Noray BG

United States of America

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2022 1
2021 2
Before 2021 25
IPC Class
A61K 31/736 - Glucomannans or galactomannans, e.g locust bean gum, guar gum 7
A61K 8/73 - Polysaccharides 6
A61F 2/02 - Prostheses implantable into the body 5
A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells 5
A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger 5
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NICE Class
05 - Pharmaceutical, veterinary and sanitary products 5
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services 4
10 - Medical apparatus and instruments 2
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations 1
35 - Advertising and business services 1
Status
Pending 1
Registered / In Force 27

1.

NEW ANTIOXIDANT COMPOSITION FOR WOUND HEALING

      
Application Number 17629229
Status Pending
Filing Date 2019-07-24
First Publication Date 2022-10-06
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Herrero De Miguel, Jone
  • Castro Feo, Maria Begona
  • Bastida Corcuera, Felix Daniel

Abstract

The present invention is comprised in the cosmetic and/or therapeutic industry and specifically relates to a new composition for topical use with antioxidant and hydrating activity which promotes wound healing and is useful in therapeutic and/or cosmetic treatment, as well as in the prevention of skin lesions. The present invention is comprised in the cosmetic and/or therapeutic industry and specifically relates to a new composition for topical use with antioxidant and hydrating activity which promotes wound healing and is useful in therapeutic and/or cosmetic treatment, as well as in the prevention of skin lesions. The novel composition object of the present invention incorporates certain agents and ingredients, among which are carotenoids and the galactomannans, which surprisingly improve the healing and curing activity in a broad spectrum of wounds occurring with the presence of reactive oxygen species.

IPC Classes  ?

  • A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
  • A61K 31/01 - Hydrocarbons
  • A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
  • A61K 31/047 - Hydroxy compounds, e.g. alcoholsSalts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
  • A61K 31/015 - Hydrocarbons carbocyclic
  • A61K 31/736 - Glucomannans or galactomannans, e.g locust bean gum, guar gum
  • A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
  • A61K 9/06 - OintmentsBases therefor
  • A61K 9/00 - Medicinal preparations characterised by special physical form

2.

NEW ANTIOXIDANT COMPOSITION FOR WOUND HEALING

      
Application Number ES2019070520
Publication Number 2021/014032
Status In Force
Filing Date 2019-07-24
Publication Date 2021-01-28
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Herrero De Miguel, Jone
  • Castro Feo, María Begoña
  • Bastida Corcuera, Felix Daniel

Abstract

The present invention is intended for use in the cosmetic and/or therapeutic industry and specifically relates to a new composition for topical use with antioxidant and hydrating activity which promotes wound healing and is suitable for use in the therapeutic and/or cosmetic treatment, and also prevention, of skin lesions. The novel composition of the present invention incorporates certain agents and ingredients, including carotenoids and galactomannans, which dramatically improve the healing and curing activity across a broad spectrum of wounds associated with the presence of reactive oxygen species.

IPC Classes  ?

  • A61L 26/00 - Chemical aspects of, or use of materials for, liquid bandages
  • A23L 5/44 - Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
  • A61K 8/73 - Polysaccharides
  • A61K 31/01 - Hydrocarbons
  • A61K 31/736 - Glucomannans or galactomannans, e.g locust bean gum, guar gum
  • A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

3.

ANTIOXIDANT COMPOSITION FOR WOUND HEALING

      
Document Number 03143472
Status In Force
Filing Date 2019-07-24
Open to Public Date 2021-01-28
Grant Date 2025-07-29
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Herrero De Miguel, Jone
  • Castro Feo, Maria Begona
  • Bastida Corcuera, Felix Daniel

Abstract

The present invention is comprised in the cosmetic and/or therapeutic industry and specifically relates to a new composition for topical use with antioxidant and hydrating activity which promotes wound healing and is useful in therapeutic and/or cosmetic treatment, as well as in the prevention of skin lesions. The novel composition object of the present invention incorporates certain agents and ingredients, among which are carotenoids and the galactomannans, which surprisingly improve the healing and curing activity in a broad spectrum of wounds occurring with the presence of reactive oxygen species.

IPC Classes  ?

  • A23L 5/44 - Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
  • A61K 8/73 - Polysaccharides
  • A61K 31/01 - Hydrocarbons
  • A61K 31/736 - Glucomannans or galactomannans, e.g locust bean gum, guar gum
  • A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
  • A61L 26/00 - Chemical aspects of, or use of materials for, liquid bandages

4.

HISTOESSENCE

      
Application Number 017938696
Status Registered
Filing Date 2018-08-02
Registration Date 2018-12-05
Owner HISTOCELL, S.L. (Spain)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations for medical and veterinary use; Sanitary preparations for medical purposes; Chemico-pharmaceutical preparations; Skin care preparations for medical use; Pharmaceutical preparations for skin care; Antimicrobials for dermatologic use; Stem cells for medical purposes; Stem cells for veterinary purposes; Cultures for medical use; Cultures for veterinary use; Cellular function activating agents for medical purposes; Surgical implants grown from stem cells; Transplants [living tissues]; Bandages for skin wounds; Pharmaceutical agents for treating physically caused lesions; Surgical plasters; Materials for dressings; Homeopathic pharmaceuticals; Dietetic food and substances adapted for medical or veterinary use, food for babies; Food supplements for human beings and animals; Mineral food supplements; Material for stopping teeth, dental wax; Teeth filling material; Dietary supplements with a cosmetic effect; Disinfectants; Preparations for destroying vermin; Herbicides; Fungicides. Medical services; Medical services; Medical services in the field of treatment of chronic pain; Advisory services relating to degenerative diseases; Providing medical advice in the field of dermatology; Dermatological services for treating skin conditions; Consultancy services relating to cosmetics; Psychological counseling; Psychiatric services; Performing diagnosis of diseases; Medical testing services relating to the diagnosis and treatment of disease; Alternative medicine services; Stem cell storage; Medical services relating to the removal, treatment and processing of stem cells; Medical services relating to the removal, treatment and processing of bone marrow; Analysis of human tissues for medical treatment; Cosmetic treatment; Veterinary services; Human hygiene and beauty care; Hygienic and beauty care for animals; Development of individual physical rehabilitation programmes; Advice relating to the personal welfare of elderly people [health]; Agriculture, horticulture and forestry services; Providing information about agriculture, horticulture, and forestry services; Medical equipment rental.

5.

NEUROSAVE

      
Application Number 017907304
Status Registered
Filing Date 2018-05-28
Registration Date 2018-11-17
Owner HISTOCELL, S.L. (Spain)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations for medical and veterinary use; Sanitary preparations for medical purposes; Pharmaceutical preparations; Chemico-pharmaceutical preparations; Stem cells for medical purposes; Stem cells for veterinary purposes; Cultures for medical use; Cultures for veterinary use; Cellular function activating agents for medical purposes; Surgical implants grown from stem cells; Transplants [living tissues]; Pharmaceutical agents for treating physically caused lesions; Homeopathic pharmaceuticals; Mineral food supplements; plasters; Materials for dressings; Material for stopping teeth, dental wax; Disinfectants; Herbicides; Fungicides. Medical services; Medical services; Medical services in the field of treatment of chronic pain; Advisory services relating to degenerative diseases; Psychological counseling; Psychiatric services; Performing diagnosis of diseases; Medical testing services relating to the diagnosis and treatment of disease; Alternative medicine services; Stem cell storage; Medical services relating to the removal, treatment and processing of stem cells; Medical services relating to the removal, treatment and processing of bone marrow; Analysis of human tissues for medical treatment; Cosmetic treatment; Veterinary services; Development of individual physical rehabilitation programmes; Advice relating to the personal welfare of elderly people [health]; Medical equipment rental.

6.

Biomaterial scaffold for regenerating the oral mucosa

      
Application Number 15520986
Grant Number 11241516
Status In Force
Filing Date 2015-10-23
First Publication Date 2017-11-30
Grant Date 2022-02-08
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Castro Feo, María Begoña
  • Baiget Orts, Amparo

Abstract

The present invention refers to a process for preparing a biomaterial scaffold said method comprising, (a) providing a hydrogel comprising a fibrin network and a polysaccharide network; (b) subjecting the hydrogel of step a) to a freeze-thawing process to physically crosslink the hydrogel; and (c) subjecting the physically cross-linked hydrogel obtained after conducting the step b), to a lyophilization. The invention also relates to the biomaterial scaffold obtainable by the process as defined above, as well said biomaterial scaffold for its use to partially or completely increase, restore or replace the functional activity of a diseased or damaged oral mucosa.

IPC Classes  ?

7.

Antioxidant composition

      
Application Number 15283759
Grant Number 10231992
Status In Force
Filing Date 2016-10-03
First Publication Date 2017-01-26
Grant Date 2019-03-19
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Castro Feo, María Begoña
  • Azcoitia Ramsden, Iker
  • Palomares Casado, Teodoro
  • Herrero De Miguel, Jone
  • Alonso Varona, Ana Isabel
  • Del Olmo Basterrechea, Maite

Abstract

The present invention relates to an antioxidant composition comprising a combination of galatomannan and N-acetyl cysteine for its use in the treatment of a skin disease or condition resulting from reactive oxygen species production in the skin or involving reactive oxygen species production in the skin, to a hydrogel containing said combination as well as to dressing wounds comprising said hydrogel and its use in the healing of ulcers, wounds, burns and scalds.

IPC Classes  ?

  • A61K 8/00 - Cosmetics or similar toiletry preparations
  • A61K 31/736 - Glucomannans or galactomannans, e.g locust bean gum, guar gum
  • A61K 31/12 - Ketones
  • A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
  • A61K 36/483 - Gleditsia (locust)
  • A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
  • A61K 35/33 - Fibroblasts
  • A61K 8/73 - Polysaccharides
  • A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
  • A61K 35/30 - NervesBrainEyesCorneal cellsCerebrospinal fluidNeuronal stem cellsNeuronal precursor cellsGlial cellsOligodendrocytesSchwann cellsAstrogliaAstrocytesChoroid plexusSpinal cord tissue
  • A61K 35/32 - BonesOsteocytesOsteoblastsTendonsTenocytesTeethOdontoblastsCartilageChondrocytesSynovial membrane
  • A61K 35/36 - SkinHairNailsSebaceous glandsCerumenEpidermisEpithelial cellsKeratinocytesLangerhans cellsEctodermal cells
  • A61Q 19/00 - Preparations for care of the skin
  • A61K 8/35 - Ketones, e.g. quinones, benzophenone
  • A61K 8/44 - Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfurSalts, esters or N-acylated derivatives thereof
  • A61Q 17/04 - Topical preparations for affording protection against sunlight or other radiationTopical sun tanning preparations
  • A61Q 19/08 - Anti-ageing preparations
  • A61K 8/04 - DispersionsEmulsions
  • A61K 8/46 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
  • A61K 8/98 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution of animal origin
  • A61K 9/00 - Medicinal preparations characterised by special physical form

8.

A BIOMATERIAL SCAFFOLD FOR REGENERATING THE ORAL MUCOSA

      
Document Number 02964501
Status In Force
Filing Date 2015-10-23
Open to Public Date 2016-04-28
Grant Date 2023-05-16
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Castro Feo, Begona
  • Baiget Orts, Amparo

Abstract

The present invention refers to a process for preparing a biomaterial scaffold said method comprising, (a) providing a hydrogel comprising a fibrin network and a polysaccharide network; (b) subjecting the hydrogel of step a) to a freeze-thawing process to physically crosslink the hydrogel; and (c) subjecting the physically cross-linked hydrogel obtained after conducting the step b), to a lyophilization. The invention also relates to the biomaterial scaffold obtainable by the process as defined above, as well said biomaterial scaffold for its use to partially or completely increase, restore or replace the functional activity of a diseased or damaged oral mucosa.

IPC Classes  ?

9.

A BIOMATERIAL SCAFFOLD FOR REGENERATING THE ORAL MUCOSA

      
Application Number EP2015074610
Publication Number 2016/062862
Status In Force
Filing Date 2015-10-23
Publication Date 2016-04-28
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Castro Feo, Begoña
  • Baiget Orts, Amparo

Abstract

The present invention refers to a process for preparing a biomaterial scaffold said method comprising, (a) providing a hydrogel comprising a fibrin network and a polysaccharide network; (b) subjecting the hydrogel of step a) to a freeze-thawing process to physically crosslink the hydrogel; and (c) subjecting the physically cross-linked hydrogel obtained after conducting the step b), to a lyophilization. The invention also relates to the biomaterial scaffold obtainable by the process as defined above, as well said biomaterial scaffold for its use to partially or completely increase, restore or replace the functional activity of a diseased or damaged oral mucosa.

IPC Classes  ?

10.

Reoxcare

      
Application Number 1271121
Status Registered
Filing Date 2015-07-30
Registration Date 2015-07-30
Owner HISTOCELL, S.L. (Spain)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical and veterinary products; medicinal oils; amino acids for medical purposes, amino acids for veterinary purposes; diagnostic products for medical use; bacteriological culture media; bacteriological preparations for medical or veterinary use; implantable materials for use in guided tissue regeneration, regenerative tissue [pharmaceutical preparations]; sanitary preparations for medical purposes, medicines for dental purposes; medical dressings, items for dressings; therapeutic creams [medicated]; organotherapy preparations, opotherapy products; dietetic substances for medical use, food for babies; edible non-nutritive plant fibers; nutritional additives for medical purposes, mineral food supplements; preparations of microorganisms for medical and veterinary use; fish meal for pharmaceutical purposes; fungicides, herbicides, products for destroying vermin. Surgical, medical, dental and veterinary apparatus and instruments, as well as artificial limbs, eyes and teeth; orthopedic articles; suture materials; diagnostic apparatus for medical purposes, detection instruments for veterinary use, veterinary diagnostic tools; lasers for medical purposes, lasers with veterinary purposes; supportive bandages. Medical services, psychology services, telemedicine services, health services, dentistry, therapeutic services; veterinary services; surgery; medical analyses; analysis of human tissues for medical treatment; animal breeding; updating of personal medical records registers and archives; rental of medical equipment; cosmetic surgery, aesthetic surgery; cosmetic treatment, cosmetic consultancy, beautician services; hygiene and beauty care for humans or animals; development of individual physical rehabilitation programs; rehabilitation for substance abuse patients; advice concerning personal well-being in the elderly [health]; preparation and dispensing of medicines; providing home health care services; providing mental rehabilitation facilities; nursing homes; elimination of vermin for agriculture, horticulture and forestry.

11.

Reoxcare

      
Application Number 013287651
Status Registered
Filing Date 2014-09-22
Registration Date 2015-02-12
Owner HISTOCELL, S.L. (Spain)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical and veterinary preparations; Medicinal oils; Amino acids for medical purposes, amino acids for veterinary purposes; Diagnostic preparations; Mediums (Bacteriological culture -); Bacteriological preparations for medical and veterinary use; Implantable materials for use in guided tissue regeneration, Regenerative tissue (pharmaceutical preparations); Sanitary preparations for medical purposes, Medicines for dental purposes; Dressings, medical, Dressings, medical; Therapeutic creams [medical]; Organotherapy preparations, Organotherapy preparations; Dietetic substances adapted for medical use, food for babies; Edible, non-nutritive plant fibres; Nutritional additives for medical purposes, mineral food-supplements; Cultures of microorganisms for medical and veterinary use; Fish meal for pharmaceutical purposes; Fungicides, Herbicides, Preparations for destroying vermin. Surgical, medical, dental and veterinary apparatus and instruments, artificial limbs, eyes and teeth; Orthopedic articles; Suture materials; Diagnostic apparatus for medical purposes, Detecting instruments for veterinary use, Tools for veterinary diagnostics; Lasers for medical purposes, Lasers for veterinary purposes; Bandages for joints, anatomical. Medical services, Psychologist (Services of a -), Telemedicine services, Human healthcare services, Dentistry, Therapy services; Veterinary services; Surgery; Medical screening; Analysis of human tissues for medical treatment; Farming (animals); Maintaining personal medical history records and files; Medical equipment rental; Surgery (Cosmetic -), Plastic surgery; Cosmetic treatment, Consultancy services relating to cosmetics, Beauty salons; Hygiene and beauty care for people or animals; Development of individual physical rehabilitation programmes; Rehabilitation for substance abuse patients; Advice relating to the personal welfare of elderly people [health]; Preparation and dispensing of medications; Provision of health care services in domestic homes; Providing mental rehabilitation facilities; Nursing homes; Vermin exterminating for agriculture, horticulture and forestry.

12.

Treatment method for mesenchymal stem cells and their application as a treatment of oxidative stress related diseases

      
Application Number 14131049
Grant Number 09080153
Status In Force
Filing Date 2011-07-06
First Publication Date 2014-06-05
Grant Date 2015-07-14
Owner HISTOCELL S.L. (Spain)
Inventor
  • Castro, Maria Begona
  • Diez Garcia, Javier

Abstract

The present invention relates to a method of treatment of mesenchymal stem cells, preferably from adipose origin, comprising mainly two stages, firstly the collection and isolation of mesenchymal stem cells, and secondly, a period of growth and specific treatment of cells in a conditioning or treatment medium with an oxidizing agent. The invention also comprises the cells obtained directly through the method and its use in treating diseases caused by or associated with oxidative stress.

IPC Classes  ?

  • A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
  • C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells
  • A61K 35/28 - Bone marrowHaematopoietic stem cellsMesenchymal stem cells of any origin, e.g. adipose-derived stem cells

13.

Wharton Gel Complex

      
Application Number 012065314
Status Registered
Filing Date 2013-08-14
Registration Date 2014-01-08
Owner HISTOCELL, S.L. (Spain)
NICE Classes  ?
  • 03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 35 - Advertising and business services

Goods & Services

Oils for toilet purposes, oils for cosmetic purposes; Soaps; Perfumery products, Ethereal oils, Cosmetics, Cosmetic creams, Cosmetic dyes, Hair lotions; Tissues impregnated with cosmetic lotions, Adhesives for cosmetic purposes. Pharmaceutical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for humans and animals; Plasters, materials for dressings; Material for stopping teeth, dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; Diagnostic preparations for medical purposes; Bacterial and bacteriological preparations for medical or veterinary purposes; Implantable materials for use in guided tissue regeneration, Regenerative tissue (pharmaceutical preparations); Disinfectant dressings, Wound dressing; Medicinal creams for protection of the skin, Therapeutic creams (medicated); Organ therapeutic preparations, Opotherapy preparations; Immunotherapeutic agents for bacterial infections; Cultures of micro-organisms for medical and veterinary use. Sales promotion for others; Business representative services; Presentation of goods on communication media, for retail purposes; Retailing of cosmetics and perfumery, dietary supplements, food and vitamin preparations for the pharmaceutical and healthcare sector, pharmaceutical and veterinary preparations, dressings and bandages, regenerative tissue, bacteriological preparations, sanitary preparations for medical and veterinary purposes, parapharmaceuticals, disinfectants, fungicides and herbicides, medical and veterinary apparatus and instruments, apparatus and instruments for therapeutic and diagnostic purposes; Business management assistance; Outsourcing services (business assistance); Advertising; Commercial administration of the licensing of the goods and services of others; Business consultancy relating to franchising; Organisation of trade fairs and exhibitions for commercial and advertising purposes.

14.

Biomaterial from Wharton's jelly umbilical cord

      
Application Number 13638535
Grant Number 10226480
Status In Force
Filing Date 2010-03-30
First Publication Date 2013-04-18
Grant Date 2019-03-12
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Font Perez, Julio
  • Castro Feo, Maria Begoña
  • Del Olmo Basterrechea, Maite

Abstract

The present invention relates to a biomaterial, specifically a hydrogel, based on the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans present exclusively in the Wharton's jelly of the umbilical cord (which can optionally be combined with cells as a combination therapy), and also to the methods for the production and use thereof.

IPC Classes  ?

  • A61K 31/726 - Glycosaminoglycans, i.e. mucopolysaccharides
  • A61K 8/04 - DispersionsEmulsions
  • A61K 8/98 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution of animal origin
  • A61L 27/26 - Mixtures of macromolecular materials
  • A61L 27/56 - Porous or cellular materials
  • A61L 27/52 - Hydrogels or hydrocolloids
  • A61K 35/30 - NervesBrainEyesCorneal cellsCerebrospinal fluidNeuronal stem cellsNeuronal precursor cellsGlial cellsOligodendrocytesSchwann cellsAstrogliaAstrocytesChoroid plexusSpinal cord tissue
  • A61K 35/14 - BloodArtificial blood
  • A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
  • A61K 31/727 - HeparinHeparan
  • A61Q 19/08 - Anti-ageing preparations
  • A61K 8/73 - Polysaccharides
  • A61K 35/44 - VesselsVascular smooth muscle cellsEndothelial cellsEndothelial progenitor cells
  • A61K 35/36 - SkinHairNailsSebaceous glandsCerumenEpidermisEpithelial cellsKeratinocytesLangerhans cellsEctodermal cells
  • A61K 35/35 - Fat tissueAdipocytesStromal cellsConnective tissues
  • A61K 35/34 - MusclesSmooth muscle cellsHeartCardiac stem cellsMyoblastsMyocytesCardiomyocytes
  • A61K 35/33 - Fibroblasts
  • A61K 35/32 - BonesOsteocytesOsteoblastsTendonsTenocytesTeethOdontoblastsCartilageChondrocytesSynovial membrane
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/06 - OintmentsBases therefor
  • A61K 31/737 - Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
  • A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
  • A61K 31/728 - Hyaluronic acid
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

15.

Antioxidant composition

      
Application Number 13704207
Grant Number 09492475
Status In Force
Filing Date 2011-06-14
First Publication Date 2013-04-18
Grant Date 2016-11-15
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Castro Feo, Maria Begoña
  • Azcoitia Ramsden, Iker
  • Palomares Casado, Teodoro
  • Herrero De Miguel, Jone
  • Alonso Varona, Ana Isabel
  • Del Olmo Basterrechea, Maite

Abstract

The present invention relates to an antioxidant composition comprising a combination of galatomannan and N-acetyl cysteine for its use in the treatment of a skin disease or condition resulting from reactive oxygen species production in the skin or involving reactive oxygen species production in the skin, to a hydrogel containing said combination as well as to dressing wounds comprising said hydrogel and its use in the healing of ulcers, wounds, burns and scalds.

IPC Classes  ?

  • A61K 8/00 - Cosmetics or similar toiletry preparations
  • A61K 8/18 - Cosmetics or similar toiletry preparations characterised by the composition
  • A61Q 17/04 - Topical preparations for affording protection against sunlight or other radiationTopical sun tanning preparations
  • A61K 31/736 - Glucomannans or galactomannans, e.g locust bean gum, guar gum
  • A61K 31/12 - Ketones
  • A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
  • A61K 36/483 - Gleditsia (locust)
  • A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
  • A61K 35/33 - Fibroblasts
  • A61K 8/73 - Polysaccharides
  • A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
  • A61K 35/30 - NervesBrainEyesCorneal cellsCerebrospinal fluidNeuronal stem cellsNeuronal precursor cellsGlial cellsOligodendrocytesSchwann cellsAstrogliaAstrocytesChoroid plexusSpinal cord tissue
  • A61K 35/32 - BonesOsteocytesOsteoblastsTendonsTenocytesTeethOdontoblastsCartilageChondrocytesSynovial membrane
  • A61K 35/36 - SkinHairNailsSebaceous glandsCerumenEpidermisEpithelial cellsKeratinocytesLangerhans cellsEctodermal cells
  • A61Q 19/00 - Preparations for care of the skin

16.

A TREATMENT METHOD FOR MESENCHYMAL STEM CELLS AND THEIR APPLICATION AS A TREATMENT OF OXIDATIVE STRESS RELATED DISEASES

      
Document Number 02839106
Status In Force
Filing Date 2011-07-06
Open to Public Date 2013-01-10
Grant Date 2018-01-02
Owner HISTOCELL S.L. (Spain)
Inventor
  • Castro, Maria Begona
  • Diez Garcia, Javier

Abstract


The present invention relates to a method of treatment of mesenchymal stem
cells,
preferably from adipose origin, comprising mainly two stages, firstly the
collection and
isolation of mesenchymal stem cells, and secondly, a period of growth and
specific
treatment of cells in a conditioning or treatment medium with an oxidizing
agent. The
invention also comprises the cells obtained directly through the method and
its use in
treating diseases caused by or associated with oxidative stress.

IPC Classes  ?

  • C11D 3/39 - Organic or inorganic per-compounds
  • C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells

17.

METHOD FOR PROCESSING MESENCHYMAL STEM CELLS AND THE USE THEREOF IN THE TREATMENT OF DISEASES ASSOCIATED WITH OXIDATIVE STRESS

      
Application Number ES2011070489
Publication Number 2013/004859
Status In Force
Filing Date 2011-07-06
Publication Date 2013-01-10
Owner HISTOCELL S.L. (Spain)
Inventor
  • Castro, María Begoña
  • Díez García, Javier

Abstract

The present invention relates, first, to a method for processing mesenchymal stem cells, preferably of adipose origin, which basically comprises two steps, namely the production and isolation of mesenchymal cells, and, second, a step of growth and specific processing of the cells in a conditioning or processing medium with an oxidizing agent. The invention also comprises the cells obtained directly by means of the method and the use of said cells in the treatment of diseases caused by or associated with oxidative stress.

IPC Classes  ?

  • C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells
  • C11D 3/39 - Organic or inorganic per-compounds

18.

ANTIOXIDANT COMPOSITION

      
Application Number ES2011070427
Publication Number 2011/157880
Status In Force
Filing Date 2011-06-14
Publication Date 2011-12-22
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Castro Feo, María Begoña
  • Azcoitia Ramsden, Iker
  • Palomares Casado, Teodoro
  • Herrero De Miguel, Jone
  • Alonso Varona, Ana Isabel
  • Del Olmo Basterrechea, Maite

Abstract

The present invention relates to an antioxidant composition that comprises a combination of galactomannan and N-acetylcysteine for use in the treatment of a skin disease or condition that is the result of the production of reactive oxygen species in the skin or that involves the production of reactive oxygen species in the skin. The invention also relates to a hydrogel containing said combination, to wound dressings that comprise said hydrogel, and to the use thereof in the healing of ulcers, wounds, burns and scalds.

IPC Classes  ?

  • A61K 31/736 - Glucomannans or galactomannans, e.g locust bean gum, guar gum
  • A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
  • A61K 31/12 - Ketones
  • A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61P 17/00 - Drugs for dermatological disorders
  • A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
  • A61P 17/16 - Emollients or protectives, e.g. against radiation
  • A61P 17/06 - Antipsoriatics

19.

ANTIOXIDANT COMPOSITION COMPRISING GALACTOMANNAN AND N-ACETYL CYSTEINE

      
Document Number 02801048
Status In Force
Filing Date 2011-06-14
Open to Public Date 2011-12-22
Grant Date 2018-06-12
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Castro Feo, Maria Begona
  • Azcoitia Ramsden, Iker
  • Palomares Casado, Teodoro
  • Herrero De Miguel, Jone
  • Alonso Varona, Ana Isabel
  • Del Olmo Basterrechea, Maite

Abstract

The present invention relates to an antioxidant composition comprising a combination of galatomannan and N-acetyl cysteine for its use in the treatment of a skin disease or condition resulting from reactive oxygen species production in the skin or involving reactive oxygen species production in the skin, to a hydrogel containing said combination as well as to dressing wounds comprising said hydrogel and its use in the healing of ulcers, wounds, burns and scalds.

IPC Classes  ?

  • A61K 8/73 - Polysaccharides
  • A61K 31/12 - Ketones
  • A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
  • A61K 31/736 - Glucomannans or galactomannans, e.g locust bean gum, guar gum
  • A61L 15/28 - Polysaccharides or their derivatives
  • A61L 15/44 - Medicaments
  • A61L 15/60 - Liquid-swellable gel-forming materials, e.g. super-absorbents
  • A61P 17/00 - Drugs for dermatological disorders
  • A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
  • A61P 17/16 - Emollients or protectives, e.g. against radiation
  • A61Q 17/04 - Topical preparations for affording protection against sunlight or other radiationTopical sun tanning preparations

20.

Biomaterial based on Wharton's jelly from the human umbilical cord

      
Application Number 13123186
Grant Number 08685732
Status In Force
Filing Date 2008-10-10
First Publication Date 2011-10-20
Grant Date 2014-04-01
Owner Histocell, S.L. (Spain)
Inventor
  • Font Perez, Julio
  • Basterrechea, Maite Del Olmo
  • Castro Feo, Maria Begona
  • Infante Martinez, Arantza
  • Alonso Varona, Ana Isabel
  • Palomares Casado, Teodoro

Abstract

The present invention relates to a biomaterial, specifically a hydrogel, formed from the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans isolated exclusively from the Wharton's jelly of the umbilical cord which can optionally contain cells, and also to the methods for the production and use thereof.

IPC Classes  ?

  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
  • C12N 5/02 - Propagation of single cells or cells in suspensionMaintenance thereofCulture media therefor
  • A61F 2/02 - Prostheses implantable into the body

21.

NEW BIOMATERIAL FROM WHARTON'S JELLY UMBILICAL CORD

      
Document Number 02794315
Status In Force
Filing Date 2010-03-30
Open to Public Date 2011-10-06
Grant Date 2016-09-13
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Font Perez, Julio
  • Castro Feo, Maria Begona
  • Del Olmo Basterrechea, Maite

Abstract

The present invention relates to a biomaterial, specifically a hydrogel, based on the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans present exclusively in the Wharton' s jelly of the umbilical cord (which can optionally be combined with cells as a combination therapy), and also to the methods for the production and use thereof.

IPC Classes  ?

  • A61K 31/726 - Glycosaminoglycans, i.e. mucopolysaccharides

22.

NEW BIOMATERIAL FROM WHARTON'S JELLY UMBILICAL CORD

      
Application Number EP2010002011
Publication Number 2011/120535
Status In Force
Filing Date 2010-03-30
Publication Date 2011-10-06
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Font Perez, Julio
  • Castro Feo, Maria Begoña
  • Del Olmo Basterrechea, Maite

Abstract

The present invention relates to a biomaterial, specifically a hydrogel, based on the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans present exclusively in the Wharton' s jelly of the umbilical cord (which can optionally be combined with cells as a combination therapy), and also to the methods for the production and use thereof.

IPC Classes  ?

  • A61K 31/726 - Glycosaminoglycans, i.e. mucopolysaccharides

23.

Three-dimensional matrices of structured porous monetite for tissue engineering and bone regeneration, and method of the preparation thereof

      
Application Number 13002939
Grant Number 09320828
Status In Force
Filing Date 2009-07-08
First Publication Date 2011-06-30
Grant Date 2016-04-26
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Font Pérez, Julio
  • Castro Feo, Maria Begoña
  • Del Olmo Basterrechea, Maite
  • García Vázquez, Maria Dolores
  • Rubio Retama, Jorge
  • López Cabarcos, Enrique
  • Rueda Rodríguez, Carmen
  • Tamimi Mariño, Faleh
  • Hamdan Ali Alkhraisat, Mohammad

Abstract

The present invention is comprised within tissue engineering and, specifically, within bone regeneration. The invention relates to a porous three-dimensional matrix of monetite which is biocompatible, has structured porosity and is predefined and reabsorbable, as well as to the method of synthesis capable of producing said material and the applications thereof. These matrices are a perfect base for cell colonization and proliferation, allowing the application thereof in tissue engineering and bone regeneration as a result of their advantageous properties of biocompatibility, reabsorption, osteoinduction, revascularization, etc.

IPC Classes  ?

  • A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
  • A61L 27/12 - Phosphorus-containing materials, e.g. apatite
  • A61L 27/38 - Animal cells
  • A61L 27/56 - Porous or cellular materials
  • A61L 27/58 - Materials at least partially resorbable by the body
  • C01B 25/32 - Phosphates of magnesium, calcium, strontium, or barium
  • A61F 2/28 - Bones

24.

CELL TRANSPORT SYSTEM

      
Application Number EP2009009132
Publication Number 2010/069589
Status In Force
Filing Date 2009-12-18
Publication Date 2010-06-24
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Gartzia Aranaga, Miren Itxaso
  • Del Olmo Basterrechea, Maite
  • Castro Feo, María Begoña
  • Acilu Pérez, Marta

Abstract

The present invention relates to a system for cell transport Said system allows the transport of cells, assuring their integrity and viability during the entire transport process. It consists of a system suitable for a wide variety of formats which allows a broad range of technical applications of the system The system of the invention allows providing ready-to-use cells, without the cells having to be manipulated before they are used by technical experts in cell biology The invention particularly relates to an agarose plus agarase mixture covering or enveloping, depending on the format of the selected transport system, the cell culture, protecting it during the transport process, as well as to the methodology of cell recovery of the cells transported in the system.

IPC Classes  ?

  • A01N 1/02 - Preservation of living parts
  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor

25.

NEW BIOMATERIAL BASED ON WHARTON'S JELLY FROM THE HUMAN UMBILICAL CORD

      
Application Number ES2008000640
Publication Number 2010/040865
Status In Force
Filing Date 2008-10-10
Publication Date 2010-04-15
Owner HISTOCELL S.L. (Spain)
Inventor
  • Font Perez, Julio
  • Del Olmo Basterrechea, Maite
  • Castro Feo, Maria, Begoña
  • Infante Martinez, Arantza
  • Alonso Varona, Ana, Isabel
  • Palomares Casado, Teodoro

Abstract

The invention relates to a biomaterial, specifically a hydrogel, made from the extracellular matrix of the umbilical cord for use in Regenerative Medicine. In particular, the invention relates to a biomaterial made up of glycosaminoglycans isolated exclusively from the Wharton's jelly of the umbilical cord, which biomaterial may optionally contain cells, and also to methods for the production and use thereof.

IPC Classes  ?

  • A61F 2/02 - Prostheses implantable into the body
  • C08L 5/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof
  • C08L 5/10 - HeparinDerivatives thereof
  • A61L 27/44 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
  • A61L 27/52 - Hydrogels or hydrocolloids

26.

THREE-DIMENSIONAL MATRICES OF STRUCTURED POROUS MONETITE FOR TISSUE ENGINEERING AND OSSEOUS REGENERATION, AND METHOD FOR THE PREPARATION THEREOF

      
Application Number ES2009000358
Publication Number 2010/004066
Status In Force
Filing Date 2009-07-08
Publication Date 2010-01-14
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Font Pérez, Julio
  • Castro Feo, María Begoña
  • Del Olmo Basterrechea, Mailte
  • García Vázquez, María Dolores
  • Rubio Retama, Jorge
  • López Cabarcos, Enrique
  • Rueda Rodríguez, Carmen
  • Tamimi Mariño, Faleh
  • Hamdan Ali Alkhraisat, Mohammad

Abstract

The present invention is in the field of tissue engineering and, specifically, that of osseous regeneration. The invention relates to a porous three-dimensional matrix of biocompatible monetite, of predefined structured porosity and reabsorbable, and method of synthesis capable of producing said material and applications thereof. These matrices constitute a perfect base for cell colonisation and proliferation permitting application thereof in tissue engineering and osseous regeneration by virtue of their advantageous properties of biocompatibility, reabsorption, osteoinduction, revascularisation, etc.

IPC Classes  ?

  • C01B 25/32 - Phosphates of magnesium, calcium, strontium, or barium
  • A61L 27/12 - Phosphorus-containing materials, e.g. apatite
  • A61F 2/02 - Prostheses implantable into the body
  • A61F 2/28 - Bones

27.

THREE-DIMENSIONAL MATRICES OF STRUCTURED POROUS MONETITE FOR TISSUE ENGINEERING AND BONE REGENERATION, AND METHOD OF PREPARATION THEREOF

      
Document Number 02729920
Status In Force
Filing Date 2009-07-08
Open to Public Date 2010-01-14
Grant Date 2013-11-19
Owner HISTOCELL, S.L. (Spain)
Inventor
  • Font Perez, Julio
  • Castro Feo, Maria Begona
  • Del Olmo Basterrechea, Maite
  • Garcia Vazquez, Maria Dolores
  • Rubio Retama, Jorge
  • Lopez Cabarcos, Enrique
  • Rueda Rodriguez, Carmen
  • Tamimi Marino, Faleh
  • Hamdan Ali Alkhraisat, Mohammad

Abstract



The present invention is comprised within tissue
engineering and, specifically, within bone regeneration. The
invention relates to a porous three-dimensional matrix of
monetite which is biocompatible, has structured porosity and
is predefined and reabsorbable, as well as to the method of
synthesis capable of producing said material and the
applications thereof. These matrices are a perfect base for
cell colonization and proliferation, allowing the application
thereof in tissue engineering and bone regeneration as a
result of their advantageous properties of biocompatibility,
reabsorption, osteoinduction, revascularization, etc.

IPC Classes  ?

  • A61F 2/02 - Prostheses implantable into the body
  • A61F 2/28 - Bones
  • A61L 27/12 - Phosphorus-containing materials, e.g. apatite
  • C01B 25/32 - Phosphates of magnesium, calcium, strontium, or barium

28.

THREE-DIMENSIONAL MATRICES OF STRUCTURED POROUS MONETITE FOR TISSUE ENGINEERING AND OSSEOUS REGENERATION, AND METHOD FOR THE PREPARATION THEREOF

      
Application Number ES2008000482
Publication Number 2010/004057
Status In Force
Filing Date 2008-07-08
Publication Date 2010-01-14
Owner HISTOCELL, S.L (Spain)
Inventor
  • Font Perez, Julio
  • Castro Feo, Maria, Begoña
  • Garcia Vazquez, Maria, Dolores
  • Olmo Basterrechea, Maite Del
  • Rubio Retama, Jorge
  • Lopez Cabarcos, Enrique
  • Rueda Rodriguez, Carmen
  • Tamimi Mariño, Faleh
  • Ali Alkhraisat, Mohammad, Hamdan

Abstract

The present invention is in the field of tissue engineering and, specifically, that of osseous regeneration. The invention relates to a porous three-dimensional matrix of biocompatible monetite, of defined porosity and biodegradable, and the method of synthesis capable of producing said material and applications thereof. These matrices constitute a perfect base for cell colonisation and proliferation permitting application thereof in tissue engineering and osseous regeneration by virtue of their advantageous properties of biocompatibility, reabsorption, osteoinduction, revascularisation, etc.

IPC Classes  ?

  • C01B 25/32 - Phosphates of magnesium, calcium, strontium, or barium
  • A61L 27/12 - Phosphorus-containing materials, e.g. apatite
  • A61F 2/02 - Prostheses implantable into the body
  • A61F 2/28 - Bones