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Type PI
        Brevet 90
        Marque 26
Juridiction
        États-Unis 75
        International 35
        Europe 4
        Canada 2
Date
2025 mai 2
2025 (AACJ) 4
2024 1
2023 2
2022 7
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Classe IPC
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules 63
A61N 5/00 - Thérapie par radiations 21
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures 9
A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00) 7
A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores 7
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Classe NICE
10 - Appareils et instruments médicaux 23
09 - Appareils et instruments scientifiques et électriques 8
41 - Éducation, divertissements, activités sportives et culturelles 5
42 - Services scientifiques, technologiques et industriels, recherche et conception 5
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture. 5
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Statut
En Instance 6
Enregistré / En vigueur 110
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1.

Brachytherapy applicator

      
Numéro d'application 29867871
Numéro de brevet D1077230
Statut Délivré - en vigueur
Date de dépôt 2022-11-11
Date de la première publication 2025-05-27
Date d'octroi 2025-05-27
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Van Manen, Jan Willem

2.

Brachytherapy applicator

      
Numéro d'application 29867869
Numéro de brevet D1077229
Statut Délivré - en vigueur
Date de dépôt 2022-11-11
Date de la première publication 2025-05-27
Date d'octroi 2025-05-27
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Van Manen, Jan Willem

3.

MARKING ARRANGEMENT, MEDICAL DEVICE, AND SYSTEM FOR RECONSTRUCTING A PLANNED TRAJECTORY

      
Numéro d'application 18720070
Statut En instance
Date de dépôt 2022-12-16
Date de la première publication 2025-02-13
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Lie-Kwie-Sjoe, Farahnaz

Abrégé

The invention relates to a marking arrangement (10) for marking positions of a medical device along a source trajectory (200), comprising a plurality of markers arranged in series along the source trajectory. Each marker (100) is aligned with the source trajectory and made of a first material and comprises a coating (110), wherein the coating is made of a second material disposed on a surface of the marker. A thickness (T) of the coating is smaller than 1 micrometer, and an interdistance (S) between each marker is smaller than 3 millimeter. The invention further relates to a system for reconstructing a planned trajectory of a medical device, comprising a detection module arranged for detecting the marking arrangement (10) and a treatment calculation module arranged for determining trajectories and dwell times.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
  • A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

4.

BRACHYTHERAPY SENSOR CABLE

      
Numéro d'application 18705893
Statut En instance
Date de dépôt 2022-11-02
Date de la première publication 2025-01-09
Propriétaire NUCLETRON OPERTIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van De Wardt, Cor
  • De Vries, Frits Pieter
  • Henning, Johan

Abrégé

According to one aspect, a brachytherapy sensor cable is provided which can be moved through a lumen towards an applicator positioned in a human body and wherein a distal part of the sensor cable comprises a sensor; wherein a hollow passage is formed between the proximal part and the distal part to guide signal wiring of the sensor through the hollow conduit of distal part and proximal part towards a connector that is connectable to the afterloader system.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

5.

MODULAR BRACHYTHERAPY APPLICATOR

      
Numéro d'application 18644790
Statut En instance
Date de dépôt 2024-04-24
Date de la première publication 2024-08-22
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van Manen, Jan Willem
  • Arikan, Eylem
  • Van Erp, Wilko

Abrégé

Embodiments of the disclosure may be drawn to brachytherapy applicators. Exemplary applicators may include an interstitial tube having a body with a proximal end and a distal end and a central conduit extending from the distal end of the body, wherein the central conduit includes a proximal opening, a distal opening, and a channel extending from the proximal opening to the distal opening, and wherein the proximal opening is offset from an axis of the body. The proximal opening may be configured to fluidly connect to a brachytherapy guide tube, and the channel of the central conduit may be dimensioned to receive at least one of a needle or a catheter therethrough.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

6.

MARKING ARRANGEMENT, MEDICAL DEVICE, AND SYSTEM FOR RECONSTRUCTING A PLANNED TRAJECTORY

      
Numéro d'application NL2022050727
Numéro de publication 2023/113602
Statut Délivré - en vigueur
Date de dépôt 2022-12-16
Date de publication 2023-06-22
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Lie-Kwie-Sjoe, Farahnaz

Abrégé

The invention relates to a marking arrangement (10) for marking positions of a medical device along a source trajectory (200), comprising a plurality of markers arranged in series along the source trajectory. Each marker (100) is aligned with the source trajectory and made of a first material and comprises a coating (110), wherein the coating is made of a second material disposed on a surface of the marker. A thickness (T) of the coating is smaller than 1 micrometer, and an interdistance (S) between each marker is smaller than 3 millimeter. The invention further relates to a system for reconstructing a planned trajectory of a medical device, comprising a detection module arranged for detecting the marking arrangement (10) and a treatment calculation module arranged for determining trajectories and dwell times.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

7.

BRACHYTHERAPY SENSOR CABLE

      
Numéro d'application NL2022050617
Numéro de publication 2023/080781
Statut Délivré - en vigueur
Date de dépôt 2022-11-02
Date de publication 2023-05-11
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van De Wardt, Cor
  • De Vries, Frits Pieter
  • Henning, Johan

Abrégé

According to one aspect, a brachytherapy sensor cable is provided which can be moved through a lumen towards an applicator positioned in a human body and wherein a distal part of the sensor cable comprises a sensor; wherein a hollow passage is formed between the proximal part and the distal part to guide signal wiring of the sensor through the hollow conduit of distal part and proximal part towards a connector that is connectable to the afterloader system.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

8.

SELECTOR FOR REMOTELY MEDICAL DEVICE / AFTERLOADING

      
Numéro d'application 17754089
Statut En instance
Date de dépôt 2020-09-30
Date de la première publication 2022-11-24
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • De Vries, Frits Pieter
  • Schouten, Luuk
  • Welgraven, Aalt Jacob

Abrégé

The invention relates to a medical device for transporting and positioning a therapeutic emitting element into a treatment channel to be temporarily placed in or at the body of the patient to treat tumours. The therapeutic emitting element is connected to a transport element and which is driven by at least one drive motor. The device has a connecting element comprising multiple connector openings. The connecting element is used for connecting a transport tube to a respective connector opening. The transport tube is connected to an applicator, needle, tube or catheter for driving the transport element into the treatment channel. The device has a selector mechanism through which the plurality of transport elements are driven. An annular guiding arrangement guides the transport elements into connector openings in the connecting element. The annular guiding arrangement also comprises a plurality of spaced outlets. The inlets of the multiple patterns are each connected to an outlet by guiding channels. Each outlet aligns to a connector opening in the connecting element to allow the transport element from each outlet to be driven into the connector openings.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

9.

Pair of left and right brachytherapy ovoids

      
Numéro d'application 29790307
Numéro de brevet D0966521
Statut Délivré - en vigueur
Date de dépôt 2021-11-18
Date de la première publication 2022-10-11
Date d'octroi 2022-10-11
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s) Van Manen, Jan Willem

10.

MARKER FOR MEDICAL IMAGING

      
Numéro d'application 17596989
Statut En instance
Date de dépôt 2020-06-25
Date de la première publication 2022-09-29
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Schuurman, Jeroen Anton
  • De Jager, Wim
  • Van Den Berg, Martin
  • Henning, Johan

Abrégé

Embodiments of the disclosure may be drawn to brachytherapy markers. Exemplary markers may include an inner ring consisting of one or more of copper, brass, gold, silver, or titanium; an outer coating consisting of one or more of nickel or iron oxide, wherein a thickness of the outer coating may be about 1 μm to about 30 μm; and a central opening, wherein a diameter of the central opening may be about 0.50 mm to about 3.00 mm.

Classes IPC  ?

  • A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

11.

Sensing apparatus

      
Numéro d'application 17632080
Numéro de brevet 12296194
Statut Délivré - en vigueur
Date de dépôt 2020-08-03
Date de la première publication 2022-09-01
Date d'octroi 2025-05-13
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Ferwerda, Sjoerd
  • Van Beek, Martin

Abrégé

A sensing apparatus for sensing the presence of a radioactive source, or check-dummy- or sensor cable, at a point along the sensing apparatus during a brachytherapy procedure. The sensing apparatus comprises a transfer tube comprising a first end and a second end. The second end being downstream of the first end. The sensing apparatus further comprises sensing means operable to detect the presence of a radioactive source, or check-dummy- or sensor cable, at a point downstream of the first end of the transfer tube. The reason for the plurality of “prisms” or the semispheres, is that they are orientation independent to the light fibers, simplifying assembly. Alternatively the plurality of prisms may be substituted by two half-spherical “prisms”. Between the prisms, a light blocking surface need to be placed to avoid optical short circuits.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

12.

BRACHYTHERAPY SOURCE ASSEMBLY

      
Numéro d'application 17596987
Statut En instance
Date de dépôt 2020-06-25
Date de la première publication 2022-07-28
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Schuurman, Jeroen Anton
  • De Vries, Frits Pieter
  • De Jager, Wim

Abrégé

Embodiments of the disclosure may be drawn to brachytherapy source assemblies. Exemplary source assemblies may include a cable made of an electrically non-conductive material and a guide wire coupled to and extending from a distal end of the cable. The guide wire may have a distal end region and a proximal end region, and the guide wire may have a length that is shorter than a length of the cable. The assembly may also include a capsule located at a distal end region of the guide wire, and the capsule may include a chamber configured to contain a radioactive source. The capsule may be formed of a non-ferromagnetic material and may have a ferromagnetic coating that at least partially covers the capsule.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

13.

Pair of left and right brachytherapy ovoids

      
Numéro d'application 29725844
Numéro de brevet D0954956
Statut Délivré - en vigueur
Date de dépôt 2020-02-27
Date de la première publication 2022-06-14
Date d'octroi 2022-06-14
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s) Van Manen, Jan Willem

14.

Modular brachytherapy applicator

      
Numéro d'application 17593760
Numéro de brevet 11992701
Statut Délivré - en vigueur
Date de dépôt 2020-02-27
Date de la première publication 2022-05-26
Date d'octroi 2024-05-28
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Van Manen, Jan Willem
  • Arikan, Eylem
  • Van Erp, Wilko

Abrégé

Exemplary brachytherapy applicators may include an interstitial tube having a body with a proximal end and a distal end and a central conduit extending from the distal end of the body, wherein the central conduit includes a proximal opening, a distal opening, and a channel extending from the proximal opening to the distal opening, and wherein the proximal opening is offset from an axis of the body. The proximal opening may be configured to fluidly connect to a brachytherapy guide tube, and the channel of the central conduit may be dimensioned to receive at least one of a needle or a catheter therethrough.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

15.

Brachytherapy applicator

      
Numéro d'application 29725824
Numéro de brevet D0939706
Statut Délivré - en vigueur
Date de dépôt 2020-02-27
Date de la première publication 2021-12-28
Date d'octroi 2021-12-28
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s) Van Manen, Jan Willem

16.

SELECTOR FOR REMOTELY MEDICAL DEVICE / AFTERLOADING

      
Numéro d'application NL2020050604
Numéro de publication 2021/066648
Statut Délivré - en vigueur
Date de dépôt 2020-09-30
Date de publication 2021-04-08
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • De Vries, Frits Pieter
  • Schouten, Luuk
  • Welgraven, Aalt Jacob

Abrégé

The invention relates to a medical device for transporting and positioning a therapeutic emitting element into a treatment channel to be temporarily placed in or at the body of the patient to treat tumours. The therapeutic emitting element is connected to a transport element and which is driven by at least one drive motor. The device has a connecting element comprising multiple connector openings. The connecting element is used for connecting a transport tube to a respective connector opening. The transport tube is connected to an applicator, needle, tube or catheter for driving the transport element into the treatment channel. The device has a selector mechanism through which the plurality of transport elements are driven. An annular guiding arrangement guides the transport elements into connector openings in the connecting element. The annular guiding arrangement also comprises a plurality of spaced outlets. The inlets of the multiple patterns are each connected to an outlet by guiding channels. Each outlet aligns to a connector opening in the connecting element to allow the transport element from each outlet to be driven into the connector openings.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

17.

A SENSING APPARATUS

      
Numéro d'application NL2020050493
Numéro de publication 2021/025553
Statut Délivré - en vigueur
Date de dépôt 2020-08-03
Date de publication 2021-02-11
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Ferwerda, Sjoerd
  • Van Beek, Martin

Abrégé

A sensing apparatus for sensing the presence of a radioactive source, or check- dummy- or sensor cable, at a point along the sensing apparatus during a brachytherapy procedure. The sensing apparatus comprises a transfer tube comprising a first end and a second end. The second end being downstream of the first end. The sensing apparatus further comprises sensing means operable to detect the presence of a radioactive source, or check- dummy- or sensor cable, at a point downstream of the first end of the transfer tube. The reason for the plurality of "prisms" or the semispheres, is that they are orientation independent to the light fibers, simplifying assembly. Alternatively the pluraliy of prisms may be substituted by two half-spherical "prisms". Between the prisms, a light blocking surface need to be placed to avoid optical short circuits.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

18.

BRACHYTHERAPY SOURCE ASSEMBLY

      
Numéro d'application NL2020050416
Numéro de publication 2020/263091
Statut Délivré - en vigueur
Date de dépôt 2020-06-25
Date de publication 2020-12-30
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Schuurman, Jeroen Anton
  • De Vries, Frits Pieter
  • De Jager, Wim

Abrégé

Embodiments of the disclosure may be drawn to brachytherapy source assemblies. Exemplary source assemblies may include a cable made of an electrically non-conductive material and a guide wire coupled to and extending from a distal end of the cable. The guide wire may have a distal end region and a proximal end region, and the guide wire may have a length that is shorter than a length of the cable. The assembly may also include a capsule located at a distal end region of the guide wire, and the capsule may include a chamber configured to contain a radioactive source. The capsule may be formed of a non-ferromagnetic material and may have a ferromagnetic coating that at least partially covers the capsule.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

19.

MARKER FOR MEDICAL IMAGING

      
Numéro d'application NL2020050417
Numéro de publication 2020/263092
Statut Délivré - en vigueur
Date de dépôt 2020-06-25
Date de publication 2020-12-30
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Schuurman, Jeroen Anton
  • De Jager, Wim
  • Van Den Berg, Martin
  • Henning, Johan

Abrégé

Embodiments of the disclosure may be drawn to brachytherapy markers. Exemplary markers may include an inner ring consisting of one or more of copper, brass, gold, silver, or titanium; an outer coating consisting of one or more of nickel or iron oxide, wherein a thickness of the outer coating may be about 1 μm to about 30 μm; and a central opening, wherein a diameter of the central opening may be about 0.50 mm to about 3.00 mm.

Classes IPC  ?

  • A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

20.

MODULAR BRACHYTHERAPY APPLICATOR

      
Numéro d'application NL2020050128
Numéro de publication 2020/197379
Statut Délivré - en vigueur
Date de dépôt 2020-02-27
Date de publication 2020-10-01
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van Manen, Jan Willem
  • Arikan, Eylem
  • Van Erp, Wilko

Abrégé

Embodiments of the disclosure may be drawn to brachytherapy applicators. Exemplary applicators may include an interstitial tube having a body with a proximal end and a distal end and a central conduit extending from the distal end of the body, wherein the central conduit includes a proximal opening, a distal opening, and a channel extending from the proximal opening to the distal opening, and wherein the proximal opening is offset from an axis of the body. The proximal opening may be configured to fluidly connect to a brachytherapy guide tube, and the channel of the central conduit may be dimensioned to receive at least one of a needle or a catheter there through.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

21.

Wireless afterloader

      
Numéro d'application 16223592
Numéro de brevet 11383099
Statut Délivré - en vigueur
Date de dépôt 2018-12-18
Date de la première publication 2020-06-18
Date d'octroi 2022-07-12
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Van De Wardt, Cor
  • Henning, Johan

Abrégé

Embodiments of the disclosure may be drawn to wireless afterloaders. Exemplary afterloaders may include a central processing unit, a first complex programmable logic device having a memory, a transceiver operably connected to the complex programmable logic device, wherein the transceiver is configured to wirelessly receive data from a second complex programmable logic device separate from the wireless afterloader, and a battery.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
  • A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
  • A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci

22.

Brachytherapy applicators having ultrasound elements

      
Numéro d'application 15564960
Numéro de brevet 10668299
Statut Délivré - en vigueur
Date de dépôt 2016-04-11
Date de la première publication 2018-03-15
Date d'octroi 2020-06-02
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Krechting, Paulus Cornelis Hendrikus Maria
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • De Becker, Jan F. L.
  • Welberg, Anton J. G.

Abrégé

A brachytherapy system includes a brachytherapy applicator. The brachytherapy applicator includes an applicator tube and a radiation source configured to deliver radiation to a tumor. At least a portion of the applicator tube is configured to conform to at least a portion of a patient's anatomy. At least one ultrasound element or probe is coupled to or embedded with the applicator tube.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 8/08 - Applications cliniques
  • A61B 8/12 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores dans des cavités ou des conduits du corps, p. ex. en utilisant des cathéters
  • A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
  • A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

23.

Advanced applicator systems and methods

      
Numéro d'application 15532050
Numéro de brevet 10596390
Statut Délivré - en vigueur
Date de dépôt 2015-12-04
Date de la première publication 2017-10-12
Date d'octroi 2020-03-24
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Steller, Hendrik
  • Van Erp, Wilhelmus
  • Van Manen, Jan Willem
  • Geheniau, Norbert Johan Lukas

Abrégé

Systems, methods, and apparatuses are provided for an advanced gynecological applicator. In accordance with some embodiments, a brachytherapy applicator head and assembly is provided. The assembly may include two ovoid tubes configured to receive radiation sources, the two ovoid tubes combining to form a rounded applicator having a middle opening and comprising a plurality of needle holes to guide interstitial needles. The assembly may also include a central applicator tube configured to receive a radiation source that is located within the middle opening. Additionally, the assembly may include a vaginal cap that includes a tool-free connection to the two ovoid tubes and includes needle guides that align with the needle holes of the two ovoid tubes. The assembly may include a one-piece template for securing interstitial needles. The assembly may further include a tool-free connector to secure the two ovoid tubes to the central applicator tube.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 1/303 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour le vagin, c.-à-d. vaginoscopes
  • A61B 17/02 - Instruments, dispositifs ou procédés chirurgicaux pour maintenir les blessures ouvertes, p. ex. rétracteursÉcarteurs

24.

Methods and systems for brachytherapy planning based on imaging data

      
Numéro d'application 15312978
Numéro de brevet 10758745
Statut Délivré - en vigueur
Date de dépôt 2015-05-28
Date de la première publication 2017-05-04
Date d'octroi 2020-09-01
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van De Wardt, Cor
  • Krechting, Paulus Cornelis Hendrikus Maria
  • De Becker, Jan Frans Lodewijk
  • Nesvacil, Nicole
  • Kirisits, Christian
  • Pötter, Richard
  • Schmid, Maximilian Paul

Abrégé

Systems and methods for generating a radiation therapy treatment plan by using ultrasound images are disclosed. The method includes obtaining a first set of image data representing a first image of an anatomical region that includes a treatment applicator inserted into the anatomical region. The method further includes receiving tracking information indicating a position of the treatment applicator as represented in the first set of image data, obtaining a second set of image data representing a second image of the anatomical region, and combining at least a portion of the first set of image data with the second set of image data. One of the first set and the second set of image data is used to identify a target tissue portion in the anatomical region. The method further includes generating, based on the combined image data, treatment plan information for treating the target tissue portion in the anatomical region.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
  • A61B 8/12 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores dans des cavités ou des conduits du corps, p. ex. en utilisant des cathéters
  • A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
  • A61B 6/12 - Agencements pour détecter ou localiser des corps étrangers
  • A61B 8/08 - Applications cliniques
  • A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
  • A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
  • A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
  • A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux

25.

System and method for performing brachytherapy

      
Numéro d'application 15158564
Numéro de brevet 10195460
Statut Délivré - en vigueur
Date de dépôt 2016-05-18
Date de la première publication 2016-11-24
Date d'octroi 2019-02-05
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Woudstra, Bas
  • Henning, Johan

Abrégé

A system for transporting a source for brachytherapy may include a source guide, a detector, and a controller. The source guide may be configured to guide a source transport for transporting the source, wherein the source guide includes at least one electronic tag. The detector may be configured to detect a frequency signal generated by the at least one electronic tag, wherein the frequency signal varies when the source transport is proximate to the at least one electronic tag. The controller may be configured to receive the frequency signal from the detector and determine a path of the source transport based on the frequency signal. A method for transporting a source used for brachytherapy may include detecting a frequency signal generated by at least one electronic tag associated with a source guide configured to guide a source transport for transporting the source. The frequency may vary when the source transport is proximate to the at least one electronic tag. The method may further include determining a path of the source transport based on the frequency signal.

Classes IPC  ?

  • A61N 5/00 - Thérapie par radiations
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 90/98 - Moyens d’identification pour les patients ou les instruments, p. ex. étiquettes utilisant des moyens électromagnétiques, p. ex. transpondeurs

26.

BRACHYTHERAPY APPLICATORS HAVING ULTRASOUND ELEMENTS

      
Numéro d'application NL2016050248
Numéro de publication 2016/163885
Statut Délivré - en vigueur
Date de dépôt 2016-04-11
Date de publication 2016-10-13
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Krechting, Paulus Cornelis Hendrikus Maria
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • De Becker, Jan F.L.
  • Welberg, Anton J.G.

Abrégé

A brachytherapy system includes a brachytherapy applicator. The brachytherapy applicator includes an applicator tube and a radiation source configured to deliver radiation to a tumor. At least a portion of the applicator tube is configured to conform to at least a portion of a patient's anatomy. At least one ultrasound element or probe is coupled to or embedded with the applicator tube.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 8/12 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores dans des cavités ou des conduits du corps, p. ex. en utilisant des cathéters
  • A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
  • A61B 8/08 - Applications cliniques

27.

Brachytherapy position verification system and methods of use

      
Numéro d'application 14565807
Numéro de brevet 10293178
Statut Délivré - en vigueur
Date de dépôt 2014-12-10
Date de la première publication 2016-06-16
Date d'octroi 2019-05-21
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • De Vries, Frits
  • Van Appeldoorn, Adriaan

Abrégé

In one embodiment, a verification system for confirming the position of a conduit inserted within a patient may include an elongate control element dimensioned for insertion within the conduit. The control element has a proximal end and a distal end, and a verification element coupled to a distal region. The verification element may be configured to detect the presence of a reference marker associated with the conduit and communicate a signal indicative of the position of the reference marker relative to the verification element. The control element may also be configured to maneuver the verification element along a length of the conduit. The system may also include a drive device coupled to a proximal region of the control element for controlling movement of the control element through the conduit, a controller associated with the verification element and configured to communicate with the verification element, and a signal conductor for conducting the signal between the verification element and the controller.

Classes IPC  ?

  • A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
  • A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
  • A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

28.

ADVANCED APPLICATOR SYSTEMS AND METHODS

      
Numéro d'application IB2015002480
Numéro de publication 2016/087946
Statut Délivré - en vigueur
Date de dépôt 2015-12-04
Date de publication 2016-06-09
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Steller, Hendrik
  • Van Erp, Wilhelmus
  • Van Manen, Jan, Willem
  • Geheniau, Norbert, Johan Lukas

Abrégé

Systems, methods, and apparatuses are provided for an advanced gynecological applicator. In accordance with some embodiments, a brachytherapy applicator head and assembly is provided. The assembly may include two ovoid tubes configured to receive radiation sources, the two ovoid tubes combining to form a rounded applicator having a middle opening and comprising a plurality of needle holes to guide interstitial needles. The assembly may also include a central applicator tube configured to receive a radiation source that is located within the middle opening. Additionally, the assembly may include a vaginal cap that includes a tool-free connection to the two ovoid tubes and includes needle guides that align with the needle holes of the two ovoid tubes. The assembly may include a one-piece template for securing interstitial needles. The assembly may further include a tool- free connector to secure the two ovoid tubes to the central applicator tube.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

29.

Mobile X-ray unit

      
Numéro d'application 14971981
Numéro de brevet 09561009
Statut Délivré - en vigueur
Date de dépôt 2015-12-16
Date de la première publication 2016-04-14
Date d'octroi 2017-02-07
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Woudstra, Bas
  • De Jager, Wim

Abrégé

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an arm associated with the base. The arm may be configured to support an X-ray applicator having an X-ray tube. The arm may be articuable. The X-ray tube may include a target element configured to generate an X-ray beam and a collimator configured to shape the X-ray beam. The target element may be disposed at a set distance from the collimator.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
  • A61B 6/06 - Diaphragmes
  • H05G 1/26 - Mesure, commande ou protection
  • A61N 5/00 - Thérapie par radiations

30.

METHODS AND SYSTEMS FOR BRACHYTHERAPY PLANNING BASED ON IMAGING DATA

      
Numéro d'application IB2015001375
Numéro de publication 2015/181632
Statut Délivré - en vigueur
Date de dépôt 2015-05-28
Date de publication 2015-12-03
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van De Wardt, Cor
  • Krechting, Paulus Cornelis, Hendrikus Maria
  • De Becker, Jan Frans, Lodewijk
  • Nesvacil, Nicole
  • Pötter, Richard
  • Schmid, Maximilian, Paul
  • Kirisits, Christian

Abrégé

Systems and methods for generating a radiation therapy treatment plan by using ultrasound images are disclosed. The method comprises obtaining a first set of image data representing a first image of an anatomical region that includes a treatment applicator inserted into the anatomical region. The method further comprises receiving tracking information indicating a position of the treatment applicator as represented in the first set of image data, obtaining a second set of image data representing a second image of the anatomical region, and combining at least a portion of the first set of image data with the second set of image data. One of the first set and the second set of image data is used to identify a target tissue portion in the anatomical region. The method further comprises generating, based on the combined image data, treatment plan information for treating the target tissue portion in the anatomical region.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 8/12 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores dans des cavités ou des conduits du corps, p. ex. en utilisant des cathéters
  • A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
  • A61B 8/08 - Applications cliniques
  • A61B 8/14 - Écho-tomographie
  • A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
  • A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)

31.

Brachytherapy applicator device for insertion in a body cavity

      
Numéro d'application 14818936
Numéro de brevet 10029119
Statut Délivré - en vigueur
Date de dépôt 2015-08-05
Date de la première publication 2015-11-26
Date d'octroi 2018-07-24
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Mäkel, René Gerard Willem
  • Morssink, Pieter
  • Steller, Hendrik
  • Visscher, Arie Luite
  • Van De Wardt, Cor
  • Kuipers, Franciscus Antonius Maria

Abrégé

The invention relates to a brachytherapy applicator device for insertion in a body cavity. The applicator device comprises an applicator shaped for insertion in the body cavity; the applicator comprising connectable segments; at least one connectable part having a form following wall surface shaped to follow the body cavity, the wall surface having a multichannel groove structure, so as to guide a plurality of catheters along the grooves in the groove structure along the wall surface.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

32.

Brachytherapy instrument, an imaging system and a method of image acquisition

      
Numéro d'application 14651541
Numéro de brevet 10226232
Statut Délivré - en vigueur
Date de dépôt 2013-12-11
Date de la première publication 2015-11-19
Date d'octroi 2019-03-12
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Van De Wardt, Cor
  • Van Erp, Wilhelmus Petra Martinus Maria
  • Visscher, Luite

Abrégé

The invention relates to a brachytherapy instrument comprising a body, wherein the body is provided with at least one marker comprising a material suitable to be visualized using an ultrasonic and/or magnetic resonance imaging technique. The invention further relates to an image acquisition system and a method of image acquisition.

Classes IPC  ?

  • A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
  • A61B 8/08 - Applications cliniques
  • A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 17/34 - TrocartsAiguilles à ponction
  • A61B 90/96 - Moyens d’identification pour les patients ou les instruments, p. ex. étiquettes utilisant des symboles, p. ex. du texte utilisant des codes-barres
  • A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
  • A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

33.

Methods of making a medical applicator

      
Numéro d'application 14437305
Numéro de brevet 09662511
Statut Délivré - en vigueur
Date de dépôt 2013-10-25
Date de la première publication 2015-09-24
Date d'octroi 2017-05-30
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s) Krechting, Paulus Cornelis Hendrikus Maria

Abrégé

Embodiments of the disclosure are drawn to methods of forming an applicator body of an applicator for insertion into an anatomical cavity of a patient for delivering a treatment to the patient. In some instances, the method may include receiving a first three-dimensional image of the anatomical cavity, which was generated while the anatomical cavity contained an expandable container adjacent a tissue region of the patient, and while the expandable container was filled with fluid such that the container was expanded to substantially conform to the shape of at least a portion of the tissue region. The method also may include isolating, from the first three-dimensional image, a first sub-image corresponding to an image of the filled expanded container. The method further may include using the first sub-image as a design template for forming the applicator body for use with the patient.

Classes IPC  ?

  • B29C 41/02 - Façonnage par revêtement d'un moule, noyau ou autre support, c.-à-d. par dépôt de la matière à mouler et démoulage de l'objet forméAppareils à cet effet pour la fabrication d'objets de longueur définie, c.-à-d. d'objets séparés
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • B29C 33/38 - Moules ou noyauxLeurs détails ou accessoires caractérisés par la matière ou le procédé de fabrication
  • B29C 67/00 - Techniques de façonnage non couvertes par les groupes , ou
  • B33Y 10/00 - Procédés de fabrication additive
  • B33Y 80/00 - Produits obtenus par fabrication additive
  • B29L 31/00 - Autres objets particuliers
  • A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales

34.

Mobile X-ray unit

      
Numéro d'application 14697761
Numéro de brevet 09259596
Statut Délivré - en vigueur
Date de dépôt 2015-04-28
Date de la première publication 2015-08-13
Date d'octroi 2016-02-16
Propriétaire NUCLETRON OPERATIONS, B.V. (Pays‑Bas)
Inventeur(s) Jager, Wim De

Abrégé

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base and an arm associated with the base. The arm may be configured to support an X-ray applicator having an X-ray tube. The X-ray tube may be configured to generate an X-ray beam. The X-ray applicator may include an exit surface through which the X-ray beam passes in use. The X-ray unit may further include an applicator cap for covering at least the exit surface of the X-ray applicator.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

35.

Afterloading device, and use thereof

      
Numéro d'application 14283470
Numéro de brevet 09795804
Statut Délivré - en vigueur
Date de dépôt 2014-05-21
Date de la première publication 2014-11-27
Date d'octroi 2017-10-24
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Van Appeldoorn, Adriaan
  • Schuurman, Jeroen
  • Van Beek, Martin
  • Sollen, Finn
  • Henning, Johan
  • Visscher, Arie Luite

Abrégé

An afterloading device for effectuating a brachytherapy treatment, comprising a first elongated flexible transport element, arranged to maneuver a radiation source between a storage position inside the afterloading device and a treatment position outside the afterloading device, the afterloading device further comprising a second elongated flexible transport element, having at least one transducer, the second transport element being arranged to move the at least one transducer between a first transducer position and a second transducer position.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • G01T 1/02 - Dosimètres

36.

Mobile X-ray unit

      
Numéro d'application 14454882
Numéro de brevet 09724066
Statut Délivré - en vigueur
Date de dépôt 2014-08-08
Date de la première publication 2014-11-27
Date d'octroi 2017-08-08
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Van Der Veen, Johannes Simon
  • Woudstra, Bas
  • Henning, Johan

Abrégé

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include an X-ray applicator for emitting an X-ray beam for irradiating an object. The mobile X-ray unit may further include a phantom-based dosimetry system configured to perform a dosimetry check of the X-ray beam. The phantom-based dosimetry system may include two sets of dose meters, each set being positioned on a surface at a distinct depth. The mobile X-ray unit may also include a dosimetry control unit configured to receive measurements from the two sets of dose meters and determine whether the dosimetry check is passed based on the measurements.

Classes IPC  ?

  • A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • G01T 1/02 - Dosimètres
  • A61B 5/107 - Mesure de dimensions corporelles, p. ex. la taille du corps entier ou de parties de celui-ci

37.

Brachy Academy

      
Numéro d'application 1219106
Statut Enregistrée
Date de dépôt 2014-03-05
Date d'enregistrement 2014-03-05
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ?
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Education services; educational programs and workshops; e-learning. Medical services, namely providing medical information by the internet.

38.

Brachytherapy source assembly

      
Numéro d'application 14122853
Numéro de brevet 10166403
Statut Délivré - en vigueur
Date de dépôt 2012-06-01
Date de la première publication 2014-07-03
Date d'octroi 2019-01-01
Propriétaire Nuvletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Bakker, Pier
  • De Jager, Wim
  • Visscher, Arie Luite
  • Vreeken, Henk

Abrégé

An embodiment of the present disclosure is directed to a brachytherapy source assembly including a guiding wire and a brachytherapy capsule located at a distal end of the guiding wire. The capsule includes a chamber defined by a wall for holding a radioactive source. At least a portion of an exterior surface of the wall of the capsule includes at least one of a friction-reducing coating, a wear-resistant coating, and a wear-indication coating a coating.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

39.

A BRACHYTHERAPY INSTRUMENT, AN IMAGING SYSTEM AND A METHOD OF IMAGE ACQUISITION

      
Numéro d'application NL2013050889
Numéro de publication 2014/092570
Statut Délivré - en vigueur
Date de dépôt 2013-12-11
Date de publication 2014-06-19
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van De Wardt, Cor
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Visscher, Luite

Abrégé

The invention relates to a brachytherapy instrument comprising a body, wherein the body is provided with at least one marker comprising a material suitable to be visualized using an ultrasonic and/or magnetic resonance imaging technique. The invention further relates to an image acquisition system and a method of image acquisition.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)

40.

A GAMMA SOURCE TRACKING SYSTEM

      
Numéro d'application IB2013003078
Numéro de publication 2014/068405
Statut Délivré - en vigueur
Date de dépôt 2013-10-23
Date de publication 2014-05-08
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Krechting, Paulus Cornelis, Hendrikus Maria

Abrégé

Embodiments of the disclosure relate to a method for reconstructing a spatial position of a conduit arranged to accommodate a radiotherapeutic radioactive source, The method includes displacing an object emitting radiation inside the conduit prior to the administration of a treatment, detecting said radiation using detectors; generating data upon detecting the said radiation using a processor; and reconstructing the spatial position of the conduit by the processor based on the said data to identify a delivery path of the treatment.

Classes IPC  ?

  • A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

41.

A MEDICAL APPLICATOR AND METHODS OF MAKING

      
Numéro d'application IB2013002634
Numéro de publication 2014/068398
Statut Délivré - en vigueur
Date de dépôt 2013-10-25
Date de publication 2014-05-08
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Krechting, Paulus Cornelis, Hendrikus Maria

Abrégé

Embodiments of the present disclosure are directed to forming an applicator for insertion into an anatomica! cavity of a patient for delivering a treatment to the patient The method may include receiving a three-dimensionai image of the anatomical cavity, wherein the three-dimensional image is generated while the anatomical cavity contains an expandable container adjacent a tissue region of the patient. The container may be expanded when contained in the anatomical cavity to substantially conform to the shape of at least a portion of the tissue region forming at least a portion of the anatomical cavity. The method may further include isolating, from the three-dimensional image, a first sub-image corresponding to an image of the filled expanded container and using the sub-image as a design template for forming the applicator for use with the patient.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

42.

AN ESOPHAGUS APPLICATOR FOR BRACHYTHERAPY

      
Numéro d'application NL2013050755
Numéro de publication 2014/069991
Statut Délivré - en vigueur
Date de dépôt 2013-10-28
Date de publication 2014-05-08
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van Der Zanden, Maarten Antonius Christiaan
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Van De Wardt, Cor

Abrégé

The invention relates to an esophagus applicator for brachy therapy, comprising a molded plastic body comprising a proximal portion and a distal portion, said body accommodating a plurality of conduits, wherein at least one conduit from the said plurality of conduits is adapted to accommodate a displaceable radioactive source, and a further conduit from the said plurality of conduits is arranged to accommodate a guidewire, said proximal portion being connectable to an after loader device, said distal portion being substantially cone-shaped.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61M 25/09 - Fils de guidage

43.

A MODULAR APPLICATOR FOR BRACHYTHERAPY

      
Numéro d'application NL2013050750
Numéro de publication 2014/065667
Statut Délivré - en vigueur
Date de dépôt 2013-10-25
Date de publication 2014-05-01
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Martens, Tommy Robert Oscar
  • Van Wijck, Gaetan Stephan Marie
  • Van De Wardt, Cor

Abrégé

A modular applicator (10) for enabling a brachytherapy treatment comprising a central element (1a, 1b) and one or more of peripheral elements, wherein the central element is adapted with a fixation mechanism having a core (4) for affixing the said peripheral elements thereto, wherein the fixation mechanism prevents a rotational displacement of the peripheral elements attached to the core (4) of the fixation element with respect to the central element (1a, 1b).

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

44.

Modular applicator for brachytherapy

      
Numéro d'application 14063408
Numéro de brevet 09737729
Statut Délivré - en vigueur
Date de dépôt 2013-10-25
Date de la première publication 2014-05-01
Date d'octroi 2017-08-22
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Martens, Tommy Robert Oscar
  • Van Wijck, Gaetan Stephan Marie
  • Van De Wardt, Cor

Abrégé

Embodiments of the present disclosure relate to a modular applicator for enabling a brachytherapy treatment, comprising a central core and an outer sleeve, wherein the central core is adapted with a fixation mechanism for affixing the outer sleeve to the central core, wherein the outer sleeve is manufactured from a substantially rigid or shapeable material.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

45.

Modular applicator for brachytherapy

      
Numéro d'application 14063527
Numéro de brevet 09827443
Statut Délivré - en vigueur
Date de dépôt 2013-10-25
Date de la première publication 2014-05-01
Date d'octroi 2017-11-28
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Martens, Tommy Robert Oscar
  • Van Wijck, Gaetan Stephan Marie
  • Van De Wardt, Cor

Abrégé

A modular applicator for enabling a brachytherapy treatment comprising a central element and one or more of peripheral elements, wherein the central element is adapted with a fixation mechanism having a core for affixing the said peripheral elements thereto, wherein the fixation mechanism prevents a rotational displacement of the peripheral elements attached to the core of the fixation element with respect to the central element.

Classes IPC  ?

  • A61N 5/00 - Thérapie par radiations
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61M 25/02 - Dispositifs de maintien en position, p. ex. sur le corps

46.

A MODULAR APPLICATOR FOR BRACHYTHERAPY

      
Numéro d'application NL2013050749
Numéro de publication 2014/065666
Statut Délivré - en vigueur
Date de dépôt 2013-10-25
Date de publication 2014-05-01
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Martens, Tommy Robert Oscar
  • Van Wijck, Gaetan Stephan Marie
  • Van De Wardt, Cor

Abrégé

The invention relates to a modular applicator (15) for enabling a brachytherapy treatment, comprising a central core (8) and an outer sleeve (9), wherein the central core is adapted with a fixation mechanism (8a) for affixing the outer sleeve to the central core, wherein the outer sleeve is manufactured from a substantially rigid or shapeable material.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

47.

LUMENCARE

      
Numéro de série 86216056
Statut Enregistrée
Date de dépôt 2014-03-10
Date d'enregistrement 2015-06-02
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ? 10 - Appareils et instruments médicaux

Produits et services

Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy

48.

BRACHY ACADEMY

      
Numéro de série 79153325
Statut Enregistrée
Date de dépôt 2014-03-05
Date d'enregistrement 2015-08-11
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ?
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Educational services, namely, conducting educational programs, workshops, e-learning sessions and webcasts in the field of internal radiotherapy Medical services, namely, providing medical information by the internet

49.

Luneray

      
Numéro d'application 1182413
Statut Enregistrée
Date de dépôt 2013-09-18
Date d'enregistrement 2013-09-18
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ? 10 - Appareils et instruments médicaux

Produits et services

Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy, namely, medical apparatus for surgical interventions and applications; brachytherapy apparatus using ionising radiation for medical use, namely, pre-assembled sterile needle-catheter combinations for interstitial brachytherapy treatments.

50.

Luneray

      
Numéro d'application 164404900
Statut Enregistrée
Date de dépôt 2013-09-18
Date d'enregistrement 2019-07-11
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ? 10 - Appareils et instruments médicaux

Produits et services

(1) Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy, namely, catheters for surgical interventions and applications; brachytherapy apparatus using ionising radiation for medical use, namely, pre-assembled sterile needle-catheter combinations for interstitial brachytherapy treatments.

51.

LUNERAY

      
Numéro de série 79138745
Statut Enregistrée
Date de dépôt 2013-09-18
Date d'enregistrement 2014-05-06
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ? 10 - Appareils et instruments médicaux

Produits et services

Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy, namely, medical apparatus for surgical interventions and applications; brachytherapy apparatus using ionising radiation for medical use, namely, pre-assembled sterile needle-catheter combinations for interstitial brachytherapy treatments

52.

Brachy Academy

      
Numéro d'application 012131471
Statut Enregistrée
Date de dépôt 2013-09-11
Date d'enregistrement 2014-02-05
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ?
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Education services; educational programs and workshops; e-learning and webcasts. Medical services, namely providing medical information by the internet.

53.

Brachytherapy applicator device for insertion in a body cavity

      
Numéro d'application 13807552
Numéro de brevet 09132282
Statut Délivré - en vigueur
Date de dépôt 2011-06-30
Date de la première publication 2013-08-08
Date d'octroi 2015-09-15
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Mäkel, René Gerard Willem
  • Morssink, Pieter
  • Steller, Hendrik
  • Visscher, Arie Luite
  • Van De Wardt, Cor
  • Kuipers, Franciscus Antonius Maria

Abrégé

The invention relates to a brachytherapy applicator device for insertion in a body cavity. The applicator device comprises an applicator shaped for insertion in the body cavity; the applicator comprising connectable segments; at least one connectable part having a form following wall surface shaped to follow the body cavity, the wall surface having a multichannel groove structure, so as to guide a plurality of catheters along the grooves in the groove structure along the wall surface.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

54.

Apparatus and methods for radiation treatment of tissue surfaces

      
Numéro d'application 13765339
Numéro de brevet 08675815
Statut Délivré - en vigueur
Date de dépôt 2013-02-12
Date de la première publication 2013-06-20
Date d'octroi 2014-03-18
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Holt, Randall W.
  • Axelrod, Steve
  • Burnside, Robert R.
  • Neimeyer, Robert G.
  • Rusch, Tom

Abrégé

A device, system and method for administering radiation therapy to a tissue surface of a patient utilizes an applicator capable of controlled movement and repositioning over a selected area of tissue, under the control of a computer or controller. A servo-controlled manipulator can effect a raster scan of the desired area, such as an area of the skin, and this can be in any desired pattern such as serpentine, spiral, parallel but unidirectional, or irregular patterns. Preferably a third direction of control is included, i.e. a depth direction, with an appropriate form of depth sensor, a signal from which can be used to adjust the radiation source so that radiation of the tissue surface is consistent over varied contoured.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

55.

LumenCare Azure

      
Numéro d'application 011669397
Statut Enregistrée
Date de dépôt 2013-03-19
Date d'enregistrement 2013-08-14
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ? 10 - Appareils et instruments médicaux

Produits et services

Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy, namely, medical apparatus for surgical interventions and applications; treatment delivery positioning accessories, namely catheters for intraluminal brachytherapy treatments.

56.

Luneray

      
Numéro d'application 011669322
Statut Enregistrée
Date de dépôt 2013-03-19
Date d'enregistrement 2013-08-14
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ? 10 - Appareils et instruments médicaux

Produits et services

Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy, namely, medical apparatus for surgical interventions and applications; brachytherapy apparatus using ionising radiation for medical use, namely, pre-assembled sterile needle-catheter combinations for interstitial brachytherapy treatments.

57.

Applicators and methods for intraoperative treatment of proliferative diseases of the breast

      
Numéro d'application 13649257
Numéro de brevet 08529427
Statut Délivré - en vigueur
Date de dépôt 2012-10-11
Date de la première publication 2013-02-07
Date d'octroi 2013-09-10
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Francescatti, Darius
  • Jervis, James E.

Abrégé

A device for administering brachytherapy to a patient includes a vessel that may be in the form of a hollow cylindrical cup, for fleshing into and substantially filling the open-ended cavity. The vessel has a closed outer end, which may be a removable cover, and a source guide penetrates the closed outer end so as to extend deep into the vessel, to receive a radiation source in the source guide. A manipulator can be connected to the radiation source, and also to the source guide, for allowing several different types of manipulation of the source orientation and position within the vessel during the brachytherapy procedure.

Classes IPC  ?

  • A61N 5/01 - Dispositifs pour produire le mouvement de la source de radiation pendant la thérapie

58.

A GAMMA SOURCE TRACKING SYSTEM

      
Numéro d'application NL2012050518
Numéro de publication 2013/012331
Statut Délivré - en vigueur
Date de dépôt 2012-07-19
Date de publication 2013-01-24
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Henning, Johan
  • Woudstra, Bas
  • Schuurman, Jeroen

Abrégé

The invention relates to a radioactive source tracking system adapted to determine in real time a spatial position of a gamma source (la, lb) in a volume, comprising a set of spatially distributed position sensitive detectors (PSD) (5) operable in real time arranged about the volume, a real time computer system adapted to calculate the spatial position per time stamp of the gamma source in the said volume based on respective signals generated by said PSD's, wherein the radioactive source is represented by a 3D or 4D data stream in real time. The invention further relates to a method for tracking a radioactive gamma source and a computer program product for causing a processor to determine a real time 3D or a 4D spatial position of a gamma source.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • G01T 1/178 - Dispositions de circuits non adaptés à un type particulier de détecteur pour la mesure d'une activité spécifique en présence d'autres substances radioactives, p. ex. des substances naturelles, présentes dans l'air ou dans des liquides tels que l'eau de pluie

59.

Lightweight radiation absorbing shield

      
Numéro d'application 12800083
Numéro de brevet 08354658
Statut Délivré - en vigueur
Date de dépôt 2010-05-06
Date de la première publication 2013-01-15
Date d'octroi 2013-01-15
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Smith, Peter C.
  • Axelrod, Steve
  • Lovoi, Paul A.

Abrégé

A flexible, lightweight radiation absorbing sheet or shield includes heavy metal particles in one layer and mid-atomic number particles in another layer, the layer that will be adjacent to the patient. The shield is particularly intended for protection of the wearer and others from radiation emanating from a therapeutic source positioned within the patient's body. With the disclosed multi-layer shield construction, backscattered radiation off the heavy metal particle layer, affecting the patient's adjacent tissue, is minimized.

Classes IPC  ?

60.

BRACHYTHERAPY SOURCE ASSEMBLY

      
Numéro d'application NL2012050386
Numéro de publication 2012/165964
Statut Délivré - en vigueur
Date de dépôt 2012-06-01
Date de publication 2012-12-06
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Bakker, Pier
  • De Jager, Wim
  • Visscher, Arie Luite
  • Vreeken, Henk

Abrégé

The invention is directed to a brachytherapy source assembly, to a kit of parts, to a method for preparing a brachytherapy source assembly, to uses of a specific coating, and to a brachytherapy treatment. The brachytherapy source assembly of the invention comprises a push/pull wire and at the distal end thereof a capsule suitable for brachytherapy, wherein said capsule comprises a chamber for holding one or more radioactive sources, said chamber being defined by a wall, and wherein at least part of the exterior surface of the wall of the capsule comprises a coating, the coating comprising one or more selected from TiN, TiCN, TiCrN, CrN, TiA1CrN, DLC, and MοS2, wherein said capsule is attached to the push/pull wire or wherein said capsule is comprised in the push/pull wire.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

61.

ELECTRONIC BRACHYTHERAPY SYSTEM

      
Numéro de série 85780989
Statut Enregistrée
Date de dépôt 2012-11-16
Date d'enregistrement 2013-07-09
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Classes de Nice  ? 10 - Appareils et instruments médicaux

Produits et services

RADIATION THERAPY APPARATUS, NAMELY A MINIATURE ELECTRONIC X-RAY TUBE, A BALLOON APPLICATOR AND CATHETER FOR RECEIVING THE MINIATURE X-RAY TUBE TO ADMINISTER RADIATION TO A PATIENT, AN ELECTRONIC CONTROLLER FOR THE X-RAY TUBE AND FOR THE BALLOON APPLICATOR, AND A FLEXIBLE XRAY SHIELD FOR USE ON A PATIENT TO CONTAIN RADIATION

62.

ESTEYA

      
Numéro d'application 1124478
Statut Enregistrée
Date de dépôt 2012-05-21
Date d'enregistrement 2012-05-21
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ?
  • 05 - Produits pharmaceutiques, vétérinaires et hygièniques
  • 10 - Appareils et instruments médicaux
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Pharmaceutical products, especially for skin cancer. Surgical and medical devices and instruments and diagnosis devices, especially for skin cancer. Medical services, especially related to skin cancer.

63.

Mobile X-ray unit

      
Numéro d'application 13335414
Numéro de brevet 08520801
Statut Délivré - en vigueur
Date de dépôt 2011-12-22
Date de la première publication 2012-06-28
Date d'octroi 2013-08-27
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Henning, Johan

Abrégé

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit, a power supply, and a cooler. The mobile X-ray unit further including an articulated arm associated with the base and coupled to an X-ray applicator. The X-ray applicator including an X-ray tube having an anode for generating an acceleration field and a target element for generating an X-ray beam, wherein a longitudinal axis of the anode is substantially parallel to a longitudinal axis of the X-ray tube.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

64.

A MOBILE X-RAY UNIT

      
Numéro d'application NL2011050870
Numéro de publication 2012/087126
Statut Délivré - en vigueur
Date de dépôt 2011-12-21
Date de publication 2012-06-28
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Henning, Johan

Abrégé

The invention relates to a mobile X-ray unit(10) comprising a base (2) for accommodating a control unit, a power supply and a cooler and further comprising an articulated displaceable arm (4a) supporting an X-ray applicator (4) comprising an X-ray tube having a longitudinal axis, said X-ray applicator being connected to the base, the X-ray tube comprising an anode for generating an acceleration field and a target for generating an X-ray beam, the anode being disposed substantially parallel to the longitudinal axis of the X-ray tube. The invention further relates to a method of manufacturing a mobile X-ray tube and a method of delivering an X-ray beam.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

65.

A MOBILE X-RAY UNIT

      
Numéro d'application NL2011050872
Numéro de publication 2012/087127
Statut Délivré - en vigueur
Date de dépôt 2011-12-21
Date de publication 2012-06-28
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Woudstra, Bas
  • De Jager, Wim

Abrégé

The invention relates to a mobile X-ray unit (10) comprising a base(2) for accommodating a control unit, a power supply and a cooler and further comprising an articulated displaceable arm (4a) supporting an X-ray applicator (4) provided with an X-ray tube, said X-ray applicator being connected to the base, the X-ray tube comprising a target for generating an X-ray beam and a collimator for shaping the generated X-ray beam, a distance between the target and the collimator being in the range between 4 and 10 cm.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

66.

A MOBILE X-RAY UNIT

      
Numéro d'application NL2011050880
Numéro de publication 2012/087133
Statut Délivré - en vigueur
Date de dépôt 2011-12-21
Date de publication 2012-06-28
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Henning, Johan
  • Woudstra, Bas

Abrégé

The invention relates to a mobile X-ray unit (10) comprising a base(2) for accommodating a control unit and a power supply further comprising an articulated displaceable arm (4a) supporting an X-ray applicator(4) having an X-ray tube, said X-ray applicator being connected to the base using a flexible cable (3), wherein the X-ray tube comprises a target for generating an X-ray beam (8a), a collimator for shaping the generated X- ray beam and an exit surface (8) through which the X-ray beam passes in use, wherein the X-ray unit further comprises an indicator for providing a visual indication of at least a portion of the X-ray beam emitted from the exit surface.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

67.

Mobile X-ray unit

      
Numéro d'application 13335712
Numéro de brevet 08995616
Statut Délivré - en vigueur
Date de dépôt 2011-12-22
Date de la première publication 2012-06-28
Date d'octroi 2015-03-31
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Van Der Veen, Johannes Simon
  • Woudstra, Bas
  • Henning, Johan

Abrégé

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an articulated arm associated with the base and coupled to the X-ray applicator. The X-ray applicator may have an X-ray tube configured to emit an X-ray beam through an exit window to irradiate an object. The mobile X-ray unit may further include a dosimetry system adapted for real time dosimetry.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • H05G 1/28 - Mesure ou enregistrement du temps d'exposition effectifComptage du nombre des expositionsMesure du temps d'exposition nécessaire
  • A61N 5/00 - Thérapie par radiations
  • H01J 35/00 - Tubes à rayons X

68.

Mobile X-ray unit

      
Numéro d'application 13335830
Numéro de brevet 08929511
Statut Délivré - en vigueur
Date de dépôt 2011-12-22
Date de la première publication 2012-06-28
Date d'octroi 2015-01-06
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van Der Veen, Johannes Simon
  • Woudstra, Bas
  • Henning, Johan

Abrégé

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit configured to control an X-ray applicator and a power supply configured to supply power to the X-ray applicator. The mobile X-ray unit may further include an articulated arm associated with the base. The arm may be configured to support the X-ray applicator. The X-ray applicator may have an X-ray tube for emitting an X-ray beam for irradiating an object. The mobile X-ray unit may further include a phantom-based dosimetry system configured to perform a dosimetry check of the X-ray beam.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • H05G 1/28 - Mesure ou enregistrement du temps d'exposition effectifComptage du nombre des expositionsMesure du temps d'exposition nécessaire
  • A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations

69.

Mobile X-ray unit

      
Numéro d'application 13335863
Numéro de brevet 09036787
Statut Délivré - en vigueur
Date de dépôt 2011-12-22
Date de la première publication 2012-06-28
Date d'octroi 2015-05-19
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) De Jager, Wim

Abrégé

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base and an arm associated with the base. The arm may be configured to support an X-ray applicator having an X-ray tube. The X-ray tube may be configured to generate an X-ray beam. The X-ray applicator may include an exit surface through which the X-ray beam passes in use. The X-ray unit may further include an applicator cap for covering at least the exit surface of the X-ray applicator.

Classes IPC  ?

  • H01J 5/18 - Fenêtres perméables aux rayons X, aux rayons gamma ou aux particules
  • H01J 35/16 - EnceintesRécipientsBlindages associés
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • H05G 1/04 - Montage du tube à rayons X à l'intérieur d'une gaine fermée

70.

Method for identifying the location at least one treatment channel from a group of a plurality of treatment channels as well as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body

      
Numéro d'application 13411132
Numéro de brevet 09364685
Statut Délivré - en vigueur
Date de dépôt 2012-03-02
Date de la première publication 2012-06-28
Date d'octroi 2016-06-14
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Kindlein, Johann

Abrégé

The invention relates to a method for identifying the location at least one treatment channel from a group of a plurality of treatment channels as wells as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body. C comparing said reconstructed location said pre-planned plurality of locations. Furthermore the system according to the invention is characterized in that identifying means are present for identifying the location of at least one treatment channel from said group of said plurality of inserted treatment channels and comparing said identified location with one or more of said pre-planned locations present in said treatment plan.

Classes IPC  ?

  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)

71.

A MOBILE X-RAY UNIT

      
Numéro d'application NL2011050875
Numéro de publication 2012/087129
Statut Délivré - en vigueur
Date de dépôt 2011-12-21
Date de publication 2012-06-28
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Verhaar, Thamar Jacinthe Sarah
  • Van Schaik, Sander-Willem
  • Hekkenberg, Sebastiaan Willem

Abrégé

The invention relates to a mobile X-ray unit comprising a base (2), a mast (5) cooperating with the base and an articulated arm (4a), mechanically coupled to the mast and supporting an X-ray applicator (4) provided with an X-ray tube, the mast (5) being displaceable with respect the base (2) in an upward direction, the articulated arm (4a) comprising a ball joint (6b) at one end and a rotational joint (6a) at another end for adjusting a spatial position of the X-ray applicator (4) in use.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

72.

A MOBILE X-RAY UNIT

      
Numéro d'application NL2011050877
Numéro de publication 2012/087130
Statut Délivré - en vigueur
Date de dépôt 2011-12-21
Date de publication 2012-06-28
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) De Jager, Wim

Abrégé

The invention relates to a mobile X-ray unit (10) comprising a base (2) for accommodating a control unit and a power supply, further comprising an articulated displaceable arm (4a) supporting an X-ray applicator (4) provided with an X-ray tube, the X-ray applicator comprising an exit surface through which the X-ray beam passes in use and an applicator cap for covering at least the exit surface.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

73.

A MOBILE X-RAY UNIT

      
Numéro d'application NL2011050878
Numéro de publication 2012/087131
Statut Délivré - en vigueur
Date de dépôt 2011-12-21
Date de publication 2012-06-28
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van Der Veen, Johannes Simon
  • Woudstra, Bas
  • Henning, Johan

Abrégé

The invention relates to a mobile X-ray unit comprising a base (2) for accommodating a control unit and a power supply further comprising an articulated displaceable arm (4a) supporting an X-ray applicator (4) having an X-ray tube for emitting an X-ray beam (8a) through an exit window (8) for irradiating an object, wherein the X-ray unit further comprises a phantom- based dosimetry system (9a, 9b, 9c) adapted to perform the on-line or real-time dosimetry check of the X-ray beam.

Classes IPC  ?

  • A61N 5/00 - Thérapie par radiations
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 6/54 -

74.

A MOBILE X-RAY UNIT

      
Numéro d'application NL2011050879
Numéro de publication 2012/087132
Statut Délivré - en vigueur
Date de dépôt 2011-12-21
Date de publication 2012-06-28
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van Der Veen, Johannes Simon
  • Woudstra, Bas
  • Henning, Johan

Abrégé

The invention relates to a mobile X-ray unit (10) comprising a base(2) for accommodating a control unit and a power supply further comprising an articulated displaceable arm (4a) supporting an X-ray applicator(4) having an X-ray tube for emitting an X-ray beam (8a) through an exit window (8) for irradiating an object, the X-ray unit further comprises a built-in dosimetry system (9) adapted to carry out the on-line or real time dosimetry.

Classes IPC  ?

  • A61N 5/00 - Thérapie par radiations
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • H05G 1/44 - Commande du temps d'exposition en utilisant des dispositions pour interrompre lorsqu'une dose prédéterminée de radiation a été appliquée, p. ex. dans lequel l'instant d'interruption est déterminé par la mesure de l'énergie électrique fournie au tube dans lequel l'instant d'interruption est déterminé directement par la quantité de rayonnement

75.

ESTEYA

      
Numéro de série 79116060
Statut Enregistrée
Date de dépôt 2012-05-21
Date d'enregistrement 2013-07-16
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Classes de Nice  ?
  • 05 - Produits pharmaceutiques, vétérinaires et hygièniques
  • 10 - Appareils et instruments médicaux
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

[ Pharmaceutical preparations for treatment of skin cancer ] [ Surgical and ] medical devices [ and instruments and diagnosis devices ] used in the treatment of skin cancer, namely, medical x-ray [ apparatus and medical ] radiation [ apparatus to deliver x-ray radiation for surface ] * treatment apparatus for skin * brachytherapy procedures [ Medical services, especially related to skin cancer ]

76.

Method and apparatus for determining the position of a surgical tool relative to a target volume inside an animal body

      
Numéro d'application 13347225
Numéro de brevet 09730608
Statut Délivré - en vigueur
Date de dépôt 2012-01-10
Date de la première publication 2012-05-03
Date d'octroi 2017-08-15
Propriétaire Nucletron Operations, B.V. (Pays‑Bas)
Inventeur(s)
  • Lugt, Wilco Van Der
  • Schuurman, Jeroen
  • Henning, Johan
  • Kwa, Stefan
  • Kindlein, Johann

Abrégé

The invention relates to a method for determining the position of a surgical tool relative to a target volume inside an animal body according to a pre-plan comprising the steps of i) obtaining a plurality of two-dimensional images of said target volume using imaging means, each 2D-image being represented by an image data slice I(x,y,z); ii) reconstructing from said plurality of image data slices I(x,y,z) a three-dimensional image of said target volume using transformation means, said 3D-image being represented by a volumetric image data array V(x,y,z); iii) displaying said three-dimensional image of said target volume to an user using displaying means.

Classes IPC  ?

  • A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
  • A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
  • G06T 11/00 - Génération d'images bidimensionnelles [2D]
  • A61B 6/06 - Diaphragmes
  • A61B 8/12 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores dans des cavités ou des conduits du corps, p. ex. en utilisant des cathéters
  • A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
  • A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 8/08 - Applications cliniques
  • A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

77.

Proportional attenuation of radiation in brachytheraphy treatment

      
Numéro d'application 13291854
Numéro de brevet 09055972
Statut Délivré - en vigueur
Date de dépôt 2011-11-08
Date de la première publication 2012-03-01
Date d'octroi 2015-06-16
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Axelrod, Steve
  • Burnside, Robert R.
  • Lovoi, Paul A.

Abrégé

Attenuating masks for selective attenuation of radiation, particularly from an x-ray source in brachytherapy, employ materials having atomic number in a specific range, so as to attenuate radiation dose intensity generally proportionally through a range of distance from the source. Some preferred attenuation materials are silver and molybdenum. A set of small masks can be provided for a particular design of catheter that holds a radiation source, each mask having a size and shape to define a different solid angle of masking, so that in a brachytherapy procedure, sensitive tissue such as bone or skin can be protected by proper selection of and positioning of the attenuating mask, to reduce the dose intensity to that tissue.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)

78.

Components and assembly for performing brachytherapy treatment of tumour tissue in a human and animal body

      
Numéro d'application 13262629
Numéro de brevet 09623261
Statut Délivré - en vigueur
Date de dépôt 2010-03-22
Date de la première publication 2012-02-02
Date d'octroi 2017-04-18
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Van De Wardt, Cor
  • Buijs, Emil Matthijs
  • Visscher, Arie Luite

Abrégé

The invention relates to an assembly for performing brachytherapy treatment of tumor tissue in a human or animal body comprising an intracavitary component and at least one guiding unit, said at least one guiding unit exhibiting a longitudinal axis and being connectable to said intracavitary component, and wherein said at least one guiding unit is provided with coupling means for coupling at least one interstitial needle-assembly for delivering treatment to said tumor tissue. The assembly has coupling/uncoupling means arranged to allow a displacement of said at least one interstitial needle-assembly in a direction transverse to said longitudinal axis and to prevent a displacement of said at least one interstitial needle-assembly in a direction parallel to or a pre-defined angle to said longitudinal axis. This coupling principle allows for the preparation of the guiding unit before the patient is being hospitalized and positioned in the treatment room and will prevent the unwanted uncoupling of the interstitial needle-assembly during the actual treatment being performed, further reducing the risk of adversely affected treatment parameters (location and duration of the radiation being administered to the patient).

Classes IPC  ?

  • A61M 36/10 - Application utéro-vaginale ou pelvienne
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61M 25/01 - Introduction, guidage, avance, mise en place ou maintien en position des cathéters
  • A61M 37/00 - Autres appareils pour introduire des agents dans le corpsPercutanisation, c.-à-d. introduction de médicaments dans le corps par diffusion à travers la peau
  • A61B 90/11 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures pour la chirurgie stéréotaxique, p. ex. système stéréotaxique à cadre avec des guides pour aiguilles ou instruments, p. ex. des glissières courbes ou des articulations à rotule
  • A61B 17/42 - Instruments ou procédés de gynécologie ou d'obstétrique
  • A61B 17/34 - TrocartsAiguilles à ponction

79.

BRACHYTHERAPY APPLICATOR DEVICE FOR INSERTION IN A BODY CAVITY

      
Numéro de document 02803755
Statut Délivré - en vigueur
Date de dépôt 2011-06-30
Date de disponibilité au public 2012-01-05
Date d'octroi 2018-11-13
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Makel, Rene Gerard Willem
  • Morssink, Pieter
  • Steller, Hendrik
  • Visscher, Arie Luite
  • Van De Wardt, Cor
  • Kuipers, Franciscus Antonius Maria

Abrégé

The invention relates to a brachytherapy applicator device for insertion in a body cavity. The applicator device comprises an applicator shaped for insertion in the body cavity; the applicator comprising connectable segments; at least one connectablepart having a form following wall surface shaped to follow the body cavity, the wall surface having a multichannel groove structure, so as to guide a plurality of catheters along the grooves in the groove structure along the wall surface.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

80.

BRACHYTHERAPY APPLICATOR DEVICE FOR INSERTION IN A BODY CAVITY

      
Numéro d'application NL2011050474
Numéro de publication 2012/002815
Statut Délivré - en vigueur
Date de dépôt 2011-06-30
Date de publication 2012-01-05
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Mäkel, René Gerard Willem
  • Morssink, Pieter
  • Steller, Hendrik
  • Visscher, Arie Luite
  • Van De Wardt, Cor
  • Kuipers, Franciscus Antonius Maria

Abrégé

The invention relates to a brachytherapy applicator device for insertion in a body cavity. The applicator device comprises an applicator shaped for insertion in the body cavity; the applicator comprising connectable segments; at least one connectable part having a form following wall surface shaped to follow the body cavity, the wall surface having a multichannel groove structure, so as to guide a plurality of catheters along the grooves in the groove structure along the wall surface.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

81.

Apparatus and methods for radiation treatment of tissue surfaces

      
Numéro d'application 12802744
Numéro de brevet 08374313
Statut Délivré - en vigueur
Date de dépôt 2010-06-11
Date de la première publication 2011-12-15
Date d'octroi 2013-02-12
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Holt, Randall W.
  • Axelrod, Steve
  • Burnside, Robert
  • Neimeyer, Robert G.
  • Rusch, Thomas W.

Abrégé

A device, system and method for administering radiation therapy to a tissue surface of a patient utilizes an applicator capable of controlled movement and repositioning over a selected area of tissue, under the control of a computer or controller. A servo-controlled manipulator can effect a raster scan of the desired area, such as an area of the skin, and this can be in any desired pattern such as serpentine, spiral, parallel but unidirectional, or irregular patterns. Preferably a third direction of control is included, i.e. a depth direction, with an appropriate form of depth sensor, a signal from which can be used to adjust the radiation source so that radiation of the tissue surface is consistent over varied contoured.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • H05G 1/02 - Détails de structure

82.

Assembly for performing brachytherapy treatment of a tumour tissue in an animal body

      
Numéro d'application 13120282
Numéro de brevet 08834339
Statut Délivré - en vigueur
Date de dépôt 2009-09-23
Date de la première publication 2011-09-15
Date d'octroi 2014-09-16
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Hannoun-Levi, Jean-Michel
  • Van De Wardt, Cor
  • Visscher, Arie Luite
  • Binnekamp, Dirk

Abrégé

This invention relates to an assembly for performing brachytherapy treatment of tumour tissue in an animal body comprising at least a longitudinally extending intracavitary component and at least a guiding unit which extends at least partly parallel to said intracavitary component. Said guiding unit comprises at least one interstitial needle for guiding a radiation source into the tumour tissue. Said guiding unit is tubular over at least a longitudinal distance sufficient that in use a proximal end of said guiding unit is situated outside said body to be treated, while a distal end of said guiding unit is situated in situ close to or adjacent the tumour tissue.

Classes IPC  ?

  • A61N 5/00 - Thérapie par radiations
  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

83.

EBX

      
Numéro de série 85081466
Statut Enregistrée
Date de dépôt 2010-07-09
Date d'enregistrement 2012-04-10
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Classes de Nice  ? 10 - Appareils et instruments médicaux

Produits et services

RADIATION THERAPY APPARATUS, namely, A MINIATURE ELECTRONIC X-RAY TUBE, A BALLOON APPLICATOR AND CATHETER FOR RECEIVING THE MINIATURE X-RAY TUBE TO ADMINISTER RADIATION TO A PATIENT, AN ELECTRONIC CONTROLLER FOR THE X-RAY TUBE AND FOR THE BALLOON APPLICATOR, AND A FLEXIBLE X-RAY SHIELD FOR USE ON A PATIENT TO CONTAIN RADIATION, ALL SOLD AS A UNIT

84.

Applicators and methods for intraoperative treatment of proliferative diseases of the breast

      
Numéro d'application 12156298
Numéro de brevet 08303476
Statut Délivré - en vigueur
Date de dépôt 2008-05-30
Date de la première publication 2009-12-03
Date d'octroi 2012-11-06
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Francescatti, Darius
  • Jervis, James E.

Abrégé

A device for administering brachytherapy to a patient includes a vessel that may be in the form of a hollow cylindrical cup, for fleshing into and substantially filling the open-ended cavity. The vessel has a closed outer end, which may be a removable cover, and a source guide penetrates the closed outer end so as to extend deep into the vessel, to receive a radiation source in the source guide. A manipulator can be connected to the radiation source, and also to the source guide, for allowing several different types of manipulation of the source orientation and position within the vessel during the brachytherapy procedure.

Classes IPC  ?

  • A61N 5/01 - Dispositifs pour produire le mouvement de la source de radiation pendant la thérapie

85.

Proportional attenuation of radiation in brachytherapy treatment

      
Numéro d'application 12072620
Numéro de brevet 08062203
Statut Délivré - en vigueur
Date de dépôt 2008-02-26
Date de la première publication 2009-08-27
Date d'octroi 2011-11-22
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Axelrod, Steve
  • Burnside, Robert R.
  • Lovoi, Paul A.

Abrégé

Attenuating masks for selective attenuation of radiation, particularly from an x-ray source in brachytherapy, employ materials having atomic number in a specific range, so as to attenuate radiation dose intensity generally proportionally through a range of distance from the source. Some preferred attenuation materials are silver and molybdenum. A set of small masks can be provided for a particular design of catheter that holds a radiation source, each mask having a size and shape to define a different solid angle of masking, so that in a brachytherapy procedure, sensitive tissue such as bone or skin can be protected by proper selection of and positioning of the attenuating mask, to reduce the dose intensity to that tissue.

Classes IPC  ?

86.

Balloon brachytherapy applicator and method

      
Numéro d'application 11871116
Numéro de brevet 07727137
Statut Délivré - en vigueur
Date de dépôt 2007-10-11
Date de la première publication 2009-08-20
Date d'octroi 2010-06-01
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Francescatti, Darius
  • Hoffmann, David J.
  • Tremberth, Scott
  • Klein, Michael
  • Lovoi, Paul A.
  • Jervis, James E.

Abrégé

Methods and applicator apparatus are disclosed for brachytherapy treatment of tissue surrounding a cavity in a patient, particularly a resection cavity. In treatment regimes requiring recovery time between successive radiation treatments, applicators of the invention are retained under the skin, with the skin allowed to at least partially heal, and are re-accessed later for one or more subsequent treatments. To reduce patient discomfort an anesthetic agent can be infused through the applicator to patient tissue, for insertion, balloon inflation or removal of the applicator.

Classes IPC  ?

  • A61M 36/00 - Application de matériau radioactif au corps
  • A61M 36/04 - Dispositions spécialement adaptées pour introduire, p. ex. par inhalation ou par injection, un matériau radioactif dans le corps
  • A61N 5/00 - Thérapie par radiations

87.

IPSA

      
Numéro d'application 1007099
Statut Enregistrée
Date de dépôt 2009-05-11
Date d'enregistrement 2009-05-11
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Classes de Nice  ?
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 42 - Services scientifiques, technologiques et industriels, recherche et conception

Produits et services

Scientific apparatus and instruments for use in the field of cancer diagnostics and treatment and brachytherapy, including image guided brachytherapy and adaptive brachytherapy; apparatus and instruments in the form of computer hardware and computer software for use in radio oncology; brachytherapy treatment systems comprised of medical software and hardware for use in performing intraluminal, interstitial and intraoperative procedures and outpatient treatment and medical computer software and apparatus for imaging and real time imaging; brachytherapy apparatus using ionising radiation for scientific purposes and not for medical use. Medical apparatus and instruments for use in the field of cancer diagnostics and treatment and brachytherapy, including image guided brachytherapy and adaptive brachytherapy, afterloaders, applicators, needles, catheters and templates, all for use in radio oncology, cancer and brachytherapy treatment; medical apparatus for surgical interventions and applications; brachytherapy apparatus using ionising radiation for medical use; bio-absorbable materials for medical and surgical use, including implantable radiation therapy devices consisting of radioactive seeds and a bio-absorbable carrier assembly; permanent implants of artificial materials; medical disposables, including disposable syringes and applicators; nanomaterials and nano sources for medical use, namely a delivery system comprising a device that produces nanomaterials and nano sources to diagnose or treat cancer. Design, development, programming and updating of computer hardware and computer software in the medical field; installation, maintenance and repair of computer software in the medical field; scientific and technological services, namely research and design services.

88.

Brachytherapy apparatus and method for use with minimally invasive surgeries of the lung

      
Numéro d'application 11978147
Numéro de brevet 08409070
Statut Délivré - en vigueur
Date de dépôt 2007-10-26
Date de la première publication 2009-04-30
Date d'octroi 2013-04-02
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Carol, Mark P.
  • Jervis, James E.
  • Lovoi, Paul A.

Abrégé

Brachytherapy treatment of a patient's lung tissue following resection is effected using a balloon applicator which is inserted, normally through the same opening used for the surgery, through the chest wall and into the cavity. The lung and chest openings are closed around the applicator and generally sealed around the applicator. A suction port is provided, in a suction circuit of the applicator, to withdraw fluid from the pleural cavity, at intervals as needed, to assure that the lung can be inflated. Different embodiments of suction circuits are disclosed. A bronchial applicator and method are also disclosed.

Classes IPC  ?

89.

Customized gynecological brachytherapy applicator and method

      
Numéro d'application 11809836
Numéro de brevet 07678040
Statut Délivré - en vigueur
Date de dépôt 2007-05-31
Date de la première publication 2008-12-04
Date d'octroi 2010-03-16
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Francescatti, Darius
  • Lovoi, Paul A.

Abrégé

A customized gynecological brachytherapy applicator is formed by placing a molded balloon, which is secured to a handle, into a vaginal cavity and then filling the mold balloon with a settable liquid material. The material may be an expanding foam or any other form of curable material that becomes solid, rigid or pliable, when set by chemical action, temperature change, oxidation, a curing means such as a light, or other curing regime. The mold balloon can be elastic or inelastic, depending on the degree to which the applicator is to conform its external surfaces to the vaginal contours. One or more lumina are provided in the set filler material to receive a radiation source, with additional lumina optionally provided for purposes such as drainage or administration of therapeutic agents. The applicator may be withdrawn and reinserted into the vagina during treatment, and selected tissues adjacent to the applicator are irradiated in accordance with a radiation prescription.

Classes IPC  ?

90.

Customized gynecological brachytherapy applicator and method

      
Numéro d'application 11805065
Numéro de brevet 07744521
Statut Délivré - en vigueur
Date de dépôt 2007-05-21
Date de la première publication 2008-11-27
Date d'octroi 2010-06-29
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Francescatti, Darius
  • Lovoi, Paul A.

Abrégé

A customized gynecological brachytherapy applicator is formed by placing a molded balloon, which is secured to a handle, into a vaginal cavity and then filling the mold balloon with a settable liquid material. The material may be an expanding foam or any other form of curable material that becomes solid, rigid or pliable, when set by chemical action, temperature change, oxidation, a curing means such as a light, or other curing regime. The mold balloon can be elastic or inelastic, depending on the degree to which the applicator is to conform its external surfaces to the vaginal contours. One or more lumina are provided in the set filler material to receive a radiation source, with additional lumina optionally provided for purposes such as drainage or administration of therapeutic agents. The applicator may be withdrawn and reinserted into the vagina during treatment, and selected tissues adjacent to the applicator are irradiated in accordance with a radiation prescription.

Classes IPC  ?

91.

Apparatus for introducing catheters or needles into a body part

      
Numéro d'application 11564733
Numéro de brevet 08162884
Statut Délivré - en vigueur
Date de dépôt 2006-11-29
Date de la première publication 2008-10-23
Date d'octroi 2012-04-24
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Van'T Hooft, Eric

Abrégé

A template, to be provided at some distance from the skin, provided with multiple guide holes for needles or catheters of which one or more can anchor in the prostate. The template is provided with a locking mechanism so that, after placement, the anchored needles keep all needles in their original places. The above-described method of fixedly positioning a treatment template prevents the needles from moving due to swelling of the tissue in the prostate, which causes the irradiation source, which is later provided in the needles, to improperly irradiate the area.

Classes IPC  ?

  • A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
  • A61M 5/32 - AiguillesParties constitutives des aiguilles relatives au raccordement de celles-ci à la seringue ou au manchonAccessoires pour introduire l'aiguille dans le corps ou l'y maintenirDispositifs pour la protection des aiguilles

92.

Method for adaptive radiation treatment of breast tissue surrounding a cancer resection cavity of arbitrary shape

      
Numéro d'application 11932974
Numéro de brevet 08262555
Statut Délivré - en vigueur
Date de dépôt 2007-10-31
Date de la première publication 2008-06-26
Date d'octroi 2012-09-11
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Jervis, James E.
  • Lovoi, Paul A.

Abrégé

Radiation treatment methods for breast cancer following resection, both intraoperative and post operative, involve mapping preferably using an electronic x-ray source, and can include rotation of a direction source. By using a very rapid, near-instantaneous method of pathology of tissue margins following resection, the invention carries out intraoperative radiation treatment, preferably with the patient remaining anesthetized. Whether or not radiation is intraoperative, the invention preferably includes a mapping procedure using an electronic source that is progressed through the resection cavity while radiation dose is sensed at one or more points, to determine the shape of the resection cavity.

Classes IPC  ?

93.

Transport cable and source capsule with safe connecting construction for internally irradiating patients

      
Numéro d'application 11876419
Numéro de brevet 10933255
Statut Délivré - en vigueur
Date de dépôt 2007-10-22
Date de la première publication 2008-05-22
Date d'octroi 2021-03-02
Propriétaire Nucletron Operations B.V. (Pays‑Bas)
Inventeur(s)
  • Van'T Hooft, Eric
  • Van Zwol, Libbe

Abrégé

A source guide apparatus for brachytherapy application, wherein the source guide apparatus is provided with a source capsule, a guidewire for moving the source capsule through a catheter, a mechanical connection between the guidewire and the source capsule, wherein the source guide apparatus is provided with a sleeve which is attached on the capsule, wherein the sleeve envelops at least a part of the mechanical connection.

Classes IPC  ?

  • A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
  • A61M 36/04 - Dispositions spécialement adaptées pour introduire, p. ex. par inhalation ou par injection, un matériau radioactif dans le corps

94.

Radiation therapy apparatus with selective shielding capability

      
Numéro d'application 11471277
Numéro de brevet 07686755
Statut Délivré - en vigueur
Date de dépôt 2006-06-19
Date de la première publication 2008-01-10
Date d'octroi 2010-03-30
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Smith, Peter C.
  • Klein, Michael
  • Hausen, Heike
  • Lovoi, Paul A.

Abrégé

Brachytherapy applicators incorporate various forms of selective shielding devices for controlling the direction and intensity of radiation directed at a patient's tissue. In some forms the applicators include a retractable sheath, in some a series of retractable fingers. In other forms the applicator, having an inflatable balloon, has a shield which is retractable from a position adjacent to the balloon or retracted from the balloon, or a shield can itself be inflatable, separately or together with the balloon.

Classes IPC  ?

95.

Endoscopic/percutaneous electronic radiation applicator and method of use

      
Numéro d'application 11481242
Numéro de brevet 07914434
Statut Délivré - en vigueur
Date de dépôt 2006-07-03
Date de la première publication 2008-01-03
Date d'octroi 2011-03-29
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s)
  • Francescatti, Darius
  • Lovoi, Paul A.

Abrégé

Treatment of lesions in any luminal or organ system of mammalian anatomy is performed using an electronic source of ionizing radiation and aided by an endoscopic or percutaneous approach.

Classes IPC  ?

96.

Gynecological instrument

      
Numéro d'application 11746983
Numéro de brevet 07871365
Statut Délivré - en vigueur
Date de dépôt 2007-05-10
Date de la première publication 2007-11-29
Date d'octroi 2011-01-18
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Van'T Hooft, Eric

Abrégé

An apparatus is described for irradiating cervical cancer, comprising multiple source guide tubes with a coupling piece situated outside the patient that connects the tubes outside the patient. The source guide tubes are formed such that the portions of the tubes situated in the patient upon insertion hook to each other so that the tubes are locked relative to each other. In an embodiment, the apparatus further comprises a central catheter tube to be guided into the uterus, which is provided with a flange-shaped stop for stabilizing the central tube relative to the uterus, the stop being formed for securing a position of the central tube relative to the further source guide tubes.

Classes IPC  ?

97.

Method for locating a source in a body

      
Numéro d'application 11744515
Numéro de brevet 08033980
Statut Délivré - en vigueur
Date de dépôt 2007-05-04
Date de la première publication 2007-11-22
Date d'octroi 2011-10-11
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Van'T Hooft, Eric

Abrégé

The invention relates to a source guide apparatus for guiding and locating a radiation source in a human body, wherein a catheter is provided in a body and connected to the apparatus, and wherein the proximal end is kept in a predetermined position with respect to the body. According to the invention, a treatment window is set, which is situated within the body, within which the source can be kept in respective positions, wherein the treatment window has a fixed window width and a reference position situated at a predetermined distance with respect to the proximal end of the catheter. The source guide apparatus guides the source through the catheter to a predetermined position in the body, measured relative to the treatment window.

Classes IPC  ?

98.

FLEXISHIELD

      
Numéro de série 77267570
Statut Enregistrée
Date de dépôt 2007-08-29
Date d'enregistrement 2008-05-13
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Classes de Nice  ? 10 - Appareils et instruments médicaux

Produits et services

RADIATION BARRIER TO BE PLACED AGAINST THE EXTERIOR OF A PATIENT FOR BRACHYTHERAPY PROCEDURES

99.

MicroSelectron

      
Numéro d'application 924299
Statut Enregistrée
Date de dépôt 2006-12-12
Date d'enregistrement 2006-12-12
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Classes de Nice  ?
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 37 - Services de construction; extraction minière; installation et réparation
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 42 - Services scientifiques, technologiques et industriels, recherche et conception

Produits et services

Scientific apparatus and instruments, including scientific apparatus and instruments in the field of cancer and brachytherapy, including image guided brachytherapy and adaptive brachytherapy; computer hardware and computer software in the medical field, including computer hardware and computer software for use in radio-oncology; brachytherapy treatment systems (being medical software or hardware) as well as medical computer software and apparatus for imaging and real time imaging; non medical electronic apparatus (as far as not included in other classes) for use in cancer therapy; x-ray brachytherapy apparatus (not for medical use) for scientific purposes. Medical apparatus and instruments, including medical apparatus and instruments in the field of cancer and brachytherapy, including image guided brachytherapy and adaptive brachytherapy, afterloaders, applicators, needles and templates, all for use in radio-oncology, cancer and brachytherapy treatment; medical apparatus for microsurgery interventions and applications; x-ray brachytherapy apparatus (for medical use); bioabsorbable materials for medical and surgical use, permanent implants (of artificial materials), medical disposables, nanomaterials and nanosources for medical use. Installation, maintenance and repair of computer hardware in the medical field. Education, training and organizing of congresses, workshops, courses, seminars and user meetings (also in-house) in the field of radiation therapy. Design, development, programming and updating of computer hardware and computer software in the medical field; installation, maintenance and repair of computer software in the medical field; scientific and technological services as well as accompanying research and design services.

100.

Method for identifying the location of at least one treatment channel that is one of a plurality of treatment channels, as well as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body

      
Numéro d'application 11187941
Numéro de brevet 08145290
Statut Délivré - en vigueur
Date de dépôt 2005-07-25
Date de la première publication 2007-04-05
Date d'octroi 2012-03-27
Propriétaire NUCLETRON OPERATIONS B.V. (Pays‑Bas)
Inventeur(s) Kindlein, Johann

Abrégé

The invention relates to a method for identifying the location at least one treatment channel from a group of a plurality of treatment channels as wells as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body. C comparing said reconstructed location said pre-planned plurality of locations. Furthermore the system according to the invention is characterized in that identifying means are present for identifying the location of at least one treatment channel from said group of said plurality of inserted treatment channels and comparing said identified location with one or more of said pre-planned locations present in said treatment plan.

Classes IPC  ?

  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
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