The main problem addressed by the present invention is the problem of providing a crystalline silicon nitride powder that makes it possible to obtain a silicon nitride sintered body having easy sinterability, sufficient mechanical strength characteristics, and excellent thermal conductivity. The present invention provides a silicon nitride powder characterized in that the mass content of various metal impurities (Fe, Ti, Cr, Ni, Al, Ca, Mg, Na, and K) is controlled within a suitable range and the silicon nitride powder has powder characteristics suitable for obtaining a silicon nitride sintered body having both excellent mechanical characteristics and high thermal conductivity. Also provided are: a silicon nitride sintered body having both sufficient mechanical strength characteristics and excellent thermal conductivity as a result of molding and sintering a sintering raw material containing the silicon nitride powder and a sintering aid; and a method for producing the silicon nitride sintered body.
A method for producing a 2-(halogenated methyl)naphthalene represented by general formula (1):
A method for producing a 2-(halogenated methyl)naphthalene represented by general formula (1):
where X is a halogen atom. The method includes a halogenation process of reacting 2-methylnaphthalene with a halogenating agent under light irradiation, in an aliphatic hydrocarbon solvent.
C07C 255/33 - Nitriles d'acides carboxyliques ayant des groupes cyano liés à des atomes de carbone acycliques ayant des groupes cyano liés à des atomes de carbone acycliques d'un squelette carboné contenant au moins un cycle aromatique à six chaînons avec des groupes cyano reliés au cycle aromatique à six chaînons ou au système cyclique condensé contenant ce cycle, par l'intermédiaire de chaînes carbonées saturées
C07C 22/04 - Composés cycliques contenant des atomes d'halogène liés à un atome de carbone acyclique ayant une insaturation dans les cycles contenant des cycles aromatiques à six chaînons
The present invention addresses the problem of providing: a blood-brain barrier model that can be produced in a relatively simple manner and in which a physiological barrier function and selective permeability are reproduced; and a method for producing the blood-brain barrier model. A blood-brain barrier model in which a physiological barrier function and selective permeability are reproduced can be produced in a relatively simple manner in a blood-brain barrier model having three cell layers of perisites, astrocytes, and vascular endothelial cells by culturing vascular endothelial cells so as to form a sheet structure on the surface of a porous membrane and so that perisites are present in an internal structure layer of the porous membrane.
Provided is a carrier for cell culture, characterized in that the carrier comprises: two or more porous polymer membranes; a spacer member provided between the two or more porous polymer membranes and having one or more openings; and two protective members each having one or more openings and holding the two or more porous polymer membranes therebetween; and in that edges of the porous polymer membranes and an edge of the spacer member are melt-bonded and fixed, edges of the porous polymer membranes and edges of the protective members are melt-bonded and fixed by a seal member, and a space having an average thickness of 10 μm-1,500 μm is formed between two or more adjacent porous polymer membranes.
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
C12M 3/04 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus comportant des moyens fournissant des couches minces
C12N 11/08 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique le support étant un polymère synthétique
A cell culture device according to the present disclosure comprises: a culture chamber for culturing suspension cells; a flow path having a culture medium supply port and a culture medium discharge port, and provided adjacent to part or all of the outer side of at least one surface of the culture chamber; an oxygen permeable membrane provided to at least part of the flow path and/or the culture chamber; and a cell seeding port provided to at least part of the culture chamber.
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 1/10 - Appareillage pour l'enzymologie ou la microbiologie montés rotativement
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
C12N 1/00 - Micro-organismes, p. ex. protozoairesCompositions les contenantProcédés de culture ou de conservation de micro-organismes, ou de compositions les contenantProcédés de préparation ou d'isolement d'une composition contenant un micro-organismeLeurs milieux de culture
C12N 5/12 - Cellules fusionnées, p. ex. hybridomes
The present disclosure provides a cell culture device comprising: a culture chamber for culturing suspension cells; a first flow path adjacent to the culture chamber, and having a first culture medium supply port and a first culture medium discharge port; a second flow path having a second culture medium supply port and a second culture medium discharge port; a semi-permeable membrane disposed in at least a portion between the first flow path and the second flow path; and a seeding port provided to at least a portion of the culture chamber.
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
C12N 1/00 - Micro-organismes, p. ex. protozoairesCompositions les contenantProcédés de culture ou de conservation de micro-organismes, ou de compositions les contenantProcédés de préparation ou d'isolement d'une composition contenant un micro-organismeLeurs milieux de culture
C12N 5/12 - Cellules fusionnées, p. ex. hybridomes
8.
L-GLUTAMATE OXIDASE, AND METHOD FOR PRODUCING α-KETOGLUTARIC ACID OR HYDROXYPIPECOLIC ACID
The present invention addresses the problem of providing a glutamate oxidase that efficiently converts glutamic acid to α-ketoglutaric acid. The present invention provides the following novel glutamate oxidase. A glutamate oxidase having a polypeptide, the glutamate oxidase including any of the following amino acid sequences (1), (2), and (3): (1) An amino acid sequence represented by SEQ ID NO: 2 or 4; (2) an amino acid sequence having one or more amino acid substitutions, deletions, and/or additions in an amino acid sequence represented by SEQ ID NO: 2 or 4; and (3) an amino acid sequence having 90% or greater sequence identity with an amino acid sequence represented by SEQ ID NO: 2 or 4.
A gas separation membrane unit capable of performing gas separation excellent in recovery rate and purity of a product gas, and a gas separation system using the same. The gas separation membrane unit includes multiple gas separation membrane modules combined in parallel, each of the gas separation membrane modules includes a gas inlet; a non-permeated gas outlet; and a permeated gas outlet, the gas inlet, the non-permeated gas outlet, and the permeated gas outlet are shared to constitute a gas inlet, a non-permeated gas outlet, and a permeated gas outlet of the gas separation membrane unit, and a coefficient of variation of a gas separation selectivity among the plurality of gas separation membrane modules is 0.01 or more and 0.49 or less, or has a coefficient of variation of a gas permeability among the plurality of gas separation membrane modules is 0.01 or more and 0.49 or less.
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
B01D 69/02 - Membranes semi-perméables destinées aux procédés ou aux appareils de séparation, caractérisées par leur forme, leur structure ou leurs propriétésProcédés spécialement adaptés à leur fabrication caractérisées par leurs propriétés
Provided is a polyamide resin composition having suppressed water absorption, good dimensional stability, good tensile strength, and other tensile characteristics sufficient for the utility thereof. The polyamide resin composition according to the present invention comprises: a polyamide resin (A) that contains two or more polyamide resins (A1) having a constituent unit derived from a reactant of pentamethylenediamine and an aliphatic dicarboxylic acid; and a filler (B). The ratio X of the polyamide resin composition as determined by formula (1) in1H-NMR is 4.74-5.98. Formula (1): [(i) + (ii) + (iii)] / (iii) = X (In formula (1) , (i) is the integrated value of a chemical shift of 1.20-1.90 ppm, (ii) is the integrated value of a chemical shift of 2.05-2.50 ppm, and (iii) is the integrated value of a chemical shift of 3.15-3.50 ppm.
Provided is a polyamide resin composition having suppressed water absorption, good productivity, and favorable mechanical properties such as flexural strength and flexural modulus. A polyamide resin composition according to the present invention contains: a polyamide resin (A) containing two or more polyamide resins (A1), each having a constituent unit derived from a reaction product of pentamethylenediamine and an aliphatic dicarboxylic acid; and a resin (B) having a functional group reactive with an amino group and/or a carboxyl group, wherein 2.0 to 7.0 mass% of the resin (B) having a functional group reactive with an amino group and/or a carboxyl group is contained in 100 mass% of the polyamide resin composition, and a ratio X determined by formula (1) is 4.74-5.98 in 1H-NMR of the polyamide resin composition. (The resin (B) having a functional group reactive with an amino group and/or a carboxyl group excludes the polyamide resins (A).) (1) [(i) + (ii) + (iii)]/(iii) = X (In formula (1), (i) is an integrated value of a chemical shift of 1.20 to 1.90 ppm, (ii) is an integrated value of a chemical shift of 2.05 to 2.50 ppm, and (iii) is an integrated value of a chemical shift of 3.15 to 3.50 ppm.)
C08L 77/06 - Polyamides dérivés des polyamines et des acides polycarboxyliques
C08L 23/16 - Copolymères de l’éthylène et du propylène ou de l’éthylène, du propylène et de diène
C08L 33/04 - Homopolymères ou copolymères des esters
C08L 53/02 - Compositions contenant des copolymères séquencés possédant au moins une séquence d'un polymère obtenu par des réactions ne faisant intervenir que des liaisons non saturées carbone-carboneCompositions contenant des dérivés de tels polymères contenant des monomères vinylaromatiques et des diènes conjugués
12.
POLYAMIDE RESIN COMPOSITION CONTAINING POLYAMIDE RESIN, CARBON FIBERS, AND RESIN CARBIDE, AND MOLDED BODY USING SAME
Provided is a polyamide resin composition that contains a polyamide resin, carbon fibers, and a resin carbide. The amount of the polyamide resin is 60 to 90 mass%, and the total of the carbon fiber content and the resin carbide content is 10 to 40 mass%, relative to 100 mass% of the entire composition. The resin carbide is observed as non-fibrous materials which have a long diameter L of 50 μm or less and for which the aspect ratio L/D of the long diameter L to the short diameter D is 5 or less. The average area per non-fibrous material is 5 μm2to 15 μm2. The polyamide resin composition exhibits fluidity and an elastic modulus equivalent or superior to those in a case in which virgin carbon fibers are added.
C08L 77/00 - Compositions contenant des polyamides obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
C08J 5/04 - Renforcement des composés macromoléculaires avec des matériaux fibreux en vrac ou en nappes
Provided is a biodegradable resin composition comprising an aliphatic polyester copolymer (α) and a biodegradable resin (β) (excluding the aliphatic polyester copolymer (α)), wherein the aliphatic polyester copolymer (α) includes a structure (HB) derived from 3-hydroxybutanoic acid and a structure (HA) derived from a 3-hydroxyalkanoic acid (excluding 3-hydroxybutanoic acid), the proportion (HB/HA) of the structure (HB) derived from 3-hydroxybutanoic acid to the structure (HA) derived from a 3-hydroxyalkanoic acid (excluding 3-hydroxybutanoic acid), in the aliphatic polyester copolymer (α), exceeds 95/5 by mole. The biodegradable resin composition has a weight-average molecular weight higher than 70,000 but lower than 310,000.
C08L 67/04 - Polyesters dérivés des acides hydroxycarboxyliques, p. ex. lactones
C08L 101/16 - Compositions contenant des composés macromoléculaires non spécifiés les composés macromoléculaires étant biodégradables
D01F 6/92 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de mélanges de produits de polycondensation comme constituant majeur avec d'autres polymères ou des composés de bas poids moléculaire de polyesters
Provided is a composition able to form a good coating film. Provided is a composition that contains: an aqueous polyurethane dispersion (PUD) containing a polyurethane resin (U) having a structure derived from an acidic group-containing polyol (B), a structure derived from a hydrophobic substituent group-containing ethylene glycol (C), a structure derived from an acidic group-free polyol (A) (excluding the hydrophobic substituent group-containing ethylene glycol (C)) and a structure derived from a polyisocyanate (D); a functional additive (E); and a pigment (F).
C09D 175/08 - Polyuréthanes à partir de polyéthers
B05D 7/24 - Procédés, autres que le flocage, spécialement adaptés pour appliquer des liquides ou d'autres matériaux fluides, à des surfaces particulières, ou pour appliquer des liquides ou d'autres matériaux fluides particuliers pour appliquer des liquides ou d'autres matériaux fluides particuliers
C08G 18/00 - Polymérisats d'isocyanates ou d'isothiocyanates
A hydrolyzable resin and a filler are each efficiently recovered from a composite containing hydrolyzable resin and filler. The present invention is a method for treating a composite that contains a hydrolyzable resin (a1) and a filler, the method comprising: a contact step (1) for bringing the composite into contact with a subcritical fluid to obtain a contact liquid; a treatment step (2) for maintaining the state of contact between the composite and subcritical fluid in the contact liquid for a certain period of time to obtain a treatment liquid containing a hydrolyzable resin (a2) in which a portion or all of the hydrolyzable resin (a1) has undergone decomposition and/or separation; a separation step (3) for separating the hydrolyzable resin (a2) and the filler from the treatment liquid; and a recovery step (4) for individually recovering the separated hydrolyzable resin (a2) and filler.
C08J 11/14 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation par traitement avec de la vapeur ou de l'eau
B29B 17/02 - Séparation de matières plastiques des autres matières
18.
GAS SEPARATION SYSTEM AND METHOD FOR PRODUCING CO2 ENRICHED GAS AND N2 ENRICHED GAS
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
Disclosed is a polyimide precursor composition comprising a polyimide precursor having a repeating unit represented by the following general formula (I) and at least one imidazole compound as an optional component in a predetermined amount. By using this composition, a polyimide film can be produced that has improved light transmittance and adhesion in a polyimide film/substrate laminate, while making use of the advantage of an aromatic polyimide film, such as heat resistance and coefficient of linear thermal expansion.
Disclosed is a polyimide precursor composition comprising a polyimide precursor having a repeating unit represented by the following general formula (I) and at least one imidazole compound as an optional component in a predetermined amount. By using this composition, a polyimide film can be produced that has improved light transmittance and adhesion in a polyimide film/substrate laminate, while making use of the advantage of an aromatic polyimide film, such as heat resistance and coefficient of linear thermal expansion.
Disclosed is a polyimide precursor composition comprising a polyimide precursor having a repeating unit represented by the following general formula (I) and at least one imidazole compound as an optional component in a predetermined amount. By using this composition, a polyimide film can be produced that has improved light transmittance and adhesion in a polyimide film/substrate laminate, while making use of the advantage of an aromatic polyimide film, such as heat resistance and coefficient of linear thermal expansion.
In the formula, X1 contains (i) 50 mol % or more of a structure represented by formula (1-1) and contains 70 mol % or more of a structure represented by formula (1-1) and a structure represented by formula (1-2) in total; or contains (ii) 70 mol % or more of a structure represented by formula (1-1) and/or a structure represented by formula (1-2); and Y1 contains the structure represented by formula (B) in an amount of 70 mol % or more. However, in the case of (ii) above, the polyimide precursor composition contains at least one imidazole compound in an amount of 0.01 mol or more and less than 1 mol per 1 mol of the repeating unit of the polyimide precursor.
Disclosed is a polyimide precursor composition comprising a polyimide precursor having a repeating unit represented by the following general formula (I) and at least one imidazole compound as an optional component in a predetermined amount. By using this composition, a polyimide film can be produced that has improved light transmittance and adhesion in a polyimide film/substrate laminate, while making use of the advantage of an aromatic polyimide film, such as heat resistance and coefficient of linear thermal expansion.
In the formula, X1 contains (i) 50 mol % or more of a structure represented by formula (1-1) and contains 70 mol % or more of a structure represented by formula (1-1) and a structure represented by formula (1-2) in total; or contains (ii) 70 mol % or more of a structure represented by formula (1-1) and/or a structure represented by formula (1-2); and Y1 contains the structure represented by formula (B) in an amount of 70 mol % or more. However, in the case of (ii) above, the polyimide precursor composition contains at least one imidazole compound in an amount of 0.01 mol or more and less than 1 mol per 1 mol of the repeating unit of the polyimide precursor.
C03C 17/32 - Traitement de surface du verre, p. ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement par des matières organiques avec des résines synthétiques ou naturelles
C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides
A hollow fiber element for a separation membrane module, including a plurality of hollow fiber membranes, and a tube sheet which is formed of a cured product of an epoxy composition and fixes and adheres at least one of the ends of the hollow fiber membranes. The cured product has a breaking strength retention of 75% or higher as measured in the form of a 0.2 mm thick film, the breaking strength retention (%) is defined as B1/B0×100, B1 is a breaking strength (MPa) measured at 23° C. after the film is immersed in ethanol at 130° C. for 120 hours; and B0 is a breaking strength (MPa) measured at 23° C. before immersion in ethanol.
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
Provided is a resin composition containing a woody biomass roasted product excellent in moldability and impact resistance while suppressing the content of a synthetic resin derived from petroleum resources according to the carbon neutral theory. The present invention provides a resin composition containing a woody biomass roasted product (A) and a thermoplastic resin (B), wherein: the thermoplastic resin (B) contains a polypropylene-based resin (B1) and a copolymerized polyolefin resin (B2); the mass ratio (B2/(B1 + B2)) of the copolymerized polyolefin resin (B2) to the total mass of the polypropylene-based resin (B1) and the copolymerized polyolefin resin (B2) is more than 0.00 and less than 0.80; and the mass ratio (B2/A) of the copolymerized polyolefin resin (B2) to the woody biomass roasted product (A) is more than 0.00 and less than 1.00. Note that the copolymerized polyolefin resin (B2) excludes the polypropylene-based resin (B1).
C08L 97/02 - Matériau lignocellulosique, p. ex. bois, paille ou bagasse
C08L 23/00 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères
C08L 23/10 - Homopolymères ou copolymères du propylène
C08L 23/16 - Copolymères de l’éthylène et du propylène ou de l’éthylène, du propylène et de diène
C08L 23/20 - Homopolymères ou copolymères d'hydrocarbures contenant au moins quatre atomes de carbone contenant de quatre à neuf atomes de carbone
C08L 23/26 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères modifiées par post-traitement chimique
C08L 35/00 - Compositions contenant des homopolymères ou des copolymères de composés possédant un ou plusieurs radicaux aliphatiques non saturés, chacun ne contenant qu'une seule liaison double carbone-carbone l'un au moins étant terminé par un radical carboxyle et contenant au moins un autre radical carboxyle dans la molécule, ou leurs sels, anhydrides, esters, amides, imides ou nitrilesCompositions contenant des dérivés de tels polymères
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
C08L 101/02 - Compositions contenant des composés macromoléculaires non spécifiés caractérisées par la présence de groupes déterminés
22.
BINDER FOR ENERGY STORAGE DEVICE, ELECTRODE FOR ENERGY STORAGE DEVICE, ENERGY STORAGE DEVICE, POLYMER COMPOSITE, AND PRODUCTION METHOD OF BINDER FOR ENERGY STORAGE DEVICE
A binder for an energy storage device including a polymer composite formed by compositing a polyimide precursor and/or a polyimide with a cyclic molecule having multiple ether bonds. The polyimide precursor contains a reactant of a tetracarboxylic acid component and a diamine component. The polyimide is obtained by imidizing a part or all of the polyimide precursor.
The present invention addresses the problem of providing a hydroxylase having high L-pipecolic acid hydroxylation activity for efficiently producing high-purity hydroxy-L-pipecolic acid at low cost and with high productivity. It has been found that the effects of increasing the yield of a solubilizing enzyme when a hydroxylase (McPH) is expressed in cells, improving the L-pipecolic acid hydroxylation activity of the enzyme itself, and reducing the activity of converting L-proline into hydroxy-L-proline are obtained by identifying an amino acid residue capable of affecting an improvement in the hydroxylation activity of the hydroxylase, and introducing a mutation into the identified amino acid residue.
C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression
C12P 17/12 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle l'azote comme unique hétéro-atome du cycle contenant un hétérocycle à six chaînons
24.
L-PIPECOLIC ACID HYDROXYLASE AND METHOD FOR PRODUCING HYDROXY-L-PIPECOLIC ACID
The present invention addresses the problem of providing a stable hydroxylase having high L-pipecolic acid hydroxylation activity and high stability by introducing a mutation into an L-pipecolic acid hydroxylase. It has been found that the effects of improving the L-pipecolic acid hydroxylation activity and stability of a hydroxylase (McPH) when the hydroxylase is expressed in a host such as E. coli can be obtained by identifying an amino acid residue that can affect an improvement in the hydroxylation activity and stability of the hydroxylase, and introducing a mutation into the identified amino acid residue.
C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression
C12P 17/12 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle l'azote comme unique hétéro-atome du cycle contenant un hétérocycle à six chaînons
25.
POLYIMIDE FILM PRODUCTION METHOD AND POLYIMIDE FILM
Disclosed is a method for producing an aromatic polyimide film having improved light transmittance. This method for producing a polyimide film comprises: a step (1) for applying, onto a support base material, a polyimide precursor composition that is obtained by reacting a tetracarboxylic acid component which contains an aromatic tetracarboxylic dianhydride and a diamine component which contains an aromatic diamine; a step (2) for removing a solvent from the applied polyimide precursor composition; a step (3) for imidizing the polyimide precursor composition to obtain a polyimide film; and a step (4) for irradiating the polyimide precursor composition and/or the polyimide film with light including a wavelength of 300-500 nm, wherein step (4) is performed simultaneously with at least one step selected from step (1), step (2), and step (3), and/or is performed after at least one step selected from step (1), step (2), and step (3).
B32B 17/10 - Produits stratifiés composés essentiellement d'une feuille de verre ou de fibres de verre, de scorie ou d'une substance similaire comprenant du verre comme seul composant ou comme composant principal d'une couche adjacente à une autre couche d'une substance spécifique de résine synthétique
B32B 27/34 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyamides
C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides
H05K 1/03 - Emploi de matériaux pour réaliser le substrat
26.
LIGHT-ABSORBING MATERIAL BASED ON SILICON OXYNITRIDE, METHOD FOR PRODUCING SAME, AND COMPOSITION CONTAINING SAME
The purpose of the present invention is to provide a novel light-absorbing material based on silicon oxynitride, a method for producing the light-absorbing material, and a composition containing the light-absorbing material. Typically, the purpose of the present invention is to provide a light-absorbing material based on silicon oxynitride which has light-absorbing ability in a wavelength range up to 600 nm and has a light absorption peak at around 400 nm, a method for producing said light-absorbing material, and a composition containing said light-absorbing material. This light-absorbing material based on silicon oxynitride is characterized by including a composition based on silicon oxynitride, having light-absorbing ability in a wavelength range up to 600 nm, and having an absorption peak in the wavelength range of 300-500 nm.
The purpose of the present invention is to provide a novel light-absorbing material. The purpose of the present invention is to provide a novel light-absorbing material capable of exhibiting light absorption performance typically over a wider wavelength range. A light-absorbing material according to the present disclosure is characterized by including a silicon oxynitride-based composition represented by the compositional formula SixAlwOyNz (where x, y, and z are independent positive real numbers that are not 0, and w is an independent positive real number including 0), and further including at least one type of element different from the silicon oxynitride-based composition, the integrated value of the KM value obtained by Kubelka-Munk conversion (KM conversion) from a wavelength of 600 nm to a wavelength of 2400 nm being 700 or more when the reflection spectrum of a powder of the light-absorbing material in the ultraviolet to near-infrared region is measured by a diffuse reflection method.
C01B 21/082 - Composés contenant de l'azote et des non-métaux
C04B 35/599 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base de non oxydes à base de borures, nitrures ou siliciures à base d'oxynitrures de silicium à base d'oxynitrures d'aluminium et de silicium [SiAlON]
Provided is a continuous fiber-reinforced thermoplastic resin base material in which mechanical properties such as tensile strength and bending strength of the continuous fiber-reinforced thermoplastic resin base material are improved for each type of polyamide resin in a relative manner. The continuous fiber-reinforced thermoplastic resin base material contains a thermoplastic resin and continuous reinforcing fibers. The continuous reinforcing fibers are oriented in one direction, and the thermoplastic resin is impregnated between fibers of the continuous reinforcing fibers. The thermoplastic resin contains a polyamide resin, and the polyamide resin contains a polycondensation product of at least one type of a monomer selected from the group consisting of lactams and aminocarboxylic acids. The polyamide resin also satisfies condition (a). (a) If the amino group concentration at the terminal is denoted by A μmol/g, and the carboxyl group concentration at the terminal is denoted by C μmol/g, the value of A/(A+C) is greater than 0.50.
a(2-p-q-r)(2-p-q-r)(MV(0.5+v)(0.5+v)MIII(0.5-v)pp(MV(0.67+w)(0.67+w)MII(0.33-w)qqMIVr(14-s)(14-s)M1s(39±t)(39±t) (In the formula, A is at least one element selected from the group that consists of Li and Na, M1is selected from the group that consists of MV, (MIV(0.5+w)(0.5+w)MVI(0.5-w)(0.5-w)), (MVI(0.67+w)(0.67+w)MIII(0.33-w)(0.33-w)), and (MVI(0.75+w)(0.75+w)MII(0.25-w)(0.25-w)), each MIIis independently at least one divalent metal element, each MIIIis independently at least one trivalent metal element, each MIVis independently at least one tetravalent metal element, each MVis independently at least one pentavalent metal element, each MVI is independently at least one hexavalent metal element, 0≤a≤6, -0.05≤v≤0.05, -0.05≤w≤0.05, 0≤p<2, 0≤q<2, 0≤r<2, 0
H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
H01M 4/131 - Électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p. ex. LiCoOx
H01M 4/485 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'oxydes ou d'hydroxydes mixtes pour insérer ou intercaler des métaux légers, p. ex. LiTi2O4 ou LiTi2OxFy
A gas separation system for producing a CH4-enriched gas from a feedstock gas containing CO2 and CH4, including a first gas separation membrane unit and a second gas separation membrane unit, in which the gas separation system includes a feedstock gas supply line connected to a gas inlet of the first gas separation membrane unit; a compression part disposed in the feedstock gas supply line; a first line connecting the retentate gas outlet of the first gas separation membrane unit and the gas inlet of the second gas separation membrane unit; a second line connecting the permeate gas outlet of the second gas separation membrane unit and the feedstock gas supply line; and a cooling part for lowering the operating temperature of the second gas separation membrane unit below the operating temperature of the first gas separation membrane unit.
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
C07C 7/00 - Purification, séparation ou stabilisation d'hydrocarburesEmploi d'additifs
C07C 7/144 - Purification, séparation ou stabilisation d'hydrocarburesEmploi d'additifs par emploi de membranes, p. ex. par perméation sélective
31.
SILICON NITRIDE POWDER FOR 3D FABRICATION, RESIN COMPOSITION, PRECURSOR, SILICON NITRIDE-BASED SINTERED BODY, ARTICLE, METHOD FOR PRODUCING RESIN COMPOSITION, AND METHOD FOR PRODUCING SILICON NITRIDE-BASED SINTERED BODY
The purpose of the present invention is to provide: silicon nitride powder suitable for 3D fabrication, capable of achieving both light transmittance and sinterability; a resin composition including the powder; a precursor obtained from the composition; and a silicon nitride-based sintered body obtained from the precursor. The silicon nitride powder for 3D fabrication is characterized in that: in a volume-based particle size distribution measured by particle size distribution measurement, when the particle diameter range of 0.5 μm or more and 1.5 μm or less is defined as a range S, and the particle diameter range of more than 1.5 μm and 5.5 μm or less is defined as a range L, the ratio (Sint/Lint) of an area (Sint) of the range S to an area (Lint) of the range L is 5.7 or less; an oxide film containing silicon oxide and/or silicon oxynitride is formed on a particle surface corresponding to the range S; and the thickness of the oxide film is 0.5-5.5 nm. Also provided are: a resin composition including the powder; a precursor obtained from the composition; and a silicon nitride sintered body obtained from the precursor.
C01B 21/068 - Composés binaires de l'azote avec les métaux, le silicium ou le bore avec le silicium
B28B 1/30 - Fabrication d'objets façonnés à partir du matériau en appliquant le matériau sur un noyau ou une autre surface de moulage pour former une couche sur celle-ci
Provided are: a polyamide resin composition, which can provide a film that does not have poor appearance arising from film gels and has excellent transparency, puncture strength, and pinhole resistance and which makes material recycling possible; and a film and a film laminate that utilize the polyamide resin composition.
Provided are: a polyamide resin composition, which can provide a film that does not have poor appearance arising from film gels and has excellent transparency, puncture strength, and pinhole resistance and which makes material recycling possible; and a film and a film laminate that utilize the polyamide resin composition.
A polyamide resin composition comprising, with respect to 100 mass % of the polyamide resin composition, 70-95 mass % of an aliphatic polyamide resin (A), 5-30 mass % of an ethylene/C3-C8 α-olefin copolymer (B) that has functional groups, and 0-5 mass % of another component (C), wherein: the ratio of the number of methylene groups to the number of amide groups in the aliphatic polyamide resin (A) is 3-11; and when the number average molecular weight and weight average molecular weight by GPC measurement of the polyamide resin composition are Mn and Mw, respectively, Mn is 25,000-46,000, and Mw/Mn is 1.5-3.0.
The present invention relates to a polyether polycarbonate diol, an application thereof, and a manufacturing method for the same. The polyether polycarbonate diol has a structural unit derived from polypropylene glycol and a structural unit derived from a linear aliphatic diol. The integrated value of 1H-NMR satisfies formula (1): 0.3450 ≤ A/(A + B/2) ≤ 0.3800 [in formula (1), A is the integrated value of peaks included in 3.85 to 4.02 ppm, and B is the integrated value of peaks included in 1.51 to 1.62 ppm], and the polyether polycarbonate diol can control a urethanization reaction if used in the manufacture of a polyurethane resin.
CRYSTALLINE SILICON NITRIDE POWDER, SILICON NITRIDE SINTERED BODY CONTAINING SAID POWDER, METHOD FOR PRODUCING SILICON NITRIDE SINTERED BODY, ARTICLE CONTAINING SAID SINTERED BODY, AND VEHICLE
The present invention, by including a specific amount of impurity carbon, provides a crystalline silicon nitride powder that is easily sintered and makes it possible to produce a silicon nitride sintered body having excellent mechanical strength or thermal conductivity. Also provided by using this silicon nitride powder is a silicon nitride sintered body that is easily sintered and has excellent mechanical strength or thermal conductivity. The present invention also provides a method for producing a silicon nitride sintered body that is easily sintered and has excellent mechanical strength or thermal conductivity. Provided is a crystalline silicon nitride powder containing silicon nitride, carbon, and oxygen, in which the mass ratio Cp of the carbon to the whole powder is 0.200 mass% or less, the mass ratio C1 of a first volatile carbon detected at from 100°C to less than 700°C measured by temperature-programmed morphology analysis is from 0.001 mass% to 0.030 mass%, and the mass ratio C2 of a second volatile carbon detected at from 700°C to 1200°C measured by temperature-programmed morphology analysis from 0.005 mass% to 0.060 mass%.
[Object] To provide a more useful antitumor drug that is more advanced than a conventional antibody-drug conjugate.
[Object] To provide a more useful antitumor drug that is more advanced than a conventional antibody-drug conjugate.
[Solution] An antibody multi-drugs conjugate represented by a following General Formula (I):
[Object] To provide a more useful antitumor drug that is more advanced than a conventional antibody-drug conjugate.
[Solution] An antibody multi-drugs conjugate represented by a following General Formula (I):
[wherein the symbols have the meanings described in Description of the present application],
or a pharmacologically acceptable salt thereof.
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
C07K 16/32 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des produits de traduction des oncogènes
37.
GAS SEPARATION MEMBRANE UNIT, GAS SEPARATION SYSTEM, AND METHOD FOR PRODUCING ENRICHED GAS
Provided are: a gas separation membrane unit capable of performing gas separation that exhibits excellent recovery rate and purity of a product gas; and a gas separation system using the same. The gas separation membrane unit is supplied with a raw material mixture gas, and concentrates and enriches at least one of the gases included in the raw material mixture gas. The gas separation membrane unit is formed by combining, in parallel, a plurality of gas separation membrane modules. Each of the plurality of gas separation membrane modules has a gas inlet, an impermeable gas outlet, and a permeable gas outlet. The gas inlet, the impermeable gas outlet, and the permeable gas outlet of each of the modules are shared, thereby constituting the gas inlet, the impermeable gas outlet, and the permeable gas outlet of the gas separation membrane unit. The variation coefficient of gas separation selectivity or gas permeability of the plurality of gas separation membrane modules is 0.01-0.49.
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
The present invention pertains to an aqueous polyurethane resin dispersion in which particles of a polyurethane resin (A) are dispersed in an aqueous medium (B), The polyurethane resin (A) has a structure derived from an acidic group-free polyol (a), a structure derived from a polyisocyanate (b), and a structure derived from an acidic group-containing polyol (c); the average particle diameter of the particles of the polyurethane resin (A) is 30-80 nm, the average particle diameter being obtained by dynamic light scattering; the acidic group-free polyol (a) contains a polycarbonate polyol; and a film having a thickness of 40 μm obtained by heating the aqueous polyurethane resin dispersion for 2 hours at 60°C and then heating at 120°C for 2 hours has an elastic modulus of 400-900 MPa. The aqueous polyurethane resin dispersion can contribute to the achievement of Goal 7 of Sustainable Development Goals (SDGs), for example.
A unit (gas separation membrane unit; the same applies hereinafter) (11) and a unit (12) are connected by a line (14). The unit (11) and a unit (13) are connected by a transmission gas line (15). A raw material mixed gas supply line (16) is connected to the unit (11), and a compression means (21) is interposed in the middle of the line (16). A transmission gas line (70) is connected to the unit (13). The gas separation membrane unit (12) and the line (16) are connected by a permeate-gas recycling line (17). The gas separation membrane unit (13) and the line (16) are connected by a non-permeate-gas recycling line (18). A permeate gas line (70) has a flow channel through which some permeate gas discharged from the unit (13) can be refluxed to the line (16). Concentrated enriched gas is taken out from the unit (12).
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
Provided is a polyamide resin composition for a single-layer hollow molded body having polyamide 6 as the main component, substantially without using polyamide 11 and polyamide 12, wherein the properties are equivalent to those of a multilayered hollow molded body, the extrusion moldability of the hollow molded body is excellent, and the flexibility, impact resistance, and durability of the obtained molded body are excellent.
Provided is a polyamide resin composition for a single-layer hollow molded body having polyamide 6 as the main component, substantially without using polyamide 11 and polyamide 12, wherein the properties are equivalent to those of a multilayered hollow molded body, the extrusion moldability of the hollow molded body is excellent, and the flexibility, impact resistance, and durability of the obtained molded body are excellent.
The polyamide resin composition is a polyamide resin composition for extrusion molding to produce a single-layer hollow molded body, which contains polyamide 6 (a), a polyolefin (b) having a functional, and a plasticizer (c); the relative viscosity of the polyamide 6 (a), measured at 25° C. when I g of the polyamide 6 (a) is dissolved in 100 mL of 96% sulfuric acid in accordance with JIS K6920, is 3.0-4.5; 100 mass % of polyamide resin composition contains 60-90 mass % of the polyamide 6 (a), 3-25 mass % of the polyolefin (b) having a functional group, and 3-20 mass % of the plasticizer (c); and the polyolefin (b) having a functional group is a copolymer of ethylene and a C4 or higher α-olefin having a group derived from at least one selected from the group consisting of maleic anhydride and itaconio anhydride.
Provided is an oxetanyl-modified polycarbonate polyol that, when used as an additive for producing a cationically-curable resin, can provide good solvent resistance to the resin.
A transition metal composite oxide powder containing at least niobium and a trivalent element MIIIselected from among aluminum, iron and chromium, said powder being characterized in that the molar ratio Nb/MIIIof niobium relative to the trivalent element MIIIis 8≤Nb/MIII10901050509090 represents the particle size at the point at which the cumulative volume distribution of particle sizes of the primary particles in the particle-size distribution reaches 90%.)
H01M 4/131 - Électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p. ex. LiCoOx
H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
H01M 4/485 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'oxydes ou d'hydroxydes mixtes pour insérer ou intercaler des métaux légers, p. ex. LiTi2O4 ou LiTi2OxFy
H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
12322-, or a hydrocarbon group having 8-24 carbon atoms and having an aromatic ring and an alkylene group; a hydrogen atom of the hydrocarbon group may be substituted with a hydroxy group; a represents an integer of 0-3; b represents an integer of 0-2; c represents an integer of 0-3; and n represents an integer of 0-10.
C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
C08G 10/00 - Polymères de condensation obtenus uniquement à partir d'aldéhydes ou de cétones avec des hydrocarbures aromatiques ou avec leurs dérivés halogénés
C08G 59/40 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les agents de durcissement utilisés
H01L 23/29 - Encapsulations, p. ex. couches d’encapsulation, revêtements caractérisées par le matériau
H01L 23/31 - Encapsulations, p. ex. couches d’encapsulation, revêtements caractérisées par leur disposition
45.
METHOD FOR PRODUCING SOLUBILIZED KERATIN AQUEOUS SOLUTION AND SOLUBILIZED KERATIN, SOLUBILIZED KERATIN AQUEOUS SOLUTION AND SOLUBILIZED KERATIN, AND MOLDED ARTICLE AND COMPOSITION COMPRISING SOLUBILIZED KERATIN
In this method for producing a solubilized keratin aqueous solution, keratin fibers and water with a pH of 6-8 are brought into contact with each other in a reactor heated to 135-230°C at a mass ratio of the water to the keratin fibers (water/keratin fibers) of at least 1 but less than 18.
The present invention provides: a crystalline silicon nitride powder which makes it possible to obtain a silicon nitride-based sintered body that has high strength, low variability, and excellent properties as a sintered body; a silicon nitride-based sintered body which has high strength and low variability; and a method for producing the silicon nitride-based sintered body. Provided are: a crystalline silicon nitride powder characterized in that the amount of metal foreign matter of more than 20 μm present in 1 kg of the crystalline silicon nitride powder is 10-200 μg in a specific measurement method, and that in 1 cm3 of the crystalline silicon nitride powder, when said amount of metal foreign matter is converted as a 40-μm diameter, the total number of particles of the metal foreign matter, coarse particles of 3 to 50 μm, and aggregated particles and/or fused particles is less than 160; a silicon nitride-based sintered body obtained by sintering said crystalline silicon nitride powder; and a method for producing a silicon nitride-based sintered body characterized by comprising a step for molding and sintering a sintering raw material which contains said crystalline silicon nitride powder and a sintering aid.
Provided is a dispersion containing poly(amic acid)/carbon nanotubes which comprises an organic solvent, a poly(amic acid), and carbon nanotubes, the poly(amic acid) having an alicyclic structure. When having a carbon nanotube concentration of 0.001 mass%, the dispersion containing poly(amic acid)/carbon nanotubes has an optical density at 500-nm wavelength exceeding 0.40.
The purpose of the present invention is to provide a cartilage tissue body that has a sufficient mechanical strength and thickness, that does not contain scaffold components derived from other animals, and that is highly safe. The present invention provides a method for producing a scaffold-free three-dimensional cartilage tissue, the method comprising a step for culturing a modularized polyimide porous membrane on which chondrocytes are seeded while allowing the membrane to float in a culture medium in a state in which the membrane is not fixed in a cell culture vessel for floating culture, while having shear stress applied to the modularized polyimide porous membrane. The present invention also provides: a scaffold-free three-dimensional cartilage tissue body; and a modularized polyimide porous membrane for producing a scaffold-free three-dimensional cartilage tissue body.
The present invention is a polyamide resin composition containing (A) an aliphatic polyamide resin and (B) an epoxy group-containing elastomer, wherein: the aliphatic polyamide resin (A) is an aliphatic polyamide resin in which the ratio of the number of methylene groups to the number of amide groups is more than 5.0; when the amino group amount of the aliphatic polyamide resin (A) blended in 1 kg of the resin composition is denoted as X mmol and the epoxy group amount of the epoxy group-containing elastomer (B) blended in 1 kg of the resin composition is denoted as Z mmol, formula (1): 1.05 ≤ [Z]/[X] ≤ 3.40, formula (2): 10.0 ≤ [X] ≤ 45.0, and formula (3): 20.0 ≤ [Z] ≤ 80.0 are satisfied; and a molded article including the polyamide resin composition can contribute to achievement of goals 9, 13, and the like of sustainable development goals (SDGs) by virtue of weight reduction of the molded article, from the viewpoint of contributing to reduction in resource usage.
C08L 63/00 - Compositions contenant des résines époxyCompositions contenant des dérivés des résines époxy
C08L 77/00 - Compositions contenant des polyamides obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
F16L 11/04 - Manches, c.-à-d. tuyaux flexibles en caoutchouc ou en matériaux plastiques flexibles
The present invention relates to a polyamide resin composition which contains: an aliphatic polyamide resin (Aa) comprising an aliphatic homopolyamide resin (A-1) and an aliphatic copolyamide resin (A-2); an aromatic polyamide resin (Ab); an ionomer (B); and a functional group-containing olefin-based resin (C). 100 mass% of the polyamide resin composition includes 40-60 mass% of the aliphatic homopolyamide resin (A-1), 10-40 mass% of the aliphatic copolyamide resin (A-2), 2-10 mass% of the aromatic polyamide resin (Ab), 5-20 mass% of the ionomer (B) and 5-10 mass% of the functional group-containing olefin-based resin (C). The relative viscosity of the aliphatic polyamide resin (Aa), as measured at 25ºC after dissolving 1 g of the aliphatic polyamide resin (Aa) in 100 mL of 96% sulfuric acid in accordance with JIS K 6920, is 3.60 to 3.85.
C08L 77/00 - Compositions contenant des polyamides obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
C08L 23/26 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères modifiées par post-traitement chimique
52.
THERAPEUTIC DRUG FOR CHRONIC KIDNEY DISEASE, AND SCREENING METHOD FOR THERAPEUTIC DRUG FOR CHRONIC KIDNEY DISEASE
Provided are: a therapeutic drug for chronic kidney disease, which is capable of significantly improving the chronic kidney disease; and a screening method for a therapeutic drug for chronic kidney disease. This therapeutic drug for chronic kidney disease comprises an Nrf2 activator to be used in combination with a renin-angiotensin inhibitor. This therapeutic drug for chronic kidney disease comprises a renin-angiotensin inhibitor to be used in combination with an Nrf2 activator. This therapeutic drug for chronic kidney disease comprises a renin-angiotensin inhibitor and an Nrf2 activator.
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61K 31/553 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant au moins un azote et au moins un oxygène comme hétéro-atomes d'un cycle, p. ex. loxapine, staurosporine
A61K 31/4178 - 1,3-Diazoles non condensés et contenant d'autres hétérocycles, p. ex. pilocarpine, nitrofurantoïne
A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
53.
CONJUGATE OF ANTI-CDH3 HUMANIZED ANTIBODY AND DRUG, AND USE THEREOF
The present invention addresses the problem of providing a novel anti-CDH3 humanized antibody-drug conjugate. Provided according to the present invention is an antibody-drug conjugate in which an anti-CDH3 humanized antibody is linked with a chemotherapeutic agent having a linker, wherein the anti-CDH3 humanized antibody is (1) an anti-CDH3 humanized antibody having a heavy chain variable region comprising an amino acid sequence set forth in SEQ ID NO: 1 and a light chain variable region comprising an amino acid sequence set forth in SEQ ID NO: 2, (2) an anti-CDH3 humanized antibody having a heavy chain variable region comprising an amino acid sequence set forth in SEQ ID NO: 3 and a light chain variable region comprising an amino acid sequence set forth in SEQ ID NO: 4, etc., the chemotherapeutic having a linker is represented by formula (x): (in the formula, * indicates the connection with the antibody.), etc.
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A61K 47/55 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique l’agent de modification étant aussi un agent pharmacologiquement ou thérapeutiquement actif, c.-à-d. le conjugué entier étant un co-médicament, p. ex. un dimère, un oligomère ou un polymère de composés pharmacologiquement ou thérapeutiquement actifs
A61K 47/60 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique macromoléculaire, p. ex. une molécule oligomérique, polymérique ou dendrimérique obtenu par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyurées ou polyuréthanes le composé organique macromoléculaire étant un oligomère, un polymère ou un dendrimère de polyoxyalkylène, p. ex. PEG, PPG, PEO ou polyglycérol
A61K 47/65 - Séquences de liaison, liants ou bras-espaceurs peptidiques, p. ex. séquences de liaison peptidiques vulnérable aux protéases
C07K 16/18 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
54.
THERMOPLASTIC RESIN COMPOSITION AND PELLET MIXTURE
The present invention provides: a thermoplastic resin composition which is capable of improving impact resistance while maintaining flexural strength when formed into a molded article; and a pellet mixture which is suitable for use for the production of the composition. The present invention specifically provides a thermoplastic resin composition which contains a thermoplastic resin (A), cellulose-based fibers (B), and reinforcing fibers (C). The reinforcing fibers (C) are other than the cellulose-based fibers (B), and the average fiber length of the reinforcing fibers (C) is 500 μm or more and 1,200 μm or less.
C08L 1/00 - Compositions contenant de la cellulose, de la cellulose modifiée ou des dérivés de la cellulose
C08L 77/00 - Compositions contenant des polyamides obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
B29K 105/12 - Présentation, forme ou état de la matière moulée contenant des agents de renforcement, charges ou inserts de longueur réduite, p. ex. filaments coupés, fibres coupées ou crins
55.
POLYAMIDE RESIN COMPOSITION, MOLDED BODY, FLUIDITY MODIFIER, AND BINDER RESIN
The present invention relates to a polyamide resin composition which contains a polyamide resin (A), wherein: the polyamide resin (A) contains a polyamide resin (A-1) that has an alkyl group at an end and a polyamide resin (A-2) that has an arylene group at an end; and the terminal amino group concentration of the polyamide resin (A) is 0.10 μmol/g or less. The present invention also relates to a fluidity modifier for a thermoplastic resin (B), the fluidity modifier comprising only the polyamide resin (A). A molded body that contains the polyamide resin composition can contribute to the achievement of goals 9, 13, and the like of the sustainable development goals (SDGs) from the viewpoint of contributing to a reduction in resource usage by reducing the weight of the molded body.
Provided is a polyimide resin powder which contains a tetracarboxylic acid component and a diamine component. The tetracarboxylic acid component includes 3,3',4,4'-biphenyltetracarboxylic acid dianhydride and 2,3,3',4'-biphenyltetracarboxylic acid dianhydride. The diamine component includes p-phenylenediamine and m-phenylenediamine and/or 4,4'-diaminodiphenyl ether. The content of p-phenylenediamine is 70-98 mol% based on the total molar amount of the diamine component. The total content of m-phenylenediamine and 4,4'-diaminodiphenyl ether is 2-30 mol% based on the total molar amount of the diamine component.
Provided is a resin composition containing: a polycarbonate polyol (A) in which the number of terminal hydroxyl groups is greater than 2; and an epoxy group–containing compound (B) and/or an oxetane compound (C). The resin composition is used in 3D printer applications.
B33Y 80/00 - Produits obtenus par fabrication additive
C08L 63/00 - Compositions contenant des résines époxyCompositions contenant des dérivés des résines époxy
C08L 71/00 - Compositions contenant des polyéthers obtenus par des réactions créant une liaison éther dans la chaîne principaleCompositions contenant des dérivés de tels polymères
Provided is a resin composition containing a monofunctional oxetane compound (A), an aromatic bisoxetane compound (B), and a polycarbonate polyol (C). The polycarbonate polyol (C) content is 1-25 mass% relative to the total mass of the resin composition. The resin composition is used in 3D printer applications.
C08L 71/00 - Compositions contenant des polyéthers obtenus par des réactions créant une liaison éther dans la chaîne principaleCompositions contenant des dérivés de tels polymères
The present invention provides: a compound having an LPA receptor antagonistic activity; and a pharmaceutical composition containing the compound. Specifically, the present invention provides: a compound represented by general formula (I) [wherein the symbols have the meanings set forth in the description] or a deuterated product thereof, or a pharmaceutically acceptable salt of the compound or the deuterated product; and a pharmaceutical composition containing the compound, the deuterated product, or the pharmaceutically acceptable salt.
C07D 205/04 - Composés hétérocycliques comportant des cycles à quatre chaînons ne contenant qu'un atome d'azote comme unique hétéro-atome du cycle non condensés avec d'autres cycles ne comportant pas de liaison double entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques
A61K 31/397 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à quatre chaînons, p. ex. azétidine
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
A61K 31/422 - Oxazoles non condensés et contenant d'autres hétérocycles
A61K 31/4418 - Pyridines non condenséesLeurs dérivés hydrogénés ayant un carbocycle lié directement à l'hétérocycle, p. ex. cyproheptadine
A61K 31/4427 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
A61K 31/451 - Pipéridines non condensées, p. ex. pipérocaïne ayant un carbocycle lié directement à l'hétérocycle, p. ex. glutéthimide, mépéridine, lopéramide, phencyclidine, piminodine
A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine
A61K 31/497 - Pyrazines non condensées contenant d'autres hétérocycles
A61K 31/501 - PyridazinesPyridazines hydrogénées non condensées et contenant d'autres hétérocycles
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61P 25/04 - Analgésiques centraux, p. ex. opioïdes
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
C07D 207/16 - Atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
C07D 211/64 - Atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile liés en position 4 comportant un radical aryle comme second substituant en position 4
C07D 401/04 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 401/06 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
C07D 401/12 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
C07D 401/14 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant au moins trois hétérocycles
C07D 403/04 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 403/06 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée ne contenant que des atomes de carbone aliphatiques
C07D 405/04 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 405/06 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
C07D 409/04 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 413/04 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 417/04 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 417/14 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant au moins trois hétérocycles
60.
POLYIMIDE PRECURSOR COMPOSITION AND METHOD FOR PRODUCING THE SAME
A polyimide precursor for producing a flexible electronic device substrate that provides a polyimide with reduced charge-up, particularly a polyimide in the form of a film. When a polyimide film having a thickness of 10 μm is formed using the polyimide precursor, and a pair of electrodes is formed with a distance d on the polyimide film, and when the polyimide film is irradiated with a laser beam while applying a DC voltage with an electric field strength of 0.1 to 10 V/μm between the pair of electrodes; two SHG lights are observed between the pair of electrodes and satisfy a symmetry ratio of 0.5 or more. The symmetry ratio (LR ratio)=Ismall/Ilarge, wherein, Ilarge represents the peak intensity of the SHG light with the larger intensity, and Ismall represents the peak intensity of the SHG light with the smaller intensity.
An object of the present invention is to provide a method of industrially producing a high-purity L-cyclic amino acid more inexpensively and with a high efficiency, from a cyclic amino acid having a double bond at the 1-position. The present invention provides a method in which an L-cyclic amino acid is produced by allowing a cyclic amino acid having a double bond at the 1-position to react with a specific enzyme having a catalytic ability to reduce a cyclic amino acid having a double bond at the 1-position to produce an L-cyclic amino acid.
A novel linker, a linker-payload, and an antibody-drug conjugate, as well as an antitumor drug. An antibody-drug conjugate of formula (I) or a pharmacologically acceptable salt thereof, or a hydrate thereof,
A novel linker, a linker-payload, and an antibody-drug conjugate, as well as an antitumor drug. An antibody-drug conjugate of formula (I) or a pharmacologically acceptable salt thereof, or a hydrate thereof,
A-(B-L-D)a (I)
A novel linker, a linker-payload, and an antibody-drug conjugate, as well as an antitumor drug. An antibody-drug conjugate of formula (I) or a pharmacologically acceptable salt thereof, or a hydrate thereof,
A-(B-L-D)a (I)
where A is an antibody residue in which functional group(s) in antibody involved in binding to linker(s) is/are removed from an antibody which can target a tumor cell; B is a divalent group derived from the functional group in antibody; a is an integer of 1 to 10; D is an antitumor drug residue in which one hydrogen atom or one hydroxy group is removed from any position of an antitumor drug molecule or an analog thereof, or a derivative thereof, L is a linker which links B to D; and at least any one of D and L has one or more lactonyl group(s) as substituent(s) or protecting group(s) at any position(s).
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
C07K 16/32 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des produits de traduction des oncogènes
63.
GAS SEPARATION SYSTEM AND METHOD FOR PRODUCING METHANE ENRICHED GAS
4244, said gas separation system 10 comprising: a feedstock gas supply line 26 which is connected to a gas inlet 11a of the first gas separation membrane unit 11; a compression means 21 which is disposed in the feedstock gas supply line 26; a first line 14 which connects a non-permeating gas outlet 11b of the first gas separation membrane unit 11 and a gas inlet 12a of the second gas separation membrane unit 12; and a second line 17 which connects a permeating gas outlet 12c of the second gas separation membrane unit 12 and the feedstock gas supply line 26, wherein a cooling means 22 that reduces the operating temperature of the second gas separation membrane unit as compared to the operating temperature of the first gas separation membrane unit is provided.
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
64.
Gas separation system and method for producing methane-enriched gas
A gas separation system for enriching methane contained in raw material mixed gas including at least carbon dioxide and methane by supplying the raw material mixed gas to a gas separation membrane unit in which the gas separation system includes a first gas separation membrane unit and a second gas separation membrane unit. A raw material mixed gas supply line is connected to a gas inlet of the first gas separation membrane unit. The non-permeated gas outlet of the first gas separation membrane unit and the gas inlet of the second gas separation membrane unit are connected by a first non-permeated gas discharge line. A second non-permeated gas recovery line is connected to the second non-permeated gas outlet of the second gas separation membrane unit. The first permeated gas outlet of the first gas separation membrane unit and the second permeated gas outlet of the second gas separation membrane unit are connected to the raw material mixed gas supply line by a first permeated gas recycle line and a second permeated gas recycle line, respectively. The line includes a permeated gas discharge line for at least partially discharging the permeated gas of the first gas separation membrane unit to the outside of the system.
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
In the formula, more than 0 mol % and less than 30 mol % of Y1 is represented by the formula (1):
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
In the formula, more than 0 mol % and less than 30 mol % of Y1 is represented by the formula (1):
in formula (1), A is a structure represented by formula (A):
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
In the formula, more than 0 mol % and less than 30 mol % of Y1 is represented by the formula (1):
in formula (1), A is a structure represented by formula (A):
n is 1 to 4, m is 0 to 4, B is an alkyl group having 1 to 6 carbon atoms, and U is —CO—O— or —O—CO—.
C08G 69/26 - Polyamides dérivés, soit des acides amino-carboxyliques, soit de polyamines et d'acides polycarboxyliques dérivés de polyamines et d'acides polycarboxyliques
The present invention relates to a thermoplastic resin composition containing a thermoplastic resin (A) and a cellulose-based fiber (B) having an average fiber length of 2-1,000 μm, wherein, in a type A1 specimen prepared from the thermoplastic resin composition according to ISO 294-1, the number of agglomerates of the cellulose-based fiber (B) that exceed 100 μm × 100 μm is at most 2 per 30 mm2. The thermoplastic resin composition has excellent tensile fracture strain. In addition, the thermoplastic resin composition can contribute to achieving Goals 9, 13, etc. of Sustainable Development Goals (SDGs) in terms of contributing to a reduction in resource consumption by making a molded product therefrom lightweight.
This polyurethane resin has allophanate bonds, and the proportion of the allophanate bonds in 100 mass% of the polyurethane resin is 0.10 mass% to 4.5 mass%.
C08G 18/78 - Polyisocyanates ou polyisothiocyanates contenant des hétéro-atomes autres que l'azote, l'oxygène ou le soufre de l'isocyanate ou de l'isothiocyanate de l'azote
C08G 18/00 - Polymérisats d'isocyanates ou d'isothiocyanates
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
In the formula, 70 mol % to 90 mol % of X1 is a group represented by following formula (21), and 10 to 30 mol % is a group represented by following formula (22) and/or a group represented by following formula (23),
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
In the formula, 70 mol % to 90 mol % of X1 is a group represented by following formula (21), and 10 to 30 mol % is a group represented by following formula (22) and/or a group represented by following formula (23),
45 mol % to 100 mol % of Y1 is a group represented by the formula (1):
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
In the formula, 70 mol % to 90 mol % of X1 is a group represented by following formula (21), and 10 to 30 mol % is a group represented by following formula (22) and/or a group represented by following formula (23),
45 mol % to 100 mol % of Y1 is a group represented by the formula (1):
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
In the formula, 70 mol % to 90 mol % of X1 is a group represented by following formula (21), and 10 to 30 mol % is a group represented by following formula (22) and/or a group represented by following formula (23),
45 mol % to 100 mol % of Y1 is a group represented by the formula (1):
and in formula (1), A is a structure represented by formula (A):
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
In the formula, 70 mol % to 90 mol % of X1 is a group represented by following formula (21), and 10 to 30 mol % is a group represented by following formula (22) and/or a group represented by following formula (23),
45 mol % to 100 mol % of Y1 is a group represented by the formula (1):
and in formula (1), A is a structure represented by formula (A):
A polyimide precursor composition for flexible wiring boards, which contains a polyimide precursor having a repeating unit represented by general formula (I).
In the formula, 70 mol % to 90 mol % of X1 is a group represented by following formula (21), and 10 to 30 mol % is a group represented by following formula (22) and/or a group represented by following formula (23),
45 mol % to 100 mol % of Y1 is a group represented by the formula (1):
and in formula (1), A is a structure represented by formula (A):
in which n is 1 to 4, m is 0 to 4, B is an alkyl group having 1 to 6 carbon atoms, and U represents —CO—O— or —O—CO—.
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japon)
KYOTO UNIVERSITY (Japon)
Inventeur(s)
Ikuta Junya
Tateishi Chuya
Fujimori Kazuhiro
Umemura Maiko
Araki Michihiro
Kuriya Yuki
Yamamoto Masaki
Abrégé
The purpose of the present invention is to provide: a new aminotransferase capable of improving the production efficiency of an amino compound; or a transformant having the same. The purpose of the present invention is to also provide a biosynthesis method for an amino compound using said new aminotransferase or a transformant having the same. The present invention for solving the problem is an aminotransferase that uses a carbonyl compound as a substrate, and that is characterized by having an amino acid sequence that has an identity of 90% or more with respect to any one of the amino acid sequences of SEQ ID NO: 13, 17, 21, 25, and 29. The carbonyl compound is preferably a compound represented by formula (1). The present invention makes it possible to supply bio-derived products and can realize carbon recycling, and thereby provides a contribution in achieving the Goal 12, etc., of the SDGs. In formula (1), R represents a methyl group or an ethyl group. n represents an integer of 2-16.
The present invention relates to: a first polyurethane resin dispersion composition that includes a polyurethane resin (A), an anionic surfactant (B), a polyhydroxy compound (C) that has at least one triple bond, and an aqueous medium (D); a thickening inhibitor for a second polyurethane resin dispersion composition that includes the polyurethane resin (A) and the aqueous medium (D), the thickening inhibitor using a combination of the anionic surfactant (B) and the polyhydroxy compound (C); and a method for improving the wetting properties of the second polyurethane resin dispersion composition that uses the abovementioned combination. The first polyurethane resin dispersion composition contributes to the achievement of Goal 7 and the like of the Sustainable Development Goals (SDGs).
A method for producing a salicylic acid ester represented by general formula (2) below, in which salicylic acid and an alcohol represented by general formula (1) below are brought into contact with a solid acid catalyst at a reaction temperature of 50° C. to 200° C.
A method for producing a salicylic acid ester represented by general formula (2) below, in which salicylic acid and an alcohol represented by general formula (1) below are brought into contact with a solid acid catalyst at a reaction temperature of 50° C. to 200° C.
X—R—OH (1)
A method for producing a salicylic acid ester represented by general formula (2) below, in which salicylic acid and an alcohol represented by general formula (1) below are brought into contact with a solid acid catalyst at a reaction temperature of 50° C. to 200° C.
X—R—OH (1)
(In the formula (1), R represents a linear or branched alkyl group having 1 to 6 carbon atoms. X represents a hydrogen atom or a hydroxyl group.)
A method for producing a salicylic acid ester represented by general formula (2) below, in which salicylic acid and an alcohol represented by general formula (1) below are brought into contact with a solid acid catalyst at a reaction temperature of 50° C. to 200° C.
X—R—OH (1)
(In the formula (1), R represents a linear or branched alkyl group having 1 to 6 carbon atoms. X represents a hydrogen atom or a hydroxyl group.)
A method for producing a salicylic acid ester represented by general formula (2) below, in which salicylic acid and an alcohol represented by general formula (1) below are brought into contact with a solid acid catalyst at a reaction temperature of 50° C. to 200° C.
X—R—OH (1)
(In the formula (1), R represents a linear or branched alkyl group having 1 to 6 carbon atoms. X represents a hydrogen atom or a hydroxyl group.)
(In the formula (2), R and X are each as defined in the formula (1).)
C07C 67/08 - Préparation d'esters d'acides carboxyliques par réaction d'acides carboxyliques ou d'anhydrides symétriques avec le groupe hydroxyle ou O-métal de composés organiques
72.
POLYIMIDE PRECURSOR FOR DISPLAY SUBSTRATE, POLYIMIDE FILM FOR DISPLAY SUBSTRATE, AND DISPLAY SUBSTRATE
A polyimide precursor for a display substrate capable of forming a polyimide film for a display substrate having a charge half-life of 48 seconds or more and/or a charge decay ratio after 120 seconds of 63% or less in measurement of the charge half-life in accordance with JIS L 1094A.
C08G 73/06 - Polycondensats possédant des hétérocycles contenant de l'azote dans la chaîne principale de la macromoléculePolyhydrazidesPolyamide-acides ou précurseurs similaires de polyimides
C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides
A method for improving the stability of an antibody-drug conjugate in a living body, and a conjugate precursor for producing a stabilized antibody-drug conjugate. An antibody-drug conjugate precursor represented by the following general formula (I) or a salt thereof, a synthetic intermediate thereof or a salt thereof,
A method for improving the stability of an antibody-drug conjugate in a living body, and a conjugate precursor for producing a stabilized antibody-drug conjugate. An antibody-drug conjugate precursor represented by the following general formula (I) or a salt thereof, a synthetic intermediate thereof or a salt thereof,
Z-L-D (I)
A method for improving the stability of an antibody-drug conjugate in a living body, and a conjugate precursor for producing a stabilized antibody-drug conjugate. An antibody-drug conjugate precursor represented by the following general formula (I) or a salt thereof, a synthetic intermediate thereof or a salt thereof,
Z-L-D (I)
where Z is a reactive group which can react with a functional group present in an antibody or a modified antibody; D is an antitumor drug residue in which one hydrogen atom or one hydroxy group is removed from any position of an antitumor drug molecule or an analog thereof or a derivative thereof; L is a linker which links Z to D; and at least any one of D and L has one or more lactonyl group(s) at any position(s) as substituent(s) or protecting group(s).
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
A polyimide precursor for a display substrate capable of forming a polyimide film for a display substrate having a charge half-life of 48 seconds or more and/or a charge decay ratio after 120 seconds of 63% or less in measurement of the charge half-life in accordance with JIS L 1094A.
Provided is a polyamide resin composition which is shiny and has good mechanical properties such as tensile strength and impact resistance. The polyamide resin composition according to the present invention comprises, in 100% by mass of the polyamide resin composition, 35%-90% by mass of a polyamide resin (A1) having a constituent unit derived from a reaction product of pentamethylenediamine and an aliphatic dicarboxylic acid, 0%-5% by mass of polyamide 6 (A2), and 5%-60% by mass of a reinforcing filler (B) coated with a sizing agent including a polyurethane resin.
C08L 77/00 - Compositions contenant des polyamides obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
Provided is a multilayer polyimide film that is excellent in heat-resistance, low dielectric loss tangent, and dimensional stability. The multilayer polyimide film has: a layer of a heat-resistant polyimide; and a layer of a heat-bondable polyimide laminated on one surface or both surfaces thereof. The heat-resistant polyimide is obtained from: a tetracarboxylic acid component containing 75 mol% or more of 3,3',4,4'-biphenyltetracarboxylic acid dianhydride (s-BPDA) and 25 mol% or less of pyromellitic acid dianhydride (PMDA); and a diamine component containing 70-95 mol% of p-phenylenediamine and 5-30 mol% of 2,2'-dimethylbenzidine. The heat-bondable polyimide is obtained from: a tetracarboxylic acid component containing 10-60 mol% of the s-BPDA and 40-90 mol% of the PMDA; and a diamine component containing 50 mol% or more of 2,2-bis[4-(4-aminophenoxy)phenyl]propane.
B32B 27/34 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyamides
B32B 15/088 - Produits stratifiés composés essentiellement de métal comprenant un métal comme seul composant ou comme composant principal d'une couche adjacente à une autre couche d'une substance spécifique de résine synthétique comprenant des polyamides
H05K 1/03 - Emploi de matériaux pour réaliser le substrat
77.
TRANSITION METAL COMPOSITE OXIDE POWDER, ELECTRODE OBTAINED USING SAME, AND NON-AQUEOUS ELECTROLYTE POWER STORAGE DEVICE
Provided is a transition metal composite oxide powder which contains at least zinc and niobium, and which is characterized in that the molar ratio (MNb/MZn) of niobium relative to zinc is such that 8≤MNb/MZn≤40, and the D50 value of primary particles, which corresponds to a cumulative volume of 50% in a volume-based particle size distribution determined using a laser diffraction scattering method, is 0.25-2.8 μm.
H01G 11/24 - Électrodes caractérisées par les propriétés structurelles des matériaux composant les électrodes ou inclus dans les électrodes, p. ex. forme, surface ou porositéÉlectrodes caractérisées par les propriétés structurelles des poudres ou particules utilisées à cet effet
H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
H01M 4/485 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'oxydes ou d'hydroxydes mixtes pour insérer ou intercaler des métaux légers, p. ex. LiTi2O4 ou LiTi2OxFy
Provided is a polyimide precursor composition for producing a flexible electronic device substrate, the polyimide precursor composition giving a polyimide film that can quickly attenuate electric charges. This polyimide precursor composition includes a polyimide precursor and exhibits the following property: when a pair of electrodes are formed, at a distance d therebetween, on a 10 μm-thick polyimide film formed from the polyimide precursor to prepare a test sample, a direct voltage is applied between the pair of electrodes while the test sample is being irradiated with laser light, and subsequently the voltage is removed, then SHG light observed between the pair of electrodes rapidly attenuates.
B32B 17/10 - Produits stratifiés composés essentiellement d'une feuille de verre ou de fibres de verre, de scorie ou d'une substance similaire comprenant du verre comme seul composant ou comme composant principal d'une couche adjacente à une autre couche d'une substance spécifique de résine synthétique
B32B 27/34 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyamides
H05K 1/03 - Emploi de matériaux pour réaliser le substrat
79.
Polyimide binder precursor composition, and power storage device using same
A polyimide binder from which a high-capacity power storage device, which has a small irreversible capacity and a high initial charge/discharge efficiency and is lightweight, can be obtained. The polyimide binder precursor composition is a polyimide binder precursor composition for a power storage device electrode, and includes a reaction product of a tetracarboxylic acid component and a diamine component, and a solvent. The polyimide binder obtained from the polyimide binder precursor composition has an irreversible capacity of 1200 mAh/g or less.
H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides
H01G 11/28 - Électrodes caractérisées par leur structure, p. ex. multicouches, selon la porosité ou les caractéristiques de surface agencées ou disposées sur un collecteur de courantCouches ou phases entre les électrodes et les collecteurs de courant, p. ex. adhésifs
H01G 11/50 - Électrodes caractérisées par leur matériau spécialement adaptées aux condensateurs lithium-ion, p. ex. pour doper le lithium ou pour intercalation
H01G 11/86 - Procédés de fabrication de condensateurs hybrides ou EDL ou de leurs composants spécialement adaptés pour les électrodes
H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif
H01M 4/133 - Électrodes à base de matériau carboné, p. ex. composés d'intercalation du graphite ou CFx
H01M 4/587 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
80.
SILICON NITRIDE POWDER AND METHOD FOR PRODUCING SILICON NITRIDE SINTERED BODY
The main problem addressed by the present invention is to provide a crystalline silicon nitride powder capable of obtaining a silicon nitride sintered body having easy sinterability, sufficient mechanical strength characteristics, and excellent thermal conductivity. The present invention provides a silicon nitride powder characterized by containing primary particles of silicon nitride, having an amorphous layer comprising silicon oxide and/or silicon oxynitride on the surface of the primary particles, having an average thickness of the amorphous layer of 5.0 nm or less, having a coefficient of variation in the amorphous layer thickness represented by a specific formula (1) of 0.60 or less, and having a halogen content of 130 ppm or less. Also provided is a method for producing a silicon nitride sintered body, the method having a step for molding and sintering a sintering raw material containing the silicon nitride powder and a sintering aid.
To provide a more useful antitumor drug that is more advanced than a conventional antibody-drug conjugate. [Solution] An antibody multi-drugs conjugate represented by a following General Formula (I): [wherein the symbols have the meanings described in Description of the present application], or a pharmacologically acceptable salt thereof.
A61K 31/337 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à quatre chaînons, p. ex. taxol
A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
A61K 31/407 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des systèmes hétérocycliques, p. ex. kétorolac, physostigmine
A61K 31/4375 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. quinolizines, naphtyridines, berbérine, vincamine
A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
A61K 31/475 - QuinoléinesIsoquinoléines ayant un cycle indole, p. ex. yohimbine, réserpine, strychnine, vinblastine
A61K 31/537 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un oxygène comme hétéro-atomes d'un cycle, p. ex. 1,2-oxazines condensées en spiro ou formant une partie de systèmes cycliques pontés
A61K 31/5513 - 1,4-Benzodiazépines, p. ex. diazépam
A61K 31/675 - Composés du phosphore ayant l'azote comme hétéro-atome d'un cycle, p. ex. phosphate de pyridoxal
A61K 31/7034 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine
A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A resin recovery method according to the present invention is a method for recovering a resin from a composite including a layer (A) containing a non-hydrolyzable resin (a1) and a layer (B) containing a hydrolyzable resin (b1), wherein the resin recovery method includes a step (1) in which the composite and a subcritical fluid are brought into contact, the layer (A) and the layer (B) are decomposed and/or separated, and a solid resin (A) comprising a non-hydrolyzable resin (a2) and a solid resin (B) comprising a hydrolyzable resin (b2) are obtained. The non-hydrolyzable resin (a1) and the non-hydrolyzable resin (a2) are the same or differ only in molecular weight distribution, and the hydrolyzable resin (b1) and the hydrolyzable resin (b2) are the same or differ only in molecular weight distribution.
C08J 11/10 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation
The present invention provides a novel linker, a linker-payload, and an antibody-drug conjugate, as well as an antitumor drug. Specifically, the present invention provides an antibody-drug conjugate represented by the following general formula (I): A-(B-L-D)a (I) [wherein A is an antibody residue in which functional group(s) in antibody involved in binding to linker(s) is/are removed from an antibody which can target a tumor cell; B is a divalent group derived from said functional group in antibody; a is an integer of 1 to 10; D is an antitumor drug residue in which one hydrogen atom or one hydroxy group is removed from any position of an antitumor drug molecule or an analog thereof, or a derivative thereof; L is a linker which links B to D; and at least any one of D and L has one or more lactonyl group (s) as substituent(s) or protecting group (s) at any position(s)] or a pharmacologically acceptable salt thereof, or a hydrate thereof, and the like.
A61K 31/337 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à quatre chaînons, p. ex. taxol
A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
A61K 31/407 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des systèmes hétérocycliques, p. ex. kétorolac, physostigmine
A61K 31/4375 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. quinolizines, naphtyridines, berbérine, vincamine
A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
A61K 31/475 - QuinoléinesIsoquinoléines ayant un cycle indole, p. ex. yohimbine, réserpine, strychnine, vinblastine
A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine
A61K 31/537 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un oxygène comme hétéro-atomes d'un cycle, p. ex. 1,2-oxazines condensées en spiro ou formant une partie de systèmes cycliques pontés
A61K 31/5513 - 1,4-Benzodiazépines, p. ex. diazépam
A61K 31/5517 - 1,4-Benzodiazépines, p. ex. diazépam condensées avec des cycles à cinq chaînons ayant l'azote comme hétéro-atome d'un cycle, p. ex. imidazobenzodiazépines, triazolam
A61K 31/675 - Composés du phosphore ayant l'azote comme hétéro-atome d'un cycle, p. ex. phosphate de pyridoxal
A61K 31/7034 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine
A61K 31/7036 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine ayant au moins un groupe amino lié directement au carbocycle, p. ex. streptomycine, gentamycine, amikacine, validamycine, fortimicines
A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
A61K 38/14 - Peptides contenant des radicaux saccharideLeurs dérivés
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
C07K 16/30 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire provenant de cellules de tumeurs
Provided is a polyamide resin composition which exhibits good mechanical characteristics typified by tensile strength, good characteristics required of a sliding article, such as fatigue strength and abrasion resistance, and good molding properties typified by fluidity. This polyamide resin composition contains an aliphatic polyamide resin (A) and glass fibers coated with a sizing agent. With regard to all polyamide resins in the polyamide resin composition, the ratio of the peak area of a polyamide resin having a molecular weight of 30,000 or less is 22.00-30.00 area% and the ratio of the peak area of a polyamide resin having a molecular weight of 100,000 or more is 14.00-27.00 area%, each relative to the total area of peaks calculated in terms of standard poly(methyl methacrylate) using gel permeation chromatography. The molecular weight distribution (weight average molecular weight (Mw)/number average molecular weight (Mn)) of all polyamide resins in the polyamide resin composition is 4.00-8.50. The sizing agent contains a polyurethane resin and a copolymer having an acidic group.
C08L 77/00 - Compositions contenant des polyamides obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
85.
PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME
The present invention relates to the provision of a pharmaceutical composition useful in the treatment of Alport syndrome. The present invention provides a pharmaceutical composition useful in the treatment of Alport syndrome, comprising a compound represented by the following general formula (I) or (II) or a pharmaceutically acceptable salt thereof, wherein A is a C6-C10 aryl group or a heteroaryl group, wherein at least one hydrogen atom of the aryl group or the heteroaryl group is optionally replaced with a substituent selected from a predetermined group, R is a hydrogen atom or a C1-C6 alkyl group, R1 is a hydrogen atom or a halogen atom, and Y is a hydrogen atom, a fluorine atom or a hydroxy group.
The present invention relates to the provision of a pharmaceutical composition useful in the treatment of Alport syndrome. The present invention provides a pharmaceutical composition useful in the treatment of Alport syndrome, comprising a compound represented by the following general formula (I) or (II) or a pharmaceutically acceptable salt thereof, wherein A is a C6-C10 aryl group or a heteroaryl group, wherein at least one hydrogen atom of the aryl group or the heteroaryl group is optionally replaced with a substituent selected from a predetermined group, R is a hydrogen atom or a C1-C6 alkyl group, R1 is a hydrogen atom or a halogen atom, and Y is a hydrogen atom, a fluorine atom or a hydroxy group.
Disclosed is a polyolefin microporous membrane which has a polyethylene resin layer that contains a polyethylene resin and a polypropylene resin layer that contains a polypropylene resin, wherein: the content ratio of the polyethylene resin in the total mass of the polyolefin microporous membrane is 5 mass% to 45 mass%; the porosity of the polyolefin microporous membrane is 42% to 62%; the surface aperture ratio of the polypropylene resin layer is 5% to 30%; and the surface aperture ratio of the polyethylene resin layer is 5% to 20.6%.
B32B 5/32 - Produits stratifiés caractérisés par l'hétérogénéité ou la structure physique d'une des couches caractérisés par la présence de plusieurs couches qui comportent des fibres, filaments, grains ou poudre, ou qui sont sous forme de mousse ou essentiellement poreuses les deux couches étant sous forme de mousse ou essentiellement poreuses
B32B 27/32 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyoléfines
H01M 50/457 - Séparateurs, membranes ou diaphragmes caractérisés par le matériau ayant une structure en couches comprenant au moins trois couches
H01M 50/489 - Séparateurs, membranes, diaphragmes ou éléments d’espacement dans les cellules caractérisés par leurs propriétés physiques, p. ex. degré de gonflement, hydrophilicité ou propriétés pour court-circuiter
A polyimide film including a polyimide prepared by reacting a tetracarboxylic acid component with a diamine component containing 4,4″-diamino-p-terphenyl, wherein the polyimide film has a glass transition temperature of higher than 290° C., and has a coefficient of linear expansion in the temperature range of 50° C. to 200° C. of 10 ppm/K or less.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
17 - Produits en caoutchouc ou en matières plastiques; matières à calfeutrer et à isoler
Produits et services
Chemicals; carbon; cellulose; methane; cellulose derivatives
[chemicals]; plasticizers; dispersions of plastics;
non-metallic minerals; plastics [raw materials]; plastics,
unprocessed; synthetic resins, unprocessed; artificial
resins, unprocessed; polymer resins, unprocessed; conductive
resins, unprocessed; glue and adhesives for industrial
purposes; conductive adhesives; plant growth regulating
preparations; fertilizers; masterbatch consisting of
torrefied biomass derived from wood and resin; unprocessed
plastics in the form of pellets. Semi-finished plastic products; rubber [raw or semi-worked];
synthetic rubber; latex [rubber]; electrical insulating
materials; chemical fiber, not for textile use; inorganic
fiber, not for textile use; chemical fiber yarn and thread,
not for textile use; inorganic fiber yarn and thread, not
for textile use; plastic sheeting for agricultural purposes.
An emulsion composition according to the present invention contains a polyurethane resin (A), a curing agent (B), an acrylic resin (C), and an aqueous medium (D). The polyurethane resin (A) has a structure derived from a polycarbonate polyol (Aa), a structure derived from a polyisocyanate (Ab), a structure derived from an acidic-group-containing polyol (Ac), and a structure derived from a hydroxyl-group-containing polyamine (Ad). The acrylic resin (C) has a hydroxyl group. The emulsion composition according to the present invention can contribute to sustainable development goals (SDGs).
C08G 18/00 - Polymérisats d'isocyanates ou d'isothiocyanates
C08G 18/50 - Polyéthers contenant des hétéro-atomes autres que l'oxygène
C08G 18/62 - Polymères de composés contenant des liaisons doubles carbone-carbone
C08L 33/06 - Homopolymères ou copolymères des esters d'esters ne contenant que du carbone, de l'hydrogène et de l'oxygène, l'oxygène, faisant uniquement partie du radical carboxyle
C09D 7/63 - Adjuvants non macromoléculaires organiques
C09D 133/00 - Compositions de revêtement à base d'homopolymères ou de copolymères de composés possédant un ou plusieurs radicaux aliphatiques non saturés, chacun ne contenant qu'une seule liaison double carbone-carbone et l'un au moins étant terminé par un seul radical carboxyle, ou ses sels, anhydrides, esters, amides, imides ou nitrilesCompositions de revêtement à base de dérivés de tels polymères
A polyamide-based elastomer according to the present invention comprises a hard segment comprising a polyamide structure (A) and a constituent unit (D) derived from an iminodialkanoic acid compound (d) represented by general formula (I) and a soft segment comprising a polyether structure (B), wherein the constituent unit (D) is contained in an amount of 0-0.50 parts by mass, excluding 0 part by mass, per 100 parts by mass of the hard segment. (In general formula (I), R1and R2 each independently represent a C2-20 alkylene group.)
The present invention provides a method for cryopreserving cells, the method being characterized in that the cells are cryopreserved for 30 days or longer in a state where the cells are seeded onto a porous membrane without using liquid nitrogen. Also provided is a method for culturing cells, the method including a step for cryopreserving cells seeded onto a porous membrane for 30 days or longer without using liquid nitrogen. Further provided is a cryopreservation substrate which is formed from a porous film and is used for the cryopreservation of seeded cells for 30 days or longer.
A molded article obtained from the polyamide resin composition has improved mechanical properties including a tensile strength, a tensile modulus, a flexural strength, and a flexural modulus, and improved suppression of warpage. The polyamide resin composition of the present invention is a polyamide resin composition comprising an aliphatic polyamide resin (A) and a fibrous reinforcing filler (B), wherein the aliphatic polyamide resin (A) has a number average molecular weight of less than 22,000, and wherein the ratio of a median of the fiber length of the fibrous reinforcing filler (B) to an average of the fiber length of the fibrous reinforcing filler (B) is 0.50 to less than 0.90.
B29C 48/00 - Moulage par extrusion, c.-à-d. en exprimant la matière à mouler dans une matrice ou une filière qui lui donne la forme désiréeAppareils à cet effet
B29C 48/40 - Moyens pour plastifier ou homogénéiser la matière à mouler ou pour la forcer dans la filière ou la matrice utilisant des vis entourées par un fourreau coopérant, p. ex. des extrudeuses à vis simple utilisant au moins deux vis parallèles, p. ex. extrudeuses à vis doubles
B29K 77/00 - Utilisation de polyamides, p. ex. polyesteramides, comme matière de moulage
C08J 5/04 - Renforcement des composés macromoléculaires avec des matériaux fibreux en vrac ou en nappes
A polyimide which is a polycondensate of a monomer (A) comprising a tetracarboxylic acid dianhydride represented by the following general formula (1):
A polyimide which is a polycondensate of a monomer (A) comprising a tetracarboxylic acid dianhydride represented by the following general formula (1):
A polyimide which is a polycondensate of a monomer (A) comprising a tetracarboxylic acid dianhydride represented by the following general formula (1):
(In formula (1), R1s each independently represent a hydrogen atom etc., and R2s each independently represent a hydrogen atom etc.)
and a monomer (B) comprising a diamine compound, wherein
a content ratio of the monomer (A) is 100.2 moles to 105 moles relative to 100 moles of the monomer (B).
The present invention relates to a polyamide resin composition comprising, based on 100% by mass of the polyamide resin composition, (A) 55.0%-96.0% by mass of an aliphatic polyamide resin, (B) 1.0%-10.0% by mass of a cross-linking agent, and (C) 3.0%-28.0% by mass of glass fibers, wherein the aliphatic polyamide resin (A) is at least one selected from the group consisting of (A-1) polycondensation products of a diamine having 4-6 carbon atoms and a dicarboxylic acid having 8-13 carbon atoms, and (A-2) polycondensation products of a diamine having 8-13 carbon atoms and a dicarboxylic acid having 4-6 carbon atoms. The polyamide resin composition can contribute to the achievement of Goals 12, 13, 15, and the like of sustainable development goals (SDGs) from the viewpoints of reducing the amounts of resin components, metal components, or retrograded components thereof discharged due to abrasion, and enabling the use as a member having high reliability over a long period of time.
A graphite-copper composite material includes a copper layer and scaly graphite particles stacked via the copper layer. The graphite-copper composite material has a copper volume fraction of 3% to 30%. A thickness of a copper oxide layer at an interface between the copper layer and the scaly graphite particles is 100 nm at a maximum.
B22F 7/04 - Fabrication de couches composites, de pièces ou d'objets à base de poudres métalliques, par frittage avec ou sans compactage de couches successives avec une ou plusieurs couches non réalisées à partir de poudre, p. ex. à partir de tôles
H01L 23/373 - Refroidissement facilité par l'emploi de matériaux particuliers pour le dispositif
96.
COPOLYAMIDE RESIN, AND COMPOSITION, MOLDED ARTICLE, FILM AND MONOFILAMENT CONTAINING SAME
Provided are: a copolyamide resin which has a low enthalpy change ΔH when melted, exhibits excellent transparency due to having a low crystallinity, and which is obtained using a raw material derived from biomass; and a composition and a molded article such as a film or monofilament containing the copolyamide resin. The present invention can contribute to achieving Goal 12 and the like in Sustainable Development Goals (SDGs). The copolyamide resin contains: a constituent unit A derived from a product of a reaction between equimolar amounts of pentamethylenediamine and adipic acid; and a constituent unit B derived from a product of a reaction between equimolar amounts of pentamethylenediamine and sebacic acid. The constituent unit A/constituent unit B mass ratio is 85/15 to 15/85.
C08G 69/26 - Polyamides dérivés, soit des acides amino-carboxyliques, soit de polyamines et d'acides polycarboxyliques dérivés de polyamines et d'acides polycarboxyliques
97.
COPOLYMERIZED POLYAMIDE RESIN, AND COMPOSITION, MOLDED ARTICLE, FILM, AND MONOFILAMENT CONTAINING SAME
Provided is a copolymerized polyamide resin which has low water absorption and excellent abrasion resistance when made into molded articles, and in which a biomass-derived material is used. Also provided are a composition and molded articles such as a film and a monofilament containing the copolymerized polyamide resin. The present invention can contribute to the achievement of Goal 12, etc. of the Sustainable Development Goals (SDGs). The copolymerized polyamide resin contains: a structural unit A selected from the group consisting of a structural unit A1 derived from the product of an equimolar reaction between pentamethylenediamine and adipic acid, and a structural unit A2 derived from the product of an equimolar reaction between pentamethylenediamine and sebacic acid; and a structural unit B derived from at least one aminocarboxylic acid selected from among 10-aminodecanoic acid, 11-aminoundecanoic acid and 12-aminododecanoic acid, and/or at least one lactam selected from among decalactam, undecalactam and dodecalactam.
C08G 69/36 - Polyamides dérivés, soit des acides amino-carboxyliques, soit de polyamines et d'acides polycarboxyliques dérivés d'aminoacides, de polyamines et d'acides polycarboxyliques
This is to provide a polyamide resin composition that has good mechanical characteristics such as tensile characteristics, bending characteristics and impact resistance, and low water absorption.
This is to provide a polyamide resin composition that has good mechanical characteristics such as tensile characteristics, bending characteristics and impact resistance, and low water absorption.
The polyamide resin composition of the present invention comprises 55 to 78% by mass of an aliphatic polyamide resin (A), 20 to 35% by mass of glass fiber (B), 1 to 9% by mass of a crosslinking agent (C), 0.1 to 1.5% by mass of a heat-resistant agent (D) and 0 to 6% by mass of an inorganic filler other than glass fiber (E) in 100% by mass of the polyamide resin composition, and the aliphatic polyamide resin (A) has an average number of carbon atoms per one amide group of exceeding 6.
The present invention provides a method for industrially producing a highly pure aromatic nitrile compound and a highly pure aromatic carboxylic acid compound safely and highly efficiently at low costs. Compound (2) is subjected to Willgerodt reaction in the presence of an additive as necessary, and the obtained amide compound (3) is hydrolyzed and neutralized to give carboxylic acid compound (4). Carboxylic acid compound (4) is reacted with a halogenating agent in the presence of a catalyst as necessary in an organic solvent, and further reacted with an amidating agent, and the obtained amide compound (5) or (6) is reacted with a dehydrating agent to give nitrile compound (1). Alternatively, carboxylic acid compound (4) is reacted with a halogenating agent and a compound represented by the formula R6SO2R7 in the presence of a catalyst as necessary in an organic solvent to give nitrile compound (1). Np is a naphthyl group optionally having substituent(s), R5 is an alkylene group having 1-3 carbon atoms, and other symbols are as described in the DESCRIPTION.
The present invention provides a method for industrially producing a highly pure aromatic nitrile compound and a highly pure aromatic carboxylic acid compound safely and highly efficiently at low costs. Compound (2) is subjected to Willgerodt reaction in the presence of an additive as necessary, and the obtained amide compound (3) is hydrolyzed and neutralized to give carboxylic acid compound (4). Carboxylic acid compound (4) is reacted with a halogenating agent in the presence of a catalyst as necessary in an organic solvent, and further reacted with an amidating agent, and the obtained amide compound (5) or (6) is reacted with a dehydrating agent to give nitrile compound (1). Alternatively, carboxylic acid compound (4) is reacted with a halogenating agent and a compound represented by the formula R6SO2R7 in the presence of a catalyst as necessary in an organic solvent to give nitrile compound (1). Np is a naphthyl group optionally having substituent(s), R5 is an alkylene group having 1-3 carbon atoms, and other symbols are as described in the DESCRIPTION.
C07C 253/20 - Préparation de nitriles d'acides carboxyliques par déshydratation d'amides d'acides carboxyliques
C07C 51/06 - Préparation d'acides carboxyliques, de leurs sels, halogénures ou anhydrides à partir d'amides d'acides carboxyliques
C07C 57/38 - Composés non saturés comportant des groupes carboxyle liés à des atomes de carbone acycliques contenant des cycles aromatiques à six chaînons polycycliques
C07C 255/33 - Nitriles d'acides carboxyliques ayant des groupes cyano liés à des atomes de carbone acycliques ayant des groupes cyano liés à des atomes de carbone acycliques d'un squelette carboné contenant au moins un cycle aromatique à six chaînons avec des groupes cyano reliés au cycle aromatique à six chaînons ou au système cyclique condensé contenant ce cycle, par l'intermédiaire de chaînes carbonées saturées
Provided is a polyamide resin composition containing an aliphatic polyamide resin and a polyolefin exhibiting reactivity with a terminal group of the polyamide resin, wherein: the aliphatic polyamide resin has a portion derived from a linear or branched hydrocarbon compound at a proportion of 80 mol% or more in all monomer units; and, in the aliphatic polyamide resin, the ratio of the high molecular weight component to the low molecular weight component is within a specific range in the molecular weight distribution curve of the polymethyl methacrylate equivalent. According to this resin composition, a resin composition having excellent moldability and high hydrolysis resistance is provided.
C08L 77/00 - Compositions contenant des polyamides obtenus par des réactions créant une liaison amide carboxylique dans la chaîne principaleCompositions contenant des dérivés de tels polymères
C08L 23/26 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carboneCompositions contenant des dérivés de tels polymères modifiées par post-traitement chimique
F16L 11/04 - Manches, c.-à-d. tuyaux flexibles en caoutchouc ou en matériaux plastiques flexibles
