Curable, and cured, fluorine-free, silicone adhesive release compositions; release liners comprising, consisting essentially of, or consisting of a substrate having a surface and a curable, and cured, fluorine-free, silicone adhesive release compositions on the substrate surface; and composites comprising, consisting essentially of, or consisting of a silicone adhesive and a release liner comprising a substrate having a surface and a cured, fluorine-free, silicone adhesive release composition on the substrate surface, wherein the adhesive resides on the cured, fluorine-free, silicone adhesive release composition; as well as related methods for their preparation and use.
B32B 27/28 - Produits stratifiés composés essentiellement de résine synthétique comprenant des copolymères de résines synthétiques non complètement couverts par les sous-groupes suivants
2.
FILLED POLYISOBUTENE-BASED PRESSURE SENSITIVE ADHESIVES AND METHODS FOR THEIR PREPARATION AND USE
Filled polyisobutene-based (PIB) pressure sensitive adhesives (PSA) comprising a crosslinked structure therein. Compositions for preparing the PSAs comprise a PIB resin, a surface-treated and/or non-surface treated filler, wherein the surface treatment comprises a silane, a silazane or a combination thereof, and a SiH, SH or isocyanate functional crosslinking agent. Related embodiments include methods for preparing and using the filled PSAs, e.g., barrier adhesives and as a component of an adhesive tape.
Transdermal delivery systems, such as patches. for certain direct factor Xa inhibitors (“FXa”), as well as methods for the manufacture and use of such transdermal patches. particularly in the treatment of thrombosis or in other conditions wherein an anticoagulant is desired. and to prevent stroke and embolism in people with atrial fibrillation (AF).
A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine
A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
A61K 47/12 - Acides carboxyliquesLeurs sels ou anhydrides
4.
FILLED POLYISOBUTENE-BASED PRESSURE SENSITIVE ADHESIVES AND METHODS FOR THEIR PREPARATION AND USE
Filled polyisobutene-based (PIB) pressure sensitive adhesives (PSA) comprising a polyisobutene resin and certain fillers, the fillers including silicas, aluminas, and/or acetylene (carbon) black (and optionally other fillers), as well as mixtures thereof. In certain embodiments the silica and alumina fillers are not surface-treated or otherwise modified, while in other embodiments, these fillers are surface-treated with a composition comprising an organosilane, an organosiloxane or an organosilazane, but remain unreacted in the finished PSA. The PIB PSAs may be used for a variety of applications, including as a barrier adhesive or as a component of a conductive, or non-conductive, tape.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Drug delivery agents in the form of dissolvable or erodible films that facilitate the oral, transmucosal or transdermal delivery of pharmaceutical preparations; drug delivery agents in the form of transdermal patches, oral thin films, topical gels, creams, ointments, and oral liquids that facilitate the delivery of pharmaceutical preparations Custom manufacture of pharmaceuticals; Custom of manufacture of drug delivery systems; Custom manufacture of oral dissolvable films; Custom manufacture of erodible films; Custom manufacture of transdermal patches; Custom manufacture of topical gels, creams or ointments, and oral liquids Oral thin films and transdermal drug delivery patches sold without medication Research and development services in the field of pharmaceutical preparations; Research and development in the field of drug delivery systems comprising dissolvable films, erodible films or transdermal patches, topical gels, creams or ointments, and oral liquids, containing pharmaceutically active ingredients for the release of a wide variety of therapeutic agents
05 - Produits pharmaceutiques, vétérinaires et hygièniques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Drug delivery agents in the form of dissolvable or erodible films that facilitate the oral, transmucosal or transdermal delivery of pharmaceutical preparations; drug delivery agents in the form of transdermal patches, oral thin films, topical gels, creams, ointments, and oral liquids that facilitate the delivery of pharmaceutical preparations Custom manufacture of pharmaceuticals; Custom of manufacture of drug delivery systems; Custom manufacture of oral dissolvable films; Custom manufacture of erodible films; Custom manufacture of transdermal patches; Custom manufacture of topical gels, creams or ointments, and oral liquids Oral thin films and transdermal drug delivery patches sold without medication Research and development services in the field of pharmaceutical preparations; Research and development in the field of drug delivery systems comprising dissolvable films, erodible films or transdermal patches, topical gels, creams or ointments, and oral liquids, containing pharmaceutically active ingredients for the release of a wide variety of therapeutic agents
Disclosed herein are methods of administering relatively high doses of dexmedetomidine or a pharmaceutically acceptable salt thereof to a human subject, without also inducing significant sedation. The disclosed methods are particularly suitable for the treatment of agitation, especially when associated with neurodegenerative and/or neuropsychiatric diseases such as schizophrenia, bipolar illness such as bipolar disorder or mania, dementia, depression, or delirium.
Disclosed herein is a self-supporting, dissolvable, film containing dexmedetomidine or a pharmaceutically acceptable salt thereof. The film is administered orally to treat various conditions, particularly agitation, by transmucosal delivery of the active agent.
A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
Disclosed herein is a self-supporting, dissolvable, film containing dexmedetomidine or a pharmaceutically acceptable salt thereof. The film is administered orally to treat various conditions, particularly agitation, by transmucosal delivery of the active agent.
A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
Filled polyisobutene-based (PIB) pressure sensitive adhesives (PSA) comprising a crosslinked structure therein. Compositions for preparing the PSAs comprise a PIB resin, a surface-treated and/or non-surface treated filler, wherein the surface treatment comprises a silane, a silazane or a combination thereof, and a SiH, SH or isocyanate functional crosslinking agent. Related embodiments include methods for preparing and using the filled PSAs, e.g., barrier adhesives and as a component of an adhesive tape.
Transdermal delivery systems, such as patches, for certain direct factor Xa inhibitors ("FXa"), as well as methods for the manufacture and use of such transdermal patches, particularly in the treatment of thrombosis or in other conditions wherein an anticoagulant is desired, and to prevent stroke and embolism in people with atrial fibrillation (AF).
A61K 31/166 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome de carbone d'un groupe carboxamide lié directement au cycle aromatique, p. ex. procaïnamide, procarbazine, métoclopramide, labétalol
Dissolvable unit dose film constructs are made by providing a muco-adhesive composition including a muco-adhesive polymer matrix in which the muco-adhesive polymer matrix has a water-soluble polymer, water-dispersible polymer, water-swellable polymer, or combinations thereof and a liquid carrier. The method further includes drying the muco-adhesive composition to remove at least a portion of the liquid carrier, forming a muco-adhesive film substrate, forming a composition for an active layer, the composition including a polymer matrix in which the polymer matrix for the active layer composition includes a water-soluble polymer, water-dispersible polymer, water-swellable polymer, or combinations thereof, an active ingredient and a liquid carrier. The method further includes depositing the composition for the active layer onto the muco-adhesive substrate as a plurality of individual volumes and removing the liquid carrier from the plurality of deposited individual volumes to form a plurality of dissolvable film active layers on the muco-adhesive substrate.
Filled polyisobutene-based (PIB) pressure sensitive adhesives (PSA) comprising a polyisobutene resin and certain fillers, the fillers including silicas, aluminas, and/or acetylene (carbon) black (and optionally other fillers), as well as mixtures thereof. In certain embodiments the silica and alumina fillers are not surface-treated or otherwise modified, while in other embodiments, these fillers are surface-treated with a composition comprising an organosilane, an organosiloxane or an organosilazane, but remain unreacted in the finished PSA. The PIB PSAs may be used for a variety of applications, including as a barrier adhesive or as a component of a conductive, or non-conductive, tape.
Disclosed herein are methods of administering relatively high doses of dexmedetomidine or a pharmaceutically acceptable salt thereof to a human subject, without also inducing significant sedation. The disclosed methods are particularly suitable for the treatment of agitation, especially when associated with neurodegenerative and/or neuropsychiatric diseases such as schizophrenia, bipolar illness such as bipolar disorder or mania, dementia, depression, or delirium.
A UV light curable adhesive is disclosed, comprising, at least one bi-active monomer, at least one polymerizable oligomer, a primary photoinitiator, and a monomer scavenger, wherein photopolymerization of the at least one bi-active monomer by the primary photoinitiator activates the monomer scavenger, reducing residual monomer content in a cured adhesive formed by the photopolymerization of the bi-active monomer in comparison to an otherwise identical comparative UV adhesive lacking the monomer scavenger. A method for curing the UV light curable adhesive is disclosed, including applying the UV light curable adhesive to a surface and exposing the UV light curable adhesive to UV light, free from heating the UV light curable adhesive other than any autogenous increases in temperature from exothermic polymerization reactions. A device with the UV light cured adhesive is disclosed, including the UV light cured adhesive joining a first surface to a second surface.
C08F 2/48 - Polymérisation amorcée par énergie ondulatoire ou par rayonnement corpusculaire par la lumière ultraviolette ou visible
C08F 2/50 - Polymérisation amorcée par énergie ondulatoire ou par rayonnement corpusculaire par la lumière ultraviolette ou visible avec des agents sensibilisants
C09J 4/06 - Adhésifs à base de composés non macromoléculaires organiques ayant au moins une liaison non saturée carbone-carbone polymérisable en combinaison avec un composé macromoléculaire autre qu'un polymère non saturé des groupes
16.
UV light curable adhesive and device with UV light curable adhesive
A UV light curable adhesive is disclosed, comprising, at least one bi-active monomer, at least one polymerizable oligomer, a primary photoinitiator, and a monomer scavenger, wherein photopolymerization of the at least one bi-active monomer by the primary photoinitiator activates the monomer scavenger, reducing residual monomer content in a cured adhesive formed by the photopolymerization of the bi-active monomer in comparison to an otherwise identical comparative UV adhesive lacking the monomer scavenger. A method for curing the UV light curable adhesive is disclosed, including applying the UV light curable adhesive to a surface and exposing the UV light curable adhesive to UV light, free from heating the UV light curable adhesive other than any autogenous increases in temperature from exothermic polymerization reactions. A device with the UV light cured adhesive is disclosed, including the UV light cured adhesive joining a first surface to a second surface.
Dissolvable unit dose film constructs are made by providing a muco-adhesive composition including a muco-adhesive polymer matrix in which the muco-adhesive polymer matrix has a water-soluble polymer, water-dispersible polymer, water-swellable polymer, or combinations thereof and a liquid carrier. The method further includes drying the muco-adhesive composition to remove at least a portion of the liquid carrier, forming a muco-adhesive film substrate, forming a composition for an active layer, the composition including a polymer matrix in which the polymer matrix for the active layer composition includes a water-soluble polymer, water-dispersible polymer, water-swellable polymer, or combinations thereof, an active ingredient and a liquid carrier. The method further includes depositing the composition for the active layer onto the muco-adhesive substrate as a plurality of individual volumes and removing the liquid carrier from the plurality of deposited individual volumes to form a plurality of dissolvable film active layers on the muco-adhesive substrate.
Disclosed herein is a self-supporting, dissolvable, film containing dexmedetomidine or a pharmaceutically acceptable salt thereof. The film is administered orally to treat various conditions, particularly agitation, by transmucosal delivery of the active agent.
Dissolvable unit dose film constructs are made by providing a muco-adhesive composition including a muco-adhesive polymer matrix in which the muco-adhesive polymer matrix has a water-soluble polymer, water-dispersible polymer, water-swellable polymer, or combinations thereof and a liquid carrier. The method further includes drying the muco-adhesive composition to remove at least a portion of the liquid carrier, forming a muco-adhesive film substrate, forming a composition for an active layer, the composition including a polymer matrix in which the polymer matrix for the active layer composition includes a water-soluble polymer, water-dispersible polymer, water-swellable polymer, or combinations thereof, an active ingredient and a liquid carrier. The method further includes depositing the composition for the active layer onto the muco-adhesive substrate as a plurality of individual volumes and removing the liquid carrier from the plurality of deposited individual volumes to form a plurality of dissolvable film active layers on the muco-adhesive substrate.
A method of forming a kit containing multiple dissolvable unit dose constructs includes providing at least one muco-adhesive composition comprising a polymer matrix, the polymer matrix comprising a water soluble polymer, an active ingredient and a liquid carrier; forming a plurality of dissolvable thin film unit dose constructs by depositing the at least one composition onto a substrate wherein at least two adjacent dissolvable thin film unit dose constructs are formed having a pre-determined different identifiable physical characteristic with respect to the other as a result of the depositing; and packaging the plurality of dissolvable thin films in a single package to form a kit.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer matrix that includes a water soluble polymer, active ingredient, and a liquid carrier. The composition is deposited directly, such as by stenciling, to form individual unit doses without the need to cut and convert long, continuous rolls of film.
Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer matrix that includes a water soluble polymer, active ingredient, and a liquid carrier. The composition is deposited directly, such as by stenciling, to form individual unit doses without the need to cut and convert long, continuous rolls of film.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
A method of forming a liquid formulation includes preparing a mixture and adding a second component to the mixture to form the liquid formulation. The mixture includes water, a film- forming polymer, a buffer, and a first component. The first component is an active ingredient including buprenorphine or a sweetener. The second component is the active ingredient comprising buprenorphine or the sweetener. Adding the second component is the last step in creating the liquid formulation. If the first component is the active ingredient, the second component is the sweetener. If the first component is the sweetener, the second component is the active ingredient. A method of forming a water-disintegrable film includes casting a formulation film from the liquid formulation and drying the formulation film to form the water-disintegrable film. A film formulation and a water-disintegrable film are also disclosed.
A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
Adhesives are disclosed which include a methacrylate copolymer, wherein the methacrylate copolymer includes at least one methacrylate monomer component and at least one acrylic or silicone monomer component, and wherein the adhesive are gamma resistant. The adhesives may include about 45% to about 49% by weight acrylic or silicone monomer component, about 45% to about 49% by weight methacrylate monomer component, and about 2% to about 10% by weight acrylic acid or 2-hydroxyethyl acrylate. The adhesives may further include at least one additive selected from the group consisting of a plasticizer, a tackifier, a cross-linking agent, an antioxidant and combinations thereof. The adhesives may be a pressure-sensitive and low trauma adhesive. Also disclosed are medical devices including the adhesives.
C09J 133/10 - Homopolymères ou copolymères d'esters de l'acide méthacrylique
A61L 2/00 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet
Hydrophilic adhesive compositions are disclosed that contain a surfactant that is miscible, but not fully soluble in the polymer matrix of the adhesive. This permits the surfactant to continuously replenish at the surface of the adhesive as other surfactant is removed, such as when it is carried away by an aqueous sample flowing over that surface in an in-vitro diagnostic device, resulting in adhesive compositions that are inherently hydrophilic on their surfaces and do not rely on the bloom mechanism of known hydrophilic adhesives. This provides greater design options for in-vitro diagnostic device manufacturers, including the use of hydrophilic adhesive spacers in lieu of or in combination with hydrophilic top covers.
C09J 133/14 - Homopolymères ou copolymères d'esters d'esters contenant des atomes d'halogène, d'azote, de soufre ou d'oxygène en plus de l'oxygène du radical carboxyle
C08F 220/26 - Esters contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle
26.
Hydrophilic adhesives and tapes and devices containing the same
Hydrophilic adhesive compositions are disclosed that contain a surfactant that is miscible, but not fully soluble in the polymer matrix of the adhesive. This permits the surfactant to continuously replenish at the surface of the adhesive as other surfactant is removed, such as when it is carried away by an aqueous sample flowing over that surface in an in-vitro diagnostic device, resulting in adhesive compositions that are inherently hydrophilic on their surfaces and do not rely on the bloom mechanism of known hydrophilic adhesives. This provides greater design options for in-vitro diagnostic device manufacturers, including the use of hydrophilic adhesive spacers in lieu of or in combination with hydrophilic top covers.
C09J 133/14 - Homopolymères ou copolymères d'esters d'esters contenant des atomes d'halogène, d'azote, de soufre ou d'oxygène en plus de l'oxygène du radical carboxyle
C09J 133/06 - Homopolymères ou copolymères d'esters d'esters ne contenant que du carbone, de l'hydrogène et de l'oxygène, l'atome d'oxygène faisant uniquement partie du radical carboxyle
Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer matrix that includes a water soluble polymer, active ingredient, and a liquid carrier. The composition is deposited directly, such as by stenciling, to form individual unit doses without the need to cut and convert long, continuous rolls of film.
Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer matrix that includes a water soluble polymer, active ingredient, and a liquid carrier. The composition is deposited directly, such as by stenciling, to form individual unit doses without the need to cut and convert long, continuous rolls of film.
An actinic radiation activated, thermally curable solid film adhesive is disclosed that includes a film forming polymeric binder, a cationically curable resin, and a cationic photoinitiator. The solid film adhesive is capable of being processed at temperatures up to 120°C prior to exposure to actinic radiation without curing, has a latency period at room temperature following activation of the initiator, and is curable at temperatures above 50°C following activation of the initiator.
An actinic radiation activated, thermally curable solid film adhesive is disclosed that includes a film forming polymeric binder, a cationically curable resin, and a cationic photoinitiator. The solid film adhesive is capable of being processed at temperatures up to 120° C. prior to exposure to actinic radiation without curing, has a latency period at room temperature following activation of the initiator, and is curable at temperatures above 50° C. following activation of the initiator.
C09J 167/00 - Adhésifs à base de polyesters obtenus par des réactions créant une liaison ester carboxylique dans la chaîne principaleAdhésifs à base de dérivés de tels polymères
C09J 163/00 - Adhésifs à base de résines époxyAdhésifs à base de dérivés des résines époxy
C08G 59/68 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les catalyseurs utilisés
A charge collection tape includes a foil substrate and an adhesive layer laminated on the foil substrate. The foil substrate is constructed of an aluminum base foil having a conductive metal coating overlying and in direct contact with a non-oxidized surface of the aluminum base foil.
A charge collection tape is disclosed that includes a foil substrate and an adhesive layer laminated on the foil substrate. The foil substrate is constructed of an aluminum base foil having a conductive metal coating overlying and in direct contact with a non-oxidized surface of the aluminum base foil. A method of making the charge collection tape is also disclosed.
H01B 1/02 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisésEmploi de matériaux spécifiés comme conducteurs composés principalement de métaux ou d'alliages
A reactive pressure sensitive adhesive composition is disclosed. A tape formed using the reactive pressure sensitive adhesive is also disclosed. In its cured state, the pressure sensitive adhesive shows superior mechanical and electrical properties compared to conventional, non-curable charge collection tapes. The tape has a cure profile pre-selected to correspond to that of a photovoltaic cell fabrication process, such that curing can take place during cell fabrication and may occur simultaneously with one or more other curing steps employed in cell fabrication.
The invention provides disintegratable films containing a mixture of high molecular weight and low molecular weight water soluble components; and a pharmaceutically or cosmetically active ingredient. Optionally, the films contain a starch component, a glucose component, a filler, a plasticizer and/or humectant. The films are preferably in the form of a mucoadhesive monolayer having a thickness sufficient to rapidly disintegrate in the oral environment and release the active ingredient without undue discomfort to the oral mucosa. The monolayer can be cut to any desired size or shape to provide conveniently useable unit dosage forms for administration to oral or other mucosal surfaces for human pharmaceutical, cosmetic, or veterinary applications. The invention further provides methods of administering the film compositions by placing the composition into, for example, the oral cavity for a sufficient period of time to permit the film to disintegrate and release the active ingredient.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
A tape is disclosed. The tape includes a metallic foil, an adhesive layer laminated on one surface of the metallic foil and a protective polymeric coating laminated on an opposing second surface of the metallic foil. The protective coating comprises an anti-corrosion agent. The protective coating shields the metallic foil from corrosion and other drawbacks that can occur by environmental exposure. The tape readily can be employed as a busbar tape in photovoltaic cells to provide a cost-effective substitute for the tin-coated copper currently used there.
Pressure sensitive adhesives for use primarily in medical applications are disclosed. The pressure sensitive adhesives are urethane elastomeric adhesives that include a polyurethane polymer and a compatible tackifier and/or compatible plasticizer to achieve an adhesive having a predetermined compliance. The result is a pressure sensitive adhesive for application to skin that can eventually be removed with very little trauma to the skin and with a low pain rating, but which still exhibits very good peel strength when used to construct an article in which the adhesive is adhered to human skin.
The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith.
A reactive pressure sensitive adhesive composition is disclosed. A tape formed using the reactive pressure sensitive adhesive is also disclosed. In its cured state, the pressure sensitive adhesive shows superior mechanical and electrical properties compared to conventional, non-curable charge collection tapes. The tape has a cure profile pre-selected to correspond to that of a photovoltaic cell fabrication process, such that curing can take place during cell fabrication and may occur simultaneously with one or more other curing steps employed in cell fabrication.
An adhesive formulation is disclosed that includes (a) a pre-polymerized cross-linkable non-water soluble acrylic based pressure sensitive adhesive, (b) a cross-linking agent selected from the group consisting of metal chelates, silanes, epoxy-functional compounds, aziridine compounds, multifunctional amines, alkyl halide compounds, multifunctional acids, multifunctional mercaptans, multifunctional epoxy compounds, polyols in the presence of a catalyst, and combinations thereof and (c) a polyol having a weight average molecular weight in the range from 1,000 g/mol to 10,000 g/mol. When cured, the adhesive formulation is self- wetting and has a peel strength less than 20 oz/in.
C09J 133/00 - Adhésifs à base d'homopolymères ou de copolymères de composés possédant un ou plusieurs radicaux aliphatiques non saturés, chacun ne contenant qu'une seule liaison double carbone-carbone et l'un au moins étant terminé par un seul radical carboxyle, ou ses sels, anhydrides, esters, amides, imides ou nitrilesAdhésifs à base de dérivés de tels polymères
40.
Acrylic based pressure sensitive adhesive formulation
An adhesive formulation is disclosed that includes (a) a pre-polymerized cross-linkable non-water soluble acrylic based pressure sensitive adhesive, (b) a cross-linking agent selected from the group consisting of metal chelates, silanes, epoxy-functional compounds, aziridine compounds, multifunctional amines, alkyl halide compounds, multifunctional acids, multifunctional mercaptans, multifunctional epoxy compounds, polyols in the presence of a catalyst, and combinations thereof and (c) a polyol having a weight average molecular weight in the range from 1,000 g/mol to 10,000 g/mol. When cured, the adhesive formulation is self-wetting and has a peel strength less than 20 oz/in.
The invention provides disintegra table adhesive films containing a mixture of high molecular weight and low molecular weight water soluble components; and a pharmaceutically or cosmetically active ingredient. Optionally, the films contain a starch component, a polysaccharide component, a filler, a plasticizer and/or humectant. The films are preferably in the form of an adhesive layer having a thickness sufficient to disintegrate, when exposed to a moist environment and/or a trigger compound, and release the active ingredient. The films can be cut to any desired size or shape to provide conveniently useable unit dosage forms for administration to wet or moist body surfaces for human, pharmaceutical, cosmetic, or veterinary applications. The invention further provides various end uses and methods of administering the film compositions.
A pressure sensitive adhesive includes a substantially continuous polymer phase having pressure sensitive adhesive properties, and a plurality of pores arranged within the substantially continuous polymer phase and disposed to permit fluid to pass from a first side through at least a portion of the plurality of pores to a second side. The plurality of pores is substantially resistant to cold flow. A method of forming a porous pressure sensitive adhesive tape includes providing a solution for forming an adhesive having pressure sensitive adhesive properties, the solution including a pore forming material, casting a film comprising the solution, laminating a liner on the film, and exposing the adhesive to an energy source to form pores in the adhesive and cure the adhesive to form the pressure sensitive adhesive tape.
The invention provides disintegratable film compositions for diagnostic test devices. The films are prepared with a combination of components that yield films of sufficient film strength and desired disintegration profiles. A disintegratable film according to the present invention contains a water soluble high molecular weight component, a water soluble low molecular weight component, and one or more reagents for use in a diagnostic device. Optionally, the films further contain a starch component, a glucose component, a plasticizer and/or a humectant, and/or a filler. The invention further provides a diagnostic testing device, which includes a film according to an embodiment of the invention, and methods of using such devices.
The invention provides disintegratable adhesive films containing a mixture of high molecular weight and low molecular weight water soluble components; and a pharmaceutically or cosmetically active ingredient. Optionally, the films contain a starch component, a polysaccharide component, a filler, a plasticizer and/or humectant. The films are preferably in the form of an adhesive layer having a thickness sufficient to disintegrate, when exposed to a moist environment and/or a trigger compound, and release the active ingredient. The films can be cut to any desired size or shape to provide conveniently useable unit dosage forms for administration to wet or moist body surfaces for human, pharmaceutical, cosmetic, or veterinary applications. The invention further provides various end uses and methods of administering the film compositions.
A61L 15/64 - Utilisation de matériaux caractérisés par leur fonction ou leurs propriétés physiques spécialement adaptés pour être résorbables à l'intérieur du corps
A61Q 19/00 - Préparations pour les soins de la peau
05 - Produits pharmaceutiques, vétérinaires et hygièniques
17 - Produits en caoutchouc ou en matières plastiques; matières à calfeutrer et à isoler
Produits et services
Medical adhesive tape, high performance adhesives, custom coated and dissolvable films, laminates and pressure sensitive adhesive products. Adhesive tapes and adhesive films, not for stationery use or medical purposes.
17 - Produits en caoutchouc ou en matières plastiques; matières à calfeutrer et à isoler
Produits et services
Adhesives and adhesive coated materials for household, stationery, packaging and wrapping purposes; adhesive tape, adhesive films, adhesive foils, adhesive strips, adhesive sheets, adhesive foam tape, adhesive foam strips, and transfer adhesives, all being for stationery use. Adhesive coated materials other than for stationery, household or medical purposes; adhesive tape, adhesive films, adhesive foils, adhesive strips, adhesive sheets, adhesive foam tape, adhesive foam strips and transfer adhesives, not being for stationery or medical purposes; protective masking sheeting utilizing pressure sensitive adhesives; pressure sensitive foam tape and custom laminating sheeting utilizing pressure sensitive adhesives; pressure sensitive adhesives tapes, coated films, and laminates, all being for use in the industry.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
17 - Produits en caoutchouc ou en matières plastiques; matières à calfeutrer et à isoler
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Adhesive bands, tapes, and plasters for medical purposes; cement, adhesives, lacquers, mastics, abrasives, and impression materials for medical and dental purposes. Adhesive bands and adhesive tapes not for medical, household or stationery purposes, caulking materials; plastic films; insulating tapes and bands; materials for filling, stopping, packing and repairing leaks. Design and manufacture of high performance adhesives, custom coated and dissolvable films, laminates and pressure sensitive adhesive products; research, development, engineering and design services in the field of adhesives.
17 - Produits en caoutchouc ou en matières plastiques; matières à calfeutrer et à isoler
Produits et services
Non-metal protective masking sheeting for use in the manufacture of rigid plastic and metal panels; pressure sensitive adhesive closed cell foam used for bonding and assembly; adhesive tape for bonding and splicing; custom laminating non-metal sheeting for bonding and assembly; pressure sensitive adhesives, specialty pressure sensitive adhesive tapes, and coated non-metal adhesive coated plastic films for bonding and assembly; laminates consisting primarily of plastic with or without a metal layer for application to a substrate
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Custom manufacture for others in the field of high performance adhesives, custom coated and dissolvable films, laminates and pressure sensitive adhesive products Design for others in the field of high performance adhesives, custom coated and dissolvable films, laminates and pressure sensitive adhesives
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Custom manufacture of pressure sensitive adhesive systems, laminates and coated films to order and specification Research, development, engineering and design services in the field of pressure sensitive adhesive systems, laminates and coated films
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
17 - Produits en caoutchouc ou en matières plastiques; matières à calfeutrer et à isoler
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical products for use in industry; adhesives. Adhesive bands, tapes, and plasters for medical purposes; cement, adhesives, lacquers, mastics, abrasives, and impression materials for medical and dental purposes. Adhesive bands and adhesive tapes not for medical, household or stationery purposes, caulking materials; plastic films; insulating tapes and bands; materials for filling, stopping, packing and repairing leaks. Research, development, engineering and design services in the field of adhesives.
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Custom manufacture of pressure sensitive adhesive systems to order and specification; research, development, engineering and design services in the field of pressure sensitive adhesive systems.
37 - Services de construction; extraction minière; installation et réparation
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
custom manufacture of pressure sensitive adhesive systems to order and specification research, development, engineering and design services in the field of pressure sensitive adhesive systems
