Abrégé

The connection clamp (1) has two clamp ends and a double ring structure, so that two parallel clamping elements (11, 12) are provided, of C-shape at ring parts thereof, sharing a same longitudinal axis (X). Corresponding interlocking parts (11f, 12f) are carried by the elements (11, 12), to form two pairs of jaws in a clamp end for engagement of two tongue members that belong to the other clamp end. A bridging portion (31) fixedly connects a first pair of jaws to the second pair of jaws with a predetermined spacing. The clamp allows connecting a flexible tube (T) to a barb connector (9) protruding into a tube end, with a circumferential radial bulge of the tube, formed at location of the barb (19), passing between the clamping elements, while a radial interspace is left relative to the bridging portion to prevent any clamp contact with the bulge.

Classes IPC  ?

• F16L 33/035 - Colliers de serrage pour manches fixés au moyen de dents ou de crochets

Abrégé

The connector (1) has a valve assembly with a tubular body (2), a plug (15) movable inside the body and a sleeve (20) to control plug position. A flange (3) on the body (2) delimits a recess where a latch (10) can interact with an inserting male part of a complementary connector or analogous structure. The connector comprises an aseptic attachment interface (5) at a front open end (2b) with a removable membrane (M). For aseptic fluid management in a connection involving two connectors, the connector (1) is configured to allow a disconnection after two successive steps, which are: moving the plug (15) in a closing position by a first manual actuation using the sleeve, and then displacing the latch by a second manual actuation using an external actuator (12) partly covering the flange and which is released by moving an blocker (14) in response to the first actuation.

Classes IPC  ?

• A61M 39/18 - Procédés ou appareils pour réaliser les connexions sous conditions stériles
• A61M 39/10 - Raccords ou accouplements pour tubes
• A61M 39/24 - Soupapes de retenue ou soupapes anti-retour

Abrégé

The connector (1) has a body (2) provided with a flange (3), forming a central opening (O) between a female member (31) and a male member (32). The planar flange face (F3) has an axial access (30) of the female member and the male member (32) protrudes axially from the flange face. A membrane (M) removably attached to the connector covers this face to seal the opening, so that a genderless connecting device is obtained, allowing mating engagement of the connector (1) with an identical complementary connector (101). A clipping interface forming the female member allows locking a pre-coupled state of these connectors (1, 101) with each membrane still present. The flange of the connector (1) houses a slider (10) adapted to contact the mating insert (104) of the male member engaged through the axial access (30). The slider allows locking and/or unlocking a final position of the insert.

Classes IPC  ?

• A61M 39/10 - Raccords ou accouplements pour tubes
• A61M 39/18 - Procédés ou appareils pour réaliser les connexions sous conditions stériles

Abrégé

The connector arrangement has a connector (1) provided with a plug (15) movable inside a tubular body. A blocking part (12a), clipped around the body (2), provisionally locks a retracted open position of the plug, to retain the plug away from a plug seating surface provided near a front central opening of the connector, where a junction plane extends for a coupled state of the connector (1) with a compatible/identical connector (101). An aseptic attachment structure (5) with membrane (M) initially seals the opening. A fluid connection system (100) with a pair of interlocked connector arrangements allows synchronizing membrane removal with unlocking of the respective plugs (15), by forming a removably clippable assembly including the blocking parts (12a, 12b). Each membrane of attachment structure is secured to the clip assembly (12) to be pulled, radially outward, with this assembly. Return means (20) may push the plugs for having aseptic disconnection.

Classes IPC  ?

• A61M 39/10 - Raccords ou accouplements pour tubes
• A61M 39/16 - Raccords ou accouplements pour tubes avec des dispositions pour la désinfection ou la stérilisation

Abrégé

The invention relates to a method for connecting a first connection region (6a) to a second connection region (6b). The connection regions (6a, 6b) consist of silicone. In order to establish a connection between the connection regions (6a, 6b), VUV beams (7) are applied to the regions. At the same time or subsequently, the connection regions (6a, 6b) are pressed against one another. The method according to the invention can be used as follows: for connecting the end faces of two silicone tubes; for connecting an inner surface of a silicone tube to a lateral surface of a connecting piece made of silicone; or for producing a sealed-off closure point of a silicone tube, which can then be severed in order to provide two sealed-off closed silicone tube parts.

Classes IPC  ?

• B29C 65/14 - Assemblage d'éléments préformésAppareils à cet effet par chauffage, avec ou sans pressage par énergie ondulatoire ou rayonnement corpusculaire
• B29C 65/48 - Assemblage d'éléments préformésAppareils à cet effet en utilisant des adhésifs
• B29C 65/74 - Assemblage d'éléments préformésAppareils à cet effet par soudage et découpage
• B29K 83/00 - Utilisation de polymères contenant dans la chaîne principale uniquement du silicium avec ou sans soufre, azote, oxygène ou carbone comme matière de moulage

Abrégé

The clamping device (1) has a body having opposite openings (31, 32) forming a passageway for flexible hose. Two jaws allow a hose clamping, in a closed position maintained at jaw front ends by a tongue (5) engaged with complementary securing means (TS). An upper jaw (11) is downwardly movable to close the device when pushing a top pressing surface (PS). The body has a left body part and a right body part, interconnected at a connector section (CC). The front end (E1) of first jaw comprises the tongue (5) and a hollow upper bulge (B1) offset upwardly. This front end consists of two halves, one of which is arranged at front end of a first connector section belonging to a body part. The first connector section has an insert (41) extending inside said bulge and engaged in a transverse passage of the second half forming the second connector section.

Classes IPC  ?

• A61M 39/28 - Moyens de serrage pour l'écrasement des tubes flexibles, p. ex. brides de serrage à rouleaux
• A61M 39/08 - TubesMoyens de rangement spécialement adaptés aux tubes

Abrégé

A hose clamp (1) with two passages (31, 32) distributed in two clamping jaws (11, 12) includes two clamping parts (8a, 8b), between which a hose segment of a flexible hose passing through the two passages can be nipped in closed state of the clamp (1). Offset the hose passageway, two clamp ends (E1, E2) have interacting securing elements that anchor the clamping jaws (11, 12) in a closing position, one of these ends (E2) having a securing surface (TS) with at least one retaining rib or tooth facing inwardly, while the other end (E1) is actuatable in response to a pushing action and provided with a tongue (5). Two outer lips (9) are provided at the two respective ends. In expanded state of the clamp, the tongue (5) is transverse to the securing surface (TS) and protrudes outwardly, entirely inside a mouth region (ZD) delimited between the outer lips.

Classes IPC  ?

• A61M 39/28 - Moyens de serrage pour l'écrasement des tubes flexibles, p. ex. brides de serrage à rouleaux
• F16K 7/06 - Dispositifs d'obturation à diaphragme, p. ex. dont un élément est déformé, sans être déplacé entièrement, pour fermer l'ouverture à diaphragme tubulaire dont l'étranglement est assuré par une force extérieure radiale par tige filetée, came ou autre moyen mécanique

Abrégé

A radiation dose sensor that measures a radiation dose of a biocontainer formed for a first material includes a first electrode, a second electrode, and a film. The first electrode has a plurality of first fingers. And the second electrode has a plurality of second fingers. The fingers of the first electrode extend towards and are interdigitated with the fingers of the second electrode that extend towards the first electrode with gaps formed between the first and second fingers. The film coats the interdigitated fingers and is disposed within the gaps. The film is formed of a second material that is similar to the first material that forms the biocontainer.

Classes IPC  ?

• G01T 1/167 - Mesure du contenu radioactif des objets, p. ex. contamination
• G01T 1/02 - Dosimètres
• G01T 1/24 - Mesure de l'intensité de radiation avec des détecteurs à semi-conducteurs

Abrégé

A method of measuring a radiation dosage during irradiation includes disposing a first sensor in a first package with a first biocontainer and disposing a second sensor in a second package with a second biocontainer. The method further includes placing the first package and the second package in a container and irradiation the container including the first package and the second package. During or after irradiation, a first radiation dosage associated with the first biocontainer is measured with the first sensor and a second radiation dosage associated with the second biocontainer is measured with the second sensor.

Classes IPC  ?

• G01T 1/02 - Dosimètres
• A61L 2/08 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des phénomènes physiques des radiations
• A61L 2/26 - Accessoires

Abrégé

A union for connecting a first fluid conduit and a second fluid conduit includes a body. The body defines a central passage about a central longitudinal axis of the body with the body having a first side and a second side. The body is configured to define a first adhesive channel between a first fluid conduit and the first side of the body and to define a second adhesive channel between a second fluid conduit and the second side of the body. The body defining an injection port position at a midpoint of the body. The injection port in fluid communication with the first adhesive channel and the second adhesive channel and is configured to deliver adhesive into the first adhesive channel and the second adhesive channel.

Classes IPC  ?

• F16L 25/00 - Structure ou détails de raccords de tuyaux non prévus dans les groupes ou présentant in intérêt autre que celui visé par ces groupes
• F16L 31/00 - Dispositions d'assemblage des manches entre elles ou avec des manchons flexibles

Produits et services

Laboratory, biological pilot plant and biological production equipment specially adapted for use in pharmaceutical and biological product laboratories and testing facilities, namely, plastic bags adapted for use in holding biological material and related reagents; laboratory equipment, namely, liners of plastic for tanks used in holding biological material and related reagents; liquid handling apparatus of plastic, namely, pre-assembled tubes, pipes, bags, containers and filters for pharmaceutical or biotechnology applications; disposable plastic bioreactors for cell culture; disposable plastic bioreactors for cultivating microorganisms; bioreactors and fermenters, in particular having plastic bags, filters of plastic and sterile connector apparatus of plastic, being single-use apparatus for the pharmaceutical and biotechnological industries. Flexible plastic bags specially designed for biological, medical or pharmaceutical liquids; medical plastic bags designed to hold medical and pharmaceutical liquids; bags adapted for medical purposes, namely for cell cultivation; flexible pouches of plastic specially designed for storing and transporting biopharmaceutical liquids; flexible pouches of plastic specially designed for storing and transporting biopharmaceutical liquids having tubings and filters connected thereto. Packaging materials of plastic. Containers, not of metal, and closures and holders therefore, not of metal; containers, not of metal, for storage or transport; containers for biopharmaceutical liquids, non-metallic; packaging containers of plastic.

Produits et services

(1) Laboratory, biological pilot plant and biological production equipment specially adapted for use in pharmaceutical and biological product laboratories and testing facilities, namely, plastic bags adapted for use in holding biological material and related reagents; laboratory equipment, namely, liners of plastic for tanks used in holding biological material and related reagents; liquid handling apparatus of plastic, namely, pre-assembled tubes, pipes, bags, containers and filters for pharmaceutical or biotechnology applications; disposable plastic bioreactors for cell culture; disposable plastic bioreactors for cultivating microorganisms; bioreactors and fermenters, in particular having plastic bags, filters of plastic and sterile connector apparatus of plastic, being single-use apparatus for the pharmaceutical and biotechnological industries. (2) Flexible plastic bags specially designed for biological, medical or pharmaceutical liquids; medical plastic bags designed to hold medical and pharmaceutical liquids; bags adapted for medical purposes, namely for cell cultivation; flexible pouches of plastic specially designed for storing and transporting biopharmaceutical liquids; flexible pouches of plastic specially designed for storing and transporting biopharmaceutical liquids having tubings and filters connected thereto. (3) Packaging materials of plastic. (4) Containers, not of metal, and closures and holders therefore, not of metal; containers, not of metal, for storage or transport; containers for biopharmaceutical liquids, non-metallic; packaging containers of plastic; all the aforementioned goods not for use in relation to fuels, waste or drinking water.

Produits et services

Laboratory, biological pilot plant and biological production equipment for use in pharmaceutical and biological product laboratories and testing facilities, namely, plastic bags for use in holding biological material and related reagents; laboratory equipment, namely, liners of plastic for tanks used in holding biological material and related reagents; Liquid handling apparatus of plastic, namely, pre-assembled tubes, pipes, bags, containers and filters for pharmaceutical or biotechnology applications; Disposable plastic bioreactors for cell culture; Disposable plastic bioreactors for cultivating microorganisms; Bioreactors and fermenters, in particular having plastic bags, filters of plastic and sterile connector apparatus of plastic, being single-use apparatus for the pharmaceutical and biotechnological industries. Flexible plastic bags for biological, medical or pharmaceutical liquids; Medical plastic bags designed to hold medical and pharmaceutical liquids; Bags for medical purposes, namely for cell cultivation; Flexible pouches of plastic for storing and transporting biopharmaceutical liquids; Flexible pouches of plastic for storing and transporting biopharmaceutical liquids having tubings and filters connected thereto. Packaging materials of plastic. Containers, and closures and holders therefore, non-metallic; Containers, not of metal, for storage or transport; Containers for biopharmaceutical liquids, non-metallic; Packaging containers of plastic; all the aforementioned goods not for use in relation to fuels, waste or drinking water.

Abrégé

A sterile filling unit, of a basic container with contents that can be distributed in a fluid form and that is originally located in a source container in a sterile manner, includes a sterile chamber with at least one sterile entry port and/or outlet; a sterile fluid transfer and filling line with an intake and an outlet, such that for a filling stage the line passes through the wall of the sterile chamber in a sterile manner, with the intake located outside of the sterile chamber in sterile fluid communication with the source container, with the filling element at the outlet located inside the sterile chamber and positioned to be operating; and a unit that can introduce the disposable internal elements that, in a stage prior to the filling stage, were located outside of the sterile chamber, into the interior of the sterile chamber in a sterile manner.

Classes IPC  ?

• B65B 31/02 - Remplissage, fermeture, ou remplissage et fermeture, de réceptacles dans des chambres maintenues en dépression ou en surpression ou contenant une atmosphère spéciale, p. ex. du gaz inerte
• B65B 3/00 - Emballage de matériaux plastiques, de semi-liquides, de liquides ou de liquides et solides mélangés, dans des réceptacles ou récipients individuels, p. ex. dans des sacs ou sachets, boîtes, cartons, bidons ou pots

Produits et services

Liquid filter units, namely, filter cartridges, plastic hoses and hose connectors, sold as a set, for filtering machines; liquid filter units, namely, pre-assembled filter cartridges, plastic hoses and hose connectors, sold as a set, for filtering machines; disposable connector elements to provide fluid connection between tubes, pipes, bags, containers and filters, for use in fluid processing apparatus of plastic; liquid processing apparatus of plastic consisting of tubes, pipes, bags, containers and filters being in fluid communication with each other. Laboratory filters; filtering units for laboratory use; liquid filter units, namely, filter cartridges, plastic hoses and hose connectors, sold as a set, for laboratory use; liquid filter units, namely, pre-assembled filter cartridges, plastic hoses and hose connectors, sold as a set, for laboratory use; sensor units, namely, pressure sensors and flow sensors, plastic hoses and hose connectors, sold as a set; pre-assembled sensor units, namely, pre-assembled pressure sensors, flow sensors, plastic hoses and hose connectors, sold as a set; apparatus for sterile connection of plastic vessels, including plastic tubes, pipes, bags, containers; apparatus of plastic with communicating connections, including tubes, pipes, bags, containers and filters for pharmaceutical or biotechnology applications. Filters and filtering units for medical use; liquid filter units, namely, filter cartridges, plastic tubes and tube connectors, sold as a set, for medical use; pre-assembled liquid filter units, namely, pre-assembled filter cartridges, plastic tubes and tube connectors, sold as a set, for medical use; containers with tubes for holding biopharmaceutical fluids for medical use; filtration devices with tubes for processing biopharmaceutical fluids for medical use. Liquid filters and filtering units, for industrial use; filters for filtering fluids, filter modules, filter candles and filter capsules; liquid filter units, namely, filter cartridges, plastic hoses and hose connectors, sold as a set, for industrial use; pre-assembled liquid filter units, namely, pre-assembled filter cartridges, plastic hoses and hose connectors, sold as a set, for industrial use. Flexible pipes, tubes and hoses, not of metal; non-metallic hose connectors; non-metallic hose couplings; nonmetallic disposable connector elements to provide fluid connection between tubes, pipes, bags, containers and filters, all made of plastic.

Produits et services

(1) Liquid filter units, namely, filter cartridges, plastic hoses and hose connectors, sold as a set, for filtering machines; liquid filter units, namely, pre-assembled filter cartridges, plastic hoses and hose connectors, sold as a set, for filtering machines; disposable connector elements to provide fluid connection between tubes, pipes, bags, containers and filters, for use in fluid processing apparatus of plastic; liquid processing apparatus of plastic consisting of tubes, pipes, bags, containers and filters being in fluid communication with each other. (2) Laboratory filters; filtering units for laboratory use; liquid filter units, namely, filter cartridges, plastic hoses and hose connectors, sold as a set, for laboratory use; liquid filter units, namely, pre-assembled filter cartridges, plastic hoses and hose connectors, sold as a set, for laboratory use; sensor units, namely, pressure sensors and flow sensors, plastic hoses and hose connectors, sold as a set; pre-assembled sensor units, namely, pre-assembled pressure sensors, flow sensors, plastic hoses and hose connectors, sold as a set; apparatus for sterile connection of plastic vessels, including plastic tubes, pipes, bags, containers; apparatus of plastic with communicating connections, including tubes, pipes, bags, containers and filters for pharmaceutical or biotechnology applications. (3) Filters and filtering units for medical use; liquid filter units, namely, filter cartridges, plastic tubes and tube connectors, sold as a set, for medical use; pre-assembled liquid filter units, namely, pre-assembled filter cartridges, plastic tubes and tube connectors, sold as a set, for medical use; containers with tubes for holding biopharmaceutical fluids for medical use; filtration devices with tubes for processing biopharmaceutical fluids for medical use. (4) Liquid filters and filtering units, for industrial use; filters for filtering fluids, filter modules, filter candles and filter capsules; liquid filter units, namely, filter cartridges, plastic hoses and hose connectors, sold as a set, for industrial use; pre-assembled liquid filter units, namely, pre-assembled filter cartridges, plastic hoses and hose connectors, sold as a set, for industrial use. (5) Flexible pipes, tubes and hoses, not of metal; non-metallic hose connectors; non-metallic hose couplings; nonmetallic disposable connector elements to provide fluid connection between tubes, pipes, bags, containers and filters, all made of plastic.

Produits et services

liquid filter sets for filtering machines used for process filtration in the biopharmaceutical industry comprising cartridges in the nature of fluid filters, plastic hoses, and plastic hose connectors, sold as a set; liquid filter sets for filtering machines used for process filtration in the biopharmaceutical industry comprising pre-assembled cartridges in the nature of fluid filters, plastic hoses, and plastic hose connectors, sold as a set; parts for machines that process industrial fluids, namely, disposable plastic connectors for tubes, pipes, bags, containers, and filters; bioprocess apparatus in the nature of plastic machines for use in handling and processing of bioprocess fluids, consisting of connected tubes, pipes, bags, containers, and fluid filter cartridges laboratory filters; filtering units for laboratory use comprising cartridges in the nature of fluid filters, plastic hoses, and plastic hose connectors; liquid filter units, namely, laboratory filter sets for liquids comprising filter cartridges, plastic hoses, and hose connectors sold as a unit; liquid filter units, namely, laboratory filter sets for liquids comprising pre-assembled filter cartridges, plastic hoses, and hose connectors sold as a unit; sensor sets comprising pressure sensors, liquid flow sensors, plastic hoses, and hose connectors, sold as a set; pre-assembled sensor sets comprising pre-assembled pressure sensors, liquid flow sensors, plastic hoses, and hose connectors, sold as a set; laboratory equipment, namely, sterile connectors for plastic vessels being plastic tubes, pipes, bags, containers; laboratory apparatus for use in handling and processing of biopharmaceutical fluids, made of plastic, comprising connected tubes, pipes, bags, containers, and fluid filter cartridges, for pharmaceutical or biotechnology applications filters and filtering units for medical use, namely, fluid filters for biological and cellular products; liquid filter sets for medical purposes comprising filter cartridges in the nature of cellular and biological product filters and biopharmaceutical fluid filters, plastic tubes, and tube connectors, sold as a set; pre-assembled liquid filter sets for medical purposes comprising pre-assembled filter cartridges in the nature of cellular and biological product filters and biopharmaceutical fluid filters, plastic tubes, and tube connectors, sold as a set; Containers for biological and cellular products that incorporate tubes for medical use; medical filtration devices in the nature of fluid filters for biological and cellular products that incorporate tubes bioprocess liquid filters in the nature of membrane filter cartridges for the purification of biopharmaceutical liquids for use in handling and processing of bioprocess fluids in biopharmaceutical production, for industrial use; bioprocess liquid filtering units in the nature of membrane filter cartridges for the purification of biopharmaceutical liquids for use in handling and processing of bioprocess fluids in biopharmaceutical production, namely, connected tubes, pipes, bags, containers, and fluid filter cartridges, for industrial use; bioprocess filter modules in the nature of membrane filter cartridges for the purification of biopharmaceutical liquids for use in handling and processing of bioprocess fluids in biopharmaceutical production in the nature of replacement filter cartridges and filters for bioprocess filtration units; industrial liquid filter sets consisting of membrane filter cartridges for the purification of biopharmaceutical liquids for use in handling and processing of bioprocess fluids in biopharmaceutical production, comprising filter cartridges, plastic hoses, and hose connectors sold as a unit; pre-assembled industrial liquid filter sets for use in handling and processing of bioprocess fluids, comprising pre-assembled filter cartridges, plastic hoses, and hose connectors sold as a unit for the purification of biopharmaceutical liquids in biopharmaceutical production flexible non-metal pipes, tubes and hoses; non-metallic couplings for use with flexible non-metal hoses; non-metallic hose couplings; non-metallic disposable plastics couplings to provide fluid connection between plastic tubes, pipes, bags, containers, and filters

Abrégé

The stirring device, in particular for a fluid-mixing bioreactor, comprises a drive shaft including a rod, an agitating element and a sleeve of tubular shape. The sleeve forms a coupling sleeve receiving the shaft therethrough and is directly rotationally coupled to the rod. The agitating element, which has a hub with an annular side wall delimiting an inner space and an impeller assembly comprising blades, is indirectly rotationally coupled to the rod via the sleeve that is engaged in the inner space. One of an inner surface of the wall and an outer surface of the sleeve is a guiding surface with progressively reduced cross section. Axial movement between the hub and the sleeve is prevented in a locked configuration of a sleeve fastening arrangement. Hub-sleeve contact areas can be axially distributed.

Classes IPC  ?

• C12M 1/06 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'introduction de gaz avec agitateur, p. ex. avec agitateur à turbine
• B01F 27/07 - Agitateurs caractérisés par leur montage sur l’arbre
• B01F 27/1111 - Agitateurs centrifuges, c.-à-d. agitateurs à sortie radialeAgitateurs de type turbine, p. ex. avec des moyens pour guider le flux avec un disque plat ou avec un élément en forme de disque équipé de pales, p. ex. une turbine de Rushton
• B01F 27/113 - Agitateurs en forme d'hélice pour produire un écoulement axial, p. ex. en forme d'hélice de navire ou d'avion
• B01F 27/191 - Agitateurs avec plusieurs éléments de mélange montés en séquence sur un même axe avec des éléments similaires
• B01F 27/192 - Agitateurs avec plusieurs éléments de mélange montés en séquence sur un même axe avec des éléments dissemblables
• B01F 35/41 - Montage ou support des arbres d'agitation ou des unités d'agitation sur les récipients
• B01F 35/513 - Récipients souples, p. ex. sacs supportés par des conteneurs rigides
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• B01F 101/22 - Mélange d'ingrédients pour compositions pharmaceutiques ou médicales

Abrégé

Integrity of a flexible bag is verified by a testing system, using helium to detect existence of a possible hole. The bag is preliminary placed in vacuum chamber of a fluid-tightly isolated enclosure. After connecting a port of the bag to a helium feeding pipe and after pre-pressurizing the bag with nitrogen, a test is performed in a vacuum suction mode for a detection area outside the bag in the enclosure. Before starting the test phase, the bag is additionally filled with an amount of helium. A detection detects information representative of helium partial pressure in the internal volume, to allow detection of helium escaping from the bag, by analysis of a helium partial pressure drop. A small amount of nitrogen is sufficient to decrease leak rate mean value, so that uncertainty regarding integrity of some bags decreases.

Classes IPC  ?

• G01M 3/22 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs pour tuyaux, câbles ou tubesExamen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs pour raccords ou étanchéité de tuyauxExamen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs pour soupapes
• G01M 3/32 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par mesure du taux de perte ou de gain d'un fluide, p. ex. avec des dispositifs réagissant à la pression, avec des indicateurs de débit pour récipients, p. ex. radiateurs

Abrégé

Integrity of a flexible bag already filled with a biopharmaceutical fluid is verified by a receiving and controlling device. The first wall and a second wall, forming two opposite walls on both sides of a longitudinal axis of the bag, are in contact with the fluid and with two parallel restraining plates of the device, while test pressure is controlled. Additionally, an integrity/non-integrity indicator device that comprises a pair of covering walls is provided to be interposed between the bag walls and the restraining plates. A leak through the bag walls can be detected by a color change of at least one continuous colorimetric detection layer, integral with or included in the pair of covering walls. Such continuous colorimetric detection layer is included in a permeable or impregnable layer.

Classes IPC  ?

• G01M 3/04 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite
• G01M 3/38 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation de la lumière

Produits et services

Liquid filter units, namely, filter cartridges, plastic hoses and hose connectors, sold as a set, for filtering machines; liquid filter units, namely, pre-assembled filter cartridges, plastic hoses and hose connectors, sold as a set, for filtering machines; disposable elements for creating and separating communicating connections between apparatus of plastic, including tubes, pipes, bags, containers and filters; communicating apparatus of plastic, including tubes, pipes, bags, containers and filters. Laboratory filters; filtering units for laboratory use; liquid filter units, namely, filter cartridges, plastic hoses and hose connectors, sold as a set, for laboratory use; liquid filter units, namely, pre-assembled filter cartridges, plastic hoses and hose connectors, sold as a set, for laboratory use; sensor units, namely, pressure sensors and flow sensors, plastic hoses and hose connectors, sold as a set; pre-assembled sensor units, namely, pre-assembled pressure sensors, flow sensors, plastic hoses and hose connectors, sold as a set; apparatus for sterile connection of plastic vessels, including plastic tubes, pipes, bags, containers; Apparatus of plastic with communicating connections, including tubes, pipes, bags, containers and filters for pharmaceutical or biotechnology applications. Filters and filtering units for medical use; liquid filter units, namely, filter cartridges, plastic tubes and tube connectors, sold as a set, for medical use; pre-assembled liquid filter units, namely, pre-assembled filter cartridges, plastic tubes and tube connectors, sold as a set, for medical use; containers with tubes for holding biopharmaceutical fluids; filtration devices with tubes for processing biopharmaceutical fluids. Filters and filtering units, for industrial use; filters for filtering fluids, filter modules, filter candles and filter capsules; liquid filter units, namely, filter cartridges, plastic hoses and hose connectors, sold as a set; pre-assembled liquid filter units, namely, pre-assembled filter cartdriges, plastic hoses and hose connectors, sold as a set. Flexible pipes, tubes and hoses, not of metal; non-metallic hose connectors, non-metallic hose clamps; non-metallic hose couplings; disposable elements for creating and separating communicating connections between apparatus of plastic, namely flexible pipes, tubes, hoses and filters.

Abrégé

A stopper configured to hermetically close a nozzle intended to contain a biopharmaceutical fluid with a cylindrical bore of diameter (D1) and a flange having a groove. The stopper has a body with a front part with a cylindrical outer wall about an axis A, with a diameter at rest greater than (D1), intended to be received under stress in the cylindrical bore of the nozzle, a stop disc extending a rear part of the body radially towards the outside and extending in a plane transverse to the axis. The body and the stop disc are rotationally symmetric about the axis A. The stop disc includes an annular bulge, interposed radially between a first annular shoulder and a second annular shoulder, the bulge extending forward from the stop disc and being intended to be received in the groove in the flange of the nozzle.

Classes IPC  ?

• B65D 39/00 - Fermetures disposées dans les cols, les orifices verseurs ou les ouvertures de décharge, p. ex. bouchons
• B65D 39/16 - Fermetures disposées dans les cols, les orifices verseurs ou les ouvertures de décharge, p. ex. bouchons avec poignées ou autres moyens particuliers facilitant la manutention
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• B65D 47/12 - Fermetures avec dispositifs de décharge autres que des pompes avec goulottes ou tubes de déversementFermetures avec dispositifs de décharge autres que des pompes avec tuyères ou passages pour la décharge ayant des fermetures amovibles

Abrégé

Integrity of a flexible bag is verified by a testing system, using helium to detect existence of a possible hole. The flexible bag is preliminary placed in vacuum chamber of a fluid-tightly isolated enclosure. After connecting a port of the bag to a helium feeding pipe, vacuum suction is performed to obtain vacuum outside the bag in the enclosure. Then, a first amount of helium is diffused in the internal volume of the enclosure through a gas permeable wall, to increase helium partial pressure outside the flexible bag. After, in a test phase while said vacuum suction is still performed, the bag is filled with a second amount of helium. A detector detects information representative of helium partial pressure in the internal volume, to allow detection of helium escaping from the bag, by analysis of a helium partial pressure drop.

Classes IPC  ?

• G01M 3/20 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs
• G01M 3/32 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par mesure du taux de perte ou de gain d'un fluide, p. ex. avec des dispositifs réagissant à la pression, avec des indicateurs de débit pour récipients, p. ex. radiateurs

Abrégé

A biopharmaceutical liquid reservoir, includes a bag forming an inner storage space for storing a biopharmaceutical liquid, a mechanical member located at a wall of the bag, having: a stationary set of parts that is stationary with respect to the wall of the bag, a rotating set of parts rotating about an axis of rotation with respect to the stationary set, a bearing located between the two sets and, inside the bag, a communication passage: separating the bearing from the inner storage space, including one or more changes of direction, being formed by a portion of the parts of the rotating set located opposite a portion of the parts of the stationary set.

Classes IPC  ?

• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• A61J 1/10 - Récipients du type sac
• C12M 1/04 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'introduction de gaz
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse

Abrégé

A device for emptying a flexible bag comprising a fluid product, comprising a tray including a base having at least a top flat surface and two side members rigidly mounted on the base, perpendicularly to the base, the base being arranged substantially horizontally, namely along a front-rear direction and a left-right direction, a pressure element having at least a flat bottom face, for pressing downwards on a flexible bag under the influence of gravity. The tray includes guiding means for guiding the pressure element, as it goes downwards when the bag is emptying. The pressure element exhibits a gravity center and a geometric center, the gravity center being away from the geometric center.

Classes IPC  ?

• B65D 35/28 - Réceptacles pliables, de forme tubulaire, conçus de telle sorte que l'expulsion de leur contenu leur donne une déformation permanente, p. ex. tubes souples pour dentifrice ou autres produits plastiques ou semi-liquidesSupports adéquats avec dispositifs accessoires pour expulser les contenus
• B65B 69/00 - Déballage des objets ou matériaux non prévu ailleurs
• G01M 3/00 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide

Abrégé

A method for producing a single-use container, particularly a single-use bioreactor, an assembly system, and a single-use container particularly a single-use bag such as a single-use bioreactor comprising: a base material; and at least one functional element being at least partially connected with the base material, wherein the functional element is obtained by a three dimensional printing technique from at least one printable material, wherein the printable material is heated during the three dimensional printing thereby at least partly connecting the printed functional element to the base material.

Classes IPC  ?

• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• B33Y 80/00 - Produits obtenus par fabrication additive
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 40/20 - Posttraitement, p. ex. durcissement, revêtement ou polissage
• B29C 64/357 - Recyclage
• B29C 64/35 - Nettoyage
• B33Y 30/00 - Appareils pour la fabrication additiveLeurs parties constitutives ou accessoires à cet effet
• B29C 64/245 - Plates-formes ou substrats
• B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p. ex. modélisation par dépôt de fil en fusion [FDM]

Abrégé

A 3-D flexible bag to be filled with a biopharmaceutical product is formed by assembling of two wall elements and two gussets. At least one connection port is provided, for filling and/or emptying. A substantially parallelepipedal configuration is obtained in a filled state thanks to the unfolding of the gussets combined with the folding of flaps of the two wall elements. A transverse weld, formed at one end, connects the two wall elements of the bag and extends continuously, keeping in a folded-flat state:—an elongate edge portion of one gusset;—an elongate edge portion of the other gusset. This transverse weld has a length corresponding to a determined dimension of the flexible bag in the parallelepipedal configuration.

Classes IPC  ?

• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
• A61J 1/10 - Récipients du type sac
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• B65D 30/20 - Sacs, sachets ou réceptacles analogues caractérisés par leur forme ou leur conception comportant des plis, p. ex. pour faciliter le repliage

Abrégé

A sterile filling unit, of a basic container with contents that can be distributed in a fluid form and that is originally located in a source container in a sterile manner, includes a sterile chamber with at least one sterile entry port and/or outlet; a sterile fluid transfer and filling line with an intake and an outlet, such that for a filling stage the line passes through the wall of the sterile chamber in a sterile manner, with the intake located outside of the sterile chamber in sterile fluid communication with the source container, with the filling element at the outlet located inside the sterile chamber and positioned to be operating; and a unit that can introduce the disposable internal elements that, in a stage prior to the filling stage, were located outside of the sterile chamber, into the interior of the sterile chamber in a sterile manner.

Classes IPC  ?

• B65B 3/00 - Emballage de matériaux plastiques, de semi-liquides, de liquides ou de liquides et solides mélangés, dans des réceptacles ou récipients individuels, p. ex. dans des sacs ou sachets, boîtes, cartons, bidons ou pots
• B65B 31/02 - Remplissage, fermeture, ou remplissage et fermeture, de réceptacles dans des chambres maintenues en dépression ou en surpression ou contenant une atmosphère spéciale, p. ex. du gaz inerte

Abrégé

A tight connection device for the aseptic transfer of a biopharmaceutical product includes: a stationary temporary clamping means keeping the container hermetically clamped against the chamber; a stationary unlocking means capable of switching the container from an initial locked position to an intermediate unlocked position; a stationary locking means; and an annular functional crown capable of being rotated to actuate the stationary unlocking means and the stationary locking means of the container. The stationary unlocking means and the stationary locking means are mechanically linked to the annular functional crown and arranged such that the rotation of the annular functional crown and the end locked position. The device further includes stationary immobilising/release means capable of allowing and preventing the annular functional crown to rotate.

Classes IPC  ?

• B01L 1/02 - Chambres pressuriséesLeurs sas
• A61J 1/20 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue

Abrégé

A protective container for a biopharmaceutical liquid bag comprises: a lower shell comprising a bottom and side walls; and an upper shell, said upper shell comprising a recess capable of covering the bag and being insertable in the lower shell, so that the upper shell is retained in the upper part of the side walls of the lower shell by resting on support elements located in the lower shell.

Classes IPC  ?

• A61J 1/16 - Supports pour récipients
• A61J 1/10 - Récipients du type sac
• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides

Abrégé

A bag for containing a biopharmaceutical product includes at least one fluid input/output port and a measurement opening remote from the fluid port. A probe holder port has a body with an axial through-bore and a peripheral collar with a second fastening zone and defining a fastening plane. A contact probe, extending in the axial through-bore, is assembled on the probe holder port, has an active measurement end portion in contact with the product, and has an end portion opposite the end portion. The probe holder port includes a transition portion between the body and the collar, which extends between a radially central end portion of the collar and a first axial end portion of the body. The first axial end portion is the axial end portion closest to the radially central end portion of the collar. The first axial end portion is disposed on the outer side relative to the fastening plane, and the active measurement end portion is axially disposed on the outer side relative to the fastening plane.

Classes IPC  ?

• A61J 1/10 - Récipients du type sac
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• A61J 1/18 - Dispositions pour indiquer l'état, p. ex. l'état stérile, du contenu du récipient
• A61J 1/20 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue

Abrégé

The invention relates to a protective housing for a biopharmaceutical liquid bag having a lower shell with a bottom and side walls, and an upper shell. The upper shell includes a housing for receiving the bag, and can be inserted into the lower shell, in such a way that the opening of the housing is adjacent to and facing the bottom of the lower shell, and in such a way that the upper shell is laterally held in place between the side walls of the lower shell.

Classes IPC  ?

• A61J 1/16 - Supports pour récipients
• A61J 1/10 - Récipients du type sac
• B65D 43/02 - Couvercles ou chapeaux amovibles
• B65D 21/02 - Réceptacles de forme spéciale ou pourvus de garnitures ou de pièces de fixation, pour faciliter l'emboîtement, le gerbage ou l'assemblage
• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides

Produits et services

Growing media; growing media for use in the biotechnological and biopharmaceutical sector; reagents for scientific, industrial and research purposes; growing media for scientific, laboratory and industrial use; buffers [chemicals]; buffers for use in the biotechnological and biopharmaceutical sector. Culture media for medical (human) and veterinary use; culture media for mammalian, insect and bacteriological cultures; growing media for medical or veterinary use; reagents for medical use buffers for medical or veterinary use. Scientific research services, scientific laboratory services, scientific research and development, research and development in the field of pharmaceuticals and biotechnology.

Abrégé

A method for assembling a mixer-container intended for receiving a biopharmaceutical fluid includes providing a container with a mixing device including at least one shaft having an adjustable length, and at least one first bearing attached to a wall of the container, the shaft extending at least into the inner space from the first bearing; a rigid outer device that compresses the container; and a drive motor located outside the container, the first bearing of the container is placed so as to be spaced apart from the motor, and the length of the shaft is adjusted along the main axis by arranging the shaft opposite the motor to enable the motor to rotate the shaft.

Classes IPC  ?

• B01F 13/08 - Mélangeurs magnétiques
• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
• B01F 7/16 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins avec agitateurs tournant autour d'un axe vertical
• B01F 7/22 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins avec agitateurs tournant autour d'un axe vertical à hélices
• B01F 15/00 - Accessoires pour mélangeurs
• B01F 3/04 - Mélange, p.ex. dispersion, émulsion, selon les phases à mélanger de gaz ou de vapeurs avec des liquides
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• B01F 7/00 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins

Produits et services

Cell growth media for growing cells for scientific and research use; growing media for use in the biotechnological and biopharmaceutical sector; reagents for scientific, industrial and research purposes, other than for medical or veterinary purposes; cell growing media for growing cells for laboratory and industrial use, other than for medical or veterinary purposes; chemicals, namely, buffers for scientific, industrial and research purposes; chemical buffers for use in the biotechnological and biopharmaceutical sector Culture media for cultivating human, animal, plant or microorganism cells for human medical and veterinary use; culture media for cultivating human or animal tissue for human medical and veterinary use; cell culture media for mammalian, insect and bacteriological cultures; cell growing media for medical or veterinary use; reagents for medical use; buffers for medical or veterinary use Scientific research services; scientific laboratory services; scientific research and development; scientific research and development; the aforementioned in the field of pharmaceuticals and biotechnology

Produits et services

(1) Growing media for mammalian, insect and bacteriological cell cultures; cell growth media for growing cells for use in the biotechnological and biopharmaceutical industries; cell culture reagents for scientific, and research purposes and for industrial purposes in the biotechnological and biopharmaceutical industries; cell growth media for growing cells for scientific, laboratory and industrial use in the biotechnological and biopharmaceutical industries; chemical buffers solutions; buffers solutions for use in analytical chemistry in the biotechnological and biopharmaceutical industries (2) Culture media for medical and veterinary use; culture media for mammalian, insect and bacteriological cultures; cell growth media for growing cells for medical and veterinary use; chemical reagents for use as chemical buffers solutions for medical and veterinary use (1) Scientific research services, scientific laboratory services, scientific research and development, research and development in the field of pharmaceuticals and biotechnology.

Abrégé

A pouch for transporting and/or processing a biopharmaceutical fluid, the pouch comprising a flexible wall, the flexible wall comprising a shape memory material being adapted to change shape when induced by an external stimulus, so that the pouch can be alternately in a collapsed state and in an unfolded state, the wall of the pouch in the unfolded state delimiting a closed internal cavity adapted to contain the biopharmaceutical fluid.

Classes IPC  ?

• A61J 1/10 - Récipients du type sac
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
• A61M 1/16 - Systèmes de dialyseReins artificielsOxygénateurs du sang avec membranes
• A61J 1/06 - Ampoules ou cartouches
• A61J 1/05 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour recueillir, stocker ou administrer du sang, du plasma ou des liquides à usage médical
• A61J 1/20 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue

Abrégé

A container for transporting and/or processing a biopharmaceutical fluid, the container comprising a wall, the wall comprising a shape memory material being adapted to change shape when induced by an external stimulus, so that the container can be alternately in a collapsed state and in an unfolded state, the wall of the container in the unfolded state delimiting an internal cavity adapted to contain the biopharmaceutical fluid.

Classes IPC  ?

• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• A61J 1/10 - Récipients du type sac
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
• B65D 6/16 - Réceptacles dont le corps est formé par jonction ou liaison de plusieurs composants rigides ou sensiblement rigides, constitués en totalité ou principalement en métal, en matière plastique, en bois ou en un matériau de remplacement pliables
• B65D 21/08 - Réceptacles de capacité variable
• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides

Abrégé

The invention relates to a biopharmaceutical container comprising: a connector to be secured to a chamber connector; a bag serving as a receptacle, one part of which is secured to the connector; and a flexible tube tucked inside the bag, which tube can extend out from the bag through the connector. The biopharmaceutical container, wherein: the tube forms part of the bag, the tube is a neck of reduced size extending from the body of the bag, and the aforementioned part of the bag that is secured to the connector is a fold in the wall of the bag, said wall of the bag forming the body of the bag on one side of the fold and the tube on the other side of the fold.

Classes IPC  ?

• A61J 1/10 - Récipients du type sac
• B29L 31/00 - Autres objets particuliers
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• A61M 39/10 - Raccords ou accouplements pour tubes

Abrégé

The invention relates to a 3D flexible pouch to be filled with a biopharmaceutical product, produced by assembling two wall elements and two gussets. At least one connection port can be provided for filling and/or emptying. A substantially parallelepipedic configuration is obtained in a filled state by unfolding the gussets and folding the flaps of the two wall elements. A welded seam is produced in a join portion formed at one end and cut out in a V shape, so as to directly connect the two wall elements. In a substantially flat configuration of the empty flexible pouch, the join portion projects axially outwards in relation to the gussets and is defined by two edges which are oblique in relation to a longitudinal axis of said pouch.

Classes IPC  ?

• A61J 1/10 - Récipients du type sac
• B65B 3/04 - Procédés ou moyens pour charger le matériau dans les réceptacles ou récipients
• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides

Abrégé

A 3-D flexible bag to be filled with a biopharmaceutical product is formed by assembling of two wall elements and two gussets. At least one connection port is provided, for filling and/or emptying. A substantially parallelepipedal configuration is obtained in a filled state thanks to the unfolding of the gussets combined with the folding of flaps of the two wall elements. A transverse weld, formed at one end, connects the two wall elements of the bag and extends continuously, keeping in a folded-flat state: an elongate edge portion of one gusset; an elongate edge portion of the other gusset. This transverse weld has a length corresponding to a determined dimension of the flexible bag in the parallelepipedal configuration.

Classes IPC  ?

• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
• A61J 1/10 - Récipients du type sac
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• B65D 30/20 - Sacs, sachets ou réceptacles analogues caractérisés par leur forme ou leur conception comportant des plis, p. ex. pour faciliter le repliage

Produits et services

Growing media; Growing media for use in the biotechnological and biopharmaceutical sector; Reagents for scientific, industrial and research purposes; Growing media for scientific, laboratory and industrial use; buffers [chemicals]; buffers for use in the biotechnological and biopharmaceutical sector. Culture media for medical (human) and veterinary use; culture media for mammalian, insect and bacteriological cultures; growing media for medical or veterinary use; Reagents for medical use buffers for medical or veterinary use. Scientific research services, scientific laboratory services, scientific research and development, research and development in the field of pharmaceuticals and biotechnology.

Abrégé

A port is suitable for attachment to a container and suitable for being traversed by a needle used to transfer content between the inside of the container and the outside of the container, and includes a rigid annular body extending in a direction including a side wall surrounding a channel extending between an inner end and an outer end, the inner and outer ends being at opposite ends along the direction, the body being open at the ends, an overmolding member of thermoplastic elastomer including a sealing portion suitable for being traversed by the needle in a direction close to the direction, the needle passing through the inner and outer ends, the overmolding member sealing the channel in a fluidtight manner after withdrawal of a needle and further including an adhesion portion suitable for attaching the port to the container.

Classes IPC  ?

• A61J 1/10 - Récipients du type sac
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• A61J 1/20 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue
• A61M 39/00 - Tubes, raccords ou accouplements pour tubes, soupapes, voies d'accès ou similaires, spécialement adaptés pour un usage médical
• A61M 39/04 - Voies d'accès avec des éléments perforables auto-obturants
• B29C 70/68 - Façonnage de matières composites, c.-à-d. de matières plastiques comprenant des renforcements, des matières de remplissage ou des parties préformées, p. ex. des inserts en incorporant ou en surmoulant des parties préformées, p. ex. des inserts ou des couches
• B29L 31/00 - Autres objets particuliers

Abrégé

Disclosed is a container for transporting a biopharmaceutical fluid, the container including a leak-tight wall having an outer portion and an inner portion, the outer portion and the inner portion delimiting between them an intermediate space that may be inflated under pressure with an inflation gas, the container being adapted to be alternately in: a non-inflated state in which the container is empty of pressurized inflation gas; an inflated state in which the wall of the container is inflated and delimits an internal cavity adapted to contain the biopharmaceutical fluid. The wall includes a peripheral lateral wall around the internal cavity, the peripheral lateral wall being completely rigid or semi-rigid when the container is in the inflated state so as to ensure a protection of the biopharmaceutical fluid.

Classes IPC  ?

• B65D 81/03 - Enveloppes ou emballages souples avec des propriétés d'amortissement des chocs, p. ex. feuilles avec des bulles incorporées
• A01N 1/02 - Conservation de parties vivantes
• B01F 3/04 - Mélange, p.ex. dispersion, émulsion, selon les phases à mélanger de gaz ou de vapeurs avec des liquides
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• B01F 15/00 - Accessoires pour mélangeurs
• B01F 7/00 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins

Abrégé

A method for assembling a mixer-container intended for receiving a biopharmaceutical fluid includes providing a container with a mixing device including at least one shaft having an adjustable length, and at least one first bearing attached to a wall of the container, the shaft extending at least into the inner space from the first bearing; a rigid outer device that compresses the container; and a drive motor located outside the container, the first bearing of the container is placed so as to be spaced apart from the motor, and the length of the shaft is adjusted along the main axis by arranging the shaft opposite the motor to enable the motor to rotate the shaft.

Classes IPC  ?

• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
• B01F 7/16 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins avec agitateurs tournant autour d'un axe vertical
• B01F 15/00 - Accessoires pour mélangeurs
• B01F 13/08 - Mélangeurs magnétiques
• B01F 7/00 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins
• B01F 7/22 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins avec agitateurs tournant autour d'un axe vertical à hélices
• B01F 3/04 - Mélange, p.ex. dispersion, émulsion, selon les phases à mélanger de gaz ou de vapeurs avec des liquides
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie

Abrégé

Disclosed is a bag including: a first envelope having at least one fill and/or discharge orifice for a biopharmaceutical fluid and a fill and/or discharge tube associated in a fluidtight manner with the fill and/or discharge orifice, a second envelope within which the first envelope is located, and a spacer element. The first envelope, the second envelope, and the spacer element form a coherent whole, in particular during use of the bag, and the fill and/or discharge tube traverses the second envelope by a fluidtight connection, the fill and/or discharge inlet being located outside the second envelope.

Classes IPC  ?

• G01M 3/32 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par mesure du taux de perte ou de gain d'un fluide, p. ex. avec des dispositifs réagissant à la pression, avec des indicateurs de débit pour récipients, p. ex. radiateurs
• A61J 1/10 - Récipients du type sac
• G01M 3/22 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs pour tuyaux, câbles ou tubesExamen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs pour raccords ou étanchéité de tuyauxExamen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs pour soupapes
• A61J 1/18 - Dispositions pour indiquer l'état, p. ex. l'état stérile, du contenu du récipient
• G01M 3/02 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• A61J 1/20 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue
• B65D 30/08 - Sacs, sachets ou réceptacles analogues caractérisés par le matériau utilisé à parois stratifiées ou multiples en relation de vis-à-vis, p. ex. à double paroi
• B65D 30/20 - Sacs, sachets ou réceptacles analogues caractérisés par leur forme ou leur conception comportant des plis, p. ex. pour faciliter le repliage
• B65D 77/04 - Objets ou matériaux enfermés dans plusieurs réceptacles disposés les uns dans les autres

Abrégé

Disclosed is a device for transporting a biopharmaceutical fluid, including an inner bag forming an inner chamber adapted and intended for receiving a biopharmaceutical fluid, an outer container including an outer receptacle, the outer receptacle including a wall forming an outer chamber, an expandable protective element arranged at least partially between the outer receptacle and the inner bag and adapted to receive the inner bag, the expandable protective element being adapted to expand in volume to an expanded state so as to be interposed between the outer receptacle and the inner bag, the expandable protective element in the expanded state surrounding the inner bag and filling the space between the wall of the outer receptacle and the inner bag.

Classes IPC  ?

• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
• B65D 81/05 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu spécialement adaptés pour protéger leur contenu des dommages mécaniques maintenant le contenu en position éloignée des parois de l'emballage ou des autres pièces du contenu
• A61J 1/05 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour recueillir, stocker ou administrer du sang, du plasma ou des liquides à usage médical
• B65D 3/02 - Réceptacles rigides ou semi-rigides ayant un corps ou des parois périphériques de section transversale courbe ou partiellement courbe, réalisés en enroulant ou courbant du papier sans plier selon des lignes définies caractérisés par la forme
• B65D 35/08 - Structure du corps en une seule pièce en plastique
• B65D 35/26 - Réceptacles pliables, de forme tubulaire, conçus de telle sorte que l'expulsion de leur contenu leur donne une déformation permanente, p. ex. tubes souples pour dentifrice ou autres produits plastiques ou semi-liquidesSupports adéquats avec dispositifs accessoires pour le remplissage
• B65D 35/28 - Réceptacles pliables, de forme tubulaire, conçus de telle sorte que l'expulsion de leur contenu leur donne une déformation permanente, p. ex. tubes souples pour dentifrice ou autres produits plastiques ou semi-liquidesSupports adéquats avec dispositifs accessoires pour expulser les contenus

Abrégé

Disclosed is a fluid connection system including a sleeve, a pipe and a fluid connector, the fluid connector including at least one rigid body made from a sterilizable biocompatible material, and the pipe including a flexible connection portion made from a sterilizable biocompatible material that is at least partially elastomeric. The fluid connector and the flexible connection portion of the pipe are assembled to one another, with the flexible connection portion of the pipe surrounding the rigid body, and the sleeve being shrunk tightly, but with free movement, on the pipe.

Classes IPC  ?

• F16L 13/00 - Raccords de tuyaux non démontables, p. ex. raccords soudés, collés ou matés
• F16L 47/22 - Raccordements ou autres accessoires de raccordement spécialement adaptés pour être en matières plastiques ou pour être utilisés avec des tuyaux en matières plastiques basés principalement sur les propriétés spécifiques des matières plastiques utilisant un matériau se rétractant
• A61M 39/00 - Tubes, raccords ou accouplements pour tubes, soupapes, voies d'accès ou similaires, spécialement adaptés pour un usage médical
• A61M 39/16 - Raccords ou accouplements pour tubes avec des dispositions pour la désinfection ou la stérilisation
• A61M 39/10 - Raccords ou accouplements pour tubes
• F16L 33/22 - Dispositions d'assemblage des manches avec des organes rigidesRaccords rigides pour manches, p. ex. éléments unitaires s'engageant à la fois dans deux manches avec moyens non mentionnés dans les groupes précédents pour saisir la manche entre l'extérieur et l'intérieur
• A61M 39/12 - Raccords ou accouplements pour tubes pour raccorder un tube flexible à un dispositif de fixation rigide
• F16L 33/207 - Segments, manchons ou autres organes d'une seule pièce enserrant la manche ou dilatés à l'intérieur de la manche au moyen d'outilsAgencements utilisant de tels organes avec uniquement un manchon contracté sur la manche
• F16L 33/30 - Dispositions d'assemblage des manches avec des organes rigidesRaccords rigides pour manches, p. ex. éléments unitaires s'engageant à la fois dans deux manches comprenant uniquement des pièces disposées à l'intérieur des manches

Abrégé

A fluid connection set includes a connector (1), a flexible hose (2), and a crimping collar (5) for fixing the front end of the flexible hose to the connector, the connector including a connector body (10), a tubular nozzle (3), the tubular nozzle including retaining radial projections (31) of the hose as well as a clamping area (30) of the hose, and a temporary accommodation space (4), arranged between the tubular nozzle (3) and the connector body (10), for housing the collar during the operation of inserting the flexible tube, after which the collar is moved with respect to the clamping area and then crimped.

Classes IPC  ?

• F16L 13/14 - Raccords de tuyaux non démontables, p. ex. raccords soudés, collés ou matés réalisés par déformation plastique du matériau du tuyau, p. ex. par déformation des brides, par laminage
• F16L 33/207 - Segments, manchons ou autres organes d'une seule pièce enserrant la manche ou dilatés à l'intérieur de la manche au moyen d'outilsAgencements utilisant de tels organes avec uniquement un manchon contracté sur la manche
• F16L 33/22 - Dispositions d'assemblage des manches avec des organes rigidesRaccords rigides pour manches, p. ex. éléments unitaires s'engageant à la fois dans deux manches avec moyens non mentionnés dans les groupes précédents pour saisir la manche entre l'extérieur et l'intérieur

Abrégé

A female connector (1) configured to receive a male connector (2), having an annular exterior retaining rim (24), the female connector including a body (10), and a transverse slide (4) forming a housing, the housing (4) including two lateral grooves (41,42), the female connector including a separate deformable locking ring (3) capable of being inserted in the housing and of locking the male connector in the coupling position, the locking ring including two first concave arched portions (31), as viewed from the axis, and two second arched portions (32), with inverse curvature, i.e. convex when viewed from the axis, the second arched portions being capable of flexing towards the exterior during insertion of the male connector and capable of abutting on the external annular retaining rim and preventing withdrawal of the male connector, whereby after locking of the male connector in the female connector a definitive locking is obtained.

Classes IPC  ?

• F16L 37/084 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique
• F16B 21/18 - Dispositifs sans filetage pour empêcher le mouvement relatif selon l'axe d'une broche, d'un ergot, d'un arbre ou d'une pièce analogue par rapport à l'organe qui l'entoureFixations à ergots et douilles largables sans filetage à parties séparées par gorges ou encoches pratiquées dans l'axe ou l'arbre et avec bague annulaire formant ressort insérée dans la gorge (circlip) ou autre dispositif élastique de fixation du même genreDispositifs sans filetage pour empêcher le mouvement relatif selon l'axe d'une broche, d'un ergot, d'un arbre ou d'une pièce analogue par rapport à l'organe qui l'entoureFixations à ergots et douilles largables sans filetage à parties séparées par gorges ou encoches pratiquées dans l'axe ou l'arbre Détails

Abrégé

A modular fluid connection assembly includes a female connector (1) for fluid connection, provided to receive a male connector (2) having an external annular retaining rim (24), the female connector including a body (10) with an axial bore X, and a slide forming a transverse housing (4), the housing (4) including two parallel lateral grooves (41, 42) and the housing opening at at least one of its ends (40) along the direction of the slide Z, the assembly including a non-unlocking locking element (3), in the form of a deformable locking ring (3), the assembly including an unlocking locking element (5), in the form of a locking slider (5), in which the female connector is configured to receive equally either a non-unlocking element, or an unlocking element.

Classes IPC  ?

• F16L 37/084 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique

Abrégé

Female connector for accepting a male connector having a retaining external annular rim, a slot including two parallel lateral grooves and the slot opening at least at one of its ends forming a mouth of the housing, the female connector including a locking slide distinct from the body, movable between a locking position and an unlocking position, the locking slide including a locking plate and an actuating knob formed integrally with the plate, with a retaining portion belonging to the locking plate to come into abutment against the retaining outer annular rim, the locking slide including at least one flexible tab formed integrally, returning the slide toward the first position, the flexible tab pressing on each side of the mouth in the axial direction X so that the return force is balanced about X and creates no torque that could have a tendency to cause the locking plate to jam.

Classes IPC  ?

• F16L 37/00 - Accouplements du type à action rapide
• F16L 37/08 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage
• F16L 37/084 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique
• F16L 37/088 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique au moyen d'un segment élastique fendu

Abrégé

Disclosed is a fluid-connection device for connecting a first wall defining a first fluid space, for example a flexible pipe, to a second wall defining a second fluid space, in the form of a flexible pipe or enclosure, including a first male connector, the first connector including a seal and a snap-fitting collar, the seal extending radially prior to coupling from the axis until a first radial distance R1, a second female connector capable of receiving the first connector, the second connector including at least one flexible tab with one end against which the locking collar abuts in coupling position, in order to prevent retraction from the coupling position, the flexible tab being defined relative to the axis between a second radial distance R2 and a third radial distance R3, which is greater than the second radial distance R2, wherein R2>R1.

Classes IPC  ?

• F16L 37/098 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique au moyen de crochets flexibles
• A61M 39/10 - Raccords ou accouplements pour tubes
• F16L 33/025 - Colliers de serrage pour manches serrés par déformation de boucles ou de plis s'étendant radialement
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet

Abrégé

A container for ensuring the transport and the aseptic transfer of a biopharmaceutical product from or to a closed chamber provided with a leaktight joining device, includes: an annular flange delimiting an opening, a removable cover, built-in elements for locking/unlocking the removable cover and a peripheral envelope. The built-in locking/unlocking elements include a built-in functional locking/unlocking arrangement formed by a through-housing formed in the annular flange and a blind housing formed in the removable cover, and by a pin at an inner radial position and a pin at an outer radial position. The container is capable of being in an initial locking position, in an intermediate unlocking position and in a final locking position owing to the displacements of the pin at an inner radial position and the pin at an outer radial position in the blind hole of the removable cover and in the through-housing of the annular flange.

Classes IPC  ?

• B01L 1/02 - Chambres pressuriséesLeurs sas
• G21F 7/005 - Passages blindés à travers les paroisVerrouillagesDispositifs de transfert entre chambres
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• B65B 7/16 - Fermeture de réceptacles ou récipients semi-rigides ou rigides, non déformés par le contenu ou n'en prenant pas la forme, p. ex. boîtes ou cartons

Abrégé

a) into the housing, when the filling state is sufficiently advanced. The causes of poor deployment of the pouch are thus minimized, without human intervention.

Classes IPC  ?

• B65B 3/04 - Procédés ou moyens pour charger le matériau dans les réceptacles ou récipients
• A61J 1/10 - Récipients du type sac
• B65B 61/20 - Dispositifs accessoires, non prévus ailleurs, opérant sur feuilles, flans, bandes, attaches, réceptacles ou paquets pour ajouter des cartes, des coupons ou d'autres encarts au contenu
• B65B 67/12 - Supports de sacs, c.-à-d. bâtis ou châssis avec dispositifs pour tenir les sacs en position ouverte afin de faciliter l'ensachage des objets ou matériaux

Produits et services

Containers of metal for transporting flexible bags for biological, medical or pharmaceutical liquids.

Abrégé

Fluid-connection device for connecting a flexible pipe defining a first fluid space to a second flexible pipe or a flexible fluid enclosure in a biopharmaceutical assembly, includes a first connector and a second connector equivalent thereto, the first connector and second connector adapted to be coupled together in a genderless manner, by an insertion movement that is essentially an axial translation, into a relative coupling position, which defines a mating plane, each of the connectors including, in an alternating manner along the circumferential direction, N flexible snap-fitting tabs and N stop surfaces, the flexible snap-fitting tabs projecting axially forwards relative to the mating plane, and the stop surfaces being set back from the mating plane so that, in the coupling position, the snap-fitting tabs of one connector clip into place on the stop surfaces of the other connector, such that the resulting position is locked by the snap-fitting tabs.

Classes IPC  ?

• F16L 37/098 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique au moyen de crochets flexibles
• A61M 39/10 - Raccords ou accouplements pour tubes
• A61M 39/18 - Procédés ou appareils pour réaliser les connexions sous conditions stériles
• F16L 33/025 - Colliers de serrage pour manches serrés par déformation de boucles ou de plis s'étendant radialement
• A61M 39/16 - Raccords ou accouplements pour tubes avec des dispositions pour la désinfection ou la stérilisation
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet

Abrégé

a) of the nozzle, an abutment clamp (16), a connection interface (6), a separate ring (2), axially movable between an inoperative position and an operative position, for covering the flexible tabs (3) such as to push same radially inward in order to press the pipe onto the nozzle in the operative position, the tabs extending substantially parallel to the axis (A) when the ring (2) is in the operative position.

Classes IPC  ?

• F16L 33/22 - Dispositions d'assemblage des manches avec des organes rigidesRaccords rigides pour manches, p. ex. éléments unitaires s'engageant à la fois dans deux manches avec moyens non mentionnés dans les groupes précédents pour saisir la manche entre l'extérieur et l'intérieur
• A61M 39/10 - Raccords ou accouplements pour tubes
• A61M 39/12 - Raccords ou accouplements pour tubes pour raccorder un tube flexible à un dispositif de fixation rigide
• F16L 37/098 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique au moyen de crochets flexibles
• A61J 1/20 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet

Abrégé

A fluid-connection device capable of and intended for connecting a flexible pipe to a flexible or rigid pipe or enclosure in a biopharmaceutical assembly such as to provide fluid communication between two fluid spaces, including a first connector in fluid communication with the first fluid space, a second connector in fluid communication with the second fluid space, the first connector and the second connector optionally being coupled together in a coupling position, the first connector including a tubular nozzle which can be inserted in one end of the pipe, a pipe clamp being arranged around the end of the tube in order to clamp the pipe onto the tubular nozzle of the first connector, the second connector including protection elements which, in the coupling position, are positioned radially at least partially opposite the pipe clamp, whereby the pipe clamp cannot come into direct contact with external elements.

Classes IPC  ?

• F16L 33/025 - Colliers de serrage pour manches serrés par déformation de boucles ou de plis s'étendant radialement
• A61M 39/28 - Moyens de serrage pour l'écrasement des tubes flexibles, p. ex. brides de serrage à rouleaux
• A61M 39/10 - Raccords ou accouplements pour tubes
• F16L 33/22 - Dispositions d'assemblage des manches avec des organes rigidesRaccords rigides pour manches, p. ex. éléments unitaires s'engageant à la fois dans deux manches avec moyens non mentionnés dans les groupes précédents pour saisir la manche entre l'extérieur et l'intérieur
• F16L 37/098 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique au moyen de crochets flexibles
• A61M 39/12 - Raccords ou accouplements pour tubes pour raccorder un tube flexible à un dispositif de fixation rigide
• F16L 37/084 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet

Abrégé

Disclosed is a fluid-connection device for connecting a first wall defining a first fluid space, in the form of a flexible pipe, to a second wall defining a second fluid space, in the form of a flexible or rigid disposable pipe or enclosure, in a biopharmaceutical assembly, including a first connector in fluid communication with the first space, the first connector including a tubular nozzle for receiving the pipe by insertion along the axis A, a pipe clamp arranged around the end of the pipe in order to clamp the pipe onto the tubular nozzle of the first connector, a protective cover forming a separate part, capable of being snap-fit in an operative position in which the cover is at least partially surrounding the first connector and the pipe clamp thereof, by way of which the pipe clamp cannot come into direct contact with external elements.

Classes IPC  ?

• F16L 37/08 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage
• A61M 39/10 - Raccords ou accouplements pour tubes
• F16L 33/22 - Dispositions d'assemblage des manches avec des organes rigidesRaccords rigides pour manches, p. ex. éléments unitaires s'engageant à la fois dans deux manches avec moyens non mentionnés dans les groupes précédents pour saisir la manche entre l'extérieur et l'intérieur
• F16L 37/098 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique au moyen de crochets flexibles
• F16L 33/025 - Colliers de serrage pour manches serrés par déformation de boucles ou de plis s'étendant radialement
• A61M 39/12 - Raccords ou accouplements pour tubes pour raccorder un tube flexible à un dispositif de fixation rigide
• F16L 33/02 - Colliers de serrage pour manches
• F16L 57/00 - Protection des tuyaux ou d'objets de forme similaire contre les dommages ou les usures internes ou externes
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet

Abrégé

A frame delimits an inside space and includes a peripherally closed side wall and two transverse openings or one transverse opening and a transverse end wall. It is capable of allowing the airtight engagement of the open free edge of a side wall in film form of a receptacle that is at least partially deformable. It is specially designed for the creation of a 3D container. The frame is also able to act as a support for at least one functional port or attachment port of a functional element. Its axial size is adequate for delimiting a space of a size that is at least equal to the axial dimension of the functional element, so that the latter can be completely housed within the inside space.

Classes IPC  ?

• B01F 7/16 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins avec agitateurs tournant autour d'un axe vertical
• B01F 15/00 - Accessoires pour mélangeurs
• A61J 1/05 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour recueillir, stocker ou administrer du sang, du plasma ou des liquides à usage médical
• B65D 21/08 - Réceptacles de capacité variable
• B65D 37/00 - Réceptacles flexibles transportables non prévus ailleurs
• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
• B65D 88/16 - Grands réceptacles souples
• B65D 88/68 - Grands réceptacles caractérisés par des moyens pour faciliter le remplissage ou le vidage en empêchant la formation de ponts par des dispositifs en rotation
• B65D 90/20 - Cadres ou filets, p. ex. pour réceptacles souples

Abrégé

The container includes a lower wall and an erect side wall limiting an upper opening of a housing for accommodating a flexible pouch containing a fluid; containment elements including a containment wall, the gap between its peripheral edge and the side wall being limited; the containment wall adapted to be applied against the pouch and held fixed in this position by holding elements arranged in the container and borne by the containment elements by a structural and functional combination, and being movable between an inactive retracted state and an active expanded state, in which a distal end part is either moved away from the side wall or applied there against without any chance of sliding; and adapted to be applied at any desired location of a zone of the side wall such that the containment wall can be applied and held against the pouch regardless of how full the latter is.

Classes IPC  ?

• B65D 77/00 - Paquets réalisés en enfermant des objets ou des matériaux dans des réceptacles préformés, p. ex. des boîtes, des cartons, des sacs ou des sachets
• B65D 77/02 - Objets enveloppés enfermés dans des réceptacles rigides ou semi-rigides
• B65D 77/04 - Objets ou matériaux enfermés dans plusieurs réceptacles disposés les uns dans les autres
• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
• B65D 88/60 - Grands réceptacles caractérisés par des moyens pour faciliter le remplissage ou le vidage par déplacement de parois de parois internes
• B65D 90/04 - Garnitures internes
• B65D 90/00 - Parties constitutives, détails ou accessoires des grands réceptacles
• B65D 85/68 - Réceptacles, éléments d'emballage ou paquets spécialement adaptés à des objets ou à des matériaux particuliers pour machines, moteurs ou véhicules assemblés ou en pièces détachées
• A61J 1/05 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour recueillir, stocker ou administrer du sang, du plasma ou des liquides à usage médical
• B65B 3/00 - Emballage de matériaux plastiques, de semi-liquides, de liquides ou de liquides et solides mélangés, dans des réceptacles ou récipients individuels, p. ex. dans des sacs ou sachets, boîtes, cartons, bidons ou pots
• B65B 7/02 - Fermeture des réceptacles ou récipients déformés par le contenu ou en prenant la forme, p. ex. sacs

Abrégé

A fluid connection device (10) for connecting two fluid conduits (11, 12), includes a female plug (1), a male plug (2), intended to be inserted into the female plug into a final coupling position, a movable primary locking device (3), having a locked position (30) in which it prevents the male and female plugs from being released from the final coupling position, and a movable secondary latch (4) having an active position (40) designed to prevent the primary locking device (3) from being moved out of the locked position of same, whereby the fluid connection device can establish a permanent connection of the first and second conduits.

Classes IPC  ?

• F16L 37/098 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique au moyen de crochets flexibles
• A61M 39/10 - Raccords ou accouplements pour tubes
• F16L 37/084 - Accouplements du type à action rapide dans lesquels l'assemblage entre les extrémités s'aboutant ou se chevauchant est maintenu par des organes de blocage combinés à un verrouillage automatique
• F16L 21/08 - Raccords avec manchon ou douille avec moyens additionnels de verrouillage

Abrégé

Device for receiving and draining a high quantity of biopharmaceutical fluid under pressure includes an inner bag, having an inner container for receiving the fluid and provided with a filling port, a drain port, a filling tube having a filling inlet for connection to a filling line, a drain tube having a drain outlet for connection to a drain line, an outer container in which the bag is placed, a compression chamber between the outer container and the bag, an injection port for injecting pressurized draining gas into the chamber, sealed bushings passing through the container via the filling and drain tubes, the deformation capacities of the bag and container being such that, when the draining gas is injected into the chamber, the bag is compressed and the biopharmaceutical fluid is emptied. The outer container includes a receptacle forming the outer chamber, the tubes passing therethrough via permanently fixed connections.

Classes IPC  ?

• A61M 5/148 - Perfusion sous pression, p. ex. utilisant des pompes utilisant des réservoirs sous pression, p. ex. au moyen de pistons flexibles
• A61J 1/10 - Récipients du type sac
• B67D 7/02 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail pour transférer des liquides autres que des carburants ou des lubrifiants
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
• B65D 33/01 - Ventilation ou drainage des sacs

Abrégé

A pouch includes: a first closed, inner casing, made of at least one non-porous plastic material with a high-capacity gas barrier, delimiting a first space, forming a pouch stricto sensu for accommodating a biopharmaceutical product or device, a second closed, outer casing, made of at least one non-porous plastic material with a high-capacity gas barrier, delimiting a second space in which the pouch stricto sensu is located, spacer elements, at least one selected tracer gas, located in the first or second space outside of the pouch stricto sensu, with a higher partial pressure than in the second space outside of the pouch stricto sensu or in the first space, at least one colorimetric detector located, respectively, in the second space outside of the pouch stricto sensu or in the first space responsive to the concentration of the tracer gas, by switching from a first color to a second different color.

Classes IPC  ?

• B65D 75/38 - Objets ou matériaux enveloppés dans deux enveloppes ou plus, disposées l'une dans l'autre
• B65D 77/04 - Objets ou matériaux enfermés dans plusieurs réceptacles disposés les uns dans les autres
• B65D 79/02 - Arrangements ou dispositifs pour indiquer un stockage ou un transport incorrects
• B65D 81/20 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu fournissant une ambiance spécifique pour le contenu, p. ex. température supérieure ou inférieure à la température ambiante sous vide ou pression superatmosphérique ou en atmosphère spéciale, p. ex. sous gaz inerte
• B65B 31/02 - Remplissage, fermeture, ou remplissage et fermeture, de réceptacles dans des chambres maintenues en dépression ou en surpression ou contenant une atmosphère spéciale, p. ex. du gaz inerte
• G01N 31/22 - Utilisation des réactifs chimiques

Abrégé

3, the contact layer including less than 0.10 wt %, preferably less than 0.07 wt %, of additives able to release a degradation compound further to gamma irradiation in the range of 25 kGy-50 kGy that can slow down or delay cellular growth. The process for manufacturing such a film, as well as the single-use pouch manufactured from that film are also described.

Classes IPC  ?

• B32B 1/02 - Réceptacles, p.ex. réservoirs
• B32B 27/18 - Produits stratifiés composés essentiellement de résine synthétique caractérisée par l'emploi d'additifs particuliers
• B32B 27/30 - Produits stratifiés composés essentiellement de résine synthétique comprenant une résine vinyliqueProduits stratifiés composés essentiellement de résine synthétique comprenant une résine acrylique
• B32B 27/32 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyoléfines
• B65D 81/26 - Adaptations pour empêcher la détérioration ou l'altération du contenuApplications au réceptacle ou au matériau d'emballage d'agents de conservation des aliments, de fongicides, d'insecticides ou de produits repoussant les animaux avec dispositifs pour évacuer ou absorber les fluides, p. ex. s'écoulant du contenuEmploi de produits empêchant la corrosion ou de dessiccateurs
• C08K 5/526 - Esters des acides phosphoreux, p. ex. de H3PO3 avec des composés hydroxyaryliques
• C08L 23/08 - Copolymères de l'éthylène

Abrégé

A multilayer film includes a contact layer, a core layer, and an outer layer, the contact and core layers being integral with a first tie layer; and the outer and core layers being integral with a second tie layer; the contact layer includes a copolymer of ethylene and α-olefin having a density from 0.870 to 0.910 g/cm3, alone or in mixture with a polyolefin having a density from 0.910 to 0.940 g/cm3; the core layer includes a flex-crack resistant ethylene vinyl alcohol copolymer having an ethylene content from 25 to 48 mol % or a mixture of an ethylene vinyl alcohol copolymer having an ethylene content from 25 to 48 mol %, and an ionomer acid ethylene copolymer; the outer layer includes a polyolefin having a density from 0.910 to 0.940 g/cm3, alone or in mixture with a copolymer of ethylene and α-olefin having a density from 0.870 to 0.910 g/cm3.

Classes IPC  ?

• B32B 27/08 - Produits stratifiés composés essentiellement de résine synthétique comme seul composant ou composant principal d'une couche adjacente à une autre couche d'une substance spécifique d'une résine synthétique d'une sorte différente
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• B32B 7/02 - Propriétés physiques, chimiques ou physicochimiques
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• B32B 27/30 - Produits stratifiés composés essentiellement de résine synthétique comprenant une résine vinyliqueProduits stratifiés composés essentiellement de résine synthétique comprenant une résine acrylique
• B32B 27/32 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyoléfines

Produits et services

Media for cell culture for the biotechnology and biopharmaceutical sector. Scientific research services, scientific laboratory services, scientific research and development, research and development in the field of pharmaceuticals and biotechnology.

Abrégé

A sterile individual set for use in a process of manufacturing a biopharmaceutical product. To make it quicker and easier to grasp and use fluidic type functional members, the sterile individual set includes a sterile flexible bag having a peripheral wall defining a sterile internal space and a fluidic type functional member arranged at least partially inside the sterile internal space. The functional member includes one or more communication duct(s) arranged in the sterile internal space. The sterile individual set also includes structural association elements capable of holding together several portions of the communication duct or ducts that are to be bundled together into a bundle. The structural association elements have an external surface with lower static and dynamic friction coefficients so as to make the functional member easier to handle by slippage of the bundle of communication ducts with respect to the peripheral wall of the flexible bag.

Classes IPC  ?

• B65B 5/06 - Emballage de groupes d'objets, chaque groupe étant traité comme un seul objet
• B65B 13/02 - Application et amarrage des matériaux de liage, p. ex. ficelles, fils métalliques, bandelettes, bandes ou rubans, autour d'objets ou de groupes d'objets
• B65B 69/00 - Déballage des objets ou matériaux non prévu ailleurs
• B65B 5/04 - Emballage d'objets séparés
• B65D 63/10 - Courroies, rubans ou bandes non métalliquesÉléments filamenteux, p. ex. cordons, fils ou fils métalliquesJonctions de leurs extrémités
• H02G 3/04 - Tubes ou conduits de protection, p. ex. échelles à câbles ou goulottes de câblage
• B65B 9/00 - Enserrage d'objets les uns à la suite des autres ou de quantités de matériaux, p. ex. liquides ou semi-liquides, dans des bandes plates, pliées ou tubulaires faites de feuilles en matière soupleDivision des tubes flexibles remplis pour former des paquets

Produits et services

Media for cell culture for use in the biotechnological and biopharmaceutical industry. Scientific research services, scientific laboratory services, scientific research and development, research and development in the pharmaceutical and biotechnological fields.

Abrégé

A processing receptacle for a biopharmaceutical product includes a pocket configured to accommodate the biopharmaceutical product that can assume a flat-folded state, an expanded state, or any intermediate state in between, a processing element having an active inner portion, a rigid protective chamber to protect the processing element, and at least one opening for introducing the product into the receptacle and/or for draining the contents from the receptacle. A portion of the protective chamber is rigidly attached to a portion of the pocket and movement of the pocket up or down brings about movement of the protective chamber; the processing element and the protective chamber are arranged to be independent from one another relative to their movements. The protective chamber has a variable height that automatically adapts to accommodate the flat-folded, expanded, or intermediate state of the pocket, and in each state of the pocket, the processing element is offset from the side walls and the upper end portion of the pocket, while being adjacent to the lower end portion. A device having such a processing receptacle and a method for processing a biopharmaceutical product utilizing such a device are also presented.

Classes IPC  ?

• B01F 7/16 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins avec agitateurs tournant autour d'un axe vertical
• B01F 15/00 - Accessoires pour mélangeurs
• B65D 83/00 - Réceptacles ou paquets comportant des moyens particuliers pour distribuer leur contenu
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• C12M 1/06 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'introduction de gaz avec agitateur, p. ex. avec agitateur à turbine

Abrégé

A container (10) for receiving biopharmaceutical content (C) in liquid, fluid or gaseous form, includes a peripheral wall (12) that is closed on itself, at least one transfer pipe (22), at least one guiding element (30; 130), and wherein the at least one guiding element (30; 130) includes a gripping member (32; 132) and an attachment member (44; 144). The gripping member (32; 132) and the attachment member (44; 144) are structurally separate and independent of one another and the guiding element (30; 130) has reciprocal assembly elements (60; 160) allowing the structural or functional assembly of the gripping member (32; 132) with the attachment member (44; 144) to ensure the positioning of the gripping member (32; 132) close to the attachment member (44; 144) and the connecting area (46; 146) of the corresponding peripheral wall (12).

Classes IPC  ?

• B65D 88/54 - Grands réceptacles caractérisés par des moyens pour faciliter le remplissage ou le vidage
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie

Abrégé

A leaktight joining device for ensuring the aseptic transfer of a biopharmaceutical product between a chamber equipped with a removable door and a container equipped with a removable cover, includes: stationary temporary flanging elements, stationary unlocking elements capable of changing the container from an initial locking position to an intermediate unlocking position so as to ensure an aseptic communication between the container and the chamber, stationary locking element capable of changing the container from the intermediate locking position to a final locking position, an annular functional ring gear capable of actuating the stationary unlocking elements and the stationary locking elements of the container. The stationary temporary flanging elements, the stationary unlocking elements, and the stationary locking elements are mechanically linked to the annular functional ring gear and arranged so that the unidirectional rotation of the annular functional ring gear about the geometric axis of rotation successively drives the actuation thereof.

Classes IPC  ?

• B01L 1/02 - Chambres pressuriséesLeurs sas
• G21F 7/005 - Passages blindés à travers les paroisVerrouillagesDispositifs de transfert entre chambres
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse

Abrégé

A container for ensuring the transport and the aseptic transfer of a biopharmaceutical product from or to a closed chamber provided with a leaktight joining device, includes: an annular flange delimiting an opening, a removable cover, built-in elements for locking/unlocking the removable cover and a peripheral envelope. The built-in locking/unlocking elements include a built-in functional locking/unlocking arrangement formed by a through-housing formed in the annular flange and a blind housing formed in the removable cover, and by a pin at an inner radial position and a pin at an outer radial position. The container is capable of being in an initial locking position, in an intermediate unlocking position and in a final locking position owing to the displacements of the pin at an inner radial position and the pin at an outer radial position in the blind hole of the removable cover and in the through-housing of the annular flange.

Classes IPC  ?

• B01L 1/02 - Chambres pressuriséesLeurs sas
• G21F 7/005 - Passages blindés à travers les paroisVerrouillagesDispositifs de transfert entre chambres
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse

Abrégé

The valve includes a female part having a closed, transverse, proximal end wall, and a tubular wall integral with a flange part, a lateral opening being formed on the proximal section of the tubular wall, a male part having a tubular wall forming, on the proximal side, a closing/opening part having an open, transverse, proximal end; the closing/opening part has an external shape and an external dimension that fit the internal shape and internal dimension of the proximal receiving part of the female part. The sealing elements include three ring seals separated from one another in an axial direction, supported by the upper surface of the tubular wall of the male part and engaging with the female part, a proximal seal to the fluid product, a distal seal to external contaminants, and an intermediate seal to the fluid product and to external contaminants between the proximal and distal seals.

Classes IPC  ?

• F16K 3/26 - Robinets-vannes ou tiroirs, c.-à-d. dispositifs obturateurs dont l'élément de fermeture glisse le long d'un siège pour l'ouverture ou la fermeture à faces d'obturation en forme de surfaces de solides de révolution avec corps de tiroir cylindrique le passage du fluide se faisant par le corps du tiroir
• B65D 47/00 - Fermetures avec dispositifs pour remplir et vider, ou pour vider
• B65D 47/26 - Fermetures avec dispositifs de décharge autres que des pompes comportant des éléments fonctionnant à la main pour commander l'évacuation avec soupapes coulissantes, p. ex. sous forme de becs d'évacuation coulissants

Abrégé

The device (1) for the sealed connection to a receptacle (2) of an accessory (3), the active proximal part (9) of which is intended to be connected to the inside (4) of the receptacle (2) by an opening (7) in the receptacle (2), includes a first element (15), a second element (16) and a chamber (18), the first element (15) including a proximal end part (32) which is secured by sliding in the proximal direction, with insertion of a lateral sealing component (22), onto a matching part (19) of the receptacle (2), in the proximal direction, the transverse head (14) corresponding to the lower surface of the first element (15) and being provided with a lateral head sealing component (28) and the second element (16) being capable of being pre-assembled with the first element (15) by axial sliding in the proximal direction.

Classes IPC  ?

• B01L 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
• B65D 25/00 - Parties constitutives des autres genres ou types de réceptacles rigides ou semi-rigides
• A61M 39/18 - Procédés ou appareils pour réaliser les connexions sous conditions stériles
• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
• A61J 1/20 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet

Abrégé

A receptacle (1) for biopharmaceutical use includes a flexible container (2) having a wall (4), an internal space (5) for receiving a liquid or pasty biopharmaceutical content, mixing elements (20) adjacent to a given portion (21) of the wall (4), elements (22) for rigid and leaktight connection between the mixing elements (20) and the given portion (21), the mixing elements (20) including a sleeve (24), a suction-delivery opening (26), a suction-delivery part (28), a suction-delivery cavity (29), drive elements (23) for driving in an alternating forward/backward axial sliding sequence, elements (32) for immobilizing the sleeve and the given portion (21), including during the axial sliding movement of the suction-delivery part (28).

Classes IPC  ?

• B01F 11/00 - Mélangeurs avec mécanismes à secousses, oscillants ou vibrants
• B01F 15/00 - Accessoires pour mélangeurs

Abrégé

A pouch (2) includes: a first, inner, envelope (1) which is closed, delimiting a first space (6) forming a pouch stricto sensu (1) intended for receiving a biopharmaceutical product or device; a second, outer, envelope (8) which is closed, delimiting a second space (9) in which is located the first envelope/pouch stricto sensu (1); a spacer element (11); at least one tracer gas located in the first space (6) or in the intermediate space (14) at a partial pressure different from that of the intermediate space or of the first space; and at least one colorimetric detection layer (12), responding to the concentration of tracer gas which reaches it by changing from a first color to a second color, and being an integral part of a wall (3, 4) of the first envelope/defined pouch (1) and/or of a wall (13) of the second envelope and/or of the spacer element.

Classes IPC  ?

• G01N 31/22 - Utilisation des réactifs chimiques
• G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur
• B65D 75/38 - Objets ou matériaux enveloppés dans deux enveloppes ou plus, disposées l'une dans l'autre
• B65D 79/02 - Arrangements ou dispositifs pour indiquer un stockage ou un transport incorrects
• B65D 81/20 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu fournissant une ambiance spécifique pour le contenu, p. ex. température supérieure ou inférieure à la température ambiante sous vide ou pression superatmosphérique ou en atmosphère spéciale, p. ex. sous gaz inerte
• A61L 2/26 - Accessoires
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet

Abrégé

A device including: a bag, a tube section having a wall defining a free longitudinal space, and a plastic connector, which are all fused together, the wall including a contact layer made of a material other than PVC, selected from PE, EVA, PP, ETFE, and PVDF, and a functional layer including at least one basic functional layer of a material selected for the function thereof (flexibility, sturdiness, handling, opacity or transparence, gas barrier) and selected from the family including PE, PET, a PA, EVA, EVOH, SEBS, PETG, and PVDF, a bag, another tube section, and/or a connector fused to the biopharmaceutical tube and including a contact layer made of a material capable of being in contact with the biopharmaceutical material, which is capable of being fused onto itself, and which is identical or similar to the material of the contact layer of the biopharmaceutical tube.

Classes IPC  ?

• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• A61J 1/20 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue
• B32B 27/30 - Produits stratifiés composés essentiellement de résine synthétique comprenant une résine vinyliqueProduits stratifiés composés essentiellement de résine synthétique comprenant une résine acrylique
• B32B 27/32 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyoléfines
• B32B 27/08 - Produits stratifiés composés essentiellement de résine synthétique comme seul composant ou composant principal d'une couche adjacente à une autre couche d'une substance spécifique d'une résine synthétique d'une sorte différente
• B32B 27/34 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyamides
• B32B 27/36 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyesters
• B32B 1/08 - Produits tubulaires
• A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
• F16L 11/04 - Manches, c.-à-d. tuyaux flexibles en caoutchouc ou en matériaux plastiques flexibles

Abrégé

a).

Classes IPC  ?

• G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• C12M 1/02 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'agitationAppareillage pour l'enzymologie ou la microbiologie avec des moyens d'échange de chaleur
• C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies

Abrégé

A sterilizable biopharmaceutical packaging includes an opening for inserting biopharmaceutical contents to be sterilized, the opening being separate from a sterilization gas conveyance channel so that the opening can be closed independently and before closing the sterilization gas conveyance channel. The opening is directly adjacent to an inner space for receiving the biopharmaceutical contents so that the contents to be sterilized are inserted directly into the inner space from outside the packaging. The elements for controlling the distribution of the sterilization gas open/close the sterilization gas conveyance channel independently of the opening or closing of the insertion opening. After sterilization, the outer wall, the sterilization gas conveyance channel, and the opening/closing element are capable of remaining rigidly connected therebetween so as to form a sterilized biopharmaceutical packaging that contains the sterilized biopharmaceutical contents and can be subjected to one or more integrity tests at any desired time after the sterilization.

Classes IPC  ?

• B65B 55/18 - Stérilisation du contenu avant ou durant l'emballage par des liquides ou des gaz
• A61L 2/20 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances gazeuses, p. ex. des vapeurs
• B65D 81/24 - Adaptations pour empêcher la détérioration ou l'altération du contenuApplications au réceptacle ou au matériau d'emballage d'agents de conservation des aliments, de fongicides, d'insecticides ou de produits repoussant les animaux
• B65B 55/02 - Stérilisation, p. ex. de paquets finis
• A61L 2/00 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet
• A61L 2/26 - Accessoires

Abrégé

b) thereof, until transversely widened so as to be capable of being unthreaded from both collars (14, 24) and thus be converted to the disassembled state.

Classes IPC  ?

• F16L 27/107 - Raccords réglablesRaccords permettant un déplacement des parties raccordées comportant uniquement une connexion flexible les extrémités des tuyaux étant assemblées au moyen d'un manchon flexible
• F16L 33/30 - Dispositions d'assemblage des manches avec des organes rigidesRaccords rigides pour manches, p. ex. éléments unitaires s'engageant à la fois dans deux manches comprenant uniquement des pièces disposées à l'intérieur des manches
• F16L 37/04 - Accouplements du type à action rapide dans lesquels l'assemblage est maintenu uniquement par friction des parties assemblées avec partie extérieure élastique pressée contre une partie intérieure de fait de son élasticité
• F16L 19/00 - Raccords dans lesquels les surfaces d'étanchéité sont maintenues en contact par un organe, p. ex. un écrou à oreilles vissé dans, ou vissé sur une des parties du raccord
• A61M 39/10 - Raccords ou accouplements pour tubes

Abrégé

A method for the sterile filling of at least one final basic container, includes: providing at least one sterile chamber having at least one sterile entrance port and providing a source container containing the content, located outside the chamber; providing a communication element, a dispensing element and at least one filling member, to form when all are assembled, a sterile fluid filling and transfer line; inserting at least one final container into the chamber; structurally combining at least one final container with at least one filling member; providing inner members and elements in sterile condition for a single-use; inserting the inner element and members which were previously outside the chamber in the chamber in a sterile manner, such that after filling, a new filling process can be performed without sterilizing the inside of the chamber; transferring in a filling step content from the source container into the final container.

Classes IPC  ?

• B65B 3/00 - Emballage de matériaux plastiques, de semi-liquides, de liquides ou de liquides et solides mélangés, dans des réceptacles ou récipients individuels, p. ex. dans des sacs ou sachets, boîtes, cartons, bidons ou pots
• B65B 31/02 - Remplissage, fermeture, ou remplissage et fermeture, de réceptacles dans des chambres maintenues en dépression ou en surpression ou contenant une atmosphère spéciale, p. ex. du gaz inerte

Produits et services

Plastic pouches for pharmaceutical, medical or biological liquids except apparatus, pouches and accessories intended for blood and plasma transfusions such as filters and adsorbents and except therapy apparatus for blood and plasma such as gas exchangers for extra-corporeal therapy application. Disposable sterilization pouches except pouches intended for blood and plasma transfusions.

Produits et services

Plastic medical pouches, sold empty, designed to hold pharmaceutical, medical and biological liquids, and not including apparatus; pouches and accessories intended for blood and plasma transfusions such as filters and adsorbents, and not including therapy apparatus for blood and plasma such as gas exchangers for extra-corporeal therapy application Disposable sterilization pouches, not for medical use, and not including pouches intended for blood and plasma transfusions

Abrégé

A pouch includes: a first closed, inner casing, made of at least one non-porous plastic material with a high-capacity gas barrier, delimiting a first space, forming a pouch stricto sensu for accommodating a biopharmaceutical product or device, a second closed, outer casing, made of at least one non-porous plastic material with a high-capacity gas barrier, delimiting a second space in which the pouch stricto sensu is located, spacer elements, at least one selected tracer gas, located in the first or second space outside of the pouch stricto sensu, with a higher partial pressure than in the second space outside of the pouch stricto sensu or in the first space, at least one colorimetric detector located, respectively, in the second space outside of the pouch stricto sensu or in the first space responsive to the concentration of the tracer gas, by switching from a first color to a second different color.

Classes IPC  ?

• B65D 33/00 - Parties constitutives ou accessoires pour sacs ou sachets
• B65D 79/02 - Arrangements ou dispositifs pour indiquer un stockage ou un transport incorrects
• B65D 77/04 - Objets ou matériaux enfermés dans plusieurs réceptacles disposés les uns dans les autres
• B65D 81/20 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu fournissant une ambiance spécifique pour le contenu, p. ex. température supérieure ou inférieure à la température ambiante sous vide ou pression superatmosphérique ou en atmosphère spéciale, p. ex. sous gaz inerte

Abrégé

The container includes a lower wall and an erect side wall limiting an upper opening of a housing for accommodating a flexible pouch containing a fluid; containment elements including a containment wall, the gap between its peripheral edge and the side wall being limited; the containment wall adapted to be applied against the pouch and held fixed in this position by holding elements arranged in the container and borne by the containment elements by a structural and functional combination, and being movable between an inactive retracted state and an active expanded state, in which a distal end part is either moved away from the side wall or applied there against without any chance of sliding; and adapted to be applied at any desired location of a zone of the side wall such that the containment wall can be applied and held against the pouch regardless of how full the latter is.

Classes IPC  ?

• B65D 25/14 - Garnitures ou revêtements internes
• B65D 35/14 - Réceptacles pliables, de forme tubulaire, conçus de telle sorte que l'expulsion de leur contenu leur donne une déformation permanente, p. ex. tubes souples pour dentifrice ou autres produits plastiques ou semi-liquidesSupports adéquats avec revêtements ou garnitures
• B30B 5/02 - Presses caractérisées par l'emploi d'organes de pression autres que ceux mentionnés dans les groupes et dans lesquels les organes de pression se présentent sous forme d'un élément flexible, mis en action par la pression d'un fluide, p. ex. un diaphragme
• B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
• B65D 85/68 - Réceptacles, éléments d'emballage ou paquets spécialement adaptés à des objets ou à des matériaux particuliers pour machines, moteurs ou véhicules assemblés ou en pièces détachées
• B65D 88/60 - Grands réceptacles caractérisés par des moyens pour faciliter le remplissage ou le vidage par déplacement de parois de parois internes
• B65D 90/04 - Garnitures internes

Abrégé

A first piece mounted in a fixed and rigid manner on a rigid annular collar of a second piece having an end opening, includes a transversal wall; an annular wall forming a skirt, whose inner face includes a part having a larger diameter and a part having a smaller diameter; a holding toric body adjacent to the inner face, deformable between a retracted state and an expanded state, and filled with a swelling medium; and at least one inlet/outlet port for the swelling media, communicating with the holding body. The first piece is dimensioned in relation to the collar, so as to enable the first piece to be slipped onto, or removed from, the second piece, when the holding body is in the retracted state, and to be mounted onto the collar in a fixed, rigid and tight manner, when the holding body is in the expanded state.

Classes IPC  ?

• B65D 53/02 - Colliers ou bagues
• F16J 13/06 - Organes de fermeture amoviblesMoyens de serrage des fermetures fixés uniquement par brides de serrage le long de la circonférence
• B65D 88/54 - Grands réceptacles caractérisés par des moyens pour faciliter le remplissage ou le vidage
• B65D 90/00 - Parties constitutives, détails ou accessoires des grands réceptacles
• B65D 90/04 - Garnitures internes
• F16J 15/46 - Joints d'étanchéité par bague de garniture dilatée ou comprimée dans son logement par pression d'un fluide, p. ex. garnitures gonflables
• B65D 53/00 - Éléments d'étanchéité ou d'emballageÉtanchéité réalisée par matériaux liquides ou plastiques
• B65D 88/26 - Trémies, c.-à-d. réceptacles présentant des sections de déchargement en forme d'entonnoir
• B65D 88/68 - Grands réceptacles caractérisés par des moyens pour faciliter le remplissage ou le vidage en empêchant la formation de ponts par des dispositifs en rotation
• B65D 90/56 - Portes ou fermetures agissant par déformation de parois flexibles

Abrégé

A mounting assembly is provided including a first piece mounted in a fixed, detachable, and sealed manner, on a rigid, annular collar of a second piece having an end opening. The first piece includes an annular peripheral wall having an inner face configured to contact an outer face of the collar. The first piece includes a transverse wall that can enter the opening, and an annular wall forming a skirt, the inner face of the skirt including a larger diameter part, a smaller diameter part, and an intermediate part configured to contact with conjugated parts of the outer face by clamping. The transverse wall and the skirt form one component and are made of a highly flexible material enabling the first piece to be brought into an intermediate state in which the first piece is enlarged to be removed from the second piece, while retaining elastic deformation.

Classes IPC  ?

• B65D 43/02 - Couvercles ou chapeaux amovibles
• B65D 41/16 - Capuchons à enclenchement

Abrégé

Process for closing and cutting into sections a flexible tube, with a cutting element and a pinching closing device for cutting into sections with two cross-sections, each with two parts with indentations that can be placed in removable extension by combination elements and that make a passage with an access, whereby the pinching closing device is in the open or closed state where the cross-sections are closed by locking members and where the surfaces form a pinching closing passage of the tube; the pinching region of the tube is positioned in the indentation of a cross-section; the other cross-section is brought opposite the preceding one and the pinching closing device in the closed state, with cooperation of the locking elements, the tube being positively pinched and closed in two positive pinching zones, and thus held in place; the tube is cut into sections between the parts in the closed state, using the cutting element by passing it into the passage without it interfering with the pinching closing device; and the parts are dissociated.

Classes IPC  ?

• A61B 17/46 - Embryotomes
• F16K 7/04 - Dispositifs d'obturation à diaphragme, p. ex. dont un élément est déformé, sans être déplacé entièrement, pour fermer l'ouverture à diaphragme tubulaire dont l'étranglement est assuré par une force extérieure radiale
• B26B 3/00 - Couteaux à main à lame fixe
• A61M 39/28 - Moyens de serrage pour l'écrasement des tubes flexibles, p. ex. brides de serrage à rouleaux
• A61B 17/122 - Clamps ou pinces, p. ex. pour le cordon ombilical

Abrégé

A mixing container includes a flexible container, mixing elements and an upper bearing having a rigid flange. The flange is provided with an insertion passage that fluidically communicates with the inside space on one end and with the outside of the container on the other end. The flange is fixed in a rigid and sealing manner to the upper part of the wall of the container around an insertion opening, the insertion passage and the insertion opening communicating fluidically. The flange also supports, on the inside thereof, an upper bearing that is arranged inside, adjacent to the insertion passage, without preventing the fluidic communication between the insertion passage and the insertion opening. The mixing container is used to receive a biopharmaceutical content to be mixed.

Classes IPC  ?

• C12M 1/06 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'introduction de gaz avec agitateur, p. ex. avec agitateur à turbine
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus

Abrégé

The pinching device includes two cross-sections, each having a hollow part with a male indentation and a female indentation, and locking elements, whereby the surfaces of the indentations form a positive pinching passage of the tube; the male indentation has a U shape with a core and two wings; the female indentation has a U shape with a core and two wings; and the pinching passage has a U shape with a core and two wings; the two opposite wings will draw together toward their ends that are opposite to the cores of the indentations, and each of the two wings of the pinching passage has an opening whose width will diminish towards its end that is opposite to the core of the pinching passage; the width of the opening of the pinching passage is at most slightly smaller than twice the thickness of the wall of the flexible tube to be pinched, and, designed to constitute a pinching closing device, it is disposable, performing a function of closing the tube on itself in the pinching region, preventing any passage of fluid into the tube.

Classes IPC  ?

• B23P 11/00 - Assemblage ou désassemblage de pièces ou d'objets métalliques par des processus du travail du métal non prévus ailleurs
• B21D 39/00 - Utilisation de procédés permettant d'assembler des objets ou des parties d'objets, p. ex. revêtement par des tôles, autrement que par placageDispositifs de mandrinage des tubes
• B23P 19/00 - Machines effectuant simplement l'assemblage ou la séparation de pièces ou d'objets métalliques entre eux ou des pièces métalliques avec des pièces non métalliques, que cela entraîne ou non une certaine déformationOutils ou dispositifs à cet effet dans la mesure où ils ne sont pas prévus dans d'autres classes
• F16K 7/04 - Dispositifs d'obturation à diaphragme, p. ex. dont un élément est déformé, sans être déplacé entièrement, pour fermer l'ouverture à diaphragme tubulaire dont l'étranglement est assuré par une force extérieure radiale
• A61M 39/28 - Moyens de serrage pour l'écrasement des tubes flexibles, p. ex. brides de serrage à rouleaux
• A61M 39/14 - Raccords ou accouplements pour tubes pour connecter des tubes ayant des extrémités obturées

Abrégé

A mixing process, a spraying and dispersing device, and a mixing device for implementing the process. In the process, components are introduced into a container equipped with introduction elements and mixing elements and the contents are mixed. A mixing facilitator is provided, a spraying and dispersing device that can be connected to the container at one of its introduction element is provided, able to be in an active functional state in which it makes it possible to spray and to disperse a liquid in the container, and then, in a first phase, the base of the contents and then the components to be mixed are introduced into the container, without filling the latter, and in a second phase, the mixing facilitator is introduced into the container via an introduction element, and it is sprayed and dispersed to the components to be mixed by the spraying and dispersing device that is put into the active functional state.

Classes IPC  ?

• B01F 3/12 - Mélange, p.ex. dispersion, émulsion, selon les phases à mélanger de liquides avec des solides
• B01F 5/20 - Mélangeurs à pulvérisation à ajutages
• B01F 7/16 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins avec agitateurs tournant autour d'un axe vertical
• B01F 15/00 - Accessoires pour mélangeurs

Abrégé

A frame delimits an inside space and includes a peripherally closed side wall and two transverse openings or one transverse opening and a transverse end wall. It is capable of allowing the airtight engagement of the open free edge of a side wall in film form of a receptacle that is at least partially deformable. It is specially designed for the creation of a 3D container. The frame is also able to act as a support for at least one functional port or attachment port of a functional element. Its axial size is adequate for delimiting a space of a size that is at least equal to the axial dimension of the functional element, so that the latter can be completely housed within the inside space.

Classes IPC  ?

• B01F 7/00 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins
• B65D 30/20 - Sacs, sachets ou réceptacles analogues caractérisés par leur forme ou leur conception comportant des plis, p. ex. pour faciliter le repliage
• B65D 88/16 - Grands réceptacles souples
• B01F 7/16 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins avec agitateurs tournant autour d'un axe vertical
• B01F 15/00 - Accessoires pour mélangeurs
• B65D 37/00 - Réceptacles flexibles transportables non prévus ailleurs
• B65D 88/68 - Grands réceptacles caractérisés par des moyens pour faciliter le remplissage ou le vidage en empêchant la formation de ponts par des dispositifs en rotation
• B65D 90/20 - Cadres ou filets, p. ex. pour réceptacles souples

Abrégé

b) is inserted between the two small walls of each gusset in order to prevent these walls from resting on one another. The port is connected to the gas source and the pressure measuring elements. The gas is sent under pressure into the bag, the expansion of the bag being limited by the restraining plates; then, the pressure drop in the bag is compared to a predefined threshold.

Classes IPC  ?

• G01M 3/04 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite

Abrégé

A device for connecting to a vessel an accessory has an active portion that includes a first, second and third member and a chamber. The first member ensures rigid attachment of the device to the vessel, defines a passageway, acts as a holder for the second member and as a translation guide between a first distal state and a second proximal state, contributes as a guide for the third member and participates in defining the chamber. The second member acts as a holder for the third member rigidly attached thereon, defines a mobile member capable of sliding between the first distal state and the second proximal state. The third member includes a head, and acts as a holder for the accessory rigidly attached thereon, defines a mobile member capable of sliding between the first distal state and the second proximal state, ensures in the first distal state the tight closing of the opening using the head, ensures in the second proximal state a protection of the active proximal portion using the head, and participates in defining the chamber.

Classes IPC  ?

• G01D 11/24 - Boîtiers
• G01L 19/14 - Boîtiers

Abrégé

A vessel includes: a pocket capable of assuming a folded state and an expanded state, processing element including an active inner portion; protection element including a side wall, a lower portion and an upper portion defining an inner space, the lower portion being attached to the upper portion of the pocket, the active inner portion being provided in the inner space when the pocket is in the folded state, the peripheral portion of the inner space about the processing element defining a protection chamber; at least one insertion and/or draining opening. The active inner portion is provided inside the pocket adjacent to the lower end portion thereof, the processing element and the protection element are independent in terms of their movements, and the height of the protection chamber is variable and automatically adapts itself based on respectively, the flat-folded, unfolded and expanded states or any intermediate state of the pocket.

Classes IPC  ?

• B01F 7/16 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins avec agitateurs tournant autour d'un axe vertical
• B65D 30/20 - Sacs, sachets ou réceptacles analogues caractérisés par leur forme ou leur conception comportant des plis, p. ex. pour faciliter le repliage

Abrégé

A closed single-use system for mixing, storing and homogenizing liquids, comprising an assembly constituted by a rigid container (1) fitted with a non-invasive pump (4), the container (1) enclosing a generally parallelepipedic single-use bag (2), the lower face and the upper face of which are connected in fixed manner by means of a mixing duct (3) which is inserted into the pump (4) and which, during operation, allows the closed-circuit circulation of the liquid in said bag (2), for example from the bottom of the bag to its top, the pump (4) being open so that the mixing duct (3) can be inserted into it and removed from it.

Classes IPC  ?

• B01F 15/02 - Mécanismes d'alimentation ou d'évacuation

Produits et services

Soft plastic pouches for biological, medical or pharmaceutical liquids.

Produits et services

Soft plastic bags for biological, medical or pharmaceutical liquids.