Abrégé

A sustained release component of a drug delivery device (102) for releasing a drug from a reservoir (104) over a period of time includes an inlet (106) for fluid interconnection with the reservoir and a flow regulating arrangement (100) defining at least part of a flow path from the inlet to at least one outlet (108). The flow regulating arrangement includes a quantity of biodegradable material (110) deployed within and/or adjacent to the flow path so that decomposition of the biodegradable material results in expansion of fluid flow passageways that were initially restricted by the biodegradable material and/or opening of fluid flow passageways that were initially blocked by the biodegradable material.

Classes IPC  ?

• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
• A61M 5/14 - Dispositifs de perfusion, p. ex. perfusion par gravitéPerfusion sanguineAccessoires à cet effet
• A61M 5/148 - Perfusion sous pression, p. ex. utilisant des pompes utilisant des réservoirs sous pression, p. ex. au moyen de pistons flexibles
• A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main

Abrégé

A drug delivery device is formed from an elastic sleeve deployed around a core, with first and second edge portions inwardly inverted. When a fluid is introduced between the core and the sleeve, the sleeve inflates to form a reservoir with a pressure of the fluid pressing the inwardly-inverted extremities portions against the core. The device is preferably anchored by providing a stem of conformable material which is depressed by pressure applied by adjacent edges of a layer of tissue to achieve tissue-wedged anchoring of the device.

Classes IPC  ?

• A61M 5/148 - Perfusion sous pression, p. ex. utilisant des pompes utilisant des réservoirs sous pression, p. ex. au moyen de pistons flexibles
• A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
• A61M 5/152 - Perfusion sous pression, p. ex. utilisant des pompes utilisant des réservoirs sous pression, p. ex. au moyen de pistons flexibles mis sous pression par contraction de réservoirs élastiques
• A61M 5/142 - Perfusion sous pression, p. ex. utilisant des pompes
• A61M 25/10 - Cathéters à ballon

Abrégé

A drug delivery device is formed from an elastic sleeve deployed around a core, with first and second edge portions inwardly inverted. When a fluid is introduced between the core and the sleeve, the sleeve inflates to form a reservoir with a pressure of the fluid pressing the inwardly-inverted extremities portions against the core. The device is preferably anchored by providing a stem of conformable material which is depressed by pressure applied by adjacent edges of a layer of tissue to achieve tissue-wedged anchoring of the device.

Classes IPC  ?

• A61M 5/152 - Perfusion sous pression, p. ex. utilisant des pompes utilisant des réservoirs sous pression, p. ex. au moyen de pistons flexibles mis sous pression par contraction de réservoirs élastiques

Abrégé

a), and is preferably filled with a liquid drug after deployment via a filling needle (24, 222) extending within the channel of the hollow needle (12, 212).

Classes IPC  ?

• A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
• A61M 5/32 - AiguillesParties constitutives des aiguilles relatives au raccordement de celles-ci à la seringue ou au manchonAccessoires pour introduire l'aiguille dans le corps ou l'y maintenirDispositifs pour la protection des aiguilles
• A61M 5/142 - Perfusion sous pression, p. ex. utilisant des pompes

Abrégé

A system (10, 200) and corresponding method for introducing a drug delivery device (18, 218) through at least part of a biological barrier starts with the drug delivery device (18, 218) deployed within a channel of a hollow needle (12, 212). The hollow needle is inserted into the biological barrier and the drug delivery device is pushed forward by a suitable plunger. The drug delivery device is preferably anchored to the biological barrier through a radially expanding retention arrangement (36, 36', 36a), and is preferably filled with a liquid drug after deployment via a filling needle (24, 222) extending within the channel of the hollow needle (12, 212).

Classes IPC  ?

• A61M 5/14 - Dispositifs de perfusion, p. ex. perfusion par gravitéPerfusion sanguineAccessoires à cet effet

Abrégé

A drug delivery device includes a first portion, formed primarily from elastomeric material, and a closure portion, cooperating with an opening of the first portion so as to complete an inflatable drug reservoir. The closure portion extends into the first portion inwards from the opening, defining at least one region of overlap between the first portion and the closure portion. The first portion and the closure portion define an outlet flow path for releasing a drug from the drug reservoir, with at least part of the outlet flow path passing between the first portion and the closure portion in the region of overlap. The region of overlap is disposed so as to be acted upon by a pressure within the drug reservoir thereby changing a flow impedance of the outlet flow path to provide an at least partially pressure compensated flow regulating mechanism.

Classes IPC  ?

• A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps
• A61M 5/142 - Perfusion sous pression, p. ex. utilisant des pompes
• A61M 5/148 - Perfusion sous pression, p. ex. utilisant des pompes utilisant des réservoirs sous pression, p. ex. au moyen de pistons flexibles

Abrégé

A drug delivery device includes a first portion, formed primarily from elastomeric material, and a closure portion, cooperating with an opening of the first portion so as to complete an inflatable drug reservoir. The closure portion extends into the first portion inwards from the opening, defining at least one region of overlap between the first portion and the closure portion. The first portion and the closure portion define an outlet flow path for releasing a drug from the drug reservoir, with at least part of the outlet flow path passing between the first portion and the closure portion in the region of overlap. The region of overlap is disposed so as to be acted upon by a pressure within the drug reservoir thereby changing a flow impedance of the outlet flow path to provide an at least partially pressure compensated flow regulating mechanism.

Classes IPC  ?

• A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
• A61K 9/22 - Pilules, pastilles ou comprimés du type à libération prolongée ou discontinue

Abrégé

A drug delivery device is formed from an elastomeric element, including an inflatable drug reservoir and a flexible sleeve, and an insert inserted within the flexible sleeve. The insert cooperates with the flexible sleeve to form an at least partially pressure compensated flow regulating mechanism.

Classes IPC  ?

• A61M 37/00 - Autres appareils pour introduire des agents dans le corpsPercutanisation, c.-à-d. introduction de médicaments dans le corps par diffusion à travers la peau