This invention provides a histologic system and method for rapidly and accurately assessing tumor margins for the presence or absence of tumor using machine learning algorithms. This affords a rapid and accurate histologic tumor readout and increase process efficiency and decreases the chance for human error. Advantageously and uniquely, the system and method allows for analyzing the tissue section as complete or incomplete as the first criteria to determine whether a tissue section is clear of tumor. A machine learning process receives whole slide images (WSI) of tissue and determines (a) if each image of the WSI contains complete/incomplete tissue samples and (b) if each image of the WSI contains tumorous tissue or an absence thereof. A reconstruction process generates a model of the tissue that maps types of tissue therein, and a display process provides results of the model or report for use and manipulation by a user.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
G06Q 20/10 - Architectures de paiement spécialement adaptées aux systèmes de transfert électronique de fondsArchitectures de paiement spécialement adaptées aux systèmes de banque à domicile
G06Q 30/018 - Certification d’entreprises ou de produits
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p. ex. leur création ou leur transmission
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
G16H 70/60 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des pathologies
A template that includes a support structure pivotably mounted to a guide, wherein the guide includes a compass with angle markings, a first guide member extending from the vertex of the compass, a second guide member extending from the vertex of the compass. In another embodiment, a medical imaging system can include a medical imaging machine with a display screen, a support structure affixed to the medical imaging machine, and a guide pivotably mounted to the support structure. A method of aligning medical implants with anatomical structures includes positioning a template over the display screen, and comparing an angle of a medical tool or implant relative to the anatomical structure of the patient to a reference angle on the guide and installing the implant in the patient at the angle indicated by the guide.
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
3.
System and method for providing a rapid virtual diagnostic companion for use in diagnosis of cancer and related conditions using immunohistochemistry based upon a neural network
This provides a system and method for analyzing and diagnosing conditions, such as cancer, based upon stained tissue sample slides prepared by users from patient tissue taken, for example, in a biopsy procedure. A convolutional neural network (CNN) is generated at training time. Slide images are acquired/scanned, and individual cell nuclei from the images are annotated, using IHC. H&E images are acquired/scanned prior to a washout intermediate step from the same slides/tissue samples. IHC is performed on the same tissue layer, which was scanned and used to retrospectively annotate the H&E WSI. IHC is used to annotate a ground truth mask for machine learning. The resultant process achieves a high degree of spatial resolution in detecting individual IHC positive nuclei, yielding process that is almost entirely automated, employing materials that are commonly available in clinical practice. In runtime, users access the CNN to perform analysis on patient slides.
This invention provides a device and treatment method for replacing the hip (in either a hemiarthroplasty or total hip arthroplasty), which protects the remainder of the femur from fracture. Such a device is highly applicable to the treatment of patients with current or impending fractures of the femur, particularly those with metastatic bone cancer, where there is concern for current or future metastatic disease of the femoral neck or head, which would necessitate hip replacement. The implant consists of a two-piece arrangement with a separate femoral component and a securing, intermedullary rod/nail that is received in a locking arrangement by a longitudinal fenestration of the femoral component.
A system and method for delivering diagnostic information to a user in an automated manner. An image processing module reads magnified raw image data from whole slides containing tissue cells. A background deletion process identifies and isolates cell images. A neural network, which is trained based upon image data, classifies the cell images. The classification uses specialist criteria to categorize/segment the cell images into a plurality of discrete cell types. A display process provides the diagnostic information to the user. The neural network can be trained using a plurality of cell types each having the specialist criteria. The diagnostic information includes filtered and/or reorganized images of the tissue cells. Additionally, the user can request the diagnostic information based upon an account that provides payment according to a predetermined formula associated with at least one of a type, format, and timing of information delivered to the user.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G01N 15/1433 - Traitement du signal utilisant la reconnaissance d’image
G06F 18/214 - Génération de motifs d'entraînementProcédés de Bootstrapping, p. ex. ”bagging” ou ”boosting”
G06F 18/40 - Dispositions logicielles spécialement adaptées à la reconnaissance des formes, p. ex. interfaces utilisateur ou boîtes à outils à cet effet
This invention provides a histologic system and method for rapidly and accurately assessing tumor margins for the presence or absence of tumor using machine learning algorithms. This affords a rapid and accurate histologic tumor readout and increase process efficiency and decreases the chance for human error. Advantageously and uniquely, the system and method allows for analyzing the tissue section as complete or incomplete as the first criteria to determine whether a tissue section is clear of tumor. A machine learning process receives whole slide images (WSI) of tissue and determines (a) if each image of the WSI contains complete/incomplete tissue samples and (b) if each image of the WSI contains tumorous tissue or an absence thereof. A reconstruction process generates a model of the tissue that maps types of tissue therein, and a display process provides results of the model or report for use and manipulation by a user.
G06Q 20/10 - Architectures de paiement spécialement adaptées aux systèmes de transfert électronique de fondsArchitectures de paiement spécialement adaptées aux systèmes de banque à domicile
G06Q 30/018 - Certification d’entreprises ou de produits
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p. ex. leur création ou leur transmission
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
G16H 70/60 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des pathologies
A system for a trajectory and aiming guide for use with fluoroscopy is comprised of a ring holder is with a plurality of connecting arms, a radiolucent ring disk with an outer perimeter wall and a central axle on the bottom surface of the ring disk; a first rotatable disk located below the ring holder and comprised of a handle, a radiolucent disk ring with a central cutout to receive the central axle, the material of the disk comprising an embedded array of a plurality of radiopaque wires and an outer perimeter wall; a second rotatable disk located below the first rotatable disk and comprised of a handle, a radiolucent disk ring with a central cutout to receive the central axle, the material of the disk comprising an embedded array of a plurality of radiopaque wires and an outer perimeter wall; and a locking cap for the axle.
A61B 17/17 - Dispositifs de guidage pour les forets
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A system and method for installation of a k-wire through a scaphoid or other fractured bone can include a guide block for accurate trajectory of a k-wire. A support frame for a guide block can be casted and/or secured into place, and a CT scan is obtained, so the fractured bone and the location of the window can be known in the same three-dimensional space. An ideal k-wire trajectory can be plotted through the fractured bone, and a guide block with a lumen can be designed and printed using a three-dimensional printer. The guide block can be inserted into the frame so the lumen aligns with the ideal k-wire trajectory, and a k-wire can be inserted through the lumen into the fractured bone. The net effect would be ideal placement of the k-wire that would facilitate the ultimate insertion of a percutaneous screw to provide fixation of the fractured bone.
A61B 17/88 - Moyens ou procédés pour implanter ou pour extraire des dispositifs de fixation interne
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A61B 90/10 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures pour la chirurgie stéréotaxique, p. ex. système stéréotaxique à cadre
A61B 90/11 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures pour la chirurgie stéréotaxique, p. ex. système stéréotaxique à cadre avec des guides pour aiguilles ou instruments, p. ex. des glissières courbes ou des articulations à rotule
A61B 90/14 - Fixateurs pour parties du corps, p. ex. clamps crâniensDétails de construction des fixateurs, p. ex. broches
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A61B 17/56 - Instruments ou procédés chirurgicaux pour le traitement des os ou des articulationsDispositifs spécialement adaptés à cet effet
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
9.
Screen-mounted trajectory and aiming guide for use with fluoroscopy
A template that includes a support structure pivotably mounted to a guide, wherein the guide includes a compass with angle markings, a first guide member extending from the vertex of the compass, a second guide member extending from the vertex of the compass. In another embodiment, a medical imaging system can include a medical imaging machine with a display screen, a support structure affixed to the medical imaging machine, and a guide pivotably mounted to the support structure. A method of aligning medical implants with anatomical structures includes positioning a template over the display screen, and comparing an angle of a medical tool or implant relative to the anatomical structure of the patient to a reference angle on the guide and installing the implant in the patient at the angle indicated by the guide.
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
10.
System and method to measure pain levels of patients following surgery
This invention provides a non-invasive system for measuring pain level in a body at a site containing a predetermined concentration of magnetic nanoparticles. A drive coil and a pickup coil transmit and measure a field passing through the site based upon response of the magnetic nanoparticles, and a processor computes a pain level based upon variations in the field. The pain level can be indexed to an absolute scale that affords more predictability and objectivity in determining true pain level. Illustratively, the processor derives values for levels of cytokine IL-6, SP and temperature at the site, which are translated into the pain level. In an embodiment, the system and method can be implemented in a handheld device in which the drive coil and pickup coil reside in a housing.
A support rig for a medical instrument can hold a medical instrument that is inserted into a patient in a fixed position and orientation relative to patient, so that the position and orientation of the medical instrument is not affected by the breathing or other motion of the patient. The support rig and medical instrument can be radiolucent and non-metallic, so that an image can be taken of the patient while the medical instrument is inserted in the patent and held by the support rig. The radiolucent support rig and medical instrument can allow for imaging, including x-ray, CT, and/or MRI, to occur simultaneously during the surgery. Surgical outcomes can be improved by using imaging to provide information about a tumor and/or anatomical structures during surgery.
A61B 1/24 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour la bouche, c.-à-d. stomatoscopes, p. ex. portant des abaisse-langueInstruments pour ouvrir la bouche ou la maintenir ouverte
A61B 17/02 - Instruments, dispositifs ou procédés chirurgicaux pour maintenir les blessures ouvertes, p. ex. rétracteursÉcarteurs
A61B 1/267 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour les voies respiratoires, p. ex. laryngoscopes, bronchoscopes
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A61B 6/14 - Applications ou adaptations à l'art dentaire
13.
SYSTEM AND METHOD FOR IMAGE GUIDED TRANSORAL ROBOTIC SURGERY USING AN IMAGING COMPATIBLE ORAL RETRACTOR SYSTEM
A support rig for a medical instrument can hold a medical instrument that is inserted into a patient in a fixed position and orientation relative to patient, so that the position and orientation of the medical instrument is not affected by the breathing or other motion of the patient. The support rig and medical instrument can be radiolucent and non-metallic, so that an image can be taken of the patient while the medical instrument is inserted in the patent and held by the support rig. The radiolucent support rig and medical instrument can allow for imaging, including x-ray, CT, and/or MRI, to occur simultaneously during the surgery. Surgical outcomes can be improved by using imaging to provide information about a tumor and/or anatomical structures during surgery.
A61B 1/24 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour la bouche, c.-à-d. stomatoscopes, p. ex. portant des abaisse-langueInstruments pour ouvrir la bouche ou la maintenir ouverte
14.
NASAL GUARD FOR USE DURING NASAL SINUS AND SKULL BASE SURGERY
This invention provides a nasal guard, which can be constructed according to various manufacturing techniques (e.g. molding. 3D printing, etc.) for use during nasal sinus and skull base surgery to reduce aerosolized transmission to protect surgical staff, conserve the volatile supply of personal protective equipment (PPE) and reduce the introduction of particles into the operating room. The novel nasal guard, according to embodiments of this invention, can be readily applied to the patient's nose/nasal region during surgery and, while exposing the nostrils for access by surgical procedures, reduces aerosol emission from the nares. This allows for an adequate seal on a variety of face sizes/shapes without impeding access for surgical tools and/or does not otherwise interfere with surgical approach. The nasal guard herein is also compatible with standard suction equipment. The nasal guard is easy-to-use and ergonomic, and can be (is) constructed from biocompatible materials.
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A61B 17/24 - Instruments, dispositifs ou procédés chirurgicaux pour la cavité buccale, le larynx, les conduits des bronches ou le nezGrattoirs pour la langue
15.
NASAL GUARD FOR USE DURING NASAL SINUS AND SKULL BASE SURGERY
This invention provides a nasal guard, which can be constructed according to various manufacturing techniques (e.g. molding. 3D printing, etc.) for use during nasal sinus and skull base surgery to reduce aerosolized transmission to protect surgical staff, conserve the volatile supply of personal protective equipment (PPE) and reduce the introduction of particles into the operating room. The novel nasal guard, according to embodiments of this invention, can be readily applied to the patient's nose/nasal region during surgery and, while exposing the nostrils for access by surgical procedures, reduces aerosol emission from the nares. This allows for an adequate seal on a variety of face sizes/shapes without impeding access for surgical tools and/or does not otherwise interfere with surgical approach. The nasal guard herein is also compatible with standard suction equipment. The nasal guard is easy- to-use and ergonomic, and can be (is) constructed from biocompatible materials.
A61B 1/233 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour le nez, c.-à-d. nasoscopes
A61B 17/24 - Instruments, dispositifs ou procédés chirurgicaux pour la cavité buccale, le larynx, les conduits des bronches ou le nezGrattoirs pour la langue
A61B 34/00 - Chirurgie assistée par ordinateurManipulateurs ou robots spécialement adaptés à l’utilisation en chirurgie
16.
System and method for automatic detection of vertebral fractures on imaging scans using deep networks
This invention provides systems and methods that can detect incidental OVFs in CT examinations at the level of practicing radiologists. The OVF detection system leverages a deep convolutional neural network (CNN) to extract radiological features from each CT scan slice. These extracted features are processed through a feature aggregation module to make the final diagnosis for the full CT scan. Feature aggregation, can be performed in a variety of ways, including the use of a long short-term memory (LSTM) network. In one example, the CNN can be trained on a predetermined number of CT scans, which are established as reference standards. This result can effectively the performance of practicing radiologists on this test set in real world clinical circumstances. The system and method can be employed to assist and improve OVF diagnosis in clinical settings by pre-screening routine CT examinations and flagging suspicious cases prior to review by radiologists.
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
17.
Screen-mounted trajectory and aiming guide for use with fluoroscopy
A template that includes a support structure pivotably mounted to a guide, wherein the guide includes a compass with angle markings, a first guide member extending from the vertex of the compass, a second guide member extending from the vertex of the compass. In another embodiment, a medical imaging system can include a medical imaging machine with a display screen, a support structure affixed to the medical imaging machine, and a guide pivotably mounted to the support structure. A method of aligning medical implants with anatomical structures includes positioning a template over the display screen, and comparing an angle of a medical tool or implant relative to the anatomical structure of the patient to a reference angle on the guide and installing the implant in the patient at the angle indicated by the guide.
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A61B 17/17 - Dispositifs de guidage pour les forets
A61B 90/50 - Supports pour instruments chirurgicaux, p. ex. bras articulés
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
18.
Mobile shield for protection from projectiles and radiation
A mobile radiation and ballistic shield can include a central shield with an outer layer of steel and a second layer of lead, and a chassis having front wheels and rear wheels. One or more auxiliary shields can be hinged outward from the central shield into a deployed position to increase ballistic coverage, and can be hinged inward to decrease the width of the mobile radiation and ballistic shield to pass through doorways and elevators.
This invention provides a histologic system and method for rapidly and accurately assessing tumor margins for the presence or absence of tumor using machine learning algorithms. This affords a rapid and accurate histologic tumor readout and increase process efficiency and decreases the chance for human error. Advantageously and uniquely, the system and method allows for analyzing the tissue section as complete or incomplete as the first criteria to determine whether a tissue section is clear of tumor. A machine learning process receives whole slide images (WSI) of tissue and determines (a) if each image of the WSI contains complete/incomplete tissue samples and (b) if each image of the WSI contains tumorous tissue or an absence thereof. A reconstruction process generates a model of the tissue that maps types of tissue therein, and a display process provides results of the model or report for use and manipulation by a user.
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 70/60 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des pathologies
G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p. ex. leur création ou leur transmission
This invention provides a histologic system and method for rapidly and accurately assessing tumor margins for the presence or absence of tumor using machine learning algorithms. This affords a rapid and accurate histologic tumor readout and increase process efficiency and decreases the chance for human error. Advantageously and uniquely, the system and method allows for analyzing the tissue section as complete or incomplete as the first criteria to determine whether a tissue section is clear of tumor. A machine learning process receives whole slide images (WSI) of tissue and determines (a) if each image of the WSI contains complete/incomplete tissue samples and (b) if each image of the WSI contains tumorous tissue or an absence thereof. A reconstruction process generates a model of the tissue that maps types of tissue therein, and a display process provides results of the model or report for use and manipulation by a user.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p. ex. leur création ou leur transmission
G16H 70/60 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des pathologies
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
G06Q 30/018 - Certification d’entreprises ou de produits
G06Q 20/10 - Architectures de paiement spécialement adaptées aux systèmes de transfert électronique de fondsArchitectures de paiement spécialement adaptées aux systèmes de banque à domicile
A system for a trajectory and aiming guide for use with fluoroscopy is comprised of a ring holder is with a plurality of connecting arms, a radiolucent ring disk with an outer perimeter wall and a central axle on the bottom surface of the ring disk; a first rotatable disk located below the ring holder and comprised of a handle, a radiolucent disk ring with a central cutout to receive the central axle, the material of the disk comprising an embedded array of a plurality of radiopaque wires and an outer perimeter wall; a second rotatable disk located below the first rotatable disk and comprised of a handle, a radiolucent disk ring with a central cutout to receive the central axle, the material of the disk comprising an embedded array of a plurality of radiopaque wires and an outer perimeter wall; and a locking cap for the axle.
A61B 17/17 - Dispositifs de guidage pour les forets
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A collapsible pessary is provided, and can have a stem and at least one rotating petal member that can rotate between a collapsed state with a smaller diameter and a deployed state with a larger diameter. The collapsible pessary can have a plunger within the stem, and pushing the plunger upwards can cause the plunger to push upwards on a portion of the petal member, thereby causing the petal member to rotate into a deployed position. The pessary can be in a collapsed state wherein its overall diameter is at a minimum, or a deployed state, wherein its overall diameter is at a maximum.
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
A61M 31/00 - Dispositifs pour l'introduction ou la rétention d'agents, p. ex. de remèdes, dans les cavités du corps
A61F 6/12 - Dispositifs pour les introduire ou les enlever
A system for an acetabular cup alignment includes a mounting element; a first pivot; a first support arm, the first support arm being axially rotatable relative to the first pivot; a second pivot; a second support arm that is attached to the second pivot at an end, the second support arm being axially rotatable relative to the second pivot; a third pivot; a third support arm that is attached to the third pivot at an end, the third support arm being axially rotatable relative to the third pivot; a red laser housing that is provided with at least one red laser light emitter, the red laser housing being attached to the second pivot; and a green laser housing that is provided with at least one green laser light emitter, the green laser housing being attached to the third support arm.
A61B 17/58 - Instruments ou procédés chirurgicaux pour le traitement des os ou des articulationsDispositifs spécialement adaptés à cet effet pour ostéosynthèse, p. ex. plaques, vis ou matériels de fixation
A61B 17/60 - Instruments ou procédés chirurgicaux pour le traitement des os ou des articulationsDispositifs spécialement adaptés à cet effet pour ostéosynthèse, p. ex. plaques, vis ou matériels de fixation pour l'ostéosynthèse externe, p. ex. appareils étireurs ou constricteurs
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
A61F 2/46 - Outils particuliers pour l'implantation des articulations artificielles
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
A method and system for targeting antigens unique to a tumor site. The method can include a first phase of monoclonal antibodies that bind to the tumor site. A second phase of monoclonal antibodies can be administered that bind to the first phase. A third phase of monoclonal antibodies can be administered that bind to the second phase. The third phase can include radionuclides to allow the tumor site to be imaged. Once identified, a phase of toxins can be administered, resulting in death of the tumor cells.
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p. ex. par les adjuvants chimiques
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A61K 39/40 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire bactériens
A61K 51/10 - Anticorps ou immunoglobulinesLeurs fragments
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
26.
Gauge for determining nostril deformity and method for using the same
This invention provides a novel nostril gauge system and methods for using the same, which allows the practitioner to measure the size of deformed nostrils resulting from any cause such as from a cleft lip and/or cleft palate, a traumatic injury, an infectious process, a prior surgical intervention, etc. The device allows for the expeditious and accurate measurement of the size/caliber of normal and deformed nostrils before any type of nasal reconstruction intended to correct asymmetric nostril openings (nares). The gauge includes a series of measured and accurately sized gauge steps that are readily used and result in a more precise nostril sizing. The gauge includes a plurality of spines, each having steps thereon correlating to different circumferential sizes. The gauge system is provided with printed size indicia that refers to each gauge step and facilitates the measuring process. In illustrative embodiments, the gauge body defines a loop with a plurality of gauge spines, arranged around its perimeter. The axial depth of every gauge step is sufficient to adequately engage the nostril during sizing. Every step can be identified by indicium that is correlated to that particular diameter. In another embodiment, the spines can be mounted orthogonally at the ends of arms arranged like spokes of a wheel about the perimeter of a body.
A61B 5/107 - Mesure de dimensions corporelles, p. ex. la taille du corps entier ou de parties de celui-ci
A61B 17/24 - Instruments, dispositifs ou procédés chirurgicaux pour la cavité buccale, le larynx, les conduits des bronches ou le nezGrattoirs pour la langue
G01B 3/34 - Bagues ou autres calibres à ouverture, p. ex. calibres à tolérances maxima et minima
27.
System and method for supporting a patient for imagery during surgery
An system for supporting a patient during a medical procedure including a pedestal supported from a base surface; a ring structure mounted over the pedestal, the ring structure includes inner and outer ring members that are arranged for relative rotation therebetween. An elongated support platform, upon which the patient is supported, is also provided, as well as a bar member for mounting one end of the support platform to the inner ring of the ring structure while the opposite end of the support platform is free so as to be disposed in a cantilever manner from the ring structure. The roll of the support platform is controlled by rotating the inner ring relative to the outer ring, the pitch of the support platform by pivoting the bar member relative to the inner ring, and the yaw of the support platform by rotating the ring structure relative to the pedestal.
Generally discussed herein are systems, apparatuses, and methods that relate to detecting an error in a laboratory analyzer. A device may include an average of deltas (AoD) module to receive pairs of consecutive measurement values of an analyte of one or more patients, each pair of consecutive measurement values including a first measurement of an analyte obtained from a patient of the one or more patient at a first time and a second measurement of an analyte obtained from the patient at a second time after the first time, determine a time delta between each pair of consecutive measurement values, determine whether the time delta is within a specified time window, determine a measurement value deltas between each pair of consecutive measurement values that includes a time delta with the specified time window, and determine an AoD using the determined measurement value deltas.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G04F 10/00 - Appareils pour mesurer des intervalles de temps inconnus par des moyens électriques
A safety syringe that effectively prevents the administration of an injection in excess of a maximum injection pressure, and that provides a clear, immediate tactile feedback to the practitioner each time a maximum injection pressure is exceeded. The practitioner is provided a predetermined number of attempts to inject fluid without exceeding the maximum injection pressure, each time receiving a direct tactile feedback in the form of a ratcheting click within the plunger assembly of the syringe. After a final attempt, the next over-pressure event causes a disconnect between the thumb plate of the syringe and the piston that engages the fluid within the syringe barrel, positively prevent a potentially harmful injection. In an illustrative embodiment, the plunger assembly includes a distal portion connected to the piston and a proximal portion, connected to the thumb plate.
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras
30.
Intravascular needle and catheter assembly and grip for the same
A needle, catheter, and housing assembly is provided. The assembly includes a slider portion that slides relative to the housing. The slider portion can be actuated by a caregiver/operator such that a catheter can be threaded into a patient with simple movement of the operator's thumb or other finger. The assembly also includes an improved flash chamber. The flash chamber utilizes capillary action and/or a visible portal area to provide a caregiver/operator with more immediate information as to whether the needle has been inserted in the vein or artery.
An intravascular needle and catheter arrangement that ensures flashback is indicated after the catheter is safely inserted through the needle puncture in the vascular wall and emplaced into the vessel. This placement location, at which flashback first occurs is sufficient to begin threading the catheter without risk of over-insertion or under-insertion. The catheter overlies a needle having a distal tip that defines a point. The needle tip includes an enclosed distal-most end and a port located along at least one of the proximal portion of the point and an adjacent cylindrical sidewall of the needle. The distal end of the catheter exposes the port for entry of blood from a vessel thereinto only after the distal end of the catheter has entered sufficiently into the interior of the vessel. An opposing second side of the tip defines a curved surface that prevents puncturing of the back vessel wall.
A61M 25/06 - Aiguilles avec un guide pour piquer le corps ou analogues
A61M 5/32 - AiguillesParties constitutives des aiguilles relatives au raccordement de celles-ci à la seringue ou au manchonAccessoires pour introduire l'aiguille dans le corps ou l'y maintenirDispositifs pour la protection des aiguilles
A system and method for confirming the proper placement of a penetrating catheter into a venous region using principles of oximetry in which blood is subjected to light of a plurality of wavelengths and detected for absorption levels. The result is analyzed by a processor and the level oxygen saturation of the blood is indicated. The characteristic level of saturation informs the practitioner whether oxygenated arterial blood is present due to an inadvertent puncture. The catheter is introduced using an introduction needle and thereafter removed to allow blood to communicate with sensing elements that consist of a light-emitter and opposed photodetector. Light in the infrared and visible red wavelengths can be provided by separate LED units. Aspiration of blood through the catheter by an attached syringe allows the processor to compute the level of oxygen saturation or other blood constituent, based upon detected light absorption of passing blood.
This invention provides a system and method for an assay used in determining appropriate immunosuppressant levels relative to organ transplant in which PBMC is separated from whole blood by Ficoll®. An aliquot of PBMC is used for phenotyping of cells. CD4, CD8, memory and naive subsets, B-cells regulatory T -cells and other cell markers (e.g. CD31) are examined. After an aliquot of PBMC is taken, CD4 cells are isolated. DNA is isolated from the cells. CD4 cells can be used for TREC at the defined time points. The TREC assay can be performed via a validated protocol. TREC levels are then measured using a quantitative RT-PCR for single jointed TREe. Alternatively, or additionally, TREC-correlated cell markers (e.g. CD31) can be analyzed. Normal control cells are run in parallel. A kit for performing the assay, including instructions and components.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
35.
System and method for venous oximetry using a catheter
This invention provides a system and method for confirming the proper placement of a penetrating catheter into a vascular compartment without undesirable arterial cannulation using principles of oximetry in which blood from the penetrated region is subjected to light of a plurality of wavelengths and detected for absorption levels. The result is analyzed by a processor and the level of oxygen saturation of the blood is indicated. The characteristic level of saturation informs the practitioner whether oxygenated arterial blood is present due to an inadvertent puncture. The catheter is introduced using an introduction needle. Thereafter the needle is removed to allow blood to communicate with sensing elements that consist of a light-emitting LED array and opposed photodetector. Light in the infrared and visible red wavelengths can be provided by separate LED units. Aspiration of blood through the catheter by an attached syringe allows the processor to compute the level of oxygen saturation, based upon detected light absorption of passing blood, using the Beer-Lambert law. The sensing elements can be miniaturized so as to be located in the distal tip of the catheter, and can be operatively connected to an external connector via embedded leads that connects a base unit with the processor and a display of saturation level. The catheter allows subsequent insertion of a guidewire and, after catheter removal a CVC.
An intravascular needle (300) and catheter (410) arrangement that ensures flashback is indicated after the catheter (410) is safely inserted through the needle puncture in the vascular wall and emplaced into the vessel. This placement location, at which flashback first occurs is sufficient to begin threading the catheter (410) without risk of over-insertion or under-insertion. The catheter (410) overlies a needle (300) having a distal tip (310) that defines a point (362). The needle tip (310) includes an enclosed distal-most end and a port (370) located along at least one of the proximal portion of the point (362) and an adjacent cylindrical sidewall (320) of the needle (300). The distal end (420) of the catheter (410) exposes the port (370) for entry of blood from a vessel thereinto only after the distal end (420) of the catheter (410) has entered sufficiently into the interior of the vessel. An opposing second side of the tip (310) defines a curved surface (340) that prevents puncturing of the back vessel wall.
This invention provides a female medical coupling port with an integrated port guide to enable more accurate and precise coupling of a male port coupling (such as the cannula of a syringe) and to prevent port exposure to non- sterile objects. The male and female ports can be arranged according to standard dimensions for male and female luer taper fittings recognized by ANSI and by ISO. This guide-shielded port is usable with the standard ANSI and ISO male cannula widely used in the medical field. In an embodiment the female port is used in medical fluid systems to receive a blunt male cannula, such as those found in the luer lock fitting of needle-less syringes and IV tubing systems to establish a mechanical coupling. Female ports allow coupling of devices (e.g. syringes and IV tubing) to a variety of medical applications including stopcocks, minimum fluid displacement medical couplings, female -to-female adapters, port dead¬ end caps, IV extension sets, pressure -monitoring devices, etc. The port guide can be constructed as a unitary part of the port, or can be a retro fittable structure that is either snapped into place on, for example, a female port stem, or slid onto a port, such as a minimum displacement fluid coupling. Appropriate drain ports can be provided in the port guide to prevent capture of excess fluid.
brevets
