The Florida International University Board of Trustees (USA)
Inventeur(s)
Rahman, Mohammad Ashiqur
Akkaya, Kemal
Asif, Muneeba
Abrégé
Systems and methods are provided for control and intrusion detection in unmanned aerial vehicles (UAVs). Pulse width modulation (PWM) signals can be used as both control indicators and a basis for intrusion detection. PWM signals can be monitored to detect irregularities that may signify potential intrusions, capitalizing on the predictable nature of PWM signal patterns under normal operating conditions, where deviations can indicate an attack. By analyzing these variations in real time, anomalies can be detected to prevent or inhibit further compromising of the UAV hardware. Also, PWM data can be fused with control inputs to enhance system responsiveness, creating a robust, adaptive intrusion detection system that maintains UAV hardware integrity and safeguards mission-critical functions even in adversarial environments.
B64U 101/15 - Véhicules aériens sans pilote spécialement adaptés à des utilisations ou à des applications spécifiques à la guerre conventionnelle ou électronique
2.
ARSINOTHRICIN AND METHODS OF TREATING INFECTIONS USING ARSINOTHRICIN
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Rosen, Barry Philip
Yoshinaga, Masafumi
Abrégé
Certain embodiments of the invention pertain to a method of treating an infection in a subject caused by an infectious agent other than Escherichia coli, the method comprising administering to the subject arsinothricin or a salt thereof. The infectious agent other than E. coli can be a bacterium, protozoan, helminth, archaebacterium, or a fungus. In preferred embodiments, the infectious agent is Mycobacterium tuberculosis, Mycobacterium bovis, or Enterobacter cloacae. The invention also pertains to a method of treating an infection in a subject caused by an infectious agent, comprising administering to the subject arsinothricin or a salt thereof in combination with an inhibitor of phosphinothricin N-acetyltransferase or arsinothricin N-acetyltransferase. In certain such embodiments, the infectious agent expresses phosphinothricin N-acetyltransferase or arsinothricin N-acetyltransferase. Further embodiments provide compositions comprising arsinothricin or a salt thereof and an inhibitor of phosphinothricin N-acetyltransferase or arsinothricin N-acetyltransferase.
A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
A61K 31/4468 - Pipéridines non condensées, p. ex. pipérocaïne ayant un atome d'azote lié directement en position 4, p. ex. clébopride, fentanyl
A61K 31/454 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pimozide, dompéridone
A61K 31/4985 - Pyrazines ou pipérazines condensées en ortho ou en péri avec des systèmes hétérocycliques
A61K 31/5415 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p. ex. sulthiame condensés en ortho ou en péri avec des systèmes carbocycliques, p. ex. phénothiazine, chlorpromazine, piroxicam
The Florida International University Board of Trustees (USA)
Inventeur(s)
Mekdad, Yassine
Uluagac, Selcuk
Acar, Abbas
Abrégé
Systems, methods, and frameworks for detecting malicious WebAssembly (Wasm) modules under source code obfuscation are provided. The system is configured to accurately identify malicious behavior in Wasm modules irrespective of the specific malicious functionality and in the presence of source code obfuscation techniques. The detection process leverages a Vision Transformer (ViT) model to classify a Wasm module as benign or malicious, enabling robust identification of threats across diverse attack patterns. The system operates with substantially low runtime overhead on computing resources, making it suitable for integration into real-time web application environments.
G06F 21/00 - Dispositions de sécurité pour protéger les calculateurs, leurs composants, les programmes ou les données contre une activité non autorisée
G06F 21/54 - Contrôle des utilisateurs, des programmes ou des dispositifs de préservation de l’intégrité des plates-formes, p. ex. des processeurs, des micrologiciels ou des systèmes d’exploitation au stade de l’exécution du programme, p. ex. intégrité de la pile, débordement de tampon ou prévention d'effacement involontaire de données par ajout de routines ou d’objets de sécurité aux programmes
G06F 21/56 - Détection ou gestion de programmes malveillants, p. ex. dispositions anti-virus
The Florida International University Board of Trustees (USA)
Inventeur(s)
Lin, Wei-Chiang
Abrégé
Machine-human interface (MHI) systems for control of powered external movement devices, such as prosthetics (e.g., prosthetic hands and/or arms), are provided, as well as methods of using the same. The efficient MHI systems leverage features of computer vision and pattern recognition to examine the subjects and/or objects within the field of view of a user of the system, and then uses artificial intelligence and/or machine learning to guess the user's intention. Once the user acknowledges the guessed intention, the MHI system can measure the location of the targeted subject/object using a measuring means (e.g., using Light Detection and Ranging (LIDAR) technology) and then coordinate the movement of the external movement device (e.g., prosthetic arm and/or hand).
A61F 4/00 - Procédés ou dispositifs permettant à des patients ou à des personnes handicapées de commander un appareil ou un dispositif ne faisant pas partie du corps
A61F 2/54 - Bras ou mains artificiels ou leurs parties
The Florida International University Board of Trustees (USA)
Inventeur(s)
Dey, Preyojon
Boymelgreen, Alicia Aron
Abrégé
Systems and methods are provided for comprehensive in vivo nanotoxicity testing, as well as fabrication methods of chips used for nanotoxicity testing. A three-dimensional (3D)-printed, automated microfluidic chip can be configured for in vivo nanotoxicity testing, and the chip can allow for multi-route (e.g., waterborne and/or foodborne) exposure of marine organisms to small materials (e.g., plastics such as microplastics and/or nanoplastics (NPLs), or metals), providing real-time, in situ monitoring of bioaccumulation and oxygen consumption.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Perez-Pons, Alexander
De La Cruz, Sebastian
Abrégé
Systems and methods for transforming program control flow data into space-filling curves for anomaly detection are provided. A system includes emulating a microcontroller (MCU) in a virtual environment, mapping program control flow data onto a Hilbert space-filling curve to preserve execution locality and applying a convolutional neural network (CNN) to identify anomalies in the resulting spatial representation. The approach improves embedded system security by enabling efficient evaluation of control flow behavior.
G06F 9/44 - Dispositions pour exécuter des programmes spécifiques
G06F 9/455 - ÉmulationInterprétationSimulation de logiciel, p. ex. virtualisation ou émulation des moteurs d’exécution d’applications ou de systèmes d’exploitation
G06F 11/3698 - Environnements pour l’analyse, le débogage ou le test de logiciel
7.
Systems and methods for connecting UHPC structural elements
The Florida International University Board of Trustees (USA)
Inventeur(s)
Mehrabi, Armin Barzegar
Odelola, Michael
Khedmatgozar Dolati, Seyed Saman
Abrégé
Systems and methods for connecting (and/or splicing) ultra-high-performance concrete (UHPC) precast elements are provided, as well as the finished connected UHPC elements after connection. The UHPC precast elements can be designed for applications in building construction and/or civil engineering. Overhang connection structures and spar connection structures are provided. In either case, holes can be created in one UHPC beam segment (e.g., by casting or drilling) to accommodate dowel bars from a corresponding UHPC segment.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Sarwat, Arif I.
Behnamfar, Milad
Abrégé
Methods and systems for dynamic wireless power transfer to charge an electric vehicle (EV) in motion are provided. The method can include: transmitting wireless power from a plurality of main transmitter coils; transmitting wireless power from a assisted coil disposed between each pair of adjacent main transmitter coils; receiving the wireless power at a receiver coil when the electric vehicle is charged in motion; providing a primary compensation network coupled to the main transmitter coils and the assisted coils; and compensating for reactive power at a secondary side by a secondary compensation network coupled to the receiver coil. Dimensions and positions of the assisted coils and parameters of the compensation network are configured to maintain a substantially constant mutual inductance profile between the transmitter coils and the receiver coil when the electric vehicle is charged in motion, thereby reducing power pulsation and providing a stable output voltage to the battery of the EV.
B60L 53/122 - Circuits ou procédés pour entraîner la bobine primaire, c.-à-d. en alimentant la bobine en énergie électrique
B60L 53/30 - Détails de construction des stations de charge
B60L 53/62 - Surveillance et commande des stations de charge en réponse à des paramètres de charge, p. ex. courant, tension ou charge électrique
B60L 53/67 - Commande de plusieurs stations de charge
H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
H02J 50/40 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant plusieurs dispositifs de transmission ou de réception
9.
SYSTEMS AND METHODS FOR BLOCKCHAIN-BASED SECURE MULTIPARTY COMPUTATION
The Florida International University Board of Trustees (USA)
The United States of America as represented by the Secretary of the Air Force (USA)
Inventeur(s)
Bautista Chia, Oscar G.
Hernandez Garcia, Richard
Akkaya, Kemal
Uluagac, Selcuk
Homsi, Soamar
Manshaei, Mohammad Hossein
Abrégé
Systems and methods for secure multiparty computation (MPC) over blockchain that packs messages into blockchain transactions are provided. MPC can be over Algorand blockchain that packs messages into Algorand transactions and utilizes its fast gossip protocol to transmit them efficiently among MPC parties (e.g., MPC nodes). The messages can be appended to a note field in the respective Algorand transactions.
G06Q 20/38 - Protocoles de paiementArchitectures, schémas ou protocoles de paiement leurs détails
G06Q 20/02 - Architectures, schémas ou protocoles de paiement impliquant un tiers neutre, p. ex. une autorité de certification, un notaire ou un tiers de confiance
The Florida International University Board of Trustees (USA)
Inventeur(s)
Gutierrez-Hernandez, Melany
Duarte, Sally P.
Bojja-Venkatakrishnan, Satheesh
Diaz, Jorge Riera
Volakis, John L.
Abrégé
Systems and methods for neurosensing are provided. A wireless neurosensing system (WiNS), which can be battery-less and/or multichannel, can include a sensor that receives an external electromagnetic (EM) signal (i.e., a carrier signal) through biological tissue communication. The sensor can be configured to be implanted into a subject (e.g., an organoid or a mammalian subject, such as a human subject) and can be referred to herein as the implant. The external EM signal can be received from an interrogator configured to remain outside the subject. The sensor can mix the carrier signal with an electrical signal of interest (SoI) and transmit it back to the external interrogator for posterior demodulation and/or processing. The systems and methods can be employed in many applications to measure the electrical signal in biological or non-biological settings.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Alwan, Elias Antoun
Uddin, Md Nazim
Abrégé
An extremely wideband reconfigurable antenna system is provided, including a plurality of planar inverted-F antennas, operating in a frequency range of 0.5 GHz to 4 GHz; a plurality of square patch antennas, operating in a frequency range of 4 GHz to 10 GHz; a plurality of circular patch antennas, operating in a frequency range of 10 GHz to 40 GHz; a plurality of multilayer stacked-up folded antennas, operating in a frequency range of 40 GHz to 110 GHz; a plurality of square patch antennas including a plurality of Jerusalem cross elements, operating in a frequency range of 110 GHz to 170 GHz; and a plurality of subarrays of horn-like tapered slot antennas, operating in a frequency range of 170 GHz to 300 GHz.
H01Q 9/44 - Antennes résonnantes avec une pluralité d'éléments linéaires divergents, p. ex. dipôle en V, antenne en XAntennes résonnantes avec une pluralité d'éléments ayant des parties sensiblement rectilignes, mutuellement inclinées
The Florida International University Board of Trustees (USA)
Inventeur(s)
Sarwat, Arif Islam
Stevenson, Alexander Joseph
Abrégé
Systems, architectures, devices, and methods for the resilient artificial intelligence-based data-driven dispatch of a battery energy storage system (BESS) are provided. A Mixed-Integer Linear Programming-based BESS dispatch scheduling algorithm utilizes location-specific weather data to forecast photovoltaic generation, load consumption, and grid outages using a plurality of machine learning models, in combination with market data to optimize energy dispatch decisions. A sustainable solution is provided for enabling improved load management during islanded conditions, providing advance operator alerts to enhance safety, and delivering economic benefits by minimizing unplanned outages, reducing associated financial losses, and offsetting high capital costs of BESS deployment through optimized utilization.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Lin, Wei-Chiang
Jiao, Shuliang
Zhou, Rui
Tsoukias, Nikolaos
Abrégé
Systems and methods for retinal imaging are provided. A heads-up display (HUD) can be integrated with advanced retinal imaging modalities, including optical coherence tomography (OCT) and fundoscopy (e.g., fluorescence fundoscopy). The HUD can serve as a crucial component of this approach, offering several key functionalities (e.g., a fixation target and/or a means for dark adaptation).
A61B 3/12 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
14.
Systems and methods for privacy-aware weapon anomaly detection via integrated object recognition and skeletal motion analysis
The Florida International University Board of Trustees (USA)
Inventeur(s)
Ding, Liwei
Amini, Mohammadhadi
Abrégé
Systems, methods, and frameworks are provided for privacy-aware weapon anomaly detection via integrated object recognition and skeletal motion analysis. This framework integrates real-time object detection and motion analysis to identify weapon anomalies in video surveillance while preserving privacy. The framework combines a fine-tuned object detection model, a head-segmentation module for anonymizing unarmed individuals, and a skeleton-based motion analysis module to detect threatening behaviors. By refining and fusing detection and motion analysis outputs, the framework enhances detection accuracy and reduces false positives, thereby providing a reliable solution for intelligent, privacy-preserving surveillance applications.
G06V 40/20 - Mouvements ou comportement, p. ex. reconnaissance des gestes
G06V 10/26 - Segmentation de formes dans le champ d’imageDécoupage ou fusion d’éléments d’image visant à établir la région de motif, p. ex. techniques de regroupementDétection d’occlusion
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
G06V 20/52 - Activités de surveillance ou de suivi, p. ex. pour la reconnaissance d’objets suspects
G06V 40/10 - Corps d’êtres humains ou d’animaux, p. ex. occupants de véhicules automobiles ou piétonsParties du corps, p. ex. mains
15.
Systems and methods for stabilizing power and voltage in dynamic wireless charging
The Florida International University Board of Trustees (USA)
Inventeur(s)
Sarwat, Arif I.
Behnamfar, Milad
Abrégé
Systems and methods are provided for stabilizing power and voltage in dynamic wireless charging (e.g., of electric vehicles). Systems and methods can use a composite control that combines a backstepping control approach with passivity-based control to stabilize output voltage during movement of the load (e.g., travel of the electric vehicle) and/or changing load conditions. As an example, a Lyapunov function-based control method can be used to regulate output voltage and power by controlling a boost converter at the secondary side. Systems and methods can ensure that the output voltage remains independent of load conditions, while also effectively maintaining smooth power delivery even as the load and mutual coupling fluctuate simultaneously, demonstrating rapid response to varying load conditions and mutual coupling.
H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries
B60L 53/122 - Circuits ou procédés pour entraîner la bobine primaire, c.-à-d. en alimentant la bobine en énergie électrique
B60L 53/60 - Surveillance et commande des stations de charge
H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
H02J 50/70 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la réduction des champs de fuite électriques, magnétiques ou électromagnétiques
H02J 50/40 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant plusieurs dispositifs de transmission ou de réception
H02M 3/156 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation
16.
SYNTHESIS OF DNA MOLECULES IN IN VITRO ENZYMATIC SYSTEMS
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Leng, Fenfei
Abrégé
A method, which synthesizes closed circular single-stranded and double-stranded DNA molecules using in vitro enzymatic systems, is described. Circular single-stranded DNA molecules and double-stranded DNA molecules (e.g., relaxed, or supercoiled) with various sizes can be synthesized. Unwanted DNA molecules, e.g., unligated oligomers, can be removed by exonucleases, such as T5 exonuclease, T7 exonuclease, lambda exonuclease, E. coli exonuclease I and/or III. A method of converting the single-stranded circular DNA molecules into double-stranded circular DNA molecules is also described. The single-stranded and double-stranded circular DNA molecules can be used in a variety of applications.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Agarwal, Arvind
Benedetti, Luiza
Orikasa, Kazue
Aguiar, Branon
Abrégé
Nanocomposites and fabrication methods thereof are provided. The nanocomposites can include two-dimensional (2D) material and one or more shape memory polymers (SMPs), thereby combining the unique properties of SMPs with the exceptional attributes of 2D materials. The nanocomposites exhibit enhanced mechanical, thermal, electrical, and radiation shielding properties. 2D materials can be integrated into three-dimensional (3D)-printed SMPs, allowing for development of smart and complex-shaped nanocomposites.
B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
B33Y 80/00 - Produits obtenus par fabrication additive
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
B82Y 40/00 - Fabrication ou traitement des nanostructures
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
C08K 3/30 - Composés contenant du soufre, du sélénium ou du tellure
The Florida International University Board of Trustees (USA)
Inventeur(s)
Lin, Wei-Chiang
Prasad, Anamika
Abrégé
Systems, devices, and methods for in vivo tissue diagnosis are provided. Optical spectroscopy can be utilized to characterize the morphological and/or compositional characteristics of in vivo tissue, and an indentation method can be used to measure the mechanical characteristics of the tissue. These intrinsic properties can then be used to detect disease and/or injury development in the in vivo tissue. A portable, handheld device can be used to perform the optical spectroscopy and/or the indentation method.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Sarwat, Arif I.
Behnamfar, Milad
Abrégé
Systems and methods for dynamic wireless power transfer (DWPT) are provided (e.g., DWPT of electric vehicles (EVs)). The inductor of the secondary compensation network can be integrated with the main inductive coil, which can introduce mutual couplings (e.g., three mutual couplings) in the system. The additional mutual coupling leads to a smooth power profile and an increase in power (e.g., power transferred during dynamic charging). The secondary compensation network inductor coil and the secondary main coil can be designed, configured, and/or arranged in a way that mutual coupling between them and the transmitter coils produces a uniform power profile.
H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
H02J 50/40 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant plusieurs dispositifs de transmission ou de réception
The Florida International University Board of Trustees (USA)
Inventeur(s)
Rosen, Barry P.
Yoshinaga-Sakurai, Kunie
Nadar, Venkadesh Sarkarai
Abrégé
The subject invention provides organoarsenicals or salts thereof, compositions comprising an organoarsenical or a salt thereof, and methods of using the organoarsenicals or salts thereof, or compositions for inhibiting glutaminase and for treating cancers. Specifically, the subject invention provides methods of inhibiting glutaminase (e.g., KGA) catalytic activity in a cell, methods of treating cancer or a tumor via, for example, the inhibition of glutaminase activity, and methods of disrupting and/or inhibiting growth and proliferation of cancerous or tumorous cells.
C12N 9/99 - Inactivation des enzymes par traitement chimique
C12Q 1/34 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase
21.
Polymer nanocomposite flexible films for electromagnetic interference shielding
The Florida International University Board of Trustees (USA)
Inventeur(s)
Agarwal, Arvind
Pulugurtha, Markondeyaraj
Lou, Lihua
Al-Duhni, Ghaleb Saleh Ghaleb
Abrégé
Materials are provided that can be used for electromagnetic interference (EMI) shielding, and methods of fabricating the same and methods of using the same are also provided. Polymer-based fiber thin films can have superior electrical conductivity and excellent EMI shielding efficiency while being ultra-flexible and ultra-lightweight. The fiber thin films can be dual polymer thin films and can incorporate quantum dots (QDs) (e.g., magnetic quantum dots) and/or two-dimensional (2D) conductive nanomaterials within a dual polymer matrix comprising a conductive polymer and a nonconductive polymer. The resultant composite thin film can have low density, high porosity, and high electrical conductivity.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Pulugurtha, Markondeyaraj
Venkatakrishnan, Satheesh Bojja
Volakis, John
Rathnayaka, Sajith
Abrégé
Systems and methods are provided for electronic manufacturing, including use of a rigid tile-in-polymer film panel. Rigid tiles can be molded with a thin polymer composite to form the rigid tile-in-polymer film panel. The rigid panel can be made of silicon, glass, ceramic ribbon, or traditional glass fiber-reinforced laminates depending on the target product segment.
H01L 23/538 - Dispositions pour conduire le courant électrique à l'intérieur du dispositif pendant son fonctionnement, d'un composant à un autre la structure d'interconnexion entre une pluralité de puces semi-conductrices se trouvant au-dessus ou à l'intérieur de substrats isolants
H01L 23/00 - Détails de dispositifs à semi-conducteurs ou d'autres dispositifs à l'état solide
H01L 23/31 - Encapsulations, p. ex. couches d’encapsulation, revêtements caractérisées par leur disposition
H01L 25/18 - Ensembles consistant en une pluralité de dispositifs à semi-conducteurs ou d'autres dispositifs à l'état solide les dispositifs étant de types prévus dans plusieurs différents groupes principaux de la même sous-classe , , , , ou
The Florida International University Board of Trustees (USA)
Inventeur(s)
Madanayake, Habarakada Liyanachchi Prabath Arjuna
Abrégé
Systems and methods are provided for reducing the computational complexity and all-to-all (A2A) communication within virtual sub-arrays (VSAs) while enabling distributed parallel edge processing. This can help solve the beamforming problem described by The United States Defense Advanced Research Projects Agency (DARPA) state of the art array processor (SOAP) unclassified program. The use of all-digital transmit/receive antenna apertures for adaptive beamforming algorithms necessitate inversion of large matrices. The matrix inversions become intractably difficult for emerging all-digital apertures. This complexity problem associated with large all-digital aperture arrays can be solved with a two-level approach.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Nair, Madhavan
Raymond, Andrea
Vashist, Arti
Abrégé
A method of treatment or prevention of HIV and other viral infection comprising the administration of a biopolymer-based hydrogel nanoparticles and/or microparticles. In preferred embodiments, the particles comprise chitosan, hydroxyethyl cellulose (HEC), and linseed oil polyol. These biopolymer-based hydrogel nanoparticles and/or microparticles are antiviral agents that can be employed alone or in combination with other drugs for treatment of the viral infection. Further, the pre-treatment with the particles is highly effective at inhibiting viruses. Therefore, this antiviral biopolymer-based hydrogel nanoparticles and/or microparticles may also be employed as a prophylactic.
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Tieu, Kim
Nefzi, Adel
Black, Stephen
Abrégé
The subject invention provides compounds as Drp1 inhibitors, compositions comprising a Drp1 inhibitor, and methods for inhibiting Drp1 protein using the Drp1 inhibitors. Further provided are methods for treating and/or preventing a disease or condition associated with mitochondrial dysfunction, oxidative stress, inflammation and/or autophagy. Advantageously, the compounds and compositions of the subject invention can also be used to treat a variety of other conditions including, for example, autoimmune disorders, disorders of the nervous system, and cardiovascular disorders.
C07D 417/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
26.
Inline monitoring system for process defects during manufacturing
The Florida International University Board of Trustees (USA)
Inventeur(s)
Pulugurtha, Markondeyaraj
Venkatakrishnan, Satheesh Bojja
Volakis, John
Awasthi, Peeyush
Giordano, Anthony
Abrégé
Systems and methods are provided for inline process monitoring (e.g., remote inline process monitoring) for scalable and precision high-yield manufacturing. Antenna probes, such as millimeter (mm) wave (mmWave) antenna (mWA) probes, can be introduced into fabrication equipment to reveal the nature of hidden conductor and/or dielectric defects, as well as via-pad and/or device pad-trace misalignments, going beyond automated optical inspection (AOI) or contact probing.
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Ramaswamy, Sharan D.
Perez-Nevarez, Manuel
Mirza, Asad
Lin, Yih-Mei
Ibarra, Amanda
Arman, Pranavi
Abrégé
This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help prevent or reduce scar tissue growth in cardiovascular system and restore heart function. According to certain embodiments, a fluid-induced, pathological shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for preventing or reducing scar tissue growth in cardiovascular system. Therefore, compositions comprising the exosomes derived from stem cells and methods of preventing and/or treating scar tissue growth in cardiovascular system by administering the exosomes isolated from stem cells are also provided.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61K 38/18 - Facteurs de croissanceRégulateurs de croissance
A61K 38/40 - Transferrines, p. ex. lactoferrines, ovotransferrines
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
The Florida International University Board of Trustees (USA)
Inventeur(s)
Rosen, Barry Philip
Yoshinaga, Masafumi
Abrégé
Enterobacter cloacae. The invention also pertains to a method of treating an infection in a subject caused by an infectious agent, comprising administering to the subject arsinothricin or a salt thereof in combination with an inhibitor of phosphinothricin N-acetyltransferase or arsinothricin N-acetyltransferase. In certain such embodiments, the infectious agent expresses phosphinothricin N-acetyltransferase or arsinothricin N-acetyltransferase. Further embodiments provide compositions comprising arsinothricin or a salt thereof and an inhibitor of phosphinothricin N-acetyltransferase or arsinothricin N-acetyltransferase.
A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
A61K 31/4468 - Pipéridines non condensées, p. ex. pipérocaïne ayant un atome d'azote lié directement en position 4, p. ex. clébopride, fentanyl
A61K 31/454 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pimozide, dompéridone
A61K 31/4985 - Pyrazines ou pipérazines condensées en ortho ou en péri avec des systèmes hétérocycliques
A61K 31/5415 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un soufre comme hétéro-atomes d'un cycle, p. ex. sulthiame condensés en ortho ou en péri avec des systèmes carbocycliques, p. ex. phénothiazine, chlorpromazine, piroxicam
The Florida International University Board of Trustees (USA)
Inventeur(s)
Larkins, Grover L.
Abrégé
Systems and methods for X-ray imaging using intensity modulated X-rays are provided. A narrow band filtering system can be used to improve the signal-to-noise ratio (SNR) and contrast of X-ray imaging. Systems and methods can also include a modification to an X-ray tube to permit grid-based intensity modulation and/or a masking scheme for sub-pixels to increase the dynamic range of the resulting pixels. Four different types of X-ray imaging systems can be used and can include intensity modulated X-rays through a narrow band filtering system to improve the SNR and contrast of X-ray imaging.
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A61B 6/40 - Agencements pour générer des radiations spécialement adaptés au diagnostic par radiations
30.
Systems and methods for detecting vehicle position during dynamic wireless charging
The Florida International University Board of Trustees (USA)
Inventeur(s)
Sarwat, Arif I.
Behnamfar, Milad
Tariq, Mohd
Abrégé
Systems and methods are provided for detecting vehicle position during electric vehicle charging using machine learning, as well as a control scheme for activating charging coils when the vehicle crosses them. The machine learning can have as inputs the primary current, the vehicle ground clearances, and the speed of the vehicle. As different vehicles with different ground clearances are traveling across the transmitter coils for charging, ground clearance can be defined as a variable for machine learning. Vehicles can move at different speeds, so the speed of the vehicle can be considered in the prediction of the vehicle position.
B60L 53/126 - Procédés pour associer un véhicule et une station de charge, p. ex. en établissant une relation directe entre un transmetteur d'énergie sans fil et un récepteur d'énergie sans fil
G06N 20/20 - Techniques d’ensemble en apprentissage automatique
31.
POLYOLS AND POLYOL-BASED HYDROGELS WITH ANTI-CANCER ACTIVITY
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Vashist, Arti
Raymond, Andrea D.
Chapagain, Prem
Nair, Madhavan P.
Runowicz, Carolyn D.
Abrégé
The present invention provides compositions and methods for selectively treating a cancer or tumor utilizing an effective amount of a vegetable oil-derived polyol or hydrogel particles comprising a vegetable oil-derived polyol. In some embodiments, the cancer is a gynecologic cancer, specifically an ovarian cancer. In other aspects, the present invention provides a method of targeting and imaging various tumors and/or tumor associated macrophages (TAMs).
The Florida International University Board of Trustees (USA)
Inventeur(s)
Hamrani, Abderrachid
Godavarty, Anuradha
Abrégé
Systems and methods for classification and/or analysis of skin color(s) are provided. The technology integrates artificial intelligence (AI) with dermatology to enhance skin color classification. The unique matching technique aligns skin images with the Fitzpatrick skin type palette through Euclidean distance matching, achieving higher precision in skin color classification compared to conventional methods.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Hamza, Muhammad
Georgakopoulos, Stavros
Zekios, Constantinos L.
Exadaktylos, Christos
Abrégé
Dual-polarized ultrawideband antennas and antenna arrays are provided. Fully inverted-L elements (FILEs) can be used as the radiating element in a unit cell antenna, which can be repeated to form an array. The dual-polarized FILE unit cell can include two L-bent elements, which tightly couple to a common shorted via as well as to each other. The same shorted via can be utilized to suppress the well-known common mode resonance.
H01Q 21/24 - Combinaisons d'unités d'antennes polarisées dans des directions différentes pour émettre ou recevoir des ondes polarisées circulairement ou elliptiquement ou des ondes polarisées linéairement dans n'importe quelle direction
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Dimitroff, Charles J.
Mohammed, Norhan B. B.
Abrégé
The present invention provides methods and composition for diagnosis, prognosis, prevention and/or treatment of cancers such as melanomas. The subject invention provides biomarkers (e.g., galectin-3 (Gal-3)) and methods for assessing the severity of a cancer/tumor and for monitoring the progressing of a cancer/tumor. The compositions according to the subject invention regulate and alter melanoma signaling, growth, and survival. The subject invention also provides molecular mechanisms governing melanoma metastasis to identify candidate diagnostic or prognostic markers and develop novel therapeutic opportunities. Further, the subject invention identifies the tumor-suppressive function of Gal-3 in melanoma cells, emphasizing the negative crosstalk between Gal-3 and NFAT1 and its role in dictating melanoma metastasis.
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61P 35/04 - Agents anticancéreux spécifiques pour le traitement des métastases
C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
35.
ARRAYS WITH THREE-DIMENSIONAL CONFORMAL RADIATING ELEMENTS
The Florida International University Board of Trustees (USA)
Inventeur(s)
Kaddour, Abdul-Sattar
Georgakopoulos, Stavros
Abrégé
Antenna arrays with three-dimensional (3D) conformal radiating elements are provided, as well as methods of manufacturing and methods of using the same. An array can include a ground plane and a plurality of unit cells disposed thereon. Each unit cell can include a 3D conformal radiating element. The 3D conformal radiating elements can be, for example, patches (e.g., circular 3D patches), dipoles, or loops, and each radiating element is conformal on a hemispherical shape.
H01Q 5/48 - Combinaisons de plusieurs antennes de type dipôle
H01Q 3/46 - Lentilles actives ou réseaux réfléchissants
H01Q 15/04 - Dispositifs de réfraction ou diffraction, p. ex. lentille, prisme comportant un canal ou des canaux guide d'onde limités par des surfaces conductrices sensiblement perpendiculaires au vecteur champ électrique de l'onde, p. ex. lentille guide d'ondes à plaques parallèles
H01Q 21/06 - Réseaux d'unités d'antennes, de même polarisation, excitées individuellement et espacées entre elles
H01Q 21/20 - Réseaux d'unités d'antennes, de même polarisation, excitées individuellement et espacées entre elles les unités étant espacées le long d'un trajet curviligne ou adjacent à celui-ci
H01Q 21/26 - Antennes tourniquet ou similaires comportant des dispositions de trois éléments ou plus allongés disposés radialement et symétriquement dans un plan horizontal par rapport à un centre commun
36.
FEDERATED DEEP REINFORCEMENT LEARNING-ASSISTED UAV TRAJECTORY PLANNING AGAINST HOSTILE DEFENSE SYSTEM
The Florida International University Board of Trustees (USA)
Inventeur(s)
Rahman, Mohammad Ashiqur
Khalil, Alvi Ataur
Abrégé
Systems, frameworks, and methods for reinforcement learning (RL)-based real-time path planning for unmanned aerial vehicles (UAVs) are provided. The learning capabilities of federated learning (FL) can be integrated with an improved deep RL framework, including using a significant reply memory buffer (SRMB) to accelerate the intelligent behavior. The framework can train a UAV to intelligently dodge static and dynamic defense systems and achieve assigned goals (e.g., in a hostile area). The FL can enable collaborative learning through a swarm of UAV agents.
G05D 1/46 - Commande de la position ou du cap dans les trois dimensions
G05D 101/15 - Détails des architectures logicielles ou matérielles utilisées pour la commande de la position utilisant des techniques d’intelligence artificielle [IA] utilisant l’apprentissage automatique, p. ex. les réseaux neuronaux
G05D 105/35 - Applications spécifiques des véhicules commandés pour le combat
37.
Dual-band antenna array with stacked rotman lens feed for beamforming
The Florida International University Board of Trustees (USA)
Inventeur(s)
Volakis, John L.
Hossain, Muhammad Mubasshir
Venkatakrishnan, Satheesh Bojja
Koulouridis, Stavros
Abrégé
Systems and methods are provided for simultaneous beamforming at two close frequency bands. Rotman-lens-based beamforming modules with low size, weight, and power (SWaP) can be used. A stacked array Rotman lens module can use a low cost feeding type of layer-to-layer energy transitions, and the stacked module can be capable of simultaneous beamforming at two close frequency bands.
H01Q 25/00 - Antennes ou systèmes d'antennes fournissant au moins deux diagrammes de rayonnement
H01Q 1/28 - Adaptation pour l'utilisation dans ou sur les avions, les missiles, les satellites ou les ballons
H01Q 1/48 - Moyens de mise à la terreÉcrans de terreContrepoids
H01Q 5/20 - Dispositions pour faire fonctionner simultanément des antennes sur plusieurs gammes d'ondes, p. ex. dispositions bibandes ou multibandes caractérisées par les gammes d'ondes exploitées
H01Q 5/30 - Dispositions permettant un fonctionnement sur différentes gammes d’ondes
38.
RECONFIGURABLE PACKAGE INTEGRATED ELECTRO MAGNETIC INTERFERENCE SHIELDING
The Florida International University Board of Trustees (USA)
Inventeur(s)
Al-Duhni, Ghaleb Saleh Ghaleb
Khasgiwala, Mudit Sunilkumar
Pulugurtha, Markondeyaraj
Volakis, John Leonidas
Ghosh, Kunal
Patel, Meghna Maheshkumar
Bojja Venkatakrishnan, Satheesh
Patil, Sachin Jayant
Abrégé
A tunable shielding system may include a substrate with a dielectric layer disposed on a surface of the substrate. The system may include a tunable metal patch including a metal plate attached to the substrate and encompassed in a magnetic layer, the tunable metal patch configured to be geometrically shifted. The system may include a direct current coil adjacent to the metal plate, and a current source. The system may include one or more processors and a computer readable medium including instructions that cause the system to perform operations to determine that an electromagnetic interference signal is incident on the system, the electromagnetic interference signal characterized by a frequency. The system may also determine a current amount associated with the frequency. The system may provide the current amount to the direct current coil such that a magnetic field is generated such that the tunable metal patch geometrically shifts.
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Al-Duhni, Ghaleb Saleh Ghaleb
Khasgiwala, Mudit Sunilkumar
Pulugurtha, Markondeyaraj
Volakis, John Leonidas
Ghosh, Kunal
Patel, Meghna Maheshkumar
Bojja Venkatakrishnan, Satheesh
Patil, Sachin Jayant
Abrégé
A tunable shielding system may include a substrate with a dielectric layer disposed on a surface of the substrate. The system may include a tunable metal patch including a metal plate attached to the substrate and encompassed in a magnetic layer, the tunable metal patch configured to be geometrically shifted. The system may include a direct current coil adjacent to the metal plate. and a current source. The system may include one or more processors and a computer readable medium including instructions that cause the system to perform operations to determine that an electromagnetic interference signal is incident on the system, the electromagnetic interference signal characterized by a frequency. The system may also determine a current amount associated with the frequency. The system may provide the current amount to the direct current coil such that a magnetic field is generated such that the tunable metal patch geometrically shifts.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Banerjee, Reshmi
Pulugurtha, Markondeyaraj
Khasgiwala, Mudit Sunilkumar
Patel, Meghna Maheshkumar
Ghosh, Kunal
Kengeri, Subramani
Patil, Sachin Jayant
Khosravi, Arvin
Abrégé
A capacitor may include a substrate may include a cavity. The capacitor may include a plurality of particles disposed within the cavity. The capacitor may include a first metal layer, deposited on the substrate, within the cavity, and on the plurality of particles. The capacitor may include a dielectric layer, deposited on the first metal layer. The capacitor may include a second metal layer, deposited on the dielectric layer. The capacitor may include a third metal layer, deposited on the second metal layer such that the cavity is substantially filled.
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Banerjee, Reshmi
Pulugurtha, Markondeyaraj
Khasgiwala, Mudit Sunilkumar
Patel, Meghna Maheshkumar
Ghosh, Kunal
Kengeri, Subramani
Patil, Sachin Jayant
Khosravi, Arvin
Abrégé
A capacitor may include a substrate may include a cavity. The capacitor may include a plurality of particles disposed within the cavity. The capacitor may include a first metal layer, deposited on the substrate, within the cavity, and on the plurality of particles. The capacitor may include a dielectric layer, deposited on the first metal layer. The capacitor may include a second metal layer, deposited on the dielectric layer. The capacitor may include a third metal layer, deposited on the second metal layer such that the cavity is substantially filled.
H01L 23/13 - Supports, p. ex. substrats isolants non amovibles caractérisés par leur forme
H01L 23/498 - Connexions électriques sur des substrats isolants
H01L 23/522 - Dispositions pour conduire le courant électrique à l'intérieur du dispositif pendant son fonctionnement, d'un composant à un autre comprenant des interconnexions externes formées d'une structure multicouche de couches conductrices et isolantes inséparables du corps semi-conducteur sur lequel elles ont été déposées
H01L 23/532 - Dispositions pour conduire le courant électrique à l'intérieur du dispositif pendant son fonctionnement, d'un composant à un autre comprenant des interconnexions externes formées d'une structure multicouche de couches conductrices et isolantes inséparables du corps semi-conducteur sur lequel elles ont été déposées caractérisées par les matériaux
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Al-Duhni, Ghaleb Saleh Ghaleb
Khasgiwala, Mudit Sunilkumar
Pulugurtha, Markondeyaraj
Venkatakrishnan, Satheesh Bojja
Volakis, John Leonidas
Kengeri, Subramani
Ghosh, Kunal
Patel, Meghna Maheshkumar
Patil, Sachin Jayant
Khosravi, Arvin
Abrégé
A shielding structure for a semiconductor device may include a first segment formed from a first set of layers including a first metal and a second metal. The structure may include a second segment formed from a second set of layers. The second set of layers may include the first metal and the second metal, the second segment orthogonal to the first segment, where the second segment is configured to be inserted into a trench in a substrate of the semiconductor device.
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Al-Duhni, Ghaleb Saleh Ghaleb
Khasgiwala, Mudit Sunilkumar
Pulugurtha, Markondeyaraj
Pial, Mohammad Mohtasim Hamid
Kengeri, Subramani
Ghosh, Kunal
Patel, Meghna Maheshkumar
Patil, Sachin Jayant
Khosravi, Arvin
Abrégé
A scalable high-impedance component (SHIC) may include a flexible polyimide core may include one or more vias. The SHIC may include a magnetic film formed on one or more sides of the flexible polyimide core. The SHIC may include a polymer layer formed on the magnetic film, the polymer layer isolating the magnetic film and the flexible polyimide core. The SHIC may include a metal layer formed on the polymer layer and within the vias, such that the metal layer forms windings that extend through the one or more vias. The SHIC may include a magnetic paste disposed on the metal layer such that the SHIC shields a desired frequency of electromagnetic interference.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Al-Duhni, Ghaleb Saleh Ghaleb
Khasgiwala, Mudit Sunilkumar
Pulugurtha, Markondeyaraj
Pial, Mohammad Mohtasim Hamid
Kengeri, Subramani
Ghosh, Kunal
Patel, Meghna Maheshkumar
Patil, Sachin Jayant
Khosravi, Arvin
Abrégé
A scalable high-impedance component (SHIC) may include a flexible polyimide core may include one or more vias. The SHIC may include a magnetic film formed on one or more sides of the flexible polyimide core. The SHIC may include a polymer layer formed on the magnetic film, the polymer layer isolating the magnetic film and the flexible polyimide core. The SHIC may include a metal layer formed on the polymer layer and within the vias, such that the metal layer forms windings that extend through the one or more vias. The SHIC may include a magnetic paste disposed on the metal layer such that the SHIC shields a desired frequency of electromagnetic interference.
H01F 41/02 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateursAppareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants
The Florida International University Board of Trustees (USA)
Inventeur(s)
Al-Duhni, Ghaleb Saleh Ghaleb
Khasgiwala, Mudit Sunilkumar
Pulugurtha, Markondeyaraj
Bojja Venkatakrishnan, Satheesh
Volakis, John Leonidas
Kengeri, Subramani
Ghosh, Kunal
Patel, Meghna Maheshkumar
Patil, Sachin Jayant
Khosravi, Arvin
Abrégé
A shielding structure for a semiconductor device may include a first segment formed from a first set of layers including a first metal and a second metal. The structure may include a second segment formed from a second set of layers. The second set of layers may include the first metal and the second metal, the second segment orthogonal to the first segment, where the second segment is configured to be inserted into a trench in a substrate of the semiconductor device.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Pial, Mohammad Mohtasim Hamid
Khasgiwala, Mudit Sunilkumar
Pulugurtha, Markondeyaraj
Kengeri, Subramani
Ghosh, Kunal
Patel, Meghna Maheshkumar
Patil, Sachin Jayant
Khosravi, Arvin
Abrégé
An inductor may include a flexible polyimide flexible core may including one or more cavities. The inductor may include a magnetic film, formed on two sides of the flexible polyimide flexible core and on a respective sidewall of each of the one or more cavities. The inductor may include a dielectric layer formed on the magnetic film. The inductor may also include a metal layer formed on the dielectric layer and within the cavities, such that vias are formed on one or more sides of the inductor and extend through the one or more cavities.
H01F 27/32 - Isolation des bobines, des enroulements, ou de leurs éléments
H01F 41/04 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateursAppareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants pour la fabrication de bobines
47.
Connection of precast concrete panels and walls using near surface mounted bars
The Florida International University Board of Trustees (USA)
Inventeur(s)
Mehrabi, Armin Barzegar
Vivas, Isabella Zapata
Khedmatgozar Dolati, Seyed Saman
Abrégé
Systems and methods for connection between precast concrete elements are provided. Near-surface mounting bars (NSMBs) can be used to connect panel elements (e.g., decks and/or slabs), concrete walls, retaining walls, and/or abutments. A straight or butt connection can be used for panel and wall elements, and a staggered or lap connection can be used for panel elements. The connection systems offer new ways for connecting precast concrete walls and deck panels.
E04B 1/04 - Structures constituées principalement d'éléments porteurs en forme de blocs ou de dalles les éléments étant en béton, p. ex. en béton armé, ou en un autre matériau pierreux
E04B 1/38 - Assemblages pour les constructions du bâtiment en général
E04C 5/16 - Pièces auxiliaires pour armatures, p. ex. pièces de séparation, étriers
48.
Systems and methods for performing temporal analysis
The Florida International University Board of Trustees (USA)
Inventeur(s)
Ocal, Mustafa
Finlayson, Mark
Abrégé
Systems and methods are provided for enabling users to work with TimeML annotations and perform advanced temporal analysis, offering a comprehensive suite of features. Systems and methods of embodiments allow users to parse TimeML annotations, construct TimeML graphs, and execute the timeline extraction (TLEX) algorithm to effect complete timeline extraction. An algorithm can be incorporated for increasing connectivity in temporal graphs, which identifies graph disconnectivity and recommends links based on temporal reasoning, thereby enhancing the coherence of the graph representation. Also, a built-in validation algorithm can be included, ensuring compliance with TimeML annotation guidelines.
The United States of America,as represented by the Secretary,Department of Health and Human Services (USA)
The Florida International University Board of Trustees (USA)
Inventeur(s)
Marugan, Juan J.
Southall, Noel T.
Ferrer, Marc
Henderson, Mark J.
Wilson, Kenneth J.
Agoulnik, Alexander I.
Myhr, Courtney B.
Esteban-Lopez, Maria
Barnaeva, Elena
Hu, Xin
Ye, Wenjuan
Agoulnik, Irina
Abrégé
Disclosed is a compound of formula (I), in which R1, R2, R3, R4, R5, X1, X2, X3, X4, and X5 are described herein. The small molecule compounds of formula (I) activate the functional activity of relaxin family peptide receptor 2 (RXFP2), thereby providing therapeutic treatments for a variety of disorders, such as a bone disorder, hypogonadism, cryptorchidism, polycystic ovary syndrome, cancer, infertility, or an ocular wound.
Disclosed is a compound of formula (I), in which R1, R2, R3, R4, R5, X1, X2, X3, X4, and X5 are described herein. The small molecule compounds of formula (I) activate the functional activity of relaxin family peptide receptor 2 (RXFP2), thereby providing therapeutic treatments for a variety of disorders, such as a bone disorder, hypogonadism, cryptorchidism, polycystic ovary syndrome, cancer, infertility, or an ocular wound.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Raymond, Andrea D.
Nair, Madhavan P.
Vashist, Arti
Andre, Mickensone
Abrégé
The subject invention provides compositions and methods for isolating exosomes from, for example, biological fluid samples, cell cultures and/or cultured medium. Provided are Absolute Precipitation of Exosomes (APEX) reagents and precipitation techniques to isolate exosomes from various EV subsets, cells, dead cells, and/or cell debris. Advantageously, APEX is a rapid, effortless, inexpensive, high-recovery method to extract exosomes. This method is also faster and purer at isolating exosomes from other precipitation techniques.
C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
The Florida International University Board of Trustees (USA)
Inventeur(s)
Lin, Wei-Chiang
Jiao, Shuliang
Zhou, Rui
Tsoukias, Nikolaos
Abrégé
Systems and methods for retinal imaging are provided. A heads-up display (HUD) can be integrated with advanced retinal imaging modalities, including optical coherence tomography (OCT) and fundoscopy (e.g., fluorescence fundoscopy). The HUD can serve as a crucial component of this approach, offering several key functionalities (e.g., a fixation target and/or a means for dark adaptation).
A61B 3/12 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
52.
BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Leng, Fenfei
Alfonso, Eddy
Deng, Zifang
Abrégé
The subject invention provides fluorophore-quencher nucleic acid molecules comprising relaxed or supercoiled DNA molecules, and their use in rapid and efficient high-throughput screening (HTS) assays to screen and identify compounds that inhibit DNA gyrases. These compounds can be used as antibiotics for treating bacterial infections, especially, multidrug resistant bacterial infections.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 31/185 - AcidesLeurs anhydrides, halogénures ou sels, p. ex. acides du soufre, acides imidiques, hydrazoniques ou hydroximiques
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
A61K 31/196 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino le groupe amino étant lié directement à un cycle, p. ex. acide anthranilique, acide méfénamique, diclofénac, chlorambucil
A61K 31/24 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques ayant un noyau aromatique lié au groupe carboxyle ayant un groupe amino ou nitro
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
A61K 31/366 - Lactones ayant des cycles à six chaînons, p. ex. delta-lactones
A61K 31/381 - Composés hétérocycliques ayant le soufre comme hétéro-atome d'un cycle ayant des cycles à cinq chaînons
A61K 31/443 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'oxygène comme hétéro-atome du cycle
A61K 31/473 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. acridines, phénantridines
A61K 31/475 - QuinoléinesIsoquinoléines ayant un cycle indole, p. ex. yohimbine, réserpine, strychnine, vinblastine
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
A61K 31/498 - Pyrazines ou pipérazines condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. quinoxaline, phénazine
A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine
A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
A61K 31/7076 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées contenant des purines, p. ex. adénosine, acide adénylique
The Florida International University Board of Trustees (USA)
Universita' Degli Studi "G. d'Annunzio" Chieti-Pescara (Italie)
Inventeur(s)
Kabir, Abuzar
Furton, Kenneth G.
Locatelli, Marcello
Tartaglia, Angela
Abrégé
Devices and methods for use in extraction procedures of analytes (organic and inorganic, including heavy metals) from matrices (e.g., complex matrices) in various fields (e.g., biological, clinical, chemical, environmental, toxicological, and forensic) are provided. The device can comprise a support structure acting as a rigid and stable support for extraction materials that can be inserted thereinto. The device can comprise a plurality of windows in the support structure through which the extraction materials can be exposed. The device can include two portions that can join together (e.g., using an interlocking system).
The Florida International University Board of Trustees (USA)
Inventeur(s)
Tieu, Kim
Nefzi, Adel
Black, Stephen
Abrégé
The subject invention provides compounds as Drp1 inhibitors, compositions comprising a Drp1 inhibitor, and methods for inhibiting Drp1 protein using the Drp1 inhibitors. Further provided are methods for treating and/or preventing a disease or condition associated with mitochondrial dysfunction, oxidative stress, inflammation and/or autophagy. Advantageously, the compounds and compositions of the subject invention can also be used to treat a variety of other conditions including, for example, autoimmune disorders, disorders of the nervous system, and cardiovascular disorders.
C07D 417/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
55.
Method for encrypting NFT's using dynamic key exchange on the blockchain
The Florida International University Board of Trustees (USA)
Inventeur(s)
Subramanian, Hemang
Abrégé
Systems and methods for providing a decentralized marketplace for patient-generated health data are provided. The systems and methods can store medical records on an interplanetary file system (IPFS) and blockchain, with the ability to encrypt and decrypt data on the IPFS and blockchain. This can securely associate and/or dissociate users from their “owned” property, securely transfer the ownership of records, securely share the records to other users, facilitate payment for nonfungible token (NFT) records, and/or facilitate transfers to aggregators of health records.
G06Q 20/00 - Architectures, schémas ou protocoles de paiement
G06F 21/62 - Protection de l’accès à des données via une plate-forme, p. ex. par clés ou règles de contrôle de l’accès
G06Q 20/38 - Protocoles de paiementArchitectures, schémas ou protocoles de paiement leurs détails
G06Q 20/40 - Autorisation, p. ex. identification du payeur ou du bénéficiaire, vérification des références du client ou du magasinExamen et approbation des payeurs, p. ex. contrôle des lignes de crédit ou des listes négatives
The Florida International University Board of Trustees (USA)
Savannah River Nuclear Solutions, LLC (USA)
Inventeur(s)
Mcdaniel, Dwayne E.
Abbasi Baharanchi, Ahmadreza
Poirier, Michael
Tashakori, Shervin
Abrégé
Systems and methods for determining the yield stress of a non-Newtonian fluid in real time are provided. A pressure loss and/or liquid rise technique, an ultrasonic technique, and/or a penetrometer technique can be used to determine the yield stress of a non-Newtonian fluid. The ultrasonic technique can include a longitudinal wave approach and/or a shear wave approach. The methods and systems are non-invasive and only require slight modifications to the piping containing the non-Newtonian fluid in order to measure the yield stress.
G01N 11/08 - Recherche des propriétés d'écoulement des matériaux, p. ex. la viscosité, la plasticitéAnalyse des matériaux en déterminant les propriétés d'écoulement en mesurant l'écoulement du matériau à travers un passage étroit, p. ex. un tube, une ouverture en mesurant la pression nécessaire à la production d'un écoulement connu
G01N 11/00 - Recherche des propriétés d'écoulement des matériaux, p. ex. la viscosité, la plasticitéAnalyse des matériaux en déterminant les propriétés d'écoulement
57.
Biotherapy for viral infections using biopolymer based micro/nanogels
The Florida International University Board of Trustees (USA)
Inventeur(s)
Nair, Madhavan
Raymond, Andrea
Vashist, Arti
Abrégé
A method of treatment or prevention of HIV and other viral infection comprising the administration of a biopolymer-based hydrogel nanoparticles and/or microparticles. In preferred embodiments, the particles comprise chitosan, hydroxyethyl cellulose (HEC), and linseed oil polyol. These biopolymer-based hydrogel nanoparticles and/or microparticles are antiviral agents that can be employed alone or in combination with other drugs for treatment of the viral infection. Further, the pre-treatment with the particles is highly effective at inhibiting viruses. Therefore, this antiviral biopolymer-based hydrogel nanoparticles and/or microparticles may also be employed as a prophylactic.
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Ramaswamy, Sharan D.
Nevarez, Manuel Perez
Mirza, Asad
Lin, Yih-Mei
Ibarra, Amanda
Arman, Pranavi
Abrégé
This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help prevent or reduce scar tissue growth in cardiovascular system and restore heart function. According to certain embodiments, a fluid-induced, pathological shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for preventing or reducing scar tissue growth in cardiovascular system. Therefore, compositions comprising the exosomes derived from stem cells and methods of preventing and/or treating scar tissue growth in cardiovascular system by administering the exosomes isolated from stem cells are also provided.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61K 38/18 - Facteurs de croissanceRégulateurs de croissance
A61K 38/40 - Transferrines, p. ex. lactoferrines, ovotransferrines
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
Florida State University Research Foundation, Inc. (USA)
The Florida International University Board Of Trustees (USA)
Inventeur(s)
Stefanovic, Branko
Nefzi, Adel
Abrégé
This discloses that compounds of Formula 1 have antifibrotic properties. In particular, this discloses a pharmaceutical composition including one or more compounds of Formula 1 and methods of using compounds of Formula 1 in fibrosis treatment and inhibiting type 1 collagen synthesis.
C07D 403/04 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
60.
Devices and methods for nanofiber-based membrane fabrication
The Florida International University Board of Trustees (USA)
Inventeur(s)
Agarwal, Arvind
Cruz, Omar Blandon
Lou, Lihua
Abrégé
Devices and methods for nanofiber-based membrane fabrication are provided. Portable (e.g., handheld) electrostatic spinning or electrospinning devices can be used for nanofiber-based membrane fabrication (e.g., wound care films or membranes, such as cannabidiol (CBD)-loaded films or membranes) and can be wearable and/or ultralow power. The device can include a needleless spinneret having solution supplied thereto and all powered by a low voltage battery.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Agarwal, Arvind
Sukumaran, Abhijith Kunneparambil
Aguiar, Brandon A.
Zhang, Cheng
Abrégé
Erosion test rigs are provided for propelling dust and/or particles at high velocity and providing variable temperature ranges, as well as methods of using and fabricating the same. The erosion test rig can propel dust and/or particles at a velocity of up to 400 meters per second (m/s) and generate wide temperature ranges (e.g., from −196° C. to 200° C.) to simulate the harsh erosive conditions of planetary environments (e.g., Mars and Luna).
The Florida International University Board of Trustees (USA)
Inventeur(s)
Madanayake, Habarakada Liyanachchi Prabath Arjuna
Abrégé
Systems and methods for wireless simultaneous transmit and receive (STAR) using multi-input multi-output (MIMO) radiofrequency (RF) front-ends are provided. A MIMO front-end can be based on the use of a symmetrical pair of arrays, in which one is used for communication while the other is used inside an RF-shielded chamber to act as a reference for subtracting self-interference between transmitters and receivers. In addition to the two arrays, the system can include two identical passive microwave multi-beam beamforming networks. The beamformer networks can be, for example, Butler Matrix based, true-time delay microwave networks, or Rotman lens based.
H04B 7/04 - Systèmes de diversitéSystèmes à plusieurs antennes, c.-à-d. émission ou réception utilisant plusieurs antennes utilisant plusieurs antennes indépendantes espacées
The Florida International University Board of Trustees (USA)
Inventeur(s)
Leng, Fenfei
Dias, Matthew
Abrégé
The subject invention provides a novel fluorescence-based, T5 exonuclease-amplified DNA cleavage assay for gyrase poisoning inhibitor discovery. According to the assay, multiple gyrase molecules can simultaneously bind to a plasmid DNA molecule to form multiple gyrase-DNA cleavage complexes on the same plasmid. These gyrase-DNA cleavage complexes, greatly stabilized by a gyrase poisoning inhibitor, and can be trapped by a detergent such as sarkosyl. Digestion of gyrase by proteinase K results in the production of small DNA fragments, which can be digested by T5 exonuclease. This fluorescence-based DNA cleavage HTS assay is also suitable for screening large compound libraries to identify inhibitors against DNA topoisomerases, including human DNA topoisomerase IIα.
C12Q 1/37 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase faisant intervenir une peptidase ou une protéinase
C12Q 1/44 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase une estérase
C12Q 1/533 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une isomérase
C12Q 1/6832 - Amélioration de la réaction d’hybridation
64.
Additive-polymer composite materials and methods of fabricating the same
The Florida International University Board of Trustees (USA)
Inventeur(s)
Radu, Daniela Rodica
Lai, Cheng-Yu
Venedicto, Melissa
Syed, Faizan
Thomas, Dakota Aaron
Oyon, Samuel
Abrégé
Additive-polymer precursor materials for filaments (e.g., for three-dimensional (3D) printing) are provided, as well as methods of fabricating and using the same. One or more two-dimensional (2D) additive materials (e.g., nano materials, such as nanosheets) can be mixed with a polymer base to give an additive-polymer precursor composite material. The additive material can be dissolved in a first solvent to give an additive solution, and the polymer can be dissolved in a second solvent to give a polymer base. The additive solution can be mixed with the polymer base to give a mixed solution. Solvent casting can then be performed on the mixed solution to evaporate the solvent(s) and give the additive-polymer precursor composite material, which can have a layered structure.
C08K 3/11 - Composés contenant des métaux des groupes 4 à 10 ou des groupes 14 à 16 du tableau périodique
B29C 48/14 - Moulage par extrusion, c.-à-d. en exprimant la matière à mouler dans une matrice ou une filière qui lui donne la forme désiréeAppareils à cet effet caractérisés par les conditions particulières d’extrusion, p. ex. dans une atmosphère modifiée ou par l’utilisation de vibrations
C08K 3/30 - Composés contenant du soufre, du sélénium ou du tellure
65.
System and method for real-time detection of unrestricted file upload vulnerabilities in Node.js applications
The Florida International University Board of Trustees (USA)
Inventeur(s)
Oz, Harun
Aris, Ahmet
Acar, Abbas
Kharraz, Amin
Uluagac, Selcuk
Abrégé
Systems and methods for detecting unrestricted file upload (UFU) vulnerabilities in Node.js (e.g., Node.js web applications) are provided. A lightweight framework can be used, drawing on a comprehensive evaluation of unique UFU-type attack types from multiple sources. By tailoring these attack instances to the Node.js ecosystem, systems and methods of embodiments of the subject invention offer more thorough coverage of potential attack vectors than existing technologies and tools.
G06F 21/57 - Certification ou préservation de plates-formes informatiques fiables, p. ex. démarrages ou arrêts sécurisés, suivis de version, contrôles de logiciel système, mises à jour sécurisées ou évaluation de vulnérabilité
The Florida International University Board of Trustees (USA)
Inventeur(s)
Pulugurtha, Markondeyaraj
Agarwal, Arvind
Zhang, Cheng
Banerjee, Reshmi
John, Denny
Abrégé
Cold-sprayed aluminum capacitors on lead frame metal foils are provided for applications in 3D power package integration. This additive manufacturing process allows pre-patterned low-temperature processing of aluminum electrodes on metal lead frames, insulated metal substrates or even heat-spreaders and cold-plates. Cold-sprayed capacitors can eliminate several process integration and reliability issues that are associated with traditional discrete surface-assembled capacitors.
H01G 13/00 - Appareils spécialement adaptés à la fabrication de condensateursProcédés spécialement adaptés à la fabrication de condensateurs non prévus dans les groupes
The Florida International University Board of Trustees (USA)
Inventeur(s)
Hamza, Muhammad
Georgakopoulos, Stavros
Zekios, Constantinos L.
Abrégé
Ultra-wideband (UWB) arrays that are fully planar are provided. Fully-planar inverted-L element (FILE) arrays that are tightly coupled arrays (TCAs) can realize UWB tightly coupled apertures in the W and higher millimeter wave (mmWave) bands. The unit cell architecture of the FILE array, (which can have any desired size, can be comprised of an inverted-L shaped antenna and a capacitively coupled via-fence.
H01Q 21/06 - Réseaux d'unités d'antennes, de même polarisation, excitées individuellement et espacées entre elles
H01Q 1/40 - Éléments rayonnants recouverts avec, ou enrobés d'une matière protectrice
H01Q 5/25 - Systèmes à ultralarge bande, p. ex. systèmes à résonnance multipleSystèmes à impulsions
H01Q 9/42 - Antennes résonnantes avec alimentation à l'extrémité d'un élément actif allongé, p. ex. unipôle avec éléments repliés, les parties repliées étant espacées l'une de l'autre d'une petite fraction de la longueur d'onde émise
The Florida International University Board of Trustees (USA)
Inventeur(s)
Vashist, Arti
Raymond, Andrea D.
Chapagain, Prem
Nair, Madhavan P.
Runowicz, Carolyn D.
Abrégé
The present invention provides compositions and methods for selectively treating a cancer or tumor utilizing an effective amount of a vegetable oil-derived polyol or hydrogel particles comprising a vegetable oil-derived polyol. In some embodiments, the cancer is a gynecologic cancer, specifically an ovarian cancer. In other aspects, the present invention provides a method of targeting and imaging various tumors and/or tumor associated macrophages (TAMs).
The Florida International University Board of Trustees (USA)
Inventeur(s)
Pala, Nezih
Hasan, Muhammad Mahmudul
Abrégé
Systems and methods are provided for assisting individuals with physical and/or cognitive ailments, such as dementia, Alzheimer's disease, and/or visual impairment. The quality of life, safety, and/or autonomy of such individuals can be enhanced by utilizing a combination of sensors, actuators, augmented reality (AR) technology, and machine learning (ML) algorithms. The sensors and actuators can include (but are not limited to) cameras, global positioning system (GPS) sensors, accelerometers, motion sensors, AR visual systems, headphones, microphones, haptic feedback systems, and/or connectivity capabilities (wired and/or wireless) to provide information about the surrounding environment and events. By leveraging advanced sensor technology, AR, and real-time data processing, a comprehensive support system can be provided that addresses the unique challenges faced by these individuals on a daily basis.
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
G06V 20/20 - ScènesÉléments spécifiques à la scène dans les scènes de réalité augmentée
G16H 20/00 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients
70.
SYSTEMS AND METHODS FOR PATIENT-SPECIFIC EPILEPTIC SEIZURE PREDICTION
A patient specific epileptic seizure(ES) prediction model using only electroencephalography (EEG) data with residual neural networks (ResNets) and transfer learning (TL) techniques (i.e., SPERTL) is provided. One exemplary provided model was trained on EEG data from 23 patients with a seizure prediction horizon (SPH) of 5 minutes and used the validation data to plot precision-recall curves to aid in selecting preferred thresholds. Testing on unseen data shows the provided model outperforms related art methods by achieving the highest average sensitivity of 88.1%, specificity of 92.3%, and accuracy of 92.3%. Results also demonstrate the proposed model is less susceptible to false positives while maintaining a high positive prediction rate.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Kabir, Abuzar
Furton, Kenneth G.
Anthemidis, Aristidis
Manousi, Natalia
Abrégé
The present invention provides materials, devices and methods for detecting, determining, monitoring and/or extracting one or more metals such as cadmium, lead, copper, chromium, cobalt, nickel, zinc, manganese, mercury, vanadium, arsenic, and silver in fluid samples. The present invention also provides formulations and methods for synthesizing a metal-extracting materials comprising a pyridylethylthiopropyl functionalized sol-gel silica-based sorbent.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01D 15/02 - Procédés de séparation comportant le traitement de liquides par des adsorbants ou des absorbants solidesAppareillages pour ces procédés par des adsorbants en mouvement
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
72.
MULTI-SPECIES REFERENCE LADDER AND MULTI-PLEX PCR KIT AND USES THEREOF
The Florida International University Board of Trustees (USA)
Inventeur(s)
Mills, Deetta Kay
Ostenson, Vallarie
Kaufman, Lindsey
Burns, Christina Anne
Abrégé
The subject invention provides multi-species reference ladders, multiplex PCR kits, and methods for multi-species identification using the multi-species reference ladders and multiplex PCR kits. Advantageously, the multi-species reference ladder and multiplex kit allows for a stream-lined analysis process and rapid species identification in a single test.
C12Q 1/6888 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes
The Florida International University Board of Trustees (USA)
Inventeur(s)
Wang, Chunlei
Jafarizadeh, Borzooye
Chowdhury, Azmal
Khakpour, Iman
Pala, Nezih
Abrégé
The subject invention is concerned with systems and methods advantageously applying finite element analysis to establish design rules for a highly sensitive piezo-resistive pressure sensor with an output that is high enough to be detectable by simple and inexpensive circuits and therefore ensure wearability. Four frequently reported micro-feature shapes in micro-patterned piezo-resistive sensors are provided, where the micro-dome and micro-pyramid yield the highest sensitivity. Investigations of different conductivity values of micro-patterned elastomers show that coating the elastomer with a conductive material (e.g., a metallic coating) leads to higher current response when compared to composited conductive elastomers. Advantageous geometric parameters and spatial configurations of micro-pyramid design of piezo-resistive sensors are provided. Results show that an enhanced sensitivity and higher current output can be achieved by a lower spatial density configuration of three micro-features per millimeter length, a smaller feature size of around 100 μm, and a 60-50 degrees pyramid angle.
G01L 1/18 - Mesure des forces ou des contraintes, en général en utilisant des propriétés des matériaux piézo-résistants, c.-à-d. des matériaux dont la résistance ohmique varie suivant les modifications de la grandeur ou de la direction de la force appliquée au matériau
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
74.
Hybrid carbon nanofibers products and methods of fabricating the same
The Florida International University Board of Trustees (USA)
Inventeur(s)
Agarwal, Arvind
Nisar, Ambreen
Lou, Lihua
Boesl, Benjamin Peter
Abrégé
Hybrid carbon nanofiber (Cnf) products (e.g., mats, yarns, webs, etc.) and methods of fabricating the same are provided. The hybrid Cnf products are flexible and lightweight and have high thermal conductivity. An electrospinning process can be used to fabricate the hybrid Cnf products and can include preparation of an electrospinning solution, electrospinning, and carbonization (e.g., under a vacuum condition).
D01F 9/22 - Filaments de carboneAppareils spécialement adaptés à leur fabrication par décomposition de filaments organiques à partir de produits de polyaddition, de polycondensation ou de polymérisation à partir de composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone à partir de polyacrylonitriles
C08J 3/20 - Formation de mélanges de polymères avec des additifs, p. ex. coloration
C08J 3/21 - Formation de mélanges de polymères avec des additifs, p. ex. coloration en présence d'une phase liquide le polymère étant prémélangé avec une phase liquide
C09K 5/08 - Substances qui ne subissent pas de changement d'état physique lors de leur utilisation
C09K 5/14 - Substances solides, p. ex. pulvérulentes ou granuleuses
D01D 5/00 - Formation des filaments, fils ou similaires
D01F 1/10 - Autres agents modifiant les propriétés de ces filaments
D01F 9/24 - Filaments de carboneAppareils spécialement adaptés à leur fabrication par décomposition de filaments organiques à partir de produits de polyaddition, de polycondensation ou de polymérisation à partir de composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
D04H 3/03 - Non-tissés formés uniquement ou principalement de fils ou de matériaux filamenteux similaires de bonne longueur caractérisés par la méthode de formation des voiles ou couches, p. ex. par la réorientation des fils ou filaments au hasard
The Florida International University Board Of Trustees (USA)
Inventeur(s)
Adjouadi, Malek
Eslami, Mohammad
Tabarestani, Solale
Abrégé
Systems and methods are provided for color-coded visualization to aid in diagnosis and prognosis of Alzheimer's disease (AD). The color-coded visualization mechanism can be driven by an integrated machine learning (ML) model, which can take as its inputs neuroimaging (e.g., magnetic resonance imaging (MRI), positron emission tomography (PET)) data, neuropsychological test scores, the cerebrospinal fluid (CSF) biomarker, and/or risk factors. With these inputs, the ML model can generate a color-coded visualization of the disease state.
G06V 10/80 - Fusion, c.-à-d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 6/50 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des parties du corps spécifiquesAppareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des applications cliniques spécifiques
G06V 10/77 - Traitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
The Florida International University Board of Trustees (USA)
Inventeur(s)
Pulugurtha, Markondeyaraj
Agarwal, Arvind
Zhang, Cheng
Banerjee, Reshmi
John, Denny
Abrégé
Cold-sprayed aluminum capacitors on lead frame metal foils are provided for applications in 3D power package integration. This additive manufacturing process allows pre-patterned low-temperature processing of aluminum electrodes on metal lead frames, insulated metal substrates or even heat-spreaders and cold-plates. Cold-sprayed capacitors can eliminate several process integration and reliability issues that are associated with traditional discrete surface-assembled capacitors.
H01G 13/00 - Appareils spécialement adaptés à la fabrication de condensateursProcédés spécialement adaptés à la fabrication de condensateurs non prévus dans les groupes
The Florida International University Board of Trustees (USA)
Inventeur(s)
Hamza, Muhammad
Georgakopoulos, Stavros
Zekios, Constantinos L.
Exadaktylos, Christos
Abrégé
Dual-polarized ultrawideband antennas and antenna arrays are provided. Fully inverted-L elements (FILEs) can be used as the radiating element in a unit cell antenna, which can be repeated to form an array. The dual-polarized FILE unit cell can include two L-bent elements, which tightly couple to a common shorted via as well as to each other. The same shorted via can be utilized to suppress the well-known common mode resonance.
H01Q 1/48 - Moyens de mise à la terreÉcrans de terreContrepoids
H01Q 5/25 - Systèmes à ultralarge bande, p. ex. systèmes à résonnance multipleSystèmes à impulsions
H01Q 21/24 - Combinaisons d'unités d'antennes polarisées dans des directions différentes pour émettre ou recevoir des ondes polarisées circulairement ou elliptiquement ou des ondes polarisées linéairement dans n'importe quelle direction
78.
SYSTEMS AND METHODS FOR PERFORMING PERIPHERAL VASCULAR IMAGING
The Florida International University Board of Trustees (USA)
Inventeur(s)
Godavarty, Anuradha
Hutcheson, Joshua Daniel
Leizaola, Daniela
Leiva, Kevin
Dargam, Valentina
Abrégé
Systems, devices, and methods for performing peripheral vascular imaging are provided. A continuous wave, non-contact, near-infrared optical scanner (NIROS) can utilize at least one near-infrared (NIR) light. The diffuse reflected NIR signal(s) can be obtained from the surface of the tissue of the mammal being imaged. The signal(s) can be optically filtered and can be detected by an NIR-sensitive image sensor. A graphical user interface (GUI) can be used to automate the acquisition of the spatio-temporal diffuse reflected maps from the NIROS device.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Raymond, Andrea D.
Nair, Madhavan P.
Vashist, Arti
Andre, Mickensone
Abrégé
The subject invention provides compositions and methods for isolating exosomes from, for example, biological fluid samples, cell cultures and/or cultured medium. Provided are Absolute Precipitation of Exosomes (APEX) reagents and precipitation techniques to isolate exosomes from various EV subsets, cells, dead cells, and/or cell debris. Advantageously, APEX is a rapid, effortless, inexpensive, high-recovery method to extract exosomes. This method is also faster and purer at isolating exosomes from other precipitation techniques.
C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
80.
NANOPARTICLES AND USES THEREOF FOR TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS
A61K 31/122 - Cétones ayant l'atome d'oxygène lié directement à un cycle, p. ex. quinones, vitamine K1, anthraline
A61K 31/403 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des carbocycles, p. ex. carbazole
A61K 31/427 - Thiazoles non condensés et contenant d'autres hétérocycles
A61K 31/435 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle
A61K 31/439 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle le cycle formant une partie d'un système cyclique ponté, p. ex. quinuclidine
A61K 31/4418 - Pyridines non condenséesLeurs dérivés hydrogénés ayant un carbocycle lié directement à l'hétérocycle, p. ex. cyproheptadine
A61K 31/4433 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'oxygène comme hétéro-atome du cycle
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
A61K 31/4709 - Quinoléines non condensées contenant d'autres hétérocycles
A61K 31/4741 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. dérivés du tubocurarane, noscapine, bicuculline
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
A61K 31/497 - Pyrazines non condensées contenant d'autres hétérocycles
A61K 31/4985 - Pyrazines ou pipérazines condensées en ortho ou en péri avec des systèmes hétérocycliques
A61K 31/499 - Pyrazines ou pipérazines condensées en spiro
A61K 31/5025 - PyridazinesPyridazines hydrogénées condensées en ortho ou en péri avec des systèmes hétérocycliques
A61K 31/505 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine
A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
A61K 31/522 - Purines, p. ex. adénine ayant des groupes oxo liés directement à l'hétérocycle, p. ex. hypoxanthine, guanine, acyclovir
A61K 31/536 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un oxygène comme hétéro-atomes d'un cycle, p. ex. 1,2-oxazines condensées en ortho ou en péri avec des systèmes carbocycliques
A61K 31/5365 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un oxygène comme hétéro-atomes d'un cycle, p. ex. 1,2-oxazines condensées en ortho ou en péri avec des systèmes hétérocycliques
A61K 31/537 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec au moins un azote et au moins un oxygène comme hétéro-atomes d'un cycle, p. ex. 1,2-oxazines condensées en spiro ou formant une partie de systèmes cycliques pontés
A61K 31/551 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant deux atomes d'azote comme hétéro-atomes d'un cycle, p. ex. clozapine, dilazèpe
A61K 31/573 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne à deux atomes de carbone, p. ex. prégnane ou progestérone substitués en position 21, p. ex. cortisone, dexaméthasone, prednisone ou aldostérone
A61K 31/616 - Acide salicyliqueSes dérivés ayant le groupe hydroxyle en position 2 estérifié, p. ex. acide salicylsulfurique par des acides carboxyliques, p. ex. acide acétylsalicylique
A61K 31/635 - Composés contenant des groupes para-N-benzènesulfonyl-N-, p. ex. sulfanilamide, p-nitrobenzènesulfonohydrazide contenant un hétérocycle, p. ex. sulfadiazine
A61K 31/675 - Composés du phosphore ayant l'azote comme hétéro-atome d'un cycle, p. ex. phosphate de pyridoxal
A61K 31/7072 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées ayant des groupes oxo liés directement au cycle pyrimidine, p. ex. cytidine, acide cytidylique ayant deux groupes oxo liés directement au cycle pyrimidine, p. ex. uridine, acide uridylique, thymidine, zidovudine
A61K 38/16 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
A61K 38/18 - Facteurs de croissanceRégulateurs de croissance
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61P 31/18 - Antiviraux pour le traitement des virus ARN du HIV
81.
SYSTEMS AND METHODS FOR EVALUATING HISTORICAL REAL ESTATE PRICE TRENDS
The Florida International University Board of Trustees (USA)
Inventeur(s)
Rishe, Naphtali David
Adjouadi, Malek
Abrégé
Systems and methods for evaluating historical trends in real estate prices are provided. Systems and methods provide an understanding of historical price trends and assist in a property evaluation or appraisal, as well as allowing for an analysis of comparables in estimating a reasonable offer for a property on the market. Given a timespan of interest, a locale, and a category of properties of interest, an objective historical trend in values can be computed by first evaluating the ratios between the realized prices of transactions and objective governmental assessment of the properties at some fixed point of time. Then, for each period the ratios of all transactions in that period can be averaged, followed by comparing said averages between different time periods.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Mohammed, Osama
Soliman, Ahmed
Rafin, S M Sajjad Hossain
Abrégé
Systems and methods for the control and operation of a grid-connected converter with an energy storage system are provided. The system can include a small microgrid comprising an AC grid that is feeding a DC load through a converter. The converter is connected to the AC grid through an R-L filter. The classical linear controllers have limitations due to their slow transient performance and low robustness against parameter variations and load disturbances. In certain embodiments, the transient and steady state responses of the provided artificial intelligence based Robust Artificial Neural Network Tracking Control (RANNTC) of three-phase grid-connected power converters has been shown to be more enhanced in terms of overshoot (24% lower), settling time (85% reduced), and total harmonic distortion (THD) (55% lower).
H02M 7/217 - Transformation d'une puissance d'entrée en courant alternatif en une puissance de sortie en courant continu sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
The Florida International University Board of Trustees (USA)
Inventeur(s)
Wang, Chunlei
Jafarizadeh, Borzooye
Chowdhury, Azmal
Khakpour, Iman
Pala, Nezih
Abrégé
The subject invention is concerned with systems and methods advantageously applying finite element analysis to establish design rules for a highly sensitive piezo-resistive pressure sensor with an output that is high enough to be detectable by simple and inexpensive circuits and therefore ensure wearability. Four frequently reported micro-feature shapes in micro-patterned piezo-resistive sensors are provided, where the micro-dome and micro-pyramid yield the highest sensitivity. Investigations of different conductivity values of micro-patterned elastomers show that coating the elastomer with a conductive material (e.g., a metallic coating) leads to higher current response when compared to composited conductive elastomers. Advantageous geometric parameters and spatial configurations of micro-pyramid design of piezo-resistive sensors are provided. Results show that an enhanced sensitivity and higher current output can be achieved by a lower spatial density configuration of three micro-features per millimeter length, a smaller feature size of around 100 μm, and a 60-50 degrees pyramid angle.
G01L 1/18 - Mesure des forces ou des contraintes, en général en utilisant des propriétés des matériaux piézo-résistants, c.-à-d. des matériaux dont la résistance ohmique varie suivant les modifications de la grandeur ou de la direction de la force appliquée au matériau
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Tieu, Kim
Nefzi, Adel
Black, Stephen
Abrégé
The subject invention provides compounds as Drp1 inhibitors, compositions comprising a Drp1 inhibitor, and methods for inhibiting Drp1 protein using the Drp1 inhibitors. Further provided are methods for treating and/or preventing a disease or condition associated with mitochondrial dysfunction, oxidative stress, inflammation and/or autophagy. Advantageously, the compounds and compositions of the subject invention can also be used to treat a variety of other conditions including, for example, autoimmune disorders, disorders of the nervous system, and cardiovascular disorders.
C07D 417/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
85.
Systems and methods for wireless simultaneous transmit and receive operation
The Florida International University Board of Trustees (USA)
Inventeur(s)
Madanayake, Habarakada Liyanachchi Prabath Arjuna
Abrégé
Systems and methods for wireless simultaneous transmit and receive (STAR) using multi-input multi-output (MIMO) radiofrequency (RF) front-ends are provided. A MIMO front-end can be based on the use of a symmetrical pair of arrays, in which one is used for communication while the other is used inside an RF-shielded chamber to act as a reference for subtracting self-interference between transmitters and receivers. In addition to the two arrays, the symmetry of the system can include two identical passive microwave multi-beam beamforming networks. The beamformer networks can be, for example, Butler Matrix based, true-time delay microwave networks, or Rotman lens based.
H04B 7/04 - Systèmes de diversitéSystèmes à plusieurs antennes, c.-à-d. émission ou réception utilisant plusieurs antennes utilisant plusieurs antennes indépendantes espacées
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Agarwal, Arvind
John, Denny
Zhang, Cheng
Abrégé
Provided is a method of repairing structures on the Lunar surface using Lunar regolith containing metallic coatings. An ultra-portable and low-pressure cold spray system is utilized to consolidate coatings. This system can be easily transported to space, reducing the payload. Lunar regolith is added to the metal powder before cold spray deposition. Lunar regolith increases the tampering effect during cold spray deposition, thereby causing severe plastic deformation of the metal powders and providing a coating with high quality and minimum porosity. The presence of Lunar regolith increases the hardness of the coating and improves wear properties. Coatings on a large area can be made rapidly without much surface preparation. These coatings can be rapidly applied to various Lunar structures to repair, reinforce, and restore (RRR) functionality and performance in the Lunar environment.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Cercado, Carlos Riera
Pulugurtha, Markondeyaraj
Gomez, Juan Camilo
Jaiswal, Veeru
Abrégé
Stacked magnetic cores that can achieve high density with a small footprint are provided. A stacked magnetic core can include a plurality of magnetic films with an adhesive film between each magnetic film and the adjacent magnetic film(s). That is, the magnetic films and adhesive films can be disposed in an alternating fashion. Each adhesive film can be a dielectric/insulating film such that each magnetic film is electrically insulated from every other magnetic film.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Godavarty, Anuradha
Leiva, Kevin
Abrégé
Systems and methods for imaging breath-hold (BH)-induced oxygenation changes in a patient are provided. A non-invasive, non-contact device can be used to image BH-induced oxygenation changes in one or more parts (e.g., foot) of a patient. The patient can hold his or her breath for a set amount of time while imaging is performed using the device, and the imaging can be performed before and/or after the time while the patient is holding his or her breath as well (e.g., during a recovery period). This enables tissue oxygenation based flow correlation independent of melanin concentration (e.g., skin color) of the patient and/or the curvature of the tissue (of the patient) being imaged.
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Lialios, Dimitrios
Zekios, Constantinos
Georgakopoulos, Stavros
Abrégé
Ultrawideband (UWB) beamforming networks are provided. A UWB beamforming network can have azimuth angle scanning and elevation angle scanning. A modified version of the Blass matrix topology can be used to achieve two-dimensional (2D) scanning behavior. The beamforming network can simultaneously excite a plurality of beams, and each of these beams can be at any chosen frequency inside the bandwidth that the beamformer covers. Each beam can be designed to point at any arbitrary direction, which can be defined by the desired elevation angle and azimuth angle, in the 2D plane.
H01Q 3/40 - Dispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la phase relative ou l’amplitude relative et l’énergie d’excitation entre plusieurs éléments rayonnants actifsDispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la distribution de l’énergie à travers une ouverture rayonnante faisant varier la phase par des moyens électriques avec une matrice faisant varier l'angle de déphasage
H01Q 3/26 - Dispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la phase relative ou l’amplitude relative et l’énergie d’excitation entre plusieurs éléments rayonnants actifsDispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la distribution de l’énergie à travers une ouverture rayonnante
H01Q 3/30 - Dispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la phase relative ou l’amplitude relative et l’énergie d’excitation entre plusieurs éléments rayonnants actifsDispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la distribution de l’énergie à travers une ouverture rayonnante faisant varier la phase
H01Q 3/34 - Dispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la phase relative ou l’amplitude relative et l’énergie d’excitation entre plusieurs éléments rayonnants actifsDispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la distribution de l’énergie à travers une ouverture rayonnante faisant varier la phase par des moyens électriques
The Florida International University Board of Trustees (USA)
Inventeur(s)
Kaddour, Abdul-Sattar
Georgakopoulos, Stavros
Abrégé
Antenna arrays with three-dimensional (3D) conformal radiating elements are provided, as well as methods of manufacturing and methods of using the same. An array can include a ground plane and a plurality of unit cells disposed thereon. Each unit cell can include a 3D conformal radiating element. The 3D conformal radiating elements can be, for example, patches (e.g., circular 3D patches), dipoles, or loops, and each radiating element is conformal on a hemispherical shape.
H01Q 5/48 - Combinaisons de plusieurs antennes de type dipôle
H01Q 3/46 - Lentilles actives ou réseaux réfléchissants
H01Q 15/04 - Dispositifs de réfraction ou diffraction, p. ex. lentille, prisme comportant un canal ou des canaux guide d'onde limités par des surfaces conductrices sensiblement perpendiculaires au vecteur champ électrique de l'onde, p. ex. lentille guide d'ondes à plaques parallèles
H01Q 21/06 - Réseaux d'unités d'antennes, de même polarisation, excitées individuellement et espacées entre elles
H01Q 21/20 - Réseaux d'unités d'antennes, de même polarisation, excitées individuellement et espacées entre elles les unités étant espacées le long d'un trajet curviligne ou adjacent à celui-ci
H01Q 21/26 - Antennes tourniquet ou similaires comportant des dispositions de trois éléments ou plus allongés disposés radialement et symétriquement dans un plan horizontal par rapport à un centre commun
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Zekios, Constantinos L.
Georgakopoulos, Stavros
Russo, Nicholas E.
Abrégé
Multi-band, microstrip patch antennas, as well as methods of fabricating the same and methods of using the same, are provided. A decoupling technique can be used where strategically etched slots are provided between the tightly coupled microstrip patch antennas, and the appropriate mode excitation of the corresponding patch antennas can be used. The antennas have high isolation between the frequency bands of operation. Multi-band operation can be achieved by exciting a different mode on each contiguous portion of the patch antenna.
The Florida International University Board of Trustees (USA)
Inventeur(s)
Hamza, Muhammad
Georgakopoulos, Stavros
Zekios, Constantinos L.
Abrégé
Ultra-wideband (UWB) arrays that are fully planar are provided. Fully-planar inverted-L element (FILE) arrays that are tightly coupled arrays (TCAs) can realize UWB tightly coupled apertures in the W and higher millimeter wave (mmWave) bands. The unit cell architecture of the FILE array, (which can have any desired size, can be comprised of an inverted-L shaped antenna and a capacitively coupled via-fence.
H01Q 21/06 - Réseaux d'unités d'antennes, de même polarisation, excitées individuellement et espacées entre elles
H01Q 1/40 - Éléments rayonnants recouverts avec, ou enrobés d'une matière protectrice
H01Q 5/25 - Systèmes à ultralarge bande, p. ex. systèmes à résonnance multipleSystèmes à impulsions
H01Q 9/42 - Antennes résonnantes avec alimentation à l'extrémité d'un élément actif allongé, p. ex. unipôle avec éléments repliés, les parties repliées étant espacées l'une de l'autre d'une petite fraction de la longueur d'onde émise
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
UNIVERSITY OF FLORENCE (Italie)
Inventeur(s)
Sackstein, Robert
Richichi, Barbara
Martin, Kyle
Abrégé
Provided are compositions and methods for specific fucosyltransferase inhibition for treatment of a variety of diseases. The compositions of the invention comprise a glycomimetic of L-Fucose that selectively inhibits the generation of sialyl Lewis X by FTVI and FTVH but has no effect on the generation of Lewis X by FTIX.
A61K 31/395 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines
A61K 31/343 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à cinq chaînons avec un oxygène comme seul hétéro-atome d'un cycle, p. ex. isosorbide condensés avec un carbocycle, p. ex. coumarane, bufaralol, béfunolol, clobenfurol, amiodarone
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (USA)
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (USA)
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Huang, Shar-Yin, Naomi
Pommier, Yves, Georges
Wang, Wenjie
Saha, Sourav
Wang, Weidong
Zhang, Tianyi
Brosh, Robert
Sommers, Joshua
Kennedy, Debbie
Shi, Pei-Yong
Garcia-Blanco, Mariano
Tse-Dinh, Yuk-Ching
Abrégé
Methods and polymethine bridge-containing cyanine compositions for inhibiting topoisomerase III beta (TOP3B), RNA-dependent RNA polymerases, and RNA-dependent DNA polymerases and conferring antiviral and/or anti-cancer activity are disclosed.
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Adjouadi, Malek
Eslami, Mohammad
Tabarestani, Solale
Abrégé
Systems and methods are provided for color-coded visualization to aid in diagnosis and prognosis of Alzheimer's disease (AD). The color-coded visualization mechanism can be driven by an integrated machine learning (ML) model, which can take as its inputs neuroimaging (e.g., magnetic resonance imaging (MRI), positron emission tomography (PET)) data, neuropsychological test scores, the cerebrospinal fluid (CSF) biomarker, and/or risk factors. With these inputs, the ML model can generate a color-coded visualization of the disease state.
G06V 10/77 - Traitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source
G06V 10/80 - Fusion, c.-à-d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
97.
System and method for real-time ultrabroadband wireless communications
A system and corresponding method may be employed for real-time ultrabroadband wireless communications. The system comprised a plurality of in-phase and quadrature (IQ) mixers that produce, in real-time on a per-channel basis, sub-channel signals from respective analog baseband IQ signals representing respective portions of user data. The system further comprises a power combiner. The power combiner produces a multi-channel output signal by frequency multiplexing, in real-time, the sub-channel signals produced. The multi-channel output signal represents the user data in its entirety and may be a real-time, multi-GHz wireless signal.
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Moon, Joong Ho
Miranda, Michelle
Abrégé
The subject invention provides oligo(carbamoylated guanidine)s (OCGs) having fast and selective mycobactericidal effects via disruption of the mycobacterial membrane potential. OCGs also potentiates bedaquiline, an oxidative phosphorylation-targeting anti-TB drug. The combination of OCG and anti-TB drug can be used as an effective therapy for treating tuberculosis.
A61P 31/06 - Agents antibactériens pour le traitement de la tuberculose
C07C 279/12 - Dérivés de la guanidine, c.-à-d. composés contenant le groupe les atomes d'azote liés par des liaisons simples ne faisant pas partie de groupes nitro ou nitroso ayant des atomes d'azote de groupes guanidine liés à des atomes de carbone acycliques d'un squelette carboné étant substitué de plus par des atomes d'azote ne faisant pas partie de groupes nitro ou nitroso
C07D 295/215 - Radicaux dérivés d'analogues azotés de l'acide carbonique
C08G 65/00 - Composés macromoléculaires obtenus par des réactions créant une liaison éther dans la chaîne principale de la macromolécule
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Jung, Ranu
Thota, Anil
Abrégé
Systems, devices, and methods for implanting target-specific multiple intrafascicular electrodes in peripheral nerves are provided to facilitate an implantation process that can reduce the difficulty of the implanting procedure and the time taken to implement the procedure. A longitudinal intrafascicular electrode implantation facilitator (LIFT) and a method for utilization of the LIFT for intrafascicular electrode implantation are provided. The LIFT can flatten the nerve to increase access to the number of fascicles available for implantation and supports the nerve during electrode implantation.
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (USA)
Inventeur(s)
Leng, Fenfei
Abrégé
E. coli exonuclease I and/or III. A method of converting the single-stranded circular DNA molecules into double-stranded circular DNA molecules is also described. The single-stranded and double-stranded circular DNA molecules can be used in a variety of applications.