Produits et services

Providing a website featuring blogs and non-downloadable publications in the nature of articles, newsletters, and blog posts in the field(s) of dietary supplements, nutritional supplements, pharmaceuticals, medicine, intravenous fluids, immunology, virology, cosmetics, non-medicated toiletry preparations, pet products, personal care products, food, beverages, fitness, exercise, workouts, wellness, lifestyle, health, nutrition, nicotinamide adenine dinucleotide, nicotinamide riboside chloride, cellular energy and repair, stress management, longevity, and healthy aging; Providing information on physical exercise; Education services, namely, providing training, seminars, and instruction in the field of dietary supplements, nutritional supplements, pharmaceuticals, medicine, intravenous fluids, immunology, virology, cosmetics, non-medicated toiletry preparations, pet products, personal care products, food, beverages, fitness, exercise, workouts, wellness, lifestyle, health, nutrition, nicotinamide adenine dinucleotide, nicotinamide riboside chloride, cellular energy and repair, stress management, longevity, and healthy aging Medical and scientific research information in the field of dietary supplements, nutritional supplements, pharmaceuticals, medicine, intravenous fluids, immunology, virology, cosmetics, non-medicated toiletry preparations, pet products, personal care products, food, beverages, fitness, exercise, workouts, wellness, lifestyle, health, nutrition, nicotinamide adenine dinucleotide, nicotinamide riboside chloride, cellular energy and repair, stress management, longevity, and healthy aging; Providing scientific research information in the field of dietary supplements, nutritional supplements, pharmaceuticals, medicine, intravenous fluids, immunology, virology, cosmetics, non-medicated toiletry preparations, pet products, personal care products, food, beverages, fitness, exercise, workouts, wellness, lifestyle, health, nutrition, nicotinamide adenine dinucleotide, nicotinamide riboside chloride, cellular energy and repair, stress management, longevity, and healthy aging; Providing medical and scientific research information in the field of clinical trials; Providing information in the field of clinical research via a website; Scientific research and development; Medical research; Product research and development; Providing scientific information in the field of dietary supplements, nutritional supplements, pharmaceuticals, medicine, intravenous fluids, immunology, virology, cosmetics, non-medicated toiletry preparations, pet products, personal care products, food, beverages, fitness, exercise, workouts, wellness, lifestyle, health, nutrition, nicotinamide adenine dinucleotide, nicotinamide riboside chloride, cellular energy and repair, stress management, longevity, and healthy aging; Innovation consulting services, namely, advising others in the areas of product development; Product development consulting in the field of dietary supplements, nutritional supplements, pharmaceuticals, medicine, intravenous fluids, immunology, virology, cosmetics, non-medicated toiletry preparations, pet products, personal care products, food, beverages, fitness, exercise, workouts, wellness, lifestyle, health, nutrition, nicotinamide adenine dinucleotide, nicotinamide riboside chloride, cellular energy and repair, stress management, longevity, and healthy aging; Scientific research consulting in the field of dietary supplements, nutritional supplements, pharmaceuticals, medicine, intravenous fluids, immunology, virology, cosmetics, non-medicated toiletry preparations, pet products, personal care products, food, beverages, fitness, exercise, workouts, wellness, lifestyle, health, nutrition, nicotinamide adenine dinucleotide, nicotinamide riboside chloride, cellular energy and repair, stress management, longevity, and healthy aging; Chemical, biochemical, biological and bacteriological research and analysis; Pharmaceutical research and development; Scientific and technological services, namely, testing, inspection, research, and development in the field of dietary supplements, nutritional supplements, pharmaceuticals, medicine, intravenous fluids, immunology, virology, cosmetics, cosmetic preparations, non-medicated toiletry preparations, pet products, personal care products, food, beverages, wellness, lifestyle, health, nutrition, nicotinamide adenine dinucleotide, nicotinamide riboside chloride, brain health, muscle health and recovery, immune health, heart health, cellular energy and repair, stress management, and healthy aging; Scientific research consulting; Research and development and consultation related thereto in the field of dietary supplements, nutritional supplements, pharmaceuticals, medicine, intravenous fluids, immunology, virology, cosmetics, non-medicated toiletry preparations, pet products, personal care products, food, beverages, fitness, exercise, workouts, wellness, lifestyle, health, nutrition, nicotinamide adenine dinucleotide, nicotinamide riboside chloride, cellular energy and repair, stress management, longevity, and healthy aging; Consulting services for others in the field of design, planning, and implementation project management of scientific research and clinical trials Providing information and advice in the field of pet health; Providing information in the fields of health and wellness; Providing information in the fields of health and wellness in the field of dietary supplements, nutritional supplements, pharmaceuticals, medicine, intravenous fluids, immunology, virology, cosmetics, non-medicated toiletry preparations, pet products, personal care products, food, beverages, fitness, exercise, workouts, lifestyle, nutrition, nicotinamide adenine dinucleotide, nicotinamide riboside chloride, cellular energy and repair, stress management, longevity, and healthy aging via a website; Providing information about dietary supplements and nutrition; Providing health information; Providing information about beauty; Providing beauty care information; Providing news and information in the field of personal beauty

Produits et services

Active chemical ingredients for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals, cosmetics, cosmetic preparations, pet products, and personal care products; chemical reagents for non-medical purposes; chemicals for use in industry and science; chemicals for use in the biochemical and chemical industry; assays for research purposes; diagnostic preparations for scientific or research use; test kits comprised of chemical preparations and reagents for testing biomarkers and levels of nicotinamide adenine dinucleotide, vitamins, metabolites, and enzymes for scientific purposes, other than for medical or veterinary use; test kits comprised of chemical agents and chemical preparations for testing biomarkers and levels of nicotinamide adenine dinucleotide, vitamins, metabolites, and enzymes for scientific purposes, other than for medical or veterinary use; specimen collection kits comprised primarily of chemically treated non-medical test strips and cards and also including, laboratory swabs, plastic bags for transmitting specimens, printed mailing labels, and tubes for holding specimens for scientific purposes, other than for medical or veterinary use; test kits for testing for markers in bodily fluids, liquids, saliva and tissue for non-medical purposes; chemical preparations and articles, namely, chemical test paper, strips, and cards for the testing of nicotinamide adenine dinucleotide levels, cellular energy, brain health, muscle health and recovery, immune health, heart health, cellular energy and repair, stress management, and healthy aging for scientific purposes, other than for medical or veterinary use. Pharmaceutical preparations, namely, nicotinamide riboside chloride for injection; pharmaceutical preparations, namely, injectable liquids for use in hydration, vitamin, healthy aging, and wellness therapies; pharmaceutical preparations, namely, injectable liquids for increasing health, healthy aging, cellular health, cellular repair, energy, heart health, and muscle health; pharmaceutical preparations and nutritional supplements, namely, nicotinamide riboside chloride in the form of injectables; pharmaceutical preparations and nutritional supplements, namely, nicotinamide riboside chloride for use in intravenous therapy; diagnostic kits comprised of medical diagnostic assays for testing for biomarkers and levels of nicotinamide adenine dinucleotide, vitamins, metabolites, and enzymes for medical purposes; diagnostic kits for testing biomarkers and levels of nicotinamide adenine dinucleotide, vitamins, metabolites, and enzymes for medical purposes; diagnostic kits comprising diagnostic agents and preparations for medical purposes; specimen collection kits for medical purposes comprised primarily of swabs for medical purposes and also including test strips, plastic bags for transmitting medical specimens, printed mailing labels, and tubes for holding specimens; medical test kits comprised primarily of swabs, testing strips and cards for medical purposes, and also including lancets, adhesive bandages, plastic bags for transmitting medical specimens, and printed mailing labels for testing for markers in bodily fluids, liquids, saliva and tissue; diagnostic agents, preparations and substances for medical purposes; medical and veterinary diagnostic preparations and articles, namely, swabs, testing strips and cards for medical purposes for the testing of nicotinamide adenine dinucleotide levels, cellular energy, brain health, muscle health and recovery, immune health, heart health, cellular energy and repair, stress management, and healthy aging; diagnostic preparations and articles, namely, supplements, pharmaceutical preparations, and intravenous fluids for promoting nicotinamide adenine dinucleotide levels, cellular energy, brain health, muscle health and recovery, immune health, heart health, cellular energy and repair, stress management, and healthy aging for medical and veterinary use; prefilled syringes and medical fluid injectors sold filled with pharmaceutical preparations; prefilled syringes and injectors filled with pharmaceutical preparations, namely, nicotinamide adenine dinucleotide precursors for promoting nicotinamide adenine dinucleotide levels, cellular energy, brain health, muscle health and recovery, immune health, heart health, cellular energy and repair, stress management, and healthy aging; prefilled syringes and medical fluid injectors sold filled with nicotinamide riboside chloride; nutritional supplements in the form of an injection shot; pharmaceutical preparations and nutritional supplements, namely, nicotinamide riboside chloride in the form of an injection shot.

Abrégé

A stable intravenous (I.V.) composition includes nicotinamide riboside (NR) as described, or other nicotinyl riboside compounds which are NAD+ precursors, in said intravenous form. NR chloride may be provided in an intravenous (I.V.) formulation for administration to a human subject.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 31/7084 - Composés ayant deux nucléosides ou nucléotides, p. ex. dinucléotide de la nicotinamide-adénine, dinucléotide de la flavine-adénine

Abrégé

The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): wherein X−, Z1, Z2, n, R1, R2, R3, R4, R5, R6, R7, and R8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof, and novel crystalline forms thereof.

Classes IPC  ?

• C07H 19/048 - Radicaux pyridine
• C07D 307/20 - Atomes d'oxygène
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle
• C07H 19/20 - Radicaux purine avec le radical saccharide estérifié par des acides phosphoriques ou polyphosphoriques

Produits et services

Dietary supplements; Nutritional supplements; Dietary supplements for health, cellular energy, cellular health, cellular repair, brain health, muscle health and recovery, immune health, heart health, stress management, and healthy aging; Nutritional supplements for health, cellular energy, cellular health, cellular repair, brain health, muscle health and recovery, immune health, heart health, stress management, and healthy aging

Abrégé

A stable intravenous (I.V.) composition includes nicotinamide riboside (NR) as described, or other nicotinyl riboside compounds which are NAD+ precursors, in said intravenous form. NR chloride may be provided in an intravenous (I.V.) formulation for administration to a human subject.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 31/7084 - Composés ayant deux nucléosides ou nucléotides, p. ex. dinucléotide de la nicotinamide-adénine, dinucléotide de la flavine-adénine

Abrégé

A stable intravenous (I.V.) composition includes nicotinamide riboside (NR) as described, or other nicotinyl riboside compounds which are NAD+ precursors, in said intravenous form. NR chloride may be provided in an intravenous (I.V.) formulation for administration to a human subject.

Classes IPC  ?

• A61K 31/395 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines
• A61K 31/7052 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier

Produits et services

Active Chemical ingredients for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals, cosmetics, cosmetic preparations, pet products, and personal care products; chemical reagents for non-medical purposes; chemicals for use in industry and science; chemicals for use in the biochemical and chemical industry; assays for research purposes; diagnostic preparations for scientific or research use; test kits comprised of chemical preparations and reagents for testing biomarkers and levels of nicotinamide adenine dinucleotide, vitamins, metabolites, and enzymes for scientific purposes, other than for medical or veterinary use; test kits comprised of chemical agents and chemical preparations for testing biomarkers and levels of nicotinamide adenine dinucleotide, vitamins, metabolites, and enzymes for scientific purposes, other than for medical or veterinary use; specimen collection kits comprised primarily of chemically treated non-medical test strips and cards and also including, laboratory swabs, plastic bags for transmitting specimens, printed mailing labels, and tubes for holding specimens for scientific purposes, other than for medical or veterinary use; test kits for testing for markers in bodily fluids, liquids, saliva and tissue for non-medical purposes; chemical preparations and articles, namely, chemical test paper, strips, and cards for the testing of nicotinamide adenine dinucleotide levels, cellular energy, brain health, muscle health and recovery, immune health, heart health, cellular energy and repair, stress management, and healthy aging for scientific purposes, other than for medical or veterinary use Pharmaceutical preparations, namely, nicotinamide riboside chloride for injection; pharmaceutical preparations, namely, injectable liquids for use in hydration, vitamin, healthy aging, and wellness therapies; pharmaceutical preparations, namely, injectable liquids for increasing health, healthy aging, cellular health, cellular repair, energy, heart health, and muscle health; pharmaceutical preparations and nutritional supplements, namely, nicotinamide riboside chloride in the form of injectables; pharmaceutical preparations and nutritional supplements, namely, nicotinamide riboside chloride for use in intravenous therapy; diagnostic kits comprised of medical diagnostic assays for testing for biomarkers and levels of nicotinamide adenine dinucleotide, vitamins, metabolites, and enzymes for medical purposes; diagnostic kits for testing biomarkers and levels of nicotinamide adenine dinucleotide, vitamins, metabolites, and enzymes for medical purposes; diagnostic kits comprising diagnostic agents and preparations for medical purposes; specimen collection kits for medical purposes comprised primarily of swabs for medical purposes and also including test strips, plastic bags for transmitting medical specimens, printed mailing labels, and tubes for holding specimens; medical test kits comprised primarily of swabs, testing strips and cards for medical purposes, and also including lancets, adhesive bandages, plastic bags for transmitting medical specimens, and printed mailing labels for testing for markers in bodily fluids, liquids, saliva and tissue; diagnostic agents, preparations and substances for medical purposes; medical and veterinary diagnostic preparations and articles, namely, swabs, testing strips and cards for medical purposes for the testing of nicotinamide adenine dinucleotide levels, cellular energy, brain health, muscle health and recovery, immune health, heart health, cellular energy and repair, stress management, and healthy aging; diagnostic preparations and articles, namely, supplements, pharmaceutical preparations, and intravenous fluids for promoting nicotinamide adenine dinucleotide levels, cellular energy, brain health, muscle health and recovery, immune health, heart health, cellular energy and repair, stress management, and healthy aging for medical and veterinary use; prefilled syringes and medical fluid injectors sold filled with pharmaceutical preparations; prefilled syringes and injectors filled with pharmaceutical preparations, namely, nicotinamide adenine dinucleotide precursors for promoting nicotinamide adenine dinucleotide levels, cellular energy, brain health, muscle health and recovery, immune health, heart health, cellular energy and repair, stress management, and healthy aging; prefilled syringes and medical fluid injectors sold filled with nicotinamide riboside chloride; nutritional supplements in the form of an injection shot; pharmaceutical preparations and nutritional supplements, namely, nicotinamide riboside chloride in the form of an injection shot

Produits et services

On-line retail store services featuring dietary supplements, nutritional supplements, cosmetics, cosmetic preparations, non-medicated toiletry preparations, pet products, personal care products, food, and beverages; Retail store services featuring dietary supplements, nutritional supplements, cosmetics, cosmetic preparations, non-medicated toiletry preparations, pet products, personal care products, food, and beverages

Produits et services

Cosmetics; cosmetic preparations; non-medicated toiletry preparations; chemicals sold as components of cosmetics and cosmetic preparations; nutritional supplements sold as a component of cosmetics and cosmetic preparations; body and beauty care cosmetics; cosmetic preparations for body care; cosmetic preparations for skin care; cosmetic preparations in the form of scrubs, lotions, oils, serums, toners, moisturizers, creams, gels, powders, aerosols, sprays, emulsions, pomades, and masks; cosmetic suntan preparations; non-medicated soaps; cosmetic preparations for bath and shower; hair care preparations; cosmetics for animals; make-up; make-up preparations; perfume; cologne; nail care preparations; nail polish

Produits et services

Cosmetics; cosmetic preparations; non-medicated toiletry preparations; chemicals sold as components of cosmetics and cosmetic preparations; nutritional supplements sold as a component of cosmetics and cosmetic preparations; body and beauty care cosmetics; cosmetic preparations for body care; cosmetic preparations for skin care; cosmetic preparations in the form of scrubs, lotions, oils, serums, toners, moisturizers, creams, gels, powders, aerosols, sprays, emulsions, pomades, and masks; non-medicated soaps; cosmetic preparations for bath and shower; hair care preparations; cosmetics for animals

Produits et services

Cosmetics; cosmetic preparations; non-medicated toiletry preparations; chemicals sold as components of cosmetics and cosmetic preparations; nutritional supplements sold as a component of cosmetics and cosmetic preparations; body and beauty care cosmetics; cosmetic preparations for body care; cosmetic preparations for skin care; cosmetic preparations in the form of scrubs, lotions, oils, serums, toners, moisturizers, creams, gels, powders, aerosols, sprays, emulsions, pomades, and masks; non-medicated soaps; cosmetic preparations for bath and shower; hair care preparations; cosmetics for animals

Produits et services

(1) Body and beauty care cosmetics; body emulsions for cosmetic purposes; body sprays for cosmetic purposes; cosmetic bath and shower gels; cosmetic body scrubs; cosmetic facial care preparations; cosmetic hair care preparations; cosmetic masks; cosmetic moisturizing skin gels; cosmetic nail care preparations; cosmetic oils; cosmetic powders, creams and lotions for the face, hands and body; cosmetic preparations for skin care; cosmetic serums for firming the skin; cosmetic soaps; cosmetic suntan preparations; cosmetics; facial serums for cosmetic purposes; hair care preparations; make-up; make-up preparations; pomades for cosmetic purposes; skin moisturizers used as cosmetics; toners for cosmetic use;

Produits et services

Cosmetics; cosmetic preparations; non-medicated toiletry preparations; chemicals sold as components of cosmetics and cosmetic preparations; nutritional supplements sold as a component of cosmetics and cosmetic preparations; body and beauty care cosmetics; cosmetic preparations for body care; cosmetic preparations for skin care; cosmetic preparations in the form of scrubs, lotions, oils, serums, toners, moisturizers, creams, gels, powders, aerosols, sprays, emulsions, pomades, and masks; cosmetic suntan preparations; cosmetic soaps; cosmetic preparations for bath and shower; hair care preparations; cosmetics for animals; make-up; make-up preparations; perfume; cologne; nail care preparations; nail polish

Abrégé

The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): 8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof, and novel crystalline forms thereof.

Classes IPC  ?

• C07H 19/048 - Radicaux pyridine
• C07D 307/20 - Atomes d'oxygène
• C07H 19/20 - Radicaux purine avec le radical saccharide estérifié par des acides phosphoriques ou polyphosphoriques
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle

Produits et services

Pharmaceutical preparations, namely, nicotinamide riboside for injection; pharmaceutical preparations, namely, injectable liquids for use in hydration, vitamin, healthy aging, and wellness therapies; pharmaceutical preparations, namely, injectable liquids for increasing health, healthy aging, cellular health, cellular repair, energy, heart health, and muscle health; nicotinamide riboside in the form of injectables; nicotinamide riboside for use in intravenous therapy; dietary supplements; nutritional supplements On-line retail store services featuring injectable intravenous solutions, dietary supplements, and nutritional supplements; retail store services featuring injectable intravenous solutions, dietary supplements, and nutritional supplements Intravenous therapy services; intravenous therapy services featuring nicotinamide riboside; providing information about health, healthy aging, lifestyle wellness, healthy eating, and nutrition

Abrégé

This disclosure relates to a process for producing Crystalline Beta Nicotinamide Riboside Triacetate Chloride with improved physical property characteristics. A substantially crystalline Beta Nicotinamide Riboside Triacetate Chloride, or a salt, or a solvate thereof is described having a chemical purity of greater than about 90% (w/w) and containing less than about 5000 ppm ethanol.

Classes IPC  ?

• C07H 19/048 - Radicaux pyridine
• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• C07H 1/00 - Procédés de préparation des dérivés du sucre

Abrégé

This disclosure relates to a process for producing Crystalline Beta Nicotinamide Riboside Triacetate Chloride with improved physical property characteristics. A substantially crystalline Beta Nicotinamide Riboside Triacetate Chloride, or a salt, or a solvate thereof is described having a chemical purity of greater than about 90% (w/w) and containing less than about 5000 ppm ethanol.

Classes IPC  ?

• C07H 19/048 - Radicaux pyridine

Produits et services

Active chemical ingredients for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals, cosmetics, cosmetic preparations, pet products, and personal care products; Chemical reagents for non-medical purposes; Chemicals for use in industry and science; Chemicals for use in the biochemical and chemical industry; Assays for research purposes; Diagnostic preparations for scientific or research use Cosmetics; cosmetic preparations; non-medicated toiletry preparations; chemicals sold as components of cosmetics and cosmetic preparations; nutritional supplements sold as a component of cosmetics and cosmetic preparations; cosmetic preparations; body and beauty care cosmetics; cosmetic preparations for body care; cosmetic preparations for skin care; cosmetic preparations in the form of scrubs, lotions, oils, serums, toners, moisturizers, creams, gels, powders, aerosols, sprays, emulsions, pomades, and masks; cosmetic suntan preparations; cosmetic soaps; cosmetic preparations for bath and shower; hair care preparations; cosmetics for animals; make-up; make-up preparations; perfume; cologne; nail care preparations; nail polish Dietary and nutritional supplements; diagnostic kits consisting primarily of monoclonal antibodies, buffers, and reagents for use in disease testing; diagnostic preparations for medical purposes; diagnostic agents, preparations and substances for medical purposes; dietary supplements and preparations; medical and veterinary preparations and articles for the treatment of declining nicotinamide adenine dinucleotide levels and cellular energy, and for the support of brain health, muscle health and recovery, immune health, heart health, cellular energy and repair, stress management, and healthy aging On-line retail store services featuring dietary supplements, nutritional supplements, cosmetics, cosmetic preparations, pet products, personal care products, food, and beverages; Retail store services featuring dietary supplements, nutritional supplements, cosmetics, cosmetic preparations, pet products, personal care products, food, and beverages Providing a website and non-downloadable publications in the nature of articles, newsletters, and blog posts in the field of health, fitness, exercise, workouts, wellness, lifestyle, cosmetics, pet products, personal care products, healthy eating, dietary and nutritional supplements, and nutrition; Providing information and reviews about physical fitness, exercise and fitness workouts Medical and scientific research information in the field of health, nutrition, dietary and nutritional supplements, cosmetics, pet products, personal care products, cellular energy, nicotinamide adenine dinucleotide, and nicotinamide riboside; Providing scientific information in the field of research regarding health, nutrition, dietary and nutritional supplements, cosmetics, pet products, personal care products, cellular energy, nicotinamide adenine dinucleotide, and nicotinamide riboside; Providing scientific research information in the field of clinical studies; Providing a website featuring educational information in the field of clinical research Providing information about health, lifestyle, wellness, cosmetics, personal care products, pet health and wellness products, healthy eating, dietary and nutritional supplements, and nutrition

Abrégé

Infant formula compositions and methods for delivering at least one compound selected from nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, in combination with at least one of thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), and pyridoxine (vitamin B6), to an infant human subject in need of said compound or compounds are provided.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 31/51 - Thiamines, p. ex. vitamine B1
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A61K 31/4415 - Pyridoxine, c.-à-d. vitamine B6
• A61K 31/455 - Acide nicotinique, c.-à-d. niacineSes dérivés, p. ex. esters, amides
• A61K 31/525 - Iso-alloxazines, p. ex. riboflavines, vitamine B2
• A61K 31/7064 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées
• A23L 33/19 - Protéines du lait
• A23L 33/00 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement
• A23L 33/15 - Vitamines
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine

Produits et services

Innovation consulting services, namely, advising others in the areas of product development; Product development consulting in the field of dietary supplements, nutritional products, pharmaceuticals, health, medicine, aging, immunology, virology, and cosmetics; Scientific research consulting in the field of dietary supplements, nutritional products, pharmaceuticals, health, medicine, aging, immunology, virology, and cosmetics; Scientific consulting and research services relating to foods and dietary supplements; Chemical, biochemical, biological and bacteriological research and analysis; Industrial research in the field of chemicals; Pharmaceutical research and development; Testing, inspection, research, or development of dietary supplements, nutritional products, pharmaceuticals, medicine, and cosmetics; Product research and development; Scientific research and development; Scientific research consulting; Medical research; Research and development and consultation related thereto in the field of dietary supplements, nutritional products, pharmaceuticals, health, medicine, aging, immunology, virology, cosmetics, chemicals, chemical standards, and chemical reference materials; Consulting services for others in the field of design, planning, and implementation project management of scientific research and clinical trials; Design and testing for new product development; Testing, inspection or research of pharmaceuticals, cosmetics or foodstuff.

Produits et services

Diagnostic kits consisting primarily of monoclonal antibodies, buffers, and reagents for use in disease testing; diagnostic preparations for medical purposes; diagnostic agents, preparations and substances for medical purposes; dietary preparations; medical and veterinary preparations and articles. Downloadable mobile applications for managing and sharing information on one's health, fitness and nutrition; downloadable software in the nature of a mobile application for providing information in the fields of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition; downloadable mobile application software for the purpose of tracking and monitoring health, wellness and nutrition; computer software for providing information in the fields of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition. Providing information about fitness, exercise, and workouts; on-line journals, namely, blogs featuring articles, information, reviews and recipes in the field of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition.

Produits et services

Innovation consulting services, namely, advising others in the areas of product development; Product development consulting in the field of dietary supplements, nutritional products, pharmaceuticals, health, medicine, aging, immunology, virology, and cosmetics; Scientific research consulting in the field of dietary supplements, nutritional products, pharmaceuticals, health, medicine, aging, immunology, virology, and cosmetics; Scientific consulting and research services relating to foods and dietary supplements; Chemical, biochemical, biological and bacteriological research and analysis; Industrial research in the field of chemicals; Pharmaceutical research and development; Testing, inspection, research, or development of dietary supplements, nutritional products, pharmaceuticals, medicine, and cosmetics; Product research and development; Scientific research and development; Scientific research consulting; Medical research; Research and development and consultation related thereto in the field of dietary supplements, nutritional products, pharmaceuticals, health, medicine, aging, immunology, virology, cosmetics, chemicals, chemical standards, and chemical reference materials; Consulting services for others in the field of design, planning, and implementation project management of scientific research and clinical trials; Design and testing for new product development; Testing, inspection or research of pharmaceuticals, cosmetics or foodstuff

Produits et services

Standards and reference materials to be used in the calibration of laboratory measuring instruments and used in laboratory research and analysis; Standards and reference materials to be used in the calibration of laboratory measuring instruments and used in laboratory research and analysis, namely, certified samples of botanical materials, chemical solids, and liquids in the nature of reagents and synthetic and natural oxides in the form of powders, liquids, pastes and granules.

Produits et services

Standards and reference materials to be used in the calibration of laboratory measuring instruments and used in laboratory research and analysis, namely, chemical standards and reference materials, other than for medical or veterinary purposes; Standards and reference materials to be used in the calibration of laboratory measuring instruments and used in laboratory research and analysis, namely, certified samples of botanical extracts and chemical solids, and liquids in the nature of reagents for laboratory research and analysis, and synthetic and natural oxides in the form of powders, liquids, pastes and granules for laboratory research and analysis other than for medical or veterinary purposes

Abrégé

A process is provided for microencapsulating nicotinamide riboside (NR), and other NR derivatives by using ethyl cellulose which may be polymerized in a particular manner. Further, compositions comprising NR or derivatives thereof microencapsulated in an edible biopolymer are provided.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 9/50 - Microcapsules

Abrégé

A process is provided for microencapsulating nicotinamide riboside (NR), and other NR derivatives by using ethyl cellulose which may be polymerized in a particular manner. Further, compositions comprising NR or derivatives thereof microencapsulated in an edible biopolymer are provided.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 47/38 - CelluloseSes dérivés
• A61K 9/50 - Microcapsules
• A61K 8/11 - Compositions encapsulées
• C07H 19/048 - Radicaux pyridine

Abrégé

The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): 8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof; and novel crystalline forms thereof.

Classes IPC  ?

• C07H 19/207 - Radicaux purine avec le radical saccharide estérifié par des acides phosphoriques ou polyphosphoriques les acides phosphoriques ou polyphosphoriques étant estérifiés par un autre composé hydroxylique, p. ex. les dinucléotides de la flavine-adénine ou de la nicotinamide-adénine
• C07H 19/048 - Radicaux pyridine
• C07D 307/20 - Atomes d'oxygène
• C07H 19/20 - Radicaux purine avec le radical saccharide estérifié par des acides phosphoriques ou polyphosphoriques
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle

Abrégé

The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): 8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof, and novel crystalline forms thereof.

Classes IPC  ?

• C07H 19/048 - Radicaux pyridine
• C07D 307/20 - Atomes d'oxygène
• C07H 19/20 - Radicaux purine avec le radical saccharide estérifié par des acides phosphoriques ou polyphosphoriques
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle

Produits et services

Sweets; ice cream; ice cream mixes; ice cream desserts; ice cream substitute; frozen dessert, namely, frozen confections and frozen dessert consisting of cream or cream substitutes; ice cream, cream, and cream-substitute based desserts, edible ices, and ice creams with chocolate, fruit, or tea flavoring; ice cream, cream, and cream-substitute based desserts, edible ices, and ice creams containing dietary and nutritional supplements

Abrégé

The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): 8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof; and novel crystalline forms thereof.

Classes IPC  ?

• A01N 43/04 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome
• A61K 31/70 - Hydrates de carboneSucresLeurs dérivés
• C07H 19/048 - Radicaux pyridine
• C07D 307/20 - Atomes d'oxygène
• C07H 19/20 - Radicaux purine avec le radical saccharide estérifié par des acides phosphoriques ou polyphosphoriques
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle

Abrégé

The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): 8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof; and novel crystalline forms thereof.

Classes IPC  ?

• C07H 19/048 - Radicaux pyridine
• C07D 307/20 - Atomes d'oxygène
• C07H 19/20 - Radicaux purine avec le radical saccharide estérifié par des acides phosphoriques ou polyphosphoriques
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle

Abrégé

Methods for delivering at least one compound selected from nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, in combination with at least one of thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), and pyridoxine (vitamin B6), to an infant human subject in need of said compound or compounds are provided.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 31/51 - Thiamines, p. ex. vitamine B1
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A61K 31/4415 - Pyridoxine, c.-à-d. vitamine B6
• A61K 31/455 - Acide nicotinique, c.-à-d. niacineSes dérivés, p. ex. esters, amides
• A61K 31/525 - Iso-alloxazines, p. ex. riboflavines, vitamine B2
• A61K 31/7064 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées
• A23L 33/19 - Protéines du lait
• A23L 33/00 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement
• A23L 33/15 - Vitamines
• A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur

Produits et services

On-line retail store services featuring dietary and nutritional supplements; Retail store services featuring dietary and nutritional supplements

Produits et services

Nutraceuticals for use as a dietary supplement; vitamin and mineral supplements; vitamins.

Produits et services

Providing educational information in the field of clinical research via a website. Medical and scientific research information in the field of cellular energy, nicotinamide adenine dinucleotide, and nicotinamide riboside; providing scientific information in the field of research regarding cellular energy, nicotinamide adenine dinucleotide, and nicotinamide riboside; providing scientific research information in the field of clinical studies.

Produits et services

Dietary and nutritional supplements On-line retail store services featuring dietary and nutritional supplements; Retail store services featuring dietary and nutritional supplements

Produits et services

Diagnostic test kits, other than for veterinary purposes; diagnostic preparations, agents, and substances for humans; dietary supplements for humans; nutritional supplements for humans; vitamins for humans; dietary supplement drink mix for humans; nutritional supplement drink mix for humans.

Produits et services

Medical and scientific research information in the field of cellular energy, nicotinamide adenine dinucleotide, and nicotinamide riboside; Providing scientific information in the field of research regarding cellular energy, nicotinamide adenine dinucleotide, and nicotinamide riboside; Providing scientific research information in the field of clinical studies; Providing a website featuring educational information in the field of clinical research

Produits et services

Dietary and nutritional supplements On-line retail store services featuring dietary and nutritional supplements; Retail store services featuring dietary and nutritional supplements

Abrégé

Compositions containing nicotinamide riboside (NR) are provided. NR containing compositions are used in the care or treatment of skin and skin conditions. In some embodiments, the invention relates to pharmaceutical compositions and cosmetic compositions containing nicotinamide riboside. In further embodiments, the invention relates to methods of using nicotinamide riboside to promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for improving cell and tissue survival. A method of treating signs or symptoms of aging or skin wrinkles in an individual is provided, comprising topically administering to the individual in need of such treatment an effective amount of the compound nicotinamide riboside, or salts thereof.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle

Abrégé

Methods for stabilizing or encapsulating at least one compound selected from the group consisting of nicotinamide riboside (NR), nicotinic acid riboside (NAR), nicotinamide mononucleotide (NMN), nicotinic acid mononucleotide (NaMN), derivatives thereof, or salts thereof, are provided. Compositions including wax prills, stabilized, or encapsulated forms of at least one compound selected from the group consisting of nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, are also provided.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 47/44 - Huiles, graisses ou cires couvertes par plus d’un des groupes Huiles, graisses ou cires naturelles ou naturelles modifiées, p. ex. huile de ricin, huile de ricin polyéthoxylée, cire de lignite, lignite, gomme-laque, colophane, cire d’abeille ou lanoline
• A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur

Abrégé

Methods for stabilizing or encapsulating at least one compound selected from the group consisting of nicotinamide riboside (NR), nicotinic acid riboside (NAR), nicotinamide mononucleotide (NMN), nicotinic acid mononucleotide (NaMN), derivatives thereof, or salts thereof, are provided. Compositions including wax prills, stabilized, or encapsulated forms of at least one compound selected from the group consisting of nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, are also provided.

Classes IPC  ?

• C07H 19/048 - Radicaux pyridine
• A61K 31/7052 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides
• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 31/44 - Pyridines non condenséesLeurs dérivés hydrogénés
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle

Abrégé

The present disclosure provides crystalline Form II of nicotinic acid riboside, crystalline Form II of nicotinic acid riboside triacetate, and methods of preparation thereof. In an embodiment, the present disclosure relates to crystalline forms of nicotinoyl ribosides, derivatives thereof, or salts, hydrates, solvates, or prodrugs thereof. In another embodiment, the present disclosure relates to synthetic sequences or processes that enable the efficient production of crystalline forms of nicotinoyl ribosides, derivatives thereof, or salts, hydrates, solvates, or prodrugs thereof.

Classes IPC  ?

• A61K 31/443 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'oxygène comme hétéro-atome du cycle
• A61K 31/455 - Acide nicotinique, c.-à-d. niacineSes dérivés, p. ex. esters, amides
• C07D 307/20 - Atomes d'oxygène
• C07H 19/048 - Radicaux pyridine

Abrégé

The present disclosure provides crystalline Form II of nicotinic acid riboside, crystalline Form II of nicotinic acid riboside triacetate, and methods of preparation thereof.

Classes IPC  ?

• A01N 43/04 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome
• A61K 31/70 - Hydrates de carboneSucresLeurs dérivés
• C07H 19/048 - Radicaux pyridine

Produits et services

Medical and scientific research information in the field of cellular energy, nicotinamide adenine dinucleotide, and nicotinamide riboside; Providing scientific information in the field of research regarding cellular energy, nicotinamide adenine dinucleotide, and nicotinamide riboside; Providing scientific research information in the field of clinical studies; Providing a website featuring educational information in the field of clinical research

Produits et services

On-line retail store services featuring dietary and nutritional supplements; Retail store services featuring dietary and nutritional supplements

Produits et services

Providing information about fitness, exercise, and workouts; On-line journals, namely, blogs featuring articles, information, in the field of health, fitness, exercise, workouts, wellness, lifestyle, and nutrition Providing information about health, lifestyle wellness, and nutrition

Abrégé

The present disclosure provides nicotinate/nicotinamide riboside compounds or derivatives of formula (I): 8 are described herein, reduced analogs thereof, and synthetic processes for the preparation thereof.

Classes IPC  ?

• C07H 19/00 - Composés contenant un hétérocycle partageant un hétéro-atome du cycle avec un radical saccharideNucléosidesMononucléotidesLeurs anhydro-dérivés
• C07H 19/048 - Radicaux pyridine
• C07H 1/00 - Procédés de préparation des dérivés du sucre
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle

Produits et services

Phytochemicals for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals and cosmetics; chemical reagents for non-medical purposes; chemical test kits, comprised of chemical reagents, for analytical measurement of raw material identity, potency and formulation consistency for laboratory or research use; chemicals for use in industry and science; chemicals for use in the biochemical and chemical industry; assays for research purposes; diagnostic preparations for scientific or research use and for health assessment. Diagnostic kits consisting primarily of monoclonal antibodies, buffers, and reagents for use in disease testing; diagnostic preparations for medical purposes; diagnostic agents, preparations and substances for medical purposes; dietary supplements and preparations; medical and veterinary preparations and articles; nutritional supplements. Downloadable mobile applications for managing and sharing information on one's health, fitness and nutrition; downloadable software in the nature of a mobile application for providing information in the fields of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition; downloadable mobile application software for the purpose of tracking and monitoring health, wellness and nutrition; computer software for providing information in the fields of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition. Providing information about fitness, exercise, and workouts; on-line journals, namely, blogs featuring articles, information, reviews and recipes in the field of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition.

Produits et services

Diagnostic kits consisting primarily of monoclonal antibodies, buffers, and reagents for use in disease testing; diagnostic preparations for medical purposes; diagnostic agents, preparations and substances for medical purposes; dietary supplements and preparations; medical and veterinary preparations and articles; nutritional supplements; dietary and nutritional supplements.

Abrégé

The present disclosure provides novel crystalline forms of nicotinoyl riboside compounds or derivatives of formula (I): 8 are described herein, modified derivatives thereof, and phosphorylated analogs thereof, or salts, solvates, or prodrugs thereof; and methods of preparation thereof.

Classes IPC  ?

• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle
• C07H 19/048 - Radicaux pyridine

Abrégé

The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): 8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof; and novel crystalline forms thereof.

Classes IPC  ?

• C07H 19/207 - Radicaux purine avec le radical saccharide estérifié par des acides phosphoriques ou polyphosphoriques les acides phosphoriques ou polyphosphoriques étant estérifiés par un autre composé hydroxylique, p. ex. les dinucléotides de la flavine-adénine ou de la nicotinamide-adénine
• C07H 19/048 - Radicaux pyridine
• C07D 307/20 - Atomes d'oxygène
• C07H 19/20 - Radicaux purine avec le radical saccharide estérifié par des acides phosphoriques ou polyphosphoriques
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle

Abrégé

The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): wherein X", Z 1, Z2, n, R 1, R2, R3, R4, R5, R6,, R7, and R 8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof; and novel crystalline forms thereof.

Classes IPC  ?

• A61K 31/455 - Acide nicotinique, c.-à-d. niacineSes dérivés, p. ex. esters, amides
• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• C07H 1/00 - Procédés de préparation des dérivés du sucre
• C07H 19/048 - Radicaux pyridine

Produits et services

Phytochemicals for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals and cosmetics; chemical reagents for non-medical purposes; chemical test kits, comprised of chemical reagents, for analytical measurement of raw material identity, potency and formulation consistency for laboratory or research use; chemicals for use in industry and science; chemicals for use in the biochemical and chemical industry; assays for research purposes; diagnostic preparations for scientific or research use. Dietary and nutritional supplements; diagnostic kits consisting of monoclonal antibodies, buffers, and reagents for use in disease testing; diagnostic preparations for medical purposes; diagnostic agents, preparations and substances for medical purposes; dietary supplements and preparations; medical and veterinary preparations and articles; nutritional supplements. Downloadable mobile applications for managing and sharing information on one's health, fitness and nutrition; downloadable software in the nature of a mobile application providing information in the fields of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition; downloadable mobile application software for the purpose of tracking and monitoring health, wellness and nutrition; computer software for providing information in the fields of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition. Providing information about health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition; publication of on-line journals, namely, blogs featuring articles, information, reviews and recipes in the field of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition.

Produits et services

Phytochemicals for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals; Chemical reagents for non-medical purposes; Chemicals for use in industry and science; Chemicals for use in the biochemical and chemical industry; Assays for research purposes; Diagnostic preparations for scientific or research use Dietary and nutritional supplements Providing information about fitness, exercise, and workouts; Providing a website featuring on-line journals in the nature of non-downloadable articles in the field of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition; Providing information and reviews about physical fitness, exercise and fitness workouts Providing information about health, lifestyle wellness, healthy eating and nutrition

Produits et services

(1) Phytochemical additives for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals and cosmetics; chemical reagents for non-medical purposes for use in the dietary and nutritional supplement industry; chemical test kits for analytical measurement of raw material identity, potency and formulation consistency for laboratory or research use; chemical additives for use in the manufacture of dietary and nutritional supplements; chemical compositions for use in dietary and nutritional supplements; assays for research purposes for use in the development of dietary and nutritional supplements (2) Dietary and nutritional supplements for general health and well-being (3) Diagnostic kits consisting primarily of monoclonal antibodies, buffers, and reagents for use in disease testing; diagnostic preparations for medical purposes for improvement of one's general health and wellbeing; diagnostic agents, preparations and substances for medical purposes for improvement of general health and well-being; dietary supplements and preparations for general health and well-being; medical preparations for improvement of general health and well-being and veterinary preparations for improvement of general health and well-being (4) Diagnostic preparations for improvement of general health and well-being (5) Downloadable mobile applications for managing and sharing information on one's general health, fitness and nutrition; downloadable software in the nature of a mobile application providing information in the fields of general health, fitness, exercise, workouts, well-being, personal lifestyle, healthy eating and nutrition; downloadable mobile application software for the purpose of tracking and monitoring general health, wellbeing and nutrition; computer software for providing information in the fields of general health, fitness, exercise, workouts, well-being, personal lifestyle, healthy eating and nutrition (1) Providing information about general health, fitness, exercise, workouts, well-being, personal lifestyle, healthy eating and nutrition; on-line journals, namely, blogs featuring articles, information, reviews and recipes in the field of general health, fitness, exercise, workouts, well-being, personal lifestyle, healthy eating and nutrition

Produits et services

Phytochemicals for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals and cosmetics; Chemical reagents for non-medical purposes; Chemicals for use in industry and science; Chemicals for use in the biochemical and chemical industry; Assays for research purposes; Diagnostic preparations for scientific or research use Dietary supplements; Nutritional supplements

Abrégé

Compositions are provided including nicotinic acid riboside (“NAR”), and derivatives thereof including 1-(2′,3′,5′-triacetyl-beta-D-ribofuranosyl)-nicotinic acid (“NAR triacetate” or “NARTA”); or derivatives of a reduced form of nicotinic acid riboside (“NARH”), including 1-(2′,3′,5′-triacetyl-beta-D-ribofuranosyl)-1,4-dihydronicotinic acid (“NARH triacetate” or “NARH-TA”); or derivatives of nicotinamide riboside (“NR”), including 1-(2′,3′,5′-triacetyl-beta-D-ribofuranosyl)-nicotinamide (“NR triacetate” or “NRTA”); derivatives of a reduced form of nicotinamide riboside (“NRH”), including 1-(2′,3′,5′-triacetyl-beta-D-ribofuranosyl)-1,4-dihydronicotinamide (“NRH triacetate” or “NRH-TA”); or salts or prodrugs thereof, for use in food or beverage applications, pharmaceutical formulations, or as a dietary supplement. Methods of using the compounds above to promote the increase of intracellular levels of nicotinamide adenine dinucleotide (“NAD+”) or NADH in cells and tissues for improving cell and tissue survival or overall cell and tissue health are provided.

Classes IPC  ?

• A01N 43/04 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome
• A61K 31/70 - Hydrates de carboneSucresLeurs dérivés
• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle

Abrégé

Compositions are provided including nicotinic acid riboside ("NAR"), and derivatives thereof including l -(2',3 ',5'-triacetyl-beta-D-ribofuranosyl)-nicotinic acid ("NAR triacetate" or "NARTA"); or derivatives of a reduced form of nicotinic acid riboside ("NARH"), including 1 - (2',3',5 '-triacetyl-beta-D-ribofuranosyl)-1,4-dihydronicotinic acid ("NARH triacetate" or "NARJT-TA"); or derivatives of nicotinamide riboside ("NR"), including 1 -(2',3',5'-triacetyl- beta-D-ribofuranosyl)-nicotinamide ("NR triacetate" or "NRTA"); derivatives of a reduced form of nicotinamide riboside ("NRH"), including 1-(2',3 ',5'-triacetyl-beta-D-ribofuranosyl)- 1,4- dihydronicotinamide ("NRH triacetate" or "NRH-TA"); or salts or prodrugs thereof, for use in food or beverage applications, pharmaceutical formulations, or as a dietary supplement. Methods of using the compounds above to promote the increase of intracellular levels of nicotinamide adenine dinuc!eotide ("NAD+") or NADH in cells and tissues for improving cell and tissue survival or overall cell and tissue health are provided.

Classes IPC  ?

• A61K 31/44 - Pyridines non condenséesLeurs dérivés hydrogénés
• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 31/7052 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides
• C07H 19/00 - Composés contenant un hétérocycle partageant un hétéro-atome du cycle avec un radical saccharideNucléosidesMononucléotidesLeurs anhydro-dérivés
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle
• C07H 19/048 - Radicaux pyridine

Abrégé

Methods for delivering at least one compound selected from nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, in combination with at least one of thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), and pyridoxine (vitamin B6), to an infant human subject in need of said compound or compounds are provided.

Classes IPC  ?

• A61K 31/7064 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées
• A23L 33/00 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement
• A23L 33/15 - Vitamines
• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 31/51 - Thiamines, p. ex. vitamine B1
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A61K 31/4415 - Pyridoxine, c.-à-d. vitamine B6
• A61K 31/455 - Acide nicotinique, c.-à-d. niacineSes dérivés, p. ex. esters, amides
• A61K 31/525 - Iso-alloxazines, p. ex. riboflavines, vitamine B2
• A23L 33/19 - Protéines du lait
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine

Abrégé

Methods for delivering at least one compound selected from nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, in combination with at least one of thiamine (vitamin Bl), riboflavin (vitamin B2), niacin (vitamin B3), and pyridoxine (vitamin B6), to an infant human subject in need of said compound or compounds are provided.

Classes IPC  ?

• A61K 31/44 - Pyridines non condenséesLeurs dérivés hydrogénés
• A61K 31/455 - Acide nicotinique, c.-à-d. niacineSes dérivés, p. ex. esters, amides
• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• C07H 7/06 - Radicaux hétérocycliques
• A23L 33/15 - Vitamines

Abrégé

The present disclosure provides nicotinate/nicotinamide riboside compounds or derivatives of formula (I): 8 are described herein, reduced analogs thereof, and synthetic processes for the preparation thereof.

Classes IPC  ?

• C07H 19/00 - Composés contenant un hétérocycle partageant un hétéro-atome du cycle avec un radical saccharideNucléosidesMononucléotidesLeurs anhydro-dérivés
• C07H 19/048 - Radicaux pyridine
• C07H 1/00 - Procédés de préparation des dérivés du sucre
• C07H 19/04 - Radicaux hétérocycliques contenant uniquement des atomes d'azote comme hétéro-atomes du cycle

Abrégé

The present disclosure provides nicotinate/nicotinamide riboside compounds or derivatives of formula (I): wherein X-, Z1 Z2, n, R1, R2, R3, R4, R5, R6, R7, and R8 are described herein, reduced analogs thereof, and synthetic processes for the preparation thereof.

Classes IPC  ?

• A01N 43/40 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un atome d'azote comme unique hétéro-atome du cycle des cycles à six chaînons
• A61K 31/44 - Pyridines non condenséesLeurs dérivés hydrogénés

Produits et services

Providing information about fitness, exercise, and workouts; On-line journals, namely, blogs featuring articles, information, reviews and recipes in the field of health, fitness, exercise, workouts, wellness, lifestyle, healthy eating and nutrition Providing information about health, lifestyle wellness, healthy eating and nutrition

Produits et services

Dietary and nutritional supplements

Produits et services

Phytochemicals for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals and cosmetics. Dietary and nutritional supplements.

Produits et services

(1) Phytochemical additives for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals and cosmetics (2) Dietary and nutritional supplements for general health and well being

Abrégé

A synthetic process is provided for the preparation of phosphorylated analogs of nicotinamide riboside ("NR") having the formula (I), or salts thereof, and reduced or modified derivatives thereof, having the formula (II), wherein X-, Y1, Y2, Z1, Z2, n, R1, R2, R3, R4, R5, R6, and R7 are as defined herein. The present disclosure also relates to the preparation of phosphorylated analogs of nicotinic acid riboside ("NAR") having the formula (I), or salts thereof, and reduced or modified derivatives thereof, having the formula (II). Generally solvent-free conditions are employed using appropriate mechano-chemical techniques as described. (I) (II)

Classes IPC  ?

• A01N 43/40 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un atome d'azote comme unique hétéro-atome du cycle des cycles à six chaînons
• A61K 31/44 - Pyridines non condenséesLeurs dérivés hydrogénés

Produits et services

(1) Nutraceuticals for use as a dietary supplement for general health and well-being; vitamin and mineral supplements; vitamins

Abrégé

Derivatives of nicotinic acid riboside (NAR), nicotinamide riboside (NR), and reduced NAR and NR, including 1-(2′,3′,5′-triacetyl-beta-D-ribofuranosyl)-1,4-dihydronicotinic acid (4a), and compositions containing the same and/or reduced derivative forms of nicotinamide riboside including 1-(2′,3′,5′-triacetyl-beta-D-ribofuranosyl)-1,4-nicotinamide (2), are provided for use in the care of treatment of skin and skin conditions. In some embodiments, the invention relates to pharmaceutical compositions and cosmetic compositions containing one or more NR, NAR, NRH, or NARH derivatives, or prodrugs or salts thereof. In further embodiments, the invention relates to methods of using one or more NR, NAR, NRH, or NARH derivatives, or prodrugs, solvates, or salts thereof, to promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for improving cell and tissue survival and overall cell and tissue health.

Classes IPC  ?

• C07H 19/048 - Radicaux pyridine
• A61Q 19/08 - Préparations contre le vieillissement
• A61Q 19/00 - Préparations pour les soins de la peau
• A61K 8/67 - Vitamines

Abrégé

Derivatives of nicotinic acid riboside (NAR), nicotinamide riboside (NR), and reduced NAR and NR, including 1-(2', 3', 5'-triacetyl-beta-D-ribofuranosyl)-1,4-dihydronicotinic acid (4a), and compositions containing the same and/or reduced derivative forms of nicotinamide riboside including 1-(2',3',5'-triacetyl-beta-D-ribofuranosyl)-1,4-nicotinamide (2), are provided for use in the care of treatment of skin and skin conditions. In some embodiments, the invention relates to pharmaceutical compositions and cosmetic compositions containing one or more NR, NAR, NRH, or NARH derivatives, or prodrugs or salts thereof. In further embodiments, the invention relates to methods of using one or more NR, NAR, NRH, or NARH derivatives, or prodrugs, solvates, or salts thereof, to promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for improving cell and tissue survival and overall cell and tissue health.

Classes IPC  ?

• C07H 19/048 - Radicaux pyridine
• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle

Abrégé

Compositions containing nicotinamide riboside (NR) are provided. NR containing compositions are used in the care or treatment of skin and skin conditions. In some embodiments, the invention relates to pharmaceutical compositions and cosmetic compositions containing nicotinamide riboside. In further embodiments, the invention relates to methods of using nicotinamide riboside to promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for improving cell and tissue survival. A method of treating signs or symptoms of aging or skin wrinkles in an individual is provided, comprising topically administering to the individual in need of such treatment an effective amount of the compound nicotinamide riboside, or salts thereof.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle

Produits et services

Nutraceuticals for use as a dietary supplement; Vitamin and mineral supplements; Vitamins

Produits et services

Dietary supplements and dietetic preparations; Medical and veterinary preparations and articles; Nutritional supplements.

Abrégé

Compositions containing nicotinamide riboside (NR) are provided. NR containing compositions are used in the care or treatment of skin and skin conditions. In some embodiments, the invention relates to pharmaceutical compositions and cosmetic compositions containing nicotinamide riboside. In further embodiments, the invention relates to methods of using nicotinamide riboside to promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for improving cell and tissue survival. A method of treating signs or symptoms of aging or skin wrinkles in an individual is provided, comprising topically administering to the individual in need of such treatment an effective amount of the compound nicotinamide riboside, or salts thereof.

Classes IPC  ?

• C07H 19/048 - Radicaux pyridine

Produits et services

Phytochemicals for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals and cosmetics; Chemical reagents for non-medical purposes; Chemical test kits for analytical measurement of raw material identity, potency and formulation consistency for laboratory or research use; Chemicals for use in industry and science; Chemicals for use in the biochemical and chemical industry; Assays for research purposes Dietary and nutritional supplements Innovation consulting services, namely, advising others in the areas of product development; Product development consulting in the field of dietary supplements, nutritional products, pharmaceuticals and cosmetics; Scientific consulting and research services relating to foods and dietary supplements; Chemical, biochemical, biological and bacteriological research and analysis; Consulting in the field of product development in the field of chemicals; Development and establishment of testing specifications and procedures in the field of chemicals; Development and test of chemical production methods; Development of voluntary standards for chemicals; Executing of chemical analyses; Industrial research in the field of chemicals; Pharmaceutical research and development; Product research and development; Research and development and consultation related thereto in the field of chemicals; Testing of raw materials

Abrégé

A method is provided for treating an individual for a cellular proliferative disorder, including administering to the individual in need of such treatment a therapeutically effective amount of the compound pterostilbene wherein UDP-glucuronosyltransferase (UGT) activity is increased. In an embodiment, 12-HETE levels can be reduced by administration of pterostilbene.

Classes IPC  ?

• A61K 31/05 - Phénols
• A61K 31/08 - Éthers ou acétals acycliques, p. ex. paraformaldéhyde

Abrégé

A pharmaceutical composition is provided comprising a therapeutically effective amount of pterostilbene, a therapeutically effective amount of curcumin, and a pharmaceutically acceptable carrier. The embodiments of the pharmaceutical compositions can have lipid lowering properties, or alternatively can have properties that can treat oxidative stress, by decreasing inflammation or inflammatory processes contributing to digestive disorders or cancer. A method of treating an individual for an inflammatory disorder is provided, comprising administering to the individual in need of such treatment a pharmaceutical composition including a therapeutically effective amount of pterostilbene, a therapeutically effective amount of a curcumin, and a pharmaceutically acceptable carrier. The combination containing pterostilbene and curcumin is effective for treatment or prevention of oxidative stress, treatment of digestive disorders including inflammatory bowel disease, and/or to reduce or inhibit inflammation, in both animals and in humans.

Classes IPC  ?

• A61K 31/09 - Éthers ou acétals ayant une liaison éther à un carbone cyclique d'un noyau aromatique ayant plusieurs liaisons éther
• A61K 31/12 - Cétones

Abrégé

A pharmaceutical composition is provided comprising a therapeutically effective amount of pterostilbene, a therapeutically effective amount of a polyphenolic-PVP extract of grape juice, and a pharmaceutically acceptable carrier. The embodiments of the pharmaceutical compositions can have lipid lowering properties, or alternatively can have properties that can treat oxidative stress, by decreasing inflammation or inflammatory processes contributing to neurodegenerative diseases. A method of lowering lipid levels in an individual is also provided, comprising administering to the individual in need of such treatment a pharmaceutical composition including a therapeutically effective amount of pterostilbene, a therapeutically effective amount of a polyphenolic-PVP extract of grape juice, and a pharmaceutically acceptable carrier, wherein lipid levels are decreased.

Classes IPC  ?

• A61K 31/05 - Phénols
• A61K 36/87 - Vitaceae ou Ampelidaceae (famille de la vigne ou du raisin), p. ex. raisin, vitis rotumdifolia ou vigne vierge

Produits et services

Phytochemicals for use in the manufacturing of dietary supplements, nutritional products [, pharmaceuticals and cosmetics ] Dietary and nutritional supplements

Abrégé

A pharmaceutical composition is provided comprising a therapeutically effective amount of pterostilbene, a therapeutically effective amount of a statin compound, and a pharmaceutically acceptable carrier. The embodiments of the pharmaceutical compositions can have lipid lowering properties, or alternatively can have properties that can treat oxidative stress, by decreasing inflammation or inflammatory processes contributing to neurodegenerative diseases. A method of lowering lipid levels in an individual is also provided, comprising administering to the individual in need of such treatment a pharmaceutical composition including a therapeutically effective amount of pterostilbene, a therapeutically effective amount of a statin compound, and a pharmaceutically acceptable carrier, wherein lipid levels are decreased.

Classes IPC  ?

• A61K 38/00 - Préparations médicinales contenant des peptides

Produits et services

Phytochemicals for use in the manufacturing of dietary supplements, nutritional products, * and * pharmaceuticals [ and cosmetics ]

Produits et services

Phytochemicals for use in the manufacturing of dietary supplements, nutritional products, pharmaceuticals and cosmetics

Produits et services

Chemical reagents for non-medical purposes; chemical test kits for analytical measurement of raw material identity, potency and formulation consistency for laboratory or research use; chemicals for use in industry and science; chemicals for use in the biochemical and chemical industry; assays for research purposes. Chemical, biochemical, biological and bacteriological research and analysis; consulting in the field of product development in the field of chemicals; development and establishment of testing specifications and procedures in the field of chemicals; development and test of chemical production methods; development of voluntary standards for chemicals; executing of chemical analyses; industrial research in the field of chemicals; pharmaceutical research and development; Product research and development; Research and development and consultation related thereto in the field of chemicals; testing of raw materials.

Produits et services

Phytochemicals for use in the manufacturing of dietary supplements and nutritional products

Produits et services

[ Chemical reagents for non-medical purposes; ] Chemical test kits for analytical measurement of raw material identity, potency and formulation consistency for laboratory or research use; Chemicals for use in industry and science; Chemicals for use in the biochemical and chemical industry; Assays for research purposes Chemical, biochemical, biological and bacteriological research and analysis; Consulting in the field of product development in the field of chemicals; Development and establishment of testing specifications and procedures in the field of chemicals; Development and test of chemical production methods; Development of voluntary standards for chemicals; Executing of chemical analyses; [ Industrial research in the field of chemicals; ] Pharmaceutical research and development; Product research and development; Research and development and consultation related thereto in the field of chemicals; Testing of raw materials