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2025
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Invention
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Inhibitors of malt1 and methods of their use. Methods for treating a B-cell malignancy in a human... |
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Invention
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Formulations, crystalline forms and dosage regimens of a malt1 inhibitor. The present invention r... |
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2024
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Invention
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(r) -n-ethyl-5-fluoro-n-isopropyl-2- ( (5- (2- (6- ( (2-methoxyethyl) (methyl) amino) -2-methylhe... |
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2023
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Invention
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Malt1 inhibitors. Disclosed are compounds, compositions and methods for treating of diseases, syn... |
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Invention
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Crystalline forms of a2a receptor antagonist, preparation methods, and uses thereof. Disclosed ar... |
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Invention
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Pharmaceutical compositions of an a2a receptor antagonist. Disclosed is pharmaceutical compositio... |
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Invention
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A crystal form of a fused heterocycle derivative compound. Provided herein are a fused heterocycl... |
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Invention
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Cyclobutyl substituted bicyclic compounds. The present invention relates to pharmaceutical agents... |
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Invention
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Substituted 1-phenyl-3, 4-dihydropyrido [3, 4-d] pyrimidin-2-one derivatives. The present inventi... |
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Invention
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Combinations comprising a menin-mll inhibitor and at least one other therapeutic agent. Disclosed... |
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Invention
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Combinations comprising a menin-mll inhibitor and a bcl-2 inhibitor. Disclosed are combinations c... |
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Invention
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Crystalline forms of an inhibitor of the menin/mll interaction. The present invention relates to ... |
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2022
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Invention
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Processes for the preparation of (s)-2-(4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl... |
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Invention
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(r)-n-ethyl-5-fluoro-n-isopropyl-2-((5-(2-(6-((2-methoxyethyl)(methyl)amino)-2-methylhexan-3-yl)-... |
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Invention
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Dihydropyrimidine derivatives and uses thereof in the treatment of hbv infection or of hbv-induce... |
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Invention
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Pyridazines or 1,2,4-triazines substituted by spirocyclic amines. The present invention relates t... |
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Invention
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Fused heterocyclic derivatives. The application describes fused heterocycle derivative compounds,... |
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Invention
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Substituted phenyl-1h-pyrrolo[2, 3-c]pyridine derivatives. The present invention relates to pharm... |
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Invention
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Combination therapies. Disclosed are combinations comprising a therapeutically effective amount o... |
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Invention
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Substituted spiro derivatives. The present invention relates to pharmaceutical agents useful for ... |
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2021
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Invention
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Fused heterocyclic derivatives and their use in the treatment of hbv infection. The application d... |
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Invention
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Fused heterocyclic derivatives as hbv inhibitors. The application describes fused heterocycle der... |
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Invention
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Pharmaceutical formulation. The invention relates to pharmaceutical formulations comprising an ac... |
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Invention
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Solid formulation. The invention relates to pharmaceutical formulations comprising an active phar... |
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Invention
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Combination therapy for treating hepatitis b virus infection. Provided are RNA interference (RNAi... |
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Invention
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Fused ring pyrimidone derivatives for use in the treatment of hbv infection or of hbv-induced dis... |
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Invention
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Pharmaceutical formulations comprising a malt1 inhibitor and a mixture of polyethylene glycol wit... |
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Invention
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Triggering method and triggering apparatus of intervention prompt on the basis of user smoking be... |
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2020
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Invention
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Heteroaryldihydropyrimidine derivatives and methods of treating hepatitis b infections. Provided ... |
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Invention
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Substituted straight chain spiro derivatives. Provided herein are pharmaceutical agents useful fo... |
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Invention
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Pharmaceutical formulation. Pharmaceutical formulations comprising an active pharmaceutical ingre... |
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Invention
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Solid formulation. Provided are pharmaceutical formulations comprising an active pharmaceutical i... |
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Invention
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Synthesis of 3-nitro-n-(2,2,2-trifluoroethyl)-4-pyridinamine. The present invention relates to a ... |
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Invention
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H-imidazo[4,5-c]pyridin-2-one. HHH-imidazo[4,5-c]pyridin-2-one, and to new compounds used as inte... |
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Invention
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Compounds and methods for the targeted degradation of interleukin-1 receptor-associated kinase 1 ... |
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Invention
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H-pyrazole-4-carboxamide monohydrate. NHH-pyrazole-4-carboxamide (Compound A) monohydrate and pro... |
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Invention
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Pharmaceutical formulations. The invention relates to pharmaceutical formulations comprising an a... |
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2019
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Invention
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Thienopyridinone compounds. New thienopyridinone compounds, pharmaceutical compositions comprisin... |
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2018
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Invention
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Processes for preparing compounds/intermediates useful in the treatment of viral infections. An i... |