This document discusses, among other things, systems and methods to receive cardiac electrical information of a subject, detect a premature ventricular contraction (PVC) event in a first detection window using the received cardiac electrical information, determine a count of detected PVC events in the first detection window, remove cardiac electrical information associated with the detected PVC event from the first detection window based on the determined count of detected PVC events, and detect an indication of atrial fibrillation of the subject for the first detection window using remaining cardiac electrical information in the first detection window.
Systems and methods to enable secure remote programming of an implantable medical device are disclosed, including implementing a patient- specific RFID communication protocol using first and second portions of configurable memory of an RFID circuit, separate from a communication circuit of the implantable medical device, to provide an initialization key using the first portion of configurable memory of the RFID circuit and receive an authorization sequence from the remote device using the second portion of configurable memory of the RFID circuit, wherein the implantable medical device or the RFID circuit is configured transition a state of the implantable medical device or the communication circuit of the implantable medical device based on the received authorization sequence stored in the second portion of configurable memory of the RFID circuit.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p. ex. pour planifier la maintenance ou les mises à jour
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 90/90 - Moyens d’identification pour les patients ou les instruments, p. ex. étiquettes
3.
IMPLANTABLE CARDIAC DEVICE REMOTE RFID REPROGRAMMING SECURITY
Systems and methods to enable secure remote programming of an implantable medical device are disclosed, including implementing a patient-specific RFID communication protocol using first and second portions of configurable memory of an RFID circuit, separate from a communication circuit of the implantable medical device, to provide an initialization key using the first portion of configurable memory of the RFID circuit and receive an authorization sequence from the remote device using the second portion of configurable memory of the RFID circuit, wherein the implantable medical device or the RFID circuit is configured transition a state of the implantable medical device or the communication circuit of the implantable medical device based on the received authorization sequence stored in the second portion of configurable memory of the RFID circuit.
G06F 21/44 - Authentification de programme ou de dispositif
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
Systems and methods to improve programming of medical devices and delivery of cardiac pacing are disclosed, including receiving parameter settings of an ambulatory medical device, processing the received parameter settings by inputting the received parameter settings into one or more pre-trained machine learning models to identify one or more differences between the parameter settings of the ambulatory medical device and the model parameter settings of one or more other ambulatory medical devices, and generating a programming recommendation for the ambulatory medical device to improve cardiac capture for the patient based on the identified one or more differences.
A61N 1/365 - Stimulateurs cardiaques commandés par un paramètre physiologique, p. ex. par le potentiel cardiaque
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
Systems and methods to improve programming of medical devices and delivery of cardiac pacing are disclosed, including receiving parameter settings of an ambulatory medical device, processing the received parameter settings by inputting the received parameter settings into one or more pre-trained machine learning models to identify one or more differences between the parameter settings of the ambulatory medical device and the model parameter settings of one or more other ambulatory medical devices, and generating a programming recommendation for the ambulatory medical device to improve cardiac capture for the patient based on the identified one or more differences.
An implantable medical device may include each of a conductive canister, a printed circuit board assembly (PCBA), and a header. A feedthrough and ferrule couple the interior of the canister, where the PCBA is, to one or more elements contained in the header such as an antenna and/or a port for coupling to a lead. The ferrule may be directly attached to the conductive canister and the electronic circuit board. The electronic circuit board carries an RF transmitter for telemetry purposes, and has an RF ground plane layer therein. The ferrule is capacitively coupled to the RF ground plane the PCBA, and has a size and/or shape relative to the RF ground plane that provides sufficient capacitance to offer an improved RF ground plane path to the conductive canister at a desired telemetry frequency.
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
A61N 1/375 - Aménagements structurels, p. ex. boîtiers
H01Q 1/27 - Adaptation pour l'utilisation dans ou sur les corps mobiles
H04Q 9/00 - Dispositions dans les systèmes de commande à distance ou de télémétrie pour appeler sélectivement une sous-station à partir d'une station principale, sous-station dans laquelle un appareil recherché est choisi pour appliquer un signal de commande ou pour obtenir des valeurs mesurées
7.
CONTINUOUS UNIPOLAR IMPEDANCE MONITORING TO DIAGNOSE LEFT BUNDLE BRANCH AREA PACING LEAD STABILITY
A method of operating a cardiac rhythm management (CRM) system includes recurrently calculating, by a medical device of the CRM system, impedances between a housing electrode included in a housing of the medical device and each of multiple pacing electrodes, wherein the multiple pacing electrodes include a left bundle branch pacing electrode configured for placement in a left bundle branch of a subject; comparing the calculated impedances to one or more specified impedance values; and producing an alert regarding placement of a pacing electrode in response to a calculated impedance corresponding to the pacing electrode differing from the one or more specified impedance values by a predetermined threshold impedance value.
Systems and methods are disclosed to an ambulatory medical device including an inductive link, a radio frequency (RF) link, and a control circuit. The inductive link includes a coil antenna configured to receive a near field communication signal using mutual inductance. The RF link includes an RF antenna configured to receive an RF communication signal during a communication session. The control circuit is configured to decode an instruction received in the RF communication signal, wherein a class of the instruction requires the communication session to be started using the inductive link when performing the instruction; perform the instruction when the communication session is started using the inductive link and reject the instruction when the communication session is started using the RF link.
Systems and methods are disclosed. A device may include means for receiving physiologic information of a patient, including S4 heart sound information. A device may include an assessment means configured to: receive an indication of administered HCM therapy, determine a change in an HCM condition using the received S4 heart sound information by comparing S4 heart sound information over a first time period before the indication of administered HCM therapy with S4 heart sound information over a second time period subsequent to the indication of administered HCM therapy, provide an indication of HCM therapy efficacy to a user or process based on the determined change in HCM condition.
A method includes measuring baseline heart sounds using an ambulatory heart sound monitor, measuring baseline blood oxygen content using an ambulatory optical monitor, measuring new heart sounds, measuring new blood oxygen content, determining a relative increase in the new heart sounds compared to the baseline heart sounds, determining a relative decrease in the new blood oxygen content compared to the baseline blood oxygen content, and generating an alert in response to a combination of both the relative increase and the relative decrease.
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
A61B 5/1459 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale invasifs, p. ex. introduits dans le corps par un cathéter
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
Systems and methods are disclosed. A device may include a signal receiver circuit configured to receive physiologic information of a patient, including S4 heart sound information. A device may include an assessment circuit configured to: receive an indication of HCM for the patient, determine a change in an HCM condition using the received S4 heart sound information over a first time period, the first time period comprising multiple days, and provide an indication to a user or process based on the determined change in the HCM condition exceeding an alert threshold.
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
Systems and methods are disclosed to an ambulatory medical device including an inductive link, a radio frequency (RF) link, and a control circuit. The inductive link includes a coil antenna configured to receive a near field communication signal using mutual inductance. The RF link includes an RF antenna configured to receive an RF communication signal during a communication session. The control circuit is configured to decode an instruction received in the RF communication signal, wherein a class of the instruction requires the communication session to be started using the inductive link when performing the instruction; perform the instruction when the communication session is started using the inductive link and reject the instruction when the communication session is started using the RF link.
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
H04W 4/80 - Services utilisant la communication de courte portée, p. ex. la communication en champ proche, l'identification par radiofréquence ou la communication à faible consommation d’énergie
Systems and methods are disclosed. A device may include means for receiving physiologic information of a patient, including S4 heart sound information. A device may include an assessment means configured to: receive an indication of administered HCM therapy, determine a change in an HCM condition using the received S4 heart sound information by comparing S4 heart sound information over a first time period before the indication of administered HCM therapy with S4 heart sound information over a second time period subsequent to the indication of administered HCM therapy, provide an indication of HCM therapy efficacy to a user or process based on the determined change in HCM condition.
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
G16H 20/30 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies ou des activités physiques, p. ex. la physiothérapie, l’acupression ou les exercices
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
A method includes measuring baseline heart sounds using an ambulatory heart sound monitor, measuring baseline blood oxygen content using an ambulatory optical monitor, measuring new heart sounds, measuring new blood oxygen content, determining a relative increase in the new heart sounds compared to the baseline heart sounds, determining a relative decrease in the new blood oxygen content compared to the baseline blood oxygen content, and generating an alert in response to a combination of both the relative increase and the relative decrease.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
Systems and methods to improve patient monitoring and device operation during a near-implant time period are disclosed, including determining a representative value of physiologic information of a patient sensed in a near-implant time period after implant of an implantable medical device in the patient, determining an absolute or hybrid baseline corresponding to the near-implant time period using information from at least one of an imputed baseline corresponding to a pre-implant time period preceding implant of the implantable medical device in the patient or an initial value of the received physiologic information of the patient in an initial portion of the near-implant time period, and determining an indication of patient condition as a function of the determined representative value and the determined absolute or hybrid baseline.
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A method includes detecting that a first premature ventricular contraction (PVC) episode occurred within a first length of electrocardiogram (ECG) data. The method further includes recording the first length of ECG data to memory in response to the detecting. A second PVC episode is determined to have occurred after the first PVC episode and within a second length of ECG data, and the second PVC episode is determined to be either a first type of PVC episode or a second type of PVC episode. The method further includes determining whether to either overwrite the first length of ECG data or to separately record the second length of ECG data to the memory based, at least in part, on the determining that the second PVC episode is the first type of PVC episode or the second type of PVC episode.
A61B 5/333 - Appareils d’enregistrement spécialement adaptés à cet effet
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
A61B 5/287 - Supports pour électrodes multiples, p. ex. cathéters à électrode pour des études électrophysiologiques [EEP]
Systems and methods to improve patient monitoring and device operation during a near-implant time period are disclosed, including determining a representative value of received physiologic information of a patient sensed by an implantable medical device implanted in the patient, determining a hybrid or relative baseline for the patient using the received physiologic information, and determining an indication of patient condition as a weighted function of (1) the representative value of the received physiologic information, (2) an absolute baseline, and (3) the hybrid or relative determined relative baseline, with a weight of at least one the determined absolute baseline or the determined relative baseline changing with time relative to a time of implant of the implantable medical device.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
A method includes detecting that a first premature ventricular contraction (PVC) episode occurred within a first length of electrocardiogram (ECG) data. The method further includes recording the first length of ECG data to memory in response to the detecting. A second PVC episode is determined to have occurred after the first PVC episode and within a second length of ECG data, and the second PVC episode is determined to be either a first type of PVC episode or a second type of PVC episode. The method further includes determining whether to either overwrite the first length of ECG data or to separately record the second length of ECG data to the memory based, at least in part, on the determining that the second PVC episode is the first type of PVC episode or the second type of PVC episode.
Systems and methods to improve patient monitoring and device operation during a near-implant time period are disclosed, including determining a representative value of received physiologic information of a patient sensed by an implantable medical device implanted in the patient, determining a hybrid or relative baseline for the patient using the received physiologic information, and determining an indication of patient condition as a weighted function of (1) the representative value of the received physiologic information, (2) an absolute baseline, and (3) the hybrid or relative determined relative baseline, with a weight of at least one the determined absolute baseline or the determined relative baseline changing with time relative to a time of implant of the implantable medical device.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
Systems and methods to improve patient monitoring and device operation during a near-implant time period are disclosed, including determining a representative value of physiologic information of a patient sensed in a near-implant time period after implant of an implantable medical device in the patient, determining an absolute or hybrid baseline corresponding to the near-implant time period using information from at least one of an imputed baseline corresponding to a pre-implant time period preceding implant of the implantable medical device in the patient or an initial value of the received physiologic information of the patient in an initial portion of the near-implant time period, and determining an indication of patient condition as a function of the determined representative value and the determined absolute or hybrid baseline.
Systems and methods for monitoring patients with multiple chronic diseases are described. A system may include a health status monitor that receives diagnostic data including physiological signals sensed from a patient. The system may produce at least a first risk indication of the patient developing a first disease and a second risk indication of the patient developing a different second disease. The system may detect the first and second diseases from the physiological signals, and generate a composite health status indicator using the detections of the first and second diseases and the first and second risk indications. An alert of worsening health status may be generated if the composite detection score exceeds an alert threshold.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
22.
IMD ENCLOSURE FORMED USING DIELECTRIC MATERIALS INCORPORATING FEEDTHRU(S)
Embodiments of the present disclosure relate to implantable medical device (IMD) enclosures. In an exemplary embodiment, an IMD comprises: a housing comprising an open end and a header defining a cavity and comprising at least one conduit through a wall of the header, wherein the header is formed from a non-conductive material. Further, the IMD comprises a coupling member comprising a flange, wherein the flange is configured to be received by the open end of the housing and wherein the flange and the open end of the housing at least partially overlap along an axial direction of the IMD when the flange is received by the open end. Additionally, the IMD comprises an electrode arranged on an outer surface of the header and a feedthrough coupled to the electrode and extending through the conduit of the header, wherein the feedthrough is configured to be coupled to internal circuity housed within the IMD. Further, the IMD comprises a ring forming a hermetic seal between the coupling member and the header.
Systems, methods, and devices involve receiving a package of data that includes an electrocardiogram (ECG) waveform associated with a potential cardiac event, processing the ECG waveform to extract interval data associated with the potential cardiac event, inputting the ECG waveform and the interval data into a trained machine learning model, and determining, by the trained machine learning model, that the potential cardiac event comprises a normal rhythm.
A61B 5/352 - Détection des crêtes de l'onde R, p. ex. pour la synchronisation d'appareils de diagnosticEstimation de l’intervalle entre crêtes R
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/339 - Affichages spécialement adaptés à cet effet
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
An implantable lead for use with an implantable medical device (IMD) includes a tubular lead body having proximal end and a distal end opposite the proximal end. A proximal connector is located at the proximal end of the lead body and is configured for mechanically and electrically coupling the lead to the IMD. The lead includes a pre-formed distal portion having a first portion extending from the distal end to a first curve. The first portion is located in a first plane. A second portion extends from the first curve to a second curve, wherein the second portion and the second curve are located in a second plane that is generally orthogonal to the first plane. A helical electrode extends distally from the distal end of the tubular lead body and a ring electrode is located along the first portion.
An implantable lead for use with an implantable medical device (IMD) includes a tubular lead body having proximal end and a distal end opposite the proximal end. A proximal connector is located at the proximal end of the lead body and is configured for mechanically and electrically coupling the lead to the IMD. The lead includes a pre-formed distal portion having a first portion extending from the distal end to a first curve. The first portion is located in a first plane. A second portion extends from the first curve to a second curve, wherein the second portion and the second curve are located in a second plane that is generally orthogonal to the first plane. A helical electrode extends distally from the distal end of the tubular lead body and a ring electrode is located along the first portion.
A connector port assembly for releasably securing an implantable lead to a header of an implantable medical device comprises a connector block having a connector block bore and an access hole extending radially through the connector block and oriented orthogonally to an axis of the connector block bore and sized to receive a shaft of a release tool, and a collet assembly including a collet body and a plurality of bearings arranged about a circumference of the collet body, the collet body including a forward end portion having a curved outer surface, and a distal portion opposite the forward end portion, wherein the access hole of the connector block is positioned such that a shaft of the release tool can engage the curved outer surface of the forward end portion of the collet body.
Systems and methods are disclosed to a medical device system comprising a cardiac signal sensing circuit, a heart sound sensor, a signal processing circuit, and a control circuit. The cardiac signal sensing circuit produces a sensed cardiac signal representative of cardiac depolarization signals when connected to electrodes. The heart sound sensor produces a sensed heart sound signal representative of vibrational sounds of the heart. The signal processing circuit identifies premature ventricular contractions (PVCs) using sensed cardiac signal information. The control circuit is configured to calculate a PVC burden of the patient using PVC information, determine that the calculated PVC burden exceeds a threshold PVC burden and that the patient is asymptomatic for heart failure, determine that sensed heart sound signal information indicates heart failure of the patient, and present a recommendation of an echocardiogram for the patient to a user.
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
28.
PHYSIOLOGIC SENSORS TO AUGMENT PVC BURDEN INFORMATION
Systems and methods are disclosed to a medical device system comprising a cardiac signal sensing circuit, a heart sound sensor, a signal processing circuit, and a control circuit. The cardiac signal sensing circuit produces a sensed cardiac signal representative of cardiac depolarization signals when connected to electrodes. The heart sound sensor produces a sensed heart sound signal representative of vibrational sounds of the heart. The signal processing circuit identifies premature ventricular contractions (PVCs) using sensed cardiac signal information. The control circuit is configured to calculate a PVC burden of the patient using PVC information, determine that the calculated PVC burden exceeds a threshold PVC burden and that the patient is asymptomatic for heart failure, determine that sensed heart sound signal information indicates heart failure of the patient, and present a recommendation of an echocardiogram for the patient to a user.
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/332 - Dispositifs portables spécialement adaptés à cet effet
Systems and methods for monitoring heart failure (HF) status in a patient are discussed. An exemplary system includes a gait analyzer circuit than can receive gait or balance information, and generate a gait feature such as gait speed or a gait pattern. The system includes a HF detector circuit that can detect patient HF status, or to predict patient risk of a future worsening heart failure (WHF) event, using the gait feature. In some examples, the system may trigger sensing physiologic information according to the detected gait, and detect patient HF status using the sensed physiologic information. The system can initiate or adjust a heart failure therapy according to the HF status or the WHF risk.
A system and method for optimizing arrhythmia detection in an ambulatory medical device is provided. Physiological signal data obtained by the medical device is analyzed using one or more machine learning models trained to detect different arrhythmia types. When an arrhythmia episode is detected in the analyzed physiological data that was missed by the device's own detection algorithms, the system automatically generates a recommendation to adjust the device's detection parameters, such as by increasing detection sensitivity, to improve future performance. Periodically re-evaluating collected physiological data with advanced machine learning techniques in this manner enables closed-loop optimization of the device's arrhythmia detection overtime. This enhances the accuracy of arrhythmia diagnosis compared to relying solely on the device's static detection settings.
A61B 5/363 - Détection de la tachycardie ou de la bradycardie
G16H 40/60 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux
Systems and methods are disclosed to determine or adjust a health index for a patient, including receiving physiologic information of the patient, receiving chemical information of the patient, determining a composite health index for the patient as a weighted function of one or more physiologic features of the received physiologic information and one or more chemical features of the received chemical information, and generating a composite health index alert as a function of the determined composite health index and an alert threshold.
A system and method for optimizing arrhythmia detection in an ambulatory medical device is provided. Physiological signal data obtained by the medical device is analyzed using one or more machine learning models trained to detect different arrhythmia types. When an arrhythmia episode is detected in the analyzed physiological data that was missed by the device's own detection algorithms, the system automatically generates a recommendation to adjust the device's detection parameters, such as by increasing detection sensitivity, to improve future performance. Periodically re-evaluating collected physiological data with advanced machine learning techniques in this manner enables closed-loop optimization of the device's arrhythmia detection over time. This enhances the accuracy of arrhythmia diagnosis compared to relying solely on the device's static detection settings.
A61B 5/33 - Modalités électriques se rapportant au cœur, p. ex. électrocardiographie [ECG] spécialement adaptées à l’utilisation conjointe avec d’autres dispositifs
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/352 - Détection des crêtes de l'onde R, p. ex. pour la synchronisation d'appareils de diagnosticEstimation de l’intervalle entre crêtes R
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
33.
CHEMICAL INFORMATION BASED ALERT STATE DETERMINATION
Systems and methods are disclosed to determine an alert state for a health index using the health index and one or more pieces of chemical information. The chemical information can include potassium level, creatinine level, etc. The determined alert state can be provided to a user or a process.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
Systems and methods are disclosed to trigger a diuresis monitoring window, including determining a health index for a patient as a function of received physiologic information, determining a health index alert state for the patient using a value of the determined health index and a health index alert threshold, monitoring the health index in the health index alert state, triggering, in response to a detected change in the health index in the health index alert state indicating an improved patient condition, a start of the diuresis monitoring window, receiving chemical information of the patient during the diuresis monitoring window, and monitoring a chemical parameter of the patient during the diuresis monitoring window using the received chemical information.
Systems and methods are disclosed to trigger a diuresis monitoring window, including determining a health index for a patient as a function of received physiologic information, determining a health index alert state for the patient using a value of the determined health index and a health index alert threshold, monitoring the health index in the health index alert state, triggering, in response to a detected change in the health index in the health index alert state indicating an improved patient condition, a start of the diuresis monitoring window, receiving chemical information of the patient during the diuresis monitoring window, and monitoring a chemical parameter of the patient during the diuresis monitoring window using the received chemical information.
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
36.
CHEMICAL INFORMATION BASED ALERT STATE DETERMINATION
Systems and methods are disclosed to determine an alert state for a health index using the health index and one or more pieces of chemical information. The chemical information can include potassium level, creatinine level, etc. The determined alert state can be provided to a user or a process.
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
Systems and methods are disclosed to determine or adjust a health index for a patient, including receiving physiologic information of the patient, receiving chemical information of the patient, determining a composite health index for the patient as a weighted function of one or more physiologic features of the received physiologic information and one or more chemical features of the received chemical information, and generating a composite health index alert as a function of the determined composite health index and an alert threshold.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
Systems and methods for recognizing and tracking heart sound components are disclosed. An exemplary medical-device system includes a data receiver to receive heart sound information, and a heart sound recognition circuit to generate a representative heart sound segment such as an ensemble average of a selected portion of heart sound segments. The heart sound recognition circuit recognizes a heart sound component from the representative heart sound segment using a time-based tracking algorithm, and evaluates a performance index of the time-based heart sound tracking algorithm. Based on the performance index, a decision can be made whether or not to switch to a spectral-based tracking algorithm to recognize the heart sound component from the representative heart sound segment. A physiologic event detector can detect a cardiac event using the recognized heart sound component.
A system includes a medical device that is implantable. The medical device includes circuitry for processing physiological data, a battery that is rechargeable and that is electrically coupled to the circuitry to provide power to the circuitry, a charge coil arranged to generate current responsive to externally-generated magnetic fields and electrically coupled to the battery to charge the battery, and a magnetic field guide arranged to guide the externally-generated magnetic fields towards the charge coil.
Systems and methods for recognizing and tracking heart sound components are disclosed. An exemplary medical-device system includes a data receiver to receive heart sound information, and a heart sound recognition circuit to generate a representative heart sound segment such as an ensemble average of a selected portion of heart sound segments. The heart sound recognition circuit recognizes a heart sound component from the representative heart sound segment using a time-based tracking algorithm, and evaluates a performance index of the time-based heart sound tracking algorithm. Based on the performance index, a decision can be made whether or not to switch to a spectral-based tracking algorithm to recognize the heart sound component from the representative heart sound segment. A physiologic event detector can detect a cardiac event using the recognized heart sound component.
Systems, methods, and devices feature a wearable device that includes a set of needles sized for access to interstitial fluid. The wearable device also includes a chemical indicator associated with each needle. A concentration of an analyte within the interstitial fluid can be determined based on one or more optical properties of the chemical indicator.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/1473 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques invasifs, p. ex. introduits dans le corps par un cathéter
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
Systems, methods, and devices feature a wearable device that includes a set of needles sized for access to interstitial fluid. The wearable device also includes a chemical indicator associated with each needle. A concentration of an analyte within the interstitial fluid can be determined based on one or more optical properties of the chemical indicator.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/01 - Mesure de la température de parties du corps
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
A61B 5/1468 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques
43.
BIOMARKER FOR PULMONARY HYPERTENSION DETECTION IN HEART FAILURE
Systems and methods are disclosed to an ambulatory medical device. The ambulatory medical device comprising an activity sensor configured to produce an activity signal representative of activity level of a patient, a heart sound sensor configured to produce a heart sound signal, and a control circuit. The control circuit is configured to detect a change in activity level of the patient using the activity signal, enable monitoring of the heart sound signal in response to detecting the change in activity level, measure intensity of an S3 heart sound in the heart sound signal, and produce an indication of pulmonary hypertension (PH) when the measured intensity of the S3 heart sound exceeds a PH detection threshold intensity.
Systems and methods are disclosed to an ambulatory medical device comprising a coil antenna, a transceiver circuit, and a control circuit. The transceiver circuit includes a receiver to detect a communication signal received by the coil antenna. The control circuit includes a timeout timer and is configured to set the receiver to an active mode, set the receiver to an inactive mode when the timeout timer expires after a first timeout duration and the communication signal is not detected by the receiver, maintain the receiver in the active mode when the communication signal is detected by the receiver before the timeout timer expires, decode a command in the communication signal to set the timeout timer to a second timeout duration, and set the receiver to the inactive mode when the timeout timer expires after the second timeout duration and the communication signal is not detected.
H04B 5/73 - Systèmes de transmission en champ proche, p. ex. systèmes à transmission capacitive ou inductive spécialement adaptés à des fins spécifiques pour la prise de mesures, p. ex. en utilisant des bobines de détection
A method of constructing a capacitor can include forming a sintered electrode by sintering electrode material onto a portion of a first side of a substrate; and excising the sintered portion from the substrate by cutting through the substrate around a periphery of the sintered portion, without cutting the sintered portion, wherein excising includes using a femtosecond laser to cut through the substrate.
H01G 9/00 - Condensateurs électrolytiques, redresseurs électrolytiques, détecteurs électrolytiques, dispositifs de commutation électrolytiques, dispositifs électrolytiques photosensibles ou sensibles à la températureProcédés pour leur fabrication
A method includes detecting, using a medical device, a cardiac event based on a comparison of physiological data collected by the medical device to one or more programmed parameters of the medical device. The method further includes detecting, using the medical device, subevents associated with the cardiac event. The method further includes generating, using the medical device, metadata associated with the cardiac event and creating, using a computing system, a timeline of the cardiac event for display. The timeline includes icons associated with the subevents and including at least some of the metadata.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Software for an electrophysiology navigation and ablation system, namely, software that displays ablation locations filtered by location and ablation parameters featuring embedded identification tags.
Systems and methods are disclosed to optimize resources of a medical device system, including to analyze physiologic information of a patient occurring over specific time periods relative to a prior heart failure event, to adjust, in response to a detected or received trigger event, a baseline value for the patient from a long-term baseline value to one of a shorter-term baseline value or a static value indicative of a baseline value at a prior time relative to the detected or received trigger event, to determine a readmission score for the patient based on the analyzed physiologic information, and to provide a control signal to control a mode or operation of the medical device system based on the readmission score to optimize resources of the medical device system.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
Systems and methods are disclosed to optimize resources of a medical device system, including to analyze physiologic information of a patient occurring over specific time periods relative to a prior heart failure event, to adjust, in response to a detected or received trigger event, a baseline value for the patient from a long-term baseline value to one of a shorter-term baseline value or a static value indicative of a baseline value at a prior time relative to the detected or received trigger event, to determine a readmission score for the patient based on the analyzed physiologic information, and to provide a control signal to control a mode or operation of the medical device system based on the readmission score to optimize resources of the medical device system.
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 40/00 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux
G16H 50/00 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies
09 - Appareils et instruments scientifiques et électriques
Produits et services
Software for an electrophysiology navigation and ablation system, namely, software that displays ablation locations filtered by location and ablation parameters featuring embedded identification tags.
A medical device system includes an ambulatory medical device and a second device. The ambulatory medical device includes one or more physiologic sensors configured to output sensor data and a communication circuit to transmit the sensor data to another device. The second device includes another communication circuit configured to receive the sensor data from ambulatory medical device, and processing circuitry. The processing circuitry is configured to determine patterns of the sensor data consistent with hemodialysis treatments of the patient, identify a change in the patterns of the sensor data indicative of a change in the hemodialysis treatments, and produce an alert associated with the hemodialysis treatments in response to the determining the change in the patterns of the sensor data.
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
52.
CONDUCTION SYSTEM PACING LEADS AND METHODS OF MANUFACTURING (SNAP-FIT)
An implantable lead includes a tubular lead body having proximal end, a distal end opposite the proximal end. A distal assembly includes an outer shell having a proximal shell component and a distal shell component. A coupler is disposed within the outer shell and includes a proximal portion having a proximal end and a first channel extending distally from the proximal end, and a distal portion opposite the proximal portion. The proximal shell component is mechanically coupled to the proximal portion of the coupler by a first snap-fit connection, and the distal shell component is mechanically coupled to the proximal portion of the coupler by a second snap-fit connection. A helical electrode is disposed about the distal portion of the coupler, and extends distally from the distal portion of the shell. First and second electrical conductors extend through the lead body and are coupled to the coupler.
An implantable lead includes a tubular lead body having proximal end, a distal end opposite the proximal end. A distal assembly includes an outer shell having a proximal portion and a distal portion. A tubular inner preform is disposed at least partially within the outer shell and includes a longitudinal slot extending from the distal end toward the proximal end, and a circumferential slot extending partially around a circumference of the inner preform. A coupler is disposed within the shell and includes a channel extending distally from the proximal end and an intermediate portion between the proximal and distal portions. The inner preform is coupled to the proximal portion of the coupler. A helical electrode is disposed about the distal portion of the coupler and a distal portion extends from the distal portion of the shell. A first conductor is mechanically and electrically coupled to the coupler.
An implantable lead includes a distal assembly having an outer shell having a proximal portion and a distal portion. A tubular inner preform may be disposed at least partially within the outer shell and includes a proximal end, a distal end opposite the proximal end, a longitudinal slot extending from the distal end toward the proximal end, and a circumferential slot extending partially around a circumference of the inner preform. A coupler made of an electrically conductive material is disposed within the shell and includes a longitudinal channel. The inner preform is mechanically coupled to the coupler. In embodiments, the shell may be snap fit to the coupler. A helical electrode having a proximal portion is disposed about the distal portion of the coupler, and a distal portion extends distally from the distal portion of the shell.
A tool for implanting a medical lead includes a body having distal region including a distal end, a proximal region including a proximal end, a central axis extending from the distal end to the proximal end, and a midpoint between the distal end and the proximal end. The distal region includes a rounded tip, and a distal lip surrounding a distal opening leading to a distal cavity dimensioned to receive and frictionally engage a connector component of the implantable lead. The proximal region includes a proximal lip surrounding a proximal opening leading to a proximal cavity. A chamber is located between the distal cavity and the proximal cavity. The tool includes a first window. A pair of resilient arms define at least a portion of the chamber and configured to frictionally engage a terminal pin of the implantable lead. The first window, chamber, and pair of resilient arms are located distal of the midpoint.
A battery can include an anode and a cathode enclosed within a battery housing, a feedthrough terminal coupled to one of the anode or the cathode and extending through a lid of the battery housing, and a glass insulator between the feedthrough terminal and the lid, wherein an outside surface of the lid and an outer surface of the feedthrough terminal and an outer surface of the glass insulator is covered by a first layer of an electrically insulative coating.
Embodiments herein relate to implantable chemical sensors. In an embodiment, an implantable optical chemical sensor includes a circuit board, at least one optical emitter, and at least one optical detector. The optical emitter can be disposed on the circuit board along with the optical detector. The optical chemical sensor can also include a floor plate and a well plate, the well plate defining at least one well and the well plate disposed over the floor plate. The well plate can include a vertical facet and a beveled facet disposed on a perimeter edge of the well plate. A feed-through flange can define a window with the vertical facet of the well plate fitting into the window. The optical emitter can emit light through the floor plate and into the well plate which is then redirected by the beveled facet into the well. Other embodiments are also included herein.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/1459 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale invasifs, p. ex. introduits dans le corps par un cathéter
A61B 5/1473 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques invasifs, p. ex. introduits dans le corps par un cathéter
58.
OPTO-ELECTRONIC HARDWARE CONFIGURATIONS FOR IMPLANTABLE CHEMICAL SENSORS
Embodiments herein relate to implantable chemical sensors. In an embodiment, an implantable optical chemical sensor includes a circuit board, at least one optical emitter, and at least one optical detector. The optical emitter can be disposed on the circuit board along with the optical detector. The optical chemical sensor can also include a floor plate and a well plate, the well plate defining at least one well and the well plate disposed over the floor plate. The well plate can include a vertical facet and a beveled facet disposed on a perimeter edge of the well plate. A feed-through flange can define a window with the vertical facet of the well plate fitting into the window. The optical emitter can emit light through the floor plate and into the well plate which is then redirected by the beveled facet into the well. Other embodiments are also included herein.
A61B 5/1459 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale invasifs, p. ex. introduits dans le corps par un cathéter
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
59.
DELIVERY DEVICES AND METHODS FOR LEADLESS CARDIAC DEVICES
Delivery devices, systems, and methods for delivering implantable leadless pacing devices are disclosed. An example delivery device may include a proximal section including a deflection mechanism for deflecting the proximal section, and a distal holding section extending distally of a distal end of the proximal section and defining a cavity therein for receiving an implantable leadless pacing device. The distal holding section may be structured to have portions that flex and bend while allowing the implantable device to be recaptured within the distal holding section.
An implantable medical device (IMD) that includes a first light emitter arranged to generate a first beam of emitted light, a second light emitter arranged to generate a second beam of emitted light, a light detector arranged to sense backscattered light, and at least one optical layer comprising a beam steering feature and/or a cross-talk feature.
A61B 5/1459 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale invasifs, p. ex. introduits dans le corps par un cathéter
An implantable medical device (IMD) that includes a first light emitter arranged to generate a first beam of emitted light, a second light emitter arranged to generate a second beam of emitted light, a light detector arranged to sense backscattered light, and at least one optical layer comprising a beam steering feature and/or a cross-talk feature.
A method includes storing, by one or more servers, separate packages of data received from separate medical devices. The separate packages of data are respectively associated with different patients. The method includes automatically determining which subset of the patients experiences the most health events among the different patients. Access to the packages of data is provided via a user interface, and an indicator is displayed on the user interface showing which of the patients is associated with the subset. A computing system such as a server can be programmed to carry out one or more steps of the method.
G16H 40/60 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux
Systems and methods for verifying cardiac pause episodes detected by a medical device are disclosed. A medical -device system comprises a physiological event detector to receive information about a cardiac pause episode detected by a medical device from a patient using a device-based, detection algorithm. The physiological event detector uses an algorithm different from the device-based, detection algorithm to generate one or more metrics including at least one entropy metric from the received information about the cardiac pause episode, and verify a presence or absence of cardiac pause in the device-detected cardiac pause episode using such metrics. The verified presence or absence of the cardiac pause may be presented to a user or a process to determine a. medical condition, such as a risk of syncope in the patient.
A61B 5/29 - Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électrocardiographie [ECG] invasives pour implantation permanente ou à long terme
A61B 5/352 - Détection des crêtes de l'onde R, p. ex. pour la synchronisation d'appareils de diagnosticEstimation de l’intervalle entre crêtes R
A61B 5/364 - Détection d'intervalle ECG anormal, p. ex. des extrasystoles ou des battements cardiaques ectopiques
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
Systems and methods for verifying cardiac pause episodes detected by a medical device are disclosed. A medical-device system comprises a physiological event detector to receive information about a cardiac pause episode detected by a medical device from a patient using a device-based detection algorithm. The physiological event detector uses an algorithm different from the device-based detection algorithm to generate one or more metrics including at least one entropy metric from the received information about the cardiac pause episode, and verify a presence or absence of cardiac pause in the device-detected cardiac pause episode using such metrics. The verified presence or absence of the cardiac pause may be presented to a user or a process to determine a medical condition, such as a risk of syncope in the patient.
A61B 5/352 - Détection des crêtes de l'onde R, p. ex. pour la synchronisation d'appareils de diagnosticEstimation de l’intervalle entre crêtes R
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/339 - Affichages spécialement adaptés à cet effet
A61B 5/364 - Détection d'intervalle ECG anormal, p. ex. des extrasystoles ou des battements cardiaques ectopiques
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
An implantable medical device (IMD) is configured with a pressure sensor. The IMD includes a housing and a diaphragm that is exposed to the environment outside of the housing. The diaphragm is configured to transmit a pressure from the environment outside of the housing to a piezoelectric membrane. In response, the piezoelectric membrane generates a voltage and/or a current, which is representative of a pressure change applied to the housing diaphragm. In some cases, only changes in pressure over time are used, not absolute or gauge pressures.
A61N 1/365 - Stimulateurs cardiaques commandés par un paramètre physiologique, p. ex. par le potentiel cardiaque
A61N 1/368 - Stimulateurs cardiaques commandés par un paramètre physiologique, p. ex. par le potentiel cardiaque comprenant plus d'une électrode coopérant avec différentes régions du cœur
Systems and methods are disclosed to determine and record one or more key metrics of atrial fibrillation for a patient, including determining indications of atrial fibrillation of the patient in respective detection windows of a day using received physiologic information, recording first physiologic information of the patient at a first sampling frequency for the determined indications of atrial fibrillation of the patient up to and not exceeding a first threshold of the medical device system for transmission to a remote device, and determining and recording one or more key metrics of atrial fibrillation for the determined indications of atrial fibrillation of the patient at a second sampling frequency lower than the first sampling frequency without regard to the first threshold.
Systems and methods are disclosed to determine and record one or more key metrics of atrial fibrillation for a patient, including determining indications of atrial fibrillation of the patient in respective detection windows of a day using received physiologic information, recording first physiologic information of the patient at a first sampling frequency for the determined indications of atrial fibrillation of the patient up to and not exceeding a first threshold of the medical device system for transmission to a remote device, and determining and recording one or more key metrics of atrial fibrillation for the determined indications of atrial fibrillation of the patient at a. second sampling frequency lower than the first sampling frequency without regard to the first threshold.
An ambulatory medical device includes a multi-axis posture sensor and processing circuitry. The multi -axis posture sensor is configured to provide an electrical posture sensor output representative of alignment of respective first, second, and third non-parallel axes of the ambulatory medical device with the gravitational field of the earth. The processing circuitry is configured to determine that the subject avoids lying on their left side using the posture sensor output, and compute a metric predictive of one or both of orthopnea and trepopnea in response to determining that the subject avoids lying on their left side.
Systems and methods are disclosed to an ambulatory medical device comprising a cardiac signal sensing circuit configured to sense a cardiac signal representative of cardiac activity of a patient when connected to electrodes, and a control circuit. The control circuit is configured to monitor cardiac depolarizations in the sensed cardiac signal, detect a bimodal distribution of heart rate of the patient, identify cardiac depolarization intervals shorter than a predetermined interval threshold, identify premature atrial contractions (PACs) in the sensed cardiac signal that are conducted normally and conducted aberrantly, and count a number of conducted PACs and produce an alert related to PC burden of the patient based on the number.
Systems and methods are disclosed to apply, in response to a detected atrial sense event in a first cardiac cycle, a ventricular blanking period for the first cardiac cycle and to detect a ventricular sense event in the first cardiac cycle using the received electrical information following the determined ventricular blanking period.
A61N 1/365 - Stimulateurs cardiaques commandés par un paramètre physiologique, p. ex. par le potentiel cardiaque
A61N 1/368 - Stimulateurs cardiaques commandés par un paramètre physiologique, p. ex. par le potentiel cardiaque comprenant plus d'une électrode coopérant avec différentes régions du cœur
71.
SYSTEM FOR PREMATURE ATRIAL CONTRACTION BURDEN ESTIMATION
Systems and methods are disclosed to an ambulatory medical device comprising a cardiac signal sensing circuit configured to sense a cardiac signal representative of cardiac activity of a patient when connected to electrodes, and a control circuit. The control circuit is configured to monitor cardiac depolarizations in the sensed cardiac signal, detect a bimodal distribution of heart rate of the patient, identify cardiac depolarization intervals shorter than a predetermined interval threshold, identify premature atrial contractions (PACs) in the sensed cardiac signal that are conducted normally and conducted aberrantly, and count a number of conducted PACs and produce an alert related to PC burden of the patient based on the number.
An ambulatory medical device includes a multi-axis posture sensor and processing circuitry. The multi-axis posture sensor is configured to provide an electrical posture sensor output representative of alignment of respective first, second, and third non-parallel axes of the ambulatory medical device with the gravitational field of the earth. The processing circuitry is configured to determine that the subject avoids lying on their left side using the posture sensor output, and compute a metric predictive of one or both of orthopnea and trepopnea in response to determining that the subject avoids lying on their left side.
Systems, devices and methods for determining sensing quality changes and drops in an implantable medical device, remotely and/or within the device itself. A cardiac implantable medical device tracks, over time, a number of counters, the contents of which are communicated to a processor which may be part of a remote monitoring device or which may be a customer service center that receives data from remote monitoring devices and/or programmers. Counter data is analyzed to identify changes in sensing quality and/or to provide information useful for clinical investigations, system integrity checking, or device reprogramming.
Systems, devices and methods for determining sensing quality changes and drops in an implantable medical device, remotely and/or within the device itself. A cardiac implantable medical device tracks, over time, a number of counters, the contents of which are communicated to a processor which may be part of a remote monitoring device or which may be a customer service center that receives data from remote monitoring devices and/or programmers. Counter data is analyzed to identify changes in sensing quality and/or to provide information useful for clinical investigations, system integrity checking, or device reprogramming.
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p. ex. pour planifier la maintenance ou les mises à jour
Systems, methods, and devices involve approaches for limiting the number of detected cardiac events for which a physician is alerted. Approaches involve detecting cardiac events based on electrocardiogram (ECG) data and associating the cardiac events with a criticality. ECG data associated with a subset of the cardiac events is transmitted to a remote computing system based, at least in part, on the criticality. An electronic notification is transmitted to a patient care group regarding at least one of the cardiac events in the subset. Approaches further include determining whether an acknowledgement of the electronic notification has been received by the server from the patient care group within a set period of time.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/318 - Modalités électriques se rapportant au cœur, p. ex. électrocardiographie [ECG]
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p. ex. leur création ou leur transmission
76.
ST ELEVATED MYOCARDIAL INFARCTION (STEMI) DETECTION IN INSERTABLE CARDIAC MONITOR
Systems and methods are disclosed to signal processing device of a patient management system. The signal processing device comprising a communication circuit configured to receive a cardiac signal from an AMD, wherein the received cardiac signal is a frequency filtered cardiac signal produced from a broader frequency band cardiac signal sensed using the AMD; signal processing circuitry configured to restore the received cardiac signal to the broader frequency band cardiac signal; detect an elevated ST segment in the restored broader frequency band cardiac signal; and generate an alert of myocardial infarction in response to detecting the elevated ST segment.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/287 - Supports pour électrodes multiples, p. ex. cathéters à électrode pour des études électrophysiologiques [EEP]
A61B 5/29 - Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électrocardiographie [ECG] invasives pour implantation permanente ou à long terme
77.
INSERTABLE CARDIAC MONITOR WITH MYOCARDIAL INFARCTION DETECTION
Systems and methods are disclosed to signal processing device of a patient management system. The signal processing device comprising a communication circuit configured to receive a cardiac signal from an AMD, wherein the received cardiac signal is a frequency filtered cardiac signal produced from a broader frequency band cardiac signal sensed using the AMD; signal processing circuitry configured to restore the received cardiac signal to the broader frequency band cardiac signal; detect an elevated ST segment in the restored broader frequency band cardiac signal; and generate an alert of myocardial infarction in response to detecting the elevated ST segment.
Systems, methods, and devices involve approaches for limiting the number of detected cardiac events for which a physician is alerted. Approaches involve detecting cardiac events based on electrocardiogram (ECG) data and associating the cardiac events with a criticality. ECG data associated with a subset of the cardiac events is transmitted to a remote computing system based, at least in part, on the criticality. An electronic notification is transmitted to a patient care group regarding at least one of the cardiac events in the subset. Approaches further include determining whether an acknowledgement of the electronic notification has been received by the server from the patient care group within a set period of time.
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p. ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
79.
SLEEP DETECTION USING CARDIAC AND RESPIRATION INFORMATION
Systems and methods for monitoring and staging sleep using cardiac and respiration information are disclosed. An exemplary system comprises a storage device to store a trained hybrid sleep detection and classification model that comprise a plurality of trained machine-learning models each trained to map input cardiac and respiratory data into one of multiple distinct model-specific awake or sleep classes, and a trained regression model to combine the model- specific awake or sleep classes to a composite awake or sleep classification. A sleep detector applies patient cardiac and respiratory information to the trained hybrid sleep detection and classification model to determine a composite awake or sleep classification for the patient. The composite awake or sleep classification is used to diagnose medical conditions including sleep apnea.
A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
80.
AORTIC STENOSIS SEVERITY QUANTIFICATION USING HEART SOUNDS
Systems and methods for monitoring and managing aortic stenosis are disclosed. An exemplary medical-device system comprises a data receiver to receive heart sound information sensed by ambulatory heart sound sensors, and a stenosis detector to detect a change in aortic valve surface area from a baseline stenosis-free state using heart sound components such as S1 and S2 sounds. Based on the change in aortic valve surface area, the stenosis detector can generate an aortic stenosis indicator indicating a presence and severity of aortic stenosis. Such indicator can be provided to a user, trigger symptom monitoring and evaluation of functional deterioration in the patient, facilitate assessment of patient candidacy for aortic valve replacement, or triage heart failure management strategies.
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
81.
AORTIC STENOSIS SEVERITY QUANTIFICATION USING HEART SOUNDS
Systems and methods for monitoring and managing aortic stenosis are disclosed. An exemplary medical-device system comprises a data receiver to receive heart sound information sensed by ambulatory heart sound sensors, and a stenosis detector to detect a change in aortic valve surface area from a baseline stenosis-free state using heart sound components such as S1 and S2 sounds. Based on the change in aortic valve surface area, the stenosis detector can generate an aortic stenosis indicator indicating a presence and severity of aortic stenosis. Such indicator can be provided to a user, trigger symptom monitoring and evaluation of functional deterioration in the patient, facilitate assessment of patient candidacy for aortic valve replacement, or triage heart failure management strategies.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61B 5/28 - Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électrocardiographie [ECG]
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
82.
SLEEP DETECTION USING CARDIAC AND RESPIRATION INFORMATION
Systems and methods for monitoring and staging sleep using cardiac and respiration information are disclosed. An exemplary system comprises a storage device to store a trained hybrid sleep detection and classification model that comprise a plurality of trained machine-learning models each trained to map input cardiac and respiratory data into one of multiple distinct model-specific awake or sleep classes, and a trained regression model to combine the model-specific awake or sleep classes to a composite awake or sleep classification. A sleep detector applies patient cardiac and respiratory information to the trained hybrid sleep detection and classification model to determine a composite awake or sleep classification for the patient. The composite awake or sleep classification is used to diagnose medical conditions including sleep apnea.
Embodiments herein relate to implantable medical devices. In an embodiment, an implantable medical device is included having a biocompatible housing, a control circuit that can disposed within the biocompatible housing, and a wireless communications transceiver. The wireless communications transceiver can be configured to communicate wirelessly through a first channel using a standard BLUETOOTH protocol (non-DSSS) and communicate wirelessly through a second channel using a direct sequence spread spectrum (DSSS) protocol over a BLUETOOTH frequency band. Other embodiments are also included herein.
Medical devices and methods for making and using medical devices are disclosed. An example medical device may include an implantable medical device. The implantable medical device may include an implantable pacing member having a housing and a lead input. A lead may be coupled to the lead input. The lead may be designed to extend along a pericardial space, epicardium, or both and engage a heart chamber. A passageway may be defined along a portion of the length of the lead.
Embodiments herein relate to optical chemical sensor systems that can be wearable and include microneedle arrays. In an embodiment, a chemical sensing device is included having a set of microneedles and a sensor element. The sensor element can include a first low-index gel layer, a second low-index gel layer, and a chromoionophore sensing film disposed between the first low-index gel layer and the second low-index gel layer. In an embodiment, a delay layer can be disposed between the sensor element and the set of microneedles. An optical emitter can be configured to emit light into the sensor element. An optical detector can be configured to receive light from the sensor element. Other embodiments are also included herein.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 5/1459 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale invasifs, p. ex. introduits dans le corps par un cathéter
A61B 5/1468 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques
Embodiments herein relate to optical chemical sensor systems that can be wearable and include microneedle arrays. In an embodiment, a chemical sensing device can be included having an optical transmission layer. The optical transmission layer can define a plurality of microneedles. The chemical sensing device can include a plurality of sensor elements and one or more optical emitters, wherein the one or more optical emitters can be configured to emit light into the plurality of sensor elements. The chemical sensing device can also include a plurality of optical detectors, wherein the plurality of optical detectors can be configured to receive light from the plurality of sensor elements. Other embodiments are also included herein.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/1459 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale invasifs, p. ex. introduits dans le corps par un cathéter
Embodiments herein relate to optical chemical sensor systems that can be wearable and include microneedle arrays. In an embodiment, a chemical sensing device is included having a set of microneedles and a sensor element. The sensor element can include a first low-index gel layer, a second low-index gel layer, and a chromoionophore sensing film disposed between the first low-index gel layer and the second low-index gel layer. In an embodiment, a delay layer can be disposed between the sensor element and the set of microneedles. An optical emitter can be configured to emit light into the sensor element. An optical detector can be configured to receive light from the sensor element. Other embodiments are also included herein.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/1459 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale invasifs, p. ex. introduits dans le corps par un cathéter
88.
INVALID FEATURE MANAGEMENT FOR COMPOSITE HEALTH INDEX
Systems and methods are disclosed to determine a composite health index for the patient as a function of a plurality of features, including determining validity of a first feature of the plurality of features and adjusting the function used to determine the composite health index in response to a determination that the first feature is not valid.
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
Systems and methods are disclosed to determine a composite health index for the patient as a function of a plurality of features, including determining validity of a first feature of the plurality of features and adjusting the function used to determine the composite health index in response to a determination that the first feature is not valid.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
Systems and methods for cardiac pacing are described in this document. A medical system includes an electrostimulation circuit to generate His-bundle pacing (HBP) pulses to capture a His bundle, and LV pacing (LVP) pulses to capture a left ventricle. A sensing circuit may sense a cardiac activity, such as an atrial or an LV cardiac electrical activity. The system includes a control circuit controlling the delivery of HBP and LVP pulses. The HBP and LVP may be delivered concurrently or sequentially. In an example, the LVP pulses may be delivered based on a His-bundle capture status in response to the HBP pulse. The system may adjust one or more His-bundle stimulation parameters based on the His-bundle capture status.
A61N 1/365 - Stimulateurs cardiaques commandés par un paramètre physiologique, p. ex. par le potentiel cardiaque
A61N 1/368 - Stimulateurs cardiaques commandés par un paramètre physiologique, p. ex. par le potentiel cardiaque comprenant plus d'une électrode coopérant avec différentes régions du cœur
98.
IMPLANTABLE CHEMICAL SENSOR PACKAGES WITH CALIBRATION FEATURES
Embodiments herein relate to embodiments herein relate to packages for implantable chemical sensors with features to facilitate calibration of the sensors therein. In an embodiment, a chemical sensor system is included having a package and an implantable monitor device therein. The implantable monitor device can include an optical chemical sensor. A first aqueous solution including a solute can be disposed within the package. In some embodiments, the package includes a first chamber a second chamber separated by a frangible seal. A first aqueous solution can be disposed within the first chamber and a second aqueous solution can be disposed in the second chamber. Other embodiments are also included herein.
A61B 5/1473 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques invasifs, p. ex. introduits dans le corps par un cathéter
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/1495 - Étalonnage ou test des sondes in vivo
99.
CONDUCTION SYSTEM PACING OPTIMAL OUTPUT SETTING INDICATOR
A method of operating a cardiac rhythm management (CRM) system includes sending a list of electrodes to an ambulatory medical device (AMD) of the CRM system from a programming device for the AMD, the list of electrodes including types of electrodes available to the AMD and position of the electrodes; sending a selection of one or more capture confirming criteria to confirm pacing capture to the AMD; performing, by the AMD, an automatic pacing threshold test for all potential pacing vectors that include the electrodes in the list of electrodes; collecting data for each pace of the pacing threshold test confirmed to capture according to the selected one or more capture confirming criteria; communicating the collected data to the programming device; and presenting the collected data as a trend relative to at least one selected capture confirming criterion and the pacing stimulation energy that resulted in capture.
A method of operating a cardiac rhythm management (CRM) system includes measuring a baseline PR interval of a cardiac depolarization; measuring one or both of a heart sound and a QRS width for the cardiac depolarization; delivering pacing stimulation according to an atrial sense to ventricular pace interval (AsVp interval) and measuring the one or both of the heart sound and the QRS width for the AsVp interval, wherein the pacing stimulation is delivered using a conduction system pacing (CSP) vector that includes an electrode positioned in an interventricular septum; delivering pacing stimulation according to an atrial pace to ventricular pace interval (ApVp interval) and measuring the one or both of the heart sound and the QRS width for the ApVp interval; and generating a recommended atrial to ventricular delay setting for CSP according to the measured one or both of the heart sounds and the QRS widths.
A61N 1/368 - Stimulateurs cardiaques commandés par un paramètre physiologique, p. ex. par le potentiel cardiaque comprenant plus d'une électrode coopérant avec différentes régions du cœur
A61N 1/365 - Stimulateurs cardiaques commandés par un paramètre physiologique, p. ex. par le potentiel cardiaque
