The present invention relates to an improved kit for preparing injectable carmustine solutions, methods of preparing and administering such solutions, and methods of treatment with such solutions. The kit includes a product vial containing lyophilised carmustine and a diluent vial containing an ethanol-free non-aqueous diluent. Reconstitution of the lyophilised carmustine in the ethanol-free non-aqueous diluent results in a carmustine solution with improved solubility and stability.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceuticals for the treatment of erectile dysfunction and sexual dysfunctions and disorders, and for the maintenance of sexual health, for use in the treatment and prevention of incontinence, for treatment of prostate and urinary tract diseases and disorders, for treatment of cardiovascular or endothelial disease, disorders or dysfunction, for treatment of neurodegenerative diseases, and for memory enhancement Medical information services, namely, providing information relating to the treatment of erectile dysfunction and sexual dysfunctions and disorders, and the maintenance of sexual health
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle counseling and consultancy for medical purposes; providing a website featuring information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle counseling and consultancy for medical purposes.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical preparations for the treatment of obesity, to facilitate weight loss and weight control, to suppress appetite and lower the threshold for satiety. Providing information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle counseling and consultancy for medical purposes; providing a website featuring information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle counseling and consultancy for medical purposes.
5.
METHODS OF REGULATING ACCESS TO QSYMIA TO MITIGATE POTENTIAL DRUG-ASSOCIATED RISKS
The present invention provides methods for dispensing or distributing a drug, particularly a potentially teratogenic drug, to a patient while minimizing the occurrence of an adverse side effect. In particular, the present invention provides methods for dispensing or distributing a drug containing topiramate to a patient in need of weight loss to minimize the occurrence of potential birth defects associated with the drug. Methods for providing training to prescribers on the potential risks associated with particular drugs are also disclosed.
G16H 20/13 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients delivrés par des distributeurs
G09B 19/00 - Enseignement non couvert par d'autres groupes principaux de la présente sous-classe
G09B 23/28 - Modèles à usage scientifique, médical ou mathématique, p. ex. dispositif en vraie grandeur pour la démonstration pour la médecine
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
G16H 40/00 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux
6.
ORALLY DISINTEGRATING DOSAGE FORM FOR ADMINISTRATION OF AVANAFIL, AND ASSOCIATED METHODS OF MANUFACTURE AND USE
Formulations are provided for the oral administration of avanafil, a Type V phosphodiesterase inhibitor (“PDE V inhibitor”), and analogs thereof. The formulations are orally disintegrating tablets (ODTs) that rapidly dissolve or disintegrate in the oral cavity. The tablets contain an absorption enhancing composition that increases the duodenal absorption of the active agent, following transfer from the low pH environment of the stomach to the more basic pH of the duodenum. Methods for administering the active agent using the dosage forms are provided. The invention also encompasses a method of selecting components and compositions to incorporate in the formulations which will facilitate increased absorption of the active agent in the duodenum and thus serve as “absorption enhancing compositions” herein. Also provided are methods for manufacturing orally disintegrating tablets to optimize the physical properties of the dosage forms, particularly hardness and disintegration time.
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing a website featuring information and advice in the fields of exocrine pancreatic insufficiency, the pancreas, health, healthcare, nutrition, and lifestyle wellness; Providing information and advice in the fields of exocrine pancreatic insufficiency, the pancreas, health, healthcare, nutrition, and lifestyle wellness
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle wellness; Providing a website featuring information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle wellness
05 - Produits pharmaceutiques, vétérinaires et hygièniques
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical preparations for the treatment of obesity, to facilitate weight loss and weight control, to suppress appetite and lower the threshold for satiety Providing information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle wellness; Providing a website featuring information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle wellness
10.
ORALLY ADMINISTRABLE FORMULATIONS FOR THE CONTROLLED RELEASE OF A PHARMACOLOGICALLY ACTIVE AGENT
Drug tablets that include a controlled release layer of a moisture-sensitive active agent are prepared with a lipidic matrix forming excipient, a water-soluble, channel forming excipient and a filler, each being non-hygroscopic. The tablets are formed in a process where the components are blended in the absence of moisture and in particulate form.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
The present invention provides compositions and methods for the treatment of pulmonary hypertension using combination therapy. The combination therapy comprises a compound that increases BMPR2 signaling (BMPR2 activator) in combination with at least one other agent for the treatment of pulmonary hypertension. In certain aspects, the BMPR2 activator can be tacrolimus or a pharmaceutically acceptable solvate, salt, or prodrug thereof.
A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
A61K 31/4025 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil non condensés et contenant d'autres hétérocycles, p. ex. cromakalim
A61K 31/422 - Oxazoles non condensés et contenant d'autres hétérocycles
A61K 31/497 - Pyrazines non condensées contenant d'autres hétérocycles
A61K 31/4985 - Pyrazines ou pipérazines condensées en ortho ou en péri avec des systèmes hétérocycliques
A61K 31/505 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
A61K 31/53 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec trois azote comme seuls hétéro-atomes d'un cycle, p. ex. chlorazanil, mélamine
A61K 31/5575 - Eicosanoïdes, p. ex. leucotriènes ayant un cycle cyclopentane, p. ex. prostaglandine E2, prostaglandine F2-alpha
A61K 31/5585 - Eicosanoïdes, p. ex. leucotriènes ayant des hétérocycles contenant l'oxygène comme seul hétéro-atome du cycle, p. ex. thromboxanes ayant des cycles à cinq chaînons contenant l'oxygène comme seul hétéro-atome du cycle, p. ex. prostacycline
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
12.
METHODS OF PREVENTING PROGRESSION TO TYPE 2 DIABETES MELITUS
The present invention provides compositions and methods for delaying or preventing progression to type 2 diabetes mellitus in individuals with prediabetes and metabolic syndrome.
A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
05 - Produits pharmaceutiques, vétérinaires et hygièniques
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
pharmaceuticals; pharmaceutical preparations for the treatment of obesity, to facilitate weight loss and weight control, to suppress appetite and lower the threshold for satiety. Providing information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle wellness via a website.
14.
TREATMENT OF SLEEP APNEA WITH A COMBINATION OF A CARBONIC ANHYDRASE INHIBITOR AND AN ALDOSTERONE ANTAGONIST
This invention relates generally to methods and pharmaceutical formulations useful in treating patients suffering from sleep apnea, including obstructive sleep apnea syndrome (OSAS). Treatment is effected by administering a carbonic anhydrase inhibitor to the patient in combination with an aldosterone antagonist. Formulations containing a therapeutically effective amount of a carbonic anhydrase inhibitor and a therapeutically effective amount of an aldosterone antagonist are provided as well.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/423 - Oxazoles condensés avec des carbocycles
A61K 31/575 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne d'au moins trois atomes de carbone, p. ex. cholane, cholestane, ergostérol, sitostérol
A61K 31/585 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes contenant des hétérocycles, p. ex. danazol, stanozolol, pancuronium ou digitogénine contenant des cycles lactone, p. ex. oxandrolone, bufaline
15.
METHODS OF REGULATING ACCESS TO QSYMIA TO MITIGATE POTENTIAL DRUG-ASSOCIATED RISKS
The present invention provides methods for dispensing or distributing a drug, particularly a potentially teratogenic drug, to a patient while minimizing the occurrence of an adverse side effect. In particular, the present invention provides methods for dispensing or distributing a drug containing topiramate to a patient in need of weight loss to minimize the occurrence of potential birth defects associated with the drug. Methods for providing training to prescribers on the potential risks associated with particular drugs are also disclosed.
G16H 20/13 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients delivrés par des distributeurs
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
G09B 23/28 - Modèles à usage scientifique, médical ou mathématique, p. ex. dispositif en vraie grandeur pour la démonstration pour la médecine
G09B 19/00 - Enseignement non couvert par d'autres groupes principaux de la présente sous-classe
G16H 40/00 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux
16.
ESCALATING DOSING REGIMEN FOR EFFECTING WEIGHT LOSS AND TREATING OBESITY
The present invention is drawn to novel topiramate compositions as well as methods for effecting weight loss, e.g., in the treatment of obesity and related conditions, including conditions associated with and/or caused by obesity per se. The present invention features an escalating dosing regimen adapted for the administration of topiramate and optionally a sympathomimetic agent such as phentermine or bupropion, in the treatment of obesity and related conditions.
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
17.
LOW DOSE TOPIRAMATE/PHENTERMINE COMPOSITION AND METHODS OF USE THEREOF
A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in the range of 2 mg to 8 mg, in combination with a daily dose of topiramate selected to prevent the loss of effectiveness of phentermine alone. Methods for treating obesity, conditions associated with obesity, and other indications are also provided, as are compositions and dosage forms containing low doses of phentermine and topiramate, e.g., 3.75 mg phentermine and 23 mg topiramate.
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 9/28 - DragéesPilules ou comprimés avec revêtements
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Pharmaceutical services, namely, processing online prescription orders for pharmaceutical products central fill pharmacies; online retail store services featuring dietary supplements, nutritional supplements, and vitamins
(2) Providing information and advice in the fields of exocrine pancreatic insufficiency; providing a website featuring information and advice in the fields of exocrine pancreatic insufficiency.
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical services, namely, processing online prescription orders for pharmaceutical products central fill pharmacies; online retail store services featuring dietary supplements, nutritional supplements, and vitamins Providing information and advice in the fields of exocrine pancreatic insufficiency; providing a website featuring information and advice in the fields of exocrine pancreatic insufficiency
The present invention provides compositions and methods for the treatment or prevention of pulmonary hypertension comprising administering an ascomycin, or a pharmaceutically acceptable salt, solvate, analog, or prodrug thereof to the patient with pulmonary hypertension. Described herein are liquid formulations which deliver an ascomycin. The liquid formulation can be placed in a soft gelatin capsule.
A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
A61K 31/395 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61K 31/4353 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques
22.
ORALLY DISINTEGRATING DOSAGE FORM FOR ADMINISTRATION OF AVANAFIL, AND ASSOCIATED METHODS OF MANUFACTURE AND USE
Formulations are provided for the oral administration of avanafil, a Type V phosphodiesterase inhibitor (“PDE V inhibitor”), and analogs thereof. The formulations are orally disintegrating tablets (ODTs) that rapidly dissolve or disintegrate in the oral cavity. The tablets contain an absorption enhancing composition that increases the duodenal absorption of the active agent, following transfer from the low pH environment of the stomach to the more basic pH of the duodenum. Methods for administering the active agent using the dosage forms are provided. The invention also encompasses a method of selecting components and compositions to incorporate in the formulations which will facilitate increased absorption of the active agent in the duodenum and thus serve as “absorption enhancing compositions” herein. Also provided are methods for manufacturing orally disintegrating tablets to optimize the physical properties of the dosage forms, particularly hardness and disintegration time.
The present invention provides compositions and methods for the treatment or prevention of pulmonary hypertension comprising administering an ascomycin, or a pharmaceutically acceptable salt, solvate, analog, or prodrug thereof to the patient with pulmonary hypertension.
A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
24.
METHODS OF TREATING OBESITY IN RESPONDER AND NON-RESPONDER POPULATIONS
The disclosed embodiments relate to, dosing regimens for the administration of topiramate, optionally in combination with one or more sympathomimetic agents such as phentermine. The dosing regimens can, for example, limit the exposure of subjects to topiramate, identify subjects who are unlikely to obtain a benefit from treatment with escalating dosages of topiramate (with or without the sympathomimetic agent, such as phentermine), or both, thereby reducing or eliminating harmful or intolerable side effects in subjects who are unlikely to respond to treatment and maximizing the therapeutic benefits from treatment in subjects who do respond.
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing information and advice in the fields of exocrine pancreatic insufficiency, health, healthcare, nutrition, weight management, weight gain, diet planning, and lifestyle wellness; Providing a website featuring information and advice in the fields of exocrine pancreatic insufficiency, health, healthcare, nutrition, weight management, weight gain, diet planning, and lifestyle wellness
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing information and advice in the fields of exocrine pancreatic insufficiency; Providing a website featuring information and advice in the fields of exocrine pancreatic insufficiency
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical services, namely, processing online prescription orders for pharmaceutical products central fill pharmacies; online retail store services featuring dietary supplements and nutritional supplements Providing information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle wellness; Providing a website featuring information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle wellness
Pharmaceutical services, namely, processing online prescription orders for pharmaceutical products central fill pharmacies; online retail store services featuring dietary supplements, nutritional supplements, and vitamins
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical services, namely, processing online prescription orders for pharmaceutical products central fill pharmacies; online retail store services featuring dietary supplements and nutritional supplements Providing information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle wellness; Providing a website featuring information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle wellness
Pharmaceutical services, namely, processing online prescription orders for pharmaceutical products central fill pharmacies; online retail store services featuring dietary supplements, nutritional supplements, and vitamins
Pharmaceutical services, namely, processing online prescription orders for pharmaceutical products central fill pharmacies; online retail store services featuring dietary supplements, nutritional supplements, and vitamins
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical services, namely, processing online prescription orders for pharmaceutical products central fill pharmacies; online retail store services featuring dietary supplements and nutritional supplements Providing a website featuring information and advice in the fields of health, healthcare, diet, weight management, weight loss, weight management treatment, diet planning, and lifestyle wellness
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing a website featuring information and advice in the fields of exocrine pancreatic insufficiency, health, healthcare, nutrition, weight management, weight gain, diet planning, and lifestyle wellness
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing information and advice in the fields of health,
healthcare, diet, weight management, weight gain, weight
loss, weight management treatment, diet planning, and
lifestyle wellness via a website.
09 - Appareils et instruments scientifiques et électriques
35 - Publicité; Affaires commerciales
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Downloadable software in the nature of a mobile application
for monitoring, receiving, processing, transmitting,
displaying and analyzing medical patient data for use in
patient management, care coordination and clinical decision
support; downloadable software for use with medical patient
monitoring apparatus and equipment, for monitoring,
receiving, processing, transmitting, displaying, and
analyzing data and images; downloadable software application
for providing electronic communication of healthcare and
health-related questions, information and advice between
users and healthcare professionals and the scheduling of
telemedicine appointment times with healthcare
professionals; downloadable software in the nature of a
mobile application for patient access to physicians and
health care professionals, counseling, medicinal, health
care, nutrition and pharmaceutical advice, pharmaceutical
prescriptions, and telemedicine; downloadable computer
software for controlling and managing patient medical
information. Online retail store services featuring medical devices and
apparatus; online retail store services featuring medical
patient monitoring apparatus and equipment, and electronic
patient monitoring devices; online retail store services
featuring pulse oximeters, blood pressure diagnostic
devices, scales, and spirometers. Telemedicine services; telehealth services, namely,
providing healthcare and health-related information via
telecommunication technologies; providing medical
information via an internet website for medical
professionals and patients featuring medical information
from remote locations via electronic patient monitoring
devices that feed information to the web site for purposes
of monitoring and diagnosing medical conditions.
The present invention relates to an improved kit for preparing injectable carmustine solutions, methods of preparing and administering such solutions, and methods of treatment with such solutions. The kit includes a product vial containing lyophilised carmustine and a diluent vial containing an ethanol-free non-aqueous diluent. Reconstitution of the lyophilised carmustine in the ethanol-free non-aqueous diluent results in a carmustine solution with improved solubility and stability.
09 - Appareils et instruments scientifiques et électriques
35 - Publicité; Affaires commerciales
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Downloadable software in the nature of a mobile application for monitoring, receiving, processing, transmitting, displaying and analyzing medical patient data for use in patient management, care coordination and clinical decision support; downloadable software for use with medical patient monitoring apparatus and equipment, namely, smartwatches, blood pressure monitors, weight scales, pulse oximeters, cardiac monitors, electrocardiographs, glucose monitors, for monitoring, receiving, processing, transmitting, displaying, and analyzing data and images relating to the user's vital signs, nutrition and medication tracking; downloadable software application for providing electronic communication of healthcare and health related questions, information and advice between users and healthcare professionals and the scheduling of telemedicine appointment times with healthcare professionals; downloadable software in the nature of a mobile application for patient access to physicians and health care professionals, counseling, medicinal, health care, nutrition and pharmaceutical advice, pharmaceutical prescriptions, and telemedicine; downloadable computer software for controlling and managing patient medical information. (1) Online retail store services featuring medical devices and apparatus, namely, smartwatches, blood pressure monitors, weight scales, pulse oximeters, cardiac monitors, electrocardiographs, glucose monitors; online retail store services featuring medical patient monitoring apparatus and equipment, and electronic patient monitoring devices; online retail store services featuring pulse oximeters, blood pressure diagnostic devices, scales, and spirometers.
(2) Telemedicine services; telehealth services, namely, providing healthcare and health-related information via telecommunication technologies; providing medical information via an internet website for medical professionals and patients featuring medical information from remote locations via electronic patient monitoring devices that feed information to the web site for purposes of monitoring and diagnosing medical conditions.
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Providing information and advice in the fields of health and healthcare, namely, the treatment of health conditions relating to obesity, diet, weight management, weight gain, weight loss, weight management treatment, diet planning, and lifestyle wellness via a website.
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing a website featuring information and advice in the fields of health, healthcare, diet, weight management, weight gain, weight loss, weight management treatment, diet planning, and lifestyle wellness
09 - Appareils et instruments scientifiques et électriques
35 - Publicité; Affaires commerciales
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Downloadable software in the nature of a mobile application for monitoring, receiving, processing, transmitting, displaying and analyzing medical patient data for use in patient management, care coordination and clinical decision support; Downloadable software for use with medical patient monitoring apparatus and equipment, for monitoring, receiving, processing, transmitting, displaying, and analyzing data and images; Downloadable software application for providing electronic communication of healthcare and health-related questions, information and advice between users and healthcare professionals and the scheduling of telemedicine appointment times with healthcare professionals; Downloadable software in the nature of a mobile application for patient access to physicians and health care professionals, counseling, medicinal, health care, nutrition and pharmaceutical advice, pharmaceutical prescriptions, and telemedicine; Downloadable computer software for controlling and managing patient medical information online retail store services featuring medical devices and apparatus; online retail store services featuring medical patient monitoring apparatus and equipment, and electronic patient monitoring devices; online retail store services featuring pulse oximeters, blood pressure diagnostic devices, scales, and spirometers Telemedicine services; Telehealth services, namely, providing healthcare and health-related information via telecommunication technologies; providing an internet website for medical professionals and patients featuring medical information from remote locations via electronic patient monitoring devices that feed information to the web site for purposes of monitoring and diagnosing medical conditions
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for the treatment of the exocrine system, and exocrine deficiencies, disorders and diseases; pharmaceutical preparations for the treatment of the digestive system; pharmaceutical preparations for the treatment of pancreatic diseases and disorders, enzyme disorders and deficiencies, and gastrointestinal diseases and disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of the exocrine system, and exocrine deficiencies, disorders and diseases, namely, for the treatment of exocrine pancreatic insufficiency; Pharmaceutical preparations, namely, enzymes, for the treatment of the exocrine system, and exocrine deficiencies, disorders and diseases; pharmaceutical preparations for the treatment of the digestive system; pharmaceutical preparations for the treatment of pancreatic diseases and disorders, enzyme disorders and deficiencies, and gastrointestinal diseases and disorders
43.
Methods of preventing progression to type 2 diabetes mellitus
The present invention provides compositions and methods for delaying or preventing progression to type 2 diabetes mellitus in individuals with prediabetes and metabolic syndrome.
A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
44.
Orally disintegrating dosage form for administration of avanafil, and associated methods of manufacture and use
Formulations are provided for the oral administration of avanafil, a Type V phosphodiesterase inhibitor (“PDE V inhibitor”), and analogs thereof. The formulations are orally disintegrating tablets (ODTs) that rapidly dissolve or disintegrate in the oral cavity. The tablets contain an absorption enhancing composition that increases the duodenal absorption of the active agent, following transfer from the low pH environment of the stomach to the more basic pH of the duodenum. Methods for administering the active agent using the dosage forms are provided. The invention also encompasses a method of selecting components and compositions to incorporate in the formulations which will facilitate increased absorption of the active agent in the duodenum and thus serve as “absorption enhancing compositions” herein. Also provided are methods for manufacturing orally disintegrating tablets to optimize the physical properties of the dosage forms, particularly hardness and disintegration time.
The present invention provides compositions and methods for delaying or preventing progression to type 2 diabetes mellitus in individuals with prediabetes and metabolic syndrome.
A61K 31/70 - Hydrates de carboneSucresLeurs dérivés
A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
46.
Low dose topiramate/phentermine composition and methods of use thereof
A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in the range of 2 mg to 8 mg, in combination with a daily dose of topiramate selected to prevent the loss of effectiveness of phentermine alone. Methods for treating obesity, conditions associated with obesity, and other indications are also provided, as are compositions and dosage forms containing low doses of phentermine and topiramate, e.g., 3.75 mg phentermine and 23 mg topiramate.
A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
A61K 9/28 - DragéesPilules ou comprimés avec revêtements
47.
Escalating dosing regimen for effecting weight loss and treating obesity
The present invention is drawn to novel topiramate compositions as well as methods for effecting weight loss, e.g., in the treatment of obesity and related conditions, including conditions associated with and/or caused by obesity per se. The present invention features an escalating dosing regimen adapted for the administration of topiramate and optionally a sympathomimetic agent such as phentermine or bupropion, in the treatment of obesity and related conditions.
A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
A61K 31/135 - Amines, p. ex. amantadine ayant des cycles aromatiques, p. ex. méthadone
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
The present invention is drawn to novel topiramate compositions as well as methods for effecting weight loss, e.g., in the treatment of obesity and related conditions, including conditions associated with and/or caused by obesity per se. The present invention features an escalating dosing regimen adapted for the administration of topiramate and optionally a sympathomimetic agent such as phentermine or bupropion, in the treatment of obesity and related conditions.
A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 31/135 - Amines, p. ex. amantadine ayant des cycles aromatiques, p. ex. méthadone
49.
Low dose topiramate/phentermine composition and methods of use thereof
A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in the range of 2 mg to 8 mg, in combination with a daily dose of topiramate selected to prevent the loss of effectiveness of phentermine alone. Methods for treating obesity, conditions associated with obesity, and other indications are also provided, as are compositions and dosage forms containing low doses of phentermine and topiramate, e.g., 3.75 mg phentermine and 23 mg topiramate.
A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
A61K 9/28 - DragéesPilules ou comprimés avec revêtements
A61K 31/357 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant plusieurs atomes d'oxygène dans le même cycle, p. ex. éthers en couronne, guanadrel
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceuticals for the treatment of erectile dysfunction and sexual dysfunctions and disorders, and for the maintenance of sexual health, for use in the treatment and prevention of incontinence, for treatment of prostate and urinary tract diseases and disorders, for treatment of cardiovascular or endothelial disease, disorders or dysfunction, for treatment of neurodegenerative diseases, and for memory enhancement.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for the treatment of obesity, to
facilitate weight loss and weight control, to suppress
appetite and lower the threshold for satiety.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of obesity, to facilitate weight loss and weight control, to suppress appetite and lower the threshold for satiety
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for the treatment of obesity, to faciliate weight loss and weight control, to suppress appetite and lower the threshold for satiety.
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Providing a website featuring information and advice in the fields of health, healthcare, diet, weight loss, diet planning and lifestyle wellness, and featuring online tools for management of diet, dieting and weight loss programs
(2) Providing a website featuring information and advice in the fields of health, healthcare, diet, weight loss, diet planning and lifestyle wellness.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical for the treatment of erectile dysfunction and sexual dysfunctions and disorders, and for the maintenance of sexual health, for use in the treatment and prevention of incontinence, for treatment of prostate and urinary tract diseases and disorders, for treatment of cardiovascular or endothelial diseases, disorders or dysfunction, for treatment of neurodegenerative diseases, and for memory enhancement.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceuticals for the treatment of erectile dysfunction and sexual dysfunctions and disorders, and for the maintenance of sexual health, for use in the treatment and prevention of incontinence, for treatment of prostate and urinary tract diseases and disorders, for treatment of cardiovascular and endothelial disease, disorders and dysfunction, for treatment of neurodegenerative diseases, namely, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, fronto-temporal dementia with Parkinson's features, progressive supranuclear palsies, essential dyskinesias and dementia, and for memory enhancement.
58.
Treatment of pulmonary hypertension with carbonic anhydrase inhibitors
This disclosure relates generally to methods and pharmaceutical compositions useful in treating pulmonary hypertension. In one embodiment, for example, the disclosure provides a method for treating pulmonary hypertension comprising administering a therapeutically effective dose of a carbonic anhydrase inhibitor to a patient in need of treatment. The disclosure finds utility in the fields of medicine and pharmacology.
A61K 31/53 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec trois azote comme seuls hétéro-atomes d'un cycle, p. ex. chlorazanil, mélamine
A61K 31/407 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des systèmes hétérocycliques, p. ex. kétorolac, physostigmine
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine
A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for the treatment of obesity, to facilitate weight loss and weight control, to suppress appetite and lower the threshold for satiety
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for the treatment of obesity, to facilitate weight loss and weight control, to suppress appetite and lower the threshold for satiety, for treatment of metabolic disorders and for treatment of diabetes, cardiovascular disorders and cardiovascular diseases in humans
63.
Low dose topiramate/phentermine composition and methods of use thereof
A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in the range of 2 mg to 8 mg, in combination with a daily dose of topiramate selected to prevent the loss of effectiveness of phentermine alone. Methods for treating obesity, conditions associated with obesity, and other indications are also provided, as are compositions and dosage forms containing low doses of phentermine and topiramate, e.g., 3.75 mg phentermine and 23 mg topiramate.
The present invention is drawn to novel topiramate compositions as well as methods for effecting weight loss, e.g., in the treatment of obesity and related conditions, including conditions associated with and/or caused by obesity per se. The present invention features an escalating dosing regimen adapted for the administration of topiramate and optionally a sympathomimetic agent such as phentermine or bupropion, in the treatment of obesity and related conditions.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceuticals for human use, namely, pharmaceuticals for the treatment of erectile dysfunction and sexual dysfunctions and disorders in males and females, for the maintenance of sexual health, urinary incontinence, for the treatment of obesity, to facilitate weight loss and weight control, to suppress appetite and lower the threshold for satiety, cardiovascular disorders and cardiovascular diseases in humans, and neurodegenerative diseases.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceuticals for human use, namely, pharmaceuticals [ for the treatment of erectile dysfunction and sexual dysfunctions and disorders in males and females, for the maintenance of sexual health, urinary incontinence, ] for the treatment of obesity, to facilitate weight loss and weight control, to suppress appetite and lower the threshold for satiety, cardiovascular disorders and cardiovascular diseases in humans [, and neurodegenerative diseases ]
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceuticals for human use, namely, pharmaceuticals [ for the treatment of erectile dysfunction and sexual dysfunctions and disorders in males and females, for the maintenance of sexual health, urinary incontinence, ] for the treatment of obesity, to facilitate weight loss and weight control, to suppress appetite and lower the threshold for satiety, cardiovascular disorders and cardiovascular diseases in humans, [ and neurodegenerative diseases ]
69.
Treatment of pulmonary hypertension with carbonic anhydrase inhibitors
This disclosure relates generally to methods and pharmaceutical compositions useful in treating pulmonary hypertension. In one embodiment, for example, the disclosure provides a method for treating pulmonary hypertension comprising administering a therapeutically effective dose of a carbonic anhydrase inhibitor to a patient in need of treatment. The disclosure finds utility in the fields of medicine and pharmacology.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical, veterinary and sanitary preparations; dietetic substances adapted for medical use, food for babies; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides.
The present invention is drawn to novel topiramate compositions as well as methods for effecting weight loss. The present invention features an escalating dosing regimen adapted for the administration of topiramate and phentermine.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A unit dosage form for weight loss for oral administration to a subject having a body mass index of at least 25 kg/m2 comprising a combination of: an immediate release phentermine formulation containing a unit dosage of phentermine in the range of 2 mg to 8 mg; and a controlled release topiramate formulation containing a unit dosage of topiramate in the range of 15 mg to 50 mg, wherein the dosage of phentermine in mg/day is about 16% of the dosage of topiramate in mg/day.
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
