Abrégé

Disclosed is an apparatus for decoding a linear code or a binary code by using a quantum circuit, the apparatus comprising a quantum circuit for decoding a linear code executed on a quantum computer, wherein the quantum circuit comprises: a generator matrix operation module, into which a received message vector is inputted and which converts the received message vector into a codeword; and a Hamming weight calculation module, which calculates the Hamming distance d between the converted codeword and the inputted vector to estimate the presence and number of errors.

Classes IPC  ?

• G06N 10/70 - Correction, détection ou prévention d’erreur quantique, p. ex. codes de surface ou distillation d’état magique
• G06N 10/60 - Algorithmes quantiques, p. ex. fondés sur l'optimisation quantique ou les transformées quantiques de Fourier ou de Hadamard
• G06N 10/20 - Modèles d’informatique quantique, p. ex. circuits quantiques ou ordinateurs quantiques universels
• G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p. ex. couplage ou commande de qubit
• B82Y 10/00 - Nanotechnologie pour le traitement, le stockage ou la transmission d’informations, p. ex. calcul quantique ou logique à un électron

Abrégé

The present disclosure relates to a 3D map providing system, and includes a user terminal that communicates through a wireless communication network, and a server that provides a 3D map to the user terminal through a dedicated application and generates the 3D map by combining spatial information and location information for each area. According to the present disclosure, there is an effect of improving readability and visibility by providing a 3D map.

Classes IPC  ?

• G06T 17/05 - Modèles géographiques
• G06Q 50/26 - Services gouvernementaux ou services publics

Abrégé

The present invention relates to an anode active material for a lithium secondary battery, a preparation method therefor, and a lithium secondary battery comprising the anode active material, the anode active material comprising a plurality of spherical natural graphite particles, wherein the spherical natural graphite particles are structured such that flaky natural graphite fragment particles are coagulated and assembled in a cabbage-like shape or randomly, phosphorus (P) atoms form C-O-P or C-P-O bonds on the edge planes of all or at least some of the flaky natural graphite fragment particles constituting the surface or inside of each of the spherical natural graphite particles, the spherical natural graphite particles have a protruding/recessed surface morphology including a structurally-protruding portion protruding from the particle surface and a structurally-recessed portion recessed from the particle surface, the percentage of the number of particles having a circularity of 0.95 or less is 66% or higher, and the tap density is 1.17 g/cm3 or greater.

Classes IPC  ?

• H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
• H01M 4/583 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx
• H01M 10/052 - Accumulateurs au lithium
• C01B 32/21 - Post-traitement
• H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif

Abrégé

According to an aspect of the present invention, there is provided a system for generating random numbers based on blood samples including a sample loading module configured to supply a preset blood sample, a light irradiation module configured to irradiate the blood sample provided by the sample loading module with light, the blood sample moved to a pre-designated region of interest (ROI) being irradiated with light, an image generation module configured to acquire an original speckle image by capturing an image of the blood sample located in the region of interest in a preset method using the light irradiation module, and a random number generation module configured to generate random numbers by processing the original speckle image generated from the image generation module in a preset method.

Classes IPC  ?

• G06F 7/58 - Générateurs de nombres aléatoires ou pseudo-aléatoires
• G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS

Abrégé

The present invention relates to an LFMP-based positive electrode active material for a lithium secondary battery, provided with excellent capacity and lifetime characteristics, and a secondary battery including the same, and specifically, relates to an LFMP-based positive electrode active material for a lithium secondary battery, provided with excellent capacity and long life characteristics due to the composition of the LFMP-based positive electrode active material and structural characteristics of a positive electrode including the same, and a lithium secondary battery including the same.

Classes IPC  ?

• H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
• H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif
• H01M 4/04 - Procédés de fabrication en général
• H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
• H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
• H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium

Abrégé

The present invention relates to an apparatus for separating and sorting waste LED modules, and provides an apparatus in which a separating apparatus, which separates LED packages and PCBs from LED modules, and a sorting apparatus, which sorts the separated LED packages from the PCBs, are connected, and LED modules are injected through a sample inlet of the separating apparatus and LED packages are separated from the PCBs by using high-temperature hot air current in a cylindrical body, and then the separated LED packages and PCBs are moved to the sorting apparatus and can be sorted by a sieve. To achieve the above purpose, the apparatus for separating and sorting waste LED packages, according to the present invention, comprises: a separating apparatus which moves a plurality of waste LED modules injected into a chamber to a rotational moving portion provided therein, and rises the temperature in the chamber to separate and discharge LED packages and PCBs; and a sorting apparatus which is located at the lower end of the separating apparatus and is provided with a sieve so that the LED packages can be sorted via the sieve from the LED packages and PCBs separately discharged from the separating apparatus.

Classes IPC  ?

• B02C 19/18 - Utilisation d'effets physiques auxiliaires aidant la désagrégation, p. ex. ultrasons, irradiation
• B02C 23/16 - Séparation ou triage de matériaux, associé au broyage ou à la désagrégation au moyen d'un séparateur délimitant la fin de la zone de broyage ou de désagrégation, p. ex. au moyen d'un tamis empêchant la sortie des matériaux hors dimension
• B02C 17/16 - Appareils comportant des agitateurs placés dans une cuve fixe entraînant le contenu en mouvement
• B07B 1/28 - Tamis mobiles non prévus ailleurs, p. ex. à oscillations, à mouvement alternatif, à balancement, à basculement ou à vacillement

Abrégé

The present invention relates to an apparatus for generating a generative adversarial network (GAN)-based electrocardiogram reconstruction model, the apparatus comprising: an input unit for receiving a single-lead electrocardiogram; a generator for reconstructing a 12-lead electrocardiogram on the basis of the single-lead electrocardiogram; and a discriminator that uses one of a first input value, which is a combination of the 12-lead electrocardiogram and the single-lead electrocardiogram, or a second input value, which is a combination of an actual 12-lead electrocardiogram (ground-truth) and the single-lead electrocardiogram, as an input value, and determines whether the input value is the reconstructed 12-lead electrocardiogram or the actual 12-lead electrocardiogram. According to the present invention, a multi-lead electrocardiogram that more accurately reflects the characteristics of an actual electrocardiogram can be reconstructed from a single lead electrocardiogram.

Classes IPC  ?

• A61B 5/327 - Génération de signaux ECG artificiels à partir de signaux mesurés, p. ex. pour pallier l’absence d’électrodes
• A61B 5/349 - Détection de paramètres spécifiques du cycle de l'électrocardiogramme
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G06N 3/088 - Apprentissage non supervisé, p. ex. apprentissage compétitif
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux

Abrégé

The present invention relates to a beamforming method and apparatus in RIS element grouping. The beamforming method performed by a wireless device including one or more reconfigurable intelligent surface (RIS) groups comprises the steps of: acquiring channel estimation values; and determining reflection coefficients for the RIS groups on the basis of the channel estimation values, wherein a reflection coefficient for any one of the RIS groups is different from a reflection coefficient for another one of the RIS groups.

Classes IPC  ?

• H04B 7/04 - Systèmes de diversitéSystèmes à plusieurs antennes, c.-à-d. émission ou réception utilisant plusieurs antennes utilisant plusieurs antennes indépendantes espacées
• H04B 7/06 - Systèmes de diversitéSystèmes à plusieurs antennes, c.-à-d. émission ou réception utilisant plusieurs antennes utilisant plusieurs antennes indépendantes espacées à la station d'émission
• H01Q 15/00 - Dispositifs pour la réflexion, la réfraction, la diffraction ou la polarisation des ondes rayonnées par une antenne, p. ex. dispositifs quasi optiques
• H04L 25/02 - Systèmes à bande de base Détails

Abrégé

The present invention relates to use of CXCL11 for treating pulmonary fibrosis by inducing the repolarization of M2 macrophages. Specifically, a fibrosis treatment effect was confirmed through the injection of M0, M1 and M2 conditioned media (CM) by using a bleomycin-induced pulmonary fibrosis animal model, and a reduction in fibrosis markers such as collagen and a change in the M1/M2 ratio close to a normal group were confirmed in the lungs of mice into which the M1 macrophage CM was injected. Also, the fibrosis treatment effect was confirmed through the intravenous injection of human recombinant CXCL11 by using a bleomycin-induced pulmonary fibrosis animal model, and a reduction in fibrosis markers such as collagen and a change in the M1/M2 ratio close to a normal group were confirmed in the lungs of mice to which CXCL11 was administered. That is, the present invention aims to induce the repolarization of M2 macrophages through CXCL11 in the process of developing pulmonary fibrosis, and thus CXCL11 is presented as a potential target factor for the treatment of pulmonary fibrosis.

Classes IPC  ?

• A61K 38/19 - CytokinesLymphokinesInterférons
• A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes

Abrégé

The present invention relates to a method for specifically degrading a KRAS mutant (G12V) by treating a cell line expressing the KRAS mutant (G12V) with a complex of a RAS binder binding specifically to the KRAS mutant (G12V) and an E3 ligase NEDD4HECT, and a composition used in the method. When the method developed in the present invention is applied to a cell line expressing a wild-type KRAS, the wild-type KRAS is not degraded. In a KRAS mutant (G12V) cell line, it was confirmed that while a protein level is reduced, ERK activity is inhibited and proliferation and penetration of cancer cells related to the KRAS mutant (G12V) are inhibited.

Classes IPC  ?

• C12N 9/10 - Transférases (2.)
• C12N 9/14 - Hydrolases (3.)

Abrégé

The present invention relates to specific degradation of cancer suppressor protein p53 and oncoprotein KRAS, and, more specifically, to a method in which a cell line expressing p53 and KRAS is treated with a complex of E3 ligase subunit SPOP167-374 and Rbx1delC and binders that specifically bind to p53 and KRAS, so that respective proteins are specifically degraded; and a composition used in the method. It has been identified that the method developed in the present invention allows p53 expressed in the nucleus to be degraded if a cell line is treated with Nb139_ SPOP167-374, and allows KRAS expressed in the cell membrane to be degraded if a cell line is treated with KRAS binder_ Rbx1delC.

Classes IPC  ?

• C12N 9/10 - Transférases (2.)
• C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères

Abrégé

The present invention relates to synthetic mRNA comprising an apoptin-derived peptide coding sequence, and use thereof. The synthetic mRNA consisting of a base sequence of SEQ ID NO: 1 has an excellent effect of inducing apoptosis of cancer cells, and thus can be effectively used in the field of cancer therapeutic agent development.

Classes IPC  ?

• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
• A61P 35/00 - Agents anticancéreux
• A23L 33/13 - Acides nucléiques ou leurs dérivés
• A61K 38/00 - Préparations médicinales contenant des peptides

Abrégé

The present invention relates to synthetic mRNA comprising an apoptin protein coding sequence and a use thereof. The synthetic mRNA composed of a base sequence of SEQ ID NO: 1 has excellent effect in inducing apoptosis of cancer cells, and thus can be usefully employed in the field of developing cancer therapeutic agents.

Classes IPC  ?

• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
• A61P 35/00 - Agents anticancéreux
• A23L 33/13 - Acides nucléiques ou leurs dérivés
• A61K 38/00 - Préparations médicinales contenant des peptides

Abrégé

The present invention relates to a method for recovering magnesium from sediment generated in an electrolytic chlorine generation system using seawater or brackish water, the method comprising the steps of: eluting magnesium by using sulfuric acid in magnesium hydroxide, which is sediment generated in an electrolytic chlorine generation system using seawater and brackish water; precipitating magnesium sulfate by adding an organic solvent to a magnesium-eluted solution; and after the precipitation of the magnesium sulfate, separating the organic solvent and sulfuric acid by using a vacuum evaporation method, and reusing the organic solvent.

Classes IPC  ?

• C22B 26/22 - Obtention du magnésium
• C01F 5/40 - Sulfates de magnésium
• C22B 3/44 - Traitement ou purification de solutions, p. ex. de solutions obtenues par lixiviation par des procédés chimiques
• C22B 7/00 - Mise en œuvre de matériaux autres que des minerais, p. ex. des rognures, pour produire des métaux non ferreux ou leurs composés

Abrégé

A method for training a medical image classification model using a multi-filter auto-augmentation includes training, by using a training dataset including raw medical image data, a plurality of first neural network models to classify medical image data into a predetermined class, in which the plurality of first neural network models have different neural network model structures, auto-augmenting the raw medical image data to generate medical image augmentation data, filtering data of the medical image augmentation data, which has a class probability of belonging to a class classified by each of the plurality of first neural network models, equal to or greater than a predetermined criterion, as effective augmentation data, and training, by using a training dataset including the effective augmentation data and the raw medical image data, a second neural network model to classify medical image data into a predetermined class.

Classes IPC  ?

• G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”
• G06N 3/045 - Combinaisons de réseaux
• G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
• G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition

Abrégé

A new hemp cultivar Pinkpepper (Cannabis sativa L. cv. Pinkpepper) plant deposited under Accession Number KACC 88008BP has a higher content of cannabinoids than the seed and pollen parents. The new hemp cultivar Pinkpepper (Cannabis sativa L. cv. Pinkpepper) plant can be advantageously used as hemp for medical purpose, or obtaining hemp seeds or fibers.

Classes IPC  ?

• A01H 6/28 - Cannabaceae, p. ex. cannabis
• A01H 5/02 - Fleurs
• A61K 8/9789 - Magnoliopsida [dicotylédones]
• A61K 36/185 - Magnoliopsida (dicotylédones)
• C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
• C12Q 1/6895 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les plantes, les champignons ou les algues

Abrégé

A new hemp cultivar Cherry king (Cannabis sativa L. cv. Cherry king) plant is obtained through open pollination using Cherry wine genetic resource as a seed parent, which is deposited under Accession Number KACC 88007BP and which has a higher content of cannabinoids than the seed parent, as well as a use thereof.

Classes IPC  ?

• A01H 6/28 - Cannabaceae, p. ex. cannabis
• A01H 5/02 - Fleurs
• A61K 8/9789 - Magnoliopsida [dicotylédones]
• A61K 36/185 - Magnoliopsida (dicotylédones)
• A61P 31/04 - Agents antibactériens

Abrégé

Disclosed herein is a method of operating a single slope analog-to-digital converter (ADC), which includes receiving an input signal from a sensor or a ramp signal from a ramp generator according to a state of a switch and sampling the received input or ramp signal, comparing, by a comparator, whether the sampled ramp signal is present in a predetermined input range in a state in which the ramp generator maintains an off state and outputting the comparison result, generating, by a logic part, a flag signal indicating a high or low according to the comparison result by the comparator and providing the flag signal to the ramp generator, and sampling, by the ramp generator, a reference voltage of the comparator according to the flag signal based on an off or on state.

Classes IPC  ?

• H03M 1/56 - Comparaison du signal d'entrée avec une rampe linéaire
• H03M 1/12 - Convertisseurs analogiques/numériques
• H03M 1/06 - Compensation ou prévention continue de l'influence indésirable de paramètres physiques
• H03M 1/08 - Compensation ou prévention continue de l'influence indésirable de paramètres physiques du bruit

Abrégé

The present invention relates to a vegan potato serum preparation method using a potato emulsion mixture during preparation, and a vegan potato serum prepared using the method. The vegan potato serum has excellent texture and formulation stability, and the potato emulsion mixture included in the serum exhibits antioxidant activity, and thus the present invention is expected to be effectively used in cosmetic compositions for antioxidant effects.

Classes IPC  ?

• A61K 8/9789 - Magnoliopsida [dicotylédones]
• A61K 8/92 - Huiles, graisses ou ciresLeurs dérivés, p. ex. produits d'hydrogénation
• A61K 8/73 - Polysaccharides
• A61K 8/19 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés inorganiques
• A61K 8/67 - Vitamines
• A61K 8/34 - Alcools
• A61K 8/37 - Esters d'acides carboxyliques
• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation

Abrégé

The present disclosure relates to a nanostructure for detecting viruses including an amphipathic polymer, and a diagnostic platform using the same, wherein the nanostructure is capable of specifically detecting viruses through silica-based nanoparticles with excellent stability and high dispersion and a biocompatible amphipathic polymer, such that it is possible to develop a diagnostic platform with high sensitivity through binding and agglomeration of the nanostructure and viruses and enable rapid and accurate diagnosis of a target virus.

Classes IPC  ?

• G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• G01N 33/549 - Support organique avec un antigène ou un anticorps emprisonnés dans le support
• G01N 33/552 - Verre ou silice

Abrégé

The present invention relates to a nanostructure containing polymersomes and quantum dots, and a virus detection method using the nanostructure, which has been confirmed to have high sensitivity and high specificity compared to conventional virus detection methods and accurately detect viruses even in patients exhibiting low sensitivity, and thus can be useful as a virus detection method.

Classes IPC  ?

• G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
• G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus

Abrégé

Disclosed is an apparatus for producing reduced silicon nanopowder, comprising: a housing having an inlet port on its top and an outlet port on its bottom; a motor installed in the housing; an annular raw material container installed inside the housing with raw material powder including silica and carbon being loaded and provided with an outer surface spaced apart from an inner surface of the housing, the raw material container rotating by receiving rotational force from the motor; and a laser beam generator for generating laser beams irradiated to the raw material powder of the raw material container through the inlet port. It is possible to load a large amount of raw material powder and thus produce more silicon nanopowder in a continuous process.

Classes IPC  ?

• C01B 33/025 - Préparation par réduction de silice ou d'un matériau contenant de la silice avec du carbone ou un matériau carboné solide, c.-à-d. procédé carbothermique
• B23K 26/00 - Travail par rayon laser, p. ex. soudage, découpage ou perçage

Abrégé

A method for producing CAR-M1 macrophages expressing a chimeric antigen receptor in vitro and in vivo includes using a conjugate of a non-viral gene delivery system and a chimeric antigen receptor gene. The CAR-M1 macrophages are produced in vivo by delivering genes encoding a chimeric antigen receptor and IFN-γ, specifically to macrophages in the body, and thus does not require culturing and preparing an in-vitro cellular therapeutic agent, thus reducing the manufacturing costs of therapeutic agents. The CAR-M1 macrophages are a safer therapy since a non-viral vector is used, as compared to the production of CAR-M1 macrophages by gene delivery using a viral vector, and are a novel therapeutic candidate having the advantage of high anticancer efficiency for solid cancers, due to CAR-M1 macrophages in which intrinsic properties of macrophages infiltrating solid cancers and cancer cell phagocytosis are improved.

Classes IPC  ?

• A61K 35/15 - Cellules de la lignée des myéloïdes, p. ex. granulocytes, basophiles, éosinophiles, neutrophiles, leucocytes, monocytes, macrophages ou mastocytesCellules précurseurs myéloïdesCellules présentatrices d’antigène, p. ex. cellules dendritiques
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61P 35/00 - Agents anticancéreux
• C07K 14/555 - Interférons [IFN]
• C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
• C12N 5/0786 - MonocytesMacrophages
• C12N 9/12 - Transférases (2.) transférant des groupes contenant du phosphore, p. ex. kinases (2.7)
• C12N 11/08 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique le support étant un polymère synthétique

Abrégé

The present invention relates to a method for digitally formalizing medical examination readouts, the method classifying the types of medical examination readouts, and extracting characters in the classified medical examination readouts, wherein the characters are extracted by separating character detection and character recognition, and thus the accuracy of digitizing medical examination readouts can be increased to 98.6%.

Classes IPC  ?

• G06V 30/148 - Découpage de zones de caractères
• G06V 30/16 - Prétraitement de l’image
• G06V 30/146 - Alignement ou centrage du capteur d’image ou du champ d’image
• G06V 30/19 - Reconnaissance utilisant des moyens électroniques
• G06V 30/418 - Appariement de documents, p. ex. d’images de documents
• G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p. ex. leur création ou leur transmission

Abrégé

The present invention relates to a method for cultivating seed potatoes with enhanced yield, the method comprising the step of growing potato plants with silicon dioxide treatment in an aeroponic system, seed potatoes cultivated by the method, and a method for increasing the yield of seed potatoes.

Classes IPC  ?

• A01G 31/00 - Culture hors-sol, p. ex. hydroponie
• A01G 22/25 - Légumes-racines, p. ex. pommes de terre, ignames, betterave ou wasabi
• A01G 7/06 - Traitement des arbres ou des plantes en cours de croissance, p. ex. pour prévenir la décomposition du bois, pour teinter les fleurs ou le bois, pour prolonger la vie des plantes
• A01N 59/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des éléments ou des composés inorganiques
• A01N 43/12 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome des cycles à cinq chaînons condensés avec un carbocycle
• A01N 25/06 - Aérosols

Abrégé

The present invention relates to antagonist microorganisms for inhibiting fire blight and a composition for preventing or inhibiting fire blight comprising the same as an active ingredient, and provides antagonist microorganisms exhibiting excellent antagonistic ability against a causative bacterium, Erwinia amylovora. According to the present invention, the antagonist microorganisms for inhibiting fire blight isolated in Korea are provided to replace a biological control agent for inhibiting fire blight, which requires enormous costs depending on imports.

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• A01N 63/22 - Bacillus
• A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges

Abrégé

The present invention relates to 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-ons and derivatives thereof, a method for producing the same, and a composition for prevention, improvement or treatment of neurodegenerative disease containing the same. Specifically, 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-ons and derivatives thereof, which are novel compounds of the present invention, can be used as an excellent composition for prevention, improvement or treatment of neurodegenerative disease.

Classes IPC  ?

• C07D 403/10 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
• C07D 233/96 - Composés hétérocycliques contenant des cycles diazole-1, 3 ou diazole-1, 3 hydrogéné, non condensés avec d'autres cycles comportant trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques
• C07D 401/06 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

The present invention relates to a cell culture device, a cell culture system comprising same and a manufacturing method therefor. Particularly, the present invention provides a cell culture device and a manufacturing method therefor, the device comprising a substrate and a silicone layer applied to at least one surface of the substrate. In addition, provided are a cell culture system and a cell culture method using same, the system comprising, inside a chamber, a culture solution together with a cell culture device having surfaces coated with a silicone layer.

Classes IPC  ?

• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires

Abrégé

The present invention relates to a method for recovering magnesium from sediment generated in an electrolytic chlorine generation system using seawater or brackish water, the method comprising the steps of: eluting magnesium by using sulfuric acid in magnesium hydroxide, which is sediment generated in an electrolytic chlorine generation system using seawater and brackish water; precipitating magnesium sulfate by adding an organic solvent to a magnesium-eluted solution; and after the precipitation of the magnesium sulfate, separating the organic solvent and sulfuric acid by using a vacuum evaporation method, and reusing the organic solvent.

Classes IPC  ?

• C22B 26/22 - Obtention du magnésium
• C22B 3/08 - Acide sulfurique
• C22B 3/04 - Extraction de composés métalliques par voie humide à partir de minerais ou de concentrés par lixiviation
• C22B 3/16 - Extraction de composés métalliques par voie humide à partir de minerais ou de concentrés par lixiviation dans des solutions organiques

Abrégé

The present invention relates to a crop concentration preparation method, a crop concentration prepared by the method, and processed food using the crop concentration, the crop concentration preparation method comprising the steps of: (1) preparing a crop syrup by saccharifying crop by adding amylase; (2) inactivating the enzymes by heating the crop syrup prepared in step (1); and (3) concentrating the crop syrup having inactivated enzymes from step (2).

Classes IPC  ?

• A23L 2/38 - Autres boissons non alcoolisées
• A23L 19/10 - Produits à base de fruits ou de légumesLeur préparation ou leur traitement de tubercules ou d'autres racines contenant de l'amidon
• A23L 29/00 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement
• A23L 3/44 - Lyophilisation
• A23P 30/20 - Extrusion
• A23C 11/00 - Succédanés du lait, p. ex. compositions pour remplacer le lait dans le café au lait
• A23L 29/269 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des agents gélifiants ou épaississants d'origine microbienne, p. ex. xanthane ou dextrane

Abrégé

Provided is a method of controlling local release of target compounds by patterning a hydrogel carrying a bone morphogenetic protein or anticancer drug as the target compounds onto an electrospun nanoporous membrane. The hydrogel is capable of controlling local release of the bone morphogenetic protein or anticancer drug as a carrier of the bone morphogenetic protein or anticancer. And the electrospun nanoporous membrane performs a basic function of the membrane of preventing infiltration of connective tissue. Thus, there is an advantage in that the hydrogel patterned nanoporous membrane can facilitate generation of controlled bone in a local region and degradation of cancer in a local region.

Classes IPC  ?

• A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
• A61K 9/28 - DragéesPilules ou comprimés avec revêtements
• A61K 9/70 - Bases pour bande, feuille ou filament
• A61K 9/20 - Pilules, pastilles ou comprimés

Abrégé

The present invention relates to a method for mass production of a high content of cannabidiol (CBD) from Cannabis sativa L. Considering that, by decarboxylating a raw material as it is without extracting C. sativa L., a high content of CBD can be produced by reducing CBD loss, optimal temperature and time conditions in a decarboxylation step are established, and after the decarboxylation, isolation conditions in an isolation step of the CBD are also established, to thereby have an advantage of enabling mass production by increasing the yield of CBD. Therefore, the CBD produced by the method for mass production of the present invention is expected to be usefully applied as various medicinal materials

Classes IPC  ?

• C07C 37/70 - SéparationPurificationStabilisationEmploi d'additifs par traitement physique
• C07C 39/23 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle aromatique à six chaînons polycycliques contenant des cycles aromatiques à six chaînons et d'autres cycles avec une insaturation autre que celle des cycles aromatiques

Abrégé

The present invention relates to an antibody-binding recombinant fusion protein and an antibody-drug conjugate using same. The recombinant fusion protein comprises a secretory peptide, an albumin binding domain, and an antibody binding domain, and the antibody-drug conjugate can be prepared without chemical binding. Due to including the albumin binding domain, the fusion protein can be comprehensively applied to an albumin-based nanocarrier containing abraxane, and thus can be utilized as an ADC platform technology that can be applied to albumin nanoparticles and the like for delivering various drugs.

Classes IPC  ?

• C07K 16/32 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des produits de traduction des oncogènes
• C07K 14/00 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
• A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc

Abrégé

The present invention relates to a recombinant protein for immune cell surface modification and a use thereof. The recombinant protein comprises a secretory peptide, an IgG kappa chain, a membrane targeting signal peptide, an ED domain, and a transmembrane domain and thus is easily introduced into a cell membrane, and is easily introduced into a cell membrane of an immune cell when mixed with the immune cell, thereby enabling modification of the surface of the immune cell, and various antibodies may be bound to the recombinant protein, thereby enabling improved target specificity and immunocompetence of the immune cell, and, on the basis of confirming that the recombinant protein is introduced into HEK293 cells, H9c2 cells, and NK-92 cells, the recombinant protein of the present invention is provided for the use of cell modification.

Classes IPC  ?

• C07K 14/31 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries provenant de Micrococcaceae (F) provenant de Staphylococcus (G)
• C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
• C12N 5/0783 - Cellules TCellules NKProgéniteurs de cellules T ou NK
• A61K 35/17 - LymphocytesLymphocytes BLymphocytes TCellules tueuses naturellesLymphocytes activés par un interféron ou une cytokine
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique

Abrégé

The present invention relates to: a method for producing CAR-M1 macrophages that express a chimeric antigen receptor, in vitro and in vivo, the method comprising a step of using a conjugate of a non-viral gene delivery system and a chimeric antigen receptor gene; CAR-M1 macrophages produced by the method; and use of the cells. The CAR-M1 macrophages of the present invention are produced in vivo by delivering genes encoding a chimeric antigen receptor and IFN―γ, specifically to macrophages in the body, and thus does not require steps of culturing and preparing an in-vitro cellular therapeutic agent, thus reducing the manufacturing costs of therapeutic agents. In addition, the CAR-M1 macrophages are a safer therapy since a non-viral vector is used, as compared to the production of CAR-M1 macrophages by gene delivery using a viral vector, and are a novel therapeutic candidate having the advantage of high anticancer efficiency for solid cancers, due to CAR-M1 macrophages in which intrinsic properties of macrophages infiltrating solid cancers and cancer cell phagocytosis are improved.

Classes IPC  ?

• C12N 5/0786 - MonocytesMacrophages
• C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
• C12N 9/12 - Transférases (2.) transférant des groupes contenant du phosphore, p. ex. kinases (2.7)
• C12N 11/08 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique le support étant un polymère synthétique
• A61K 35/15 - Cellules de la lignée des myéloïdes, p. ex. granulocytes, basophiles, éosinophiles, neutrophiles, leucocytes, monocytes, macrophages ou mastocytesCellules précurseurs myéloïdesCellules présentatrices d’antigène, p. ex. cellules dendritiques
• A61P 35/00 - Agents anticancéreux
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• G01N 33/533 - Production de composés immunochimiques marqués avec un marqueur fluorescent

Abrégé

The present invention relates to a multivalent vaccine composition for prevention of porcine mycoplasma and porcine circovirus infections and an infection prevention method using same. The multivalent vaccine composition according to the present invention exhibits a reciprocally supplemental effect on immune responses in pigs used as experimental animals and target animals and does not allow for interference between antigens. When inoculated into pigs, the vaccine composition induces high serological levels of antibody titers and neutralizing antibody titers and produces a high level of IFN-γ for Mhp or PCV2 sensitization in PBMC. Thus, the vaccine composition can find advantageous applications for preventing porcine mycoplasma and porcine circovirus infections.

Classes IPC  ?

• A61K 39/295 - Antigènes viraux polyvalentsMélanges d'antigènes viraux et bactériens
• A61K 39/02 - Antigènes bactériens
• A61K 39/12 - Antigènes viraux
• A61P 31/04 - Agents antibactériens
• A61P 31/12 - Antiviraux
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

The present invention relates to a non-contact portable tonometry system and tonometry method using a difference in infrared intensity. A nozzle module receives compressed air from a compressed air supply source and sprays the same through an air spray port to a cornea of a subject, thus to cause corneal deformation. An infrared ray sensor is disposed in the nozzle module to emit infrared rays to the cornea and measure an amount of light reflected from the cornea. A controller converts the amount of light measured by the infrared ray sensor before and after the deformation of corneal into intraocular pressure.

Classes IPC  ?

• A61B 3/16 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la pression intraoculaire, p. ex. tonomètres
• G01J 1/08 - Agencements des sources lumineuses spécialement adaptées à la photométrie

Abrégé

The present invention relates to a polymer conjugate-based composite for virus detection, the composite for virus detection having a characteristic of the light absorption spectrum changing when bound to a virus, and by means of such a change in the light absorption spectrum, the presence of a virus can be checked, and the virus can be quantified by numerically expressing the change in absorption spectrum.

Classes IPC  ?

• G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
• G01N 33/545 - Résine synthétique
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• G01N 21/31 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique

Abrégé

A screening method, described in the present specification, for targeting an epigenetic regulation mechanism of PHF6 causing the acetylation of H2BK12 and the ubiquitination of H2BK120, which are two independently known histone modifications involved in transcriptional regulation, to operate as a single functional unit may be useful for developing a therapeutic agent for a disease caused by an abnormality of the PHF6 gene.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

The present invention relates to a complex for regulating the activity of a cell activity-regulating material with disease cell-specific miRNA and a complex for disease-specific genetic manipulation in which the complex is applied to a CRISPR/Cas system.

Classes IPC  ?

• C12N 9/22 - Ribonucléases
• A61K 38/00 - Préparations médicinales contenant des peptides
• A61P 35/00 - Agents anticancéreux

Abrégé

Provided is an electronic device including a communication module, a memory, and at least one processor operatively connected to the communication module and the memory, and the memory stores instructions configured to, when executed, enable the at least one processor to: receive a first sentence via the communication module; identify a first newly coined word included in the first sentence; obtain a second sentence by identifying a first alternative word corresponding to the first newly coined word, and replacing the first newly coined word in the first sentence with the first alternative word; obtain a third sentence by correcting a grammatical error in the second sentence based on the first alternative word occurring the grammatical error when replacing the first newly coined word; and transmit the third sentence to an external device via the communication module. Other embodiments can be made.

Classes IPC  ?

• G06F 40/166 - Édition, p. ex. insertion ou suppression
• G06F 40/253 - Analyse grammaticaleCorrigé du style
• G06F 40/279 - Reconnaissance d’entités textuelles
• G06F 40/30 - Analyse sémantique
• G06N 20/00 - Apprentissage automatique

Abrégé

Disclosed is a detachable device for repeatedly measuring textural characteristics of food. To this end, the present invention includes: a fixing unit having a probe guide member having, at a center thereof, a predetermined guide hole, having therein a predetermined space, and extending downward; a cylindrical probe configured to move upward and downward while surrounding the probe guide member and having multiple holes formed in a lower surface thereof so that a part of food is extracted in accordance with a degree of compression at the time of compressing the food; a food sample cup positioned below the cylindrical probe and having therein a space in which the food is placed; and multiple position fixing guides positioned between the fixing unit and the food sample cup.

Classes IPC  ?

• G01N 3/28 - Recherche de la ductilité, p. ex. de l'aptitude des métaux en feuilles à l'emboutissage profond ou au filage
• G01N 3/08 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique par application d'efforts permanents de traction ou de compression
• G01N 3/02 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique Parties constitutives
• G01N 33/02 - Nourriture

Abrégé

According to various embodiments, an electronic device comprises a communication module, a memory, and at least one processor operably connected to the communication module and the memory, wherein the memory can store instructions which, when executed, enable the at least one processor to receive a first sentence via the communication module, identify a first neologism present in the first sentence, identify a first alternative word corresponding to the first neologism to obtain a second sentence by replacing the first neologism with the first alternative word in the first sentence, obtain a third sentence by correcting a grammatical error in the second sentence, on the basis of the first alternative word that causes the grammatical error when the first neologism is replaced, and transmit the third sentence to an external device via the communication module, and other embodiments are also feasible.

Classes IPC  ?

• G06F 40/237 - Outils lexicaux
• G06F 40/205 - Analyse syntaxique
• G06F 40/30 - Analyse sémantique
• G06F 16/33 - Requêtes
• G06F 16/332 - Formulation de requêtes
• G06F 16/36 - Création d’outils sémantiques, p. ex. ontologie ou thésaurus
• G10L 15/26 - Systèmes de synthèse de texte à partir de la parole
• G06N 20/00 - Apprentissage automatique
• G06F 3/041 - Numériseurs, p. ex. pour des écrans ou des pavés tactiles, caractérisés par les moyens de transduction

Abrégé

The present invention relates to a press-heating gas grafting hydrophobization apparatus, and a hot water-resistant paper and an oil-absorbing paper manufactured using the press-heating gas grafting hydrophobization apparatus. In the press-heating gas grafting hydrophobization apparatus according to the present invention, since a non-air-permeable dryer belt is provided surrounding and pressing a drying roller to prevent dissipation from a base material of a fatty acid chloride vaporized by the drying roller, the press-heating gas grafting hydrophobization apparatus has an advantage of improving efficiency of a gas grafting reaction. Therefore, by using the press-heating gas grafting hydrophobization apparatus according to the present invention, the reaction amount of fatty acid chloride per unit area can be remarkably improved.

Classes IPC  ?

• D21H 23/56 - Rouleaux
• D21H 17/36 - Alcools polyalcényliquesÉthers polyalcényliquesEsters polyalcényliques
• D21H 21/16 - Agents de collage ou hydrophobes
• D21H 25/06 - Traitement physique, p. ex. chauffage ou irradiation du papier imprégné ou couché
• D21H 27/00 - Papier particulier non prévu ailleurs, p. ex. obtenu par des procédés multi-étapes
• D21H 23/70 - Procédés multi-étapesAppareils pour ajouter au papier une ou plusieurs substances par portions ou de différentes manières, non couverts par un seul autre groupe du présent groupe principal

Abrégé

The present invention relates to a vaccine composition for preventing hand, foot, and mouth disease, comprising an immunologic adjuvant. Specifically, the present invention is characterized by significantly increasing protection against the infection of viruses causing hand, foot, and mouth disease by using GLA-SE as an immunologic adjuvant of the hand, foot, and mouth disease vaccine. The vaccine composition for hand, foot, and mouth disease, comprising GLA-SE of the present invention, when used, significantly increases protection against viral infections, and thus enables effective prevention of hand, foot, and mouth disease.

Classes IPC  ?

• A61K 39/125 - Picornaviridae, p. ex. calicivirus
• A61K 39/135 - Virus de la fièvre aphteuse
• A61K 39/295 - Antigènes viraux polyvalentsMélanges d'antigènes viraux et bactériens
• A61P 31/14 - Antiviraux pour le traitement des virus ARN
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

The present invention relates to a peptide that can be used to alleviate skin troubles caused by fine dust and inhibits the activity of an aryl hydrocarbon receptor, and a cosmetic composition using the same.

Classes IPC  ?

• C07K 5/10 - Tétrapeptides
• C07K 5/113 - Tétrapeptides la chaîne latérale du premier amino-acide contenant plus de groupes carboxyle que de groupes amino, ou leurs dérivés, p. ex. Asp, Glu, Asn
• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
• A61Q 19/00 - Préparations pour les soins de la peau

Abrégé

The present invention provides a cosmetic composition for suppression or alleviation of seborrhea and a pharmaceutical composition for prevention, alleviation, and treatment of seborrhea, each composition comprising a specific peptide as an active ingredient. The peptide remarkably decreases the interaction between p53 and MDM2, with the consequent remarkable increase of the interaction between p53 and RNA Polymerase II (POLII), whereby the peptide can induce the expression of a cytokine that induces the apoptosis of sebocytes.

Classes IPC  ?

• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
• A61Q 19/00 - Préparations pour les soins de la peau
• A61K 38/06 - Tripeptides
• A61P 17/08 - Antiséborrhéiques
• C07K 5/083 - Tripeptides la chaîne latérale du premier amino-acide étant acyclique, p. ex. Gly, Ala

Abrégé

The present invention provides a pharmaceutical composition for preventing, ameliorating, or treating degenerative diseases caused by cell aging, preferably osteoarthritis or atherosclerosis, comprising a specific peptide as an active ingredient. The peptide remarkably inhibits the interaction of p53 and Forkhead box protein O4 (FOXO4), thereby inhibiting the expression of a cell aging regulator.

Classes IPC  ?

• A61K 38/06 - Tripeptides
• A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p. ex. arthrites, arthroses
• A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale

Abrégé

The present invention relates to peptides inhibiting androgen receptor activity, and a cosmetics composition using same that can be used to alleviate androgen-related diseases such as prostate cancer, skin diseases, alopecia, and the like.

Classes IPC  ?

• C07K 5/093 - Tripeptides la chaîne latérale du premier amino-acide contenant plus de groupes carboxyle que de groupes amino, ou leurs dérivés, p. ex. Asp, Glu, Asn
• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
• A61Q 7/00 - Préparations pour modifier la pousse des cheveux ou des poils
• A61Q 19/00 - Préparations pour les soins de la peau

Abrégé

A low-power, low-noise amplifier with a negative feedback loop is provided. A low noise amplifier (LNA) includes a common gate (CG) amplifier, a common source (CS) amplifier having a gate connected to a source of the CG amplifier, a differential current balancer (DCB) connected to an output end of the CG amplifier and an output end of the CS amplifier, a symmetric load connected to the DCB, and a current bleeding circuit with one end connected to the output end of the CS amplifier and another end connected to the symmetric load, the current bleeding circuit including an active element and a load corresponding to the symmetric load, and an output end of the active element is connected to a gate of the CG amplifier.

Classes IPC  ?

• H03F 3/16 - Amplificateurs comportant comme éléments d'amplification uniquement des tubes à décharge ou uniquement des dispositifs à semi-conducteurs comportant uniquement des dispositifs à semi-conducteurs avec dispositifs à effet de champ
• H03F 1/34 - Circuits à contre-réaction avec ou sans réaction
• H03F 3/50 - Amplificateurs dans lesquels le signal d'entrée est appliqué — ou le signal de sortie est recueilli — sur une impédance commune aux circuits d'entrée et de sortie de l'élément amplificateur, p. ex. amplificateurs dits "cathodynes"
• H03F 3/45 - Amplificateurs différentiels
• H03F 1/22 - Modifications des amplificateurs pour réduire l'influence défavorable de l'impédance interne des éléments amplificateurs par utilisation de couplage dit "cascode", c.-à-d. étage avec cathode ou émetteur à la masse suivi d'un étage avec grille ou base à la masse respectivement
• H03F 3/04 - Amplificateurs comportant comme éléments d'amplification uniquement des tubes à décharge ou uniquement des dispositifs à semi-conducteurs comportant uniquement des dispositifs à semi-conducteurs
• H03F 3/19 - Amplificateurs à haute fréquence, p. ex. amplificateurs radiofréquence comportant uniquement des dispositifs à semi-conducteurs

Abrégé

Disclosed is a radio frequency (RF) amplifier having channel selectivity. The RF amplifier includes a main path including an amplifier, and a feedforward path including a gain/phase compensator, a high-pass filter, and a mixer.

Classes IPC  ?

• H03F 1/32 - Modifications des amplificateurs pour réduire la distorsion non linéaire
• H03F 3/68 - Combinaisons d'amplificateurs, p. ex. amplificateurs à plusieurs voies pour stéréophonie
• H03F 3/195 - Amplificateurs à haute fréquence, p. ex. amplificateurs radiofréquence comportant uniquement des dispositifs à semi-conducteurs dans des circuits intégrés

Abrégé

A low-power double-quadrature receiver is disclosed. The double-quadrature receiver includes a quadrature signal generator configured to generate a first quadrature signal and a second quadrature signal based on each component of a differential input signal, and a switching stage configured to perform down-conversion on the first quadrature signal and the second quadrature signal.

Classes IPC  ?

• H04B 1/16 - Circuits
• H03F 3/45 - Amplificateurs différentiels

Abrégé

A substrate bonding apparatus for bonding a first substrate to a second substrate includes a first bonding chuck supporting the first substrate, a second bonding chuck disposed above the first bonding chuck and supporting the second substrate, a resonant frequency detector detecting a resonant frequency of a bonded structure with the first substrate and the second substrate which are at least partially bonded to each other, and a controller controlling a distance between the first bonding chuck and the second bonding chuck according to the detected resonant frequency of the bonded structure.

Classes IPC  ?

• H01L 21/18 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives les dispositifs ayant des barrières de potentiel, p. ex. une jonction PN, une région d'appauvrissement ou une région de concentration de porteurs de charges les dispositifs ayant des corps semi-conducteurs comprenant des éléments du groupe IV du tableau périodique, ou des composés AIIIBV, avec ou sans impuretés, p. ex. des matériaux de dopage
• B32B 37/00 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons
• B23K 20/10 - Soudage non électrique par percussion ou par une autre forme de pression, avec ou sans chauffage, p. ex. revêtement ou placage utilisant des vibrations, p. ex. soudage ultrasonique
• H01L 21/20 - Dépôt de matériaux semi-conducteurs sur un substrat, p. ex. croissance épitaxiale
• H01L 21/683 - Appareils spécialement adaptés pour la manipulation des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide pendant leur fabrication ou leur traitementAppareils spécialement adaptés pour la manipulation des plaquettes pendant la fabrication ou le traitement des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide ou de leurs composants pour le maintien ou la préhension
• H01L 21/687 - Appareils spécialement adaptés pour la manipulation des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide pendant leur fabrication ou leur traitementAppareils spécialement adaptés pour la manipulation des plaquettes pendant la fabrication ou le traitement des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide ou de leurs composants pour le maintien ou la préhension en utilisant des moyens mécaniques, p. ex. mandrins, pièces de serrage, pinces
• H01L 21/67 - Appareils spécialement adaptés pour la manipulation des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide pendant leur fabrication ou leur traitementAppareils spécialement adaptés pour la manipulation des plaquettes pendant la fabrication ou le traitement des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide ou de leurs composants
• H05K 13/08 - Contrôle de la fabrication des ensembles
• B32B 41/00 - Dispositions pour le contrôle ou la commande des procédés de stratificationDispositions de sécurité
• B32B 37/10 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par la technique de pressage, p. ex. faisant usage de l'action directe du vide ou d'un fluide sous pression
• B32B 38/18 - Manipulation des couches ou du stratifié

Abrégé

Disclosed herein is a method of preparing a white light-emitting material. The method of preparing a white light-emitting material includes the steps of: (a) depositing a metal for the formation of a blue light-emitting material on a substrate by performing thermal evaporation; (b) forming a material in which green and blue light-emitting materials are hybridized by placing the substrate, on which the metal film is deposited in step (a), in a plasma-enhanced chemical vapor deposition (PECVD) reactor and exposing the substrate to silicon (Si) and oxygen (O) in a plasma state; and (c) forming a red light-emitting material in the material formed in step (b) by annealing the material formed in step (b) so that the red, green and blue light-emitting materials are hybridized.

Classes IPC  ?

• H01L 33/02 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs
• H01L 33/50 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les éléments du boîtier des corps semi-conducteurs Éléments de conversion de la longueur d'onde
• C23C 16/50 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement au moyen de décharges électriques
• C23C 16/40 - Oxydes
• C23C 14/14 - Matériau métallique, bore ou silicium
• C23C 14/24 - Évaporation sous vide

Abrégé

The present invention relates to a non-contact portable tonometry system and tonometry method using a difference in infrared intensity. A nozzle module receives compressed air from a compressed air supply source and sprays same through an air spraying port to the cornea of a subject, thereby causing corneal deformation. An infrared sensor is disposed in the nozzle module so as to emit infrared rays to the cornea and measure the amount of light reflected from the cornea. A controller converts the amount of light measured by the infrared sensor before and after the corneal deformation into intraocular pressure.

Classes IPC  ?

• A61B 3/16 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la pression intraoculaire, p. ex. tonomètres
• A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

Paenisporosarcina quisquiliarumPaenisporosarcina quisquiliarum 17mud 1-1541TPaenisporosarcina quisquiliarumPaenisporosarcina quisquiliarum 17mud 1-1541T strain or a culture thereof has very excellent skin lightening and wound healing effects, and thus can be usefully applied as an active ingredient of a pharmaceutical composition, cosmetic composition, or health functional food for skin improvement.

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• A61K 8/99 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de micro-organismes autres que des algues ou des champignons, p. ex. à base de protozoaires ou de bactéries
• A61K 35/74 - Bactéries
• A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
• A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
• A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques
• C12R 1/01 - Bactéries ou actinomycètes

Abrégé

The present invention provides a nanoparticle synthesis device capable of improving productivity of nanoparticles by increasing the size of a reaction region of laser pyrolysis of a source gas.

Classes IPC  ?

• B01J 19/12 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage utilisant des radiations électromagnétiques
• B01J 19/00 - Procédés chimiques, physiques ou physico-chimiques en généralAppareils appropriés
• C01B 33/029 - Préparation par décomposition ou réduction de composés de silicium gazeux ou vaporisés autres que la silice ou un matériau contenant de la silice par décomposition de monosilane

Abrégé

The present invention relates to a bio-electrode having improved conductivity, flexibility and bio-compatibility, and a method of manufacturing the same. Specifically, the present invention relates to a conductive polymer bio-electrode including nano-porous permeable membrane, based on a bio-compatible polymer material having a plurality of pores and an improved surface area based on a PDMS device having a low mechanical strength and an excellent bio-compatibility, bio-signal transmission patterning, and a gold coating layer and has an excellent bio-compatibility and low rejection response while having a conductivity similar to that of a bio-electrode configured with a metal material of the related art. Therefore, the conductive polymer bio-electrode of the present invention is expected to be able to replace a bio-electrode configured with a metal material by which the bio-signal transmission efficiency is degraded due to a high bio-incompatibility.

Classes IPC  ?

• A61L 31/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61B 5/053 - Mesure de l'impédance ou de la conductivité électrique d'une partie du corps
• A61L 31/04 - Matériaux macromoléculaires
• A61L 31/08 - Matériaux de revêtement
• A61L 31/10 - Matériaux macromoléculaires
• B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 40/20 - Posttraitement, p. ex. durcissement, revêtement ou polissage
• B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
• B33Y 80/00 - Produits obtenus par fabrication additive
• C08J 7/04 - Revêtement
• C08J 7/044 - Formation de revêtements conducteursFormation de revêtements ayant des propriétés antistatiques
• D01D 5/00 - Formation des filaments, fils ou similaires
• B29K 83/00 - Utilisation de polymères contenant dans la chaîne principale uniquement du silicium avec ou sans soufre, azote, oxygène ou carbone comme matière de moulage
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites

Abrégé

Disclosed are a non-volatile memory device and a method of operating the non-volatile memory device. A non-volatile memory device in which m logical pages are stored in a single physical page includes: a plurality of registers configured to be included in a flash translation layer (FTL) and to store at least part of the data of a write command received from a file system; and a controller configured to control operations of the plurality of registers based on the write command; wherein each of the plurality of registers is further configured to have a storage space associated with the size of the m logical pages; and wherein the controller is further configured to program the data of the write command into the non-volatile memory device and to store the data of the write command in the plurality of registers.

Classes IPC  ?

• G06F 12/1009 - Traduction d'adresses avec tables de pages, p. ex. structures de table de page
• G06F 12/0891 - Adressage d’un niveau de mémoire dans lequel l’accès aux données ou aux blocs de données désirés nécessite des moyens d’adressage associatif, p. ex. mémoires cache utilisant des moyens d’effacement, d’invalidation ou de réinitialisation
• G06F 3/06 - Entrée numérique à partir de, ou sortie numérique vers des supports d'enregistrement
• G06F 9/30 - Dispositions pour exécuter des instructions machines, p. ex. décodage d'instructions

Abrégé

The present disclosure relates to an anode active material for a lithium secondary battery, a method of manufacturing the anode active material, and a lithium secondary battery including the anode active material. The anode active material includes natural graphite particles configured such that flaky natural graphite fragment particles having uneven (□□) surface defects are structured in a cabbage shape or at random and granulated, the surface and the inside of the natural graphite particles including a gap formed between the flaky natural graphite fragment particles, and a coating layer including amorphous or semicrystalline carbon formed on the surface of the flaky natural graphite fragment particles that form the gap and the surface of the natural graphite particles.

Classes IPC  ?

• H01B 1/04 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisésEmploi de matériaux spécifiés comme conducteurs composés principalement soit de compositions à base de carbone-silicium, soit de carbone soit de silicium
• H01M 4/587 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
• C01B 32/20 - Graphite
• C01B 32/23 - Oxydation
• H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
• H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
• H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif

Abrégé

The present invention relates to a hot-press gas grafting hydrophobization apparatus, and heat- and water-resistant paper and oil-absorbing paper manufactured using same. The apparatus of the present invention provides a non-permeable dryer belt which covers and presses a drying roller so as to prevent dissipation of fatty acid chloride material vaporized by the drying roller, thereby improving gas grafting reaction efficiency.

Classes IPC  ?

• D21H 23/70 - Procédés multi-étapesAppareils pour ajouter au papier une ou plusieurs substances par portions ou de différentes manières, non couverts par un seul autre groupe du présent groupe principal
• D21H 23/56 - Rouleaux
• D21H 23/50 - Pulvérisation ou projection
• D21H 17/36 - Alcools polyalcényliquesÉthers polyalcényliquesEsters polyalcényliques
• D21H 21/16 - Agents de collage ou hydrophobes
• D21H 21/34 - Ignifugeants
• D21H 27/00 - Papier particulier non prévu ailleurs, p. ex. obtenu par des procédés multi-étapes

Abrégé

The present invention provides a nanoparticle synthesis apparatus capable of improving productivity of nanoparticles by increasing the laser pyrolysis reaction region of a source gas. [Representative drawing] figure 1

Classes IPC  ?

• B01J 6/00 - CalcinationCuisson
• B01J 19/12 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage utilisant des radiations électromagnétiques

Abrégé

Disclosed is an attachable/detachable device for repeatedly measuring food texture. To this end, the present invention comprises: a holder having a probe guide installed therein, the probe guide having a predetermined guide hole formed at the center thereof and extending downward while having a predetermined inner space; a cylindrical probe which moves up and down while surrounding the probe guide and has multiple holes formed at the bottom surface thereof so as to allow food to be partially extracted therethrough depending on the degree of compression when the food is compressed; a food sample cup having an inner space in which food can be placed, and positioned below the cylindrical probe; and multiple position fixing guides disposed between the holder and the food sample cup.

Classes IPC  ?

• G01N 33/02 - Nourriture
• G01N 3/02 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique Parties constitutives

Abrégé

The present invention relates to a cell-based vaccine mediated by B cells loaded with a ligand of natural killer T cells and an antigen. Specifically, the present invention relates to a cell-based vaccine exhibiting an excellent antituberculous effect by using α-galactosylceramide (αGC) as a ligand of natural killer T cells, and using ESAT6 as an antigen. The present invention provides a cell-based vaccine whereby, among antigens of tuberculosis, ESAT6 is targeted and expressed in vaccinia virus, and thus antigen transfer is maximized, and after transducing same to B cells, αGC, which is a ligand of natural killer T cells, is loaded, and thus the cell-based vaccine exhibits an effective immune response-inducing effect and a CFU reduction effect against infections.

Classes IPC  ?

• A61K 31/7032 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un polyol, c.-à-d. composés ayant plusieurs groupes hydroxyle, libres ou estérifiés, y compris le groupe hydroxyle impliqué dans la liaison glycosidique, p. ex. monoglucosyl-diacylglycérides, acide lactobionique, gangliosides
• A61K 35/17 - LymphocytesLymphocytes BLymphocytes TCellules tueuses naturellesLymphocytes activés par un interféron ou une cytokine
• A61K 39/04 - Mycobacterium, p. ex. Mycobacterium tuberculosis
• A61P 31/06 - Agents antibactériens pour le traitement de la tuberculose

Abrégé

According to the present invention, an endoscopic medical device with improved bidirectional bending function and ease of use consisting of a main body (10) equipped with a space (S) for rotating/locking at the upper portion of a handle (12), a catheter (20) coupled to the upper portion of the main body (10), a bending adjusting portion (30) to which a wire (W: W1, W2) is coupled so that a distal end portion of the catheter (20) is bent by tensile force by a reciprocal rotation about a rotation shaft (14) at the upper portion of the main body (10), a first elastic portion (40) for applying an elastic force in a reverse rotational direction to the bending adjust portion (30), and a locking portion (50) for stopping the rotation of the bending adjusting portion (30) latched by the application of the elastic force to the bend adjusting portion (30) is provided.

Classes IPC  ?

• A61B 1/005 - Endoscopes flexibles

Abrégé

in vivoin vivo yield and thus can be effectively used as a bioorgan.

Classes IPC  ?

• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
• C01G 5/00 - Composés de l'argent

Abrégé

A mastication simulation system is provided. To this end, the present invention comprises: a main body having a load cell installed therein and comprising a base having a predetermined height; an upper teeth probe which is connected to a driving unit provided on the main body, moves vertically, and has a plurality of flow paths formed therein; a temperature maintenance unit which has a predetermined space for installing a lower teeth probe therein and is positioned on the base; a thermostatic water tank provided on one side of the temperature maintenance unit such that water at a set temperature can be provided to and drained from the temperature maintenance unit; an artificial saliva supply unit for supplying artificial saliva to the plurality of flow paths formed on the upper teeth probe; a control unit which is for controlling the operation of the driving unit, the temperature of the thermostatic water tank and the operation of the artificial saliva supply unit, sensing the load measured by means of the load cell, storing a set strain rate of food, which is placed on the lower teeth probe, due to the descent of the upper teeth probe, and enabling the descent of the upper teeth probe at set speed and by a set number of times and thus enabling mastication of the food; and a display unit for displaying a graph corresponding to the load measured by means of the load cell and the time in accordance with the mastication.

Classes IPC  ?

• G01N 33/02 - Nourriture

Abrégé

The present invention relates to a three-dimensional cell culturing microchip having a nanoporous permeable membrane attached thereto and a fabrication method therefor. The present invention can culture cells in a three-dimensional manner with the nanoporous permeable membrane serving as a cell scaffold and can inject cells by means of a plurality of microfluidic channels or provide a drug, a cell-secreted substance, or a biologically active material through diffusion.

Classes IPC  ?

• C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
• B01D 71/06 - Matériaux organiques

Abrégé

The present invention relates to an adsorption material, which is prepared by recycling waste paper as an eco-friendly circulatory paper resource, for the purpose of adsorption and removal of sea oil spills and other oils, and to a preparation method therefor. An oil adsorption material of the present invention prepared by performing a hydrophobization treatment on a biomass material, such as waste paper, using a gas-phase grafting method has a superior oil absorption rate due to excellent oil absorption selectivity thereof compared with a conventional oil adsorption material formed of a synthetic resin, and also has a low water absorption rate, facilitating an incineration disposal procedure for disposing of an oil adsorption material for disposal having adsorbed oil; the oil adsorption material is formed of an eco-friendly material, leading to less harmful substances generated during combustion; and a biomass material is hydrophobized by using plant fatty acids, leading to a degradation in a short time at the time of a landfill treatment, and thus there is no concern about environmental pollution. Furthermore, the oil adsorption material of the present invention, compared with a conventional oil adsorption material using a synthetic resin, is cheap due to the use of a recycling base material (waste paper), and can be mass-produced using hydrophobization treatment equipment, leading to low preparation costs.

Classes IPC  ?

• B01J 20/24 - Composés macromoléculaires d'origine naturelle, p. ex. acides humiques ou leurs dérivés
• B01J 2/30 - Procédés ou dispositifs pour la granulation de substances, en généralTraitement de matériaux particulaires leur permettant de s'écouler librement, en général, p. ex. en les rendant hydrophobes en utilisant des agents empêchant le collage des granules entre euxTraitement de matériaux particulaires leur permettant de s'écouler librement, en général, p. ex. en les rendant hydrophobes
• E02B 15/10 - Dispositifs pour enlever les substances de la surface
• B32B 23/04 - Produits stratifiés composés essentiellement de substances cellulosiques plastiques comprenant de telles substances comme seul composant ou comme composant principal d'une couche adjacente à une autre couche d'une substance spécifique
• B32B 37/10 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par la technique de pressage, p. ex. faisant usage de l'action directe du vide ou d'un fluide sous pression

Abrégé

The present invention relates to a PDMS or PMMA based microchip having a vertically and permanently fixed functional nano-permeable membrane and a manufacturing method therefor. According to the present invention, the PDMS or PMMA based microchip having a vertically fixed nano-permeable membrane can be applied to a micro-fluidic reaction system using, as a principle, a physical and chemical reaction by selective material transfer occurring between samples that are spatially separated by the nano-permeable membrane.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes

Abrégé

The present invention relates to an antibody specifically binding to a macrophage inhibitory cytokine 1 (MIC-1) protein, and a use thereof.

Classes IPC  ?

• C07K 16/24 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des cytokines, des lymphokines ou des interférons
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
• G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

The present invention relates to a bioelectrode having improved conductivity, flexibility, and biocompatibility, and a method for manufacturing the same. Particularly, the present invention relates to a conductive polymer bioelectrode comprising a biocompatible polymer substance-based nanoporous permeable membrane having a plurality of pores and an improved surface area, a biosignal transferring pattern layer, and a gold coating layer, based on a PDMS device having low mechanical strength and excellent biocompatibility, whereby the conductive polymer bioelectrode is similar in conductivity to that of a conventional metallic bioelectrode and shows excellent biocompatibility, with the incurrence of a low rejection response. Therefore, it is expected that the conductive polymer bioelectrode of the present invention can replace a metallic bioelectrode, which has poor biosignal transfer efficiency due to the high bioincompatibility thereof.

Classes IPC  ?

• A61B 5/04 - Mesure de signaux bioélectriques du corps ou de parties de celui-ci

Abrégé

Provided are an imidazo[1,2-a]pyridine-3-carboxylate derivative and a preparation method thereof, and more particularly, a method of effectively preparing an imidazo[1,2-a]pyridine-3-carboxylate derivative by performing an aza-[3+2] cycloaddition reaction of a pyridine derivative with an α-diazo oxime ether derivative in the presence of a copper (II) catalyst, and an imidazo[1,2-a]pyridine-3-carboxylate derivative prepared thereby.

Classes IPC  ?

• C07D 471/04 - Systèmes condensés en ortho
• B01J 31/04 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques contenant des acides carboxyliques ou leurs sels

Abrégé

Disclosed is a low noise amplifier including a current bleeding circuit. The low noise amplifier includes a common gate amplifier, a common source amplifier of which a gate is connected to a source of the common gate amplifier, a symmetric load connected to an output end of the common gate amplifier and an output end of the common source amplifier, and a current bleeding circuit of which one end is connected to the output end of the common source amplifier and another end is connected to the symmetric load, and including an active element and a load corresponding to the symmetric load.

Classes IPC  ?

• H03F 1/26 - Modifications des amplificateurs pour réduire l'influence du bruit provoqué par les éléments amplificateurs
• H03F 3/193 - Amplificateurs à haute fréquence, p. ex. amplificateurs radiofréquence comportant uniquement des dispositifs à semi-conducteurs comportant des dispositifs à effet de champ
• H03F 1/22 - Modifications des amplificateurs pour réduire l'influence défavorable de l'impédance interne des éléments amplificateurs par utilisation de couplage dit "cascode", c.-à-d. étage avec cathode ou émetteur à la masse suivi d'un étage avec grille ou base à la masse respectivement
• H03F 3/45 - Amplificateurs différentiels

Abrégé

As an embodiment of the present invention, an integrated digital low dropout regulator is provided. The integrated digital low dropout regulator according to an embodiment of the present invention may comprise: a detection unit for detecting whether a coarse voltage is regulated or a fine voltage is regulated, on the basis of a reference voltage and an output voltage for the regulator; a control unit including a self-oscillating bidirectional shift register unit connected to the detection unit and operable to have a minimized transient response time (TTRAN) according to a load connected to the regulator; and a plurality of coarse switches and a plurality of fine switches, connected to the control unit, wherein the control unit is free of a clock input from the outside, and an external load capacitor is eliminated from the regulator.

Classes IPC  ?

• H02M 1/08 - Circuits spécialement adaptés à la production d'une tension de commande pour les dispositifs à semi-conducteurs incorporés dans des convertisseurs statiques
• H02M 3/156 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation

Abrégé

Provided in the present invention are an insulin A-chain derived peptide fragment and a pharmaceutical composition for preventing or treating diabetes or diabetic wounds, containing the same as an active ingredient. The peptide of the present invention induces endocytosis through insulin receptors, has activities of increasing glucose uptake of cells by translocating glucose transporters onto a cell membrane, and of increasing cell migration and proliferation. Therefore, the peptide of the present invention can be usefully applicable in the prevention or treatment of diabetes or diabetic wounds.

Classes IPC  ?

• C07K 5/083 - Tripeptides la chaîne latérale du premier amino-acide étant acyclique, p. ex. Gly, Ala
• C07K 5/103 - Tétrapeptides la chaîne latérale du premier amino-acide étant acyclique, p. ex. Gly, Ala
• A61K 38/06 - Tripeptides
• A61K 38/07 - Tétrapeptides

Abrégé

The present invention relates to a pharmaceutical composition for preventing or treating cancer, containing: an antibody specifically binding to an L1CAM protein; and a pyrimidine analogue, a platin-based anticancer drug, or a combination thereof. Compared to when administrating each ingredient individually, when co-administering an antibody specifically binding to an L1CAM protein with gemcitabine, which is a type of pyrimidine analogue, and/or cisplatin, which is a type of platin-based anticancer drug, synergistic effects are exhibited on the inhibition of bile duct cancer growth, and thus the pharmaceutical composition, of the present invention, containing the antibody and the drug can be usable in the treatment of biliary tract cancer.

Classes IPC  ?

• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61K 31/7068 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées ayant des groupes oxo liés directement au cycle pyrimidine, p. ex. cytidine, acide cytidylique
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

The present invention relates to a method for determining patient-specific blood vessel information. More specifically, the present invention relates to a method for determining patient-specific cardiovascular information by applying a simplified coronary circulation model thereto. Furthermore, the present invention relates to a method for determining a blood flow rate for branches of a blood vessel having originated from an artery of each patient. According to the present invention, the method for determining cardiovascular information by using a computer system comprises the steps of: receiving image data including a plurality of coronary arteries having originated from the aorta; processing the image data so as to generate a three-dimensional shape model of the plurality of coronary arteries; simulating a blood flow for the generated three-dimensional shape model of the plurality of coronary arteries; and determining a fractional flow reserve (FFR) of the respective coronary arteries with the blood flow simulation result. In the blood flow simulation step for the three-dimensional shape model of the plurality of coronary arteries, a computational fluid dynamics model is applied to the three-dimensional shape model of the coronary arteries, and a centralized parameter model to be combined with the computational fluid dynamics model uses a simplified coronary circulation model including coronary arteries, capillaries of the coronary arteries, and coronary veins.

Classes IPC  ?

• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• G06F 17/11 - Opérations mathématiques complexes pour la résolution d'équations

Abrégé

The present invention relates to an air vibration dry-type specific gravity separator for separating, by specific gravity, a mixture having particles of different specific gravities mixed therein, and discharging same, and especially, to an air vibration dry-type specific gravity separator comprising: a blower; a main body having formed therein an airflow forming space for guiding air provided from the blower upward; a separating deck comprising a frame and a mesh table, the frame being incliningly installed at a predetermined angle on the upper part of the main body, and the mesh table being installed on the upper side of the frame so as to have air introduced through the airflow forming space pass therethrough, and having a mixture to be separated placed on the upper surface thereof; and a vibration applying part for applying vibration to the separating deck, wherein the mesh table comprises a wrinkle part and a flat part, the wrinkle part having the mixture supplied thereto, and having a plurality of wrinkles formed thereon so that peaks and troughs are continuously repeated, and the flat part being integrally formed with the wrinkle part, and thus the present invention has the advantage of being capable of increasing efficiency in separating heavy particles (particles having high specific gravities) from light particles (particles having low specific gravities).

Classes IPC  ?

• B07B 4/08 - Séparation des solides, obtenue en soumettant leur mélange à des courants de gaz pendant que le mélange est supporté par des cribles, des tamis ou des éléments mécaniques analogues
• B07B 1/28 - Tamis mobiles non prévus ailleurs, p. ex. à oscillations, à mouvement alternatif, à balancement, à basculement ou à vacillement
• B07B 1/46 - Éléments de structure constitutifs des tamis en généralNettoyage ou chauffage des tamis
• B03B 4/02 - Séparation par tables pneumatiques ou bacs à piston pneumatiques en utilisant des tables basculantes ou à secousses
• B07B 13/08 - Classement ou triage des matériaux solides par voie sèche non prévu ailleursTriage autrement que par des dispositifs commandés indirectement selon le poids

Abrégé

The present invention relates to a multi-stage eddy current separator used for separating nonmetals from non-ferrous metals in a mixture of nonmetals and non-ferrous metals, and especially, to a multi-stage eddy current separator comprising: a support frame formed so that one side thereof is high, and the height thereof becomes lower towards the other side thereof; and unit separators installed on the support frame so as to be able to be tilted, wherein the number of the installed unit separators increases towards a lower position from a high position, and thus the present invention has the effect of being capable of enhancing efficiency in separating since a mixture of nonmetals and non-ferrous metals is separated in a unit separator disposed in a high position, and then the separated mixture is provided to a unit separator disposed in a low position where the nonmetals and non-ferrous metals are separated again.

Classes IPC  ?

• B03C 1/22 - Séparation magnétique agissant directement sur la substance à séparer ayant des supports pour le matériau traité en forme de bandes avec des aimants fixes
• B07B 13/00 - Classement ou triage des matériaux solides par voie sèche non prévu ailleursTriage autrement que par des dispositifs commandés indirectement
• B65G 15/00 - Transporteurs comportant des surfaces porteuses de charges sans fin, c.-à-d. des tapis roulants ou autres systèmes équivalents, auxquelles l'effort de traction est transmis par des moyens différents des éléments d'entraînement sans fin de même configuration
• B65G 21/12 - Châssis ou carters de support ou de protection pour transporteurs sans fin ou éléments de traction des transporteurs à courroies ou à chaînes mobiles ou à pièces interchangeables ou relativement mobilesDispositifs pour déplacer le châssis ou des parties de celui-ci pour permettre le réglage de la position du porte-charges de l'élément de traction dans son ensemble
• B65G 41/00 - Châssis ou bases de support pour transporteurs dans leur ensemble, p. ex. châssis transportables
• B65G 37/00 - Combinaisons de transporteurs mécaniques de même type ou de types différents sauf en ce qui concerne leur application dans des machines particulières ou leur emploi dans des procédés particuliers de fabrication

Abrégé

The present invention relates to an activated carbon recycling apparatus for recycling activated carbon used to remove a residual-solvent extracting reagent contained in wastewater of a solvent extracting process, the apparatus particularly comprising: a transfer unit including a transfer tube, a transfer screw, and a motor, wherein the transfer tube has a hopper provided on one side thereof for supplying activated carbon and an outlet provided on an opposite side thereof for discharging the activated carbon, the transfer screw is installed within the transfer tube so as to be rotatable, and the motor rotates the transfer screw to transfer the activated carbon toward the outlet; an electric furnace installed to surround the outer surface of the transfer tube and gasifying a residual solvent adsorbed onto the activated carbon by heating the same; and a hood installed above the hopper to generate a suction force to suction the gas gasified by the electric furnace. Accordingly, the present invention can efficiently remove organic solvents, such as D2EPHA, PC88A, kerosene, and the like, which have been adsorbed onto the activated carbon and can reduce a load applied to the electric furnace.

Classes IPC  ?

• B01J 20/34 - Régénération ou réactivation

Abrégé

Provided are novel cyclic phosphinate derivatives and a method of preparing the same, and more particularly, cyclic phosphinate derivatives including benzoxaphosphole oxide derivatives and benzoxaphosphorin oxide derivatives, and a method of preparing the same. The cyclic phosphinate derivative according to the present invention may have pharmacological and physiological activities, be used as the basic skeleton of the natural material, and be used in development of a new drug, and synthesis of various medicines. In addition, with the method of preparing a cyclic phosphinate derivative according to the present invention, various cyclic phosphinate derivatives may be prepared with high yield through a simple synthetic process by performing an intramolecular carbon-oxygen coupling reaction on the phosphinic acid derivative in the presence of a palladium (Pd) catalyst, an oxidant, and a base.

Classes IPC  ?

• C07F 9/6571 - Composés hétérocycliques, p. ex. contenant du phosphore comme hétéro-atome du cycle comportant des atomes de phosphore, avec ou sans atomes d'azote, d'oxygène, de soufre, de sélénium ou de tellure, comme hétéro-atomes du cycle comportant des atomes de phosphore et d'oxygène comme uniques hétéro-atomes du cycle
• C07F 9/6574 - Esters des oxyacides du phosphore

Abrégé

A method is for simultaneously analyzing nutritional component content in a plurality of various foods or agricultural sources having different ingredients and forms, that is, different physicochemical properties and compositions distributed in Korea by near-infrared reflectance spectroscopy. In particular, a method is for rapidly and accurately measuring nutritional component content in a plurality of various foods or agricultural sources having different ingredients and forms, that is, different physicochemical properties and compositions distributed in Korea by near-infrared reflectance spectroscopy.

Classes IPC  ?

• G01N 21/359 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge en utilisant la lumière de l'infrarouge proche
• G01N 33/02 - Nourriture
• G01N 21/25 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes
• G01N 21/31 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique
• G01N 21/27 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en utilisant la détection photo-électrique

Abrégé

A supporting unit is provided. The supporting unit includes a body, an alignment member, at least one sensor, and a controller. The body has a top surface supporting a target object. The alignment member is disposed in the body and adjusts a position of the target object. The sensor senses the position of the target object. The controller controls the alignment member and the sensor member. The alignment member includes a magnet that adjusts the position of the target object according to an electromagnetic force; and a coil that applies the electromagnetic force to the magnet.

Classes IPC  ?

• H01F 1/00 - Aimants ou corps magnétiques, caractérisés par les matériaux magnétiques appropriésEmploi de matériaux spécifiés pour leurs propriétés magnétiques
• H01L 21/00 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de dispositifs à semi-conducteurs ou de dispositifs à l'état solide, ou bien de leurs parties constitutives

Abrégé

The present invention relates to a vaccine composition for prevention of Mycoplasma hyopneumoniae (M. hyopneumoniae) infection in pigs, and a preparation method thereof, wherein the composition comprises a recombinant protein derived from M. hyopneumoniae and an M. hyopneumoniae bacterin. The recombinant protein of the present invention allows the vaccine to exhibit a superior protective effect over the conventional vaccine by increasing the immune response against M. hyopneumoniae bacterin, and thus the vaccine composition of the present invention can effectively prevent diseases caused by M. hyopneumoniae infection in pigs, in particular, Swine enzootic pneumonia.

Classes IPC  ?

• C12N 15/09 - Technologie d'ADN recombinant
• A61K 39/02 - Antigènes bactériens
• A61P 31/12 - Antiviraux
• A61P 1/12 - Antidiarrhéiques

Abrégé

The present invention provides: a peptide fragment derived from secreted frizzled protein 5 (Sfrp5), that is, a peptide fragment selected from the group consisting of peptides composed of amino acid sequences of SEQ ID NOs: 1 to 9; and a cosmetic composition, containing the same as an active ingredient, for skin whitening and/or skin pigmentation suppression. The peptide fragment has an activity to suppress skin pigmentation by inhibiting melanogenesis in melanin cells. In addition, the present invention provides reagents for research or analysis, containing the peptide fragment to suppress Wnt signaling.

Classes IPC  ?

• C07K 5/00 - Peptides ayant jusqu'à quatre amino-acides dans une séquence entièrement déterminéeLeurs dérivés
• C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
• A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet

Abrégé

The present invention relates to a method for determining patient-specific blood vessel information. More specifically, the present invention relates to a method for determining patient-specific cardiovascular information by applying a simplified coronary circulation model thereto. Furthermore, the present invention relates to a method for determining a blood flow rate for branches of a blood vessel having originated from an artery of each patient. According to the present invention, the method for determining cardiovascular information by using a computer system comprises the steps of: receiving image data including a plurality of coronary arteries having originated from the aorta; processing the image data so as to generate a three-dimensional shape model of the plurality of coronary arteries; simulating a blood flow for the generated three-dimensional shape model of the plurality of coronary arteries; and determining a fractional flow reserve (FFR) of the respective coronary arteries with the blood flow simulation result. In the blood flow simulation step for the three-dimensional shape model of the plurality of coronary arteries, a computational fluid dynamics model is applied to the three-dimensional shape model of the coronary arteries, and a centralized parameter model to be combined with the computational fluid dynamics model uses a simplified coronary circulation model including coronary arteries, capillaries of the coronary arteries, and coronary veins.

Classes IPC  ?

• G06F 19/00 - Équipement ou méthodes de traitement de données ou de calcul numérique, spécialement adaptés à des applications spécifiques (spécialement adaptés à des fonctions spécifiques G06F 17/00;systèmes ou méthodes de traitement de données spécialement adaptés à des fins administratives, commerciales, financières, de gestion, de surveillance ou de prévision G06Q;informatique médicale G16H)
• A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
• G06Q 50/22 - Aide sociale ou assistance sociale, p. ex. activités de développement communautaire ou services de consultation

Abrégé

Provided is a composition containing peptide fragments or small peptides derived from epidermal growth factor (EGF) for wound healing and inhibiting aging of the skin or formation of skin wrinkles. The peptides activate EGF receptors and have activities promoting keratinocyte proliferation and angiogenesis in the skin. Accordingly, the peptides can be utilized effectively in wound healing and inhibiting aging of the skin or formation of skin wrinkles.

Classes IPC  ?

• A61K 38/07 - Tétrapeptides
• A61K 38/06 - Tripeptides
• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
• A61Q 19/08 - Préparations contre le vieillissement

Abrégé

Provided is a composition containing peptide fragments or small peptides derived from fibroblast growth factor (FGF) for wound healing or inhibiting aging of the skin or formation of skin wrinkles. The peptides activate FGF receptors to induce collagen synthesis and have activities promoting keratinocyte proliferation and angiogenesis in the skin. Accordingly, the peptides can be effectively utilized in wound healing and inhibiting aging of the skin or formation of skin wrinkles.

Classes IPC  ?

• A61K 38/06 - Tripeptides
• A61K 38/07 - Tétrapeptides
• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
• A61Q 19/08 - Préparations contre le vieillissement

Abrégé

Provided are a novel phosphinine oxide derivative and a preparation method thereof, and more specifically, the phosphinine oxide derivative includes an oxaphosphinine oxide derivative and an azaphosphinine oxide derivative. The phosphinine oxide derivative according to the present invention may have a pharmacological activity and a physiological activity, and may be used as a basic framework of a natural product and may be used for development of new drug and synthesis of various medical supplies. In addition, according to the preparation method of the phosphinine oxide derivative according to the present invention, various phosphinine oxide derivatives with a high yield may be prepared by a simple synthesis process using an intramolecular annulation between a phosphinic derivative and an alkyne derivative in the presence of a rhodium (Rh) catalyst or a ruthenium (Ru) catalyst and an oxidant.

Classes IPC  ?

• C07F 9/6584 - Composés hétérocycliques, p. ex. contenant du phosphore comme hétéro-atome du cycle comportant des atomes de phosphore, avec ou sans atomes d'azote, d'oxygène, de soufre, de sélénium ou de tellure, comme hétéro-atomes du cycle comportant des atomes de phosphore et d'azote, avec ou sans atomes d'oxygène ou de soufre, comme hétéro-atomes du cycle comportant un atome de phosphore comme hétéro-atome du cycle
• C07F 9/6571 - Composés hétérocycliques, p. ex. contenant du phosphore comme hétéro-atome du cycle comportant des atomes de phosphore, avec ou sans atomes d'azote, d'oxygène, de soufre, de sélénium ou de tellure, comme hétéro-atomes du cycle comportant des atomes de phosphore et d'oxygène comme uniques hétéro-atomes du cycle

Abrégé

Provided are novel cyclic phosphinate derivatives and a method of preparing the same, and more particularly, cyclic phosphinate derivatives including benzoxaphosphole oxide derivatives and benzoxaphosphorin oxide derivatives, and a method of preparing the same. The cyclic phosphinate derivative according to the present invention may have pharmacological and physiological activities, be used as the basic skeleton of the natural material, and be used in development of a new drug, and synthesis of various medicines. In addition, with the method of preparing a cyclic phosphinate derivative according to the present invention, various cyclic phosphinate derivatives may be prepared with high yield through a simple synthetic process by performing an intramolecular carbon-oxygen coupling reaction on the phosphinic acid derivative in the presence of a palladium (Pd) catalyst, an oxidant, and a base.

Classes IPC  ?

• C07F 9/6571 - Composés hétérocycliques, p. ex. contenant du phosphore comme hétéro-atome du cycle comportant des atomes de phosphore, avec ou sans atomes d'azote, d'oxygène, de soufre, de sélénium ou de tellure, comme hétéro-atomes du cycle comportant des atomes de phosphore et d'oxygène comme uniques hétéro-atomes du cycle
• C07F 9/6584 - Composés hétérocycliques, p. ex. contenant du phosphore comme hétéro-atome du cycle comportant des atomes de phosphore, avec ou sans atomes d'azote, d'oxygène, de soufre, de sélénium ou de tellure, comme hétéro-atomes du cycle comportant des atomes de phosphore et d'azote, avec ou sans atomes d'oxygène ou de soufre, comme hétéro-atomes du cycle comportant un atome de phosphore comme hétéro-atome du cycle
• C07F 9/6574 - Esters des oxyacides du phosphore

Abrégé

The present invention relates to a method for simultaneously analyzing, by using near-infrared spectroscopy, the quantities of nutritional content contained in a plurality of kinds of domestically distributed food and agricultural resources having various raw materials and shapes and, more specifically, to a method for quickly and accurately measuring, by using near-infrared spectroscopy, the quantities of various nutritional contents contained in the plurality of kinds of domestically distributed food and agricultural resources having various raw materials and shapes.

Classes IPC  ?

• G01N 21/25 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes
• G01N 21/31 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique
• G01N 33/02 - Nourriture

Abrégé

According to the present invention, chatting corpus data, which comprises user utterance data and system response data, is received as learning data; learning is conducted to generate index information between the user utterance data and the system response data; when the user utterance data is a compound sentence, a mutual information amount in connection with the system response data is calculated with regard to each of simple sentences that constitute the compound sentence; one of the simple sentences is selected on the basis of the mutual information amount; learning data is generated using data regarding the selected simple sentence and the system response data; and re-learning is conducted, thereby providing system response data which is reliable in connection with compound sentences as well. In addition, according to the present invention, when user utterance data is input, system response data corresponding to the user utterance data is detected and output; or, when no system response data is detected and when the user utterance data is a compound sentence, system response data corresponding to each of simple sentences constituting the compound sentence is detected; a mutual information amount between the detected system response data and the simple sentences is calculated; and one of pieces of system response data is selected and output on the basis of the mutual information amount, thereby providing system response data which is reliable in connection with compound sentences as well.

Classes IPC  ?

• G06Q 50/20 - Éducation
• G06Q 50/30 - Transport; Communications

Abrégé

The present invention relates to Bacillus amyloliquefaciens EBN-TK3, which was verified to have an excellent antibacterial effect of inhibiting bacteria, especially, Bordetella Bronchiseptica, which is an organism that causes atrophic rhinitis of swine, and Salmonella gallinarum, which is an organism that causes fowl typhoid, in swine and poultry industries. The Bacillus amyloliquefaciens EBN-TK3 was also verified to have an antifungal effect of suppressing and inhibiting Rhizoctonia solani, which is an organism that causes sheath blight causing diseases in crops, Fusarium oxysporum f.sp. raphani, which is an organism that causes wilting disease, and Fusarium oxysporum f.sp. niveum, which is an organism that causes dead-arm disease.

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• A61K 35/74 - Bactéries
• A23K 1/17 - avec des antibiotiques

Abrégé

The present invention provides newly isolated Alcaligenes faecalis EBN-NS13 (KCTC 12471BP). The strain of the present invention and a culture solution thereof can be simultaneously applied to nitrification and denitrification and exhibit remarkable nitrification and denitrification capacities.

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• C02F 3/34 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout caractérisé par les micro-organismes utilisés

Abrégé

Provided is a pharmaceutical or cosmetic composition comprising, as an active ingredient, a peptide fragment derived from adiponectin, that is, a peptide selected from the group consisting of peptides comprising amino acid sequences having sequence numbers 1-6. The peptide promotes skin regeneration and moisturization, and has a suppression activity for wrinkles of the skin, and additionally, has suppression activities for allergy or inflammation and metastasis of cancer cells.

Classes IPC  ?

• C07K 5/08 - Tripeptides
• C07K 5/10 - Tétrapeptides
• C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
• A61K 38/06 - Tripeptides

Abrégé

The present invention provides small peptide fragments derived from microphthalmia-associated transcription factor (MITF), and a pharmaceutical composition for preventing or treating melanoma, containing the same as active ingredients. In addition, the present invention provides a cosmetic composition for skin whitening and/or skin pigmentation suppression, containing the peptide fragments as active ingredients.

Classes IPC  ?

• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
• A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
• A61Q 19/00 - Préparations pour les soins de la peau

Abrégé

The present invention relates to a horizontal arrangement type tension compression tester, and the components thereof comprise: a sample base unit on which a sample is mounted; a static load applying unit which presses and fixes the sample which is mounted on the sample base unit in the vertical direction; a fixing unit which supports both ends of the sample which is mounted on the sample base unit; a dynamic load applying unit which operates so as to apply tension or compression force to the sample which is mounted on the sample base unit; a temperature control unit which controls temperature such that the sample which is mounted on the sample base unit has predetermined temperature; and a control unit which detects a load and a change in the state of the sample according to the operation of the dynamic load applying unit, and which controls the operations of each component.

Classes IPC  ?

• G01N 3/14 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique par application d'efforts permanents de traction ou de compression engendrés par poids mort, p. ex. penduleRecherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique par application d'efforts permanents de traction ou de compression engendrés par la tension d'un ressort

Abrégé

The present invention relates to a novel antibody binding specifically to human and mouse L1CAM protein, and, more specifically, relates to: an antibody exhibiting a high ability to bind to both human and mouse L1CAM (L1 cell adhesion molecule) protein, wherein there is a variation in the sequence of an antibody that binds specifically to L1CAM contained in the heavy-chain variable region of sequence number 1 and the light-chain variable region of sequence number 5; a polynucleotide coding for the antibody; an expression vector comprising the polynucleotide; a transformant resulting from the introduction of the vector; a cancer-preventing or -treating pharmaceutical composition comprising the antibody; a method for treating cancer by using the antibody; a cancer-diagnosing composition comprising the antibody; a cancer-diagnosing kit comprising the composition; a method using the antibody in order to provide information for the diagnosis of cancer; and an antibody-drug conjugate in which a drug is bound to the antibody.

Classes IPC  ?

• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• C12N 15/13 - Immunoglobulines
• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61P 35/00 - Agents anticancéreux

Abrégé

The present invention provides small peptide fragments derived from the p65 subunit of NF-κB, and a pharmaceutical composition or cosmetic composition comprising same. The peptides adjust the transactivation function of NF-κB so as to have NF-κB inhibitory activity. The peptides inhibit the expression of various inflammatory mediator molecules, the expression of which is induced by NF-κB activity, and inhibit the extravasation of white blood cells so as to have an anti-inflammatory activity. Particularly, the peptides have excellent inhibitory activity against skin inflammation and skin aging. Further, the peptides inhibit the vascularization and permeation of the basement membrane of cancer cells so as to have an inhibitory activity against the growth and metastasis of cancer cells.

Classes IPC  ?

• A61K 38/07 - Tétrapeptides
• A61K 38/06 - Tripeptides
• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]