THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (Canada)
Inventeur(s)
Wan, Leon
Garg, Shyam
Hauptschein, Robert
Legros, Philippe
Tardi, Paul
Wang, Lucy
Allen, Christine
Abrégé
The present disclosure relates to combinations comprising an ATR inhibitor and a PARP inhibitor and optionally further comprising an additional pharmaceutically active agent. Also provided are certain methods of treatment, e.g., a method for treating cancer such as ovarian cancer, with a combination comprising an effective amount of an ATR inhibitor and an effective amount of a PARP inhibitor and optionally further comprising an additional pharmaceutically active agent. In particular, a combination comprising a liposomal composition of an ATR inhibitor and a liposomal composition of a PARP inhibitor is disclosed herein.
A61K 31/395 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Educational services, namely, arranging and conducting
educational conferences, exhibitions, training courses, and
seminars in the fields of sleep-related health, medicine,
pharmaceuticals, and medical science, and distributing
course material in connection therewith; providing
continuing medical education courses in the fields of
sleep-related health, medicine, pharmaceuticals, and medical
science; publication of texts, other than publicity texts;
publication of scientific and medical texts other than
publicity texts; publication of online texts and articles
other than publicity texts, in the fields of sleep-related
health, medicine, pharmaceuticals, and medical science.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for the treatment, management
and prevention of cancer, psychiatric diseases and
disorders, central nervous system conditions, sleep
disorders, narcolepsy, schizophrenia, cataplexy, obstructive
sleep apnea, and for use in oncological and hematological
diseases and disorders; pharmaceutical preparations for use
in oncology and hematology; pharmaceutical preparations for
the treatment and management of neurological, psychiatric,
and sleep conditions, diseases, and disorders;
pharmaceutical preparations for the treatment and management
of cancer, cataplexy, excessive daytime sleepiness, liver
disease, narcolepsy, obstructive sleep apnea, and
schizophrenia.
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
(1) Educational services, namely, arranging and conducting educational conferences, exhibitions, training courses, and seminars in the fields of sleep-related health, medicine, pharmaceuticals, and medical science, and distributing course material in connection therewith; providing continuing medical education courses in the fields of sleep-related health, medicine, pharmaceuticals, and medical science; publication of texts, other than publicity texts; publication of scientific and medical texts other than publicity texts; publication of online texts and articles other than publicity texts, in the fields of sleep-related health, medicine, pharmaceuticals, and medical science.
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Educational services, namely, arranging and conducting educational conferences, exhibitions, training courses, and seminars in the fields of sleep-related health, medicine, pharmaceuticals, and medical science, and distributing course material in connection therewith; providing continuing medical education courses in the fields of sleep-related health, medicine, pharmaceuticals, and medical science; publication of texts, other than publicity texts; publication of scientific and medical texts other than publicity texts; publication of online texts and nondownloadable articles other than publicity texts, in the fields of sleep-related health, medicine, pharmaceuticals, and medical science
A drug distribution system and method utilizes a central pharmacy and database to track all prescriptions for a sensitive drug. Information is kept in the database regarding all physicians allowed to prescribe the sensitive drug, and all patients receiving the drug. Abuses are identified by monitoring data in the database for prescription patterns by physicians and prescriptions obtained by patients and/or caregivers. Further verification is made that the physician is eligible to prescribe the drug by consulting a separate database, and optionally whether any actions are taken against the physician. Multiple controls beyond those for normal drugs are imposed on the distribution depending on the sensitivity of the drug.
G16H 70/40 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des médicaments, p. ex. leurs effets secondaires ou leur usage prévu
G16H 70/20 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des pratiques ou des directives
G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
G16H 20/13 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients delivrés par des distributeurs
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Educational services, namely, arranging and conducting
medical educational conferences, exhibitions, training
courses, and seminars in the fields of medicine,
pharmaceuticals, and medical science, and distributing
course material in connection therewith; providing
continuing medical education courses; publication of texts,
other than publicity texts; publication of scientific and
medical texts; publication of online texts and articles.
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
(1) Educational services, namely, arranging and conducting medical educational conferences, exhibitions, training courses, and seminars in the fields of medicine, pharmaceuticals, and medical science, and distributing course material in connection therewith; providing continuing medical education courses; publication of scientific papers and medical texts other than publicity texts; publication of online texts and articles other than publicity texts, in the fields of medicine, pharmaceuticals, and medical science
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Medical services, namely, providing health and medical data and information via a database or website; medical services, namely, providing a database featuring patient medical information accessible by doctors, medical service providers, patients, and patient caregivers; medical services, namely, collecting, organizing, managing, monitoring, and sharing medical and health data and information with doctors, medical service providers, patients, and patient caregivers to compare the effectiveness of treatments and patient outcomes for medical treatment and diagnostic purposes; providing medical information via a database or website; health assessment services, namely, providing patient and doctor surveys and questionnaires to collect data and information for treatment and diagnostic purposes; medical services related to sleep disorders, including narcolepsy
10.
Devices and methods for facilitating and controlling use of a medication
A device includes a reservoir configured to store a drug formulation including at least one abuse-preventing additive. The device further includes means configured to remove the at least one abuse-preventing additive. The device further includes means configured to prevent access to the drug formulation.
A61J 3/00 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration
A61J 7/00 - Dispositifs pour administrer les médicaments par voie buccale, p. ex. cuillèresDispositifs pour compter les pilulesDispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments
A61K 31/19 - Acides carboxyliques, p. ex. acide valproïque
A61K 31/191 - Acides acycliques ayant plusieurs groupes hydroxyle, p. ex. acide gluconique
A61K 31/22 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p. ex. pravastatine
A61K 31/485 - Dérivés du morphinane, p. ex. morphine, codéine
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Educational services, namely, arranging and conducting medical educational conferences, exhibitions, training courses, and seminars in the fields of medicine, pharmaceuticals, and medical science, and distributing course material in connection therewith; providing continuing medical education courses; publication of texts, other than publicity texts; publication of scientific and medical texts other than publicity texts; publication of online texts and articles other than publicity texts, in the fields of medicine, pharmaceuticals, and medical science
12.
Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances
Controlled release dosage forms are described herein. The controlled release formulations described herein provide prolonged delivery of high dose drugs that are highly water soluble and highly hygroscopic. In specific embodiments, controlled release dosage forms for delivery of a drug selected from GHB and pharmaceutically acceptable salts, hydrates, tautomers, solvates and complexes of GHB. The controlled release dosage forms described herein may incorporate both controlled release and immediate release formulations in a single unit dosage form.
Controlled release dosage forms are described herein. The controlled release formulations described herein provide prolonged delivery of high dose drugs that are highly water soluble and highly hygroscopic. In specific embodiments, controlled release dosage forms for delivery of a drug selected from GHB and pharmaceutically acceptable salts, hydrates, tautomers, solvates and complexes of GHB. The controlled release dosage forms described herein may incorporate both controlled release and immediate release formulations in a single unit dosage form.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations acting on the central nervous
system; pharmaceutical preparations for use in the treatment
and/or management of sleep disorders and neurological
disorders.
15.
Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances
Controlled release dosage forms are described herein. The controlled release formulations described herein provide prolonged delivery of high dose drugs that are highly water soluble and highly hygroscopic. In specific embodiments, controlled release dosage forms for delivery of a drug selected from GHB and pharmaceutically acceptable salts, hydrates, tautomers, solvates and complexes of GHB. The controlled release dosage forms described herein may incorporate both controlled release and immediate release formulations in a single unit dosage form.
Controlled release dosage forms are described herein. The controlled release formulations described herein provide prolonged delivery of high dose drugs that are highly water soluble and highly hygroscopic. In specific embodiments, controlled release dosage forms for delivery of a drug selected from GHB and pharmaceutically acceptable salts, hydrates, tautomers, solvates and complexes of GHB. The controlled release dosage forms described herein may incorporate both controlled release and immediate release formulations in a single unit dosage form.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment and management of sleep disorders; pharmaceutical preparations for the treatment and management of neurological disorders, namely, central nervous system indications; pharmaceutical preparations for use in the treatment of sleep disorders and neurological disorders, namely, brain injury, spinal cord injury, seizure disorders; pharmaceutical preparations for use in the management of sleep disorders and neurological disorders, namely, brain injury, spinal cord injury, seizure disorders;
18.
Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances
Controlled release dosage forms are described herein. The controlled release formulations described herein provide prolonged delivery of high dose drugs that are highly water soluble and highly hygroscopic. In specific embodiments, controlled release dosage forms for delivery of a drug selected from GHB and pharmaceutically acceptable salts, hydrates, tautomers, solvates and complexes of GHB. The controlled release dosage forms described herein may incorporate both controlled release and immediate release formulations in a single unit dosage form.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Downloadable mobile applications for the collection, exchange and analysis of health and medical data to facilitate the co-management of diseases between health care professionals and healthcare recipients, coordination of care for sleep disorder patients, for providing medical and diagnostic information for patients, caregivers, and health care professionals, and for the management, treatment, and medication adherence for sleep disorders
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing medical information; medical services, namely, assisting patients, caregivers, health care providers, and health care professionals with respect to monitoring, management, and patient adherence to medical treatments; medical services, namely, providing a web site for medical professionals, patients, and caregivers featuring information relating to diagnosis, treatment, and management of sleep disorders
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Medical services, namely, providing patient medical
information, via a database accessible by doctors, medical
service providers, patients, and patient caregivers;
collecting, monitoring, and sharing medical and health data
and information with doctors, medical service providers,
patients, and patient caregivers to compare the
effectiveness of treatments and patient outcomes for medical
treatment and diagnostic purposes; administering health
assessment surveys and questionnaires to collect medical
diagnostic and treatment data and information to be used for
medical treatment and diagnostic medical care services;
medical services related to sleep disorders, including
narcolepsy.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations acting on the central nervous system; pharmaceutical preparations for use in the treatment and/or management of sleep disorders and neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations acting on the central nervous system; pharmaceutical preparations for use in the treatment and/or management of sleep disorders and neurological disorders
24.
Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances
Controlled release dosage forms are described herein. The controlled release formulations described herein provide prolonged delivery of high dose drugs that are highly water soluble and highly hygroscopic. In specific embodiments, controlled release dosage forms for delivery of a drug selected from GHB and pharmaceutically acceptable salts, hydrates, tautomers, solvates and complexes of GHB. The controlled release dosage forms described herein may incorporate both controlled release and immediate release formulations in a single unit dosage form.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations acting on the central nervous
system; pharmaceutical preparations for use in the treatment
and/or management of sleep disorders and neurological
disorders.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment and management of central nervous system disorders; Pharmaceutical preparations for the treatment and management of sleep disorders; pharmaceutical preparations for the treatment and management of neurological disorders, namely, central nervous system indications
The present disclosure provides method of preventing, lessening the effects, or treating cytokine release syndrome (CRS) or related disorders, and/or neurotoxicity associated with immunotherapy comprising administering defibrotide. The defibrotide can be administered after the immunotherapy begins or be administered prophylactically before immunotherapy begins or before the patient develops CRS and/or neurotoxicity.
A61K 31/711 - Acides désoxyribonucléiques naturels, c.-à-d. contenant uniquement des 2'-désoxyriboses liés à l'adénine, la guanine, la cytosine ou la thymine et ayant des liaisons 3'-5' phosphodiester
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations acting on the central nervous system; pharmaceutical preparations for use in the treatment and/or management of sleep disorders and neurological disorders
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Medical services, namely, providing health and medical data and information via a database or website; medical services, namely, providing a database featuring patient medical information accessible by doctors, medical service providers, patients, and patient caregivers; medical services, namely, collecting, organizing, managing, monitoring, and sharing medical and health data and information with doctors, medical service providers, patients, and patient caregivers to compare the effectiveness of treatments and patient outcomes for medical treatment and diagnostic purposes; providing medical information via a database or website; health assessment services, namely, providing patient and doctor surveys and questionnaires to collect data and information for treatment and diagnostic purposes; medical services related to sleep disorders, including narcolepsy
C07C 237/20 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des groupes amino ayant les atomes de carbone des groupes carboxamide liés à des atomes de carbone acycliques du squelette carboné le squelette carboné contenant des cycles aromatiques à six chaînons
C07C 275/18 - Dérivés d'urée, c.-à-d. composés contenant l'un des groupes les atomes d'azote ne faisant pas partie de groupes nitro ou nitroso ayant des atomes d'azote de groupes urée liés à des atomes de carbone acycliques d'un squelette carboné saturé contenant des cycles
C07C 307/02 - Monoamides d'acides sulfuriques ou de leurs esters, p. ex. acides sulfamiques
C07C 333/04 - Acides monothiocarbamiquesLeurs dérivés ayant des atomes d'azote de groupes thiocarbamiques liés à des atomes d'hydrogène ou à des atomes de carbone acycliques
A61K 31/165 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide
A61K 31/17 - Amides, p. ex. acides hydroxamiques ayant le groupe N-C(O)-N ou N-C(S)-N, p. ex. urée, thiourée, carmustine
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Medical information; providing medical information; providing pharmaceutical support services, namely, providing information relating to diagnostic, prophylactic and therapeutic properties of pharmaceutical preparations and providing information relating to medicinal dosage for medical treatment purposes; providing healthcare information, medical information, and pharmaceutical support services in the nature of providing information relating to diagnostic, prophylactic and therapeutic properties of pharmaceutical preparations and safe and appropriate use and distribution of pharmaceuticals for medical treatment purposes; providing medical information relating to patient reimbursement for pharmaceuticals, namely, providing information and counseling regarding patient assistance programs to provide pharmaceuticals and medical treatment; providing medical information regarding patient access, namely, counseling services and information with respect to access to medical treatment, medical care, and pharmaceuticals, all via the Internet and by telephone and distribution of corresponding printed informational materials to patients, physicians, medical office staff, prescribers, and pharmacies
36 - Services financiers, assurances et affaires immobilières
Produits et services
Providing information in insurance matters; insurance consultation; health care insurance consultation in the nature of providing assistance to others in obtaining insurance reimbursement of medical expenses for pharmaceuticals
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
House mark for a line of pharmaceuticals for the treatment, management and prevention of cancer, psychiatric diseases and disorders, central nervous system conditions, sleep disorders, narcolepsy, schizophrenia, cataplexy, obstructive sleep apnea, and for use in oncological and hematological diseases and disorders; Pharmaceutical preparations acting on the central nervous system; pharmaceutical preparations for use in oncology and hematology; pharmaceutical preparations for the treatment and management of neurological, psychiatric, and sleep conditions, diseases, and disorders; pharmaceutical preparations for the treatment and management of cancer, cataplexy, excessive daytime sleepiness, liver disease, narcolepsy, obstructive sleep apnea, and schizophrenia
37.
Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances
Controlled release dosage forms are described herein. The controlled release formulations described herein provide prolonged delivery of high dose drugs that are highly water soluble and highly hygroscopic. In specific embodiments, controlled release dosage forms for delivery of a drug selected from GHB and pharmaceutically acceptable salts, hydrates, tautomers, solvates and complexes of GHB. The controlled release dosage forms described herein may incorporate both controlled release and immediate release formulations in a single unit dosage form.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparation for the treatment of narcolepsy;
pharmaceutical preparations acting on the central nervous
system; pharmaceutical preparations for use in the treatment
and/or management of sleep disorders, neurological
disorders.
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing support services in the nature of medical information to physicians and patients regarding the recognition, screening, and diagnosis of sleep apnea and excessive sleepiness; medical information; providing medical information; providing online medical information via the Internet and social media
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing support services in the nature of medical information to physicians and patients regarding the recognition, screening, and diagnosis of sleep apnea and excessive sleepiness; medical information; providing medical information; providing online medical information via the Internet and social media
36 - Services financiers, assurances et affaires immobilières
Produits et services
Providing information in insurance matters; insurance consultation; health care insurance consultation in the nature of providing assistance to others in obtaining insurance reimbursement of medical expenses for pharmaceuticals
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing healthcare information, medical information, and pharmaceutical information online, by telephone, and through distribution of printed healthcare materials to patients, physicians, medical office staff, pharmaceutical prescribers, and pharmacies regarding patient access to and reimbursement for pharmaceuticals and safe and appropriate use and distribution of pharmaceuticals
44.
JAZZ CARES MAKING A DIFFERENCE IN PATIENTS' LIVES, ONE PATIENT AT A TIME
36 - Services financiers, assurances et affaires immobilières
Produits et services
Providing information in insurance matters; insurance consultation; health care insurance consultation in the nature of providing assistance to others in obtaining insurance reimbursement of medical expenses for pharmaceuticals
45.
JAZZ CARES MAKING A DIFFERENCE IN PATIENTS' LIVES, ONE PATIENT AT A TIME
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing healthcare information, medical information, and pharmaceutical information online, by telephone, and through distribution of printed healthcare materials to patients, physicians, medical office staff, pharmaceutical prescribers, and pharmacies regarding patient access to and reimbursement for pharmaceuticals and safe and appropriate use and distribution of pharmaceuticals
46.
Devices and methods for facilitating and controlling use of a medication
A device includes a reservoir configured to store a drug formulation including at least one abuse-preventing additive. The device further includes means configured to remove the at least one abuse-preventing additive. The device further includes means configured to prevent access to the drug formulation.
A61K 31/19 - Acides carboxyliques, p. ex. acide valproïque
A61K 31/191 - Acides acycliques ayant plusieurs groupes hydroxyle, p. ex. acide gluconique
A61J 3/00 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration
A61K 31/485 - Dérivés du morphinane, p. ex. morphine, codéine
A61K 31/22 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p. ex. pravastatine
A61J 7/00 - Dispositifs pour administrer les médicaments par voie buccale, p. ex. cuillèresDispositifs pour compter les pilulesDispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing support services in the nature of medical information to physicians and patients regarding the recognition, screening, and diagnosis of narcolepsy and excessive sleepiness; medical information; providing medical information; providing online medical information via the Internet and social media
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing support services in the nature of medical information to physicians and patients regarding the recognition, screening, and diagnosis of narcolepsy and excessive sleepiness; medical information; providing medical information; providing online medical information via the Internet and social media
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
House mark for a full line of pharmaceutical products;
pharmaceutical products for the prevention and treatment of
cancer; pharmaceutical preparations and substances for the
treatment of psychiatric diseases and disorders;
pharmaceutical preparations acting on the central nervous
system; pain relief medication; pharmaceutical preparations
for use in the treatment and/or management of sleep
disorders; pharmaceutical preparations for the treatment of
narcolepsy; and pharmaceutical preparations for the
treatment of schizophrenia; pharmaceutical preparations for
use in oncology and hematology.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Applications in the field of neurology diseases, namely application for portable devices players, namely for mobile telephones, smartphones, tablets, computers, e-readers (downloadable).
55.
Devices and methods for facilitating and controlling use of a medication
A method for providing a drug includes providing an inactive form of a drug. The method also includes chemically converting the inactive form of the drug to an active form to provide a drug formulation usable by a patient in need thereof, including using a device configured to remove an abuse-preventing additive from the inactive form of the drug. The method also includes dispensing the drug formulation to the patient in need thereof.
A61K 31/191 - Acides acycliques ayant plusieurs groupes hydroxyle, p. ex. acide gluconique
A61J 7/00 - Dispositifs pour administrer les médicaments par voie buccale, p. ex. cuillèresDispositifs pour compter les pilulesDispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments
A61K 31/22 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p. ex. pravastatine
A61J 3/00 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
House mark for a line of pharmaceuticals for the treatment and prevention of cancer, psychiatric diseases and disorders, central nervous system conditions, pain, sleep disorders, narcolepsy, schizophrenia, and for use in oncology and hematology; pharmaceutical products for the prevention and treatment of cancer; pharmaceutical preparations and substances for the treatment of psychiatric diseases and disorders; Pharmaceutical preparations acting on the central nervous system; pain relief medication; pharmaceutical preparations for use in the treatment and/or management of sleep disorders; pharmaceutical preparations for the treatment of narcolepsy; pharmaceutical preparations for the treatment of schizophrenia; pharmaceutical preparations for use in oncology and hematology
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
House mark for a line of pharmaceuticals for the treatment and prevention of cancer, psychiatric diseases and disorders, central nervous system conditions, pain, sleep disorders, narcolepsy, schizophrenia, and for use in oncology and hematology; pharmaceutical products for the prevention and treatment of cancer; pharmaceutical preparations and substances for the treatment of psychiatric diseases and disorders; Pharmaceutical preparations acting on the central nervous system; pain relief medication; pharmaceutical preparations for use in the treatment and/or management of sleep disorders; pharmaceutical preparations for the treatment of narcolepsy; pharmaceutical preparations for the treatment of schizophrenia; pharmaceutical preparations for use in oncology and hematology
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
House mark for a line of pharmaceuticals for the treatment and prevention of cancer, psychiatric diseases and disorders, central nervous system conditions, pain, sleep disorders, narcolepsy, schizophrenia, and for use in oncology and hematology; pharmaceutical products for the prevention and treatment of cancer; pharmaceutical preparations and substances for the treatment of psychiatric diseases and disorders; Pharmaceutical preparations acting on the central nervous system; pain relief medication; pharmaceutical preparations for use in the treatment and/or management of sleep disorders; pharmaceutical preparations for the treatment of narcolepsy; pharmaceutical preparations for the treatment of schizophrenia; pharmaceutical preparations for use in oncology and hematology
59.
Immediate release formulations and dosage forms of gamma-hydroxybutyrate
The present invention provides a solid immediate release dosage form adapted for oral administration of GHB. The solid immediate release dosage form includes an immediate release formulation comprising a relatively high weight-percentage of GHB with a bioavailability similar to that of a liquid GHB dosage form.
Provided herein are pharmaceutical compositions and formulations comprising mixed salts of gamma-hydroxybutyrate (GHB). Also provided herein are methods of making the pharmaceutical compositions and formulations, and methods of their use for the treatment of sleep disorders such as apnea, sleep time disturbances, narcolepsy, cataplexy, sleep paralysis, hypnagogic hallucination, sleep arousal, insomnia, and nocturnal myoclonus.
A61K 31/19 - Acides carboxyliques, p. ex. acide valproïque
A61K 31/554 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p. ex. clothiapine, diltiazem
61.
GAMMA-HYDROXYBUTYRATE COMPOSITIONS AND THEIR USE FOR THE TREATMENT OF DISORDERS
Provided herein are pharmaceutical compositions and formulations comprising mixed salts of gamma-hydroxybutyrate (GHB). Also provided herein are methods of making the pharmaceutical compositions and formulations, and methods of their use for the treatment of sleep disorders such as apnea., sleep time disturbances, narcolepsy, cataplexy, sleep paralysis, hypnagogic hallucination, sleep arousal, insomnia, and nocturnal myoclonus.
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing support services in the nature of medical information to physicians and patients regarding the recognition, screening, and diagnosis of narcolepsy and excessive sleepiness; medical information; providing medical information
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Providing support services in the nature of medical information to physicians and patients regarding the recognition, screening, and diagnosis of narcolepsy and excessive sleepiness; medical information; providing medical information
70.
IMMEDIATE RELEASE FORMULATIONS AND DOSAGE FORMS OF GAMMA-HYDROXYBUTYRATE
The present invention provides a solid immediate release dosage form adapted for oral administration of GHB. The solid immediate release dosage form includes an immediate release formulation comprising a relatively high weight-percentage of GHB with a bioavailability similar to that of a liquid GHB dosage form.
Controlled release dosage forms are described herein. The controlled release formulations described herein provide prolonged delivery of high dose drugs that are highly water soluble and highly hygroscopic. In specific embodiments, controlled release dosage forms for delivery of a drug selected from GHB and pharmaceutically acceptable salts, hydrates, tautomers, solvates and complexes of GHB. The controlled release dosage forms described herein may incorporate both controlled release and immediate release formulations in a single unit dosage form.
The present invention provides a solid immediate release dosage form adapted for oral administration of GHB. The solid immediate release dosage form includes an immediate release formulation comprising a relatively high weight-percentage of GHB with a bioavailability similar to that of a liquid GHB dosage form.
The present invention provides a pharmaceutical composition, presented as a solid unit dosage form adapted for oral administration of sodium oxybate. The preferred unit dosage form is a tablet comprising a relatively high weight-percentage of sodium oxybate, in combination with a relatively small weight-percentage of total excipients. This permits the tablets to contain/deliver a pharmaceutically effective amount, e.g., about 0.5-1.5 g of sodium oxybate in each tablet with a delivery profile similar to that of the liquid form. The tablets are bioequivalent to the liquid form.
The present invention provides a pharmaceutical composition, presented as a solid unit dosage form adapted for oral administration of sodium oxybate. The preferred unit dosage form is a tablet comprising a relatively high weight-percentage of sodium oxybate, in combination with a relatively small weight-percentage of total excipients. This permits the tablets to contain/deliver a pharmaceutically effective amount, e.g., about 0.5-1.5 g of sodium oxybate in each tablet with a delivery profile similar to that of the liquid form. The tablets are bioequivalent to the liquid form.
The present invention includes benzodiazepine compositions formulated for intranasal administration, comprising a binary solvent system comprising a first solvent in which the benzodiazepine is soluble, the first solvent capable of penetrating nasal mucosal tissue, and a second solvent in which the benzodiazepine in less soluble. The compositions of the present invention may be used to treat a variety of disorders including, but not limited to, panic attacks, muscle spasms, anxiety, and seizures. In one aspect, the present invention relates to a fast-acting, clonazepam composition for transnasal administration that can be used for the treatment of seizure clusters.
The present invention includes benzodiazepine compositions formulated for intranasal administration, comprising a binary solvent system comprising a first solvent in which the benzodiazepine is soluble, the first solvent capable of penetrating nasal mucosal tissue, and a second solvent in which the benzodiazepine in less soluble. The compositions of the present invention may be used to treat a variety of disorders including, but not limited to, panic attacks, muscle spasms, anxiety, and seizures. In one aspect, the present invention relates to a fast-acting, clonazepam composition for transnasal administration that can be used for the treatment of seizure clusters.
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Providing telephone support services to physicians regarding the safe and appropriate use and distribution of medications used to treat sleep disorders; providing medical information via telephone and in the form of written educational materials to physicians in connection with the safe and appropriate use and distribution of medication for the treatment of sleep disorders.
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Providing telephone support services to physicians regarding the safe and appropriate use and distribution of medications used to treat sleep disorders; providing medical information via telephone and in the form of written educational materials to physicians in connection with the safe and appropriate use and distribution of medication for the treatment of sleep disorders.
Marketing consultation in the field of medical and pharmaceutical products; and arranging and conducting trade show exhibitions in the fields of medicine and pharmaceuticals
Marketing consultation in the field of medical and pharmaceutical products; and arranging and conducting trade show exhibitions in the fields of medicine and pharmaceuticals
Marketing consultation in the field of medical and pharmaceutical products; and arranging and conducting trade show exhibitions in the fields of medicine and pharmaceuticals
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Educational services, namely, arranging and conducting medical educational conferences, exhibitions, training courses, and seminars in the fields of medicine, pharmaceuticals, and medical science; and providing continuing medical education courses
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Educational services, namely, arranging and conducting medical educational conferences, exhibitions, training courses, and seminars in the fields of medicine, pharmaceuticals, and medical science; and providing continuing medical education courses
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Educational services, namely, arranging and conducting medical educational conferences, exhibitions, training courses, and seminars in the fields of medicine, pharmaceuticals, and medical science; and providing continuing medical education courses
Printed materials, namely, pamphlets, brochures, booklets, and manuals, concerning medicine; printed materials, namely, pamphlets, brochures, and booklets, concerning the medical and pharmaceutical fields; monographs in the field of medicine; printed instructional, educational, and teaching materials in the field of medicine; [ note pads; pens; and folders ]
Printed materials, namely, pamphlets, brochures, booklets, and manuals, concerning medicine; printed materials, namely, pamphlets, brochures, and booklets, concerning the medical and pharmaceutical fields; monographs in the field of medicine; printed instructional, educational, and teaching materials in the field of medicine [ ; note pads; pens; and folders ]
Printed materials, namely, pamphlets, brochures, booklets, and manuals, concerning medicine; printed materials, namely, pamphlets, brochures, and booklets, concerning the medical and pharmaceutical fields; monographs in the field of medicine; printed instructional, educational, and teaching materials in the field of medicine [ ; note pads; pens; and folders ]
36 - Services financiers, assurances et affaires immobilières
Produits et services
Providing information in insurance matters; insurance consultation; health care insurance consultation in the nature of providing assistance to others in obtaining insurance reimbursement of medical expenses for pharmaceuticals
Providing on-line communications links which transfer the website user to other local and global web pages; and on-line document delivery via a global computer network
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Providing customized on-line web pages featuring user-defined information, which includes on-line web links to other web sites; providing information at the specific request of end-users by means of telephone or global computer networks; scientific research and development; pharmaceutical drug development services; pharmaceutical research and development; research and development for new products for others
Providing on-line communications links which transfer the website user to other local and global web pages; and on-line document delivery via a global computer network
36 - Services financiers, assurances et affaires immobilières
Produits et services
Providing information in insurance matters; insurance consultation; health care insurance consultation in the nature of providing assistance to others in obtaining insurance reimbursement of medical expenses for pharmaceuticals
36 - Services financiers, assurances et affaires immobilières
Produits et services
Providing information in insurance matters; insurance consultation; health care insurance consultation in the nature of providing assistance to others in obtaining insurance reimbursement of medical expenses for pharmaceuticals
Providing on-line communications links which transfer the website user to other local and global web pages; and on-line document delivery via a global computer network
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Providing customized on-line web pages featuring user-defined information, which includes on-line web links to other web sites; providing information at the specific request of end-users by means of telephone or global computer networks; scientific research and development; pharmaceutical drug development services; pharmaceutical research and development
