|
|
Résultats pour
 brevets
1.
|
THIENOPYRIDAZINE COMPOUNDS, THEIR PREPARATIONS, PHARMACEUTICAL COMPOSITIONS AND USES FOR TREATING CANCER
| Numéro de document |
02711629 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2009-01-07 |
| Date d'octroi |
2017-10-24 |
| Propriétaire |
- WU, ZHANGGUI (Chine)
- ZHE JIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY (Chine)
|
| Inventeur(s) |
Wu, Zhanggui
|
Abrégé
The present invention relates to thienopyridazine compounds of formula (I),
their
pharmaceutically acceptable salts or hydrates, wherein R1 and R2 are
independently
H or C1-4 alkyl, R3 is a saturated or unsaturated 5- or 6- membered ring
containing N,
S or O, or its optical isomers, R4 is a halophenyl monosubstituted or
disubstituted at
any position. The present invention provides the preparation methods of these
compounds, pharmaceutical compositions containing these compounds and the uses
of these compounds, particularly in treating cancer.
(See Formula I)
Classes IPC ?
- A61K 31/381 - Composés hétérocycliques ayant le soufre comme hétéro-atome d'un cycle ayant des cycles à cinq chaînons
- A61P 35/00 - Agents anticancéreux
- C07D 495/04 - Systèmes condensés en ortho
|
2.
|
HIGH-STABILITY DAPTOMYCIN COMPOSITION FOR INJECTION, AND PREPARATION METHOD THEREFOR AND USE THEREOF
| Numéro de document |
03206447 |
| Statut |
En instance |
| Date de dépôt |
2021-05-27 |
| Propriétaire |
- ZHEJIANG NOVUS PHARMACEUTICALS CO., LTD. (Chine)
- ZHEJIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY (Chine)
|
| Inventeur(s) |
- Yuan, Xiying
- Wang, Weibao
- Wu, Guofeng
- Ye, Lili
- Wu, Jiali
- Cai, Jingjing
- Pan, Yibin
- Zha, Juan
- Gao, Zhongming
- Sun, Qiming
- He, Yimin
- Wang, Zuoliang
- Ping, Jianhong
|
Abrégé
Disclosed are a high-stability daptomycin composition for injection, and a preparation method therefor. The daptomycin composition for injection comprises daptomycin and a pharmaceutically acceptable carrier, and the pharmaceutically acceptable carrier contains a divalent metal salt, a pH regulator, and an osmotic pressure regulator; and the molar ratio of daptomycin to divalent metal salt in the daptomycin composition for injection is 1: 1.0 to 1: 3.5. The composition can be used for preparing antibacterial drugs.
Classes IPC ?
- A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
- A61K 9/19 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres lyophilisées
- A61K 38/12 - Peptides cycliques
- A61K 47/02 - Composés inorganiques
- A61P 31/04 - Agents antibactériens
|
3.
|
A STABLE FAT-SOLUBLE ACTIVE INGREDIENT COMPOSITION, MICROCAPSULE AND PROCESS OF PREPARATION AND USE THEREOF
| Numéro de document |
03051023 |
| Statut |
En instance |
| Date de dépôt |
2018-01-19 |
| Date d'octroi |
2025-08-12 |
| Propriétaire |
- ZHEJIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY (Chine)
- ZHEJIANG MEDICINE CO., LTD. VITAMIN FACTORY (Chine)
|
| Inventeur(s) |
- Mao, Guoquan
- Zhu, Hongming
- Ma, Wenxin
- Liang, Zhiping
- Qian, Li
- Lubbe, Fritz Bernhard
- Hu, Siping
- Li, Chun
- Wen, Shanping
- Wang, Qinlan
- Kong, Huajuan
|
Abrégé
The present invention provides a stable fat-soluble active ingredient composition, microcapsule and process for preparation and use thereof. The fat-soluble active ingredient composition comprises tocopherol, vitamin C palmitate and a fat-soluble active ingredient; wherein the weight ratio of tocopherol to vitamin C palmitate is 2-8:1, the weight ratio of a combination of tocopherol with vitamin C palmitate to the fat-soluble active ingredient is 7-13:100. The present invention obtains a novel antioxidant composition without hidden dangers for improving the stability of the fat-soluble active ingredient by screening a combination of antioxidants and adjusting their proportion and dose.
Classes IPC ?
- A23B 2/771 - Composés organiques contenant des hétérocycles
- A61K 8/11 - Compositions encapsulées
- A61K 8/67 - Vitamines
- A61K 9/50 - Microcapsules
- A61K 47/22 - Composés hétérocycliques, p. ex. acide ascorbique, tocophérol ou pyrrolidones
- A61Q 19/00 - Préparations pour les soins de la peau
|
|