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2025
|
Invention
|
N-biaryl sulfonamides as modulators of the hippo pathway. Provided are compounds of Formula I: an... |
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2022
|
Invention
|
Tricyclic sultams and sulfamides as antitumor agents.
Compounds of formula I, that modulate DCAF... |
|
|
Invention
|
Tricyclic sultams and sulfamides as antitumor agents. Compounds of formula I, that modulate DCAF1... |
|
|
Invention
|
Aryl ethers and uses thereof. The present disclosure relates to HIF-2α inhibitors and methods of ... |
|
2021
|
Invention
|
Cd73 inhibitors and uses thereof. The present disclosure provides compounds of Formula (II)
... |
|
2020
|
Invention
|
Methods of preparing substituted indanes.
This application discloses methods for the synthesis o... |
|
|
Invention
|
Pyrazolesulfonamides as antitumor agents.
Compounds of formula I, that induce RBM39 protein degr... |
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|
Invention
|
Pyrazolesulfonamides as antitumor agents. Compounds of formula I, that induce RBM39 protein degra... |
|
|
Invention
|
Aryl ethers and uses thereof.
The present disclosure relates to HIF-2α inhibitors and methods of... |
|
2019
|
Invention
|
Solid dispersions and pharmaceutical compositions comprising a substituted indane and methods for... |
|
|
Invention
|
Compositions and methods for inhibiting cd73. Compounds that modulate CD73 activity, pharmaceutic... |
|
|
Invention
|
Combination therapy of a hif-2-α inhibitor and an immunotherapeutic agent and uses thereof. The p... |
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|
Invention
|
Methods of reducing inflammation of the digestive system with inhibitors of hif-2- alpha.
The pr... |
|
|
Invention
|
Methods of reducing inflammation of the digestive system with inhibitors of hif-2-alpha. The pres... |
|
2018
|
Invention
|
Compositions for use in treating pulmonary arterial hypertension.
The present disclosure provide... |
|
|
Invention
|
Cd73 inhibitors and uses thereof.
Compounds that modulate CD73 activity, pharmaceutical composit... |
|
|
Invention
|
Cd73 inhibitors and uses thereof. Compounds that modulate CD73 activity, pharmaceutical compositi... |
|
2016
|
Invention
|
Tricyclic inhibitors of hif-2-alpha and uses thereof. Compounds comprising a fused tricylic core ... |
|
|
Invention
|
Combination therapy of a hif-2-alpha inhibitor and an immunotherapeutic agent and uses thereof. T... |
|
|
Invention
|
Hif-2-alpha inhibitor polymorphs.
Chemical compounds that modulate HIF-2α activity, their polymo... |
|
|
Invention
|
Hif-2-alpha inhibitor polymorphs. Chemical compounds that modulate HIF-2α activity, their polymor... |
|
|
Invention
|
Compositions for use in treating pulmonary arterial hypertension. The present disclosure provides... |
|
|
Invention
|
Compositions for use in treating glioblastoma. The present disclosure provides methods of treatin... |
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|
Invention
|
Aromatic compounds and uses thereof. Disclosed herein are substituted indane derivatives useful a... |
|
|
Invention
|
Substituted pyridines and uses thereof. Substituted pyridines that modulate HIF-2a activity, phar... |
|
|
Invention
|
Aromatic compounds and uses thereof. Aromatic entities that modulate HIF-2α activity, pharmaceuti... |
|
2015
|
Invention
|
Benzimidazole derivatives and uses thereof. Benzimidazole derivatives of Formula I, that modulate... |
|
2014
|
Invention
|
Cyclic sulfone and sulfoximine analogs and uses thereof. The present disclosure relates to cyclic... |
