The present invention addresses the problem of providing a novel heat stress relieving agent that can be taken easily, conveniently and safely even by infants and the elderly, who are susceptible to heat stress such as heat illness, that rapidly promotes sweating in a heat stress environment, and that prevents, alleviates, or improves symptoms and disorders caused by heat stress, such as heat illness. The above problem is solved by providing a heat stress relieving agent containing glycosyl hesperetin as an effective ingredient, and a basal body temperature maintaining agent containing glycosyl hesperetin as an effective ingredient.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 29/02 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS] sans effet anti-inflammatoire
2.
SOLID FOOD, PRODUCTION METHOD THEREOF, AND METHOD FOR IMPARTING TEXTURE TO SOLID FOOD
An object of the present invention is to provide a protein-containing solid food that has both the excellent texture and dietary fiber properties, and the above object is attained by providing a solid food comprising a cyclic tetrasaccharide whose structure is represented by cyclo {→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1-3)-α-D-glucopyranosyl-(1→} and/or a glycosyl derivative thereof, and a protein.
A23L 15/00 - Produits à base d’œufsLeur préparation ou leur traitement
A23J 3/22 - Traitement des protéines pour l'alimentation par texturation
A23L 11/00 - Légumes secs, c.-à-d. fruits de plantes légumineuses, pour l'obtention d'alimentsProduits dérivés de légumineusesLeur préparation ou leur traitement
The present invention addresses the problem of providing means for enhancing the spiciness of a spice. The problem is solved by providing an agent for enhancing spiciness, the agent containing glucosyl naringenin.
A23L 27/00 - ÉpicesAgents aromatiques ou condimentsÉdulcorants artificielsSels de tableSubstituts diététiques du selLeur préparation ou leur traitement
A novel hair-setting composition having sufficient hair-setting ability, and a means to obtain such a hair-setting composition. An agent is provided for enhancing a hair-setting ability comprising an isomaltooligosaccharide as an active ingredient, and a hair-setting composition comprising the agent.
An object of the present invention is to provide a composition having an effective GLP-1 secretion-promoting effect. The present invention attains this object by providing a composition for promoting GLP-1 secretion, comprising component (A) and component (B) as active ingredients, wherein said component (A) is a glycosyl naringenin and said component (B) is one or more selected from a group consisting of α-pinene, β-pinene, sabinene, camphene, valencene, β-caryophyllene, β-ionone, methyl anthranilate, methyl N-methylanthranilate, thymol, and nootkatone.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
The purpose of the present invention is to provide a novel means for improving the mouthfeel of a protein-containing ingredient and to provide a food/beverage product composition containing a protein-containing ingredient that has an excellent mouthfeel. Using glucosyl naringin makes it possible to improve the mouthfeel of a protein-containing ingredient.
A23L 27/20 - Épices, agents aromatiques ou condiments synthétiques
A21D 13/064 - Produits à valeur nutritive modifiée, p. ex. à teneur en amidon modifiée à teneur en protéines modifiée
A23C 11/02 - Succédanés du lait, p. ex. compositions pour remplacer le lait dans le café au lait contenant au moins un composé d'origine non laitière comme source de matières grasses ou de protéines
A23G 1/44 - Produits à base de cacao, p. ex. chocolatLeurs succédanés caractérisés par la composition contenant des peptides ou des protéines
A23G 9/38 - Desserts glacés, p. ex. confiseries glacées, glacesMélanges correspondants caractérisés par la composition contenant des peptides ou des protéines
A23L 5/00 - Préparation ou traitement des aliments ou produits alimentaires en généralAliments ou produits alimentaires ainsi obtenusLeurs matériaux
A23L 11/00 - Légumes secs, c.-à-d. fruits de plantes légumineuses, pour l'obtention d'alimentsProduits dérivés de légumineusesLeur préparation ou leur traitement
The present invention provides an absorbent article that contains a water absorbent resin having excellent water absorption performance. The present invention relates to an absorbent article that contains a water absorbent resin comprising a water-soluble polymer in which an acidic group is introduced into starch or a partial degradation product thereof.
A61F 13/53 - Garnitures absorbantes, p. ex. serviettes ou tampons hygiéniques pour application externe ou interne au corpsMoyens pour les maintenir en place ou les fixerApplicateurs de tampons caractérisées par le milieu absorbant
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
A23L 5/00 - Préparation ou traitement des aliments ou produits alimentaires en généralAliments ou produits alimentaires ainsi obtenusLeurs matériaux
A61L 15/22 - Bandages, pansements ou garnitures absorbant les fluides physiologiques tels que l'urine, le sang, p. ex. serviettes hygiéniques, tampons contenant des matériaux macromoléculaires
8.
METHOD FOR IMPROVING PRODUCTIVITY IN LIVESTOCK AND/OR POULTRY AND METHOD FOR IMPROVING INTESTINAL FLORA IN LIVESTOCK AND/OR POULTRY
The present invention aims to provide means capable of improving the intestinal flora and the productivity of livestock and/or poultry, especially means for improving the weight gain, the feed conversion ratio, and the uniformity of livestock and/or poultry. The object is achieved by providing a method of improving the productivity of livestock and/or poultry, and a method of improving the intestinal flora of livestock and/or poultry, by feeding the livestock and/or poultry with a feed containing trehalose and probiotics, and providing a feed for livestock and/or poultry containing trehalose and probiotics.
A23K 10/18 - Ajout de micro-organismes ou de leurs produits d’extraction, p. ex. de protéines provenant d’organismes unicellulaires, à des compositions de produits alimentaires de micro-organismes vivants
A23K 50/10 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les ruminants
A23K 50/30 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les porcs
A23K 50/75 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les oiseaux pour la volaille
The purpose of the present invention is to provide a method for producing a water absorbent resin that has high production efficiency and excellent water absorbing capability. The present invention pertains to a method for producing a water absorbent resin that forms a physical gel through water absorption, the method comprising: a step (a1) for obtaining a partial degradation product of starch by lowering the molecular weight of starch; a step (a2) for obtaining a water-soluble polymer by introducing an acidic group to the partial degradation product of starch obtained in the step (a1); and a step (a3) for drying the water-soluble polymer in the presence of water at 70-180°C so as to achieve a solid content of 90% or more.
C08B 31/12 - Éthers contenant des radicaux alkyle ou cycloalkyle substitués par des hétéro-atomes
A61F 13/15 - Garnitures absorbantes, p. ex. serviettes ou tampons hygiéniques pour application externe ou interne au corpsMoyens pour les maintenir en place ou les fixerApplicateurs de tampons
A61F 13/53 - Garnitures absorbantes, p. ex. serviettes ou tampons hygiéniques pour application externe ou interne au corpsMoyens pour les maintenir en place ou les fixerApplicateurs de tampons caractérisées par le milieu absorbant
The object of the present invention is to provide a stabilizer for and a method for stabilizing an emulsion composition emulsified with a non-ionic surfactant. This invention solves the above object by providing a stabilizer for an emulsion composition emulsified with a non-ionic surfactant; the stabilizer comprising a glycosyl naringenin as an effective ingredient, and a method for stabilizing an emulsion composition emulsified with a non-ionic surfactant; the method comprising a step of having a stabilizer that comprises a glycosyl naringenin as an active ingredient mixed and/or contained in a starting material of the emulsion composition, an intermediate product of the emulsion composition, and/or the emulsion composition manufactured.
The present invention aims to provide a saccharide composition suitable for a cyclic-tetrasaccharide-containing starch syrup which has low viscosity, low water activity, low coloration property, and low calorie content, and which is unlikely to cause precipitation of crystals of saccharides during storage, and to provide a use of the composition and a production method for the composition. The object is achieved by providing a cyclic-tetrasaccharide-containing saccharide composition having the following characteristics (1) to (3): (1) the saccharide composition includes a branched cyclic tetrasaccharide in addition to the cyclic tetrasaccharide, wherein the content of the cyclic tetrasaccharide with respect to the total solid content of the saccharide composition obtained by allowing glucoamylase and α-glucosidase to act on the above saccharide composition is 38% by mass or higher, on a dry solid basis; (2) the ratio of α-1,4-linked glucose in the total glucose residues constituting the saccharide composition in methylation analysis is over 9% and 15% or lower, and (3) the ratio of α-1,4,6-linked glucose in the total glucose residues constituting the saccharide composition in methylation analysis is less than 6%; and providing a use of the composition and a production method for the composition.
C12P 19/16 - Préparation de composés contenant des radicaux saccharide préparés par action d'une alpha-1, 6 glucosidase, p. ex. amylose, amylopectine déramifiée
C12N 9/44 - Hydrolases (3.) agissant sur les composés glycosyliques (3.2) agissant sur les liaisons alpha-glucosidiques-1, 6, p. ex. iso-amylase, pullulanase
C12P 19/14 - Préparation de composés contenant des radicaux saccharide préparés par action d'une carbohydrase, p. ex. par action de l'alpha-amylase
A23L 29/30 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des sirops d'hydrate de carboneAliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des sucresAliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des alcools de sucre, p. ex. du xylitolAliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des hydrolysats d'amidon, p. ex. de la dextrine
C07H 3/06 - Oligosaccharides, c.-à-d. saccharides comportant de trois à cinq radicaux saccharide liés entre eux par des liaisons glucosidiques
12.
COMPOSITION FOR ENHANCING SALTINESS, COMPOSITION FOR ORAL USE, AND METHOD FOR ENHANCING SALTINESS THEREOF
The purpose of the present invention is to provide a novel means for enhancing the saltiness of a composition for oral use. Provided is a composition for oral use the saltiness of which can be enhanced by using glucosyl naringin.
A23L 27/00 - ÉpicesAgents aromatiques ou condimentsÉdulcorants artificielsSels de tableSubstituts diététiques du selLeur préparation ou leur traitement
Public University Corporation Nagoya City University (Japon)
Hayashibara Co., Ltd. (Japon)
Inventeur(s)
Inagaki, Hiroshi
Takase, Hiroshi
Kusano, Hajime
Nagaike, Hiroshi
Ariyasu, Toshio
Abrégé
A staining method includes staining a biological sample with a coumarin fluorescent dye to provide a fluorescent-stained sample, and bringing the fluorescent-stained sample into contact with osmium tetroxide, further embedding the sample in an epoxy resin, and subsequently slicing the sample to provide a section sample including the fluorescent-stained sample.
G01N 1/36 - Enrobage ou montage analogue d'échantillons
G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
The present invention addresses the problem of providing a solid food that contains a protein and that has both excellent texture and dietary fiber-containing characteristics. Said problem is solved by providing a solid food that contains: a cyclic tetrasaccharide represented by cyclo{→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→} and/or a glycosyl derivative thereof; and a protein.
The present invention addresses the problem of providing a composition capable of effectively promoting GLP-1 secretion. This problem can be solved by providing a composition for promoting GLP-1 secretion that comprises, as active ingredients, glycosylnaringenin as component (A) together with at least one selected from the group consisting of α-pinene, β-pinene, sabinene, camphene, valencene, β-caryophyllene, β-ionone, methyl anthranilate, methyl N-methylanthranilate, thymol and nootkatone, as component (B).
A61K 31/122 - Cétones ayant l'atome d'oxygène lié directement à un cycle, p. ex. quinones, vitamine K1, anthraline
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 1/04 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des ulcères, des gastrites ou des œsophagites par reflux, p. ex. antiacides, antisécrétoires, protecteurs de la muqueuse
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
C12G 3/05 - Préparation d'autres boissons alcoolisées par mélange, p. ex. pour la préparation de liqueurs avec des ingrédients améliorant la santé, p. ex. des flavonoïdes, des flavones, des polyphénols ou des polysaccharides
The present invention provides a water-absorbent resin having excellent water-absorbing performance and water-retaining performance and high production efficiency. The present invention relates to a water-absorbent resin including a crosslinked product of a water-soluble polymer obtained by introducing an acidic group into a partial decomposition product of starch having a weight average molecular weight of 7.5 million or less.
The present invention provides a method for highly efficiently producing a water-soluble polymer and a method for producing a water-absorbing resin having excellent ability to absorb water. The method for producing a water-soluble polymer comprises step (a1) in which starch is reduced in molecular weight to thereby obtain a partial-starch-decomposition product and step (a2) in which an ionic functional group is introduced into the partial-starch-decomposition product obtained in the step (a1).
The present invention provides a water-absorbing resin that has excellent water-absorbing performance and that easily degrades. The present invention relates to a water-absorbing resin: which is a crosslinked product of a glucose polymer having an acidic group introduced to starch or a starch partial decomposition product; and which forms a physical gel by absorbing water.
The present invention addresses the problem of providing a new enzyme that specifically hydrolyzes an α-1,2-glucoside bond, and a production method therefor. The above problem is solved by providing an α-1,2-glucosidase which has activity to specifically hydrolyze an α-1,2-glucoside bond in an α-1,2-glucooligosaccharide having a glucose polymerization degree of 2-5 and generate D-glucose, and a production method therefor.
A problem addressed is to provide a new composition for hair setting having adequate hair setting power and a means for realizing such a composition for hair setting. The problem is solved by providing a hair setting power enhancer having isomaltooligosaccharide as an active ingredient and a composition for hair setting containing the same.
The present invention addresses the problem of providing a gel-type skin external composition containing a L-ascorbic acid derivative, which has excellent shape retention, stability, and excellent feeling of use even when salts coexist in the composition. The above problem is solved by providing a gel-type skin external composition containing a L-ascorbic acid derivative, a nonionic synthetic water-soluble polymer, and a natural water-soluble polysaccharide.
The present invention addresses the problem of providing a means to make it possible to improve intestinal flora of livestock and/or poultry and also improve productivity, and in particular, to increase the weight of the livestock and/or poultry and improve the feed requirement rate and uniformity thereof. This problem is overcome by providing: a method for improving the productivity of livestock and/or poultry and a method for improving the intestinal flora of livestock and/or poultry by feeding the livestock and/or poultry a feed containing trehalose and a probiotic; and a trehalose- and probiotic-containing feed for livestock and/or poultry.
A23K 10/18 - Ajout de micro-organismes ou de leurs produits d’extraction, p. ex. de protéines provenant d’organismes unicellulaires, à des compositions de produits alimentaires de micro-organismes vivants
The present invention addresses the problem of providing a novel crystalline lens hardness adjustment agent that can be easily, simply, and safely ingested over an extended period of time, and that can effectively adjust the hardness of crystalline lenses and can prevent, alleviate, and improve deterioration of near vision and focus adjustment failure as seen in presbyopia caused by aging and various diseases. Said problem is solved by providing a crystalline lens hardness adjustment agent containing glucosyl hesperidin as an active ingredient.
A61P 27/10 - Agents ophtalmiques pour le traitement des troubles d'accommodation, p. ex. myopie
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
The present invention addresses the problem of providing a novel heat stress relieving agent that can be taken easily, conveniently and safely even by infants and the elderly, who are susceptible to heat stress such as heat illness, that rapidly promotes sweating in a heat stress environment, and that prevents, alleviates, or improves symptoms and disorders caused by heat stress, such as heat illness. The above problem is solved by providing a heat stress relieving agent containing glycosyl hesperetin as an effective ingredient, and a basal body temperature maintaining agent containing glycosyl hesperetin as an effective ingredient.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 29/02 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS] sans effet anti-inflammatoire
The present invention addresses the problem of providing an orally-administrable anti-neurodegenerative disease agent having an action of accelerating neurocyte growth and an action of promoting neurite-outgrowth, and having excellent transfer properties to central nervous tissues. The problem is solved by providing an anti-neurodegenerative disease agent containing a compound represented by General formula 4 as an active ingredient, and having an action of accelerating neurocyte growth, an action of promoting neurite-outgrowth, and an action of scavenging reactive oxygen species. In General formula 4, R10 and R11 represent the same or different alkyl group having 2-8 carbon atoms, and the alkyl group may be either a straight chain or a branched chain. n represents an integer of 0 or 1, and X4− represents a suitable counter anion that is pharmaceutically acceptable.
The present invention addresses the problem of providing: an enzyme useful for the production of isomaltose or isomalto-oligosaccharide; and a method for efficiently producing isomaltose or isomalto-oligosaccharide using the enzyme. The problem can be solved by providing: a panose-degrading enzyme having the below-mentioned substrate specificity properties (1) and (2), and a method for producing the enzyme; a microorganism capable of producing the enzyme; DNA encoding the enzyme, and recombinant DNA and a transformant each harboring the DNA; and a method for producing isomaltose or a method for producing isomalto-oligosaccharide, in which the enzyme is utilized. (1) The enzyme can hydrolyze panose to produce isomaltose and D-glucose; and (2) the enzyme cannot react with isomaltotriose, dextran and pullulan.
PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY (Japon)
HAYASHIBARA CO., LTD. (Japon)
Inventeur(s)
Inagaki Hiroshi
Takase Hiroshi
Kusano Hajime
Nagaike Hiroshi
Ariyasu Toshio
Abrégé
A staining method that comprises staining a biological sample with a coumarin fluorescent dye to give a fluorescent-stained sample, bringing the fluorescent-stained sample into contact with osmium tetroxide, then embedding the sample in an epoxy resin and slicing the same to give a slice sample containing the fluorescent-stained sample.
C12Q 1/28 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une oxydoréductase une peroxydase
G01N 1/28 - Préparation d'échantillons pour l'analyse
G01N 1/36 - Enrobage ou montage analogue d'échantillons
G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres
G01N 33/536 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec formation d'un complexe immunologique en phase liquide
G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
The present invention addresses the problem of providing a stabilizer and a stabilization method for an emulsion composition obtained by emulsification with a nonionic surfactant. The problem is solved by providing: a stabilizer for an emulsion composition obtained by emulsification with a nonionic surfactant, the stabilizer containing glycosyl naringenin as an active ingredient; and a stabilization method for an emulsion composition obtained by emulsification with a nonionic surfactant, the method including a step in which the stabilizer containing glycosyl naringenin as an active ingredient is mixed with and/or incorporated into a raw material for the emulsion composition, an intermediate thereof, and/or the produced emulsion composition.
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
29.
AGENT FOR IMPROVING CUTANEOUS RESIDENT FLORA BALANCE
The present invention addresses the problem of providing a composition for external use on the skin that suppresses a reduction in diversity of cutaneous resident flora and maintains a good skin environment. The present invention solves the problem by providing an agent for improving the balance of cutaneous resident flora, the agent containing lactosucrose as an active ingredient.
The present invention addresses the problem of providing: a sugar composition suitable for a cyclic tetrasaccharide-containing starch syrup which has low viscosity, low water activity, and low colorability, which is low in calories, and which is not prone to deposition of sugar crystals during storage; the use thereof; and a production method therefor. The problem is solved by providing: a sugar composition that contains cyclic tetrasaccharide; the use thereof; and a production method therefor, wherein the sugar composition has the following features (1) to (3): (1) when the sugar composition contains branched cyclic tetrasaccharide in addition to the cyclic tetrasaccharide, and glucoamylase and α-glucosidase are caused to act on the sugar composition, the cyclic tetrasaccharide content, based on anhydride content, is not less than 38 mass% of all solids in the resulting sugar composition; (2) α-1,4-linked glucose accounts for more than 9% and not more than 15% of all glucose residues of the sugar composition according to methylation analysis; and (3) α-1,4,6-linked glucose accounts for less than 6% of all the glucose residues of the sugar composition according to methylation analysis.
C07H 3/06 - Oligosaccharides, c.-à-d. saccharides comportant de trois à cinq radicaux saccharide liés entre eux par des liaisons glucosidiques
C12P 19/18 - Préparation de composés contenant des radicaux saccharide préparés par action d'une transférase glycosylique, p. ex. alpha-, bêta- ou gamma-cyclodextrines
A23L 7/109 - Types de pâtes alimentaires, p. ex. macaroni ou nouilles
A23L 11/00 - Légumes secs, c.-à-d. fruits de plantes légumineuses, pour l'obtention d'alimentsProduits dérivés de légumineusesLeur préparation ou leur traitement
A23L 29/281 - Protéines, p. ex. gélatine ou collagène
A23L 29/30 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des sirops d'hydrate de carboneAliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des sucresAliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des alcools de sucre, p. ex. du xylitolAliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des hydrolysats d'amidon, p. ex. de la dextrine
A23L 33/21 - Adjonction de substances essentiellement non digestibles, p. ex. de fibres diététiques
A21D 13/80 - Pâtisserie non prévue ailleurs, p. ex. gâteaux ou biscuits
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A23G 3/34 - Sucreries, confiseries ou massepainProcédés pour leur fabrication
A23G 9/34 - Desserts glacés, p. ex. confiseries glacées, glacesMélanges correspondants caractérisés par la composition caractérisés par les hydrates de carbone utilisés, p. ex. des polysaccharides
The present invention relates to a compound represented by general formula (I). (In formula (I), X represents a methyl group or a halogen atom; each of R1to R14independently represents a hydrogen atom, a halogen atom, a cyano group, an optionally substituted alkyl group having 1 to 8 carbon atoms or an optionally substituted aromatic hydrocarbon group having 6 to 12 carbon atoms; Bm- represents a polyoxometalate anion; m represents an integer from 1 to 20; and n represents an integer from 1 to 20, provided that the value of n is determined so that the electrical charge of formula (I) as a whole becomes zero.)
C09B 23/04 - Colorants méthiniques ou polyméthiniques, p. ex. du type cyanine caractérisés par la chaîne méthinique contenant un nombre impair de groupes CH un seul groupe CH, p. ex. cyanines, isocyanines, pseudocyanines
32.
COMPOSITION FOR INHIBITING α-SYNUCLEIN AGGREGATION AND COMPOSITION FOR INHIBITING SPREADING OF α-SYNUCLEIN AGGREGATES
The present invention provides: a composition which is for inhibiting the spreading of α-synuclein aggregates and contains transglycosylation hesperidin as an active ingredient; a composition which is for preventing the progression of α-synucleinopathy and contains transglycosylation hesperidin as an active ingredient; a composition which is for inhibiting α-synuclein aggregation and contains transglycosylation hesperidin as an active ingredient; and a composition which is for preventing and/or alleviating α-synucleinopathy and contains transglycosylation hesperidin as an active ingredient.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
A61K 31/405 - Acides indole-alkanecarboxyliquesLeurs dérivés, p. ex. tryptophane, indométhacine
A61K 31/423 - Oxazoles condensés avec des carbocycles
A61K 31/4409 - Pyridines non condenséesLeurs dérivés hydrogénés substituées uniquement en position 4, p. ex. isoniazide, iproniazide
A61K 31/4453 - Pipéridines non condensées, p. ex. pipérocaïne substituées uniquement en position 1, p. ex. propipocaïne, dipérodone
A61K 31/4709 - Quinoléines non condensées contenant d'autres hétérocycles
A61K 31/7016 - Disaccharides, p. ex. lactose, lactulose
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
The purpose of the present invention is to provide a gel-type external composition for the skin which contains an L-ascorbic acid derivative and which, even when a salt is also present in the composition, has excellent shape retention, is stable, and feels good to use; this purpose is met by providing a gel-type external composition for the skin containing an L-ascorbic acid derivative, a nonionic synthetic water-soluble polymer, and a natural water-soluble polysaccharide.
A61K 8/81 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons insaturées carbone-carbone
34.
CRYSTAL OF POTASSIUM SALT OF 2-O-α-D-GLUCOSYL-L-ASCORBIC ACID AND PRODUCTION METHOD THEREFOR
The present invention addresses the problem of providing a novel crystal of 2-O-α-D-glucosyl-L-ascorbic acid and a method for producing the crystal. The problem is solved by providing a crystal of the potassium salt of 2-O-α-D-glucosyl-L-ascorbic acid and a method for producing said crystal.
A23C 9/13 - Préparations à base de lait fermentéTraitements utilisant des micro-organismes ou des enzymes comportant l'emploi d'additifs
C07H 17/04 - Radicaux hétérocycliques contenant uniquement des atomes d'oxygène comme hétéro-atomes du cycle
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
A61P 17/16 - Émollients ou protecteurs, p. ex. contre les radiations
A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
A61K 31/7012 - Composés ayant un groupe carboxyle libre ou estérifié, lié directement ou par une chaîne carbonée, à un atome de carbone du radical saccharide, p. ex. acide glucuronique, acide neuraminique
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
30 - Aliments de base, thé, café, pâtisseries et confiseries
32 - Bières; boissons non alcoolisées
Produits et services
(1) Chemicals used in industry, science and photography, namely, chemical additives for use in the manufacture of cosmetics, chemical additives for use in the manufacture of food, chemical additives for use in the manufacture of pharmaceuticals, chemical agents for use in the manufacture of dyestuffs, chemicals for use in the manufacture of adhesives, chemical coatings for preserving foodstuffs; chemicals for use in agriculture, horticulture and forestry, except fungicides, herbicides, insecticides and parasiticides, namely, soil amendments for agricultural, horticultural and forestry purposes; unprocessed artificial resins, unprocessed plastics; manures; fire extinguishing compositions; tempering and soldering preparations; chemical substances for preserving foodstuffs; tanning substances, namely, leather tanning agents, oils for tanning leather, substances for tanning animal skins and hides; adhesives used in industry, namely, general use adhesives; chemicals, namely, chemical additives for use in the manufacture of food, chemicals for use in the processing of plastics, chemical stabilizers for preserving foodstuffs, emulsifiers for use in the manufacture of food, chemical additives for use in the manufacture of pharmaceuticals, chemical agents for manufacturing dyestuffs, chemical additives for use in the manufacture of animal foodstuffs; glucosides; plant polyphenols for use as a raw material in the manufacture of foods, beverages and dietary supplements for humans and animals; flavonoids derived from plant extracts for use in the manufacture of pharmaceuticals; flavonoids derived from plant extracts for use in the manufacture of food; chemical agents, namely, chemical agents for acid removal in industrial manufacturing applications, chemical agents for coating textiles, furs and leathers, as well as non-woven fabrics, chemical agents for manufacturing dyestuffs; plant growth regulating preparations; artificial sweeteners; flour for industrial purposes, namely, potato flour for industrial purposes, pulse flour for industrial purposes, wood flour for use as a filler in the manufacture of plastics; starch for industrial purposes, namely, potato starch for industrial purposes, potato starch for the food industry, starch for manufacturing washing preparations, starch for use in the manufacture of paper or textiles, starch paste for industrial purposes.
(2) Pharmaceutical, veterinary and sanitary preparations, namely, adhesive bandages for skin wounds, anti-aging medicated skin care preparations, antibacterial skin soaps, herbal sore skin ointments, medicated cleansers for skin and wounds, pharmaceutical preparations for treating and preventing skin and nail diseases, skin care preparations for therapeutic purposes, pharmaceutical preparations for the treatment of eye diseases and conditions, pharmaceutical preparations for the treatment of cancer, pharmaceutical preparations for the treatment of diabetes, pharmaceutical preparations for the treatment of allergies; dietetic substances adapted for medical use, namely, food for babies; plasters, materials for dressings; material for stopping teeth, dental wax; all purpose disinfectants; preparations for destroying vermin; fungicides, herbicides; flavonoids for use as a dietary supplement for general health and well being; reagent paper for medical purposes; dental materials, namely, dental abrasives, dental impression materials, dental resin for temporary bridges, crowns and veneers; dietary and nutritional supplements for general health and well-being; dietary supplements for humans for general health and well-being; protein powder dietary and nutritional supplements; dietary and nutritional supplements containing protein for general health and well-being; dietary and nutritional supplements containing collagen for general health and well-being; dietary and nutritional supplements containing amino acid for general health and well-being; dietary and nutritional supplements containing mineral; dietary and nutritional supplements containing iron; dietary and nutritional supplements for animals to promote energy and healthy fur, paws, and claws, and for general health and well-being; lacteal flour for babies; dietetic beverages adapted for medical purposes, namely, dietetic fruit juice beverages adapted for medical purposes, dietetic beverages for babies adapted for medical purposes; beverages for babies; excipients for use in the manufacture of pharmaceutical preparations and veterinary preparations, namely, excipients for use in pharmaceuticals to treat cancer, diabetes, allergies and eye diseases; dietary and nutritional supplement drink mixes for general health and well-being; powdered dietary and nutritional supplement drink mixes for general health and well-being and for the prevention and treatment of digestive diseases and disorders.
(3) Binding agents for ice cream; meat tenderizers for household purposes; preparations for stiffening whipped cream; aromatic preparations for food, not from essential oils, namely, aromatic preparations for candies, aromatic preparations for ice-creams, aromatic preparations for chocolate , aromatic preparations for fruit jellies, and aromatic teas, other than for medicinal use; tea; tea-based beverages; roasted, powdered and granulated coffee for drinks; coffee-based beverages; prepared cocoa and cocoa-based beverages; chocolate-based beverages; confectionery, namely, fruit confectionery, sugar confectionery, chocolate confectionery; candy; cookies; confectionery fruit jellies; ice cream; biscuits; pound cake; chocolate; gum sweets, namely, gummy candies, bubble gum; gelatin-based chewy candies; confectionery in the form of tablets, namely, candy, pastilles and non-medicated lozenges; soda pop flavored candy; grain-based snack foods; japanese rice cake stuffed with sweetened bean jam; sweetened red bean jam; bread and buns; sandwiches; steamed buns stuffed with minced meat [Chuka-manjuh]; hamburger sandwiches; pizzas; hot dog sandwiches; meat pies; seasonings [other than spices]; salad dressings; sauces being condiments, namely, ketchup, mayonnaise, chili sauces, curry sauce, gravy sauces, hot sauces, oyster sauce, ponzu sauce, sauces for meat, soy sauce, teriyaki sauce, vegetable sauces; garden herbs, preserved [seasonings]; ice cream mixes; sherbet mixes; cereal preparations, namely, cereal-based snack food, ready-to-eat cereals, cereal bars, high-protein cereal bars and cereal based energy bars; instant noodles; chocolate spread; chinese stuffed dumplings [Gyoza, cooked]; chinese steamed dumplings [Shumai, cooked]; sushi; fried balls of batter mix with small pieces of octopus [Takoyaki]; pre-packed boxed lunches consisting primarily of rice, and also including meat, fish or vegetables; ravioli; instant confectionery mixes, namely, sherbet mixes, mixes for making croissants, hotcake mixes, cake mixes, pancake mixes, biscuit mixes, icing mixes, brownie mixes, frosting mixes, frozen yogurt mixes, instant pudding mixes, instant doughnut mixes, muffin mixes, crepe mixes and cookie mixes; pasta sauce; flour; wafers; cereal bars; confectionary in the form of cereal bar and chocolate bar containing protein; crackers; nougat; granola.
(4) Mineral and aerated waters and other non-alcoholic drinks, namely, non-alcoholic malt drinks, club soda, non-alcoholic water-based beverages in the nature of sparkling water, carbonated water, seltzer water, soft drinks, sports drinks, energy drinks, fruit juices, whey beverages, and fruit-flavored beverages; fruit drinks and fruit juices; syrups and other preparations for making beverages namely, syrups for making non-alcoholic beverages, powders used in the preparation of fruit-based beverages, powders used in the preparation of soft drinks, powders used in the preparation of sports drinks, concentrates and powders used in the preparation of energy drinks and fruit-flavored beverages; soft drinks; vegetable juices [beverages]; whey beverages; non-alcoholic beer; soya-based beverages, other than milk substitutes; soft drink mixes; soft drink mixes containing collagen; soft drink mixes containing protein; carbonated beverages; smoothies; energy drinks; soft drinks containing collagen; soft drinks containing protein; protein-enriched sports beverages; green vegetable juices; green vegetable juice beverages; mixes for making green vegetable juices; green vegetable juice beverages mixes; beverages, namely, vitamin enhanced waters, drinking water, carbonated water, flavoured waters; flavored waters; beer.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
30 - Aliments de base, thé, café, pâtisseries et confiseries
32 - Bières; boissons non alcoolisées
Produits et services
(1) Chemicals used in industry, science and photography, namely, chemical additives for use in the manufacture of cosmetics, chemical additives for use in the manufacture of food, chemical additives for use in the manufacture of pharmaceuticals, chemical agents for use in the manufacture of dyestuffs, chemicals for use in the manufacture of adhesives, chemical coatings for preserving foodstuffs; chemicals for use in agriculture, horticulture and forestry, except fungicides, herbicides, insecticides and parasiticides, namely, soil amendments for agricultural, horticultural and forestry purposes; unprocessed artificial resins, unprocessed plastics; manures; fire extinguishing compositions; tempering and soldering preparations; chemical substances for preserving foodstuffs; tanning substances, namely, leather tanning agents, oils for tanning leather, substances for tanning animal skins and hides; adhesives used in industry, namely, general use adhesives; chemicals, namely, chemical additives for use in the manufacture of food, chemicals for use in the processing of plastics, chemical stabilizers for preserving foodstuffs, emulsifiers for use in the manufacture of food, chemical additives for use in the manufacture of pharmaceuticals, chemical agents for manufacturing dyestuffs, chemical additives for use in the manufacture of animal foodstuffs; glucosides; plant polyphenols for use as a raw material in the manufacture of foods, beverages and dietary supplements for humans and animals; flavonoids derived from plant extracts for use in the manufacture of pharmaceuticals; flavonoids derived from plant extracts for use in the manufacture of food; chemical agents, namely, chemical agents for acid removal in industrial manufacturing applications, chemical agents for coating textiles, furs and leathers, as well as non-woven fabrics, chemical agents for manufacturing dyestuffs; plant growth regulating preparations; artificial sweeteners; flour for industrial purposes, namely, potato flour for industrial purposes, pulse flour for industrial purposes, wood flour for use as a filler in the manufacture of plastics; starch for industrial purposes, namely, potato starch for industrial purposes, potato starch for the food industry, starch for manufacturing washing preparations, starch for use in the manufacture of paper or textiles, starch paste for industrial purposes.
(2) Pharmaceutical, veterinary and sanitary preparations, namely, adhesive bandages for skin wounds, anti-aging medicated skin care preparations, antibacterial skin soaps, herbal sore skin ointments, medicated cleansers for skin and wounds, pharmaceutical preparations for treating and preventing skin and nail diseases, skin care preparations for therapeutic purposes, pharmaceutical preparations for the treatment of eye diseases and conditions, pharmaceutical preparations for the treatment of cancer, pharmaceutical preparations for the treatment of diabetes, pharmaceutical preparations for the treatment of allergies; dietetic substances adapted for medical use, namely, food for babies; plasters, materials for dressings; material for stopping teeth, dental wax; all purpose disinfectants; preparations for destroying vermin; fungicides, herbicides; flavonoids for use as a dietary supplement for general health and well being; reagent paper for medical purposes; dental materials, namely, dental abrasives, dental impression materials, dental resin for temporary bridges, crowns and veneers; dietary and nutritional supplements for general health and well-being; dietary supplements for humans for general health and well-being; protein powder dietary and nutritional supplements; dietary and nutritional supplements containing protein for general health and well-being; dietary and nutritional supplements containing collagen for general health and well-being; dietary and nutritional supplements containing amino acid for general health and well-being; dietary and nutritional supplements containing mineral; dietary and nutritional supplements containing iron; dietary and nutritional supplements for animals to promote energy and healthy fur, paws, and claws, and for general health and well-being; lacteal flour for babies; dietetic beverages adapted for medical purposes, namely, dietetic fruit juice beverages adapted for medical purposes, dietetic beverages for babies adapted for medical purposes; beverages for babies; excipients for use in the manufacture of pharmaceutical preparations and veterinary preparations, namely, excipients for use in pharmaceuticals to treat cancer , diabetes, allergies and eye diseases; dietary and nutritional supplement drink mixes for general health and well-being; powdered dietary and nutritional supplement drink mixes for general health and well-being and for the prevention and treatment of digestive diseases and disorders.
(3) Binding agents for ice cream; meat tenderizers for household purposes; preparations for stiffening whipped cream; aromatic preparations for food, not from essential oils, namely, aromatic preparations for candies, aromatic preparations for ice-creams, aromatic preparations for chocolate , aromatic preparations for fruit jellies, and aromatic teas, other than for medicinal use; tea; tea-based beverages; roasted, powdered and granulated coffee for drinks; coffee-based beverages; prepared cocoa and cocoa-based beverages; chocolate-based beverages; confectionery, namely, fruit confectionery, sugar confectionery, chocolate confectionery; candy; cookies; confectionery fruit jellies; ice cream; biscuits; pound cake; chocolate; gum sweets, namely, gummy candies, bubble gum; gelatin-based chewy candies; confectionery in the form of tablets, namely, candy, pastilles and non-medicated lozenges; soda pop flavored candy; grain-based snack foods; japanese rice cake stuffed with sweetened bean jam; sweetened red bean jam; bread and buns; sandwiches; steamed buns stuffed with minced meat [Chuka-manjuh]; hamburger sandwiches; pizzas; hot dog sandwiches; meat pies; seasonings [other than spices]; salad dressings; sauces being condiments, namely, ketchup, mayonnaise, chili sauces, curry sauce, gravy sauces, hot sauces, oyster sauce, ponzu sauce, sauces for meat, soy sauce, teriyaki sauce, vegetable sauces; garden herbs, preserved [seasonings]; ice cream mixes; sherbet mixes; cereal preparations, namely, cereal-based snack food, ready-to-eat cereals, cereal bars, high-protein cereal bars and cereal based energy bars; instant noodles; chocolate spread; chinese stuffed dumplings [Gyoza, cooked]; chinese steamed dumplings [Shumai, cooked]; sushi; fried balls of batter mix with small pieces of octopus [Takoyaki]; pre-packed boxed lunches consisting primarily of rice, and also including meat, fish or vegetables; ravioli; instant confectionery mixes, namely, sherbet mixes, mixes for making croissants, hotcake mixes, cake mixes, pancake mixes, biscuit mixes, icing mixes, brownie mixes, frosting mixes, frozen yogurt mixes, instant pudding mixes, instant doughnut mixes, muffin mixes, crepe mixes and cookie mixes; pasta sauce; flour; wafers; cereal bars; confectionary in the form of cereal bar and chocolate bar containing protein; crackers; nougat; granola.
(4) Mineral and aerated waters and other non-alcoholic drinks, namely, non-alcoholic malt drinks, club soda, non-alcoholic water-based beverages in the nature of sparkling water, carbonated water, seltzer water, soft drinks, sports drinks, energy drinks, fruit juices, whey beverages, and fruit-flavored beverages; fruit drinks and fruit juices; syrups and other preparations for making beverages namely, syrups for making non-alcoholic beverages, powders used in the preparation of fruit-based beverages, powders used in the preparation of soft drinks, powders used in the preparation of sports drinks, concentrates and powders used in the preparation of energy drinks and fruit-flavored beverages; soft drinks; vegetable juices [beverages]; whey beverages; non-alcoholic beer; soya-based beverages, other than milk substitutes; soft drink mixes; soft drink mixes containing collagen; soft drink mixes containing protein; carbonated beverages; smoothies; energy drinks; soft drinks containing collagen; soft drinks containing protein; protein-enriched sports beverages; green vegetable juices; green vegetable juice beverages; mixes for making green vegetable juices; green vegetable juice beverages mixes; beverages, namely, vitamin enhanced waters, drinking water, carbonated water, flavoured waters; flavored waters; beer.
37.
CHOCOLATE PRODUCTION METHOD AND AGITATION MIXER USED THEREFOR
The present invention addresses the problem of providing: a chocolate production method that comprises a simplified and efficient step for enabling uniform dispersion of a powdery ingredient in a chocolate raw material; and an agitation mixer for use in said production method. This problem is solved by providing: a chocolate production method which comprises a step for agitating a melted chocolate raw material and a powdery ingredient in a decompressed atmosphere so as to disperse said ingredient in the chocolate raw material; and an agitation mixer for use in such a production method.
The present invention addresses the problem of providing a novel heat stress alleviation agent that can be taken simply, safely, and easily, even by infants and the elderly, who are susceptible to heat stress such as heatstroke, that rapidly promotes sweating in heat stress environments, and that prevents, alleviates, or improves symptoms and disorders caused by heat stress, such as heatstroke. Provided are: a heat stress alleviation agent that contains glycosyl hesperidin as an active ingredient; and a basal body temperature maintenance agent that contains glycosyl hesperidin as an active ingredient.
A23C 9/13 - Préparations à base de lait fermentéTraitements utilisant des micro-organismes ou des enzymes comportant l'emploi d'additifs
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 39/00 - Agents protecteurs généraux ou antipoisons
A23L 29/281 - Protéines, p. ex. gélatine ou collagène
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A23G 3/34 - Sucreries, confiseries ou massepainProcédés pour leur fabrication
A23G 4/12 - Chewing-gum caractérisé par la composition contenant des micro-organismes ou des enzymesChewing-gum caractérisé par la composition contenant des agents paramédicaux ou diététiques, p. ex. des vitamines
The present invention addresses the problem of providing: a novel cyclic saccharide comprising D-glucose as a constituent sugar; a novel enzyme for producing the cyclic saccharide; and production methods and uses thereof. Said problem is solved by providing: a cycloisomaltotetraose having a structure in which four molecules of D-glucose are linked in a cyclic form through an α-1,6-glucoside bond; a cycloisomaltotetraose production enzyme; a DNA that encodes said enzyme; and production methods and uses thereof.
C12P 19/18 - Préparation de composés contenant des radicaux saccharide préparés par action d'une transférase glycosylique, p. ex. alpha-, bêta- ou gamma-cyclodextrines
A23L 33/125 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sirops d'hydrate de carboneModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sucresModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des alcools de sucreModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des hydrolysats d'amidon
1255 represent H or an arbitrary organic group; and X-10111414 represent H or an arbitrary organic group; X- represents an arbitrary counter anion; and each part shown in a dotted line represents a condensed ring, or H or arbitrary independent organic groups bonded to the 5- and 6-positions of the thiopyran ring, provided that a halogen atom is not directly bonded to the meso position of the polymethine chain.)
A61K 31/4709 - Quinoléines non condensées contenant d'autres hétérocycles
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (Japon)
HAYASHIBARA CO., LTD. (Japon)
Inventeur(s)
Omachi Haruka
Shinohara Hisanori
Watanabe Hikaru
Abrégé
[Problem] To lower the cost in a separation method that separates semiconducting carbon nanotubes from carbon nanotubes in which metal and semiconducting carbon nanotubes are mixed. [Solution] A method for separating semiconducting carbon nanotubes, the method being one in which: a first substance, a second substance that separates into two phases when mixed with the first substance in a state of solution, sodium dodecyl sulfate, sodium cholate, and carbon nanotubes in which a mixture of metal and semiconducting carbon nanotubes are present are mixed with a solvent to produce a dispersion; the dispersion is separated into a first layer containing mainly the first substance and a second layer containing mainly the second substance; and the semiconducting carbon nanotubes are moved to either the first layer or the second layer, wherein the method is characterized in that the first substance is an α-glucan in which glucose is linked by α-glucoside bonds, the weight-average molecular weight Mw is 4000-7000, and the ratio of α-1,6 bonded glucose residues to total glucose residues is 40-70%.
The present invention addresses the problem of providing a syneresis inhibitor that can be safely and advantageously used in fields such as foods, cosmetics, quasi drugs, drugs and industrial products, and the use thereof. The problem is solved by providing: a syneresis inhibitor containing, as an active ingredient, a branched α-glucan mixture which contains glucose as a constituent sugar, has a branched structure of a glucose polymerization degree of 1 or higher that is bonded, via a bond other than an α-1,4 bond, to a non-reducing terminal glucose residue positioned at one end of a linear glucan bonded via an α-1,4 bond and having a glucose polymerization degree of 3 or higher and, when digested by isomaltodextranase, generates 25-50% by mass of isomaltose relative to solid digested products, and in which the ratio of glucose residues bonded via an α-1,4 bond and glucose residues bonded via an α-1,6 bond is within the range of 1:0.6 to 1:4 and the total of the two types of residues constitutes 60% or more of the total glucose residues; and the use the syneresis inhibitor.
A23L 29/00 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement
A23G 9/34 - Desserts glacés, p. ex. confiseries glacées, glacesMélanges correspondants caractérisés par la composition caractérisés par les hydrates de carbone utilisés, p. ex. des polysaccharides
A23L 29/256 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des agents gélifiants ou épaississants d'origine végétale à base d'algues, p. ex. alginates, agar-agar ou carraghénane
The present invention addresses the problem of providing a binder, a bound and shaped food, and a method for producing the bound and shaped food, and solves this problem by providing: a binder which contains, as active ingredients, pullulan, a branched α-glucan mixture having the characteristics (A) to (C), and an oligosaccharide, the contained amount of the pullulan per solid content of the binder being 10-50 mass%; a bound and shaped food obtained by binding and shaping by use of the binder; and a method for producing the bound and shaped food. (A) Glucose is used as a constituent sugar. (B) Included is a branched structure having a glucose polymerization degree of 1 or higher, the branched structure being linked, via a bond other than an α-1,4 bond, to a non-reduction terminal glucose residue positioned at one end of a linear glucan that is linked via α-1,4 bonds and that has a glucose polymerization degree of 3 or higher. (C) Isomaltose is produced, through isomaltodextranase digestion, in an amount of 5 mass% or more per solid content of the digest.
A23L 29/269 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des agents gélifiants ou épaississants d'origine microbienne, p. ex. xanthane ou dextrane
A23G 3/00 - SucreriesConfiseriesMassepainProduits enrobés ou fourrés
A23L 5/00 - Préparation ou traitement des aliments ou produits alimentaires en généralAliments ou produits alimentaires ainsi obtenusLeurs matériaux
A23L 7/126 - En-cas ou similaires obtenus par amalgame, façonnage ou compactage de céréales ou de morceaux de céréales, p. ex. barres de céréales
A23L 29/00 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement
The present invention addresses the problem of providing: an in vivo phenol compound reducing agent; and a food or beverage for reducing an in vivo phenol compound, which contains the in vivo phenol compound reducing agent. The problem can be solved by providing: an in vivo phenol compound reducing agent containing a branched α-glucan mixture having the characteristic properties (A) to (C) mentioned below as an active ingredient; and a food or beverage for reducing an in vivo phenol compound, which contains the in vivo phenol compound reducing agent: (A) glucose is contained as a constituent sugar; (B) a branched structure having a glucose polymerization degree of 1 or more is linked to a non-reducing-terminal glucose residue located at one end of a linear glucan via a bond other than an α-1,4 bond, wherein the linear glucan is composed of glucose molecules linked together via an α-1,4 bond at a polymerization degree of 3 or more; and (C) isomaltose is produced by the digestion with isomaltodextranase.
The present invention addresses the problem of providing: a quality improver which has a proper molecular weight, a proper viscosity and solubility in cold water and can be used advantageously in the fields of foods, cosmetics, quasi drugs, drugs, industrial products, etc.; and a use of the quality improver. The problem can be solved by: a quality improver which can be produced by a production method involving a step of gelatinizing a waxy starch and then allowing an amylase to act on a gelatinized product to liquefy the gelatinized product and a step of allowing an α-glucosyltransferase to act on a liquefied product, and which contains an α-glucan mixture having the below-mentioned characteristic properties as an active ingredient; and a use of the quality improver: (1) the weight average molecular weight (Mw) falls within the range from 150 kDa to 3,000 kDa; (2) a value (Mw/Mn) obtained by dividing the weight average molecular weight (Mw) with a number average molecular weight (Mn) is 35.1 or less; and (3) an α-glucan molecule having an isomaltose structure at a non-reducing terminal is contained.
A23L 7/109 - Types de pâtes alimentaires, p. ex. macaroni ou nouilles
A23L 11/00 - Légumes secs, c.-à-d. fruits de plantes légumineuses, pour l'obtention d'alimentsProduits dérivés de légumineusesLeur préparation ou leur traitement
A23L 13/00 - Produits à base de viandeFarine de viandeLeur préparation et leur traitement
C08B 37/00 - Préparation des polysaccharides non prévus dans les groupes Leurs dérivés
C12P 19/18 - Préparation de composés contenant des radicaux saccharide préparés par action d'une transférase glycosylique, p. ex. alpha-, bêta- ou gamma-cyclodextrines
The present invention addresses the problem of improving the quality of bread by the action of an enzyme. The present invention provides a bread quality improving agent containing exomaltotetraohydrolase.
The present invention addresses the problem of providing an autophagy-inducing agent which comprises, as an active ingredient, a highly-safe natural material having a remarkable autophagy-inducing effect and which can be administered to a human safely and easily over a relatively long period. The problem is solved by providing an autophagy-inducing agent which comprises a cyclic glucooligosaccharide as an active ingredient, and the use thereof.
A23L 33/125 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sirops d'hydrate de carboneModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sucresModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des alcools de sucreModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des hydrolysats d'amidon
A61K 31/7016 - Disaccharides, p. ex. lactose, lactulose
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
A61Q 19/00 - Préparations pour les soins de la peau
49.
POLYVINYL ALCOHOL-DEGRADING ENZYME AND PRODUCTION METHOD THEREFOR
The present invention addresses the problem of providing: a novel PVA-degrading enzyme, the identity of which is revealed at the amino acid sequence level; a production method therefor; DNA coding for the enzyme; and recombinant DNA and a transformant which contain the DNA. The problem is solved by providing a polyvinyl alcohol-degrading enzyme having features (1) to (3), a production method therefor, DNA coding for the enzyme, and recombinant DNA and a transformant which contain the DNA having: (1) an activity of oxidizing polyvinyl alcohol and producing hydrogen peroxide; (2) an activity of hydrolyzing a β-diketone; and (3) a molecular weight of 100,000 ± 20,000 as determined through SDS-polyacrylamide gel electrophoresis.
C12N 9/04 - Oxydoréductases (1.), p. ex. luciférase agissant sur des groupes CHOH comme donneurs, p. ex. oxydase de glucose, déshydrogénase lactique (1.1)
C12N 1/15 - ChampignonsLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12N 1/19 - LevuresLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12N 1/21 - BactériesLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
The present invention addresses the problem of providing a powdery plant extract for beverages having an excellent flavor-retention effect and high solubility. To solve this problem, provided is a powdery plant extract for beverages which comprises a drinkable plant extract and a branched α-glucan mixture, said branched α-glucan mixture having properties (A) to (C), at a ratio by mass in terms of solid of 1:0.1 to 1:20: (A) containing glucose as a constituting sugar; (B) having a branched structure with a glucose polymerization degree of 1 or greater that is connected, via a bond other than an α-1,4 bond, to a non-reducing terminal glucose residue positioned at an end of a linear glucan with a glucose polymerization degree of 3 or greater connected via an α-1,4 bond; and (C) when digested by isomaltodextranase, forming isomaltose in an amount of 5 mass% or more relative to solid digestion products.
The present invention addresses the problem of providing a binder, a bound and formed food, and a method for producing same, and solves this problem by providing: a binder that contains pullulan and a branched α-glucan mixture having the aforementioned characteristics (A) to (C) at quantities whereby the [pullulan / branched α-glucan mixture] mass ratio is within the range of 1.5-4 in terms of anhydride; a bound and formed food; and a method for producing same. (A) Glucose is used as a constituent sugar. (B) Included is a branched structure having a glucose polymerization degree of 1 or higher, the branched structure being linked, via a bond other than an α-1,4 bond, to a non-reducing terminal glucose residue positioned at one end of a linear glucan that is linked via an α-1,4 bond and has a glucose polymerization degree of 3 or higher. (C) Isomaltose is produced by isomaltodextranase digestion, the isomaltose being formed in an amount of 5 mass% or more relative to the solids of the product of digestion.
A23L 5/00 - Préparation ou traitement des aliments ou produits alimentaires en généralAliments ou produits alimentaires ainsi obtenusLeurs matériaux
A21D 13/80 - Pâtisserie non prévue ailleurs, p. ex. gâteaux ou biscuits
A23G 3/50 - Sucreries, confiseries ou massepainProcédés pour leur fabrication caractérisés par la forme, la structure ou la forme physique, p. ex. produits avec structure supportée
A23L 19/00 - Produits à base de fruits ou de légumesLeur préparation ou leur traitement
C08L 5/00 - Compositions contenant des polysaccharides ou leurs dérivés non prévus dans les groupes ou
52.
METHOD FOR PRODUCING FUMARIC ACID POWDER FORMULATION
The present invention addresses the problem of providing a fumaric acid powder formulation which is excellent in powder flow property and rate of dissolution. To solve this problem, the present invention provides a fumaric acid powder formulation and a method for producing the same, wherein the fumaric acid powder formulation is characterized by: containing a fumaric acid, a hydrophilic non-ionic surfactant, and a non-reducing disaccharide or a sugar alcohol containing two or less sugars, the percent by mass thereof with respect to the fumaric acid being at least 0.5 but less than 10 in terms of anhydrous content; and in that the fumaric acid is coated with the hydrophilic non-ionic surfactant and the non-reducing disaccharide or the sugar alcohol containing two or less sugars.
A23L 27/00 - ÉpicesAgents aromatiques ou condimentsÉdulcorants artificielsSels de tableSubstituts diététiques du selLeur préparation ou leur traitement
A23B 7/10 - Conservation au moyen d'acidesFermentation acide
A23L 3/3508 - Composés organiques contenant de l'oxygène contenant des groupes carboxyle
C11D 3/20 - Composés organiques contenant de l'oxygène
53.
Α,Α-TREHALOSE DIHYDRATE CRYSTAL-CONTAINING POWDER, METHOD FOR PRODUCING SAME, AND USE OF SAME
The problem is to provide an α,α-trehalose dihydrate crystal-containing powder having excellent emulsifying capacity; and the problem is solved by providing an α,α-trehalose dihydrate crystal-containing powder comprising particles containing α,α-trehalose and maltose and/or maltotriose, wherein the α,α-trehalose dihydrate crystal-containing powder contains 70-90 mass% of α,α-trehalose in terms of anhydride and contains a total of 3 mass% or more of maltose and/or maltotriose in terms of anhydride, and the degree of crystallization of the α,α-trehalose dihydrate crystals calculated on the basis of the powder x-ray diffraction profile is 25% to less than 90%.
A61K 47/14 - Esters d’acides carboxyliques, p. ex. acides gras monoglycérides, triglycérides à chaine moyenne, parabènes ou esters d’acide gras de PEG
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 47/44 - Huiles, graisses ou cires couvertes par plus d’un des groupes Huiles, graisses ou cires naturelles ou naturelles modifiées, p. ex. huile de ricin, huile de ricin polyéthoxylée, cire de lignite, lignite, gomme-laque, colophane, cire d’abeille ou lanoline
The problem is to provide a beer-flavored drink having improved foam characteristics. The problem is solved by providing: a beer-flavored drink characterized in containing at least 0.25 mass% of a branched α-glucan mixture that (A) has glucose as a constituent sugar, (B) has a branched structure having a glucose polymerization degree of 1 or higher, the branched structure being linked, via a bond other than an α-1,4 bond, to a non-reducing terminal glucose residue positioned at one end of a linear glucan that is linked via an α-1,4 bond and has a glucose polymerization degree of 3 or higher, (C) forms isomaltose by isomaltodextranase digestion, the isomaltose being formed in an amount of 25-50 mass% relative to the solids of the product of digestion, and (D) has a water-soluble dietary fiber content of 40 mass% or higher as determined by high-performance liquid chromatography (enzyme-HPLC); and a method for producing the beer-flavored drink.
The present invention addresses the problem of providing: an α-glucan mixture having an appropriate range of molecular weight, wherein when the α-glucan mixture is molded into an edible film, the resulting film is transparent and has exceptional strength and water-solubility even when no plasticizer is added thereto; and an application for said α-glucan mixture. The present invention overcomes the problem by providing: an α-glucan mixture obtained by a production method that comprises a step for gelatinizing a waxy starch and activating and liquefying an amylase, wherein the α-glucan mixture has features (1) and (2) described below; and an application for said α-glucan mixture: (1) The weight-average molecular weight (Mw) is within the range of 150-3,000 kDa; and (2) the value (Mw/Mn) obtained by dividing the weight-average molecular weight (Mw) by the number-average molecular weight (Mn) is 35.1 or less.
C12P 19/14 - Préparation de composés contenant des radicaux saccharide préparés par action d'une carbohydrase, p. ex. par action de l'alpha-amylase
A23L 5/00 - Préparation ou traitement des aliments ou produits alimentaires en généralAliments ou produits alimentaires ainsi obtenusLeurs matériaux
A23L 29/00 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement
A23L 29/20 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement contenant des agents gélifiants ou épaississants
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
C08B 37/00 - Préparation des polysaccharides non prévus dans les groupes Leurs dérivés
C08L 3/00 - Compositions contenant de l'amidon, de l'amylose ou de l'amylopectine ou leurs dérivés ou leurs produits de dégradation
C12P 19/18 - Préparation de composés contenant des radicaux saccharide préparés par action d'une transférase glycosylique, p. ex. alpha-, bêta- ou gamma-cyclodextrines
A23B 5/06 - Conservation des œufs ou de produits à base d'œufs en recouvrant les œufs d'une couche protectriceCompositions ou appareils à cet effet
A23L 7/109 - Types de pâtes alimentaires, p. ex. macaroni ou nouilles
56.
INHIBITOR FOR BLOOD GLUCOSE LEVEL INCREASE AND ORAL COMPOSITION COMPRISING SAME
The present invention addresses the problem of providing an inhibitor for blood glucose level increase, which can be daily, easily, safely and continuously taken after the intake of a monosaccharide by those who are worrying about blood glucose level including healthy persons, and an oral composition comprising the same. To solve this problem, provided are: an inhibitor for blood glucose level increase that comprises a branched α-glucan mixture characterized by (A) comprising glucose as a constituent sugar, (B) having a branched structure of a glucose polymerization degree of 1 or higher that is bonded, via a bond other than an α-1,4 bond, to a non-reducing terminal glucose residue positioned at one end of a linear glucan bonded via an α-1,4 bond and having a glucose polymerization degree of 3 or higher, and (C) forming isomaltose when digested by isomaltodextranase; and an oral composition that comprises the inhibitor for blood glucose level increase together with a monosaccharide.
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
57.
EXTERNAL PREPARATION FOR SKIN FOR REDUCING SKIN YELLOWNESS
[Problem] To provide an external preparation for the skin for reducing the yellowness of the skin which has already yellowed. [Solution] An external preparation for the skin for reducing the yellowness of the skin which has already yellowed, said preparation comprising hesperetin and/or glycosyl hesperetin as an active ingredient.
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61K 31/19 - Acides carboxyliques, p. ex. acide valproïque
A61K 31/198 - Alpha-amino-acides, p. ex. alanine ou acide édétique [EDTA]
A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
A61K 31/702 - Oligosaccharides, c.-à-d. ayant trois à cinq radicaux saccharide liés les uns aux autres par des liaisons glycosidiques
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61Q 19/00 - Préparations pour les soins de la peau
The present invention aims to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as age-related or senescent wrinkles, fine wrinkles, saggings, spots, etc., as well as maintaining or enhancing the skin barrier functions. The object is solved by providing an external dermal agent for anti-ageing, which contains as an effective ingredient(s) one or more members selected from the group consisting of adenosine N1-oxide 5′-phosphate, analogs thereof, and their salts.
A01N 43/04 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome
A61K 31/70 - Hydrates de carboneSucresLeurs dérivés
A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
A61Q 19/08 - Préparations contre le vieillissement
A61K 8/44 - Acides aminocarboxyliques ou leurs dérivés, p. ex. acides aminocarboxyliques contenant du soufreLeurs sels, esters ou dérivés N-acylés
A61K 31/7076 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées contenant des purines, p. ex. adénosine, acide adénylique
A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
A61K 31/7064 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées
The present invention addresses the problem of providing a safe antinflammatory agent that is efficacious for ameliorating and improving inflammatory symptoms and for preventing and treating inflammatory diseases and has little side effects. Also, the present invention addresses the problem of providing a cosmetic, quasi-drug, food, drink and drug containing the aforesaid antinflammatory agent. To solve these problems, provided are an antinflammatory agent that comprises, as an active ingredient, a saccharide having a ketoaldohexose structure in a molecule and a cosmetic, quasi-drug, food, drink and drug containing the aforesaid antinflammatory agent.
A61K 31/70 - Hydrates de carboneSucresLeurs dérivés
A23L 33/125 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sirops d'hydrate de carboneModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sucresModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des alcools de sucreModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des hydrolysats d'amidon
A61K 31/7004 - Monosaccharides ayant uniquement des atomes de carbone, d'hydrogène et d'oxygène
A61K 31/7016 - Disaccharides, p. ex. lactose, lactulose
A61P 1/02 - Préparations stomatologiques, p. ex. médicaments pour le traitement des caries, des aphtes, des périodontites
A61P 1/04 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des ulcères, des gastrites ou des œsophagites par reflux, p. ex. antiacides, antisécrétoires, protecteurs de la muqueuse
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p. ex. arthrites, arthroses
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
[Problem] To provide an external preparation for the skin that can tighten the skin and lift up sagging skin, shows no stickiness and is highly compatible with the skin without giving any uncomfortable feeling to a user. [Solution] An external preparation for the skin comprising pullulan and an alkali-swelling polymer, characterized in that the ratio by mass of pullulan to the alkali-swelling polymer is 10 or greater.
A61K 8/39 - Dérivés contenant 2 à 10 groupes oxyalkylène
A61K 8/81 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons insaturées carbone-carbone
A61Q 19/00 - Préparations pour les soins de la peau
[Problem] To provide an immunomodulator, which can be orally ingested continuously in daily diet without a fear of side effects, and use of the same. [Solution] To solve the problem, provided is an immunomodulator comprising, as an active ingredient, a branched α-glucan mixture having characteristics (A) to (C): (A) having glucose as a constituting saccharide; (B) having a branched structure with a glucose polymerization degree of 1 or higher, said branched structure being bound, via a linkage other than an α-1,4 linkage, to the non-reducing end glucose residue positioned at one end of a linear glucan which has a glucose polymerization degree of 3 or higher and in which glucose molecules are linked together via α-1,4 linkages; and (C) forming isomaltose when digested by isomaltodextranase.
The present invention addresses the problem of providing a method for suppressing the aging of starch without changing any physical properties other than the aging properties of starch, more specifically, without greatly changing the structure of starch. The present invention solves the above problem by providing a method for suppressing the aging of starch characterized by causing a glycosyl trehalose producing enzyme to act on a starch that shows aging properties, and introducing a trehalose structure to a reducing terminal of the starch, thereby lessening the aging properties of the starch than before the introduction of the trehalose structure.
The present invention has an object to provide an effective and safe therapeutic agent for inflammatory diseases such as sepsis, hepatitis, and inflammatory bowel disease, and solves the above object by providing a therapeutic agent for inflammatory diseases containing adenosine N1-oxide or a derivative thereof as an effective ingredient.
A01N 43/04 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome
A61K 31/70 - Hydrates de carboneSucresLeurs dérivés
A61K 31/7076 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées contenant des purines, p. ex. adénosine, acide adénylique
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61K 31/7056 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à cinq chaînons avec l'azote comme hétéro-atome d'un cycle
A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
A61K 31/7064 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées
A61K 31/7052 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides
C07H 19/167 - Radicaux purine avec un ribosyle comme radical saccharide
C07H 19/067 - Radicaux pyrimidine avec un ribosyle comme radical saccharide
A61K 31/708 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées contenant des purines, p. ex. adénosine, acide adénylique ayant des groupes oxo liés directement au système cyclique purine, p. ex. guanosine, acide guanylique
The present invention addresses the problem of providing a simple and versatile method for stabilizing 2-O-α-D-glucosyl-L-ascorbic acid in an acidic aqueous medium. The problem is solved by providing a method for stabilizing 2-O-α-D-glucosyl-L-ascorbic acid in an acidic aqueous medium, said method characterized in that 2-O-α-D-glucosyl-L-ascorbic acid is made to coexist with one or more stabilizers selected from C4–6 sugar alcohols, glucosyl fructose and sugar alcohols thereof, sugar alcohols of gluco-trisaccharides, glycosyl-trehalose, derivatives of cinnamic acid, derivatives of gallic acid and catechin, tartaric acid and salts thereof, amino acids, and peptides.
A61K 8/44 - Acides aminocarboxyliques ou leurs dérivés, p. ex. acides aminocarboxyliques contenant du soufreLeurs sels, esters ou dérivés N-acylés
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
A61K 47/12 - Acides carboxyliquesLeurs sels ou anhydrides
A61K 47/18 - AminesAmidesUréesComposés d’ammonium quaternaireAcides aminésOligopeptides ayant jusqu’à cinq acides aminés
A61K 47/20 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant du soufre, p. ex. sulfoxyde de diméthyle [DMSO], docusate, laurylsulfate de sodium ou acides aminosulfoniques
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
A61Q 19/00 - Préparations pour les soins de la peau
C09K 15/06 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés organiques contenant de l'oxygène
C09K 15/08 - Compositions anti-oxydantesCompositions inhibant les modifications chimiques contenant des composés organiques contenant de l'oxygène contenant une fraction phénol ou quinone
The present invention addresses the problem of providing an oral beauty care agent for ameliorating skin yellowness or dullness, skin texture, and skin quality. The problem is solved by providing an oral beauty care agent for ameliorating skin yellow dullness, skin texture, and skin quality, said agent comprising glycosyl hesperetin as an active ingredient.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
The present invention addresses the problem of providing an anti-aging external skin preparation that prevents or improves problems with skin appearance such as aging, wrinkles due to aging, fine wrinkles, loose skin, and spots, and maintains or enhances skin barrier functions. The abovementioned problem is solved by providing an anti-aging external skin preparation containing, as an active ingredient, at least one substance selected from adenosine N1- oxide 5'-phosphate, and analogs and salts thereof.
A61K 8/44 - Acides aminocarboxyliques ou leurs dérivés, p. ex. acides aminocarboxyliques contenant du soufreLeurs sels, esters ou dérivés N-acylés
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
The present invention addresses the problem of providing a novel glucosyl hesperetin in which the unpleasant taste characteristic of conventional glucosyl hesperetin-containing products is significantly reduced, a method for manufacturing the same, and an application for the same. The problem is solved by providing a glucosyl hesperetin characterized by including substantially no furfural, and containing glucosyl hesperetin at a level of at least 90 mass% but less than 100 mass%, of the dry solids, a method for manufacturing the same, and an application for the same.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
The problem addressed by the present invention is to provide a 4G-α-glucosylrutin crystal, a 4G-α-glucosylrutin crystal-containing powder, an application of same as a drug starting material, and applications as a cosmetic product starting material and a food product starting material. The problem is solved by providing a 4G-α-glucosylrutin crystal configured from a ratio of one molecule of 4G-α-glucosylrutin, one molecule of ethanol, and 8 molecules of water.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61Q 19/00 - Préparations pour les soins de la peau
C30B 7/08 - Croissance des monocristaux à partir de solutions en utilisant des solvants liquides à la température ordinaire, p. ex. à partir de solutions aqueuses par refroidissement de la solution
The present invention addresses the problem of providing an agent for lifestyle-related disease, an oral composition, and a high-fat food product that can be conveniently, safely, and continuously consumed on a daily basis. This problem is solved by an agent for lifestyle-related disease that contains a specific branched α-glucan having the characteristics described in the present invention, an oral composition comprising the agent, and a high-fat food product comprising the same.
A23L 1/30 - contenant des additifs (A23L 1/308 a priorité);;
A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme
70.
SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR
The purpose of the present invention is to provide a skin-exterior anti-ageing composition for preventing or improving trouble areas upon the exterior of the skin caused by ageing and degradation such as wrinkles, fine lines, blotches, and sagging. Accordingly, provided is a skin-exterior anti-ageing composition in which an aqueous medium is used as a base, and one or more selected from among L-ascorbic acid, derivatives thereof, and salts of the L-ascorbic acid and the derivatives thereof is included as an active ingredient.
A61K 8/97 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base d’algues, de champignons, de lichens ou de plantesCosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de leurs dérivés
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins
A61P 15/00 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs
A61P 27/12 - Agents ophtalmiques pour le traitement de la cataracte
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
The purpose of the present invention is to provide a skin-exterior anti-ageing composition for preventing or improving trouble areas upon the exterior of the skin caused by ageing and degradation such as wrinkles, fine lines, blotches, and sagging, and for maintaining or enhancing the barrier function and hyaluronic acid production of the skin. Accordingly, provided is a skin-exterior anti-ageing composition in which an aqueous medium is used as a base, and one or more selected from among L-ascorbic acid, derivatives thereof, and salts of the L-ascorbic acid and the derivatives thereof is included as an active ingredient.
A61K 8/97 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base d’algues, de champignons, de lichens ou de plantesCosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de leurs dérivés
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins
A61P 15/00 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 27/12 - Agents ophtalmiques pour le traitement de la cataracte
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
The present invention has an object to provide an external dermal agent with a sustainable anti-wrinkle action, which has both the action of enhancing the proliferation and differentiation of keratinocytes in the skin and the action of enhancing the collagen production in the skin, and which assists the maintenance and the improvement of tissue structures and physiological functions of the epidermis and the dermis, whereby providing a remarkable skin improvement effect. The present invention solves the above object by providing an external dermal agent containing α-D-glucopyranosyl-(1→3′)-adenosine and/or α-D-glucopyranosyl-(1→5′)-adenosine as an effective ingredient(s).
C07H 19/167 - Radicaux purine avec un ribosyle comme radical saccharide
A61Q 19/08 - Préparations contre le vieillissement
A61Q 19/00 - Préparations pour les soins de la peau
A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
C12P 19/18 - Préparation de composés contenant des radicaux saccharide préparés par action d'une transférase glycosylique, p. ex. alpha-, bêta- ou gamma-cyclodextrines
C12P 19/40 - Nucléosides avec un système cyclique condensé, contenant un cycle à six chaînons, comportant deux atomes d'azote dans le même cycle, p. ex. nucléosides puriques
73.
CRYSTALS OF 5'-O-α-D-GLUCOPYRANOSYLADENOSINE HYDROCHLORIDE AND USE THEREOF
The problem is to provide novel crystals of 5'-glucosyl adenosine the crystal structure of which has been elucidated, a 5'-glucosyl adenosine crystal-containing powder containing these crystals, the use of the same as a medical drug, and further, the use of the same as a cosmetic material or food product. The above-mentioned problem can be solved by providing crystals of 5'-glucosyl adenosine hydrochloride formed from one molecule of 5'-glucosyl adenosine and one molecule of hydrochloric acid.
C07H 19/167 - Radicaux purine avec un ribosyle comme radical saccharide
A23L 1/30 - contenant des additifs (A23L 1/308 a priorité);;
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 31/7076 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées contenant des purines, p. ex. adénosine, acide adénylique
A61P 1/02 - Préparations stomatologiques, p. ex. médicaments pour le traitement des caries, des aphtes, des périodontites
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
74.
ORAL WASHING COMPOSITION FOR PREVENTING AND/OR TREATING PERIODONTAL DISEASES
The purpose of the present invention is to provide an oral washing composition which can prevent and/or treat periodontal diseases safely and effectively. The purpose can be achieved by providing an oral washing composition which can prevent and/or treat periodontal diseases, said oral washing composition being characterized by containing at least one component selected from adenosine N1-oxide, 3'-glycosyl adenosine N1-oxide, 5'-glycosyl adenosine N1-oxide, 5'-adenosine diphosphate N1-oxide and 5'-adenosine triphosphate N1-oxide as an active ingredient and does not contain any sugar that can be utilized by periodontal disease bacteria.
The present invention addresses the problem of providing a novel mucosal adjuvant that is able to enhance antibody production, including that of antigen-specific secreted immunoglobulin A antibodies, by effectively enhancing mucosal immunity when an antigen is administered to the mucosal tissue, and that is stable and safe even when applied in vivo; and of providing a composition for enhancing antibody production in which the active ingredient is the adjuvant and an antigen. The problem is solved by providing a mucosal adjuvant in which the active ingredient is a tumor necrosis factor-α (TNF-α)-cholesterol pullulan complex, and a composition for enhancing antibody production in which the active ingredient is the adjuvant and an antigen.
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p. ex. par les adjuvants chimiques
Provided is a production method whereby it is possible to produce a powder containing crystalline trehalose dihydrate with starch as a starting material with high powder-to-starch yields. More specifically, provided is a production method for a powder containing crystalline α, α-trehalose dihydrate and having at least 98.0mass% of α, α-trehalose on an anhydrous basis, said method including: a step in which liquefied starch is subjected to the actions of a starch debranching enzyme, cyclomaltodextrin glucanotransferase, an α-glycosyl trehalose producing enzyme derived from a micro-organism belonging to the genus arthrobacter, and a trehalose releasing enzyme derived from a micro-organism belonging to the genus arthrobacter, and then to the action of glucoamylase, to obtain an α, α-trehalose-containing saccharide solution; a step in which α, α-trehalose dihydrate is crystallized from the saccharide solution; and a step in which the crystallized α, α-trehalose dihydrate is extracted by centrifugation, aged, and dried. The production method is characterized in that a natural or recombinant enzyme derived from a micro-organism belonging to the genus paenibacillus or a variant of such an enzyme is used as the cyclomaltodextrin glucanotransferase such that the content of α, α-trehalose in the saccharide solution is over 86.0mass% on an anhydrous basis, without having to undergo a column chromatography fractionation step.
C12P 19/16 - Préparation de composés contenant des radicaux saccharide préparés par action d'une alpha-1, 6 glucosidase, p. ex. amylose, amylopectine déramifiée
C12P 19/18 - Préparation de composés contenant des radicaux saccharide préparés par action d'une transférase glycosylique, p. ex. alpha-, bêta- ou gamma-cyclodextrines
C12P 19/20 - Préparation de composés contenant des radicaux saccharide préparés par action d'une exo-1, 4 alpha-glucosidase, p. ex. dextrose
The purpose of the present invention is to provide: a novel crystal of α-glucosyl hesperidin, of which the crystal structure is elucidated; a powder substantially comprising the crystal; and use of the powder as a material for a medicinal agent. The purpose can be achieved by providing: a crystal of α-glucosyl hesperidin, which has a crystallographic space group of P21, and of which the unit lattice has a lattice constant a of 13.983 Å, a lattice constant b of 7.620 Å and a lattice constant c of 20.065 Å, and which is a monoclinic crystal wherein α = γ = 90˚ and β = 93.475˚; a powder substantially comprising the crystal; and use of the powder as a material for a medicinal agent.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 3/02 - Nutriments, p. ex. vitamines, minéraux
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p. ex. arthrites, arthroses
The present invention has objects to provide a thermostable cellobiose 2-epimerase, its preparation and uses. The present invention attains the above objects by providing a thermostable cellobiose 2-epimerase, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a process for producing the enzyme, and a process for producing isomerized saccharides using the enzyme.
[Problem] To provide a method for producing an ascorbic acid 2-glucoside anhydrous crystal-containing powder with which it is possible to produce a powder that will not show significant solidification, even when the percentage of ascorbic acid 2-glucoside produced is less than 35 mass%. [Solution] A method for producing an ascorbic acid 2-glucoside anhydrous crystal-containing powder comprising a step in which a solution containing either liquefied starch or dextrin and L-ascorbic acid is exposed to CGTase and then to glucoamylase in order to obtain a solution wherein the percentage of ascorbic acid 2-glucoside produced is 27 mass% or greater; a step for purifying the resulting solution such that the ascorbic acid 2-glucoside content exceeds 86 mass%; a step for precipitating the ascorbic acid 2-glucoside anhydrous crystals by controlled cooling or semi-controlled cooling; and a step for recovering, aging, and drying the precipitated ascorbic acid 2-glucoside anhydrous crystals.
C07H 17/04 - Radicaux hétérocycliques contenant uniquement des atomes d'oxygène comme hétéro-atomes du cycle
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
The present invention addresses the problem of providing an external preparation for the skin having a sustainable antiwrinkle effect, which has an action of promoting the proliferation and differentiation of keratinocytes and an action of enhancing the collagen production in the skin at the same time, and which assists maintenance and improvement of the tissue structures and the physiological functions of the epidermis and the dermis, thereby providing an excellent skin improving effect. The problem is solved by providing an external preparation for the skin, which contains, as an effective ingredient, α-D-glucopyranosyl-(1→3')-adenosine and/or α-D-glucopyranosyl-(1→5')-adenosine.
A61K 31/047 - Composés hydroxylés, p. ex. alcoolsLeurs sels, p. ex. alcoolates ayant plusieurs groupes hydroxyle, p. ex. sorbitol
A61K 31/7076 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées contenant des purines, p. ex. adénosine, acide adénylique
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61P 17/16 - Émollients ou protecteurs, p. ex. contre les radiations
A61Q 19/00 - Préparations pour les soins de la peau
A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
C07H 19/167 - Radicaux purine avec un ribosyle comme radical saccharide
C12P 19/40 - Nucléosides avec un système cyclique condensé, contenant un cycle à six chaînons, comportant deux atomes d'azote dans le même cycle, p. ex. nucléosides puriques
81.
NEAR INTRARED-ABSORBING CYANINE PIGMENT AND USE THEREOF
The problem addressed by the invention is to provide a novel near infrared-absorbing cyanine pigment and a near infrared absorbent comprising same. The problem is solved by providing a benzo [c,d] indolium heptamethine cyanine pigment represented by formula (1) and a near infrared absorbent comprising same. (In formula (1), R1 and R2 each independently represent C1-5 straight or branched alkyl groups. R3 and R4 each independently represent hydrogen atoms or substituting groups. X- represents a counter anion.)
The present invention addresses the problem of providing a method for treating a photosensitive silver halide material that is used to produce a bleached phase hologram which has excellent light resistance and by which high diffraction efficiency can be achieved even after long term storage, and providing a bleached phase hologram which is obtained using this treatment method, which has excellent light resistance and by which high diffraction efficiency can be achieved. The problem can be solved by providing a method for treating a photosensitive silver halide material for a hologram in order to obtain a bleached phase hologram in which the difference between absorbance at a wavelength of 420 nm and absorbance at a wavelength of 470 nm is 2 or higher in transmission/absorption spectrometry. The treatment method includes a step of exposing the photosensitive silver halide material for a hologram, which has a silver halide emulsion layer that contains a photosensitive silver halide emulsion on a support body, to light, carrying out developing treatment and then bleaching treatment using ethylenediaminetetraacetic acid or a salt thereof as a bleaching treatment material, and then carrying out a stabilization treatment step using an aqueous solution of potassium iodide.
G03H 1/18 - Traitement particulier de supports d'enregistrement holographiques, p. ex. pour obtenir un hologramme à effet de "blaze", c.-à-d. présentant un profil destiné à favoriser un ordre particulier de diffraction
G03H 1/02 - Procédés ou appareils holographiques utilisant la lumière, les infrarouges ou les ultraviolets pour obtenir des hologrammes ou pour en obtenir une imageLeurs détails spécifiques Détails
The objective of the present invention is to provide a novel pyrrolopyridine compound and a use thereof, and provided are a pyrrolopyridine compound represented by general formula (1) and a use thereof. (In general formula (1), X represents a structure wherein one or more aromatic rings and/or heteroaromatic rings selected from among monocyclic or condensed polycyclic aromatic rings and monocyclic or condensed polycyclic heteroaromatic rings are bonded with each other; R1 represents a hydrogen atom or a substituent; R2 to R5 each independently represents a hydrogen atom or a substituent; the bonding position of each substituent may be any one of the ortho position, the meta position and the para position of each phenyl group to which the substituent is bonded; when substituents are bonded at two or more positions among the ortho position, the meta position and the para position of each phenyl group, these substituents may be the same as or different from each other, and substituents adjacent to each other may combine together and form a cyclic structure together with a carbon atom to which the substituents are bonded; and n represents 1 or 2.)
C07D 519/00 - Composés hétérocycliques contenant plusieurs systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un système carbocyclique commun non prévus dans les groupes ou
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
H01L 51/05 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés au redressement, à l'amplification, à la génération d'oscillations ou à la commutation et ayant au moins une barrière de potentiel ou une barrière de surface; Condensateurs ou résistances à l'état solide, ayant au moins une barrière de potentiel ou une barrière de surface
H01L 51/50 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED)
84.
HYDROUS CRYSTALS OF 2-O-α-D-GLUCOSYL-L-ASCORBIC ACID, POWDER CONTAINING HYDROUS CRYSTALS OF 2-O-α-D-GLUCOSYL-L-ASCORBIC ACID, METHOD FOR PRODUCING THE HYDROUS CRYSTALS, METHOD FOR PRODUCING THE POWDER, USE OF THE HYDROUS CRYSTALS, AND USE OF THE POWDER
The objective of the present invention is to provide novel 2-O-α-D-glucosyl-L-ascorbic acid crystals, a method for producing the novel 2-O-α-D-glucosyl-L-ascorbic acid crystals, and use of the novel 2-O-α-D-glucosyl-L-ascorbic acid crystals. The objective is achieved by providing hydrous crystals of 2-O-α-D-glucosyl-L-ascorbic acid, a powder containing hydrous crystals of 2-O-α-D-glucosyl-L-ascorbic acid, a method for producing the hydrous crystals of 2-O-α-D-glucosyl-L-ascorbic acid, a method for producing the powder containing hydrous crystals of 2-O-α-D-glucosyl-L-ascorbic acid, a use of the hydrous crystals of 2-O-α-D-glucosyl-L-ascorbic acid, and a use of the powder containing hydrous crystals of 2-O-α-D-glucosyl-L-ascorbic acid.
C07H 17/04 - Radicaux hétérocycliques contenant uniquement des atomes d'oxygène comme hétéro-atomes du cycle
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61P 17/16 - Émollients ou protecteurs, p. ex. contre les radiations
85.
AGENT FOR ENHANCING WHITENING EFFECT AND USE OF SAME
The purpose of the present invention is to provide a highly safe agent for enhancing the whitening effect of a whitening ingredient and a whitening agent, said whitening agent comprising a whitening ingredient together with the aforesaid agent for enhancing the whitening effect thereof and having an improved and enhanced whitening effect. Provided is an agent for enhancing whitening effect which comprises, as the active ingredient, one or more members selected from guanine and analogs thereof. Also provided is a whitening agent which comprises the aforesaid agent for enhancing whitening effect together with a whitening ingredient, in particular, one or more members selected from adenine and analogs thereof and/or equol and analogs thereof.
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
In order to provide a novel nitric oxide generation regulator for effectively regulating nitric oxide generation from vascular endothelial cells, macrophage cells including microglial cells, and the like that can be safely used in vivo, disclosed is a nitric oxide generation regulator that has the trinuclear pentamethine cyanine dye represented by the belowmentioned general formula (1) as the active ingredient. (In the general formula (1), R represents a potentially branched alkyl group having 2-4 carbon atoms, and X- represents an appropriate counteranion.)
A61K 31/4709 - Quinoléines non condensées contenant d'autres hétérocycles
A61P 1/18 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles pancréatiques, p. ex. enzymes pancréatiques
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 9/02 - Cardiotoniques non-spécifiques, p. ex. médicaments pour le traitement des syncopes, antihypotenseurs
A61P 9/04 - Agents inotropes, c.-à-d. stimulants de la contraction cardiaqueMédicaments pour le traitement de l'insuffisance cardiaque
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
A61P 37/06 - Immunosuppresseurs, p. ex. médicaments pour le traitement du rejet de greffe
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
C07D 215/12 - Composés hétérocycliques contenant les systèmes cycliques de la quinoléine ou de la quinoléine hydrogénée ne comportant pas de liaison entre l'atome d'azote du cycle et un chaînon non cyclique ou ne comportant que des atomes d'hydrogène ou de carbone liés directement à l'atome d'azote du cycle avec des radicaux hydrocarbonés substitués liés aux atomes de carbone du cycle
87.
THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES CONTAINING ADENOSINE N1-OXIDE AS ACTIVE INGREDIENT
Disclosed is an effective and safe therapeutic agent for inflammatory diseases such as sepsis, pneumonia, and inflammatory bowel diseases, which contains adenosine N1-oxide or a derivative thereof as an active ingredient.
C07H 19/067 - Radicaux pyrimidine avec un ribosyle comme radical saccharide
A61K 31/7076 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées contenant des purines, p. ex. adénosine, acide adénylique
A61P 1/04 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des ulcères, des gastrites ou des œsophagites par reflux, p. ex. antiacides, antisécrétoires, protecteurs de la muqueuse
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 1/18 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles pancréatiques, p. ex. enzymes pancréatiques
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
The purpose is to provide a pullulan-containing powder, which can be produced without resorting to a troublesome purification step using, for example, solvent precipitation and, when shaped into a film, shows a higher breaking strength than the existing products, a method for producing the pullulan-containing powder, and use thereof. For this, a pullulan-containing powder, which is produced by culturing a variant of a microorganism belonging to Aureobasidium pllulans in a medium containing glucose and maltose as a carbon source without resorting to a step for removing contaminating saccharides from the culture product thus obtained, said pullulan-containing powder being characterized by comprising a pullulan fraction that is insoluble in 75 vol.% aqueous methanol and a contaminating saccharide fraction that is soluble therein, the ratio (determined by the anthron-sulfuric acid method) of contaminating saccharides contained in the contaminating saccharide fraction being 3 mass% or less relative to the total saccharides contained in the whole powder, and containing mannitol, a method for producing the pullulan-containing powder, and use thereof are provided.
