophilization. The invention also relates to the biomaterial scaffold obtainable by the process as defined above, as well said biomaterial scaffold for its use to partially or completely increase, restore or replace the functional activity of a diseased or damaged oral mucosa.
The present invention refers to a process for preparing a biomaterial scaffold said method comprising, (a) providing a hydrogel comprising a fibrin network and a polysaccharide network; (b) subjecting the hydrogel of step a) to a freeze-thawing process to physically crosslink the hydrogel; and (c) subjecting the physically cross-linked hydrogel obtained after conducting the step b), to a lyophilization. The invention also relates to the biomaterial scaffold obtainable by the process as defined above, as well said biomaterial scaffold for its use to partially or completely increase, restore or replace the functional activity of a diseased or damaged oral mucosa.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical and veterinary products; medicinal oils;
amino acids for medical purposes, amino acids for veterinary
purposes; diagnostic products for medical use;
bacteriological culture media; bacteriological preparations
for medical or veterinary use; implantable materials for use
in guided tissue regeneration, regenerative tissue
[pharmaceutical preparations]; sanitary preparations for
medical purposes, medicines for dental purposes; medical
dressings, items for dressings; therapeutic creams
[medicated]; organotherapy preparations, opotherapy
products; dietetic substances for medical use, food for
babies; edible non-nutritive plant fibers; nutritional
additives for medical purposes, mineral food supplements;
preparations of microorganisms for medical and veterinary
use; fish meal for pharmaceutical purposes; fungicides,
herbicides, products for destroying vermin. Surgical, medical, dental and veterinary apparatus and
instruments, as well as artificial limbs, eyes and teeth;
orthopedic articles; suture materials; diagnostic apparatus
for medical purposes, detection instruments for veterinary
use, veterinary diagnostic tools; lasers for medical
purposes, lasers with veterinary purposes; supportive
bandages. Medical services, psychology services, telemedicine
services, health services, dentistry, therapeutic services;
veterinary services; surgery; medical analyses; analysis of
human tissues for medical treatment; animal breeding;
updating of personal medical records registers and archives;
rental of medical equipment; cosmetic surgery, aesthetic
surgery; cosmetic treatment, cosmetic consultancy,
beautician services; hygiene and beauty care for humans or
animals; development of individual physical rehabilitation
programs; rehabilitation for substance abuse patients;
advice concerning personal well-being in the elderly
[health]; preparation and dispensing of medicines; providing
home health care services; providing mental rehabilitation
facilities; nursing homes; elimination of vermin for
agriculture, horticulture and forestry.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical and veterinary preparations; Medicinal oils; Amino acids for medical purposes, amino acids for veterinary purposes; Diagnostic preparations; Mediums (Bacteriological culture -); Bacteriological preparations for medical and veterinary use; Implantable materials for use in guided tissue regeneration, Regenerative tissue (pharmaceutical preparations); Sanitary preparations for medical purposes, Medicines for dental purposes; Dressings, medical, Dressings, medical; Therapeutic creams [medical]; Organotherapy preparations, Organotherapy preparations; Dietetic substances adapted for medical use, food for babies; Edible, non-nutritive plant fibres; Nutritional additives for medical purposes, mineral food-supplements; Cultures of microorganisms for medical and veterinary use; Fish meal for pharmaceutical purposes; Fungicides, Herbicides, Preparations for destroying vermin. Surgical, medical, dental and veterinary apparatus and instruments, artificial limbs, eyes and teeth; Orthopedic articles; Suture materials; Diagnostic apparatus for medical purposes, Detecting instruments for veterinary use, Tools for veterinary diagnostics; Lasers for medical purposes, Lasers for veterinary purposes; Bandages for joints, anatomical. Medical services, Psychologist (Services of a -), Telemedicine services, Human healthcare services, Dentistry, Therapy services; Veterinary services; Surgery; Medical screening; Analysis of human tissues for medical treatment; Farming (animals); Maintaining personal medical history records and files; Medical equipment rental; Surgery (Cosmetic -), Plastic surgery; Cosmetic treatment, Consultancy services relating to cosmetics, Beauty salons; Hygiene and beauty care for people or animals; Development of individual physical rehabilitation programmes; Rehabilitation for substance abuse patients; Advice relating to the personal welfare of elderly people [health]; Preparation and dispensing of medications; Provision of health care services in domestic homes; Providing mental rehabilitation facilities; Nursing homes; Vermin exterminating for agriculture, horticulture and forestry.
12.
Treatment method for mesenchymal stem cells and their application as a treatment of oxidative stress related diseases
The present invention relates to a method of treatment of mesenchymal stem cells, preferably from adipose origin, comprising mainly two stages, firstly the collection and isolation of mesenchymal stem cells, and secondly, a period of growth and specific treatment of cells in a conditioning or treatment medium with an oxidizing agent. The invention also comprises the cells obtained directly through the method and its use in treating diseases caused by or associated with oxidative stress.
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
03 - Produits cosmétiques et préparations de toilette; préparations pour blanchir, nettoyer, polir et abraser.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
35 - Publicité; Affaires commerciales
Produits et services
Oils for toilet purposes, oils for cosmetic purposes; Soaps; Perfumery products, Ethereal oils, Cosmetics, Cosmetic creams, Cosmetic dyes, Hair lotions; Tissues impregnated with cosmetic lotions, Adhesives for cosmetic purposes. Pharmaceutical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for humans and animals; Plasters, materials for dressings; Material for stopping teeth, dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; Diagnostic preparations for medical purposes; Bacterial and bacteriological preparations for medical or veterinary purposes; Implantable materials for use in guided tissue regeneration, Regenerative tissue (pharmaceutical preparations); Disinfectant dressings, Wound dressing; Medicinal creams for protection of the skin, Therapeutic creams (medicated); Organ therapeutic preparations, Opotherapy preparations; Immunotherapeutic agents for bacterial infections; Cultures of micro-organisms for medical and veterinary use. Sales promotion for others; Business representative services; Presentation of goods on communication media, for retail purposes; Retailing of cosmetics and perfumery, dietary supplements, food and vitamin preparations for the pharmaceutical and healthcare sector, pharmaceutical and veterinary preparations, dressings and bandages, regenerative tissue, bacteriological preparations, sanitary preparations for medical and veterinary purposes, parapharmaceuticals, disinfectants, fungicides and herbicides, medical and veterinary apparatus and instruments, apparatus and instruments for therapeutic and diagnostic purposes; Business management assistance; Outsourcing services (business assistance); Advertising; Commercial administration of the licensing of the goods and services of others; Business consultancy relating to franchising; Organisation of trade fairs and exhibitions for commercial and advertising purposes.
The present invention relates to a biomaterial, specifically a hydrogel, based on the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans present exclusively in the Wharton's jelly of the umbilical cord (which can optionally be combined with cells as a combination therapy), and also to the methods for the production and use thereof.
A61K 8/98 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés d'origine animale
A61L 27/26 - Mélanges de matériaux macromoléculaires
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
The present invention relates to an antioxidant composition comprising a combination of galatomannan and N-acetyl cysteine for its use in the treatment of a skin disease or condition resulting from reactive oxygen species production in the skin or involving reactive oxygen species production in the skin, to a hydrogel containing said combination as well as to dressing wounds comprising said hydrogel and its use in the healing of ulcers, wounds, burns and scalds.
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
A61K 35/30 - NerfsCerveauYeuxCellules cornéennesLiquide céphalorachidienCellules souches neuronalesCellules précurseurs neuronalesCellules glialesOligodendrocytesCellules de SchwannAstrogliesAstrocytesPlexus choroïdeTissu de moelle épinière
The present invention relates to a method of treatment of mesenchymal stem cells, preferably from adipose origin, comprising mainly two stages, firstly the collection and isolation of mesenchymal stem cells, and secondly, a period of growth and specific treatment of cells in a conditioning or treatment medium with an oxidizing agent. The invention also comprises the cells obtained directly through the method and its use in treating diseases caused by or associated with oxidative stress.
The present invention relates, first, to a method for processing mesenchymal stem cells, preferably of adipose origin, which basically comprises two steps, namely the production and isolation of mesenchymal cells, and, second, a step of growth and specific processing of the cells in a conditioning or processing medium with an oxidizing agent. The invention also comprises the cells obtained directly by means of the method and the use of said cells in the treatment of diseases caused by or associated with oxidative stress.
The present invention relates to an antioxidant composition that comprises a combination of galactomannan and N-acetylcysteine for use in the treatment of a skin disease or condition that is the result of the production of reactive oxygen species in the skin or that involves the production of reactive oxygen species in the skin. The invention also relates to a hydrogel containing said combination, to wound dressings that comprise said hydrogel, and to the use thereof in the healing of ulcers, wounds, burns and scalds.
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
A61P 17/16 - Émollients ou protecteurs, p. ex. contre les radiations
The present invention relates to an antioxidant composition comprising a combination of galatomannan and N-acetyl cysteine for its use in the treatment of a skin disease or condition resulting from reactive oxygen species production in the skin or involving reactive oxygen species production in the skin, to a hydrogel containing said combination as well as to dressing wounds comprising said hydrogel and its use in the healing of ulcers, wounds, burns and scalds.
A61L 15/60 - Matériaux gonflant avec les liquides pour former un gel, p. ex. super-absorbants
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
A61P 17/16 - Émollients ou protecteurs, p. ex. contre les radiations
A61Q 17/04 - Préparations topiques pour faire écran au soleil ou aux radiationsPréparations topiques pour bronzer
20.
Biomaterial based on Wharton's jelly from the human umbilical cord
The present invention relates to a biomaterial, specifically a hydrogel, formed from the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans isolated exclusively from the Wharton's jelly of the umbilical cord which can optionally contain cells, and also to the methods for the production and use thereof.
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
C12N 5/02 - Propagation de cellules individuelles ou de cellules en suspensionLeur conservationMilieux de culture à cet effet
The present invention relates to a biomaterial, specifically a hydrogel, based on the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans present exclusively in the Wharton' s jelly of the umbilical cord (which can optionally be combined with cells as a combination therapy), and also to the methods for the production and use thereof.
The present invention relates to a biomaterial, specifically a hydrogel, based on the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans present exclusively in the Wharton' s jelly of the umbilical cord (which can optionally be combined with cells as a combination therapy), and also to the methods for the production and use thereof.
The present invention is comprised within tissue engineering and, specifically, within bone regeneration. The invention relates to a porous three-dimensional matrix of monetite which is biocompatible, has structured porosity and is predefined and reabsorbable, as well as to the method of synthesis capable of producing said material and the applications thereof. These matrices are a perfect base for cell colonization and proliferation, allowing the application thereof in tissue engineering and bone regeneration as a result of their advantageous properties of biocompatibility, reabsorption, osteoinduction, revascularization, etc.
A01N 63/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des micro-organismes, des virus, des champignons microscopiques, des animaux ou des substances produites par, ou obtenues à partir de micro-organismes, de virus, de champignons microscopiques ou d'animaux, p. ex. enzymes ou produits de fermentation
A61L 27/12 - Matériaux contenant du phosphore, p. ex. apatite
The present invention relates to a system for cell transport Said system allows the transport of cells, assuring their integrity and viability during the entire transport process. It consists of a system suitable for a wide variety of formats which allows a broad range of technical applications of the system The system of the invention allows providing ready-to-use cells, without the cells having to be manipulated before they are used by technical experts in cell biology The invention particularly relates to an agarose plus agarase mixture covering or enveloping, depending on the format of the selected transport system, the cell culture, protecting it during the transport process, as well as to the methodology of cell recovery of the cells transported in the system.
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
25.
NEW BIOMATERIAL BASED ON WHARTON'S JELLY FROM THE HUMAN UMBILICAL CORD
The invention relates to a biomaterial, specifically a hydrogel, made from the extracellular matrix of the umbilical cord for use in Regenerative Medicine. In particular, the invention relates to a biomaterial made up of glycosaminoglycans isolated exclusively from the Wharton's jelly of the umbilical cord, which biomaterial may optionally contain cells, and also to methods for the production and use thereof.
A61L 27/44 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire
The present invention is in the field of tissue engineering and, specifically, that of osseous regeneration. The invention relates to a porous three-dimensional matrix of biocompatible monetite, of predefined structured porosity and reabsorbable, and method of synthesis capable of producing said material and applications thereof. These matrices constitute a perfect base for cell colonisation and proliferation permitting application thereof in tissue engineering and osseous regeneration by virtue of their advantageous properties of biocompatibility, reabsorption, osteoinduction, revascularisation, etc.
The present invention is comprised within tissue engineering and, specifically, within bone regeneration. The invention relates to a porous three-dimensional matrix of monetite which is biocompatible, has structured porosity and is predefined and reabsorbable, as well as to the method of synthesis capable of producing said material and the applications thereof. These matrices are a perfect base for cell colonization and proliferation, allowing the application thereof in tissue engineering and bone regeneration as a result of their advantageous properties of biocompatibility, reabsorption, osteoinduction, revascularization, etc.
The present invention is in the field of tissue engineering and, specifically, that of osseous regeneration. The invention relates to a porous three-dimensional matrix of biocompatible monetite, of defined porosity and biodegradable, and the method of synthesis capable of producing said material and applications thereof. These matrices constitute a perfect base for cell colonisation and proliferation permitting application thereof in tissue engineering and osseous regeneration by virtue of their advantageous properties of biocompatibility, reabsorption, osteoinduction, revascularisation, etc.
