Abrégé

Method for the solid-phase synthesis of a peptide comprising coupling cycles of amino acid building blocks to an amino acid chain, wherein at least one of said amino acid building blocks comprises one or more histidine residues with an unprotected side-chain, and at least one coupling cycle comprises using a coupling reagent selected from the group consisting of N-tert-Butyl-N'-ethylcarbodiimide and N-tert-Butyl-N'- isopropylcarbodiimide.

Classes IPC  ?

• C07K 1/06 - Procédés généraux de préparation de peptides utilisant des groupes protecteurs ou des agents d'activation
• C07K 1/10 - Procédés généraux de préparation de peptides utilisant des agents de couplage

Abrégé

Ankle mobilisation device (100) comprising: a frame (10, 10', 11, 12, 12', 13, 16) comprising a retention system (13, 16) of a leg of a user of the device (100), configured for preventing and/ or reducing movement of the leg (200); a calcaneal support (31', 31", 32, 33, 34, 35, 36", 36", 37) configured for accommodating an ankle of a user, said ankle being provided with a dorsiflexion/ plantarflexion axis of rotation (x); means for actuating (21, 22, 23, 24', 25, 26, 40, 41, 42, 43, 44, 40', 41', 42') comprising a motor (25) configured for generating a rotation about an axis of actuation and a coupling (26, 40, 41, 42, 43, 44, 40', 41', 42') placed between the motor (25) and the calcaneal support (31', 31", 32, 33, 34, 35, 36', 36", 37); the calcaneal support (31', 31", 32, 33, 34, 35, 36', 36", 37), in turn, comprising a rigid casing (31', 31") and a deformable filler (32) positioned within the rigid casing (31', 31") and such that it can be shaped to the shape of a user's calcaneus and the coupling (26, 40, 41, 42, 43, 44, 40', 41', 42') having at least one degree of freedom translational in the direction of the axis of actuation, and no degree of freedom in torsion, so as to compensate for misalignments between the axis of actuation and the axis of rotation (x).

Classes IPC  ?

• A61H 1/02 - Appareils d'exercice extenseurs ou de ployage

Abrégé

YarrowiaYarrowiaYarrowiaYarrowia in the production of dairy products.

Classes IPC  ?

• A23C 19/032 - Fabrication du caillé pour fromage caractérisée par l'emploi de micro-organismes spécifiques, ou d'enzymes d'origine microbienne
• A23C 19/068 - Types particuliers de fromages
• C12N 1/16 - LevuresLeurs milieux de culture
• C12R 1/645 - Champignons

Abrégé

The present invention relates to a synthetic peptide comprising the following elements from the N-terminus to the C-terminus: a) a first cell-penetrating peptide or functional fragments or derivatives, or biologically active variants thereof and b) a second peptide with agonist activity of OR1 and OR2 receptors or functional fragments or derivatives, or biologically active variants thereof.

Classes IPC  ?

• C07K 14/575 - Hormones
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 38/00 - Préparations médicinales contenant des peptides
• C07K 14/16 - HIV-1
• C12N 15/62 - Séquences d'ADN codant pour des protéines de fusion
• C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales

Abrégé

A semi-dry method of manufacturing an electrode (E) is disclosed comprising: a) providing a conductive metal substrate, preferably a copper or aluminium laminate; b) providing an electrode formulation (EF) in the form of a cohesive solid material, 5 the electrode formulation (EF) comprising: F1) at least the following functional ingredients: an electrode active material for anode or cathode, a binder and a plasticizer, and F2) a solvent in an amount equal to or lower than 25% by weight based on the total weight of the functional ingredients; 0 c) coating at least a first face of the conductive metal substrate with the electrode formulation (EF); and d) compressing the coated conductive metal substrate. An electrode formulation (EF), a method of manufacturing the electrode formulation (EF) in the form of a self-supporting film, an electrode composition 5 and an energy storage device comprising the electrode composition are also disclosed.

Classes IPC  ?

• H01M 4/04 - Procédés de fabrication en général
• H01M 4/139 - Procédés de fabrication

Abrégé

EE2 of a power cable (10) comprising an internal cylindrical electrode (11), an external cylindrical electrode (12), and an insulating layer (13) of electric insulating material (MI) interposed between said electrodes (11, 12), starting from breakdown tests with alternating voltage on a plurality of thin circular flat samples (100) of insulating material (MI).

Classes IPC  ?

• G01R 31/12 - Test de la rigidité diélectrique ou de la tension disruptive
• G01R 31/20 - Préparation des articles ou des spécimens pour faciliter le test

Abrégé

The present invention relates to a method for the ex vivo molecular diagnosis of gastrointestinal stromal tumors, comprising the steps of: providing at least one isolated tissue sample comprising at least one nucleic acid and the subsequent extraction of the at least one nucleic acid. The method according to the present invention further comprises a step of quantifying the at least one previously isolated nucleic acid. Furthermore, the method according to the present invention comprises preparing at least one amplicon library of said previously isolated nucleic acid, which comprises sequences obtained from the FGFR1, NF1, SDHA, SDHB, SDHC and SDHD genes. This step is followed by the step of purifying the at least one amplicon library and the step of simultaneously sequencing the amplicons themselves. The present invention also relates to a multi-gene panel for ex vivo molecular diagnosis of gastrointestinal stromal tumors and a kit comprising such a panel.

Classes IPC  ?

• C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer

Abrégé

An apparatus for induction heating of ferromagnetic materials in which a single electromagnet is used for simultaneous generation of AC and DC fields.

Classes IPC  ?

• H05B 6/10 - Appareils de chauffage par induction, autres que des fours, pour des applications spécifiques
• C21D 1/42 - Chauffage par induction
• H05B 6/06 - Commande, p. ex. de la température, de la puissance

Abrégé

Apparatuses, systems, and methods for implementing temporal lockstep for error detection utilizing a single processor core are provided. For example, a processor core includes a pipeline with an instruction fetch circuit and an instruction decode and execute circuit. The instruction decode and execute circuit comprises a controller including a finite state machine with a plurality of states to control the processor core. A voting circuit is provided to vote on a control signal to control the finite state machine for transitioning from a current state to a next state. The processor core, based at least on the plurality of states of the finite state machine, is configured to: execute the first dummy instruction to generate a first dummy result; store the first dummy result in a first dummy buffer; execute the first real instruction to generate a first real result; compare the results to identify an error.

Classes IPC  ?

• G01R 31/317 - Tests de circuits numériques
• G06F 9/30 - Dispositions pour exécuter des instructions machines, p. ex. décodage d'instructions
• G06F 9/38 - Exécution simultanée d'instructions, p. ex. pipeline ou lecture en mémoire

Abrégé

The present invention generally refers to the technical field concerning processes related to the production of fat acids. Specifically, the present invention relates to a process for preparing a compound of Formula (I).

Classes IPC  ?

• C25B 3/07 - Composés contenant au moins un atome d’oxygène
• C25B 3/26 - Réduction du dioxyde de carbone
• C25B 3/29 - Réactions de couplage
• C25B 9/17 - Cellules comprenant des électrodes fixes de dimensions stablesAssemblages de leurs éléments de structure
• C25B 11/043 - Carbone, p. ex. diamant ou graphène
• C25B 15/08 - Alimentation ou vidange des réactifs ou des électrolytesRégénération des électrolytes

Abrégé

The present invention relates to compounds of formula (Ia) and their pharmaceutical composition These compounds are for the use in the treatment of a disease or disorder selected from the group consisting of fungal infections, bacterial infections, neurological and neurodevelopmental disorders and cancer.

Classes IPC  ?

• C07D 209/14 - Radicaux substitués par des atomes d'azote ne faisant pas partie d'un radical nitro
• C07D 209/40 - Atomes d'azote ne faisant pas partie d'un radical nitro, p. ex. semicarbazone d'isatine
• C07D 471/04 - Systèmes condensés en ortho
• A61P 31/00 - Agents anti-infectieux, c.-à-d. antibiotiques, antiseptiques, chimiothérapeutiques
• A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline

Abrégé

The present invention relates to a method (100) implemented by computer for defining a geometry and an arrangement of a plurality of electrodes (El-En) for a piezoelectric device (1) installable on an installation area (Z) of a surface (F), said method (100) comprising: obtaining (101) one or more images (Sl-Sn) of the spatial distribution of the wave field of an ultrasonic wave on said installation area (Z), wherein said ultrasonic wave originates from a point (P) on said surface (F) located at a distance (D) from said installation area (Z); comparing (102) the wave field value of the respective pixels of said one or more images (Sl-Sn) with an upper threshold (Thmax) or a lower threshold (Thmin); and defining (103) said geometry and said arrangement for each of said plurality of electrodes (El-En) of said piezoelectric device (1) based on said comparison.

Classes IPC  ?

• G01N 29/26 - Dispositions pour l'orientation ou le balayage

Abrégé

A biotechnological process for producing PHA is described, comprising the steps of: subjecting an initial mixture containing a mixed bacterial mass to a biological selection process, so as to obtain a first intermediate mixture containing mainly selected bacteria able to store a carbonaceous source (for example VFA) in the form of PHA; introducing said first intermediate mixture in a tank reactor (120, 215) operating under anoxic con-ditions; introducing in said tank reactor (120, 215) also an aqueous nutrient solution, containing both the carbonaceous source (for example VFA) and nutrients, so as to ob-tain within said tank reactor (120, 215) a second intermediate mixture comprising PHA-containing bacteria; treating said second intermediate mixture with a solid-liquid separa-tion apparatus (125, 220), for example a vertical axis centrifuge, a decanter centrifuge or any other device adapted to execute a centrifugal separation of the second interme-diate mixture, so as to obtain a final mixture having a higher solids concentration with respect to that of the second intermediate mixture; subjecting the final mixture to a PHA extraction process.

Classes IPC  ?

• C12P 7/625 - Polyesters d'acides hydroxycarboxyliques
• C12P 39/00 - Procédés faisant intervenir simultanément des micro-organismes de différents genres dans le même procédé
• C02F 3/28 - Procédés de digestion anaérobies
• C02F 3/34 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout caractérisé par les micro-organismes utilisés

Abrégé

The present invention relates to a device for locating (100) pituitary fossa in veterinary medicine and a method for locating the pituitary fossa in veterinary medicine by means of such a device.

Classes IPC  ?

• A61D 1/00 - Instruments de chirurgie vétérinaire
• A61B 17/17 - Dispositifs de guidage pour les forets

Abrégé

The invention is directed to a multifunctional system bearing a ligand capable of recognizing tumor cells or tumor-associated or inflammation-associated component and linked to a metal nanoparticle. More specifically, the multifunctional system of the invention comprises a nucleotide aptamer or a variant thereof that binds to the alpha 5 subunit of integrin and a metal nanoparticle, wherein said aptamer optionally comprises at least one modification capable of enhancing nuclease resistance thus providing a molecule with high stability for example in human urine.

Classes IPC  ?

• C12N 15/115 - Aptamères, c.-à-d. acides nucléiques liant spécifiquement une molécule cible avec une haute affinité sans s'y hybrider
• G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques

Abrégé

The present invention relates to a method allowing a rapid and sensitive genome molecular detection, by the detection of nucleic acids thereof. Specifically, the method combines the cooperative hybridization process of a macromolecular genetic target on the electrode surface derivatized with an electrochemiluminescence (ECL)-based ultrasensitive detection. The method allows to directly detect a target genome without any amplification. Therefore, the method of the invention can be considered as an amplification-free approach, in particular a PCR-free approach.

Classes IPC  ?

• C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
• C12Q 1/6825 - Détecteurs faisant intervenir la détection d’acides nucléiques

Abrégé

The present invention relates to a process for detecting an analyte in an isolated sample, wherein said analyte is a target nucleic acid, comprising the steps of: supplying a sample comprising at least one nucleic acid; heat-treating said sample; contacting the heat-treated sample with at least two single-stranded nucleic acid probes in which each of said at least two single-stranded nucleic acid probes is complementary to a corresponding portion of said target nucleic acid; adding an active luminophore; determining a luminescence signal generated by the active luminophore.

Classes IPC  ?

• C12Q 1/6825 - Détecteurs faisant intervenir la détection d’acides nucléiques
• C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages

Abrégé

A cosmetic solid composition comprising: a. phospholipid nanoparticles comprising a product obtained by extraction of a vegetal matrix with a hydroalcoholic mixture or with biosolvents; and b. a natural film-forming polymer preferably selected from hyaluronic acid and its salts, sodium alginate, carrageenan, Arabic gum, xanthan gum, pectin or mixtures thereof; and optionally c. a plasticizing agent, preferably glycerin; wherein said phospholipid nanoparticles are preferably ethosomes, phytosomes, liposomes and wherein said composition can be reconstituted into a fluid cosmetic by the addition of water at the time of application on the skin, wherein said composition is anhydrous, wherein said composition does not comprise preservatives, wherein said composition is in the form of a film.

Classes IPC  ?

• A61K 8/02 - Cosmétiques ou préparations similaires pour la toilette caractérisés par une forme physique particulière
• A61K 8/14 - Liposomes
• A61K 8/34 - Alcools
• A61K 8/55 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant du phosphore
• A61K 8/73 - Polysaccharides
• A61K 8/92 - Huiles, graisses ou ciresLeurs dérivés, p. ex. produits d'hydrogénation
• A61K 8/9789 - Magnoliopsida [dicotylédones]
• A61K 8/9794 - Liliopsida [monocotylédones]
• A61Q 19/00 - Préparations pour les soins de la peau

Abrégé

A simulated blood composition comprises a gelatinizable component and a gelatinizing component, said gelatinizable component comprising an alginic acid salt and a red colouring agent, and said gelatinizing component comprising a calcium salt. The gelatinizable component and the gelatinizing component are arranged for being brought into contact with each other at the time of use, so as to simulate the formation of a blood clot. The simulated blood composition can be made in the form of a kit, comprising the gelatinizable component and the gelatinizing component in solid or liquid form. The simulated blood composition can be used in combination with an anatomical simulator for veterinary medicine or human medicine, for example for simulating a venipuncture or a bleeding from a wound.

Classes IPC  ?

• G09B 23/28 - Modèles à usage scientifique, médical ou mathématique, p. ex. dispositif en vraie grandeur pour la démonstration pour la médecine

Abrégé

A process for the activation of a vanadium/phosphorus mixed oxide catalyst (“VPO” catalyst) precursor, whereby the precursor is transformed into the corresponding active catalyst suitable for use in the production of maleic anhydride by partial oxidation of n-butane.

Classes IPC  ?

• B01J 23/22 - Vanadium
• B01J 37/08 - Traitement thermique
• B01J 37/10 - Traitement thermique en présence d'eau, p. ex. de vapeur d'eau
• B01J 37/12 - Oxydation
• C07C 51/215 - Préparation d'acides carboxyliques, de leurs sels, halogénures ou anhydrides par oxydation avec l'oxygène moléculaire de groupes hydrocarbyle saturés

Abrégé

A process for the production of mixtures including compounds having a number of carbon atoms ≥6, usable as jet fuel or as jet fuel precursors starting from one or more alcohols having from 2 (C2) to 4 (C4) carbon atoms, wherein the one or more alcohols are introduced into a continuously operating fixed bed catalytic reactor, in an amount from 1 to 100 mol %, in the vapour phase and at a temperature ranging from 200 to 450° C., the catalyst includes metallic copper on a zirconia-based support, the metallic copper is in a percentage by weight ranging from 0.5% to 25% of the total weight of the catalyst. A plant for the production of a mixture including compounds having a number of carbon atoms ≥6, usable as a jet fuel or jet fuel precursor, starting from one or more alcohols having from 2 to 4 carbon atoms.

Classes IPC  ?

• C10L 1/02 - Combustibles carbonés liquides à base essentielle de composants formés uniquement de carbone, d'hydrogène et d'oxygène
• B01J 21/06 - Silicium, titane, zirconium ou hafniumLeurs oxydes ou hydroxydes
• B01J 23/10 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe des terres rares
• B01J 23/72 - Cuivre
• B01J 35/54 - Bâtonnets ou plaquettes
• B01J 37/02 - Imprégnation, revêtement ou précipitation
• B01J 37/08 - Traitement thermique

Abrégé

A synthesis process comprising a step of reacting HMF to obtain BHMF under hydrogen pressure and wherein HMF is contacted with a catalyst mixture, said catalyst mixture comprising a metal catalyst of a transition metal of Group 8 or a salt of said catalyst and optionally an organic solvent.

Classes IPC  ?

• B01J 31/22 - Complexes organiques
• B01J 31/20 - Carbonyles
• C07D 307/44 - Alcool furfurylique
• C07F 17/02 - Metallocènes de métaux des groupes 8, 9 ou 10 du tableau périodique
• B01J 31/02 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques

Abrégé

Use of a non-woven fabric comprising polylactic acid fibers for inoculation of to be mycorrhized plants.

Classes IPC  ?

• A01G 29/00 - Dispositifs pour l'alimentation des racinesInjection d'engrais dans les racines

Abrégé

An electroadhesive device (1) configured for adhering to a surface of an object to be retained, said device (1) comprising a first insulating substrate (2) having a first relative electric permittivity value, a second insulating substrate (3) having a second relative electric permittivity value and having a surface (4) suitable for interfacing with the surface of the object (8) to be retained, at least one pair of electrodes (5) arranged between the first and second substrates (2,3), having a first resistivity value, and configured for generating a voltage difference in the substrate (3), wherein said voltage difference generates an electric field propagating to the surface (4) and interacting with the electric charges of the object (8), so as to generate, between the device (1) and the object (8), an electrostatic adhesion force capable of maintaining a current position of the device (1) relative to the object (8), a third substrate (6) arranged between the first and second insulating substrates (2,3) and in contact with the at least one pair of electrodes (5), so as to reduce the electric field concentration in the zones of electric field discontinuity on the interface surfaces between the at least one pair of electrodes (5) and the insulating substrates (2,3), said third substrate comprising a semi conductive material having a second resistivity value not smaller than the first resistivity value of the at least one pair of electrodes (5), or an insulating material having a third relative electric permittivity value.

Classes IPC  ?

• H02N 13/00 - Embrayages ou dispositifs de maintien utilisant l'attraction électrostatique, p. ex. utilisant l'effet Johnson-Rahbek
• H01G 7/02 - Électrets, c.-à-d. ayant un diélectrique polarisé en permanence
• H01L 21/683 - Appareils spécialement adaptés pour la manipulation des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide pendant leur fabrication ou leur traitementAppareils spécialement adaptés pour la manipulation des plaquettes pendant la fabrication ou le traitement des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide ou de leurs composants pour le maintien ou la préhension

Abrégé

Three-dimensional printer (10) for creating a printed object (100) integrating respective discrete guide means (101), said three-dimensional printer (10) having a load-bearing structure (11) comprising both an adjustable frame (13), on which at least one printing head (12) is mounted sliding, and also one or more support and movement units (20) associated with the frame (13) and defining corresponding rest points for the load-bearing structure (11).

Classes IPC  ?

• B29C 64/232 - Moyens d’entraînement pour un mouvement le long de l'axe orthogonal au plan d’une couche
• B29C 64/40 - Structures de support des objets en 3D pendant la fabrication, lesdites structures devant être sacrifiées après réalisation de la fabrication
• B33Y 30/00 - Appareils pour la fabrication additiveLeurs parties constitutives ou accessoires à cet effet
• B22F 10/47 - Structures destinées à soutenir des pièces ou des articles pendant la fabrication et retirées par la suite caractérisées par des caractéristiques structurelles
• B22F 12/00 - Appareils ou dispositifs spécialement adaptés à la fabrication additiveMoyens auxiliaires pour la fabrication additiveCombinaisons d’appareils ou de dispositifs pour la fabrication additive avec d’autres appareils ou dispositifs de traitement ou de fabrication
• E04G 21/04 - Dispositifs pour transporter et distribuer en même temps

Abrégé

A device for the placement of organic tissue, in particular endocrine tissue, includes a hollow tubular base element configured to house in a seat at least one portion of the organic tissue, a pushing element which inserted on the inside of the base element and coupled to it in a sliding manner; wherein the base element is configured to at least partially penetrate a target tissue. The base element further includes a first opening, which is arranged in a distal zone towards a first end and is configured to let out and, hence, position the organic tissue in the target tissue through the action of the pushing element.

Classes IPC  ?

• A61B 17/34 - TrocartsAiguilles à ponction
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
• A61B 17/425 - Instruments ou procédés de gynécologie ou d'obstétrique pour la reproduction ou la fertilisation

Abrégé

The present invention concerns a garment (5) made of fabric, wearable by a user (U), wherein said garment (5) comprises a transponder device (3), having a transceiver antenna (31 ) and a proximity unit (32), connected to said antenna (31 ), and configured to detect a proximity signal emitted by an emitter device (2), received via said antenna (31 ), and transmit a distancing signal to communicate the distance (d) from said emitter device (2), characterized in that the electronic circuits that constitute said antenna (31 ) and said proximity unit (32) are integrated into the fabric of said garment (5). The present invention also concerns a method for integrating the circuit of a transponder device (3) and a safety and control system (1 ).

Classes IPC  ?

• A41D 1/00 - Vêtements

Abrégé

Motorized upper prosthetic limb (A) comprising a hand (1) with fingers (5), a first elastically flexurally deformable element onboard each finger, wherein the first element is elastically flexurally deformable in a transverse direction (X1, X2, X3, Z1) with respect to the extension direction of each finger, a forearm (2) comprising a connection interface (4) that can be releasably attached to a user's body, and a second elastically flexurally deformable element in a transverse direction (X4, Z2) relative to the extension direction of the forearm (2), with the second elastically deformable element being interposed between the hand and the forearm to movably connect the hand to the forearm. The prosthetic limb also includes a plurality of electromechanical rotary actuators arranged on the forearm (2), and a plurality of strings, each having a first end connected to an actuator and a second end, longitudinally opposite to the first, rigidly and individually connected to one of the first or second elastically deformable elements.

Classes IPC  ?

• A61F 2/54 - Bras ou mains artificiels ou leurs parties
• A61F 2/58 - CoudesPoignets
• A61F 2/70 - Moyens d'actionnement ou de commande électriques
• A61F 2/74 - Moyens d'actionnement ou de commande à fluide
• B25J 9/00 - Manipulateurs à commande programmée
• B25J 15/00 - Têtes de préhension

Abrégé

A prosthetic implant of the ESR (energy-storing-and-returning) type, includes an upper assembly and a lower assembly, configured to define a foot and including a lower blade, an intermediate blade and an upper blade. The upper blade, the lower blade and the intermediate blade are fastened stably to each other at at least one connecting point located in the front region or in the middle region of the foot. An articulated joint is interposed between the lower assembly and the upper one to allow relative motion between them. The implant includes a connector having a first end that is connected to the upper assembly and a second end that is connected to the intermediate blade of the lower assembly. At least one between the first and the second end of the connector is movable along a movement direction to vary the force applied on the intermediate blade of the lower assembly.

Classes IPC  ?

• A61F 2/66 - PiedsArticulations de la cheville
• A61F 2/70 - Moyens d'actionnement ou de commande électriques

Abrégé

The present invention is related to a system and method for peptide and oligonucleotide ("tide") manufacture, making use of reactor with discriminating membrane technology to separate out byproducts and excess reagents from the reaction mixture. The discriminating membrane technology is based on the application of a membrane which is configured to act as a solid phase extraction membrane between a reaction chamber and an extraction chamber present within the reactor with an affinity for reagents and by-products present in the reaction chamber.

Classes IPC  ?

• B01J 19/00 - Procédés chimiques, physiques ou physico-chimiques en généralAppareils appropriés
• B01J 19/24 - Réacteurs fixes sans élément interne mobile

Abrégé

An electrochemical microcell comprising: - a chamber adapted to insert an electrode; - at least one microchannel adapted to load a solution of analysis reagent and an analyte solution; wherein the at least one microchannel is in fluid communication with the chamber of the electrochemical microcell, and wherein the chamber is integral with the at least one microchannel; and a method of analysis by means of said electrochemical microcell.

Classes IPC  ?

• G01N 27/28 - Composants de cellules électrolytiques
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes

Abrégé

11N1N1N1N1NN); and - overlaying on each pixel contained in said set of corresponding pixels one and the same image element chosen from a plurality of image elements.

Classes IPC  ?

• G06T 7/593 - Récupération de la profondeur ou de la forme à partir de plusieurs images à partir d’images stéréo

Abrégé

The present invention concerns a motor skills recovery interface device (1 ), comprising: one or more cortical sensors (3; 31, 32,..., 3n), each capable of detecting a respective cortical signal (SE1, SE2,..., SEn) coming from a respective portion of the cerebral cortex (C) of a patient (P); a decoding unit (2), operatively connected to said one or more cortical sensors (3; 31, 32,..., 3n), configured to process each of said cortical signals (SE1, SE2,..., SEn) transmitted by each of called one or more cortical sensors (3; 31, 32,..., 3n); one or more muscle electro¬ stimulators (4), each applicable to a muscle to be stimulated (M); wherein said decoding unit (2) is configured to process one or more actuation signals (SM1, SM2,..., SMn) of said one or more muscle electro-stimulators (4; 41, 42, 4n) on the basis of the cortical signal received by said one or more cortical sensors (31, 32,..., 3n). The present invention also concerns a method of operation of an interface device (1).

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• A61B 5/375 - Électroencéphalographie [EEG] utilisant une rétroaction biologique
• G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur

Abrégé

A method for recognizing, identifying, and locating with millimeter accuracy various electrical, electromechanical, or electronic components installed within an electrical panel, based on the recognition of electrical contacts on the front faces of these components.

Classes IPC  ?

• G06V 10/75 - Organisation de procédés de l’appariement, p. ex. comparaisons simultanées ou séquentielles des caractéristiques d’images ou de vidéosApproches-approximative-fine, p. ex. approches multi-échellesAppariement de motifs d’image ou de vidéoMesures de proximité dans les espaces de caractéristiques utilisant l’analyse de contexteSélection des dictionnaires
• G06V 20/60 - Type d’objets

Abrégé

A computer-implemented method (100) for classifying a lesion as a uterine leiomyoma, UM, or as a uterine leiomyosarcoma, LMS, the method (100) comprising: acquiring (101) at least one Computed Tomography, CT, image of the lesion; obtaining (103) a Region of Interest, ROI, of the lesion within the at least one CT image; calculating (105) one or more radiomic features of said ROI of the lesion; selecting (107), using a plurality of feature se-lection functions, a corresponding plurality of sub-sets of features, wherein each of said plurality of subsets of features comprises one or more selected radiomic features of said one or more radiomic features; applying (109) a corresponding plurality of predictive models which have been trained for classifying a lesion as UM or as LMS to the plurality of subsets of features; and classifying (113) the lesion as UM or as LMS using said plurality of the predictive models.

Classes IPC  ?

• G06T 7/00 - Analyse d'image

Abrégé

A method for estimating a quantity profile of a volume of soil involves placing in the soil volume a bi-dimensional or three-dimensional grid of quantity sensors, each quantity sensor of the grid being identified by a position represented by three-dimensional coordinates with respect to a center of the soil volume, acquiring, in a same instant of time, a quantity value from each quantity sensor, so as to obtain a bi-dimensional or three-dimensional grid of real quantity values, and applying a profiling function to the quantity value grid to obtain a fine grained quantity profile defined by a bi-dimensional or three dimensional extended grid of quantity values. Each value of the extended grid is associated with a position represented by three-dimensional coordinates with respect to the center of the soil volume. The number of elements of the extended grid of quantity values is much greater than the number of quantity sensors.

Classes IPC  ?

• G01N 33/24 - Matériaux de la terre
• G06N 20/00 - Apprentissage automatique

Abrégé

The Limosilactobacillus vaginalis BC17 strain, deposited with number DSM 34059, is usable as an agent for promoting a proliferation of intestinal bifidobacteria in a human subject. A method for promoting the proliferation of intestinal bifidobacteria in a human subject provides for administering to the human subject the Limosilactobacillus vaginalis BC17 strain deposited with number DSM 34059. The strain can be incorporated into a liquid or solid composition that can be administered orally or buccally and the human subject can be a neonate or a suckling. The strain can also be used to prepare compositions that are applicable to the skin of the nipples of a breast-feeding woman.

Classes IPC  ?

• A61K 35/742 - Bactéries sporulées, p. ex. Bacillus coagulans, Bacillus subtilis, clostridium ou Lactobacillus sporogenes
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/06 - OnguentsExcipients pour ceux-ci

Abrégé

Closing apparatus (10) for a door or window opening (101), comprising a structure (11) for attachment to the opening (101), a perimeter frame (12) associated with the attachment structure (11) and mobile with respect thereto between a closed position (Pl) and an open position (P2), and a central panel (13) associated with the perimeter frame (12). The perimeter frame (12) comprises a plurality of resonant ducts (25).

Classes IPC  ?

• E06B 7/06 - Aménagements particuliers ou dispositions en rapport avec les portes ou fenêtres pour assurer la ventilation, p. ex. à travers des doubles fenêtresAménagement de rosaces de ventilation par des volets de ventilation par un seul volet de ventilation
• E06B 7/10 - Aménagements particuliers ou dispositions en rapport avec les portes ou fenêtres pour assurer la ventilation, p. ex. à travers des doubles fenêtresAménagement de rosaces de ventilation par structure particulière des éléments de châssis

Abrégé

Method for controlling a shipment, comprising: arranging a box (10), including: a main body (20), having an inner space (30); a visual detection tool (110) mounted to said main body (20) and configured to capture images portraying one or more objects contained in said inner space (30). The method further comprises performing at least one of a first control operation and a second control operation. The first control operation comprises: while the main body (20) is at least partly open and before shipping of the box (10) is started, capturing first images by said visual detection tool (110); making a first comparison between said first images and first reference data, the first reference data being representative of features expected for the one or more objects (X) contained in the inner space (30); generating a first notification signal (NS1) based on said first comparison. The second control operation comprises: during shipment of the box (10), capturing second images by said visual detection tool (110); making a second comparison between said second images and second reference data, the second reference data being representative of safe conditions of the one or more objects (X) contained in the inner space (30); generating a second notification signal based (NS2) on said second comparison. Also discloses is a system (1) for controlling a shipment.

Classes IPC  ?

• G06Q 10/08 - Logistique, p. ex. entreposage, chargement ou distributionGestion d’inventaires ou de stocks
• G06Q 10/30 - Administration du recyclage ou de l’élimination des produits

Abrégé

The present invention relates to a bacteriophage, or a composition that comprises it, comprising and/or expressing at least one ligand targeting disialoganglioside (GD2) and to its medical or diagnostic uses.

Classes IPC  ?

• C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification
• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• C12N 9/22 - Ribonucléases
• A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
• A61P 35/00 - Agents anticancéreux

Abrégé

A method for evaluating a capacity of a serum to neutralize a virus is disclosed. The method includes preparing a solution comprising at least one cell, a serum and a virus, placing the solution in contact with an organic electrochemical transistor comprising a source, a drain and a gate electrode, wherein the source and drain electrodes are electrically connected by means of a conductive channel, applying a potential difference between the drain and source electrode, applying a plurality of pulses of a potential difference between the gate and source electrode and measuring a respective plurality of values of pulses of current flowing through the channel; calculating a value of an estimation of a response time of the transistor, and comparing the value of the estimated response time with respect to a threshold value and detecting whether the serum has a neutralising capacity against the at least one virus.

Classes IPC  ?

• G01N 27/414 - Transistors à effet de champ sensibles aux ions ou chimiques, c.-à-d. ISFETS ou CHEMFETS

Abrégé

Use of a composite material for the absorption of carbon dioxide and volatile organic compounds in closed-loop or semi-closed-loop breathing systems, wherein the composite material comprises a mineral matrix present in a concentration by weight of between 40% and 95% and a carbonaceous component present in a concentration by weight of between 5% and 60%.

Classes IPC  ?

• B01D 53/04 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse avec adsorbants fixes
• A61M 16/22 - Dispositifs d'absorption de dioxyde de carbone
• A62B 19/00 - Cartouches à substances absorbantes pour appareils respiratoires
• B01D 53/62 - Oxydes de carbone
• B01J 20/04 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant des composés des métaux alcalins, des métaux alcalino-terreux ou du magnésium
• B01J 20/20 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant du carbone libreCompositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant du carbone obtenu par des procédés de carbonisation

Abrégé

A method for detecting cellular or molecular analytes is provided. The method uses two types of engineered phages: a “capture” phage (bait phage) and a “signal” phage (reporter phage). Through this method it is possible to selectively bind a target analyte and thus recognize said target analyte.

Classes IPC  ?

• G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
• G01N 21/64 - FluorescencePhosphorescence
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques

Abrégé

The shock-absorbing device (10), particularly intended to be installed in protective devices such as helmets of any type whatsoever, comprises a hermetically closed container (11) containing in turn a non-Newtonian shock-absorbing fluid (13). The invention also concerns a helmet (30) comprising an internal component (31) to be placed resting on the head of a user and an external component (32) located mobile around the internal component (31), and at least one shock-absorbing device inserted between the internal (31) and external (32) components.

Classes IPC  ?

• A42B 3/12 - Dispositifs de rembourrage
• F16F 9/32 - Ressorts, amortisseurs de vibrations, amortisseurs de chocs ou amortisseurs de mouvement de structure similaire, utilisant un fluide ou moyen équivalent comme agent d'amortissement Parties constitutives

Abrégé

Bacillus haynesiiBacillus haynesii called VWC18 deposited at the Microbial Strain Collection of Latvia (MSCL) on 28 February 2023 with accession number P1649) and its uses in agriculture as a plant biostimulant, in particular for horticultural and floricultural crops.

Classes IPC  ?

• A01N 63/22 - Bacillus
• A01P 21/00 - Régulateurs de croissance des végétaux

Produits et services

Telecommunication services; communication by online blogs; streaming of data; communication of data via electronic mail; providing of access to documents, online, via a global computer network; providing access to multimedia content online; providing access to databases; providing access to online chats via social networks; providing Internet chatrooms; providing of access to databases and information via global computer networks; providing of access to data or documents stored electronically in central files for remote viewing; providing videoconferencing facilities; radio telecommunications; interactive communication services; teleconferencing services; transmission of digital files; transmission of the contents; providing access to a global computer network for the transfer and dissemination of information. Education and educational services and education; educational instruction; providing courses of instruction at post-graduate level; industrial training; university services; consultancy and information services in relation to the following fields: vocational guidance [education or training advice]; organisation of courses using distance learning methods; cultural services; developing international student exchange programs; museum curator services; presenting museum exhibitions; electronic library services; lending library services; organizing cultural and arts events; arranging of musical events; organisation of events for cultural, entertainment and sporting purposes; organisation of conferences, exhibitions and competitions; organisation and holding of fairs for cultural and educational purposes; organisation of sports tournaments; sporting activities; sporting services; conducting of sports camps; production of radio and television programmes; provision of facilities for tuition; publishing, reporting, and writing of texts; publishing services; production of podcasts; language interpreter services; arranging of award ceremonies to recognise achievement. Research services; consultancy in the field of scientific research; scientific testing services; medical research; veterinary research; research laboratories; scientific research and development; scientific research and analysis; preparation of reports, in relation to the following fields: research services; industrial research; providing temporary use of on-line, non-downloadable software for use in publishing and printing; hosting multimedia educational content; computer software design; maintenance of databases; maintenance of software; maintenance of websites; hosting of blogs; managing the web sites of others; design services; industrial design; product design and development; industrial design; consultancy services in the field of technological development; technological consultancy services for digital transformation; electronic data storage; archaeological exploration and research; urban planning.

Abrégé

A method for the manufacture of a composite material for the recovery of nutrients and/or pollutants from wastewater, the method comprising, in succession, the following phases: supply of at least one carbonate material; supply of at least one carbonaceous material; mixing the carbonate material with the carbonaceous material to obtain a mixture; and heating the mixture to a temperature above 600° C. to obtain a composite material.

Classes IPC  ?

• B01J 20/20 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant du carbone libreCompositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant du carbone obtenu par des procédés de carbonisation
• B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
• B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
• C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
• C02F 1/66 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par neutralisationAjustage du pH
• C02F 101/10 - Composés inorganiques

Produits et services

Preserved, frozen, dried and cooked fruits; Jellies, jams, compotes; Yoghurt; Fruit pulp; Fruit salads; Fruit chips. Fresh fruits; Plants.

Abrégé

The present invention relates to compositions comprising a polymeric matrix or a gel containing functional enzymes capable of re-creating under culture conditions the cell microenvironment existing in vivo. The present invention also relates to devices for cell cultures comprising such compositions, in particular hydrogel and the use thereof to control the chemical microenvironment of a cell culture or mimic physiological or pathological conditions of the in vivo cells. The compositions and the devices described herein could be also used in vitro for evaluating the therapeutic effect of a compound on a determined cell line or on primary cells.

Classes IPC  ?

• C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
• C12N 5/09 - Cellules tumorales
• C12N 9/00 - Enzymes, p. ex. ligases (6.)ProenzymesCompositions les contenantProcédés pour préparer, activer, inhiber, séparer ou purifier des enzymes
• C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase
• C12N 9/04 - Oxydoréductases (1.), p. ex. luciférase agissant sur des groupes CHOH comme donneurs, p. ex. oxydase de glucose, déshydrogénase lactique (1.1)
• C12N 9/08 - Oxydoréductases (1.), p. ex. luciférase agissant sur le peroxyde d'hydrogène comme accepteur (1.11)
• C12N 11/04 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique piégées à l’intérieur du support, p. ex. dans un gel ou dans des fibres creuses
• C12N 11/06 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique attachées au support au moyen d'un agent de pontage
• C12N 11/087 - Polymères acryliques
• C12N 11/089 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique le support étant un polymère synthétique obtenu autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone
• C12N 11/12 - Cellulose ou ses dérivés
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

Sterilization method using plasma for sterilizing objects, wherein it is provided to introduce the objects to be sterilized into a sterilization chamber (13) and covey toward the latter a flow of air coming from a feed pipe (17) on which a plasma generator device (30) is disposed able to generate one or more gaseous compounds comprising a mixture of reactive oxygen species (ROS) and of reactive nitrogen species (RNS) so that the air is the carrier fluid which conveys the gaseous compounds toward the sterilization chamber (13); the method also provides to control the electric power used to produce the plasma as a function of the composition and/or the quantity of reactive species present in the sterilization chamber (13).

Classes IPC  ?

• A61L 2/14 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des phénomènes physiques du plasma, c.-à-d. des gaz ionisés
• A61L 101/02 - Matériaux inorganiques

Produits et services

Arranging and conducting of educational courses in the field of sports; Education services, namely, providing of classes, seminars, educational conventions, workshops, in the fields of foreign languages and literature, agriculture, architecture, arts and humanities, economics, education sciences, engineering, exercise and sport sciences, chemistry, law, mathematical, physical and natural sciences, medicine, pharmacy, political sciences, preservation of the cultural heritage, psychology, statistical sciences, veterinary medicine; Education services, namely, providing online instruction in the fields of education via an online website; Educational examination services; Educational services, namely, conducting distance learning instruction at the university level; Entertainment, namely, live music concerts; Lending library services; Live musical theater performances; Organization of sports competitions; Organizing community sporting and cultural events; Organizing events in the field of foreign languages and literature, agriculture, architecture, arts and humanities, economics, education sciences, engineering, exercise and sport sciences, chemistry, law, mathematical, physical and natural sciences, medicine, pharmacy, political sciences, preservation of the cultural heritage, psychology, statistical sciences, veterinary medicine for cultural or educational purposes; Organizing, arranging, and conducting football, basketball, soccer, rugby, volleyball, gymnastics, water sports, cricket, hockey, softball, ultimate flying disc, martial arts, dancing events, fitness, tennis, free climbing, athletics, row, rafting, cycling, horse riding, fencing events; Providing classroom instruction at the university level; Providing educational examination for certification in the field of university level education; Providing training in the field of foreign languages and literature, agriculture, architecture, arts and humanities, economics, education sciences, engineering, exercise and sport sciences, chemistry, law, mathematical, physical and natural sciences, medicine, pharmacy, political sciences, preservation of the cultural heritage, psychology, statistical sciences, veterinary medicine; Publication of books, of magazines, of journals, of newspapers, of periodicals, of catalogs, of brochures; Rental of sports equipment, except vehicles; Special event planning for social entertainment purposes; Sports training; Training services in the field of foreign languages and literature, agriculture, architecture, arts and humanities, economics, education sciences, engineering, exercise and sport sciences, chemistry, law, mathematical, physical and natural sciences, medicine, pharmacy, political sciences, preservation of the cultural heritage, psychology, statistical sciences, veterinary medicine; Vocational guidance Design and development of computer hardware and software; Scientific and technological services, namely, research and design in the field of information technology consultation; Scientific and technological services, namely, industrial analysis and research services in the field of science, engineering, business, health, social sciences, chemistry, chemical analysis, computer programming, engineering, materials testing, physics and surveying, environmental protection consultancy Horticulture services; Hygienic and beauty care for animals; Hygienic and beauty care for human beings; Medical services; Plant care services; Spreading of fertilizers and other agricultural chemicals; Tree care services; Veterinary services

Produits et services

Computer software for authorising access to databases; Computer software for creating searchable databases of information and data; Data mining software. Data processing; Computerized file management; Management and compilation of computerised databases; Collating of data in computer databases; Updating and maintenance of data in computer databases; Compilation of computer databases; Systemization of information into computer databases. Providing access to databases; Communications services for accessing a database. Conducting courses, seminars and workshops; Library services provided by means of a computerised database; Publication of material which can be accessed from databases or from the internet; Bibliographic information; Electronic publishing services. Technical advisory services relating to data processing; Data warehousing; Data mining; Maintenance of databases; Database design and development; Design and development of computer database software; Consultancy relating to the design and development of computer database programs; Installation, maintenance and updating of database software; Scientific research conducted using databases; Consultancy relating to computer database programs; Providing on-line non-downloadable software for database management; Development, updating and maintenance of software and database systems; Technological research relating to computers; Providing on-line information in the field of technological research from a computer database or the Internet; Providing scientific research information and results from an online searchable database.

Abrégé

The present invention pertains to a new nanostructured composite material with a layered hydrotalcite-type ternary structure of CuMgAI LDH (layered double hydroxides) and comprising particles of metal copper Cu° and particles containing cuprous ion Cu+(such as cuprous oxide), as a redox couple Cu°/Cu+, preferably placed in intimate contact with the layered hydrotalcite-type structure.

Classes IPC  ?

• C25B 3/26 - Réduction du dioxyde de carbone
• C25B 11/052 - Électrodes comportant un substrat et un ou plusieurs revêtements électro-catalytiques
• C25B 11/073 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique
• C25B 11/091 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques
• B01J 23/00 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
• C01F 7/00 - Composés de l'aluminium
• C25B 1/20 - Hydroxydes
• C25B 1/50 - Procédés

Abrégé

An abiotic biofuel cell comprising an anodic compartment comprising an anodic chamber, wherein said anodic chamber contains a first electrolytic solution, comprising an alkaline solution and a biofuel dispersed in said alkaline solution, and an anodic-chamber electrode in contact with the first electrolytic solution; a cathodic compartment comprising a cathodic chamber, wherein said cathodic chamber contains a second electrolytic solution, comprising an electron acceptor, and a cathodic-chamber electrode in contact with said second electrolytic solution; and ion-selective means adapted to separate the anodic chamber and the cathodic chamber and to be in fluid communication therewith; a plant comprising this abiotic biofuel cell and an operating process thereof.

Classes IPC  ?

• H01M 8/16 - Éléments à combustible biochimique, c.-à-d. éléments dans lesquels des micro-organismes agissent comme catalyseurs

Abrégé

Zea mays,ZeaZea having an improved root phenotype are provided.

Classes IPC  ?

• A01H 1/04 - Procédés de sélection
• C12Q 1/6895 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les plantes, les champignons ou les algues

Abrégé

The present invention relates to a Method to determine the depth of a scene (I) from at least one digital image (R, T) of said scene (I), comprising the following steps: A. acquiring said at least one digital image (R, T) of said scene (I); B. calculating a first disparity map (DM1) from said at least one digital image (R, T), wherein said first disparity map (DM1) consists of a matrix of pixels pij with i=1, . . . , M and j=1, . . . , N, where i and j indicate respectively the line and column index of said first disparity map (DM1), and M and N are positive integers; C. calculating a second disparity map (DM2), by a neural network, from said at least one digital image (R, T); D. selecting a plurality of sparse depth data Sij relative to the respective pixel pij of said first disparity map (DM1); E. extracting said plurality of sparse depth data S ii from said first disparity map (DM1); and F. optimizing said second disparity map (DM2) by said plurality of sparse depth data S ii, training at least one portion of said neural network with the information relative to said depth of said scene (I) associated with said sparse depth data Sij. The present invention relates to a Method to determine the depth of a scene (I) from at least one digital image (R, T) of said scene (I), comprising the following steps: A. acquiring said at least one digital image (R, T) of said scene (I); B. calculating a first disparity map (DM1) from said at least one digital image (R, T), wherein said first disparity map (DM1) consists of a matrix of pixels pij with i=1, . . . , M and j=1, . . . , N, where i and j indicate respectively the line and column index of said first disparity map (DM1), and M and N are positive integers; C. calculating a second disparity map (DM2), by a neural network, from said at least one digital image (R, T); D. selecting a plurality of sparse depth data Sij relative to the respective pixel pij of said first disparity map (DM1); E. extracting said plurality of sparse depth data S ii from said first disparity map (DM1); and F. optimizing said second disparity map (DM2) by said plurality of sparse depth data S ii, training at least one portion of said neural network with the information relative to said depth of said scene (I) associated with said sparse depth data Sij. The present invention also relates to a system (S) for determining the depth of a scene (I) starting from at least one digital image (R, T) of said scene (I).

Classes IPC  ?

• G06T 7/593 - Récupération de la profondeur ou de la forme à partir de plusieurs images à partir d’images stéréo

Abrégé

The present invention relates to chimeric polypeptides comprising a scaffold polypeptide and one or more exogenous polypeptides, wherein the scaffold polypeptide comprises a backbone protein 2a (BP-2a) Domain 3 (D3) polypeptide in which at least one endogenous loop has been partially or wholly replaced by an exogenous polypeptide. The present invention also relates to nanoparticles, outer membrane vesicles, pharmaceutical compositions, vaccines, arrays and kits comprising said chimeric polypeptides, methods of their production, and uses thereof in therapy and antibody screening.

Classes IPC  ?

• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
• C12N 15/62 - Séquences d'ADN codant pour des protéines de fusion

Abrégé

Phage for the specific capture of the SARS-CoV-2 virus, said phage being an M13 phage engineered to display on the P8 protein of its coat either FHKGGYEKTWKLGD sequence peptides or EFTSKAR sequence peptides, said peptides having speci fic af finity for the Spike S I protein of the SARS-CoV-2 virus.

Classes IPC  ?

• C07K 14/165 - Coronaviridae, p. ex. virus de la bronchite infectieuse aviaire
• G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus

Abrégé

Metal based nanoparticles coated with a polymer functionalized with thiol groups and 5 -NH groups, said polymer preferably being selected among thiolated chitosan, thiolated and aminated alginic acid, thiolated and aminated hyaluronic acid, or a protein preferably selected from the group consisting of albumin and gelatin, or a synthetic thiolated and aminated polymer, preferably α-thio-ω-amino polyethylene glycols; wherein said groups are linked to a ligand of the integrin family receptors, 10 preferably a peptide containing an integrin binding motif, and antibody or part of an antibody, a peptidomimetic or an aptamer, via a heterobifunctional crosslinker, the crosslinker bearing functional groups able to bind to amino groups, preferably selected from the group consisting of N-hydroxysuccinimidyl ester group (NHS ester), an isocyanate group (-NCO), an isothiocyanate group (-NCS), a Sulfo-N-15 hydroxysuccinimidyl ester group (sulfo-NHS ester), or a carboxylic acid group which is connected by activation with carbodiimide coupling agents; and/or a functional group able to bind thiol groups, preferably selected from the group consisting of: a maleimide group, a terminal vinyl group or a terminal alkyne group; and/or functional groups able to bind alkynes such as azides; and/or functional groups able 20 to bind azides, such as alkynes.

Classes IPC  ?

• A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
• A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
• A61K 49/22 - Préparations pour échographiePréparations pour imagerie par ultrasons

Abrégé

in vitroin vitro cell culturing and packaging for food and beverages, onto a target substrate, as well as to functional substrates obtainable from said methods and kits to be used in said methods.

Classes IPC  ?

• B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux
• B29C 64/112 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des gouttelettes individuelles, p. ex. de buses de jet
• B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 80/00 - Produits obtenus par fabrication additive
• B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
• B41M 3/00 - Procédés d'impression pour des travaux imprimés d'un genre particulier, p. ex. motifs
• G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes

Abrégé

A circuit includes a clock input node, a first signal input node configured to receive a first modulated signal switching between a first DC voltage and a second DC voltage, a bias circuit, a first output node, a first capacitor, a second capacitor, and switching circuitry coupled to the first capacitor and the second capacitor. Control circuitry is configured to initially set the switching circuitry in a first configuration in response to the first modulated signal having the second DC voltage, thereby charging the first capacitor to the second DC voltage and charging the second capacitor to the first DC voltage, and subsequently set the switching circuitry in a second configuration in response to an edge detected in the clock signal, thereby producing the first threshold voltage at the first output node after charge redistribution taking place between the first and second capacitors.

Classes IPC  ?

• H03K 5/00 - Transformation d'impulsions non couvertes par l'un des autres groupes principaux de la présente sous-classe
• H03K 3/0233 - Circuits bistables
• H03K 5/08 - Mise en forme d'impulsions par limitation, par application d'un seuil, par découpage, c.-à-d. par application combinée d'une limitation et d'un seuil
• H03L 7/099 - Détails de la boucle verrouillée en phase concernant principalement l'oscillateur commandé de la boucle
• H04L 25/06 - Moyens pour rétablir le niveau à courant continuCorrection de distorsion de polarisation
• H04L 27/06 - Circuits de démodulationCircuits récepteurs

Abrégé

The present invention relates to the stabilization of lipases in layered double-hydroxide structures, polymers containing such stabilized lipases and methods for manufacturing enzymatically degradable polymers.

Classes IPC  ?

• C12N 11/093 - Polyuréthanes
• C12N 11/096 - PolyestersPolyamides
• C12N 11/14 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support inorganique
• C12N 9/18 - Hydrolases agissant sur les esters d'acides carboxyliques
• C12N 9/20 - Scission des triglycérides, p. ex. au moyen de lipase
• C12N 9/96 - Stabilisation d'une enzyme par formation d'un adduct ou d'une compositionFormation de conjugaisons d'enzymes
• C08J 11/10 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation

Abrégé

The present invention stands directed at the use of nanoporous cerium oxide nanoparticle macro-structures as autoxidation inhibitors of organic compounds susceptible to autoxidation. The nanoporous cerium oxide nanoparticle macrostructures are more specifically employed in combination with a co-antioxidant.

Classes IPC  ?

• C09K 15/02 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés inorganiques
• C09K 15/04 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés organiques
• C08K 3/22 - OxydesHydroxydes de métaux
• C08K 5/01 - Hydrocarbures

Abrégé

Use of nanoporous cerium oxide nanoparticle macro-structures as autoxidation inhibitors of organic compounds susceptible to autoxidation. The nanoporous cerium oxide nanoparticle macrostructures are more specifically employed in combination with a co-antioxidant.

Classes IPC  ?

• C01F 17/235 - Oxydes ou hydroxydes de cérium
• B01F 23/50 - Mélange de liquides avec des solides
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites

Abrégé

The present invention relates to a detection system (1, T, 1") of radiation emitted by a source (C) comprising: at least one detection unit (2, 2', 2"), having a support substrate (21 ), a detection layer (22), arranged on said support substrate (21 ) and comprising one or more detection sensors (4), to detect the radiation emitted by a contaminating agent (C) by generating an electrical signal following the interaction with the ionizing radiation, and an insulating film (23), arranged on said detection layer (22), with which the contaminating agent (C) can come into contact, so that the ionizing radiation emitted by said agent is detected by one or more detection sensors (4); and at least one interaction terminal (3), connected to said detection unit (2, 2', 2") and configured to detect and communicate the position of said contaminant (C) based on the detection sensors affected by the ionizing radiation emitted by said contaminant (C). The present invention also relates to a detection unit (2, 2', 2") and a method for detecting radiations emitted by a source (C).

Classes IPC  ?

• G01T 1/02 - Dosimètres
• G01T 1/169 - Exploration, localisation de surfaces contaminées
• G01T 1/29 - Mesure effectuée sur des faisceaux de radiations, p. ex. sur la position ou la section du faisceauMesure de la distribution spatiale de radiations

Abrégé

An apparatus induces and autonomously maintains a state of hypometabolism for long time periods in people who would otherwise suffer from a significant deterioration of their vital functions and a shorter life expectancy, or people who will have to stay in a space environment for a long time. The apparatus, made up of a double enclosure, includes a chamber for housing one person, which is equipped with means for controlling the person's vital functions and the environmental conditions, with the possibility of autonomously modifying the environmental parameters and dosing the administration of substances according to data obtained from measured physiological variables. Outside the chamber there is an interspace containing a liquid for shielding any radiation. A non-invasive monitoring of the main vital functions includes oxygen consumption, carbon dioxide production, heart rate, hemoglobin saturation, temperature of various body districts, muscular tone, electroencephalographic activity, respiratory rate and exchanged respiratory volumes.

Classes IPC  ?

• A61H 33/00 - Bains pour usages thérapeutiques ou hygiéniques particuliers

Abrégé

The present invention relates to a synthetic peptide comprising the following elements from the N-terminus to the C-terminus: a) a first cell-penetrating peptide or functional fragments or derivatives, or biologically active variants thereof and b) a second peptide with agonist activity of OR1 and OR2 receptors or functional fragments or derivatives, or biologically active variants thereof.

Classes IPC  ?

• C07K 14/72 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire pour des hormones
• A61K 38/16 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• A61P 29/02 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS] sans effet anti-inflammatoire
• A61P 35/00 - Agents anticancéreux
• C07K 7/08 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 12 à 20 amino-acides

Abrégé

The present invention relates to a method for preparing an inactivated virus and an antiviral vaccine based on an inactivated virus, to be used both in the medical field and in the veterinary field, wherein the step of inactivating the virus is capable of safeguarding the antigenic protein structure of the virus itself, such as, for example, SARS-CoV-2.

Classes IPC  ?

• C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification

Produits et services

Downloadable and recorded content; Downloadable publications; Electronic publications, downloadable; Downloadable electronic publications in the nature of magazines; Software; Education software; Computer software for creating databases searchable by means of a search function; Databases; Computer software applications, downloadable; Downloadable applications for use with mobile devices; Teaching apparatus and instruments and Teaching apparatus and equipment; USB flash drives; USB chargers; USB cables; USB adapters; Battery chargers; Power banks; Decorative magnets; Covers for smartphones; Cases for tablet computers; Mouse pads; Electronic memories. Watches; Alarm clocks; Pins [jewellery]; Jewellery charms; Tie clips; Cuff links; Medals; Jewelry cases [caskets or boxes]; Key rings. Teaching materials [except apparatus]; Index files; Books; Printed matter; Planners [printed matter]; Printed calendars; Stationery; Illustrated wall maps; Bookplates; Photographs [printed]; Seals [stamps]; Stamps [seals]. Bags; Bags for sports; Purses; School bags; Rucksacks; Daypacks; Small purses; Pocket wallets; Card cases [notecases]; Business card cases; Key cases; Suitcases; Vanity cases, not fitted; Umbrellas. Drinking bottles; Bottles; Thermal insulated containers for food or beverage; Cups; Coffee mugs; Drinking glasses. Clothing; Tee-shirts; Sweat shirts; Socks; Scarves; Gloves [clothing]; Footwear; Headgear; Berets; Peaked caps. Games; Table-top games; Playing cards; Sports games; Educational games; Sporting equipment for physical exercise. Fresh fruits and vegetables; Raw agricultural products; Plants; Sowing seeds. Business assistance, management and administrative services; Business consulting; Human resources management and recruitment services; Compilation of statistics; Business analysis, research and information services; Advertising, marketing and promotional consultancy, advisory and assistance services; Management assistance for promoting business; Advice in the field of business management and marketing; Arranging of commercial and business contacts; Business networking services; Public relations services; Retail services in relation to the following goods: Software, USB memory devices, USB chargers, USB cables, USB adaptors, Battery charge devices, Power banks, decorative magnets, Smartphone cases, tablet cases, Mouse pads, Electronic storage and, Clocks, alarm clocks, Broches, trinkets, pendants, Tie clips, Cuff-links, Medals, Jewellery cases, Key rings, Instructional or teaching material (except apparatus); Retail services in relation to the following goods: Books, Printed matter, Planners (printed matter), Printed calendars, Stationery, Illustrated wall maps, bookplates, Photographs [printed], seals, Stamps [seals], Bags, Bags for sports, Purses, School bags, Back packs, Haversacks, Small purses, pocket wallets, card cases (notecases), Business card cases, key cases [leatherware], Articles of luggage, Vanity cases not fitted for toiletry articles, Umbrellas, drinking flasks; Retail services in relation to the following goods: Bottles, thermal insulated containers for food or beverages, Cups, Coffee mugs, glasses, Clothing, T-shirts, sweatshirts, Socks, Sashes for wear, Gloves, footwear, headgear, Berets, Visor caps, Games, board games, playing cards, Games of sport, Educational games, Sporting equipment for physical exercise. Telecommunication services; Communication by online blogs; Streaming of data; Communication of data via electronic mail; Providing of documents, online, via a global computer network; Providing access to multimedia content online; Providing access to databases; Providing online chats via social networks; Providing internet chatrooms; Providing of access to databases and information via global computer networks; Providing of access to data or documents stored electronically in central files for remote viewing; Providing videoconferencing facilities; Radio telecommunications; Interactive communication services; Teleconferencing services; Transmission of digital files; transmission of the contents; Providing access to a global computer network for the transfer and dissemination of information. Education and educational services and Education; Educational instruction; Providing courses of instruction at post-graduate level; Industrial training; University services; Consultancy and information services in relation to the following fields: Vocational guidance [education or training advice]; Organisation of courses using distance learning methods; Cultural services; Developing international student exchange programs; Running of museums; Presenting museum exhibitions; Electronic library services; Lending library services; Organizing cultural and arts events; Arranging of musical events; Organisation of events for cultural, entertainment and sporting purposes; Organisation of conferences, exhibitions and competitions; Arranging and conducting of trade fairs For cultural and teaching purposes; Organisation of sports tournaments; Sporting activities; Sporting services; Conducting of sports camps; Production of radio and television programmes; Provision of facilities for tuition; Publishing, reporting, and writing of texts; Publishing services; Production of podcasts; Language interpreter services; Arranging of award ceremonies to recognise achievement. Research services; Consultancy in the field of scientific research; Scientific testing services; Medical research; Veterinary research; Research laboratories; Scientific research and development; Scientific research and analysis; Preparation of reports, in relation to the following fields: Research services; Industrial research; Providing temporary use of on-line, non-downloadable software for use in publishing and printing; Hosting multimedia educational content; Computer software design; Maintenance of databases; Maintenance of software; Maintenance of websites; Hosting of blogs; Managing the web sites of others; Design services; Industrial design; Product design and development; Industrial design; Consultancy services in the field of technological development; Technological consultancy services for digital transformation; Electronic data storage; Archaeological exploration and research; Urban planning. Medical treatment services provided by clinics and hospitals; Medical assistance; Medical clinic services; Medical counseling; Medical care; Medical screening; Providing medical information in the healthcare sector; Medical treatment services; Provision of medical services; Medical information; Arranging of medical treatment; Issuing of medical reports; Medical screening; Medical analysis services; Medical and healthcare clinics; Health care consultancy services [medical]; Advisory services relating to medical instruments; Medical examinations; Human healthcare services; Medical tele-reporting [medical services]; Animal healthcare services; Dentistry; Dental clinic services; Farming (animals); Agriculture, horticulture and forestry services; Farming services. Intellectual property services; Licensing of intellectual property; Consultancy relating to computer software licensing; On-line social networking services; Legal aid services; Legal advice.

Abrégé

The present invention relates to 4-chromone derivative compounds of general formula (I) and the medical use thereof as anticancer agents.

Classes IPC  ?

• A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61P 35/00 - Agents anticancéreux
• A61P 35/02 - Agents anticancéreux spécifiques pour le traitement de la leucémie

Abrégé

A device for interfacing at least one filamentous structure, with real or simulated biological tissue and a system for regeneration, repair, replacement, or simulation of tendon and/or ligamentous tissue. The device comprises one or more bodies for anchoring a filamentous structure. The one or more bodies may include at least one capstan for wrapping the filamentous structure, and at least one porous portion having a trabecular structure. The system comprises the device and at least one filamentous structure having a plurality of nanofiber assemblies that are obtained by electrospinning. The plurality of assemblies may be arranged to form a single bundle, with the bundle being wrapped to the capstan.

Classes IPC  ?

• A61F 2/08 - MusclesTendonsLigaments

Abrégé

An in-memory computation (IMC) circuit includes a memory array formed by memory cells arranged in row-by-column matrix. Computational weights for an IMC operation are stored in the memory cells. Each column includes a bit line connected to the memory cells. A biasing circuit is connected between each bit line and a corresponding column output. A column combining circuit combines and integrates analog signals at the column outputs of the biasing circuits. Each biasing circuit operates to apply a fixed reference voltage level to its bit line. Each biasing circuit further includes a switching circuit that is controlled to turn on for a time duration controlled by asps comparison of a coefficient data signal to a ramp signal to generate the analog signal dependent on the computational weight. The ramp signal is generated using a reference current derived from a reference memory cell.

Classes IPC  ?

• G11C 16/06 - Circuits auxiliaires, p. ex. pour l'écriture dans la mémoire
• G11C 13/00 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage non couverts par les groupes , ou

Abrégé

It is described a silica nanoparticle comprising: a) a silicate network core with a diameter in a range from 10 nm to 500 nm, preferably from 20 nm to 250 nm, wherein at least a luminophore (dye) is confined in the said silicate network core, or covalently linked to the silicate network of the core because said luminophore (dye) has an anchoring moiety able to form at least a covalent link with the silicate network core, b) a shell layer over the silicate network core a) incorporating dye/s, said shell layer b) with a thickness from 0.5 to 7 nm, preferably from 0.5 to 6 nm, more preferably from 1 to 5 nm, comprising colloidal stabilizer agent/s, selected from the group comprising: sterical or electrostatic antifouling agents or polyether antifouling agents.

Classes IPC  ?

• C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p. ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires
• B82Y 40/00 - Fabrication ou traitement des nanostructures
• B82Y 5/00 - Nanobiotechnologie ou nanomédecine, p. ex. génie protéique ou administration de médicaments

Abrégé

The present invention relates to a process for the preparation of a porous hierarchical scaffold characterized by internal pores organized according to a hierarchical structure, for the regeneration, replacement and/or simulation of a bone tissue, in particular of the trabecular and/or cortical bone tissue. The present invention further relates to the porous hierarchical scaffold obtainable by such process and to the uses thereof. The invention further relates to the use of a sacrificial hierarchical scaffold for the preparation of such porous hierarchical scaffold.

Classes IPC  ?

• A61F 2/28 - Os
• A61L 27/34 - Matériaux macromoléculaires
• A61L 27/56 - Matériaux poreux ou cellulaires

Abrégé

The present invention relates to a process for detecting an analyte in an isolated sample, wherein said analyte is a target nucleic acid, comprising the steps of: supplying a sample comprising at least one nucleic acid; heat-treating said sample; contacting the heat-treated sample with at least two single-stranded nucleic acid probes in which each of said at least two single-stranded nucleic acid probes is complementary to a corresponding portion of said target nucleic acid; adding an active luminophore; determining a luminescence signal generated by the active luminophore.

Classes IPC  ?

• C12Q 1/6825 - Détecteurs faisant intervenir la détection d’acides nucléiques

Abrégé

In accordance with an embodiment, an envelope detector includes a first transistor having a first current conduction terminal coupled to a first connection node; a second current conduction terminal coupled to an intermediate node; and a control terminal coupled the signal input node and to a biasing node; a second transistor having a first current conduction terminal coupled to the intermediate node; a second current conduction terminal coupled to a second connection node; and a control terminal coupled to the biasing node; and a first temperature compensating transistor that is diode-connected and coupled between a compensation output node and the biasing node. The second connection node is coupled to the compensation output node and the first connection node is coupled to a detector output.

Classes IPC  ?

• H03F 1/02 - Modifications des amplificateurs pour augmenter leur rendement, p. ex. étages classe A à pente glissante, utilisation d'une oscillation auxiliaire
• H03F 1/32 - Modifications des amplificateurs pour réduire la distorsion non linéaire

Abrégé

A laparoscopic surgical instrument including a connection assembly, an end effector, and a manipulation unit. The instrument also includes a means for transmitting motion from the manipulation unit to the end effector. The means for transmitting motion may include a means for transmitting first rotational movement of the manipulation unit to the end effector in a way such that the end effector rotates around an axis that is orthogonal to the axis of the connection assembly. The means for transmitting motion may also include a means for transmitting a second rotational movement to the end effector in a way such that the end effector rotates around it's own axis that is parallel to the axis of the manipulation unit.

Classes IPC  ?

• A61B 17/32 - Instruments chirurgicaux coupants
• A61B 17/3201 - Ciseaux

Abrégé

An apparatus for sampling and detecting a pathogen in air comprising a first air sampling module, a second module for the isolation of viral RNA and a third module for amplification and detection of the viral RNA; thanks to the integration between the modules the apparatus is compact and portable and can be used for in situ sampling of air in closed environments such as ambulances or hospital rooms, air in the external environment and air exhaled by patients.

Classes IPC  ?

• C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
• G01N 1/22 - Dispositifs pour prélever des échantillons à l'état gazeux
• G01N 1/24 - Dispositifs d'aspiration
• C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]

Abrégé

A process for the activation of a vanadium/phosphorus mixed oxide catalyst ("VPO" catalyst) precursor, whereby the precursor is transformed into the corresponding active catalyst suitable for use in the production of maleic anhydride by partial oxidation of n-butane.

Classes IPC  ?

• B01J 27/198 - Vanadium
• B01J 37/10 - Traitement thermique en présence d'eau, p. ex. de vapeur d'eau
• C07C 51/215 - Préparation d'acides carboxyliques, de leurs sels, halogénures ou anhydrides par oxydation avec l'oxygène moléculaire de groupes hydrocarbyle saturés

Abrégé

A system and method for assessing biomechanical risk in the context of handling heavy loads in workplaces. The system and method are applicable during a normal working activity for acquisitions lasting a work shift. The acquired data are then analysed in relation to regulatory references and international standards for the assessment of the biomechanical risk from manual handling of loads.

Classes IPC  ?

• A61B 5/103 - Dispositifs de mesure pour le contrôle de la forme, du dessin, de la dimension ou du mouvement du corps ou de parties de celui-ci, à des fins de diagnostic
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

The invention relates to a faecal microbiota preparation from a monogastric herbivorous mammal for use in a method of therapeutically treating a dysbiosis disease in a dysbiotic omnivorous mammal.

Classes IPC  ?

• A23K 50/40 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux carnivores, p. ex. pour les chats ou les chiens
• A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques
• A61K 35/741 - Probiotiques

Abrégé

The present invention relates to a process for the production of mixtures comprising compounds having a number of carbon atoms ≥6, usable as jet fuel or as jet fuel precursors starting from one or more alcohols having from 2 (C2) to 4 (C4) carbon atoms, wherein said one or more alcohols are introduced into a continuously operating fixed bed catalytic reactor, in an amount from 1 to 100 mol%, in the vapour phase and at a temperature ranging from 200 to 450°C, said catalyst comprising metallic copper on a zirconia-based support, said metallic copper being in a percentage by weight ranging from 0.5% to 25% of the total weight of the catalyst. The present invention also relates to a plant for the production of a mixture comprising compounds having a number of carbon atoms >6, usable as a jet fuel or jet fuel precursor, starting from one or more alcohols having from 2 to 4 carbon atoms according to the process of the present invention, said plant comprising a continuously operating fixed bed catalytic reactor; a vaporiser placed upstream of said reactor and adapted to bring said one or more alcohols into the vapour phase; an inlet of said one or more alcohols in vapour phase and of inert gas toward the inside of said reactor, said inlet being connected to said vaporiser and to an inert gas source; an outlet of said mixture preferably connected to a condenser for the recovery of the products of interest and subsequent separations.

Classes IPC  ?

• B01J 21/06 - Silicium, titane, zirconium ou hafniumLeurs oxydes ou hydroxydes
• C10G 3/00 - Production de mélanges liquides d'hydrocarbures à partir de matières organiques contenant de l'oxygène, p. ex. huiles, acides gras

Abrégé

Device (10) for converting wave energy into electrical energy comprising a floating structure ( 11 ), a rotating member ( 12) configured to be rotated with respect to the floating structure (11) and pivoted to a converter member (13) attached to said floating structure (11) and configured to convert the movement of said rotating member (12) into electrical energy.

Classes IPC  ?

• F03B 13/20 - Utilisation du mouvement relatif entre un élément déplacé par les vagues et un autre élément les deux éléments étant mobiles par rapport au fond ou au bord de la mer
• F03B 13/18 - Utilisation du mouvement relatif entre un élément déplacé par les vagues et un autre élément l'autre élément étant fixé, à au moins un point, par rapport au fond ou au bord de la mer

Abrégé

A circuit includes a memory array with memory cells arranged in a matrix of rows and columns, where each row includes a word line connected to the memory cells of the row, and each column includes a bit line connected to the memory cells of the column. Computational weights for an in-memory compute operation (IMCO) are stored in the memory cells. A word line control circuit simultaneously actuates word lines in response to input signals providing coefficient data for the IMCO by applying word line signal pulses. A column processing circuit connected to the bit lines processes analog signals developed on the bit lines in response to the simultaneous actuation of the word lines to generate multiply and accumulate output signals for the IMCO. Pulse widths of the signal pulses are modulated to compensate for cell drift. The IMCO further handles positive/negative calculation for the coefficient data and computational weights.

Classes IPC  ?

• G11C 11/4096 - Circuits de commande ou de gestion d'entrée/sortie [E/S, I/O] de données, p. ex. circuits pour la lecture ou l'écriture, circuits d'attaque d'entrée/sortie ou commutateurs de lignes de bits
• G06F 7/544 - Méthodes ou dispositions pour effectuer des calculs en utilisant exclusivement une représentation numérique codée, p. ex. en utilisant une représentation binaire, ternaire, décimale utilisant des dispositifs n'établissant pas de contact, p. ex. tube, dispositif à l'état solideMéthodes ou dispositions pour effectuer des calculs en utilisant exclusivement une représentation numérique codée, p. ex. en utilisant une représentation binaire, ternaire, décimale utilisant des dispositifs non spécifiés pour l'évaluation de fonctions par calcul
• G11C 11/4074 - Circuits d'alimentation ou de génération de tension, p. ex. générateurs de tension de polarisation, générateurs de tension de substrat, alimentation de secours, circuits de commande d'alimentation
• G11C 11/4076 - Circuits de synchronisation
• G11C 11/408 - Circuits d'adressage
• G11C 11/4094 - Circuits de commande ou de gestion de lignes de bits

Abrégé

A prosthetic implant (100) of the ESR (energy-storing-and-returning) type, comprises an upper assembly (200) and a lower assembly (300), configured to define a foot and including a lower blade (400b), an intermediate blade (400b) and an upper blade (400c). The upper blade (400c), the lower blade (400a) and the intermediate blade (300c) are fastened stably to each other at at least one connecting point (C) located in the front region (300a) or in the middle region (300b) of the foot. An articulated joint (5009) is interposed between the lower assembly (300) and the upper one (200) to allow relative motion between them. The implant comprises a connector (600) having a first end (600a) that is connected to the upper assembly (200) and a second end (600b) that is connected to the intermediate blade (400b) of the lower assembly (300). At least one between the first and the second end (600a, 600b) of the connector (600) is movable along a movement direction (X) to vary the force applied on the intermediate blade (400b) of the lower assembly (300).

Classes IPC  ?

• A61F 2/66 - PiedsArticulations de la cheville

Abrégé

A device (1) for connecting construction elements, comprising a first member (2), intended to be connected to a first construction element, and a second member (3), intended to be connected to a second construction element, so that, in use, the device (1) is interposed between said first and second construction elements so as to create a permanent connection between them; the first member (2) is configured so as to define a seat inside which the second member (3) is at least partially inserted. The device (1) also comprises at least one dissipation unit (4), interposed between said first member (2) and said second member (3), configured to absorb the energy which, due to external stress, is transmitted by said first construction element to said second construction element. The dissipation unit (4) comprises a plurality of dissipative elements (5), substantially arch-shaped, fixed to the first member and the second member.

Classes IPC  ?

• E04H 9/02 - Bâtiments, groupes de bâtiments ou abris conçus pour résister à des situations extérieures anormales, p. ex. à des bombardements, à des séismes ou à des climats extrêmes, ou pour se protéger de ces situations résistant aux séismes ou à l'effondrement du sol

Abrégé

The present invention relates to various aspects of the three-dimensional printing processes, and in particular a photo-crosslinkable composition and its components from renewable sources and having similar, if not better, performances in particular as regards both the tensile strength and the flexibility / deformability, compared to the currently available formulations of origin fossil, so as to provide a more acceptable alternative from the point of view of environmental impact compared to similar components of fossil origin.

Classes IPC  ?

• B29C 64/10 - Procédés de fabrication additive
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 80/00 - Produits obtenus par fabrication additive
• C08F 283/01 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères prévus par la sous-classe sur des polyesters non saturés
• C08F 290/06 - Polymères prévus par la sous-classe
• C08L 51/08 - Compositions contenant des polymères greffés dans lesquels le composant greffé est obtenu par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carboneCompositions contenant des dérivés de tels polymères greffés sur des composés macromoléculaires obtenus autrement que par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone

Abrégé

2+.

Classes IPC  ?

• G01N 15/06 - Recherche de la concentration des suspensions de particules
• G01N 31/22 - Utilisation des réactifs chimiques
• G01N 33/20 - Métaux
• G01N 15/075 - Recherche de la concentration des suspensions de particules par des moyens optiques

Abrégé

Limosilactobacillus vaginalisLimosilactobacillus vaginalisLimosilactobacillus vaginalis BC17 strain deposited with number DSM 34059. The strain can be incorporated into a liquid or solid composition that can be administered orally or buccally and the human subject can be a neonate or a suckling. The strain can also be used to prepare compositions that are applicable to the skin of the nipples of a breast-feeding woman.

Classes IPC  ?

• A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques
• A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
• A61K 35/00 - Préparations médicinales contenant des substances ou leurs produits de réaction de constitution non déterminée

Abrégé

A farming system (1) for row crop installations (10) comprises: a first plurality of plants (10A) and a second plurality of fruit or vegetable plants (10B), disposed along a first longitudinal axis (L1) and a second longitudinal axis (L2), respectively, and mutually spaced along a transverse direction (T) to form a first row (F1) and a second row (F2); a supporting structure (11), configured to support the plants and including, for the first row (F1) and the second row (F2), a first plurality of posts (11A) and a second plurality of posts (11B); a first rail (12A), connected to the first plurality of posts (11A); a second rail (12B), connected to the second plurality of posts (11B). The first rail (12A) and the second rail (12B) are oriented longitudinally and spaced transversely from each other to define a track (12). The system comprises a trolley (13), movable along the track (12) and including a movement actuator (131), configured to move the trolley (13) on the track (12).

Classes IPC  ?

• B61L 27/04 - Systèmes automatiques, p. ex. commandés par les trainsPassage à la commande manuelle
• B61B 5/02 - Systèmes ferroviaires surélevés sans véhicules suspendus avec plusieurs rails
• B61C 3/02 - Locomotives ou automotrices électriques avec accumulateurs d'électricité
• B61C 13/00 - Locomotives ou automotrices caractérisées par leur utilisation dans des systèmes ou pour des buts particuliers
• B61D 15/00 - Autres véhicules ferroviaires, p. ex. véhicules à échafaudageAdaptation des véhicules pour leur utilisation sur voies ferrées
• B61L 27/30 - Systèmes de commande multiples côté voie, p. ex. commutation d'un système à un autre
• B61L 27/70 - Détails des communications côté voie
• B61L 25/02 - Indication ou enregistrement de la position ou de l'identité de véhicules ou de trains
• B61L 23/04 - Dispositifs de commande, d'avertissement ou autres dispositifs de sécurité le long de la voie ou entre les véhicules ou les trains pour contrôler l'état mécanique de la voie
• B60L 53/30 - Détails de construction des stations de charge

Abrégé

The present invention relates to a method for detecting cellular or molecular analytes, which method uses two types of engineered phages: a "capture" phage (bait phage) and a "signal"phage (reporter phage). Through this method it is possible to selectively bind a target analyte and thus recognize said target analyte.

Classes IPC  ?

• G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus

Abrégé

Device (1) for the placement of organic tissue (2), in particular endocrine tissue, comprising : a hollow tubular base element (3) configured to house in a seat (5) at least one portion of the organic tissue (2); a pushing element (14) which can be inserted or is inserted on the inside of the base element (3) and can be or is coupled to it in a sliding manner; wherein the base element (3) is configured to at least partially penetrate a target tissue (8); the base element (3) further comprising a first opening (15), which is arranged in a distal zone (DZ) towards a first end (6) and is configured to let out and, hence, position the organic tissue (2) in the target tissue (8) through the action of the pushing element (14).

Classes IPC  ?

• A61B 17/425 - Instruments ou procédés de gynécologie ou d'obstétrique pour la reproduction ou la fertilisation

Abrégé

It is disclosed a method for evaluating the capacity of a serum to neutralise a virus. The method comprises the steps of: preparing a solution comprising at least one cell, at least one serum and at least one virus; placing the solution in contact with an organic electrochemical transistor comprising a source electrode, a drain electrode and a gate electrode, wherein the source and drain electrodes are electrically connected by means of a conductive channel comprising a conducting or semiconducting polymer; applying a potential difference between the drain electrode and the source electrode, applying a plurality of pulses of a potential difference between the gate electrode and the source electrode and measuring a respective plurality of values of pulses of current flowing through the channel; calculating a value of an estimation of a response time of the organic electrochemical transistor, as a function of the plurality of values of the measured current; comparing the value of the estimated response time with respect to a threshold value and detecting, as a function of said comparison, whether the serum has a neutralising capacity against the at least one virus.

Classes IPC  ?

• G01N 27/414 - Transistors à effet de champ sensibles aux ions ou chimiques, c.-à-d. ISFETS ou CHEMFETS
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus

Abrégé

A method for estimating a quantity profile of a volume (V) of soil, comprising the steps of : - placing in the soil volume a bi-dimensional or three- dimensional grid of quantity sensors, wherein each sensor of the grid is identified by a position represented by three-dimensional coordinates with respect to the center of the soil volume; - acquiring, in the same instant of time, a quantity value from each quantity sensor of the sensor grid, so as to obtain a bi-dimensional or three-dimensional grid of real quantity values; - applying a profiling function to the quantity value grid in order to obtain a fine grained quantity profile defined by a bi-dimensional or three dimensional extended grid of quantity values, each value of the extended grid being associated with a position represented by three dimensional coordinates with respect to the center of the soil volume, wherein the number of elements of the extended grid of quantity values is much greater than the number of quantity sensors.

Classes IPC  ?

• G01N 33/24 - Matériaux de la terre
• A01G 25/16 - Commande de l'arrosage
• G06Q 50/02 - AgriculturePêcheForesterieExploitation minière

Abrégé

A System for lifting a processing device (9) for a precision agricultural vehicle (1) comprising a base body (2) and a processing device (9) for carrying out an agricultural operation; the system comprises at least one lifting element (33), which can be coupled to the front portion (6) of the base body (2) by means of a kinematic mechanism (34); an interface element (35), which is arranged in the area of said at least one lifting element (33) and can mechanically be coupled to the processing device (9); an actuator device (36) configured to adjust at least the height position of said at least one lifting element (33); the kinematic mechanism (34) is configured to have said at least one lifting element (33) assume at least a first configuration and a second configuration; the lifting system (32) is configured to lift the processing device (9) by shifting from the first configuration to the second configuration.

Classes IPC  ?

• A01M 7/00 - Adaptations ou aménagements particuliers des appareils de pulvérisation de liquides aux fins couvertes dans la présente sous-classe
• A01B 63/00 - Dispositifs ou agencements de levage ou de réglage pour machines ou instruments agricoles

Abrégé

Use of a non-woven fabric comprising polylactic acid fibers for inoculation of to be mycorrhized plants.

Classes IPC  ?

• A01G 7/00 - Botanique en général
• A01G 29/00 - Dispositifs pour l'alimentation des racinesInjection d'engrais dans les racines
• C12N 1/14 - ChampignonsLeurs milieux de culture

Abrégé

The present invention relates to compounds of Formula (Ia) or pharmaceutically acceptable salts, hydrates, solvates, clathrates, polymorphs, stereoisomers thereof. It further discloses a pharmaceutical composition comprising compounds of Formula (Ia) and the use of compounds of Formula (Ib), in particular for the use in the treatment of diseases or disorders wherein disrupting Rad51-BRCA2 interaction is beneficial.

Classes IPC  ?

• C07D 401/04 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
• C07D 401/14 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant au moins trois hétérocycles

Abrégé

A NAB815 compound having the following formula (I), wherein: L is OA, R1 is -Dab, R2 is -Thr, R3 is -DThr, R4 is -Dab, R5 is -Dab, R6 is -DPhe, R7 is -Leu, R8 is -Abu, R9 is -Dab, R10 is -Thr, or a pharmaceutically acceptable salt thereof is provided for a use in the treatment and/or the prevention of the hemolytic-uremic syndrome.

Classes IPC  ?

• A61K 38/12 - Peptides cycliques
• A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins

Abrégé

The shock-absorbing device (10), particularly intended to be installed in protective devices such as helmets of any type whatsoever, comprises a hermetically closed container (11) containing in turn a non-Newtonian shock-absorbing fluid (13). The invention also concerns a helmet (30) comprising an internal component (31) to be placed resting on the head of a user and an external component (32) located mobile around the internal component (31), and at least one shock-absorbing device inserted between the internal (31) and external (32) components.

Classes IPC  ?

• A42B 3/12 - Dispositifs de rembourrage
• A42B 3/06 - Calottes amortissant les chocs, p. ex. des casques anticollision

Abrégé

It is described a method for cleaning surfaces of an item of historical-artistic interest comprising a step of applying a wipe (1), comprising a membrane of non-woven fabric (2) soaked with a solvent, to a surface layer to be removed of said item of historical-artistic interest; it is also described a wipe (1) for cleaning surfaces of an item of historical- artistic interest, in particular a painting work, adapted to carry out said method, and a kit (10) comprising a plurality of wipes (1).

Classes IPC  ?

• B44D 7/00 - Préservation des peintures, p. ex. par vernissage
• B05D 1/28 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces par transfert de liquides ou d'autres matériaux fluides, à partir de la surface d'éléments porteurs, p. ex. de pinceaux, tampons, rouleaux
• B08B 1/00 - Nettoyage par des procédés impliquant l'utilisation d'outils
• B08B 3/08 - Nettoyage impliquant le contact avec un liquide le liquide ayant un effet chimique ou dissolvant
• B08B 11/00 - Nettoyage d'objets flexibles ou fragiles par des procédés ou avec un appareillage spécialement adaptés à cet effet