05 - Produits pharmaceutiques, vétérinaires et hygièniques
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical preparations for the treatment of bone disorders; Pharmaceutical preparations for the treatment of skeletal disorders; Pharmaceutical preparations for the treatment of muscular disorders; Pharmaceutical preparations for the treatment of ocular disorders; Pharmaceutical preparations for the treatment of tumors Providing medical information; Providing information to patients in the field of administering medications; Providing information relating to diagnostic, prophylactic and therapeutic properties of pharmaceuticals; Providing medical information in the field of pharmaceuticals
The invention features dosing regimens and pharmaceutical formulations for oral administration of palovarotene. The dosing regimens can reduce heterotopic ossification, reduce the number of flare-ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.
The invention features dosing regimens and pharmaceutical formulations for oral administration of palovarotene. The dosing regimens can reduce heterotopic ossification, reduce the number of flare-ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.
The invention features dosing regimens and pharmaceutical formulations for oral administration of palovarotene. The dosing regimens can reduce heterotopic ossification, reduce the number of flare-ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Business administration services relating to patient pharmaceutical reimbursement programs; business services, namely, administering a patient support and assistance program for obtaining reimbursement for prescription medicines. Providing educational information in the field of healthcare, medicine and therapeutic properties of pharmaceuticals. Providing medical and scientific research information in the field of pharmaceuticals. Providing medical information in the field of healthcare, medicine and therapeutic properties of pharmaceuticals.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Business administration services relating to patient pharmaceutical reimbursement programs; business services, namely, administering a patient support and assistance program for obtaining reimbursement for prescription medicines. Providing educational information in the field of healthcare, medicine and therapeutic properties of pharmaceuticals. Providing medical and scientific research information in the field of pharmaceuticals. Providing medical information in the field of healthcare, medicine and therapeutic properties of pharmaceuticals.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Business administration of patient pharmaceutical reimbursement programs; business services, namely, administering a patient support and assistance program for obtaining reimbursement for prescription medicines.
(2) Providing educational information in the field of healthcare, namely, relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment, medicine and therapeutic properties of pharmaceuticals.
(3) Providing medical and scientific research information in the field of pharmaceuticals.
(4) Information services in the field of medical treatment services, medical care and analysis services, and therapeutic properties of pharmaceuticals.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Business administration of patient pharmaceutical reimbursement programs; business services, namely, administering a patient support and assistance program for obtaining reimbursement for prescription medicines.
(2) Providing educational information in the field of healthcare, namely, relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment, medicine and therapeutic properties of pharmaceuticals.
(3) Providing medical and scientific research information in the field of pharmaceuticals.
(4) Information services in the field of medical treatment services, medical care and analysis services, and therapeutic properties of pharmaceuticals.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Maintaining a registry of patient data and medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; conducting business and market research surveys in the fields of pharmaceuticals and clinical trials. Providing a website featuring educational information in the fields of pharmaceuticals and clinical trials. Providing medical and scientific research information in the field of Fibrodysplasia ossificans progressiva (FOP) disease and treatment. Providing an online computer database featuring a registry of medical information and patient records; medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; medical services, namely providing support in the observation, monitoring, adherence and medical treatments on patients; Health assessment services, namely, health-related surveys and questionnaires that produce treatment information; conducting medical information surveys and questionnaires in the fields of disease and treatment, namely, conducting health surveys of patients with Fibrodysplasia ossificans progressiva (FOP) disease for medical purposes.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Maintaining a registry of patient data and medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; conducting business and market research surveys in the fields of pharmaceuticals and clinical trials. Providing a website featuring educational information in the fields of pharmaceuticals and clinical trials. Providing medical and scientific research information in the field of Fibrodysplasia ossificans progressiva (FOP) disease and treatment. Providing an online computer database featuring a registry of medical information and patient records; medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; medical services, namely providing support in the observation, monitoring, adherence and medical treatments on patients; Health assessment services, namely, health-related surveys and questionnaires that produce treatment information; conducting medical information surveys and questionnaires in the fields of disease and treatment, namely, conducting health surveys of patients with Fibrodysplasia ossificans progressiva (FOP) disease for medical purposes.
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Maintaining a registry of patient data and medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; conducting business and market research surveys in the fields of pharmaceuticals and clinical trials Providing a website featuring medical and scientific research educational information in the fields of pharmaceuticals and clinical trials; providing medical and scientific research information in the field of Fibrodysplasia ossificans progressiva (FOP) disease and treatment Providing an online computer database featuring a compilation of medical information and patient records being medical information; medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; medical assistance services, namely, providing support in the observation, monitoring, adherence and medical treatments on patients; health assessment services, namely, conducting health-related surveys and questionnaires that produce medical treatment information; conducting medical information surveys and questionnaires in the fields of disease and treatment, namely, conducting health surveys of patients with Fibrodysplasia ossificans progressiva (FOP) disease for medical purposes
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Maintaining a registry of patient data and medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; conducting business and market research surveys in the fields of pharmaceuticals and clinical trials Providing a website featuring medical and scientific research educational information in the fields of pharmaceuticals and clinical trials; providing medical and scientific research information in the field of Fibrodysplasia ossificans progressiva (FOP) disease and treatment Providing an online computer database featuring a compilation of medical information and patient records being medical information; medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; medical assistance services, namely, providing support in the observation, monitoring, adherence and medical treatments on patients; health assessment services, namely, conducting health-related surveys and questionnaires that produce medical treatment information; conducting medical information surveys and questionnaires in the fields of disease and treatment, namely, conducting health surveys of patients with Fibrodysplasia ossificans progressiva (FOP) disease for medical purposes
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Maintaining a registry of patient data and medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; conducting business and market research surveys in the fields of pharmaceuticals and clinical trials Providing a website featuring medical and scientific educational information in the fields of pharmaceuticals and clinical trials; providing medical and scientific research information in the field of Fibrodysplasia ossificans progressiva (FOP) disease and treatment Providing an online computer database featuring a compilation of medical information and patient records being medical information; medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; medical assistance services, namely, providing support in the observation, monitoring, adherence and medical treatments on patients; health assessment services, namely, conducting health-related surveys and questionnaires that produce medical treatment information; conducting medical information surveys and questionnaires in the fields of disease and treatment, namely, conducting health surveys of patients with Fibrodysplasia ossificans progressiva (FOP) disease for medical purposes
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Maintaining a registry of patient data and medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; conducting business and market research surveys in the fields of pharmaceuticals and clinical trials.
(2) Providing a website featuring educational information in the fields of pharmaceuticals and clinical trials; providing medical and scientific research information in the field of Fibrodysplasia ossificans progressiva (FOP) disease and treatment.
(3) Providing an online computer database featuring a registry of medical information and patient records; medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; medical services, namely providing support in the observation, monitoring, adherence and medical treatments on patients; Health assessment services, namely, health-related surveys and questionnaires that produce treatment information; conducting medical information surveys and questionnaires in the fields of disease and treatment, namely, conducting health surveys of patients with Fibrodysplasia ossificans progressiva (FOP) disease for medical purposes.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Maintaining a registry of patient data and medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; conducting business and market research surveys in the fields of pharmaceuticals and clinical trials.
(2) Providing a website featuring educational information in the fields of pharmaceuticals and clinical trials; providing medical and scientific research information in the field of Fibrodysplasia ossificans progressiva (FOP) disease and treatment.
(3) Providing an online computer database featuring a registry of medical information and patient records; medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; medical services, namely providing support in the observation, monitoring, adherence and medical treatments on patients; Health assessment services, namely, health-related surveys and questionnaires that produce treatment information; conducting medical information surveys and questionnaires in the fields of disease and treatment, namely, conducting health surveys of patients with Fibrodysplasia ossificans progressiva (FOP) disease for medical purposes.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Maintaining a registry of patient data and medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; conducting business and market research surveys in the fields of pharmaceuticals and clinical trials.
(2) Providing a website featuring educational information in the fields of pharmaceuticals and clinical trials; providing medical and scientific research information in the field of Fibrodysplasia ossificans progressiva (FOP) disease and treatment.
(3) Providing an online computer database featuring a registry of medical information and patient records; medical information relating to Fibrodysplasia ossificans progressiva (FOP) disease and treatment; medical services, namely providing support in the observation, monitoring, adherence and medical treatments on patients; Health assessment services, namely, health-related surveys and questionnaires that produce treatment information; conducting medical information surveys and questionnaires in the fields of disease and treatment, namely, conducting health surveys of patients with Fibrodysplasia ossificans progressiva (FOP) disease for medical purposes.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases or disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases and disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases and disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for use in the prevention and the treatment of cancer, orphan diseases, immune disorders, liver diseases, biliary diseases, metabolic diseases, inflammatory diseases, urological diseases, disorders and diseases of the reproductive system, puberty diseases and disorders, gynecological disorders, fertility, acromegalia and tumors, hormonal disorders, endocrine disorders, connective tissue diseases, blood diseases, gastrointestinal diseases and disorders, hemophilia, gastrointestinal bleeding disorders, neurological diseases, muscle disorders, bone disorders, skeletal disorders, neuromuscular disorders, cervical dystonia, cerebral palsy, spasticity, blepharospasm, migraine, bladder pain syndrome, pain, glabellar lines, facial wrinkles, asymmetries and defects and conditions of the human skin; pharmaceutical preparations containing botulinum toxin, botulinum toxin-haemagglutinin complex, botulinum toxin fragments and other botulinum toxin derivatives for skin care and the treatment of neurological disorders; pharmaceutical preparations containing botulinum toxin with specified component of the toxin haemagglutinin complex for skin care and the treatment of neurological disorders.
The invention describes dosing regimens for treating subjects with fibrodysplasia ossificans progressiva characterized by a quiescent period and a non-quiescent period, wherein a therapeutically effective amount of palovarotene is administered to the subjects during the non-quiescent period, little or no palovarotene is administered to the subjects during the quiescent period, and imatinib is administered to the subjects during the quiescent period and optionally during the non-quiescent period. The dosing regimens can reduce heterotopic ossification, reduce the number of flare-ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
A61P 19/08 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p. ex. rachitisme, maladie de Paget
41 - Éducation, divertissements, activités sportives et culturelles
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Brochures, newsletters, pamphlets relating to disease
conditions and treatment. Educational services in the nature of providing healthcare
information regarding diseases and treatment of diseases to
patients and healthcare professionals. Providing a website to patients and healthcare professionals
containing healthcare information regarding diseases and
treatment of diseases.
The invention features dosing regimens and pharmaceutical formulations for oral administration of palovarotene. The dosing regimens can reduce heterotopic ossification, reduce the number of flare-ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.
41 - Éducation, divertissements, activités sportives et culturelles
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Brochures, newsletters, pamphlets relating to disease conditions and treatment. (1) Educational services in the nature of providing healthcare information regarding diseases and treatment of diseases to patients and healthcare professionals, namely, bone disorders, skeletal disorders, muscular disorders, ocular disorders and tumors.
(2) Providing a website to patients and healthcare professionals containing healthcare information regarding diseases and treatment of diseases, namely, bone disorders, skeletal disorders, muscular disorders, ocular disorders and tumors.
41 - Éducation, divertissements, activités sportives et culturelles
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Brochures, newsletters, pamphlets relating to disease conditions and treatment. Educational services in the nature of providing healthcare information regarding diseases and treatment of diseases to patients and healthcare professionals. Providing a website to patients and healthcare professionals containing healthcare information regarding diseases and treatment of diseases.
09 - Appareils et instruments scientifiques et électriques
16 - Papier, carton et produits en ces matières
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Downloadable electronic publications in the nature of brochures, newsletters and pamphlets in the field of disease conditions and treatment Printed brochures, newsletters, and pamphlets in the field of disease conditions and treatment Providing a website to patients and healthcare professionals containing healthcare information regarding diseases and treatment of diseases; Educational services in the nature of providing healthcare information regarding diseases and treatment of diseases to patients and healthcare professionals
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for the treatment of bone disorders, musculoskeletal disorders in the nature of connective tissue diseases, bone diseases, spinal diseases, back pain, fractures, sprains, cartilage injuries, inflammatory muscular disorders, ocular disorders, and for treatment of malignant, benign, and precancerous tumors
The invention describes dosing regimens for treating subjects with fibrodysplasia ossificans progressiva characterized by a quiescent period and a non-quiescent period, wherein a therapeutically effective amount of palovarotene is administered to the subjects during the non-quiescent period, little or no palovarotene is administered to the subjects during the quiescent period, and imatinib is administered to the subjects during the quiescent period and optionally during the non-quiescent period. The dosing regimens can reduce heterotopic ossification, reduce the number of flare- ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.
A61P 19/08 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p. ex. rachitisme, maladie de Paget
C07D 231/12 - Composés hétérocycliques contenant des cycles diazole-1, 2 ou diazole-1, 2 hydrogéné non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle
C07D 401/04 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
The invention describes dosing regimens for treating subjects with fibrodysplasia ossificans progressiva characterized by a quiescent period and a non-quiescent period, wherein a therapeutically effective amount of palovarotene is administered to the subjects during the non- quiescent period, little or no palovarotene is administered to the subjects during the quiescent period, and imatinib is administered to the subjects during the quiescent period and optionally during the non-quiescent period. The dosing regimens can reduce heterotopic ossification, reduce the number of flare- ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.
A61P 19/08 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p. ex. rachitisme, maladie de Paget
C07D 231/12 - Composés hétérocycliques contenant des cycles diazole-1, 2 ou diazole-1, 2 hydrogéné non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle
C07D 401/04 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of bone disorders; pharmaceutical preparations for the treatment of the musculoskeletal system, namely, connective tissue diseases, bone diseases, spinal diseases, back pain, fractures, sprains, cartilage injuries; pharmaceutical preparations for the treatment of inflammatory muscle diseases and disorders; pharmaceutical preparations for the treatment of ocular disorders; pharmaceutical preparations for the treatment of malignant, benign and precancerous tumors.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of bone disorders; pharmaceutical preparations for the treatment of the musculoskeletal system, namely, connective tissue diseases, bone diseases, spinal diseases, back pain, fractures, sprains, cartilage injuries; pharmaceutical preparations for the treatment of inflammatory muscle diseases and disorders; pharmaceutical preparations for the treatment of ocular disorders; pharmaceutical preparations for the treatment of malignant, benign and precancerous tumors.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for the treatment of bone
disorders; pharmaceutical preparations for the treatment of
skeletal disorders; pharmaceutical preparations for the
treatment of muscular disorders; pharmaceutical preparations
for the treatment of ocular disorders; pharmaceutical
preparations for the treatment of tumors.
The invention features methods for inhibiting the formation, reducing the size, and slowing the growth of an osteochondroma in a subject with multiple osteochondroma (MO) by administering to the subject palovarotene (also known as R667), or a pharmaceutically acceptable salt thereof. The methods described herein can also ameliorate complications associated with osteochondroma formation and growth in a subject with MO.
The invention features dosing regimens and pharmaceutical formulations for oral administration of palovarotene. The dosing regimens can reduce heterotopic ossification, reduce the number of flare-ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of bone disorders, skeletal disorders, muscular disorders, ocular disorders and for treatment of tumors.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of bone disorders, skeletal disorders, muscular disorders, ocular disorders and for treatment of tumors.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of bone disorders; pharmaceutical preparations for the treatment of the musculoskeletal system, namely, connective tissue diseases, bone diseases, spinal diseases, fractures, trauma and post-surgical injuries, cartilage injuries; pharmaceutical preparations for the treatment of inflammatory muscle diseases and disorders; pharmaceutical preparations for the treatment of ocular disorders; pharmaceutical preparations for the treatment of malignant, benign and precancerous tumors.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of bone disorders; pharmaceutical preparations for the treatment of the musculoskeletal system, namely, connective tissue diseases, bone diseases, spinal diseases, fractures, trauma and post-surgical injuries, cartilage injuries; pharmaceutical preparations for the treatment of inflammatory muscle diseases and disorders; pharmaceutical preparations for the treatment of ocular disorders; pharmaceutical preparations for the treatment of malignant, benign and precancerous tumors.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for the treatment of bone disorders; Pharmaceutical preparations for the treatment of skeletal disorders; Pharmaceutical preparations for the treatment of muscular disorders; Pharmaceutical preparations for the treatment of ocular disorders; Pharmaceutical preparations for the treatment of tumors.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Pharmaceutical preparations for the treatment of bone disorders; Pharmaceutical preparations for the treatment of skeletal disorders; Pharmaceutical preparations for the treatment of muscular disorders; Pharmaceutical preparations for the treatment of ocular disorders; Pharmaceutical preparations for the treatment of tumors.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of bone disorders; pharmaceutical preparations for the treatment of the musculoskeletal system, namely, connective tissue diseases, bone diseases, spinal diseases, fractures, trauma and post-surgical injuries, cartilage injuries; pharmaceutical preparations for the treatment of inflammatory muscle diseases and disorders; pharmaceutical preparations for the treatment of ocular disorders; pharmaceutical preparations for the treatment of malignant, benign and precancerous tumors.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of bone disorders; pharmaceutical preparations for the treatment of the musculoskeletal system, namely, connective tissue diseases, bone diseases, spinal diseases, fractures, trauma and post-surgical injuries, cartilage injuries; pharmaceutical preparations for the treatment of inflammatory muscle diseases and disorders; pharmaceutical preparations for the treatment of ocular disorders; pharmaceutical preparations for the treatment of malignant, benign and precancerous tumors.
The invention features methods for inhibiting the formation, reducing the size, and slowing the growth of an osteochondroma in a subject with multiple osteochondroma (MO) by administering to the subject palovarotene (also known as R667), or a pharmaceutically acceptable salt thereof. The methods described herein can also ameliorate complications associated with osteochondroma formation and growth in a subject with MO.
C07D 231/12 - Composés hétérocycliques contenant des cycles diazole-1, 2 ou diazole-1, 2 hydrogéné non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle
05 - Produits pharmaceutiques, vétérinaires et hygièniques
16 - Papier, carton et produits en ces matières
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Pharmaceutical preparations. Brochures, newsletters, pamphlets relating to disease conditions and treatment. Providing a website to patients and healthcare professionals containing healthcare information regarding diseases and treatment of diseases.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of bone disorders; pharmaceutical preparations for the treatment of the musculoskeletal system, namely, connective tissue diseases, bone diseases, spinal diseases, back pain, fractures, sprains, cartilage injuries; pharmaceutical preparations for the treatment of inflammatory muscle diseases and disorders; pharmaceutical preparations for the treatment of ocular disorders; pharmaceutical preparations for the treatment of tumors.
The invention features dosing regimens and pharmaceutical formulations for oral administration of palovarotene. The dosing regimens can reduce heterotopic ossification, reduce the number of flare- ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.
C07D 231/12 - Composés hétérocycliques contenant des cycles diazole-1, 2 ou diazole-1, 2 hydrogéné non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle
The invention features dosing regimens and pharmaceutical formulations for oral administration of palovarotene. The dosing regimens can reduce heterotopic ossification, reduce the number of flare- ups, and/or reduce the severity of flare-ups in subjects suffering from fibrodysplasia ossificans progressiva.
C07D 231/12 - Composés hétérocycliques contenant des cycles diazole-1, 2 ou diazole-1, 2 hydrogéné non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle