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2024
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Invention
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Bispecific chimeric antigen receptors and encoding polynucleotides, vectors and cells thereof. Th... |
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Invention
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Vivo gene therapy using intraosseous delivery of a lentiviralgene construct. Methods, composition... |
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Invention
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Bispecific or-gate chimeric antigen receptor responsive to cd20 and cd19. A CD20-OR-CD19 chimeric... |
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2023
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Invention
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Detection and treatment of autoimmune disorders.
Disclosed herein are methods of treatment of au... |
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Invention
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Methods of use for car t cells. The present disclosure relates to methods of treating a patient w... |
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Invention
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Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20. A CD19-OR-CD20 chimeric... |
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Invention
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Methods of exogenous drug activation of chemical-induced signaling complexes expressed in enginee... |
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Invention
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Homology directed repair compositions for the treatment of hemoglobinopathies. The present disclo... |
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Invention
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Early intervention methods to prevent or ameliorate toxicity. Provided are methods for preventing... |
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Invention
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Bispecific chimeric antigen receptors, encoding polynucleotides and use of receptors thereof to t... |
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Invention
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Vaccine for falciparum malaria. The invention provides compositions and methods for preventing or... |
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2022
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Invention
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Transgene genetic tags and methods of use. Embodiments of the disclosure include methods of manuf... |
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Invention
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Monocyte and macrophage binding aptamers and their application. Provided herein are compositions ... |
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Invention
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Methods of treating kawasaki disease. The present invention relates to the discovery that etanerc... |
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2021
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Invention
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Drug regulated transgene expression. The present invention provides nucleic acids, vectors, host ... |
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Invention
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Disinfection method and apparatus. Photosensitizers are incorporated into articles, such a person... |
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Invention
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Antimicrobial preventive netting. An antimicrobial preventive netting is disclosed that includes ... |
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Invention
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Vaccine generation. An apparatus for vaccine generation includes a syringe with a cavity that inc... |
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Invention
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Proteomic screening for lysosomal storage diseases. Early detection of lysosomal storage diseases... |
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Invention
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Doubly attenuated late liver stage malaria parasites and related compositions and methods. The di... |
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2020
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Invention
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Production of engineered t-cells by sleeping beauty transposon coupled with methotrexate selectio... |
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Invention
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Bispecific car t-cells for solid tumor targeting. Disclosed herein are methods of engineering a b... |
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Invention
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Bispecific chimeric antigen receptors, encoding polynucleotides thereof and methods of use thereo... |
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Invention
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Transgene genetic tags and methods of use. The present invention provides genetic tags operably l... |
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2019
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Invention
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Genetic engineering of macrophages for immunotherapy. Disclosed are methods of making a genetical... |
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Invention
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Newborn screening for primary immunodeficiencies, cystinosis, and wilson disease. Newborn screeni... |
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Invention
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Artificial expression constructs for selectively modulating gene expression in interneurons. Arti... |
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Invention
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Methods and compositions comprising b7h3 chimeric antigen receptors. Embodiments of the methods a... |
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Invention
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Detection and treatment of autoimmune disorders. Disclosed herein are methods of treatment of aut... |
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Invention
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Rapamycin resistant cells. The present application relates to, inter alia, compositions including... |
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Invention
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Expression of foxp3 in edited cd34+ cells. + cells. In some embodiments, guide RNA sequences that... |
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Invention
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Rescuing voltage-gated sodium channel function in inhibitory neurons. Selectively providing volta... |
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Invention
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Sequencing method for car t cell therapy. The present disclosure relates to methods of treating a... |
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Invention
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Closed-system manufacturing process for car-t cells. Some embodiments provided herein relate to m... |
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Invention
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Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors. Aspe... |
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2018
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Invention
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Generating mammalian t cell activation inducible synthetic promoters (syn+pro) to improve t cell ... |
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Invention
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Therapeutic genome editing in wiskott-aldrich syndrome and x-linked thrombocytopenia. Described h... |
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Invention
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Plasmodium sporozoite npdp peptides as vaccine and target novel malaria vaccines and antibodies b... |
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Invention
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Phospholipid ether (ple) car t cell tumor targeting (ctct) agents. Aspects of the invention descr... |
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2017
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Invention
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Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of tra... |
