BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (USA)
CARNEGIE INSTITUTION OF WASHINGTON (USA)
Inventeur(s)
Rouached, Hatem
Rhee, Seung Yon
Abrégé
Plants having modified expression or activity of a protein kinase polypeptide are provided. Methods for modifying expression or activity of the protein kinase polypeptide include genome editing to modify the transcription regulatory region or sequence encoding the protein kinase polypeptide as well as transformation with a heterologous polynucleotide encoding the protein kinase polypeptide. Plants containing the modifications have improved phosphorus use efficiency, increased tolerance to phosphorus deficiency, and improved yield in phosphorus deficient conditions.
The present invention provides carbon-based clathrate compounds, including a carbon-based clathrate compound that includes a clathrate lattice with atoms of at least one element selected from the group consisting of carbon and boron as a host cage structure and guest atoms encapsulated within the clathrate lattice. The guest atoms can constitute single elements or multiple distinct elements. In one embodiment, the invention provides a carbon-based clathrate compound of the formula NdB3C3. In another embodiment, the invention provides a carbon-based clathrate-like compound of the formula CaB3C3. In another embodiment, the invention provides a carbon-based clathrate compound of the formula NaxSr(1-x)B3C3.
C01F 17/30 - Composés contenant des métaux de terres rares et au moins un élément autre qu’un métal des terres rares, l'oxygène ou l'hydrogène, p. ex. La4S3Br6
C01F 11/00 - Composés du calcium, du strontium ou du baryum
3.
BORON-STABILIZED TYPE-I AND TYPE-II CARBON CLATHRATES
The present invention provides type-I and II carbon-based clathrate compounds stabilized by boron, including a boron-substituted, carbon-based framework with guest atoms encapsulated within the clathrate lattice. In one embodiment, the invention provides a carbon-based type-I clathrate compound of the formula Ca8BxC46-x.
The Board of Trustees of the Leland Stanford Junior University (USA)
Carnegie Institution of Washington (USA)
Inventeur(s)
Kunz, Larissa
Majumdar, Arunava
Cargnello, Matteo
Dinneny, Jose R.
Grossman, Arthur
Abrégé
In some embodiments, there may be provided a luminescent material or a persistent luminescent (PersL) material that is used to redistribute sunlight. Related systems, methods, and articles of manufacture are also disclosed.
A01G 9/24 - Dispositifs de chauffage, d'aération, de régulation de la température ou d'irrigation dans les serres, les châssis ou les installations similaires
C09K 11/77 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant des métaux des terres rares
An example system includes a fluid delivery device configured to deliver gas nanobubbles to a target site of a patient from a solution comprising a fluid, supersaturated with a. gas, wherein the fluid delivery' device defines a flow channel configured to flow the solution through the flow channel such that the gas in the supersaturated fluid forms gas nanobubbles as the solution flows through the flow channel towards the target site, and wherein the gas nanobubbles remain in the fluid at least until delivery' to the target site.
A61M 5/14 - Dispositifs de perfusion, p. ex. perfusion par gravitéPerfusion sanguineAccessoires à cet effet
A61K 33/00 - Préparations médicinales contenant des ingrédients actifs inorganiques
A61M 5/36 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras avec des moyens pour éliminer l'air ou pour empêcher l'injection ou l'introduction d'air dans le corps
6.
FLOE1-MEDIATED MODULATION OF SEED LONGEVITY AND GERMINATION RATES
The Board of Trustees of the Leland Stanford Junior University (USA)
Carnegie Institution of Washington (USA)
Inventeur(s)
Dorone, Yanniv
Boeynaems, Steven
Gitler, Aaron D.
Rhee, Seung Yon
Abrégé
Described herein are methods of modulating seed germination and seed longevity in plants by modifying FLOE1 level or activity; and plants generated by such methods.
A novel bulk form of 4H-Si, a crystalline allotrope of silicon and a novel method of manufacture. The novel material consists of highly oriented microcrystals of silicon in the 4H structure with no disordered material. The 4H-Si is derived from heating a second novel material Si24 under proper conditions. The allotrope of silicon is produced as bulk, microcrystalline agglomerates.
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (USA)
CARNEGIE INSTITUTION OF WASHINGTON (USA)
Inventeur(s)
Rouached, Hatem
Rhee, Seung Yon
Abrégé
Plants having modified expression or activity of a protein kinase polypeptide are provided. Methods for modifying expression or activity of the protein kinase polypeptide include genome editing to modify the transcription regulatory region or sequence encoding the protein kinase polypeptide as well as transformation with a heterologous polynucleotide encoding the protein kinase polypeptide. Plants containing the modifications have improved phosphorus use efficiency, increased tolerance to phosphorus deficiency, and improved yield in phosphorus deficient conditions.
C01F 11/00 - Composés du calcium, du strontium ou du baryum
C01F 17/30 - Composés contenant des métaux de terres rares et au moins un élément autre qu’un métal des terres rares, l'oxygène ou l'hydrogène, p. ex. La4S3Br6
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (USA)
CARNEGIE INSTITUTION OF WASHINGTON (USA)
Inventeur(s)
Jonikas, Martin C.
Fauser, Friedrich Alexander
Jinkerson, Robert Edward
Blasi, Josep Vilarrasa
Abrégé
Described herein is a screen of the Chlamydomonas genome that provides more than 700 high confidence gene/phenotype relationships. The identification of these relationships enables use of the genes to influence the correspond phenotype in a heterologous organism, such as a plant or another photosynthetic organism. Additional aspects of the present disclosure provide genetically altered plants having a heterologous polypeptide to which a phenotype is now linked, or having a modified native homolog of that polypeptide (for instance, a knockout or other modification that reduces or increases expression). Other aspects of the present disclosure relate to methods of making such plants, as well as cultivating these genetically altered plants.
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (USA)
CARNEGIE INSTITUTION OF WASHINGTON (USA)
Inventeur(s)
Kunz, Larissa
Majumdar, Arunava
Cargnello, Matteo
Dinneny, Jose, R.
Grossman, Arthur
Abrégé
In some embodiments, there may be provided a luminescent material or a persistent luminescent (PersL) material that is used to redistribute sunlight. Related systems, methods, and articles of manufacture are also disclosed.
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (USA)
CARNEGIE INSTITUTION OF WASHINGTON (USA)
Inventeur(s)
Dorone, Yanniv
Boeynaems, Steven
Gitler, Aaron D.
Rhee, Seung Yon
Abrégé
Described herein are methods of modulating seed germination and seed longevity in plants by modifying FLOE1 level or activity; and plants generated by such methods.
The disclosure provides compositions and methods for infecting a legume plant and/or increasing the yield of a legume plant by providing a population of light-activated, nitrogen-fixing bacteria by illuminating a population of nitrogen-fixing bacteria with a blue light and delivering to the legume plant the population of light-activated, nitrogen-fixing bacteria.
A01H 3/02 - Procédés de modification des phénotypes par contrôle de la durée, de la longueur d'onde, de l'intensité ou de la périodicité de l'éclairement
C01F 17/30 - Composés contenant des métaux de terres rares et au moins un élément autre qu’un métal des terres rares, l'oxygène ou l'hydrogène, p. ex. La4S3Br6
15.
COMPOSITIONS AND METHODS FOR INCREASING PLANT YIELD
The disclosure provides compositions and methods for infecting a legume plant and/or increasing the yield of a legume plant by providing a population of light-activated, nitrogen-fixing bacteria by illuminating a population of nitrogen-fixing bacteria with a blue light and delivering to the legume plant the population of light-activated, nitrogen-fixing bacteria.
A01H 3/00 - Procédés de modification des phénotypes
A01N 63/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des micro-organismes, des virus, des champignons microscopiques, des animaux ou des substances produites par, ou obtenues à partir de micro-organismes, de virus, de champignons microscopiques ou d'animaux, p. ex. enzymes ou produits de fermentation
C12N 13/00 - Traitement de micro-organismes ou d'enzymes par énergie électrique ou ondulatoire, p. ex. par magnétisme, par des ondes sonores
Compositions and methods are provided for increasing the levels of at least one sugar in a plant cell or plant part. Plants are provided having a first heterologous nucleic acid sequence encoding a SWEET13 protein operably linked to a promoter active in a plant cell. Further provided are expression constructs for expression of SWEET13 in specific tissues of the plant. Based on promoter selection, SWEET13 can be used to increase transport of sugar at the source in the leaves, or at the sink in the seeds. Likewise, by expressing SWEET13 in the leaves in order to facilitate phloem loading and in the seed in order to increase sugar unloading and seed filling, overall sugar transport can be increased in an effort to increase total yield.
Nanodiamonds are grown under conditions where diamond-like organic seed molecules do not decompose. This permits engineered growth of fluorescent nanodiamonds wherein a custom designed seed molecule can be incorporated at the center of a nanodiamond. By substituting atoms at particular locations in the seed molecule it is possible to achieve complex multi-atom diamond color centers or even to engineer complete quantum registers. In addition, it is possible to grow ultra-small nanodiamonds, wherein each nanodiamond, no matter how small, can have at least one bright and photostable fluorescent emitter.
Methods of ChlP-seq are disclosed herein. These methods of ChlP-seq employ carrier DNA to prevent loss of DNA samples. The greater DNA yields achieved by the presently disclosed technology permit ChlP-seq of a small number of cells, permitting epigenetic analysis of primary cells of limited quantity.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G06F 19/20 - pour l'hybridation ou l'expression génique, p.ex. microréseaux, séquençage par hybridation, normalisation, profilage, modèles de correction de bruit, estimation du ratio d'expression, conception ou optimisation de sonde
G06F 19/24 - pour l'apprentissage automatique, l'exploration de données ou les bio statistiques, p.ex. détection de motifs, extraction de connaissances, extraction de règles, corrélation, agrégation ou classification
Compositions and methods are provided for increasing the levels of at least one sugar in a plant cell or plant part. Plants are provided having a first heterologous nucleic acid sequence encoding a transfer cell-specific protein and a second heterologous nucleic acid sequence encoding a sugar transporter, such as SWEET 4c. Further provided are expression constructs for expression of the transfer cell-specific protein and sugar transporter. Methods are provided for increasing sugar content in a plant or plant cell by introducing into a plant a first heterologous nucleic acid sequence encoding a transfer cell- specific protein operably linked to a promoter functional in a plant and a second heterologous nucleic acid sequence encoding a sugar transporter operably linked to a promoter functional in a plant.
Novel methods of ChlP-seq are disclosed herein. These methods of ChlP-seq employ carrier DNA to prevent loss of DNA samples. The greater DNA yields achieved by this invention permit ChlP-seq of a small number of cells, permitting epigenetic analysis of primary cells of limited quantity.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 33/483 - Analyse physique de matériau biologique
The present invention relates generally to an integrated system, apparatus and method that allows for the continuous culturing of microorganisms under high pressure conditions and at a wide range of temperatures. More specifically, the system is configured to be gas tight and operate under aerobic or anaerobic conditions. The system is also configured to permit periodic sampling of the incubated organisms under such conditions with minimal physical/chemical disturbance inside the reactor and minimal impacts of shear forces on the collected biomass.
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
C12M 1/02 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'agitationAppareillage pour l'enzymologie ou la microbiologie avec des moyens d'échange de chaleur
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
The present disclosure provides methods and products for photosynthetic acclimation of plants and increased photosynthetic efficiency and biomass production, as well as other advantageous agronomic traits, in fluctuating light environments.
C12N 15/29 - Gènes codant pour des protéines végétales, p. ex. thaumatine
C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux
C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique
The invention relates to a new phase of silicon, Si24, and a method of making the same. Si24 has a quasi-direct band gap, with a direct gap value of 1.34 eV and an indirect gap value of 1.3 eV. The invention also relates to a compound of the formula Na4Si24 and a method of making the same. Na4Si24 may be used as a precursor to make Si24.
The present invention relates to methods of increasing the levels of at least one sugar in developing seeds in a plant, with the methods comprising inserting an exogenous nucleic acid, which codes for at least one sugar transporter protein (SWEET protein), into a plant cell to create a transgenic plant cell, and subjecting the transgenic plant cell to conditions that promote expression of the at least one SWEET protein during seed development. The methods results in transgenic plant seeds, and transgenic plants that produce seed, where the levels of at least one sugar are increased as compared to seeds from non-transgenic plants of the same species grown under the same conditions.
Novel methods of ChlP-seq are disclosed herein. These methods of ChlP-seq employ carrier DNA to prevent loss of DNA samples. The greater DNA yields achieved by this invention permit ChlP-seq of a small number of cells, permitting epigenetic analysis of primary cells of limited quantity.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C12P 21/06 - Préparation de peptides ou de protéines préparés par hydrolyse d'une liaison peptidique, p. ex. hydrolysats
28.
GENETICALLY ENCODED PROBE FOR QUANTIFICATION OF LACTATE, AND METHODS FOR QUANTIFYING METABOLIC RATES AND LACTATE TRANSPORT
CENTRO DE ESTUDIOS CIENTIFICOS DE VALDIVIA (Chili)
CARNEGIE, INSTITUTION OF WASHINGTON (USA)
Inventeur(s)
Barros Olmedo, Luis Felipe
San Martin, Alejandro
Ceballo Charpentier, Sebastian
Frommer, Wolf, B.
Abrégé
A nanosensor for detecting and quantifying lactate in different types of samples, such as tissues, intra-cellular and subcellular compartments, with high spatial and temporal resolution is disclosed. Methods comprising use of the nanosensor for quantifying the activity of lactate transporters, rates of cellular lactate production and cellular lactate consumption, and rate of mitochondrial pyruvate consumption are also disclosed. Methods for quantifying the transformation in energy metabolism that characterizes cancer cells with single-cell resolution and for detecting interference of candidate drugs with mitochondrial energetics are additionally disclosed.
C07K 1/00 - Procédés généraux de préparation de peptides
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
29.
PATHOGEN RESISTANT PLANT CELLS AND METHODS OF MAKING
The present invention relates to genetically modified plant cells that have reduced expression or activity of at least one amino acid efflux transporter and/or at least one mineral efflux transporter compared to levels of expression or activity of the at least one amino acid efflux transporter or mineral efflux transporter in an unmodified plant cell. The present invention also relates to genetically modified plant cells that have increased expression or activity of at least one amino acid influx transporter and/or at least one mineral influx transporter compared to levels of expression or activity of the at least one amino acid influx transporter or mineral influx transporter in an unmodified plant cell.
The present invention provides systems and methods to automatically analyze Landsat satellite data of forests. The present invention can easily be used to monitor any type of forest disturbance such as from selective logging, agriculture, cattle ranching, natural hazards (fire, wind events, storms), etc. The present invention provides a large-scale, high-resolution, automated remote sensing analysis of such disturbances.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
The present invention relates to genetically modified plant cells that have altered expression or activity of at least one sucrose efflux transporter compared to levels of expression or activity of the at least one sucrose efflux transporter in an unmodified plant cell.
The disclosure relates to engineered transporter proteins comprising at least one fluorescent reporter covalently bound to the transporter protein, wherein the transporter proteins comprise a structural inverted repeat motif, with the motif comprising a first and second subunit that are structural inverted repeats of one another and that are joined to one another by a polypeptide loop.
C07K 1/00 - Procédés généraux de préparation de peptides
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
2N that are polar insulators. A comprises one or more cations or set of cations that sit in sites derived from the A-site in the perovskite structure. B comprises one or more cations or set of cations that sit in sites derived from the B-site in the perovskite structure. C comprises oxygen, O, with optionally some nitrogen, N, and D comprises N, with optionally some O. The total valence of the cations A+B is equal to the total valence of the anions 2 C+D. Also disclosed are methods of producing such oxynitride perovskites and uses of such oxynitride perovskites.
The present invention provides systems and methods to automatically analyze Landsat satellite data of forests. The present invention can easily be used to monitor any type of forest disturbance such as from selective logging, agriculture, cattle ranching, natural hazards (fire, wind events, storms), etc. The present invention provides a large-scale, high-resolution, automated remote sensing analysis of such disturbances.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
35.
METHOD TO MEASURE THE METABOLIC RATE OR RATE OF GLUCOSE CONSUMPTION OF CELLS OR TISSUES WITH HIGH SPATIOTEMPORAL RESOLUTION USING A GLUCOSE NANOSENSOR
CENTRO DE ESTUDIOS CIENTIFICOS DE VALDIVIA (Chili)
CARNEGIE, INSTITUTION OF WASHINGTON (USA)
Inventeur(s)
Barros Olmedo, Luis, Felipe
Bittner Hofmann, Carla, Ximena
Abrégé
A method to measure the metabolic rate or rate of glucose consumption of cells or tissues with high spatiotemporal resolution using a glucose nanosensor is disclosed. The method generally includes providing single cells or cell populations, cells in suspension or adherent, in a cell culture, a tissue culture, a mixed cell culture, a tissue explant, or in animal tissues in vivo for the measurement of glucose metabolic rate; expressing a glucose sensor in individual cells; calibrating the sensor in controlled conditions; disrupting the steady-state of glucose entering the cell; recording the output from the sensor and calculating the corresponding glucose concentration at different times; and determining the glucose metabolic rate. The method can be applied for the screening of molecules with pharmacological potential, determination of glucose rate of cancerous cells, tissue physiology and biochemistry research.
The invention relates to single crystal diamond with high optical quality and methods of making the same. The diamond possesses an intensity ratio of the second-order Raman peak to the fluorescence background of around 5 or greater.
C23C 16/511 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement au moyen de décharges électriques utilisant des décharges à micro-ondes
C23C 16/50 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement au moyen de décharges électriques
The invention relates to single crystal diamond with high optical quality and methods of making the same. The diamond possesses an intensity ratio of the second-order Raman peak to the fluorescence background of around 5 or greater.
2N that are polar insulators. A comprises one or more cations or set of cations that sit in sites derived from the A-site in the perovskite structure. B comprises one or more cations or set of cations that sit in sites derived from the B-site in the perovskite structure. C comprises oxygen, O, with optionally some nitrogen, N, and D comprises N, with optionally some O. The total valence of the cations A+B is equal to the total valence of the anions 2 C+D. Also disclosed are methods of producing such oxynitride perovskites and uses of such oxynitride perovskites.
C04B 35/50 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base de composés de terres rares
C04B 35/505 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base de composés de terres rares à base d'oxyde d'yttrium
H01L 41/18 - Emploi de matériaux spécifiés pour des éléments piézo-électriques ou électrostrictifs
A novel class of transporter protein, referred to as SWEET, GLUE or Glϋ, is disclosed. These transporters provide a novel system for the transportation of sugars across membranes within a cell and between the inside and outside of a cell. Such transporters are useful for understanding and altering the sugar concentration within certain organs of an organism, and within certain organelles within the cell. These transporters are also useful in protecting plants from a pathogen attack.
C07H 21/00 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques
C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
40.
INSULT RESISTANT PLANTS AND METHODS OF PRODUCING AND USING THE SAME
C12N 15/83 - Vecteurs viraux, p. ex. virus de la mosaïque du chou-fleur
A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique
41.
PRODUCTION OF SINGLE CRYSTAL CVD DIAMOND RAPID GROWTH RATE
In a method of producing diamonds by microwave plasma-assisted chemical vapor deposition which comprises providing a substrate and establishing a microwave plasma ball in an atmosphere comprising hydrogen, a carbon source and oxygen at a pressure and temperature sufficient to cause the deposition of diamond on said substrate, the improvement wherein the diamond is deposited under a pressure greater than 400 torr at a growth rate of at least 200 μm/hr. from an atmosphere which is either essentially free of nitrogen or includes a small amount of nitrogen.
1/2. The invention further relates to a method of manufacturing single crystal boron doped CVD diamond. The growth rate of the diamond can be from about 20-100 μm/h.
B01J 3/06 - Procédés utilisant des hyper-pressions, p. ex. pour la formation de diamantsAppareillage approprié, p. ex. moules ou matrices
B01J 3/08 - Application d'ondes de choc à des réactions chimiques ou pour modifier la structure cristalline des substances
C30B 23/00 - Croissance des monocristaux par condensation d'un matériau évaporé ou sublimé
C30B 25/00 - Croissance des monocristaux par réaction chimique de gaz réactifs, p. ex. croissance par dépôt chimique en phase vapeur
C30B 28/12 - Production de matériaux polycristallins homogènes de structure déterminée directement à partir de l'état gazeux
C30B 28/14 - Production de matériaux polycristallins homogènes de structure déterminée directement à partir de l'état gazeux par réaction chimique de gaz réactifs
The method of improving the optical properties of single crystal CVD diamond which comprises annealing the crystals at a temperature of up to 2200°C and a pressure below 300 torr.
C23C 16/511 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement au moyen de décharges électriques utilisant des décharges à micro-ondes
The present invention identifies a novel family of kinases regulated by brassinosteroids, referred to as BRKs (brassinosteroid regulated kinases) or BSKs (brassinosteroid signaling kinases). The present invention provides methods for modulating the response of a plant cell to a brassinosteroid using BRKs.
A01H 1/00 - Procédés de modification des génotypes
A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique
C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux
45.
BRASSINOSTEROID REGULATED KINASES (BRKS) THAT MEDIATE BRASSINOSTEROID SIGNAL TRANSDUCTION AND USES THEREOF
The present invention identifies a novel family of kinases regulated by brassinosteroids, referred to as BRKs (brassinosteroid regulated kinases) or BSKs (brassinosteroid signaling kinases). The present invention provides methods for modulating the response of a plant cell to a brassinosteroid using BRKs.
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
The invention provides a cartridge (10) containing an addressable array (36) for detecting the presence of one or more target analytes in a fluid sample. The cartridge (10) comprises (i) a housing (12a, 12b) defining a sample inlet (48), an optical cell, an outlet, a first conduit in fluidic communication with the sample inlet and the optical cell, and a second conduit in fluidic communication with the outlet and the optical cell, (ii) an addressable array (36) disposed within the optical cell; and (iii) a reagent dried upon a fluid contacting surface of at least one of the sample inlet and the first conduit, such that, when a fluid sample is applied to the fluid inlet, the fluid sample mobilizes and transports the reagent to the optical cell. The invention also provides a method of detecting one or more analytes in a fluid sample of interest.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G01N 33/558 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet utilisant la diffusion ou la migration de l'anticorps ou de l'antigène
The invention relates to a single crystal boron doped CVD diamond that has a toughness of at least about 22 MPa m1/2. The invention further relates to a method of manufacturing single crystal boron doped CVD diamond. The growth rate of the diamond can be from about 20-100 μm/h.
C04B 35/495 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base d'oxydes de vanadium, de niobium, de tantale, de molybdène ou de tungstène ou de leurs solutions solides avec d'autres oxydes, p. ex. vanadates, niobates, tantalates, molybdates ou tungstates
49.
X-RAY-INDUCED DISSOCIATION OF H2O AND FORMATION OF AN O2-H2 ALLOY AT HIGH PRESSURE
A novel molecular alloy of O2 and H2 and a method of producing such a molecular alloy are provided. When subjected to high pressure and extensive x-radiation, H2O molecules cleaved, forming O-O and H-H bonds. In the method of the present invention, the O and H framework in ice VII was converted into a molecular alloy of O2 and H2. X-ray diffraction, x-ray Raman scattering, and optical Raman spectroscopy demonstrate that this crystalline solid differs from previously known phases.
The present invention relates to method of improving the optical properties of diamond at low pressures and more specifically to a method of producing a CVD diamond of a desired optical quality which includes growing CVD diamond and raising the temperature of the CVD diamond from about 1400 °C to about 2200 °C at a pressure of from about 1 to about 760 torr outside the diamond stability field in a reducing atmosphere for a time period of from about 5 seconds to about 3 hours.
The present invention provides methods for detecting and monitoring metabolite concentrations, which comprise detection and measurement of Fluorescence Resonance Energy Transfer upon ligand binding. The methods of the present invention are useful for real time monitoring of changes in metabolite levels in living cell cultures.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
This invention relates to partially ordered and ordered oxynitride perovskites of the general formula ABO2N that are polar insulators. A comprises one or more cations or set of cations that sit in sites derived from the A-site in the perovskite structure. B comprises one ore more cations or set of cations that sit in sites derived from the B-site in the perovskite structure. C comprises oxygen, O, with optionally some nitrogen, N, and D comprises N, with optionally some O. The total valence of the cations A + B is equal to the total valence of the anions 2 C + D. Also disclosed are methods of producing such oxynitride perovskites and uses of such oxynitride perovskites.
H01B 1/08 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisésEmploi de matériaux spécifiés comme conducteurs composés principalement d'autres substances non métalliques oxydes
53.
TRP/HIS EXCHANGE AND KYNURENINE INDUCED TRP TRANSPORT
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (USA)
Inventeur(s)
Kaper, Thijs
Platten, Michael, J.
Steinman, Lawrence
Frommer, Wolf
Abrégé
The present invention provides methods for detecting changes in tryptophan concentrations in a cell and methods for identifying agents that modulate cellular tryptophan concentrations. In particular, the present invention provides methods for detecting cellular exchange between tryptophan and kynurenine, and methods for identifying agents that modulate this exchange. The present invention also provides methods for treating a disease associated with immunosuppression in a subject in need thereof. In particular,. the present invention is directed toward a method of treating a disease associated with immunosuppression comprising contacting the disease with an agent that modulates cellular Trp/kynurenine exchange. Furthermore, the present invention provides methods for identifying an agent that modulates an immunosuppression.
A single-crystal CVD diamond produced with a method wherein the temperature of the diamond growth surface is in the range of 900 - 1400°C and wherein the diamond is mounted in a heat sink. The diamond is grown by a microwave plasma CVD, in a deposition chamber under 150 torr, wherein the CH4 is over 8% per unit of H2. Said diamond can be used as a heat sink for a laser. Another use, is as a frequency converter, as a 씟(3) nonlinear crystalline material for Raman laser converters comprising single crystal diamond.
The present invention provides systems and methods to automatically analyze Landsat satellite data of forests. The present invention can easily be used to monitor any type of forest disturbance such as from selective logging, agriculture, cattle ranching, natural hazards (fire, wind events, storms), etc. The present invention provides a large-scale, high-resolution, automated remote sensing analysis of such disturbances.
4. The method of the invention can produce diamonds larger than 10 carats. Growth rates using the method of the invention can be greater than 50 μm/hour.
The invention encompasses methods for improving the level and/or suslainability of expression for a target nucleic acid in a eukaryotic cell comprising: (a) modifying the target nucleic acid to introduce or to comprise signals that limit or constrain the positions of nucleosome cores, and (b) introducing the modified target nucleic acid into the eukaryotic cell, wherein the modified target nucleic acid has improved levels and/ or sustainability of expression compared to original unmodified nucleic acid.
C07H 21/02 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le ribosyle comme radical saccharide
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
C12N 15/00 - Techniques de mutation ou génie génétiqueADN ou ARN concernant le génie génétique, vecteurs, p. ex. plasmides, ou leur isolement, leur préparation ou leur purificationUtilisation d'hôtes pour ceux-ci
A01N 43/04 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome
A01N 63/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des micro-organismes, des virus, des champignons microscopiques, des animaux ou des substances produites par, ou obtenues à partir de micro-organismes, de virus, de champignons microscopiques ou d'animaux, p. ex. enzymes ou produits de fermentation
A01N 65/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux contenant du matériel provenant d'algues, de lichens, de bryophytes, de champignons multicellulaires ou de plantes, ou leurs extraits
A61K 31/70 - Hydrates de carboneSucresLeurs dérivés
59.
NEW DIAMOND USES/APPLICATIONS BASED ON SINGLE-CRYSTAL CVD DIAMOND PRODUCED AT RAPID GROWTH RATE
The present invention is directed to new uses and applications for colorless, single- crystal diamonds produced at a rapid growth rate. The present invention is also directed to methods for producing single crystal diamonds of varying color at a rapid growth rate and new uses and applications for such single-crystal, colored diamonds.
G11B 5/66 - Supports d'enregistrement caractérisés par l'emploi d'un matériau spécifié comportant uniquement le matériau magnétique, sans produit de liaison les supports d'enregistrement étant constitués par plusieurs couches magnétiques
B28D 5/04 - Travail mécanique des pierres fines, pierres précieuses, cristaux, p. ex. des matériaux pour semi-conducteursAppareillages ou dispositifs à cet effet par outils autres que ceux du type rotatif, p. ex. par des outils animés d'un mouvement alternatif
60.
MULTIMERIC BIOSENSORS AND METHODS OF USING THE SAME
Multimeric tryptophan biosensors are disclosed, which comprise tryptophan-binding domains conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon tryptophan binding. Such biosensors are useful for real time monitoring of tryptophan metabolism in living cells.
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
C12N 1/00 - Micro-organismes, p. ex. protozoairesCompositions les contenantProcédés de culture ou de conservation de micro-organismes, ou de compositions les contenantProcédés de préparation ou d'isolement d'une composition contenant un micro-organismeLeurs milieux de culture
C12N 15/00 - Techniques de mutation ou génie génétiqueADN ou ARN concernant le génie génétique, vecteurs, p. ex. plasmides, ou leur isolement, leur préparation ou leur purificationUtilisation d'hôtes pour ceux-ci
A01K 67/00 - Élevage ou obtention d'animaux, non prévus ailleursNouvelles races ou races modifiées d'animaux
A01H 9/00 - Ptéridophytes, p. ex. fougères, lycopodes, prêles
C07K 14/00 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
Sucrose biosensors are disclosed, which comprise a sucrose binding domain conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon sucrose binding. Such biosensors are useful for real time monitoring of sucrose metabolism in living cells.
Methods of avoiding repeat- and homology-induced silencing of transgenes are disclosed, in which trangene sequences are genetically altered to reduce the affects of gene silencing. FRET biosensors containing such genetic alterations for improved expression in cell lines and in vivo are disclosed.
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
C12N 15/00 - Techniques de mutation ou génie génétiqueADN ou ARN concernant le génie génétique, vecteurs, p. ex. plasmides, ou leur isolement, leur préparation ou leur purificationUtilisation d'hôtes pour ceux-ci
A01K 67/00 - Élevage ou obtention d'animaux, non prévus ailleursNouvelles races ou races modifiées d'animaux
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C07K 14/00 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
63.
PHOSPHATE BIOSENSORS AND METHODS OF USING THE SAME
Phosphate biosensors are disclosed, which comprise a phosphate binding domain conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon phosphate binding. Such biosensors are useful for real time monitoring of phosphate metabolism in living cells.
C07H 21/02 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le ribosyle comme radical saccharide
brevets
