Abrégé

A system and method for the measurement of radiation emitted from the body, for example, is presented. In one example, radiation sensors (e.g., gamma radiation sensors) may be used to measure activity proximate an injection site as a function of time. In some embodiments, one or more rangefinders may be employed to determine a size and/or position of a subject relative to the radiation sensors to better account for varying material densities within the system in estimating, for example, the amount of radioactive material in the tissue proximate the injection site. With an estimated function of radioactive material proximate the injection site as a function of time known, an estimated arterial input function may be determined, allowing for calculation of a correction factor that may be applied by a clinician during nuclear medical imaging. The magnitude, location, and volume of the radioactive source in the body may also be estimated.

Classes IPC  ?

• A61B 6/03 - Tomographie informatisée
• G01C 3/02 - Mesure des distances dans la ligne de viséeTélémètres optiques Détails
• G01S 15/10 - Systèmes pour mesurer la distance uniquement utilisant la transmission de trains discontinus d'ondes modulées par impulsions
• G01S 17/10 - Systèmes déterminant les données relatives à la position d'une cible pour mesurer la distance uniquement utilisant la transmission d'ondes à modulation d'impulsion interrompues
• G01T 1/02 - Dosimètres

Abrégé

A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte, and provide real time feedback to an autoinjector or other administration device or person. The feedback may include identification of an infiltration event and/or a likelihood that an infiltration event resulted in a radiation dose to a patient above a certain value, among other things.

Classes IPC  ?

• G01T 1/161 - Applications au domaine de la médecine nucléaire, p. ex. comptage in vivo
• A61B 6/42 - Agencements pour détecter des radiations spécialement adaptés au diagnostic par radiations
• A61B 6/46 - Agencements pour l’interface avec l’opérateur ou avec le patient
• G01T 1/164 - Scintigraphie

Abrégé

A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte is presented. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte. In some cases, the system utilizes computer program code executable by a computer processor that performs the steps of receiving signal data, accessing reference data, and comparing the signal data to the reference data to determine a likelihood of improper administration of the radioactive analyte to the subject.

Classes IPC  ?

• G01T 1/161 - Applications au domaine de la médecine nucléaire, p. ex. comptage in vivo
• A61B 6/42 - Agencements pour détecter des radiations spécialement adaptés au diagnostic par radiations
• A61B 6/46 - Agencements pour l’interface avec l’opérateur ou avec le patient
• G01T 1/164 - Scintigraphie

Abrégé

Various embodiments of a device for in-vivo measurements radiopharmaceuticals used for diagnosis and monitoring of radiotherapy are presented. In some embodiments, the present disclosure relates to a device having a cannula that may include a measurement chamber, a radiation detector and a delivery lumen, wherein the device may be used to both deliver material to the patient (e.g., radiotracers used in radiopharmaceuticals) and measure levels and concentrations of radioactive material in, for example, the patient's blood both during and after administration of the radioactive material. In some embodiments, a plunger may be utilized to draw blood through a first opening into the measurement chamber and then return it to the bloodstream. In some embodiments, particle absorbing materials may be used to limit measurements to materials within the measurement chamber or other area of interest.

Classes IPC  ?

• A61B 6/40 - Agencements pour générer des radiations spécialement adaptés au diagnostic par radiations
• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• A61B 6/42 - Agencements pour détecter des radiations spécialement adaptés au diagnostic par radiations
• A61B 6/50 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des parties du corps spécifiquesAppareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des applications cliniques spécifiques

Abrégé

A system and method for determining accumulated radiation dose is presented. In some embodiments, the system and method include use of one or more RADFETs to measure and accumulated radiation dose over a desired period of time from an area of interest in a patient. In some embodiments, the one or more RADFETs may be arranged on a test strip, and electrical circuitry provided to selectively couple certain terminals of the RADFETS together to facilitate improved measurement of accumulated dose. A reader may also be utilized wherein the reader may receive a test strip, decouple the electrical connections between select terminals, inject a current into the RADFET and/or measure a voltage from the RADFET corresponding to an accumulated radiation dose.

Classes IPC  ?

• G01T 1/02 - Dosimètres
• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
• G01T 1/161 - Applications au domaine de la médecine nucléaire, p. ex. comptage in vivo

Abrégé

A system and method for determining accumulated radiation dose is presented. In some embodiments, the system and method include use of one or more RADFETs to measure and accumulated radiation dose over a desired period of time from an area of interest in a patient. In some embodiments, the one or more RADFETs may be arranged on a test strip, and electrical circuitry provided to selectively couple certain terminals of the RADFETS together to facilitate improved measurement of accumulated dose. A reader may also be utilized wherein the reader may receive a test strip, decouple the electrical connections between select terminals, inject a current into the RADFET and/or measure a voltage from the RADFET corresponding to an accumulated radiation dose.

Classes IPC  ?

• G01T 1/02 - Dosimètres
• G01T 1/164 - Scintigraphie
• A61B 6/03 - Tomographie informatisée
• G01T 1/202 - Mesure de l'intensité de radiation avec des détecteurs à scintillation le détecteur étant du cristal
• G01T 3/06 - Mesure de flux de neutrons avec des détecteurs à scintillation

Abrégé

Various embodiments of a device for in-vivo measurements radiopharmaceuticals used for diagnosis and monitoring of radiotherapy are presented. In some embodiments, the present disclosure relates to a device having a cannula that may include a measurement chamber, a radiation detector and a delivery lumen, wherein the device may be used to both deliver material to the patient (e.g., radiotracers used in radiopharmaceuticals) and measure levels and concentrations of radioactive material in, for example, the patient's blood both during and after administration of the radioactive material. In some embodiments, particles emitted by the radioactive material interact with a scintillation material, resulting in the release of light that may be transmitted, via the scintillation material and/or fiber optic material, to an optical detectors or processor for processing. In some embodiments, particle absorbing materials may be used to limit measurements to materials within the measurement chamber or other area of interest.

Classes IPC  ?

• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• A61B 6/40 - Agencements pour générer des radiations spécialement adaptés au diagnostic par radiations
• A61B 6/42 - Agencements pour détecter des radiations spécialement adaptés au diagnostic par radiations
• A61B 6/50 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des parties du corps spécifiquesAppareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des applications cliniques spécifiques

Abrégé

A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte, and identify patient administration factors that correlate with improper administration over a set of patients so as to identify administration risk factors to improve administration of radioactive analyte. In some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Classes IPC  ?

• G01T 1/161 - Applications au domaine de la médecine nucléaire, p. ex. comptage in vivo
• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• G01T 1/164 - Scintigraphie

Abrégé

A system and method for the measurement of radiation emitted from the body, for example, is presented. In one example, radiation sensors (e.g., gamma radiation sensors) may be used to measure activity proximate an injection site as a function of time. In some embodiments, one or more rangefinders may be employed to determine a size and/or position of a subject relative to the radiation sensors to better account for varying material densities within the system in estimating, for example, the amount of radioactive material in the tissue proximate the injection site. With an estimated function of radioactive material proximate the injection site as a function of time known, an estimated arterial input function may be determined, allowing for calculation of a correction factor that may be applied by a clinician during nuclear medical imaging. The magnitude, location, and volume of the radioactive source in the body may also be estimated.

Classes IPC  ?

• A61B 6/03 - Tomographie informatisée
• G01S 15/10 - Systèmes pour mesurer la distance uniquement utilisant la transmission de trains discontinus d'ondes modulées par impulsions
• G01C 3/02 - Mesure des distances dans la ligne de viséeTélémètres optiques Détails
• G01T 1/02 - Dosimètres
• G01S 17/10 - Systèmes déterminant les données relatives à la position d'une cible pour mesurer la distance uniquement utilisant la transmission d'ondes à modulation d'impulsion interrompues

Abrégé

A system and method for the measurement of radiation emitted from the body, for example, is presented. In one example, radiation sensors (e.g., gamma radiation sensors) may be used to measure activity proximate an injection site as a function of time. With that data, a function describing an amount of radioactive material in tissue proximate the injection site as a function of time may be estimated where an amount of radioactive material in the tissue at a time t is known. When an array of sensors is employed, the amount of radioactive material in the tissue proximate the injection site may be determined directly by the system. With an estimated function of radioactive material proximate the injection site as a function of time known, an estimated arterial input function may be determined, allowing for calculation of a correction factor that may be applied by a clinician during nuclear medical imaging.

Classes IPC  ?

• A61B 6/40 - Agencements pour générer des radiations spécialement adaptés au diagnostic par radiations
• A61B 6/42 - Agencements pour détecter des radiations spécialement adaptés au diagnostic par radiations
• G01T 1/164 - Scintigraphie

Abrégé

e.g. t t is known. When an array of sensors is employed, the amount of radioactive material in the tissue proximate the injection site may be determined directly by the system. With an estimated function of radioactive material proximate the injection site as a function of time known, an estimated arterial input function may be determined, allowing for calculation of a correction factor that may be applied by a clinician during nuclear medical imaging.

Classes IPC  ?

• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• G01T 1/161 - Applications au domaine de la médecine nucléaire, p. ex. comptage in vivo

Produits et services

Medical device, namely, a radiation detector and recorded software, sold together, for assessing medical treatment of tumors Technical consultation and support services, namely, providing analyzed medical information to medical professionals that is the result of medical information which has been gathered by and transmitted via medical devices in remote locations and then processed

Abrégé

A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte. In some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Classes IPC  ?

• G01T 1/161 - Applications au domaine de la médecine nucléaire, p. ex. comptage in vivo
• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• G01T 1/164 - Scintigraphie

Produits et services

Software as a service (SAAS) services featuring software for use in calculating, evaluating, storing, and presenting to a user data measured by a medical device

Produits et services

Medical device, namely, a radiation detector and software, sold together, for dynamically measuring radiotracer in blood and tissue

Abrégé

A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Classes IPC  ?

• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• G01T 1/161 - Applications au domaine de la médecine nucléaire, p. ex. comptage in vivo
• G01T 1/164 - Scintigraphie

Abrégé

A system for the measurement of radiation emitted from an in-vivo administered radioactive analyte. The system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Classes IPC  ?

• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations

Produits et services

Medical device, namely, a radiation detector and software, sold together, for assessing medical treatment of tumors Research in the field of medical devices and software for medical devices; product design and development in the field of medical devices and software for medical devices; software development in the field of medical devices Technical consultation and support services, namely, providing analyzed medical information to medical professionals that is the result of medical information which has been gathered by and transmitted via medical devices in remote locations and then processed

Abrégé

A system and method for determining accumulated radiation dose is presented. In some embodiments, the system and method include use of one or more RADFETs to measure and accumulated radiation dose over a desired period of time from an area of interest in a patient. In some embodiments, the one or more RADFETs may be arranged on a test strip, and electrical circuitry provided to selectively couple certain terminals of the RADFETS together to facilitate improved measurement of accumulated dose. A reader may also be utilized wherein the reader may receive a test strip, decouple the electrical connections between select terminals, inject a current into the RADFET and/or measure a voltage from the RADFET corresponding to an accumulated radiation dose.

Classes IPC  ?

• A61B 6/03 - Tomographie informatisée
• G01T 1/02 - Dosimètres
• G01T 1/164 - Scintigraphie
• G01T 1/202 - Mesure de l'intensité de radiation avec des détecteurs à scintillation le détecteur étant du cristal
• G01T 3/06 - Mesure de flux de neutrons avec des détecteurs à scintillation

Abrégé

A system for the measurement of radiation emitted from an in-vivo administered radioactive analyte. The system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.

Classes IPC  ?

• G01T 1/164 - Scintigraphie
• G01T 1/20 - Mesure de l'intensité de radiation avec des détecteurs à scintillation
• G01T 1/202 - Mesure de l'intensité de radiation avec des détecteurs à scintillation le détecteur étant du cristal
• G01T 1/203 - Mesure de l'intensité de radiation avec des détecteurs à scintillation le détecteur étant fait de matières plastiques
• G01T 1/208 - Circuits spécialement adaptés aux détecteurs à scintillation, p. ex. à l'élément photomultiplicateur
• G01T 7/00 - Détails des instruments de mesure des radiations