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2025
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Invention
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Methods and compositions for treating a proprotein convertase subtilisin kexin (pcsk9) gene-assoc... |
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Invention
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Irna compositions and methods for silencing growth factor receptor bound protein 14 (grb14) in th... |
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Invention
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Universal non-targeting sirna compositions and methods of use thereof.
The present invention pro... |
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Invention
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Modified rna agents with reduced off-target effect.
One aspect of the present invention relates ... |
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Invention
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Reversir tm compounds.
The present invention relates, in general to agents that modulate the pha... |
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2024
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Invention
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Multi-targeted single entity conjugates.
The present invention relates, in general to, compounds... |
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Invention
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Ketohexokinase (khk) irna compositions and methods of use thereof.
The present invention relates... |
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Invention
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Snca-targeting sirna compositions for treating snca-associated disease.
The disclosure relates t... |
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Invention
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Methods and compositions for treating transthyretin (ttr)- associated diseases. The invention rel... |
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Invention
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Methods and compositions for treating an angiotensinogen- (agt-) associated disorder. e.ge.ge.g.,... |
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Invention
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Methods and compositions for treating ketohexokinase (khk)-associated diseases. The disclosure re... |
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Invention
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Compositions and methods for inhibiting expression of the pcsk9 gene.
The invention relates to a... |
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Invention
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Cell death-inducing dffa-like effector b (cideb) irna compositions and methods of use thereof. Th... |
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Invention
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Compositions and methods for improving strand biased.
One aspect of the present invention relate... |
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Invention
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Serum amyloid p component (apcs) irna compositions and methods of use thereof.
The invention rel... |
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Invention
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Peritoneal macrophages comprising a nanoparticle encapsulating a nucleic acid molecule and method... |
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Invention
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Activin a receptor type 1c (acvr1c) irna compositions and methods of use thereof. The present dis... |
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Invention
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Compositions and methods for silencing carbonic anhydrase 2 expression.
The disclosure relates t... |
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Invention
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Xanthine dehydrogenase (xdh) irna compositions and methods of use thereof.
The present invention... |
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P/S
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Providing scientific information in the field of biopharmaceuticals. |
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P/S
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Providing scientific information in the field of
biopharmaceuticals. |
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Invention
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Polynucleotide agents targeting complement component c5 and methods of use thereof.
The inventio... |
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Invention
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Aminoadipate-semialdehyde synthase (aass) irna compositions and methods of use thereof. The inven... |
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Invention
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Methods and compositions for treating ctnnb1-associated disorders. The present invention relates ... |
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Invention
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Angiotensinogen (agt) irna compositions and methods of use thereof.
The present invention relate... |
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Invention
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Heparin sulfate biosynthesis pathway enzyme irna agent compositions and methods of use thereof.
... |
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Invention
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High mobility group box-1 (hmgb1) irna compositions and methods of use thereof.
RNAi agents, e.g... |
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P/S
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Biochemical testing for scientific research purposes. Medical testing for diagnostic or treatment... |
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P/S
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Scientific research; scientific research in the fields of pharmaceuticals and medicine, chemical ... |
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P/S
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Scientific research; scientific research in the fields of
pharmaceuticals and medicine, chemical... |
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Invention
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Complement component c5 irna compositions and methods of use.
The invention relates to iRNA, e.g... |
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P/S
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Scientific research for others in the field of pharmaceutical drug discovery and development; ite... |
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P/S
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Genetic testing for scientific research purposes. Genetic testing for medical purposes. |
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P/S
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Scientific research; scientific research in the fields of pharmaceuticals and medicine; chemical ... |
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P/S
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DNA screening for scientific research purposes; DNA screening for forensic research purposes; DNA... |
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Invention
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Transthyretin (ttr) irna compositions and methods of use thereof for treating or preventing ttr-a... |
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Invention
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Tunable reversir tm compounds.
The present invention relates, in general to agents that modulate... |
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Invention
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Apolipoprotein c3 (apoc3) irna compositions and methods of use thereof.
The present invention re... |
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Invention
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Serpina1 irna compositions and methods of use thereof.
The invention relates to RNAi agents, e.g... |
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P/S
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Providing scientific information in the field of biopharmaceuticals |
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Invention
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Compositions and methods for inhibiting expression of the alas1 gene.
The invention relates to d... |
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Invention
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Inhibin subunit beta e (inhbe) modulator compositions and methods of use thereof.
The present in... |
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Invention
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Compositions and methods for inhibition of hao1 (hydroxyacid oxidase 1 (glycolate oxidase)) gene ... |
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Invention
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Oligonucleotide-ligand conjugates and process for their preparation.
The present invention relat... |
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Invention
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3-hydroxy-3-methylglutaryl-coa reductase (hmgcr) irna compositions and methods of use thereof.
T... |
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2023
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Invention
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Single-stranded loop oligonucleotides.
One aspect of the present invention relates to a single-s... |
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P/S
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Advertising services to promote public awareness of medical
conditions; advertising services to ... |
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Invention
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Actin-binding lim protein 3 (ablim3) irna agent compositions and methods of use thereof.
The dis... |
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P/S
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Advertising services to promote public awareness of medical conditions; advertising services to p... |
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Invention
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Microtubule associated protein tau (mapt) irna agent compositions and methods of use thereof.
Th... |
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2022
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Invention
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Irna compositions and methods for silencing mylip.
The invention relates to double-stranded ribo... |
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Invention
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Oligonucleotides with 2'-deoxy-2'-f-2'-c-methyl nucleotides.
The present disclosure relates gene... |
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Invention
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Irna compositions and methods for silencing angptl4.
The invention relates to double-stranded ri... |
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Invention
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Peptide ligands for cns and ocular delivery of rnai compounds.
The disclosure relates to RNA age... |
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Invention
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Multiplexing targeting ligands through click chemistry at the anomeric site of sugars.
The prese... |
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Invention
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Aminooxy click chemistry (aocc): a versatile conjugation approach.
The present disclosure relate... |
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Invention
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Bis-rnai compounds for cns delivery.
One aspect of the invention relates to molecules that targe... |
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P/S
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Providing information on financial assistance programs for the access of pharmaceutical treatment... |
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2021
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P/S
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Pharmaceuticals having a particularly long duration of
effect as compared to others of the same ... |
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Invention
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Modified double stranded oligonucleotides.
One aspect of the present invention relates to double... |
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P/S
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Advertising services to promote public awareness about porphyria among affected individuals and t... |
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P/S
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Promoting public awareness about porphyria among affected individuals and their families Educatio... |
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P/S
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Advertising services to promote public awareness about
porphyria among affected individuals and ... |
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P/S
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Pharmaceutical preparations for the treatment of amyloidosis. |
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P/S
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Pharmaceutical preparations for the treatment of
amyloidosis. |
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P/S
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Pharmaceutical preparations. |
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P/S
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Pharmaceutical preparations for the treatment of amyloidosis |
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P/S
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Promoting public awareness about primary hyperoxaluria among affected individuals and their famil... |
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P/S
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Maintaining a clinical registry database for patients with inherited disorders of the liver and p... |
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P/S
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Promoting public awareness about hATTR amyloidosis among affected individuals and their families. |
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2020
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Invention
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Synthesis of 3 -rna oligonucleotides.
The disclosure is directed to monomers and methods for syn... |
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P/S
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Pharmaceutical preparations for the treatment of amyloidosis. |
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P/S
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Pharmaceutical preparations for the treatment of primary hyperoxaluria. |
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P/S
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Pharmaceutical preparations for the treatment of transthyretin-mediated amyloidosis; pharmaceutic... |
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P/S
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Pharmaceutical preparations for the treatment of porphyria. |
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P/S
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Pharmaceutical preparations for the treatment of transthyretin-mediated amyloidosis; Pharmaceutic... |
