Abrégé

The present invention relates to iota-carrageenan for use as a main or sole active ingredient in an aqueous pharmaceutical composition for the prevention or treatment of non-viral non-allergic clinically relevant eye conditions affecting at least one of mucosal tissues at or around an individual's eye, an eye surface, corneal tissue, and fluid inside the eye, said clinically relevant eye conditions selected from the group consisting of increased intraocular pressure, non- allergic and non-viral conjunctivitis, irritations caused by airborne particulate matter other than allergens, and late complications of non-viral and non-allergic conjunctivitis selected from the group consisting of corneal opacities, subepithelial infiltrates, and formation of ocular pseudomembranes.

Classes IPC  ?

• A61K 31/731 - Carraghénanes
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61P 27/04 - Larmes artificiellesSolutions d'irrigation
• A61P 27/06 - Agents antiglaucomateux ou myotiques
• A61P 27/14 - Décongestionnants ou antiallergiques

Abrégé

Disclosed is a spraying device for nasal or buccal delivery of a buffered aqueous composition comprising solubilized budesonide, which has improved long-term storage stability and reduced amounts of impurities, the buffer adjusted to pH 4 to 5, wherein budesonide is dissolved at a concentration of at least 100 /vg/mL, wherein the composition is free of metal ions and packed into a metal-free first containment closed with a spray pump system packaged into a sealed oxygen-impermeable, oxygen-free second containment, and wherein the composition after storage at 25 °C over a period of 1 2 months contains at least 90%, preferably at least 95 %, of the nominal starting concentration of solubilized budesonide, and no more than 1 %, relative to the budesonide concentration, of total impurities. The invention further relates to the composition for use as a medicament in the treatment of inflammatory diseases or conditions.

Classes IPC  ?

• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/08 - Solutions
• A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
• A61K 47/18 - AminesAmidesUréesComposés d’ammonium quaternaireAcides aminésOligopeptides ayant jusqu’à cinq acides aminés
• A61K 47/12 - Acides carboxyliquesLeurs sels ou anhydrides
• A61K 35/06 - Huiles minérales, p. ex. huiles paraffiniques ou aromatiques basées sur des hydrocarbures aromatiques
• A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
• A61M 11/00 - Pulvérisateurs ou vaporisateurs spécialement destinés à des usages médicaux
• A61K 31/58 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes contenant des hétérocycles, p. ex. danazol, stanozolol, pancuronium ou digitogénine
• A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
• A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
• A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes

Abrégé

Sulphated polysaccharides for use as an antiviral active ingredient in an antiviral effective amount in a pharmaceutical composition or medicament for the prophylactic or therapeutic intervention of a SARS-CoV-2 infection in a human individual or non-human animal.

Classes IPC  ?

• A61K 31/737 - Polysaccharides sulfatés, p. ex. sulfate de chondroïtine, sulfate de dermatane
• A61P 31/14 - Antiviraux pour le traitement des virus ARN

Produits et services

Cosmetics, cosmetics with added vitamins for non-medical purposes Pharmaceutical and veterinary preparations, namely, anti-inflammatory and antiviral preparations based on carrageenan or seaweed exctracts, for use in human and veterinary medicine; dietetic substances, namely, nutritional supplements comprising carrageenan or seaweed extract, adapted for medical use; enzyme preparations for medical and pharmaceutical purposes, cultures of marine organisms and microorganisms; sea salt; sea anemones in processed form for use as nutritional supplements, all aforementioned goods for medical purposes

Abrégé

The present invention relates to sulphated polysaccharides for use as an antiviral active ingredient in an antiviral effective amount in a pharmaceutical composition or medicament for the prophylactic or therapeutic intervention of a SARS-CoV-2 infection in a human individual or non-human animal.

Classes IPC  ?

• A61K 31/731 - Carraghénanes
• A61P 31/14 - Antiviraux pour le traitement des virus ARN

Abrégé

Quillaya saponaria extract to the aqueous solvent in an amount sufficient to trigger the formation of micelles, wherein in a first step the hydrophobic organic compound is pre-dissolved in an organic solvent, and in a second step the organic solvent comprising the pre-dissolved compound is admixed to the aqueous solvent, whereby at least a part of the insoluble or slightly soluble hydrophobic organic compound gets solubilized and dissolved in the aqueous solvent, yielding an aqueous composition having an increased concentration of said organic compound dissolved therein. Also indicated are pharmaceutical or cosmetic compositions including a water-insoluble or slightly water-soluble organic compound dissolved in an aqueous solvent at substantially increased concentrations.

Classes IPC  ?

• A61K 8/60 - SucresLeurs dérivés
• A61K 9/107 - Émulsions
• A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
• A61K 47/18 - AminesAmidesUréesComposés d’ammonium quaternaireAcides aminésOligopeptides ayant jusqu’à cinq acides aminés
• A61K 8/42 - Amides
• A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
• A61K 47/46 - Ingrédients de constitution indéterminée ou leurs produits de réaction, p. ex. peau, os, lait, fibre de coton, coquille d’œuf, fiel de bœuf ou extraits de plante
• A61K 8/9789 - Magnoliopsida [dicotylédones]
• A61K 31/58 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes contenant des hétérocycles, p. ex. danazol, stanozolol, pancuronium ou digitogénine
• A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
• A61K 31/56 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes
• A61K 38/13 - Cyclosporines
• A61K 31/138 - Aryloxyalkylamines, p. ex. propranolol, tamoxifène, phénoxybenzamine
• A61K 31/337 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à quatre chaînons, p. ex. taxol
• A61K 8/02 - Cosmétiques ou préparations similaires pour la toilette caractérisés par une forme physique particulière
• A61K 8/34 - Alcools
• A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
• A61K 31/12 - Cétones
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61Q 19/00 - Préparations pour les soins de la peau
• A61K 8/67 - Vitamines

Abrégé

A pharmaceutical composition has a stuffy nose deblocking activity. The composition includes a hyperosmolar aqueous solution of a non-ionic osmolality adjusting agent, optionally in combination with an ionic osmolality adjusting agent, wherein the composition further includes iota-carrageenan and/or kappa-carrageenan as an active antiviral ingredient in an antivirally effective amount, with the proviso that the composition in its ready-for-use formulation contains no more than 0-1.5% w/v of the ionic osmolality adjusting agent. The composition is useful for deblocking a stuffy nose and for prophylactic or therapeutic intervention of a number of viral infections of the upper respiratory tract.

Classes IPC  ?

• A61K 33/14 - Chlorures des métaux alcalinsChlorures des métaux alcalino-terreux
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 31/731 - Carraghénanes
• A61K 9/08 - Solutions
• A61K 31/047 - Composés hydroxylés, p. ex. alcoolsLeurs sels, p. ex. alcoolates ayant plusieurs groupes hydroxyle, p. ex. sorbitol
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
• A61K 9/12 - AérosolsMousses
• A61P 31/14 - Antiviraux pour le traitement des virus ARN
• A61P 11/02 - Agents rhinologiques, p. ex. décongestionnants

Produits et services

Disinfectants and antiseptics; Chemical preparations for sanitary purposes; Hygienic preparations for veterinary use; Sanitary preparations for medical purposes; Sanitary tampons; Panty liners [sanitary]; Pantyliners; Sanitary towels; Feminine hygiene products; Sanitary wear; Absorbent sanitary articles; Nasal decongestants; Decongestants; Adjuvants for medical purposes; Alginates for pharmaceutical purposes; Anti-allergy sprays; Allergy medication; Antibiotics for human use; Antibiotics for veterinary use; Anti-bacterial preparations; Antibacterial pharmaceuticals; Antibiotic creams; Antibiotic ointments; Mixed antibiotic preparations; Antibiotics in the form of lotions; Antibiotic tablets; Anti-microbial preparations; Anti-viral agents; Topical antivirals; Medicines for human purposes; Medicines for veterinary purposes; Allergy relief medication; Eye lotions for medical use; Eye ointment for medical use; Chemico-pharmaceutical preparations; Chemical adjuvants for medical purposes; Chemical preparations for pharmaceutical purposes; Elixirs for relieving chills; Elixirs for preventing chills; Elixirs for relieving asthma; Elixirs for preventing throat infections; Anti-inflammatory gels; Anti-inflammatories; Anti-inflammatory sprays; Anti-inflammatory ointments; Moist wipes impregnated with a pharmaceutical lotion; Throat lozenges; Hand creams for medical use; Antitussives; Anti-cough drops; Human vaccine preparations; Cough mixtures; Cough tablets; Vaccines against flu; Vaccine adjuvants; Anti-infective products for veterinary use; Topical anti-infective substances for the treatment of infections of the eye; Inhaled pharmaceutical preparations for the treatment of respiratory diseases and disorders; Inhalants; Irish moss for medical purposes; Allergy capsules; Chewing gum for medical purposes; Artificial tears; Lotions for pharmaceutical purposes; Solutions for medical use in washing the nasal passages; Medicated creams; Creams (Medicated -) for the lips; Therapeutic creams [medical]; Medicinal ointments; Medicated throat sprays; Medicated lip balm; Medicated lip care preparations; Medicated lotions; Medicated mouth spray; Medicated nasal spray preparations; Medicinal preparations for the treatment of infectious diseases; Medicated lozenges; Medicinal preparations and substances; Medicinal sprays; Medicated ointments for application to the skin; Impregnated pads containing medicated preparations; Tissues impregnated with pharmaceutical lotions; Preparations for ocular lubrication; Cold sore treatment preparations; Mouth sprays for medical use; Mouthwashes [gargles] for medical purposes; Nasal cleaning preparations for medical purposes; Nasal sprays for medical purposes; Nasal spray for the treatment of allergies; Nasal rinse; Nose drops; Nasal drops for the treatment of allergies; Ophthalmologic preparations; Topical ophthalmic anti-infective substances for the treatment of infections; Ocular pharmaceuticals; Plant and herb extracts for medicinal use; Plant extracts for pharmaceutical purposes; Pharmaceutical drugs; Pharmaceutical creams; Pharmaceutical products for ophthalmological use; Pharmaceutical products for treating respiratory diseases; Pharmaceutical products for the treatment of infectious diseases; Pharmaceutical preparations for treating allergic rhinitis; Pharmaceutical cold preparations; Pharmaceutical antiallergic preparations and substances; Pharmaceutical lipsalves; Pharmaceutical cough preparations; Pharmaceutical preparations and substances with anti-inflammatory properties; Pharmaceutical preparations for treating asthma; Pharmaceutical preparations for the treatment of eye diseases and conditions; Pharmaceutical preparations for the treatment of viral diseases; Pharmaceutical preparations for treating allergies; Pharmaceutical preparations for the treatment of inflammatory disorders; Pharmaceutical preparations for use in ophthalmology; Pharmaceutical preparations for the prevention of inflammatory disorders; Pharmaceutical preparations for the prevention of disorders of the respiratory system; Pharmaceutical preparations for the prevention of diseases of the respiratory system; Pharmaceutical preparations for the treatment of inflammatory diseases; Pharmaceutical preparations for the prevention of inflammatory diseases; Pharmaceutical preparations for the prevention of allergies; Pharmaceutical preparations for the prevention of ocular disorders; Pharmaceutical preparations for the prevention of ocular diseases; Pharmaceutical preparations for inhalers; Pharmaceutical preparations for the treatment of diseases caused by bacteria; Anti-infectives; Preparations for the treatment of asthma; Compounds for treating respiratory diseases; Preparations for treating colds; Medicine cases, portable, filled; Non-prescription medicines; Ointments for pharmaceutical purposes; Pain relief preparations; Syrups for pharmaceutical purposes; Decongestant nasal sprays; Allergy tablets; Cough pastilles for medical use; Tinctures for medical purposes; Viral vaccines; Virucides; Transdermal patches for medical treatment; Antiseptic cotton; Eye bandages for medical use; Disinfectant swabs; Disinfectant dressings; Impregnated medicated pads; Moist paper hand towels impregnated with a pharmaceutical lotion; Sticking plasters for medical use; Impregnated antiseptic wipes; Impregnated medicated swabs; Cotton wool for medical use; Tampons for medical purposes; Transdermal patches; Wadding for medical purposes; Cotton wool for pharmaceutical purposes; Wipes for medical use; Eye drops; Biochemical preparations for medical use; Biochemical preparations for veterinary use; Chemical preparations for medical purposes; Chemical preparations for veterinary purposes; Antipyretic preparations; Vaccines; Impregnated medicated wipes; Lotions for veterinary purposes; Medicated eye-washes; Pharmaceutical preparations for veterinary use; Sanitary preparations for veterinary use; Veterinary preparations and substances.

Abrégé

The present invention relates to a pharmaceutical composition having a stuffy nose deblocking activity, characterized in that the composition comprises a hyperosmolar aqueous solution of a non-ionic osmolality adjusting agent, optionally in combination with an ionic osmolality adjusting agent, wherein the composition further comprises iota-carrageenan and/or kappa-carrageenan as an active antiviral ingredient in an antivirally effective amount, with the proviso that the composition in its ready-for-use formulation contains no more than 1.5% w/v of the ionic osmolality adjusting agent. The composition is useful for deblocking a stuffy nose and for prophylactic or therapeutic intervention of a number of viral infections of the upper respiratory tract.

Classes IPC  ?

• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61K 31/047 - Composés hydroxylés, p. ex. alcoolsLeurs sels, p. ex. alcoolates ayant plusieurs groupes hydroxyle, p. ex. sorbitol
• A61K 31/731 - Carraghénanes
• A61K 33/14 - Chlorures des métaux alcalinsChlorures des métaux alcalino-terreux
• A61P 11/02 - Agents rhinologiques, p. ex. décongestionnants
• A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus

Abrégé

A method of increasing the solubility of a water-insoluble or slightly water- soluble hydrophobic organic compound in an aqueous solvent comprises adding a saponin component selected from the group consisting of escin, glycyrrhizin, and Quillaya saponaria extract to the aqueous solvent in an amount sufficient to trigger the formation of micelles, wherein in a first step the hydrophobic organic compound is pre-dissolved in an organic solvent, whereupon in a second step the organic solvent comprising the pre-dissolved compound is admixed to the aqueous solvent; whereupon at least a part of the insoluble or slightly soluble hydrophobic organic compound gets solubilized and dissolved in the aqueous solvent, yielding an aqueous composition having an increased concentration of said organic compound dissolved therein. The invention also relates to pharmaceutical or cosmetic compositions comprising a water-insoluble or slightly water-soluble organic compound dissolved in an aqueous solvent at substantially increased concentrations.

Classes IPC  ?

• A61K 9/08 - Solutions
• A61K 31/58 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes contenant des hétérocycles, p. ex. danazol, stanozolol, pancuronium ou digitogénine
• A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine

Abrégé

Disclosed herein is a method of reducing the risk of a rhinovirus infection, the method includes administering to a subject a composition comprising iota-carrageenan in an antiviral effective amount as an active antiviral ingredient.

Classes IPC  ?

• A61K 36/02 - Algues
• A61K 31/731 - Carraghénanes

Abrégé

The present invention provides for the use of iota- and/or kappa-carrageenan for the manufacture of an antiviral pharmaceutical composition for the prophylaxis or treatment of a pathological condition or disease caused by or associated with an infection by a respiratory virus selected from the group consisting of orthomyxovirus, paramyxovirus, adenovirus and coronavirus. The present invention further provides for the use of fucoidan, in particular of high molecular weight fucoidan, for the manufacture of an antiviral pharmaceutical composition for the prophylaxis or treatment of a pathological condition or disease caused by or associated with an infection by a respiratory virus selected from the group consisting of orthomyxovirus and paramyxovirus.

Classes IPC  ?

• A61K 31/737 - Polysaccharides sulfatés, p. ex. sulfate de chondroïtine, sulfate de dermatane
• A61K 31/731 - Carraghénanes

Abrégé

A method for manufacturing an antiviral pharmaceutical composition for the prophylaxis or treatment of a rhinovirus infection that includes the utilization of iota-, kappa- or lambda-carrageenan or mixtures thereof.

Classes IPC  ?

• A61K 36/82 - Theaceae (famille du théier), p. ex. camélia

Produits et services

Enzyme preparations for use in cosmetics. Cosmetics, cosmetics with added vitamins for non-medical purposes. Pharmaceutical and veterinary preparations; dietetic substances adapted for medical use, enzyme preparations for medical and pharmaceutical purposes, cultures of marine organisms and microorganisms, sea salt, marine corals in processed form for pharmaceutical and medical purposes, sea anemones in processed form for pharmaceutical and medical purposes, all aforementioned goods for medical purposes.

Produits et services

Enzyme preparations for use in cosmetics. Cosmetics, cosmetics with added vitamins for non-medical purposes. Pharmaceutical and veterinary preparations; dietetic substances adapted for medical use, enzyme preparations for medical and pharmaceutical purposes, cultures of marine organisms and microorganisms, sea salt, marine corals in processed form for pharmaceutical and medical purposes, sea anemones in processed form for pharmaceutical and medical purposes, sponges in processed form for pharmaceutical and medical purposes, all aforementioned goods for medical purposes.