CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
Camarena Femenía, Francisco
Jiménez González, Noé
Benlloch Baviera, José María
García Garrigós, Juan José
Rodríguez García, Juan José
Alonso Ramos, José Luís
Limens Pinaque, Jesús
Rodríguez Sendra, Josep
Arándiga Martínez, Adrián Luís
Abrégé
The invention relates to an apparatus for ultrasound treatment which allows an ultrasound treatment with preselected targets to be carried out with submillimetric accuracy. The apparatus eliminates the mechanical coupling problems between the emitter and the animal, facilitating the positioning of the ultrasonic bulb using a laser spot that is coaxial to the ultrasonic beam, or of an optical vision system, which guides the system over the tissue surface.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Fernández Saavedra, Roemi Emilia
Navas Merlo, Eduardo
Rodríguez Nieto, Daniel
Ojeda Velázquez, Marta
Abrégé
The present invention relates to a mobile two-arm robotic system for performing grafts on plants comprising a navigation system (2), a perception system (3), a central control module (9) and a two-arm robotic handler (4) comprising a first arm with a parallel clamp (5) comprising two gripping fingers (15), a second arm with a multipurpose clamp (6) comprising cutter fingers with a blade (17) to perform cuts on the plants (12, 13) and a press area (19), to handle a graft clip (14) intended to be positioned on the cut plants (12, 13).
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Lagarón Cabello, José María
Prieto López, Cristina
Roig Sánchez, Soledad
Marcoaldi, Chiara
Carrasco Muñoz, Antonio Jesús
Abrégé
The present invention relates to the preparation and application of a coating of 60 g/m2 or less comprising a polymer and an additive, produced by means of electrohydrodynamic, aerohydrodynamic processing or any combination thereof. The coating is recyclable and/or biodegradable and/or compostable and can be applied on any type of virgin biobased substrate or with one or more coatings. The coating of the invention serves to provide the biobased substrate on which it is applied with barrier properties against gases, vapours and liquids, in addition to allowing the assembly to be heat-sealed and/or heat-formed. This invention can be used to produce packaging materials, among other uses.
D21H 19/34 - Couches sans pigments appliquées sous une forme autre que la solution aqueuse définie dans le groupe comprenant de la cellulose ou ses dérivés
D21H 27/38 - Papier particulier non prévu ailleurs, p. ex. obtenu par des procédés multi-étapes à plusieurs jets au moins une des feuilles ayant une composition fibreuse différente de celle des autres feuilles
B65D 65/40 - Emploi de stratifiés pour des buts particuliers d'emballage
B65D 65/46 - Emploi de matériaux désintégrables, solubles ou comestibles
B05D 1/00 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces
B05D 1/04 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces réalisés par pulvérisation comportant l'emploi d'un champ électrostatique
C08L 67/07 - Polyesters non saturés comportant des liaisons non saturées carbone-carbone terminales
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Bañares Gonzalez, Miguel Angel
Serrano Lotina, Ana Maria
Llanos Fernandez-Valmayor, Paula
Gómez López, Alicia
Alcamí Peretjo, Antonio
Vazquez Calvo, Angela
Abrégé
The present invention relates to a catalytic material with oxidant and/or acid-base properties, the preparation method thereof and the specific use thereof for pathogen inactivation. The invention also relates to a filter comprising the material.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
ONECHAIN IMMUNOTHERAPEUTICS SL (Espagne)
Inventeur(s)
García León, María Jesús
Fuentes Villarejo, Patricia
Alcain Sánchez, Juan
Toribio García, María Luisa
García Pérez, Laura
Díaz Cortés, Víctor Manuel
Abrégé
The present invention refers to a novel and efficient method for large-scale selective generation of yδ T cells, preferably human Vδ1+yδ T cells, optimal for clinical application in adoptive immunotherapy of cancer. In this sense, considering that both human cord blood HPCs, currently elected as source of stem cells in the clinic, and human early thymic progenitors can efficiently generate de novo human yδ T cells in response to Notch signalling, and most efficiently in response to the Notch ligand Jag2, the method thus comprises inducing the differentiation of cord blood CD34+ hematopoietic progenitor cells (HPCs) and/or human CD34+ early thymic progenitors, by activating them with Jag2 Notch ligands.
C12N 5/0783 - Cellules TCellules NKProgéniteurs de cellules T ou NK
A61K 40/11 - Lymphocytes T, p. ex. lymphocytes infiltrant les tumeurs [TIL] ou lymphocytes T régulateurs [Treg]Cellules tueuses activées par les lymphokines [LAK]
FUNDACIÓ INSTITUT CATALÀ DE NANOCIÈNCIA I NANOTECNOLOGIA (ICN2) (Espagne)
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Lira-Cantú, Mónica
Zambrzycki, Marcel
Karimipour, Masoud
Abrégé
The present application relates to a carbon paste composition and a method of producing the same. The carbon paste composition comprises polyvinylcarbazole (PVK) and a tailored mixture of solvents. The PVK is used as a semiconducting binder replacing the conventionally used poly(vinyl acetate) found in commercial carbon-based pastes. This carbon paste composition is suitable for use in the preparation of perovskite solar cells or other types of organic electronics. This application also discloses a method to deposit the carbon paste composition in a perovskite solar cell.
H01B 1/24 - Matériau conducteur dispersé dans un matériau organique non conducteur le matériau conducteur comportant des compositions à base de carbone-silicium, du carbone ou du silicium
H10K 71/15 - Dépôt d'une matière active organique en utilisant un dépôt liquide, p. ex. revêtement par centrifugation caractérisé par le solvant utilisé
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Ramos, Tomás
Porras, Diego
Gomez, Alvaro
García Ripol, Juan José
González Tudela, Alejandro
Abrégé
Method for stabilizing a non-linear parametric amplifier array comprising N non-linear resonator modes, linear and non-linear couplings between sites, external coherent control fields on each site and input/output ports to send and retrieve an amplified signal; the method comprising: setting the phases of the external coherent control fields to grow linearly with site index, dividing the N sites of the array in 3 regions, setting, in the central region, an homogeneous steady-state solution, assuming periodic boundary conditions, and setting the central quantities to produce directional topological amplification in an homogeneous system; in the left and right buffer regions, imposing to some quantities a smoothly increasing or decreasing profile function from the boundaries to the center; choosing external coherent control frequencies or bare resonator frequencies to locally compensate for the photon number-dependent frequency shifts induced by non-linearities; and solving the exact steady-state mean-field displacements assuming open boundary conditions.
H03F 5/00 - Amplificateurs comportant comme éléments d'amplification à la fois des tubes à décharge et des dispositifs à semi-conducteurs
H03F 19/00 - Amplificateurs utilisant les effets de supraconductivité
H03F 7/04 - Amplificateurs paramétriques utilisant un élément à capacité variableAmplificateurs paramétriques utilisant un élément à permittivité variable
8.
REDOX FLOW BATTERIES HAVING ELECTROLYTE DISTRIBUTORS WITH INTEGRATED CHANNELS AND METHOD OF MANUFACTURE THEREOF
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
FUNDACIÓN AGENCIA ARAGONESA PARA LA INVESTIGACIÓN Y EL DESARROLLO (ARAID) (Espagne)
Inventeur(s)
Barreras Toledo, Félix
Ortiz De Landazuri Suárez, Ignacio
Barranco Riveros, José Enrique
Montiel Argaiz, Manuel
Abrégé
The present invention discloses a battery formed by at least one cell or cell stack incorporating flow distributors (1) that house the electrodes (3), polymer membranes (5), bipolar plates (4) and current collector plates (7) that are embedded in a resin block (10) that ensures sealing tightness. The present invention further discloses a method for manufacturing said battery.
H01M 8/18 - Éléments à combustible à régénération, p. ex. batteries à flux REDOX ou éléments à combustible secondaires
H01M 8/2455 - Groupement d'éléments à combustible, p. ex. empilement d'éléments à combustible avec des réactifs liquides, solides ou chargés en électrolyte
9.
PROTEOLYTIC CHIMERAS FOR THE TREATMENT OF A CANCER RELATED TO CERT
CONSEJO SUPERIOR DE INVESTIGACIONESCIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT DE BARCELONA (Espagne)
Inventeur(s)
Casas Brugulat, Josefina
Bujons Vilas, Jordi
Fabriàs Domingo, Gemma
Crosas Navarro, Bernat
Abad Saiz, Jose Luis
Abrégé
USP14 inhibitors of formula (I), wherein the meanings for the various substituents are as disclosed in the description, for use as a medicament and, particularly for the treatment of a cancer related to CERT.
C07D 401/14 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant au moins trois hétérocycles
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
10.
METHOD AND DEVICE FOR PROCESSING THREE-DIMENSIONAL IMAGES THAT ALLOWS DISTORTIONS TO BE MINIMISED
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT DE VALÈNCIA (ESTUDI GENERAL) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
EMPRESA NACIONAL DE RESIDUOS RADIOACTIVOS, S.A. (Espagne)
Inventeur(s)
Albiol Colomer, Francisco Javier
Caballero Ontanaya, Luis
Tortajada Velert, Salvador
Burriel Navarro, Helena
Albiol Colomer, Alberto
Abrégé
The present invention relates to a method and device for processing three-dimensional images that allows distortions to be minimised in a sensor measuring the direction of a signal from a source and that comprises the steps of: providing one or more measuring sensors for measuring a signal coming from a source, the sensors being associated with one or more spatial positions, wherein the measuring sensors are configured to obtain a direction of the measured signal with respect to said spatial positions; breaking down the sensor into one or more locations; generating one or more geodesic spheres in each location, wherein each geodesic sphere comprises a set of triangular elements with vertices that are almost evenly spaced apart; encoding a signal representative of the direction between the centre of the sphere and the position of the source in a set of vertices of the sphere; and generating a vector associated with each vertex, to store information about the signal intensity.
G06T 3/08 - Projection d’images sur des surfaces non planes, p. ex. sur des écrans géodésiques
H01Q 3/26 - Dispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la phase relative ou l’amplitude relative et l’énergie d’excitation entre plusieurs éléments rayonnants actifsDispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne faisant varier la distribution de l’énergie à travers une ouverture rayonnante
G06V 10/58 - Extraction de caractéristiques d’images ou de vidéos relative aux données hyperspectrales
G06F 16/787 - Recherche de données caractérisée par l’utilisation de métadonnées, p. ex. de métadonnées ne provenant pas du contenu ou de métadonnées générées manuellement utilisant des informations géographiques ou spatiales, p. ex. la localisation
G06T 7/55 - Récupération de la profondeur ou de la forme à partir de plusieurs images
11.
METHOD FOR RECOVERING LITHIUM FROM ELECTROLYTES OF LITHIUM-ION BATTERIES
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
López Gómez, Félix Antonio
Alcaraz Romo, Lorena
Rodríguez Largo, Olga
Abrégé
The present invention belongs to the field of recovering lithium salts from used batteries, and more specifically, to a method for recovering the degradation products from a liquid electrolyte formed by at least one lithium salt from the black mass of used lithium batteries. The method comprises the steps of hydrolysis, filtering, evaporating, and optionally, thermal processing and subsequent selective dissolution, to thus obtain lithium salts from the electrolyte recovered from the used lithium battery. This method is capable of recovering lithium salts in a simple manner, and without the use of high temperatures or chemical reagents.
H01M 10/54 - Récupération des parties utiles des accumulateurs usagés
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
12.
CO2 CAPTURE METHOD USING A COUNTERCURRENT MOVING BED REACTOR
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Abanades Garcia, Juan Carlos
Alvarez Criado, Yolanda
Abrégé
This invention discloses a method to capture CO2 from a gas using Ca-containing porous solids composed of Ca(OH)2 and/or CaO, arranged in a packed bed to contact with the gas. The method is characterized by the use of a carbonator reactor operated in a countercurrent moving bed mode. Such configuration provides the conditions to generate an autothermal central region in the reactor at optimum carbonation temperature between 600-700° C. when using Ca-containing stones, pellets or extruded bricks with effective diameters or thickness between 1-10 cm and solid residence times between 1 to 20 hours, when treating gases with CO2 content between 2-25% v. In another embodiment, the method provides optimum conditions for efficient CO2 capture from gases with CO2 content below 2% v, including ambient air, at temperatures below 100° C. and relative humidity between 80-100%, to achieve maximum carbonation conversion with solid residence times between 20 to 200 hours.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Parrilla Romero, Montserrat
Aparicio Secanellas, Sofía
González Hernández, Margarita
Martínez Graullera, Oscar
Ibáñez Rodríguez, Alberto
Anaya Velayos, José Javier
Gauna León, Iñaki
Acebes Pascual, Mª Montserrat
De Matías Jiménez, Héctor
Álvarez De Pablos, Alberto
Abrégé
The present invention relates to a method of non-destructive evaluation using ultrasound reverberated signals to determine the structural integrity of a part and comprising: simulating an acoustic propagation of an emitted ultrasound pulse by iteratively varying an angle of incidence, a signal reception gain and an acquisition time; determining those which allow a reverberated signal to be generated and detected inside the part; obtaining a signal reverberated inside the part; applying to the obtained reverberated signal a deep neural network trained by means of a set of ultrasound signals obtained from flawless reference parts and configured to determine a synthetic reverberated signal that better matches the reverberated signal obtained; and determining a reconstruction error value, a distance metric between the obtained reverberated signal and the synthetic reverberated signal; and determining the presence of flaws in the part based on said reconstruction error value.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
Prieto González, Gonzalo
Ceteroni, Ilaria
Aldegheri, Fausto
Abrégé
The present invention relates to a method for producing N-substituted alkylamides, including N-substituted fatty alkylamides, by placing a synthesis gas and an amide compound in contact with a ruthenium catalyst.
C07C 231/08 - Préparation d'amides d'acides carboxyliques à partir d'amides par réaction sur les atomes d'azote de groupes carboxamide
C07C 233/01 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques
C07C 233/05 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués avec des atomes de carbone de groupes carboxamide liés à des atomes de carbone d'un squelette carboné saturé acyclique ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques
C07C 233/06 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués avec des atomes de carbone de groupes carboxamide liés à des atomes de carbone d'un squelette carboné saturé acyclique ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone d'un cycle autre qu'un cycle aromatique à six chaînons
C07C 233/07 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone acycliques ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués avec des atomes de carbone de groupes carboxamide liés à des atomes de carbone d'un squelette carboné saturé acyclique ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone d'un cycle aromatique à six chaînons
C07C 1/04 - Préparation d'hydrocarbures à partir d'un ou plusieurs composés, aucun d'eux n'étant un hydrocarbure à partir d'oxydes de carbone à partir de monoxyde de carbone avec de l'hydrogène
B01J 23/46 - Ruthénium, rhodium, osmium ou iridium
C07C 45/49 - Préparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogènePréparation des chélates de ces composés par réaction avec le monoxyde de carbone
B01J 23/46 - Ruthénium, rhodium, osmium ou iridium
B01J 31/16 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des complexes de coordination
16.
MACHINE LEARNING METHOD FOR PROCESSING FORCEDISTANCE CURVES IN FORCE MICROSCOPY
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
García García, Ricardo
Tejedor Reyes, Jaime
Abrégé
The present invention relates to a method for processing force versus distance curves obtained by means of a force microscope by applying a supervised machine learning method based on functional multilayer perceptron neural networks. The method allows for rapid processing of thousands of experimental curves and eliminates errors associated with the nonlinearity of the AFM tip displacement signal. This step allows the accurate prediction of various mechanical and nanomechanical properties such as Young's modulus, compressive modulus or fluidity coefficient. Likewise, the method of the invention 0 facilitates the measurement of nanomechanical properties of materials in real time.
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
17.
MULTILAYER-BASED COSMETIC PRODUCTS, METHOD OF PRODUCTION AND USE THEREOF
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Lagaron Cabello, Jose Maria
Prieto Lopez, Cristina
Evtoski, Zoran
Teno Díaz, Jorge
Talón Argente, Emmanuelle
Escriche Bea, Úrsula
Abrégé
The present invention falls within the area of polymeric materials based on ultrafine fibres applied to the cosmetics sector, and relates to the production method of same and the use thereof for the production of solid products with high cosmetic efficiency in multilayer format manufactured using an electro-hydrodynamic processing technique, an aero-hydrodynamic processing technique or any combination of the two.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Guasch Camell, Judit
Ratera Bastardas, Imma
Veciana Miró, Jaume
Santos Abreu, Roberto Fabião
Pérez Del Río, Eduardo
Castellote Borrell, Miquel
Abrégé
The present invention relates to an inverse opal (IOPAL) hydrogel formed with poly(ethylene)glycol (PEG) covalently bonded to heparin (Hep). The invention also relates to the use of said hydrogel as well as to the procedure, based in the inverted colloidal crystal technique, for preparing the same. Said hydrogel has demonstrated to be very effective and useful in cell culture and more particularly in immunotherapy and in organoid culture.
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
Alonso Otamendi, Joseba
Galve Conde, Fernando
Algarín Guisado, José Miguel
Benlloch Baviera, José María
Webb, Andrew
Abrégé
The present invention relates to a method of classification of magnetic resonance, MR, signals indicative of one or more portions of a subject or a sample (10) of diagnostic or prognostic interest, realized by means of an NMR scanner (9) and a processing means. The method comprises acquiring, with the NMR scanner (9), a set of MR signal data (2, 2') for each one or more MR signals emitted from the subject or the sample (10). The one or more acquired MR signal data sets (2, 2') consist of one-dimensional time-domain signal data and are processed by the processing means. The processing means classifies the one or more MR signals in one or more diagnostic or prognostic interest groups associated to reference data. The reference data comprise one-dimensional time-domain signal data. The present invention also relates to a system and a computer program adapted for carrying out said method.
G01R 33/56 - Amélioration ou correction de l'image, p. ex. par des techniques de soustraction ou d'établissement de moyenne
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
Fluorescent Aggregates of Poly(Cyclohexylene Dimethylene Terephthalate), Method for Obtaining Same, and Use Thereof as a Physically Unclonable Label for Identifying and/or Tracing Packaging for Cosmetic and/or Perfume Products
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
INENTIA ARÔ, S.L. (Espagne)
Inventeur(s)
López Manchado, Miguel Ángel
Verdejo Márquez, Raquel
Hoyos Núñez, Mario
Andrinal López, Daniel
Cisneros De Los Arcos, Ramón Ignacio
Fernández Benito, Amparo
Abrégé
Spherical aggregates of semi-crystalline thermoplastic polyester, poly(cyclohexylene dimethylene terephthalate), with a size distribution of between 160 nm and 200 nm fluorescence in the visible spectrum and are deposited on a thermoplastic aromatic polyester substrate or a thermoplastic polyolefin. The aggregates may be used as a physically unclonable label, for identifying and/or tracing packaging for cosmetic products and/or perfumes. Therefore, the aggregates provide a benefit within the field of anti-counterfeit packaging, particularly in the area of anti-counterfeit packaging for cosmetic and/or perfume products.
FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA (Espagne)
UNIVERSITAT ROVIRA I VIRGILI (Espagne)
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Lleonart Pajarín, Matilde Esther
Pujadas Anguiano, Gerard
García Vallvé, Santiago
García Mayea, Yoelsis
Sánchez García, Almudena
Gimeno Vives, Aleix
Mestres Truyol, Júlia
Llebaria Soldevilla, Amadeo
Serra Comas, Maria Del Carmen
Catena Ruiz, Juan Lorenzo
Josa Culleré, Laia
Abrégé
It relates to compounds of formula (I) for use in the treatment of cancers that overexpress TSPAN1 protein. It also relates to pharmaceutical compositions comprising these compounds, and to their therapeutical indication in the treatment of different types of cancer, in particular those resistant to conventional methods of treatment.
A61K 31/423 - Oxazoles condensés avec des carbocycles
A61K 31/428 - Thiazoles condensés avec des carbocycles
A61K 31/443 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'oxygène comme hétéro-atome du cycle
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
C07D 221/00 - Composés hétérocycliques contenant des cycles à six chaînons ne comportant qu'un atome d'azote comme unique hétéro-atome du cycle, non prévus par les groupes
C07D 235/00 - Composés hétérocycliques contenant des cycles diazole-1, 3 ou diazole-1, 3 hydrogéné, condensés avec d'autres cycles
C07D 263/00 - Composés hétérocycliques contenant des cycles oxazole-1, 3 ou oxazole-1, 3 hydrogéné
C07D 263/52 - Composés hétérocycliques contenant des cycles oxazole-1, 3 ou oxazole-1, 3 hydrogéné condensés avec des carbocycles ou avec des systèmes carbocycliques
C07D 277/60 - Composés hétérocycliques contenant des cycles thiazole-1, 3 ou thiazole-1, 3 hydrogénés condensés avec des carbocycles ou avec des systèmes carbocycliques
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Metelkina, Olga
Gangluff, Meike
Agrawal, Neha
Schille, Stefan Albrecht
Moreno Herrero, Jorge
Kuriakose Thomas, Alvin
García Fernández, José Manuel
Benito Hernández, Juan Manuel
De La Cruz Ruiz, Noelia
Puerto Madorrán, María José
Abrégé
Provided herein are particles and compositions comprising one or more glycolipids and a nucleic acid, wherein the one or more glycolipids are represented by, for example, formula I: G1-G2-G3 or a pharmaceutically acceptable salt thereof.
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
C12N 15/88 - Introduction de matériel génétique étranger utilisant des procédés non prévus ailleurs, p. ex. co-transformation utilisant la micro-encapsulation, p. ex. utilisant des vésicules liposomiques
C07C 335/00 - Thiourées, c.-à-d. composés contenant l'un des groupes: les atomes d'azote ne faisant pas partie de groupes nitro ou nitroso
C07H 15/04 - Radicaux acycliques non substitués par des structures cycliques liés à un atome d'oxygène d'un radical saccharide
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Metelkina, Olga
Gangluff, Meike
Agrawal, Neha
Albrecht Schille, Stefan
Moreno Herrero, Jorge
Kuriakose Thomas, Alvin
García Fernández, José Manuel
Benito Hernández, Juan Manuel
De La Cruz Ruiz, Noelia
Puerto Madorrán, María José
Abrégé
Provided herein are particles and compositions comprising one or more glycolipids and a nucleic acid, wherein the one or more glycolipids are represented by, for example, formula I or a pharmaceutically acceptable salt thereof.
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
C12N 15/88 - Introduction de matériel génétique étranger utilisant des procédés non prévus ailleurs, p. ex. co-transformation utilisant la micro-encapsulation, p. ex. utilisant des vésicules liposomiques
C07C 335/00 - Thiourées, c.-à-d. composés contenant l'un des groupes: les atomes d'azote ne faisant pas partie de groupes nitro ou nitroso
C07H 15/04 - Radicaux acycliques non substitués par des structures cycliques liés à un atome d'oxygène d'un radical saccharide
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
Mon Conejero, Marta
Leyva Pérez, Antonio
Oliver Meseguer, Judit
Abrégé
The invention relates to a method for obtaining a linear, internal C10-C16 alkene from an unsubstituted linear, terminal C10-C16 alkene in the presence of a metal precursor. The unsubstituted linear terminal C10-C16 alkene is mixed with a supported or non-supported metal precursor. The mixture obtained is heated at a temperature of between 150° C. and 300° C., wherein the metal precursor gives rise to the in-situ formation of isolated metal atoms which act as catalysts. The metal precursor is used in an amount of less than 100 ppm by weight with respect to the unsubstituted linear terminal C10-C16 alkene. The mixing and heating are carried out in the absence of a solvent, The metal precursor is Ru.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSIDAD DE SEVILLA (Espagne)
ACADEMIA SINICA (Taïwan, Province de Chine)
Inventeur(s)
García Fernández, José Manuel
Ortiz Mellet, Carmen
González Cuesta, Manuel
Sánchez Fernández, Elena Matilde
Chang, Ya-Jen
Lai, Alan Chuan-Ying
Abrégé
The invention relates to a 5-aminohexahydro-6,7,8-trihydroxy-3H-oxazo-lo[3,4-a]pyridin-3-one (i.e. 2,3,4-trihydroxy-5N,6O-oxomethylidene-nojirimycin-1-amine) glycol-ipid mimetic derivative of formula (I) acting as antagonists or agonist of the TLR4 for the treatment and/or prevention of an immune disease such as e.g. acute inflammation, chronic disease allergy, the Metabolic Syndrome, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), immune mediated hepatitis, an autoimmune disease, graft rejection pathology, inflammatory bowel disease, atherosclerosis and airway hyperactivity, such as e.g. asthma and allergic rhinitis. An exemplary compound is e.g. example 1, compound (1).
The invention relates to a 5-aminohexahydro-6,7,8-trihydroxy-3H-oxazo-lo[3,4-a]pyridin-3-one (i.e. 2,3,4-trihydroxy-5N,6O-oxomethylidene-nojirimycin-1-amine) glycol-ipid mimetic derivative of formula (I) acting as antagonists or agonist of the TLR4 for the treatment and/or prevention of an immune disease such as e.g. acute inflammation, chronic disease allergy, the Metabolic Syndrome, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), immune mediated hepatitis, an autoimmune disease, graft rejection pathology, inflammatory bowel disease, atherosclerosis and airway hyperactivity, such as e.g. asthma and allergic rhinitis. An exemplary compound is e.g. example 1, compound (1).
A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (Espagne)
UNIVERSITAT AUTONOMA DE BARCELONA (Espagne)
Inventeur(s)
Gould, Darren
Serra Graells, Francesc
Suanes, Alejandro
Abrégé
Disclosed herein is a readout-circuit. The readout-circuit is configured for converting an analog sensor charge into a digital output count. The readout-circuit includes at least one integrate-and-fire(IAF)-circuit. The IAF-circuit is configured for converting the analog sensor charge into a first digital output count. An analog voltage remainder after a final IAF cycle is further processed. The readout-circuit includes at least one analog-to-digital-converter (ADC). The ADC is configured for converting the analog voltage remainder into a second digital output. Further, disclosed herein are a photodetector and a method for readout of an analog sensor charge.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Fundación Para La Investigación E Innovación Biosanitaria En El Principado De Asturias (Espagne)
Inventeur(s)
Rodríguez-Rodero, Sandra
Tejedor Vaquero, Juan Ramón
Fernández Fernández, Agustín
Fernández Fraga, Mario
Delgado Álvarez, Elías
Morales Sánchez, Paula
Menendez Torre, Edelmiro
Abrégé
The invention relates to an in vitro method for the diagnosis and/or prognosis of thyroid carcinoma, discriminating between benign and malignant nodules, by comparing the methylation level of the cytosine residue of various CpG sites, particularly the CpG sites at position 97,858,492-97,858,493 of the human chromosome 13, position 74,957,673-74,957,674 of the human chromosome 14 and/or position 5,672,830-5,672,831 of the human chromosome 20. Further, the present invention relates to the use of the methylation levels of said CpG sites and the kit for in vitro determination of the methylation levels.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
G16B 20/20 - Détection d’allèles ou de variantes, p. ex. détection de polymorphisme d’un seul nucléotide
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
NIPPON HOSO KYOKAI (Japon)
Inventeur(s)
Bertalmío Barate, Marcelo José
Morita, Yasuko
Abrégé
Temporal pooling method for video quality assessment, particularly high-framerate (HFR), high-dynamic range (HDR) and 8K ultra-high-definition (8K UHD) videos, with which it is possible to create a video metric from any arbitrary image metric, easily outperforming state-of-the-art video quality metrics.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Escudero Feliu, Julia
León López, Josefa
Jiménez López, José C.
Núñez Torres, María Isabel
Carazo Gallego, Ángel
Lima Cabello, María Elena
Puentes Pardo, José David
Moreno San Juan, Sara
Abrégé
The present invention relates to β-conglutin proteins of the blue lupin seed (Lupinus angustifolius L.), preferably β1, β3 and β6 isoforms, for use thereof as an adjuvant and radiosensitiser in the treatment of cancer, preferably breast cancer and more preferably, triple-negative breast cancer, with radiotherapy with ionising radiation.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Gómez Merchán, Rubén
Leñero Bardallo, Juan Antonio
Rodríguez Vázquez, Ángel
Abrégé
The invention relates to an asynchronous solar sensor, capable of calculating the relative position of the sun with respect to the centroid thereof, which comprises a very low-power pixel matrix, with N rows and M columns, with a photodiode working in a photovoltaic region in each pixel, wherein the pixels are connected in a common row line and a common column line; a pin-hole optics module, linked to the matrix, and comprising a hole through which a light passes, an illuminated region being generated on the matrix; and a processing module, connected to the common row line and to the common column line of the pixel matrix, configured directly to determine the centroid of the illuminated region.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (Espagne)
UNIVERSITAT DE VALÈNCIA (Espagne)
Inventeur(s)
Fernández-Mayoralas Álvarez, Alfonso
Revuelta Crespo, Julia
García-Junceda Redondo, Eduardo
Bastida Codina, Agatha
Geller, Ron
Francés Gómez, Clara
Latorre Roselló, Victor
Martín Acebes, Miguel Ángel
Saiz Calahorra, Juan Carlos
Gutiérrez Adán, Alfonso
Abrégé
The invention relates to sulfated chitosan derivatives of formula (I), wherein the meanings for the various substituents are as disclosed in the description, for their use in the treatment and/or prevention of a viral infection, particularly wherein the viral infection is caused by SARS-CoV-2 such as COVID-19 or RSV.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSIDAD DE SEVILLA (Espagne)
ACADEMIA SINICA (Taïwan, Province de Chine)
Inventeur(s)
García Fernández, José Manuel
Ortiz Mellet, Carmen
González Cuesta, Manuel
Herrera González, Irene
Chang, Ya-Jen
Lai, Alan Chuan-Ying
Abrégé
The invention relates to a multiantennary glycolipid mimetics of formula (I), wherein X, Y, Z and R1 are defined in the description, or a pharmaceutical composition thereof and their use as a medicament, particularly, for the treatment and/or prevention of an immune disease cursed by Th1/Th2 imbalance. Further the invention relates to a vaccine which comprises a compound of formula (I).
The invention relates to a multiantennary glycolipid mimetics of formula (I), wherein X, Y, Z and R1 are defined in the description, or a pharmaceutical composition thereof and their use as a medicament, particularly, for the treatment and/or prevention of an immune disease cursed by Th1/Th2 imbalance. Further the invention relates to a vaccine which comprises a compound of formula (I).
A61K 31/439 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle le cycle formant une partie d'un système cyclique ponté, p. ex. quinuclidine
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p. ex. par les adjuvants chimiques
33.
COMPOUNDS AND ANTIBODIES FOR THE IMMUNODETECTION OF CITRININ
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Mercader Badia, Josep Vicent
Abad Fuentes, Antonio
Abad Somovilla, Antonio
Agulló Blanes, Consuelo
Navarro Fuertes, Ismael
Ulloa Campos, Diego Alonso
Abrégé
The present invention relates to compounds, in particular conjugates and labelled derivatives of citrinin at a new position in the molecule, suitable for the production of antibodies with a high affinity for citrinin. The present invention also relates to the use of said citrinin conjugates and labelled derivatives of citrinin as test antigens. The invention also relates to the use of the compounds for the analysis, concentration and extraction of citrinin using the obtained antibodies, in sometimes together with test antigens that are conjugates or labelled derivatives. The invention also provides a kit for analysing citrinin comprising antibodies against said mycotoxin, sometimes together with test antigens that are conjugates or labelled derivatives of citrinin.
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/532 - Production de composés immunochimiques marqués
C07K 16/14 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de champignons, d'algues ou de lichens
B01D 15/38 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction spécifique non couverte par un ou plusieurs des groupes , p. ex. chromatographie d'affinité, chromatographie d'échange par ligand ou chromatographie chirale
34.
MECHANICAL RESONATOR WITH LOW LEVEL OF SYMMETRY FOR THE MEASUREMENT OF THE MASS OF INDIVIDUAL PARTICLES
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Sanz Jiménez, Adrián
Ruz Martínez, José Jaime
Gil Santos, Eduardo
Malvar Vidal, Oscar
Tamayo De Miguel, Javier
Calleja Gómez, Montserrat
Abrégé
A mechanical resonator with low level of symmetry for the measurement of the mechanical properties of individual particles includes: a resonator element made of an elastic material and adapted for sustaining at least one oscillation mode, and a clamping structure supporting the resonator element. Additionally, all edges of the resonator element are anchored to the clamping structure. The thickness of the resonator element is much smaller than its length and width, such as a membrane. Its mechanical symmetry is N≤2, and its aspect ratio comprised between 1+10*ma/M and 100. Further, ma is the mass of a particle whose mass is to be measured and M is the mass of the resonator element used to measure it.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSIDAD DE SEVILLA (Espagne)
Inventeur(s)
Lamouaraa Sedlackova, Yassine
Carmona Galán, Ricardo
Fernández Berni, Jorge
Abrégé
The present invention relates to a system and a method for capturing images with simultaneous automatic exposure (AE) and high dynamic range (HDR) in a single shot, simultaneously performing AE and HDR during the capture of an image. For each photointegration period established to produce the image, the circuitry of a pixel matrix automatically adjusts its response to a mean lighting at the time and adapts a radiation map of the scene within an available pixel signal range.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Lagaron Cabello, José María
Prieto López, Cristina
Teno Díaz, Jorge
González Ortiz, Danae
Abrégé
The present invention falls within the field of polymeric materials based on ultrafine fibres applied to the cosmetics sector, the invention relating to the method and application for manufacturing high-cosmetic-efficiency solid products in sheet format, manufactured by means of electro-hydrodynamic processing techniques, aero-hydrodynamic processing techniques, or any combination thereof.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Blanco González, María Dolores
García Ramos, Susana
Hernández Alonso, María Dolores
Sánchez Magdaleno, Raquel
Martínez Huerta, María Victoria
Francés Pérez, Victoria De Los Ángeles
Abrégé
It relates to a pyrolyzed composite catalyst, comprising electrocatalytically active metal alloy nanoparticles, and a nitrogen-doped carbonaceous matrix, wherein the matrix comprises a pyrolysis product of a polyamide material. A one-step method for preparing a pyrolyzed composite catalyst, a pyrolyzed composite catalyst obtainable by the process, and an electrode comprising the pyrolyzed composite catalyst are also provided. It also relates to the use of the pyrolyzed composite catalyst as an anode catalyst for the electrolytic oxygen evolution reaction in an electrochemical device, as well as an electrochemical device comprising the electrode as defined herein.
C25B 9/23 - Cellules comprenant des électrodes fixes de dimensions stablesAssemblages de leurs éléments de structure avec des diaphragmes comprenant des membranes échangeuses d'ions dans ou sur lesquelles est incrusté du matériau pour électrode
C25B 11/052 - Électrodes comportant un substrat et un ou plusieurs revêtements électro-catalytiques
C25B 11/095 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques au moins un des composés est de type organique
C25B 13/02 - DiaphragmesÉléments d'espacement caractérisés par la configuration ou la forme
38.
PHOTOVOLTAIC SYSTEM FOR LOW SOLAR ELEVATION ANGLES
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (Espagne)
Inventeur(s)
Ripalda Cobián, José María
Abrégé
A photovoltaic system, and an assembly method, for maximizing electric power production during low solar elevation angles, including at least a bifacial photovoltaic module, disposed on a substantially vertical first plane, mounted on a structural support and placed substantially facing the east on one side and the west on the other side, and at least two specular or metallic reflectors facing each side of the bifacial photovoltaic module at an angle of 73°±20° relative to the vertical. The reflectors are shaped or structured so that a fraction of the sun-light incident along a direction that is parallel to the photovoltaic module is redirected towards the photovoltaic module, thus maximizing the electric power production for conditions of low solar elevation such as winter, early morning and late afternoon, and protecting the photovoltaic module from overheating during noon and summer.
H02S 40/22 - Moyens réflecteurs ou concentrateurs de lumière
H02S 20/23 - Structures de support directement fixées sur un objet inamovible spécialement adaptées pour les bâtiments spécialement adaptées aux structures de toit
39.
IMAGE ANALYSIS METHOD AND SYSTEM FOR DETERMINING INTRACELLULAR FLUCTUATIONS
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Cano Tortajada, Álvaro
Tamayo De Miguel, Javier
Ruz Martínez, José Jaime
Calleja Gómez, Montserrat
Puerto Belda, Verónica
Millá Pardo, Carmen
Monteiro Kosaka, Priscila
Lopez Yubero, Marina Pilar
Abrégé
The invention relates to an image analysis system and method for determining intracellular fluctuations in a physiological medium, comprising a quantitative digital holographic microscope; an incubator that maintains a set of cells under optimal physiological conditions, in which the reference substrate and regions of interest are defined; and a processing module configured to: obtain a set of time-lapse images; determine the substrate and measure and spatially average a signal on said substrate; define a set of regions of interest and temporally average the signal measured in said regions of interest; calculate the signal fluctuation; define a noise fluctuation as a linear combination of average signals from a set of substrates; and iteratively calculate a corrected fluctuation value.
SUSPENSION OF CHIPS IN INKS, PAINTS OR VARNISHES, METHOD OF PRODUCTION AND USE FOR TRANSFERRING THE CHIPS TO COMPLEX SURFACES USING WRITING, PRINTING OR PAINTING DEVICES
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Plaza Plaza, José Antonio
Agusil Antonoff, Juan Pablo
Abrégé
The present invention relates to a suspension of chips that can be directly used on spatially and geometrically complex surfaces to provide these surfaces with said chips by means of writing, painting or printing devices, and to its method of production. The present invention further relates to the use of the suspension for decoration, marking, anti-forgery or antifraud, encryption, as sensors, as actuators, and for manufacturing electronic devices, and to the use of the suspension for determining the dimensions of the channels of a writing, painting or printing device.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Guillamón Navarro, José Manuel
Muñiz Calvo, Sara
Valera García, Elena
Planells Cárcel, Andrés
Abrégé
The present invention relates to a recombinant Saccharomyces cerevisiae cell comprising the nucleotide sequences that encode for a L-tryptophan decarboxylase enzyme, a tryptamine 5-hydroxylase enzyme and a modified ARO4 K229L enzyme. Said cell is capable of producing serotonin from a simple carbon source, such as glucose, and from ammonia as a nitrogen source.
C12N 15/81 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour champignons pour levures
C12N 1/19 - LevuresLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12P 1/02 - Préparation de composés ou de compositions, non prévue dans les groupes , utilisant des micro-organismes ou des enzymesProcédés généraux de préparation de composés ou de compositions utilisant des micro-organismes ou des enzymes utilisant des champignons
C12P 17/10 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle l'azote comme unique hétéro-atome du cycle
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
De Teresa Nogueras, José María
Herrer Jiménez, Isabel Lucía
Salvador Porroche, Alba
Sangiao Barral, Soraya
Cea Mingueza, Pilar
Abrégé
A system and method for manufacturing electrical contacts and electronic gate contacts, wherein the system comprises a main chamber; a support situated in the main chamber and intended to hold the manufacturing material; an ion column, situated in the main chamber, perpendicular to the support, and intended to irradiate the manufacturing material with an ion beam; and an electron column, situated in the main chamber, parallel to the ion column, and intended to irradiate the manufacturing material with an electron beam. The manufacturing system and method can be used to obtain electrical contacts or electronic gate contacts in the main chamber through the combined use of ion and electron irradiation applied to an organometallic film.
C23C 18/14 - Décomposition par irradiation, p. ex. par photolyse, rayonnement corpusculaire
C23C 18/08 - Revêtement chimique par décomposition soit de composés liquides, soit de solutions des composés constituant le revêtement, ne laissant pas de produits de réaction du matériau de la surface dans le revêtementDépôt par contact par décomposition thermique caractérisée par le dépôt d'un matériau métallique
H01J 37/317 - Tubes à faisceau électronique ou ionique destinés aux traitements localisés d'objets pour modifier les propriétés des objets ou pour leur appliquer des revêtements en couche mince, p. ex. implantation d'ions
43.
LONG-CHAIN LINEAR TERMINAL ALKENE AROMATISATION CATALYSED BY RUTHENIUM SUPPORTED ON SOLIDS
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
Bacic, Matea
Leyva Perez, Antonio
Mon Conejero, Marta
Abrégé
The present invention discloses a method for the synthesis of alkylated benzenes, such as xylene and ethylbenzene, with yields greater than 50%, by means of the isomerisation, cyclisation and dehydrogenation of the corresponding long-chain linear terminal alkenes on ruthenium catalytic species supported on solids. The method comprises at least the following steps: - A first step in which the long-chain linear terminal alkene is put into contact with a supported ruthenium catalyst. - A second step of heating the obtained mixture. - A third step of recovering the product and the catalyst using washing and filtration.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Gutiérrez Adán, Alfonso
Rizos, Dimitrios
Fernandez Gonzalez, Raúl
Beltran Breña, Paula
Abrégé
The present invention relates to an in vitro method for evaluating the fertilising capacity of sperm and/or for selecting capacitated, acrosome-free sperm that penetrate the zona pellucida (ZP), by means of the use of zonae pellucidae previously isolated from bovine oocytes obtained from ovaries in slaughterhouses, and heterologous in vitro fertilisation between sperm (preferably human sperm) and the zonae pellucidae isolated from bovine oocytes. Furthermore, the present invention relates to the use of the selected sperm as a medicament, particularly in assisted reproductive therapies.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (Espagne)
Inventeur(s)
Murillo Villuendas, Ramón
García San Miguel, Gonzalo
Abrégé
The apparatus of the invention comprises a cylindrical inner chamber (4) and a cylindrical outer chamber (5), coaxial with one another, the inner chamber (4) housing an auger (6) which is intended to move polymeric material continuously inside the inner chamber (4) and which has a helix (8) around the screw shaft. The apparatus also includes gas outlets (17) and solids outlets (18). The outer chamber (5) is fed with hot gases for thermochemical conversion in the inner chamber (4). The apparatus also has at least one deflector (19) arranged in the upper portion between the upper chamber (5) and the lower chamber (4), to produce a pressure loss in the hot gases so as to force said hot gases to flow predominantly or exclusively through the lower part of the outer chamber (5). It allows greater energy efficiency and durability.
C10G 1/10 - Production de mélanges liquides d'hydrocarbures à partir de schiste bitumineux, de sable pétrolifère ou de matières carbonées solides non fusibles ou similaires, p. ex. bois, charbon à partir de caoutchouc ou de déchets de caoutchouc
C10B 7/02 - Fours à coke comportant des moyens mécaniques pour le transport de la matière première à l'intérieur du four avec racleurs rotatifs
C10B 7/10 - Fours à coke comportant des moyens mécaniques pour le transport de la matière première à l'intérieur du four avec transporteurs à vis
C10B 47/34 - Autres procédés dans des fours munis de transporteurs mécaniques avec dispositifs racleurs rotatifs
C10B 47/44 - Autres procédés dans des fours munis de transporteurs mécaniques avec des transporteurs à vis
C10B 53/07 - Distillation destructive spécialement conçue pour des matières premières solides particulières ou sous forme spéciale de matières polymères synthétiques, p. ex. pneumatiques
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT DE BARCELONA (Espagne)
Inventeur(s)
Gomis-Rüth, Francesc Xavier
Del Amo Maestro, Laura
Dos Mendes Rei, Soraia Ines
Eckhard, Ulrich
Rodríguez Banqueri, Arturo
Guevara Puig, Tibisay
Pérez Cano, Francisco
Rodríguez Lagunas, María José
Franch Masferrer, Àngels
Girbal Gonzalez, Marina
Abrégé
The present invention relates to a protein comprising the amino acid sequence SEQ ID NO: 1, compositions comprising the protein, and uses of said compositions in the treatment of diseases caused by the presence of peptide antigens in gluten, in the treatment of gluten-containing foods, or in the preparation of gluten-free food products.
Consejo Superior de Investigaciones Cientificas (CSIC) (Espagne)
Inventeur(s)
Hernandez Sanchez, Catalina
De La Rosa Cano, Enrique
Abrégé
The present invention relates to a synthetic peptide analog of the Preimplantation factor (PIF) peptide with a sequence length of maximum 20 amino acids consisting in the sequence Xaa1 Xaa2 R3 I4 K5 P6 Xaa7-20 (SEQ ID No1): wherein Xaa can be any amino acid for use in the treatment and/or prevention of Retinitis Pigmentosa and a pharmaceutical composition comprising one or more synthetic peptide analog from PIF peptides and one or more acceptable carriers.
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
A61K 38/00 - Préparations médicinales contenant des peptides
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Ruiz Ruiz, Luisa María
Jiménez Ruiz, Antonio Ramón
Abrégé
A gait segmentation method is described, comprising the steps of determining (1) by means of a position sensor the positions of a horizontal path (5) of a foot (6), calculating (2) horizontal displacements of the foot (6) from the positions of the path of the foot, and gait segmentation (3) from the horizontal displacements. The segmentation (3) identifies desired temporal events, phases or subphases of gait by comparing the horizontal displacements of the foot with a constant foot displacement threshold value independent of the gait mode without the need for prior training data or specific thresholds for each type of gait, allowing the analysis, study and characterization of movement in fields such as human gait research, physiotherapy, rehabilitation, sport, dance and medicine.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
Galve Conde, Fernando
Alonso Otamendi, Joseba
Benlloch Baviera, José María
Abrégé
The invention relates to a main magnet (1) comprising a plurality of rings (9, 10) with hollow sections (11, 12) forming a bore (2). Each ring (9, 10) comprises a plurality of blocks (19) of permanent magnetic material arranged in one or more layers (9', 9'', 10', 10''), each layer (9', 9'', 10', 10'') comprising a dipolar elliptical Halbach array. The minor axes of the ellipses of said layers (9', 9'', 10', 10'') are substantially parallel to one another. The bore (2) of the main magnet (1) is suitable for housing a magnetic gradient system (5) extending along the longitudinal axis (8), and wherein said magnetic gradient system (5) covers at least 70% of the entire length of the main magnet (1). The invention also relates to an MRI scanner (3) comprising said main magnet (1) and to the method of manufacturing same.
G01R 33/38 - Systèmes pour produire, homogénéiser ou stabiliser le champ magnétique directeur ou le champ magnétique à gradient
G01R 33/383 - Systèmes pour produire, homogénéiser ou stabiliser le champ magnétique directeur ou le champ magnétique à gradient utilisant des aimants permanents
G01R 33/3873 - Compensation des inhomogénéités utilisant des corps ferromagnétiques
50.
METHOD TO INCREASE CO2 CAPTURE EFFICIENCIES BY CARBONATION AND RELATED CARBONATOR
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Abanades García, Juan Carlos
Arias Rozada, Borja
Abrégé
This invention discloses a method to increase the CO2 capture efficiency in a fluidized bed carbonator of CaO or Ca(OH)2 by exploiting the characteristics of a solid entrainment zone at the exit of the carbonator, where fine solids are in contact with the gas exiting the carbonator. The method being characterized by selectively cooling said entrainment zone to 500-600° C. by feeding the to the beginning of a solid entrainment zone part of the make-up flow of limestone at ambient temperature, by installing a heat exchanger section of a water/steam circuit, by spraying water or by feeding a flow of Ca(OH)2 powder at ambient temperature to capture the CO2 from the gas already depleted in CO2 that leaves the denser region of solids that is present at the bottom of the carbonator.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (Allemagne)
SCREENSYS GMBH (Allemagne)
Inventeur(s)
Sánchez Testillano, Pilar
Martínez Gil, Ana
Gil Ayuso-Gontán, Carmen
Carneros García, Elena
Pérez Pérez, Yolanda
Palme, Klaus
Welsch, Ralf
Pandey, Saurabh
Abrégé
The present invention relates to the use of PDE inhibitors, preferably mammalian PDE inhibitors, to enhance the induction of in vitro plant cell reprogramming towards plant embryogenesis or microcallus formation for further plant regeneration. The present invention also relates to a method to promote this process comprising culturing an isolated plant material with at least one PDE inhibitor, preferably mammalian PDE inhibitor.
Consejo Superior de Investigaciones Científicas (CSIC) (Espagne)
Universidad de Sevilla (Espagne)
Inventeur(s)
Moreno Herrero, Jorge
Haas, Heinrich
Erbar, Stephanie
Stahl, Theo Benjamin
García Fernández, José Manuel
Benito Hernández, Juan Manuel
Lopez Fernandez, Jose
Ortiz Mellet, Maria Del Carmen
De La Cruz Ruiz, Noelia
González Cuesta, Manuel
Jacobus Ambuludi, Egon Jack
Vlatkovic, Irena
Abrégé
The present disclosure provides complexes comprising: i) a cationic oligosaccharide comprising one or more cationic moieties bonded to a trehalose, a sucrose, or a gluco-n-oligosaccharide moiety, where n is 2-6; ii) a surfactant; and iii) one or more additives selected from: a sterol, a helper lipid, an immunomodulator, and a targeting molecule; and uses thereof.
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus
C12N 15/88 - Introduction de matériel génétique étranger utilisant des procédés non prévus ailleurs, p. ex. co-transformation utilisant la micro-encapsulation, p. ex. utilisant des vésicules liposomiques
Consejo Superior de Investigaciones Científicas (CSIC) (Espagne)
Inventeur(s)
Moreno Herrero, Jorge
Haas, Heinrich
Erbar, Stephanie
García Fernández, José Manuel
Benito Hernández, Juan Manuel
Lopez Fernandez, Jose
Abrégé
The present disclosure provides complexes comprising a cationic oligosaccharide and an RNA, wherein the cationic oligosaccharide comprises a plurality of cationic moieties bonded to a trehalose, a sucrose, or a gluco-n-oligosaccharide moiety, where n is 2-6, and a ratio of N/P in the complex is less than 20:1
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
TECHNISCHE UNIVERSITÄT DARMSTADT (Allemagne)
UNIVERSIDAD PÚBLICA DE NAVARRA (Espagne)
FUNDACION TECNALIA RESEARCH & INNOVATION (Espagne)
KATHOLIEKE UNIVERSITEIT LEUVEN (Belgique)
MICROLIGHT3D (France)
POLITECNICO DI TORINO (Italie)
UNIVERSIDAD DEL PAÍS VASCO / EUSKAL HERRIKO UNIBERSITATEA (Espagne)
Inventeur(s)
Sánchez Dolado, Jorge
Goracci, Guido
Ayuela Fernández, Andrés
Arrese-Igor Irigoyen, Silvia
Beruete Díaz, Miguel
Liberal Olleta, Íñigo
Lezaun Capdevilla, Carlos
Torres García, Alicia
Pérez Escudero, José Manuel
Gaitero Redondo, Juan José
Prabhu, Achutha
Koenders, Edduardus
Mankel, Christophe
Ukraincyk, Neven
Peralta, Ignacio
Cagnoni, Mateo
Capelluti, Federica
Sylvander, Antoine
Barbier, Denis
Allacker, Karen
Adams, Nick
Abrégé
233 lower than 0.05 % by weight with respect to the total weight of the OPC binder, wherein the grain size is below 25 µm, - water, wherein the weight ratio between water and the OPC binder is between 0.2 to 0.6, - an addition in a proportion between 0.1% and 50% by weight with respect to the weight of the OPC binder and wherein the resulting DRCCC has a pore size below 6 µm as defined by mercury intrusion porosimetry, that can optionally comprise micropatterns, and to its use in the construction industry, such as building construction, in civil works such as reservoirs, bridges, dams and sewers, in solar cell technology or in urban architectural design.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Murillo Rodríguez, Gonzalo
Duque Duque, Marcos
Abrégé
The present invention belongs to the field of electrically powered functional structures, specifically monolithic functional structures comprising at least one functional structure (such as a resonator, sensor, energy collector, etc.) and at least one piezoelectric material. In addition, the at least one functional structure and the at least one piezoelectric material form part of a single piece and are electrically connected together. The invention relates to the monolithic functional structure and to a method for 3D printing the monolithic functional structure.
H10N 30/05 - Fabrication de dispositifs piézo-électriques ou électrostrictifs multicouches ou de leurs parties constitutives, p. ex. en empilant des corps piézo-électriques et des électrodes
H10N 39/00 - Dispositifs intégrés, ou ensembles de plusieurs dispositifs, comportant au moins un élément piézo-électrique, électrostrictif ou magnétostrictif couvert par les groupes
H02N 2/18 - Machines électriques en général utilisant l'effet piézo-électrique, l'électrostriction ou la magnétostriction fournissant une sortie électrique à partir d'une entrée mécanique, p. ex. générateurs
H10N 30/30 - Dispositifs piézo-électriques ou électrostrictifs à entrée mécanique et sortie électrique, p. ex. fonctionnant comme générateurs ou comme capteurs
H10N 30/50 - Dispositifs piézo-électriques ou électrostrictifs avec une structure empilée ou multicouche
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Martínez, Ana
Gil, Carmen
Nozal, Vanesa
Palomo, Valle
Martín-Requero, Angeles
Martínez-González, Loreto
Pérez Cuevas, Eva M.
Abrégé
TTBK enzyme inhibitors of formula (I) are used for the treatment and/or prevention of tauopathies, such as Alzheimer's disease (AD), and/or TDP-43 pathologies, such as amyotrophic lateral sclerosis (ALS). R1 is selected from H and NH2, X is selected from O, S, CO and CH2O, R2, R3 and R4 are independently selected from: H, halogen, CF3, CN, NO2, NH2, C1-C3 alkyl and —O—C1-C3 alkyl. At least one of R2, R3 and R4 are H.
TTBK enzyme inhibitors of formula (I) are used for the treatment and/or prevention of tauopathies, such as Alzheimer's disease (AD), and/or TDP-43 pathologies, such as amyotrophic lateral sclerosis (ALS). R1 is selected from H and NH2, X is selected from O, S, CO and CH2O, R2, R3 and R4 are independently selected from: H, halogen, CF3, CN, NO2, NH2, C1-C3 alkyl and —O—C1-C3 alkyl. At least one of R2, R3 and R4 are H.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
Carbonell Olivares, Alberto Tomás
Darós Arnau, José Antonio
González Cisneros, Adriana Estela
Martín García, Tamara
Abrégé
The invention provides a plant viral vector comprising a heterologous nucleotide sequence that encodes, or corresponds to the RNA sequence of a functional minimal miRNA precursor, wherein said RNA sequence consists of S1 that is of a length of 56-400 ribonucleotides and that comprises regions R1, R2, R3, R4 and R5 directly linked to each other as indicated in formula (i): (i) 5'-R1-R2-R3-R4-R5-3', wherein: - R1 consists of the RNA sequence of a strand of a basal stem (BS) structure, - R2 consists of the RNA sequence of a miRNA, - R3 comprises an RNA sequence that has a length of at least 8 nucleotides, - R4 consists of an RNA sequence that base pairs with the RNA sequence of R2 to form a miRNA/miRNA* duplex, - R5 consists of the RNA sequence complementary to R1 in the BS comprising R1, and wherein the RNA sequence S1 forms a stem-loop structure where the stem comprises regions R1, R2, R4 and R5 wherein region R1 base pairs with region R5 and region R2 base pairs with region R4, and the loop comprises a sequence of at least 4 contiguous nucleotides of region R3. The invention also provides a virus encoded by or comprising the viral vector, a plasmid comprising or encoding the viral vector, a bacterium comprising the plasmid, a plant comprising the viral vector, the virus or the bacterium, a plant extract from the plant, and a method for obtaining the plant and a method for obtaining the extract.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
Carbonell Olivares, Alberto Tomás
Darós Arnau, José Antonio
González Cisneros, Adriana Estela
Abrégé
The invention provides a viral vector, particularly a plant viral vector, comprising a heterologous nucleotide sequence that encodes or corresponds to an RNA sequence S1 that has a length of 52-350 ribonucleotides and that comprises regions R1, R2 and R3 directly linked to each other as indicated in formula (i): (i) 5'-R1-R2-R3-3', wherein: - region R1 consists of the target site of a sRNA, - region R2 consists of an RNA sequence of 11 ribonucleotides, and - Region R3 consists of the RNA sequence of one or more siRNAs, wherein when R3 is formed by more than one siRNA sequence, the siRNA sequences are directly linked to each other, particularly wherein the RNA sequence consisting of S1 is the RNA sequence of a functional syn-tasiRNA precursor. The invention also provides a virus encoded by or comprising the viral vector, a plasmid comprising or encoding the viral vector, a bacterium comprising the plasmid, a plant comprising the viral vector, the virus or the bacterium, a plant extract from the plant, and a method for obtaining the plant.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSIDAD PABLO DE OLAVIDE (Espagne)
Inventeur(s)
Gil Ayuso-Gontán, Ana
Martínez Gil, Ana
Smani, Younes
Morales Tenorio, Marcos
García Rubia, Alfonso
Abrégé
The invention relates to new derivatives useful as antibacterial agents, specifically to a compound of formula (I) for use to treat and/or prevent a disease caused by a bacterium, in particular wherein the disease is caused by a gram-negative bacterium, such as Acinetobacter baumannii or Escherichia coli, wherein group R1-R4, X and Y have the meaning defined in the description. Formula (I)
C07D 409/10 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
C07D 407/10 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
C07D 403/10 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
C07D 417/10 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
C07D 413/10 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
A METHOD FOR MAGNETIC CONVERSION FROM PARAMAGNETIC TO FERROMAGNETIC OF MICROPOROUS METAL MATERIALS, CONVERTED FERROMAGNETIC MICROPOROUS METAL MATERIAL AND USES THEREOF
FUNDACIÓ INSTITUT CATALÀ DE NANOCIÈNCIA I NANOTECNOLOGIA (ICN2) (Espagne)
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS (ICREA) (Espagne)
Inventeur(s)
Nogués Sanmiquel, Josep
Sepúlveda Martínez, Borja
Esplandiu Egido, Maria Jose De Monserrat
Fons, Arnau
Lafuente, Aritz
Abrégé
The present invention is directed to a new method for magnetic conversion from paramagnetic to ferromagnetic of a raw material being composed of microporous austenitic stainless-steel. The method comprises an annealing treatment, and then a cooling down treatment. The invention is also directed to a converted ferromagnetic microporous stainless-steel material obtainable thereby with hydrophilic or with hydrophobic properties, as well as to their uses as heat generator for use in applications where an efficient heat exchanger for fluids is required. The heat generator is provided by means of magnetic field and/or optical absorption.
C21D 6/00 - Traitement thermique des alliages ferreux
C21D 8/12 - Modification des propriétés physiques par déformation en combinaison avec, ou suivie par, un traitement thermique pendant la fabrication d'objets à propriétés électromagnétiques particulières
62.
HETEROMETALLIC DIMER CATALYST STABILISED IN A METAL-ORGANIC FRAMEWORK WITH METHYLCYSTEINE AND USE THEREOF IN ACETYLENE SEMI-HYDROGENATION
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
Pardo Marín, Emilio José
Ferrando Soria, Jesús
Leyva Pérez, Antonio
Ballesteros Soberanas, Jordi
Bacic, Matea
Abrégé
The invention relates to a heterobimetallic dimer catalyst stabilised by thioether residues of the methylcysteine of a metal–organic framework (MOF) and represented as X1-Y1-MOF, which has the general chemical formula: X1-Y1@{MIICuII 6[(S,S)–Mecysmox]3(OH)2(H2O)}. nH2O, where: - X and Y are metals, where X is different from Y; - X is selected from Pd, Pt and Ni; - Y is selected from Pd, Fe, Ni, Cu, Co, Au, Pt, Sn, Rh and Ag; - Mecysmox means bis[S-methylcysteine]oxalyl diamide; - M is selected from Ca, Sr and Ba; and - n = 0-20, both values inclusive. The invention further relates to the use thereof in hydrogenation reactions, particularly in acetylene semi-hydrogenation.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
González Gómez, Icíar
Salehi Jiménez, Nadia
Valdivieso Martínez, Alba
Luzuriaga González, Jon
Abrégé
The invention relates to an ultrasonic device and an associated method for generating three-dimensional cell spheroids. The device comprises a polymer structure (2) of acoustically soft material with acoustic impedance similar to that of a liquid medium to be treated, which in turn comprises a set of containers (3) coupled to an ultrasonic actuator (1) on the bottom part thereof. The device allows three-dimensional cell spheroids to be generated from liquid suspensions in short periods of time of a few minutes and is also valid for particles or other micro-elements, with applications in research or analysis in tumour biology, tissue engineering and clinical analysis and research concerning molecular targets in personalised medicine, thus replacing the use of animals.
C12N 13/00 - Traitement de micro-organismes ou d'enzymes par énergie électrique ou ondulatoire, p. ex. par magnétisme, par des ondes sonores
C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
64.
SYSTEM AND METHOD FOR ENCODING AND CORRECTING BB84 PROTOCOL POLARISATION STATES
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Llanos Velasco, Adrián
Arteaga Díaz, Pablo
Fernández Marmol, Verónica
Abrégé
The invention relates to a system for encoding and correcting BB84 protocol polarisation states, which implements a method for measuring the polarisation error by carrying out said measurement before a step of transmitting the information and can be used in any system in which it is desired to implement quantum key distribution (QKD).
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSIDAD COMPLUTENSE DE MADRID (Espagne)
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III F.S.P. (Espagne)
Inventeur(s)
Del Pozo Losada, Jesús
Marcilla Díaz, Antonio
Del Pozo Losada, Carlos
Sánchez López, Christian, Miquel
Sánchez Sancho, Francisco, Antonio
García Csáky, Aurelio
Oliver Pérez, Eduardo
Ibáñez Cabeza. Borja
Baquero Gálvez, María, Gracia
Roscales García, Silvia
Cumella Montánchez, José, María
Abrégé
The present invention relates to the chemical synthesis and production of compounds derived from imidazo[1,2-a]pyridine of formula I, wherein R2, R3, R5, R6and R7 have the meanings indicated in the description; a method for obtaining same; and the therapeutic use thereof as a pharmaceutical composition for anti-inflammatory use in vitro and in vivo in diseases involving inflammatory and pro-fibrotic processes.
A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
66.
DEVICE FOR THE DETECTION OF GAMMA RAYS BASED ON SEGMENTED METASCINTILLATOR BLOCK DETECTORS
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
González Martínez, Antonio Javier
Lecoq, Paul
Benlloch Baviera, José María
Konstantinou, Georgios
Barrio Toala, John
Abrégé
A device for the detection of gamma rays to be used primarily in a PET scanner is based on a scintillator heterostructure combining the high stopping power of scintillators commonly used in PET scanners (such as L(Y)SO, BGO, etc.) and fast scintillators based on polymers loaded with fast emitting dyes or nanocrystals, or thin layers of nanocrystals or multiple quantum well structures. While the metascintillator block is read out in the monolithic or semi-monolithic arrangement, the fast scintillator is segmented so that it is read out by less photodetectors. The particular arrangement of this detector module allows combining all the important features of a high-performance Time-of-Flight PET (TOFPET) detector module, i.e. a high photoelectric detection efficiency for the gamma rays, a precise 3D information (including the depth of interaction DOI) of the gamma ray conversion in the module, good energy resolution and superior timing resolution.
G01T 1/20 - Mesure de l'intensité de radiation avec des détecteurs à scintillation
G01T 1/29 - Mesure effectuée sur des faisceaux de radiations, p. ex. sur la position ou la section du faisceauMesure de la distribution spatiale de radiations
CENTRO DE INVESTIGACIÓN EN AGRIGENÓMICA - CRAG (Espagne)
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT DE BARCELONA (Espagne)
UNIVERSITAT AUTÒNOMA DE BARCELONA (Espagne)
Inventeur(s)
Sánchez Coll, Nuria
Armengot Martínez, Laia
Salguero Linares, Jose Manuel
Ruiz Solaní, Nerea
Ventura Zamora, Salvador
Pallarès Goitiz, Irantzu
Santos Suárez, Jaime
Abrégé
The present invention provides a polypeptide having disaggregase activity for use in medicine, wherein the polypeptide comprises the sequence SEQ ID NO: 1 or SEQ ID NO: 2, or a variant thereof that retains the disaggregase activity, more particularly for use in the prevention or treatment of a disease or disorder associated with protein aggregates in a subject. The invention also provides an expression vector encoding the polypeptide for the same use, and uses and methods for eliminating or preventing the formation of a protein aggregate in a protein-containing composition. The invention also provides the use of the polypeptide for imaging a protein aggregate and for the diagnosis and prognosis of a disease associated with protein aggregates.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Ruiz Chamorro, Andrés
Fernández Mármol, Verónica
Cano Reol, Daniel
Abrégé
Pilot-tone-assisted demodulation procedure for coherent optical communication systems, specifically continuous-variable quantum key distribution (CV-QKD) systems, which allows compensation of random phase fluctuations in the lasers they use after acquiring the signal, solving the frequency-locking problem in a simple, efficient, and cost-effective manner.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
INSTITUT QUÍMIC DE SARRIÁ CETS FUNDACIÓ PRIVADA (Espagne)
Inventeur(s)
Alfonso Rodriguez, Ignacio
Carbajo López, Daniel
Pérez Ruiz, Yolanda
Bujons Vilás, Jordi
Prats Miravitllas, Eva
Guerra Rebollo, Marta
Abrégé
The invention relates to new spermine derivatives of Formula (I), wherein the meaning of the groups R1, R2, n and m is defined in the description, to a pharmaceutical composition thereof and to their use as heparin antidotes in the control of blood coagulation. The invention was developed based on the realization that it would be desirable to have improved heparin antidotes with good anticoagulant rates, based on simple, easy to produce synthetic small molecules.
C07C 215/50 - Composés contenant des groupes amino et hydroxy liés au même squelette carboné ayant des groupes hydroxy liés à des atomes de carbone d'au moins un cycle aromatique à six chaînons et des groupes amino liés à des atomes de carbone acycliques ou à des atomes de carbone de cycles autres que des cycles aromatiques à six chaînons du même squelette carboné avec des groupes amino reliés au cycle aromatique à six chaînons, ou au système cyclique condensé contenant ce cycle par l'intermédiaire de chaînes carbonées qui ne sont pas substituées de plus par des groupes hydroxy avec des groupes amino et le cycle aromatique à six chaînons, ou le système cyclique condensé contenant ce cycle, liés au même atome de carbone de la chaîne carbonée
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
C07C 217/58 - Composés contenant des groupes amino et hydroxy éthérifiés liés au même squelette carboné ayant des groupes hydroxy éthérifiés liés à des atomes de carbone d'au moins un cycle aromatique à six chaînons et des groupes amino liés à des atomes de carbone acycliques ou à des atomes de carbone de cycles autres que des cycles aromatiques à six chaînons du même squelette carboné avec des groupes amino reliés au cycle aromatique à six chaînons, ou au système cyclique condensé contenant ce cycle, par l'intermédiaire de chaînes carbonées qui ne sont pas substituées de plus par des atomes d'oxygène liés par des liaisons simples avec des groupes amino et le cycle aromatique à six chaînons, ou le système cyclique condensé contenant ce cycle, liés au même atome de carbone de la chaîne carbonée
70.
PROCESS FOR THE PHOTOCATALYTIC OXIDATION OF ALKANES AND AROMATIC HYDROCARBONS
B01J 31/14 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques contenant des composés organométalliques ou des hydrures métalliques d'aluminium ou de bore
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSIDAD DE HUELVA (Espagne)
ATLANTIC COPPER, S.L.U. (Espagne)
Inventeur(s)
Pérez Romero, Pedro J.
Díaz Requejo, M. Mar
Pizarro Javier, Juan Diego
Portela Rodríguez, Raquel
Ávila García, Pedro
Romero Vásques, Flavio Jesús
Ríos Ransanz, Guillermo
Ruiz Oria, Irene
Mejía Pérez, Alberto
Abrégé
2 22 in emergency point emissions of copper factories. This material comprises calcium hydroxide as an acidic gas adsorbent element, together with sepiolite as a binding agent and sodium and potassium bicarbonates as basifying elements and may be obtained by an easy process which requires mainly a dry treatment at temperatures below 60ºC.
B01J 20/04 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant des composés des métaux alcalins, des métaux alcalino-terreux ou du magnésium
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
B01J 20/12 - Argiles d'origine naturelle ou terres décolorantes
72.
METHOD FOR INHIBITING MOLECULAR DIHYDROGEN DISSOCIATION ON NOBLE METALS USING 1,4-ENEDIOLS
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSITAT POLITÈCNICA DE VALÈNCIA (Espagne)
Inventeur(s)
Ballesteros Soberanas, Jordi
Mon Conejero, Marta
Leyva Perez, Antonio
Abrégé
The present invention discloses a method for inhibiting molecular hydrogen dissociation on noble metal materials and surfaces using 1,4-enediols, such as 2,4,7,9-tetramethyldecyne-4,7-diol, in order to deactivate the splitting of the molecular hydrogen and the formation of hydrides on the surface of said materials. Said deactivation process is intended for industrial uses, such as, but not limited to, modifying catalysts, creating hydrogen storage materials and protecting metal materials. The process comprises at least the following steps: - A first step in which the 1,4-enediol, or a mixture thereof, is brought into contact with a material containing a noble metal. - A second step of stirring, and heating or subjecting to pressure. - A third step of recovering the material.
B01J 31/02 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSIDAD DE SEVILLA (Espagne)
Inventeur(s)
Rico Gavira, Victor
Borrás Martos, Ana Isabel
Rodríguez González-Elipe, Agustín
Montes Montañez, Laura
López López, Marta
García Valenzuela, Aurelio
López Santos, Mª Carmen
Oliva Ramírez, Manuel
Abrégé
A device has a piezoelectric or ferroelectric substrate on which ice is deposited. Electrodes are connected to the substrate. A vector network analyzer is connected to the electrodes and configured to determine the resonant frequency of the substrate. An excitation module including a function generator communicates with the vector network analyzer and is connected to an amplifier. The amplifier is connected to the electrodes. The excitation module uses an automatic switch to apply to the electrodes an AC electrical signal having a frequency coinciding with the resonant frequency measured in the vector network analyzer and which changes gradually as the ice melts.
B06B 1/02 - Procédés ou appareils pour produire des vibrations mécaniques de fréquence infrasonore, sonore ou ultrasonore utilisant l'énergie électrique
B06B 1/06 - Procédés ou appareils pour produire des vibrations mécaniques de fréquence infrasonore, sonore ou ultrasonore utilisant l'énergie électrique fonctionnant par effet piézo-électrique ou par électrostriction
74.
METHOD FOR THE PRODUCTION OF ACTIVATED CHARCOAL SUITABLE FOR THE REMOVAL OF ORGANIC POLLUTANTS IN WATER FROM WASTE RICE CROP AND PINE WOOD BIOMASS
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Undabeytia López, Tomás
De La Rosa Arranz, José María
Almeida De França Miller, Ana Zelia
Diéguez Alonso, Alba
Behrendt, Frank
Almuiña Villar, Hernán
Abrégé
The present invention relates to a method for obtaining an activated charcoal capable of removing, by means of adsorption and filtration, organic water pollutants, particularly emerging organic pollutants such as medicinal drugs. Said method is based on pyrolysis and physical activation in the absence of oxygen, with water vapour (40 % v/v) from a mixture of waste rice crop and pine wood biomass. The product obtained by means of the present invention belongs to the field of water purification through the removal of pollutants.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Castellanos Gómez, Andres
Riquelme Ballesta, Juan José
Sozen, Yigit
Abrégé
The present invention relates to a method for preparing coatings made of two-dimensional material by means of massive parallel mechanical exfoliation. Said method comprises pressing rollers and making them roll with each other at a range of speeds and pressures that results in coatings made of two-dimensional material with flakes made of two-dimensional material having a lateral size and a high front thickness. The method has a low level of complexity compared to existing methods and involves less energy than other methods. The present invention further relates to the coating obtained and uses thereof as semiconductor devices.
B32B 37/12 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par l'usage d'adhésifs
B32B 37/14 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par les propriétés des couches
77.
POLYPURINE REVERSE HOOGSTEEN HAIRPINS AND PARALLEL CLAMPS AND THEIR USE AS BIOSENSORS
CONSEJO SUPERIOR INVESTIGACIONES CIENTIFICAS (CSIC) (Espagne)
UNIVERSITAT DE BARCELONA (Espagne)
CONSORCIO CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED (Espagne)
Inventeur(s)
Martínez De La Fuente, Jesús
Cuestas Ayllón, Carlos
Grazú Bonavía, María Valeria
Fernández Sánchez, César
Gutiérrez Capitán, Manuel
Baldi Coll, Antonio
Eritja Casadellà, Ramon
Marco Colás, María Pilar
Vilaplana Holgado, María Luisa
Aviñó Andrés, Ana María
Ciudad Gómez, Carlos Julián
Noé Mata, Verónica
Abrégé
The present invention relates to an in vitro method for detecting at least one target poly-nucleotide in a test sample, wherein the method comprises the steps of contacting the test sample with a first oligonucleotide and a second oligonucleotide and detecting the hybridization between the first and the second oligonucleotides to the at least one target polynucleotide. The present invention also relates to devices or systems to implement the method, and kits of parts comprising said oligonucleotides.
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
C12Q 1/6816 - Tests d’hybridation caractérisés par les moyens de détection
C12Q 1/6888 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes
78.
SYSTEM FOR ASSESSING THE TOUGHNESS OF LONGITUDINAL HIGH FREQUENCY INDUCTION OR RESISTANCE WELDS IN STEEL TUBES AND ASSOCIATED METHOD
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Fernández Serrano, Ricardo
Peña Fernández, Mª Carmen
Abrégé
The present invention falls within the technical field of systems and methods for the assessment of longitudinal welds in steel tubes, and more specifically of longitudinal welds made by high-frequency induction welding (HFW) or electric resistance welding (ERW), and consists of a system for the assessment of the toughness of longitudinal high-frequency induction or resistance welds in steel tubes, and an associated method.
G01N 21/952 - Inspection de la surface extérieure de corps cylindriques ou de fils
G01N 21/954 - Inspection de la surface intérieure de corps creux, p. ex. d'alésages
B23K 31/12 - Procédés relevant de la présente sous-classe, spécialement adaptés à des objets ou des buts particuliers, mais non couverts par un seul des groupes principaux relatifs à la recherche des propriétés, p. ex. de soudabilité, des matériaux
B65B 51/22 - Application ou production de chaleur ou de pression ou les deux à la fois par friction, par des ultrasons ou par haute fréquence
G01N 1/28 - Préparation d'échantillons pour l'analyse
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (Espagne)
Inventeur(s)
Ali, Ghaffarinejad
Angel, Barranco Quero
Xavier, García Casas
Ana Isabel, Borras Martos
Juan Ramón, Sánchez Valencia
Abrégé
An energy harvesting device for obtaining instantaneous energy from drops without needing of moving the drops along the device, in a reduced scale and combinable with other types of harvesting devices. the energy harvesting device comprising one or more triboelectric generators comprising a bottom electrode. a friction or triboelectric element placed over the bottom electrode, and at least two top exposed electrodes electrically connected placed over the triboelectric element and defining at least one gap between them. exposing the triboelectric element to the external environment so that on contacting a drop of liquid makes an electrical connection between the top electrodes varying instantaneously (microseconds range) the capacitance of the triboelectric generators.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Herraiz Pérez, Aitor
Herranz Rabanal, Fernando
Abrégé
The present invention relates to an iron oxide nanoparticle (IONP) doped with the metals Ga and Zn. Likewise, the present invention relates to the use of said nanoparticle as a positive contrast agent for magnetic resonance imaging (MRI), in particular, as a positive contrast agent (Ti-MRI). Therefore, the invention could belong to the field of metallic nanoparticles and magnetic resonance imaging (MRI).
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Plaza Plaza, José Antonio
Agusil Antonoff, Juan Pablo
Abrégé
The invention relates to a method for producing elongate planar microparticles (1) that increases the manufacturing yield of said microparticles (1) and comprises the steps of: preparing a structuring layer of a microparticle (1) starting material on a substrate (2); defining the shape of the microparticles (1) in the structuring layer by using a photolithography technique and an engraving technique that defines the thickness of the microparticles (1), where the shape of the microparticles (1) is such that it comprises an elongate central body (3) with longer sides and shorter sides, with at least two side wings (4) extending from the longer sides; and forming one or more feet (5) with a circular section in an upper portion of the substrate (2) that is under the structuring layer.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Reparaz, Juan Sebastian
Kai, Xu
Campoy-Quiles, Mariano
Abrégé
The method comprises the steps of providing a pump laser (1 ) with a Gaussian intensity distribution, providing a probe laser (2) with a laser intensity constant in time, harmonically modulating the power of the pump laser (1 ), reading a pump beam (25), measuring the phase of the pump beam (25) and setting it as zero-phase lag, measuring the phase lag of the probe beam (24), increasing the offset between the pump and probe beam (25, 24), repeating the steps to obtain the phase lag between the pump and probe beams (25, 24) as a function of the offset between them, plotting the phase lag as a function of the offset between the pump and probe beams (25, 24), and computing the slope that renders the thermal diffusivity of the studied sample (12).
G01N 25/18 - Recherche ou analyse des matériaux par l'utilisation de moyens thermiques en recherchant la conductivité thermique
G01K 11/125 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou utilisant le changement de couleur, de translucidité ou de réflectance utilisant les changements de réflectance
83.
METHOD FOR OBTAINING A MATERIAL BASED ON TRANSLUCENT PAPER AND WITH BARRIER PROPERTIES AND MATERIAL OBTAINED
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Marcoaldi, Chiara
Prieto López, Cristina
Lagarón Cabello, José María
Abrégé
The present invention belongs to the area of biodegradable and/or compostable materials with liquid, gas and vapour barrier properties and improved optical properties, for use in the packing industry, among others. In particular, the invention relates to the coating of paper with a biopolymer layer to provide same with barrier properties and improved optical properties. The invention also relates to a method for producing same.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Fernández Regúlez, Marta
Perez-Murano, Francesc
Bausells Roigé, Joan
Abrégé
The invention relates to a method for manufacturing semiconductor qubits, which allows the manufacturing of gate electrodes (8) and electrical contacts (12, 13) with high resolution and alignment precision, said method comprising the steps of: (figure 2) depositing metal (3) and dielectric (4) gate materials; depositing transfer material (5); (figure 3) performing a process of lithography and etching of guiding patterns (7); performing a process of directed self-assembly with lamellar copolymers; eliminating the layers of transfer material in accordance with the pattern generated by the directed self-assembly process; (figure 4) depositing a fine dielectric layer (9); depositing a dielectric interface layer (10); defining a guiding pattern by means of a lithography and etching process; performing a process of directed self-assembly with cylindrical copolymers; (figure 5) etching the fine dielectric layer up to the gate metal using the pattern generated by the directed self-assembly process; and depositing layers of metal (12, 13) to generate contacts and define a structure of contacts.
H01L 29/41 - Electrodes caractérisées par leur forme, leurs dimensions relatives ou leur disposition relative
H01L 29/423 - Electrodes caractérisées par leur forme, leurs dimensions relatives ou leur disposition relative ne transportant pas le courant à redresser, à amplifier ou à commuter
H01L 29/66 - Types de dispositifs semi-conducteurs
H01L 21/768 - Fixation d'interconnexions servant à conduire le courant entre des composants distincts à l'intérieur du dispositif
B82Y 10/00 - Nanotechnologie pour le traitement, le stockage ou la transmission d’informations, p. ex. calcul quantique ou logique à un électron
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (Espagne)
UNIVERSITAT POLITECNICA DE VALENCIA (Espagne)
Inventeur(s)
Prieto González, Gonzalo
Andres Marcos, Eva
García Farpon, Marcos
Abrégé
The present invention relates to a process for the direct synthesis of acetone from synthesis gas and a solid multicomponent catalyst; wherein said multicomponent catalyst integrates at least one carbonylation active component and one ketonisation active component; wherein said carbonylation component comprises a zeotype material having a network structure comprising 8-membered ring units; wherein said ketonisation component comprises a hydroxide, oxide or any combination thereof selected from the list of yttrium, zirconium, titanium, aluminium, silicon, vanadium, niobium, tantalum, chromium, molybdenum, manganese, zinc, gallium, indium, tin, bismuth, lanthanide elements, or any combination thereof.
C07C 45/49 - Préparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogènePréparation des chélates de ces composés par réaction avec le monoxyde de carbone
B01J 23/10 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe des terres rares
B01J 23/63 - Métaux du groupe du platine avec des terres rares ou des actinides
B01J 23/80 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe du cuivre ou des métaux du groupe du fer en combinaison avec des métaux, oxydes ou hydroxydes prévus dans les groupes avec du zinc, du cadmium ou du mercure
B01J 29/70 - Zéolites aluminosilicates cristallinesLeurs composés isomorphes de types caractérisés par leur structure spécifique non prévus dans les groupes
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Ania Castañón, Juan Diego
Cáceres Pablo, Inés
Abrégé
The invention relates to a polarization-control-assisted pulsed fiber laser that can be used to change the spectral characteristics, increase the energy and reduce the temporal width of ultrashort pulses in such a pulsed fiber laser, all through the controlled modification of the polarization properties of the light prior to the insertion of this light into a doped fiber amplifier. For this purpose, the laser (1) comprises a polarization control module (3), which adjusts the polarization of the signal optimally by modifying the spectral and gain response of the doped fiber amplifier (4), thus affecting the properties of the output pulsed signal.
H01S 3/10 - Commande de l'intensité, de la fréquence, de la phase, de la polarisation ou de la direction du rayonnement, p. ex. commutation, ouverture de porte, modulation ou démodulation
H01S 3/106 - Commande de l'intensité, de la fréquence, de la phase, de la polarisation ou de la direction du rayonnement, p. ex. commutation, ouverture de porte, modulation ou démodulation par commande de dispositifs placés dans la cavité
H01S 3/1118 - Absorbeurs saturables à semi-conducteurs, p. ex. miroirs absorbeurs saturables à semi-conducteurs [SESAM]Absorbeurs saturables à l'état solide, p. ex. à base de nanotubes de carbone [CNT]
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSIDAD AUTÓNOMA DE MADRID (Espagne)
CONSORCIO CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED (Espagne)
Inventeur(s)
Guillen Morales, Paula
Perona Abellon, Rosario
Sastre Garzon, Leandro
Fernandez-Varas, Beatriz
Gutierrez Rodriguez, Marta
Martin Martinez, Mercedes
Guerrero Lopez, Rosa
Abrégé
The present invention relates to a GSE24.2-derived peptide and its related uses. In particular, the present invention discloses a peptide comprising the amino acid sequence with SEQ ID NO. 1 on the condition that said peptide does not have the amino acid sequence with SEQ ID NO. 3, SEQ ID NO. 4, SEQ ID NO. 5, SEQ ID NO. 6, SEQ ID NO. 7, SEQ ID NO. 8, SEQ ID NO. 9, SEQ ID NO. 10, SEQ ID NO. 11, or SEQ ID NO. 64. The invention also relates to uses of said peptide in the prevention and/or treatment of individuals with diseases caused by cellular DNA damage or telomer shortening, for example.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
UNIVERSIDAD POLITÉCNICA DE CARTAGENA (Espagne)
Inventeur(s)
Burgos Olmos, Manuel Antonio
Bastir, Markus
Abrégé
Disclosed is a method that allows for the reconstruction of the geometry of a nasal cavity (1) and ensures that it achieves certain previously specified functional parameters, starting from the geometry corresponding to the pathological nasal cavity (1). The method comprises the steps of: obtaining a three-dimensional surface Si3D representing the pathological nasal cavity (1) of a user presenting a nasal pathology; obtaining n functional parameters and m geometric parameters of the Si3D; selecting a healthy nasal cavity (1) that has the closest functional parameters to the functional parameters of the Si3D, and the geometric parameters anatomically compatible with the Si3D; and obtaining a modified nasal cavity (1) by transforming the Si3D into the healthy nasal cavity (1 ).
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
89.
NANOEMULSIONS TO INHIBIT THE FORMATION OF BACTERIAL BIOFILMS
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Arroyo Urea, Eva María
Lázaro Díez, María
Garmendia García, Junkal
Herranz Rabanal, Fernando
González Paredes, Ana
Abrégé
The invention relates to nanoemulsions formed by an oil core of α-tocopherol and octadecylamine and covered by a surfactant layer, in combination with an antimicrobial peptide, preferably the peptide DJK5-C14 (modified DJK5), and the method for obtaining them. The invention also relates to the in vitro use of nanoemulsions for inhibiting the formation of Haemophilus influenzae biofilms, as well as their use as a medication for the treatment or prevention of diseases caused by H. influenzae.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Fernández De Cabo, Raquel
Villafranca Velasco, Aitor
González Andrade, David
Abrégé
The invention comprises an inlet port (1), outlet ports (2), a Y joint (3) with a shank (31) connected to the inlet port (1) and arms (32) connected to the outlet ports (2), and an SWG structure with a regular arrangement of segments of core material and cladding material, comprising a first region (4), in which the core material segments connect the first arm (32) and the second arm (32), and a second region (5), in which a first set of core material segments is connected to the first arm (32), and a second set of core material segments is connected to the second arm (32), wherein the first set of core material segments is separate from the second set of core material segments, and wherein the first set of core material segments and the second set of core material segments have a progressively narrowing width.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Criado Sanz, María
De Hita Fernández, María Jimena
Abrégé
The present invention relates to a method for immobilising spent nuclear-grade resins or a decontamination sludge and to a kit for implementing said method. Furthermore, the present invention relates to a binding material and to a mortar comprising the spent nuclear-grade resin or the decontamination sludge and to their respective production methods.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Ghaffarinejad, Ali
Barranco Quero, Angel
García Casas, Xabier
Borrás Martos, Ana Isabel
Sánchez Valencia, Juan Ramón
Abrégé
A triboelectric device that acts as self-powered transductor in a reduced scale to obtain physicochemical information instantaneously. The device comprises one or more transductors (1) comprising a bottom electrode (2), a charged triboelectric friction element (3) placed over the bottom electrode (2), and at least one top electrode (4) smaller than the bottom electrode (2) and placed over the triboelectric friction element (3) and defining at least one gap (5) on the friction element (3) of non- overlapping area with respect to the bottom electrode (2), exposing the triboelectric friction element (3) to the external environment so that contacting with a finger or solid varies instantaneously the capacitance of the transductor (1) generating an electrical signal containing physicochemical information of the solid in contact with the device readout by an acquisition and analysis module (7) which comprises at least of a resistive load.
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Abanades García, Juan Carlos
Arias Rozada, Borja
Fernández García, José Ramón
Abrégé
This invention discloses a calcination process to produce high purity CO2 from solids containing CaCO3 which operates cyclically and continuously on the solids, arranged in a packed or a moving bed, and wherein each cycle comprises a first step where the combustion at atmospheric pressure of a fuel in the bed of solids containing CaCO3 heats them up to 800-900° C. and a second step wherein a vacuum pressure between 0.05 and 0.5 atm is applied to extract pure CO2 from the solids containing CaCO3 while cooling them by 30-200° C. Said combustion can be carried out directly with air, oxygen enriched air or O2/CO2 mixtures when the process is applied to the calcination of a continuous flow of limestone in a moving bed shaft kiln. The process is also applied to calcine CaCO3 formed in reversible calcium looping processes comprising a carbonation reaction step to form CaCO3 from CaO.
B01D 53/96 - Régénération, réactivation ou recyclage des réactifs
C01B 3/16 - Production d'hydrogène ou de mélanges gazeux contenant de l'hydrogène par réaction de composés inorganiques comportant un hydrogène lié électropositivement, p. ex. de l'eau, des acides, des bases, de l'ammoniac, avec des agents réducteurs inorganiques par réaction de la vapeur d'eau avec l'oxyde de carbone avec des catalyseurs
C01B 3/40 - Production d'hydrogène ou de mélanges gazeux contenant de l'hydrogène par réaction de composés organiques gazeux ou liquides avec des agents gazéifiants, p. ex. de l'eau, du gaz carbonique, de l'air par réaction d'hydrocarbures avec des agents gazéifiants avec des catalyseurs caractérisée par le catalyseur
FUNDACIÓ INSTITUT CATALÀ DE NANOCIÈNCIA I NANOTECNOLOGIA (ICN2) (Espagne)
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (Espagne)
Inventeur(s)
Suárez García, Salvio
Saiz Poseu, Javier
Ruiz Molina, Daniel
Abrégé
The present invention provides a process for preparing a self-standing catecholamine-based membrane, the process comprising the steps of: (a) cross-linking a catechol derivative with an amine selected from the group consisting of: a known aliphatic amine hydrocarbon of formula (II); and an aromatic amine of formula (IIbis), in a liquid medium, wherein both the catechol and the amine are soluble, at a pH comprised from 6.5 to 10, and under appropriate agitation to create a catecholamine membrane in the air/liquid interface in the absence of any support; and b) isolating the membrane resulting from step (a) from the air/liquid interface. The resulting self-standing catecholamine-based membrane was robust, easy to handle and manipulate, highly flexible and adaptable to any kind of surface without breaking, and adhesive. In addition, the free-standing membrane of the invention shows a Janus character, with an unexpected nanopatterning in the water-contact side which endows the membranes of the invention with a higher roughness surface, something of value to promote cell adhesion.
The present invention provides a process for preparing a self-standing catecholamine-based membrane, the process comprising the steps of: (a) cross-linking a catechol derivative with an amine selected from the group consisting of: a known aliphatic amine hydrocarbon of formula (II); and an aromatic amine of formula (IIbis), in a liquid medium, wherein both the catechol and the amine are soluble, at a pH comprised from 6.5 to 10, and under appropriate agitation to create a catecholamine membrane in the air/liquid interface in the absence of any support; and b) isolating the membrane resulting from step (a) from the air/liquid interface. The resulting self-standing catecholamine-based membrane was robust, easy to handle and manipulate, highly flexible and adaptable to any kind of surface without breaking, and adhesive. In addition, the free-standing membrane of the invention shows a Janus character, with an unexpected nanopatterning in the water-contact side which endows the membranes of the invention with a higher roughness surface, something of value to promote cell adhesion.
A61L 24/00 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie
A61L 24/04 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie contenant des matériaux macromoléculaires
A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
A61L 27/58 - Matériaux au moins partiellement résorbables par le corps
C08G 65/40 - Composés macromoléculaires obtenus par des réactions créant une liaison éther dans la chaîne principale de la macromolécule à partir de composés hydroxylés ou de leurs dérivés métalliques dérivés des phénols à partir des phénols et d'autres composés
C08G 65/48 - Polymères modifiés par post-traitement chimique
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (Espagne)
Inventeur(s)
Aranda Regules, Miguel A.
Bretó Monfort, M Pau
Ruiz Ramón, Fabiola
Rodriguez Sepúlveda, Pascual
Donaire Segarra, Livia
Abrégé
The present invention relates to plants comprising in their genome a gene that has been inactivated rendering the plant resistant to Pepino mosaic virus (PepMV) infection. The present invention also refers to the inactivation of the gene required for PepMV infection. The invention encompasses parts of these plants and their progeny that show said gene inactivation and as a consequence an improved phenotype in terms of PepMV infection resistance. Methods for obtaining plants, or plant parts or seeds with resistance to PepMV infection are also part of this invention. The present invention further relates to the gene and sequences linked to it as markers for selecting plants resistant to PepMV infection. Therefore, the present invention belongs to the field of agriculture.
A01H 1/06 - Procédés de mutation, p. ex. traitements par produits chimiques ou irradiations
A01H 6/82 - Solanaceae, p. ex. poivron, tabac, pomme de terre, tomate ou aubergine
C12Q 1/6895 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les plantes, les champignons ou les algues
97.
IMMOBILIZED SELENIUM IN A POROUS CARBON WITH THE PRESENCE OF OXYGEN, A METHOD OF MAKING, AND USES OF IMMOBILIZED SELENIUM IN A RECHARGEABLE BATTERY
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (Espagne)
Inventeur(s)
Xu, Wen-Qing
Li, Xiaoming
Patkar, Shailesh
Eissler, Elgin E.
Solis, Marta Sevilla
Arias, Antonio Benito Fuertes
Abrégé
In a method of preparing an immobilized selenium system or body, a selenium-carbon-oxygen mixture is formed. The mixture is then heated to a temperature above the melting temperature of selenium and the heated mixture is then cooled to ambient or room temperature, thereby forming the immobilized selenium system or body.
H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
H01M 4/587 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
98.
CATALYST CONTAINING RUTHENIUM-OXO-CARBONATE AS AN ACTIVE PHASE FOR THE HYDROGENATION OF CO2 TO FORM METHANE AT LOW REACTION TEMPERATURES
C07C 1/12 - Préparation d'hydrocarbures à partir d'un ou plusieurs composés, aucun d'eux n'étant un hydrocarbure à partir d'oxydes de carbone à partir d'anhydride carbonique avec de l'hydrogène
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (Espagne)
UNIVERSITAT DE VALÈNCIA (Espagne)
Inventeur(s)
Mercader Badia, Josep Vicent
Abad Fuentes, Antonio
Abad Somovilla, Antonio
Agulló Blanes, Consuelo
Abrégé
The invention relates to compounds, in particular conjugates and labelled derivatives of zearalenone at a new position in the molecule, suitable for the production of antibodies with a high affinity for zearalenone. The invention also relates to the use of said zearalenone conjugates and labelled derivatives of zearalenone as test antigens. The invention also relates to the use of the compounds for the analysis, concentration and extraction of zearalenone using the obtained antibodies, sometimes together with test antigens that are conjugates or labelled derivatives. The invention also provides a kit for analysing zearalenone comprising antibodies against said mycotoxin, sometimes together with test antigens that are conjugates or labelled derivatives of zearalenone.
C07D 313/00 - Composés hétérocycliques contenant des cycles de plus de six chaînons comportant un atome d'oxygène comme unique hétéro-atome du cycle
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/532 - Production de composés immunochimiques marqués
C07K 16/14 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de champignons, d'algues ou de lichens
B01D 15/38 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction spécifique non couverte par un ou plusieurs des groupes , p. ex. chromatographie d'affinité, chromatographie d'échange par ligand ou chromatographie chirale
100.
Cryocooler Suitable for Gas Liquefaction Applications, Gas Liquefaction System and Method Comprising the Same
Consejo Superior de Investigaciones Cientificas (CSIC) (Espagne)
Universidad de Zaragoza (Espagne)
Inventeur(s)
Sese Monclus, Javier
Rillo Millan, Conrado
Abrégé
The present invention relates to a cryocooler suitable for gas liquefaction applications, that comprises a coldhead with one or more refrigeration stages; further comprising: a refrigerator compressor for distributing compressed gas-phase cryogen inside the coldhead; a heat exchanging coil arranged at least partially around the external region of the coldhead; at least one extraction orifice communicating a gas circulation circuit inside the coldhead with the heat exchanging coil; acting said extraction orifice/s as pass-through port/s which allow the gas inside the coldhead to flow through the inside of the heat exchanger coil for exchanging heat with the exterior thereof, and wherein the heat exchanging coil is adapted to connect and redirect the gas to one return port connected to the gas circulation circuit. Another object of the invention relates to a cryogen-gas liquefaction system and a method for liquefaction of gases that comprises said system.
F25J 1/02 - Procédés ou appareils de liquéfaction ou de solidification des gaz ou des mélanges gazeux nécessitant l'emploi d'une réfrigération, p. ex. de l'hélium, de l'hydrogène
F25B 9/10 - Machines, installations ou systèmes à compression dans lesquels le fluide frigorigène est l'air ou un autre gaz à point d'ébullition peu élevé avec plusieurs étages de refroidissement
F25J 1/00 - Procédés ou appareils de liquéfaction ou de solidification des gaz ou des mélanges gazeux