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2024
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Invention
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Method of sequence-independent quantification of proteolytically unstable plasma lambda free ligh... |
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Invention
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Acoramidis analogs for stabilizing transthyretin and inhibiting transthyretin misfolding.
Provid... |
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|
Invention
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Transthyretin stabilizing compounds.
Provided herein are compounds having activity against TTR r... |
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2023
|
Invention
|
Linear heteroaryl diamide ire1/xbp1s activators. Provided herein are compounds that activate IRE1... |
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Invention
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Cyclic pyrazole diamide ire1/xbp1s activators. Provided herein are compounds that activate IRE1/X... |
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Invention
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Heteroaryl diamide ire1/xbp1s activators.
Provided herein are compounds that activate IRE1/XBP1s... |
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|
Invention
|
Spirocycle containing pyridone compounds.
Provided herein are compounds that stabilize immunoglo... |
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Invention
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Spirocycle containing pyridine compounds.
Provided herein are compounds that stabilize immunoglo... |
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Invention
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Spirocycle containing bicyclic heteroaryl compounds.
Provided herein are compounds that stabiliz... |
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Invention
|
Spirocycle containing pyridone compounds. Provided herein are compounds that stabilize immunoglob... |
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|
Invention
|
Spirocycle containing bicyclic heteroaryl compounds. Provided herein are compounds that stabilize... |
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|
Invention
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Spirocycle containing pyridine compounds. Provided herein are compounds that stabilize immunoglob... |
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Invention
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Spirocyclic imidazolidinones and imidazolidinediones for treatment of light chain amyloidosis.
P... |
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2022
|
Invention
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Benzo[d]oxazole carboxamide and carboxylate derivatives as inhibitors of transthyretin (ttr) aggr... |
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|
Invention
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Acoramidis (3-(3-(3,5-dimethyl-1h-pyrazol-4-yl)propoxy)-4-fluorobenzoic acid) derivatives for sta... |
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|
Invention
|
Heteroaryl diamide ire1/xbp1s activators. Provided herein are compounds that activate IRE1/XBP1s,... |
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|
Invention
|
Spirocyclic imidazolidinones and imidazolidinediones for treatment of light chain amyloidosis. Pr... |
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2021
|
Invention
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Compounds, compositions and methods for stabilizing transthyretin and inhibiting transthyretin mi... |
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2014
|
Invention
|
Transthyretin antibodies and uses thereof. The present invention provides compositions comprising... |
