05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Pharmaceutical and veterinary preparations for the treatment of diseases or conditions of the respiratory system; pharmaceutical and veterinary preparations for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical and veterinary preparations for the alleviation or prevention of pain or inflammation; inhalers filled with powders for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical preparations, namely, powders for asthma inhalers; pharmaceutical preparations, namely, powders for transdermal injection for the alleviation or prevention of pain, for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical and veterinary preparations for oral ingestion for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical and veterinary preparations for topical administration for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical and veterinary preparations for erectile dysfunction; pharmaceutical and veterinary preparations for chronic obstructive pulmonary disease; pharmaceutical and veterinary preparations for premature ejaculation; pharmaceutical and veterinary preparations for cystic fibrosis; pharmaceutical and veterinary preparations for female sexual dysfunction; medicaments for migraine; pharmaceutical and veterinary preparations for asthma Inhalers for medical purposes, sold empty; metered dose inhalers for medical purposes, sold empty; active dry powder inhalers for medical purposes, sold empty; passive dry powder inhalers for medical purposes, sold empty; nebulisers for respiration therapy; respirators for artificial respiration and parts and fittings for all the aforesaid goods
05 - Produits pharmaceutiques, vétérinaires et hygièniques
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Pharmaceutical and veterinary preparations for the treatment of diseases or conditions of the respiratory system; pharmaceutical and veterinary preparations for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynaecological conditions; pharmaceutical and veterinary preparations for the alleviation or prevention of pain or inflammation; inhalers filled with powders for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynaecological conditions; pharmaceutical preparations, namely, powders for asthma inhalers; pharmaceutical preparations, namely, powders for transdermal injection for the alleviation or prevention of pain, for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical and veterinary preparations for oral ingestion for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical and veterinary preparations for topical administration for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; medicaments for inhalation therapy; pharmaceutical preparations, namely, pulmonary delivery compositions for use in facilitating the inhalation of pharmaceuticals, namely, drug delivery agents consisting of compounds that facilitate delivery by inhalation of a wide range of pharmaceuticals; medicaments for the treatment of erectile dysfunction; medicaments for the treatment of chronic obstructive pulmonary disease; medicaments for the treatment of premature ejaculation; medicaments for the treatment of cystic fibrosis; medicaments for the treatment of female sexual dysfunction; medicaments for the treatment of migraines; medicaments for the treatment of asthma; all of the above goods not for use in the dental field Custom manufacture of pharmaceuticals; Consulting services in the field of pharmaceutical formulation, development of medical applications for drugs and pharmaceutical formulations, drug design, drug formulation, pharmaceutical formulation, and development of pharmaceutical formulations Surgical, medical, and veterinary apparatus, instruments and parts and fittings therefor, namely, drug delivery devices and parts and fittings therefor, namely, drug delivery systems being nebulizers for medical purposes; inhalers sold empty for medical or therapeutic purposes and parts and fittings therefor; active dry powder inhalers sold empty for medical or therapeutic purposes and parts and fittings therefor; passive dry powder inhalers sold empty for medical or therapeutic purposes and parts and fittings therefor; nebulisers for inhalation therapy, namely, respiration therapy, and parts and fittings therefor; inhaler devices sold empty for medical or therapeutic purposes and parts and fittings therefor; all of the above goods not for use in the dental field Scientific research and technological services, namely, research, design, analysis, and testing, in the field of pharmaceuticals and drug delivery systems, and drug delivery systems and devices; Scientific research and technological services, namely, research in the field of medicine; industrial analysis and research services in the fields of drug delivery systems and devices; research services in the fields of medicine; pharmaceutical research services; pharmaceutical products development services; device and product safety testing services;
3.
COMPOSITIONS FOR THE TREATMENT OF A RESPIRATORY CONDITION
The present disclosure relates to the administration of a composition comprising an interferon, azithromycin and chloroquine for the treatment of respiratory conditions.
Systems and methods are disclosed for simultaneously jet milling and conditioning particulate material comprising a grinding chamber and an aerosol generator arranged to supply liquid aerosol into the grinding chamber. A composition made by this method is also disclosed.
B02C 19/06 - Appareils utilisant un courant de fluides
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
B02C 23/18 - Addition de fluide, dans un but autre que celui de broyer ou de désagréger par l'énergie du fluide
5.
COMPOSITIONS FOR THE TREATMENT OF A RESPIRATORY CONDITION
The present disclosure relates to the administration of a composition comprising an interferon, azithromycin and chloroquine for the treatment of respiratory conditions.
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A PEGylated polymer is disclosed according to Formula 1 wherein n is any integer from 4 to 200 monomers, and R is a polymer chain comprising a 4 to 200-monomer moiety.
A61K 47/60 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique macromoléculaire, p. ex. une molécule oligomérique, polymérique ou dendrimérique obtenu par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyurées ou polyuréthanes le composé organique macromoléculaire étant un oligomère, un polymère ou un dendrimère de polyoxyalkylène, p. ex. PEG, PPG, PEO ou polyglycérol
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
C08G 69/42 - Polyamides contenant des atomes autres que le carbone, l'hydrogène, l'oxygène et l'azote
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical substances and products for use in the manufacture
of medical preparations. Medical preparations; pharmaceutical preparations for
medical purposes; biological preparations for medical
purposes; pharmaceutical preparations formulated for
pulmonary delivery via inhalation; pharmaceutical
preparations for the prevention or treatment of diseases or
conditions of the respiratory and cardiovascular systems. Medical apparatus and instruments; drug delivery devices;
inhalers; metered dose inhalers; active dry powder inhalers;
passive dry powder inhalers; nebulisers for respiration
therapy; respirators for artificial respiration; parts and
fittings for all the aforesaid goods. Scientific research, development, design, analysis, testing
and investigation relating to medical preparations and drug
delivery devices; medical research; research relating to
drug delivery devices; research relating to drug
formulation; pharmaceutical development; preparation and
formulation of pharmaceuticals; device and product testing.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical substances and products for use in the manufacture
of medical preparations. Medical preparations; pharmaceutical preparations for
medical purposes; biological preparations for medical
purposes; pharmaceutical preparations formulated for
pulmonary delivery via inhalation; pharmaceutical
preparations for the prevention or treatment of diseases or
conditions of the respiratory and cardiovascular systems. Medical apparatus and instruments; drug delivery devices;
inhalers; metered dose inhalers; active dry powder inhalers;
passive dry powder inhalers; nebulisers for respiration
therapy; respirators for artificial respiration; parts and
fittings for all the aforesaid goods. Scientific research, development, design, analysis, testing
and investigation relating to medical preparations and drug
delivery devices; medical research; research relating to
drug delivery devices; research relating to drug
formulation; pharmaceutical development; preparation and
formulation of pharmaceuticals; device and product testing.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Chemical substances and products for use in the manufacture of medical preparations for treating respiratory diseases.
(2) Medical preparations for treating respiratory diseases; pharmaceutical preparations for treating respiratory diseases; biological preparations for treating respiratory diseases; pharmaceutical preparations formulated for pulmonary delivery via inhalation for treating respiratory diseases; pharmaceutical preparations for the prevention and treatment of diseases and conditions of the respiratory and cardiovascular systems
(3) Medical apparatus and instruments, namely, inhalers, metered dose inhalers, active dry powder inhalers and passive dry powder inhalers, and parts and fittings for all the aforesaid goods; nebulisers for respiration therapy, and parts and fittings for all the aforesaid goods; respirators for artificial respiration; and parts and fittings for all the aforesaid goods (1) Scientific research, development, design, analysis, testing and investigation relating to medical preparations and drug delivery devices; medical research; research relating to drug delivery devices namely for treating respiratory diseases; research relating to drug formulation for respiratory diseases; pharmaceutical development; preparation and formulation of pharmaceuticals for treating respiratory diseases; medical devices and product testing in the field of pharmaceutical preparations and drug delivery devices
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Chemical substances and products for use in the manufacture of medical preparations for treating respiratory diseases
(2) Medical preparations for treating respiratory diseases; pharmaceutical preparations for treating respiratory diseases; biological preparations for treating respiratory diseases; pharmaceutical preparations formulated for pulmonary delivery via inhalation for treating respiratory diseases; pharmaceutical preparations for the prevention or treatment of diseases or conditions of the respiratory and cardiovascular systems
(3) Medical apparatus and instruments, namely, inhalers, metered dose inhalers, active dry powder inhalers and passive dry powder inhalers, and parts and fittings for all the aforesaid goods; nebulisers for respiration therapy, and parts and fittings for all the aforesaid goods; respirators for artificial respiration and parts and fittings for all the aforesaid goods (1) Scientific research, development, design, analysis, testing and investigation relating to medical preparations and drug delivery devices; medical research; research relating to drug delivery devices namely for treating respiratory diseases; research relating to drug formulation for respiratory diseases; pharmaceutical development; preparation and formulation of pharmaceuticals for treating respiratory diseases; medical devices and product testing in the field of pharmaceutical preparations and drug delivery devices
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical additives for use in the manufacture of medical preparations Medical preparations for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynaecological conditions; pharmaceutical preparations for medical purposes for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynaecological conditions; biological preparations for medical purposes for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynaecological conditions; pharmaceutical preparations for treating pulmonary diseases via inhalation; pharmaceutical preparations for the prevention and treatment of diseases and conditions of the respiratory and cardiovascular systems Medical apparatus and instruments, namely inhalers; drug delivery devices, namely inhalers; inhalers for medical use; metered dose inhalers for medical use; active dry powder inhalers for medical use; passive dry powder inhalers for medical use; nebulisers for respiration therapy; respirators for artificial respiration; component parts and fittings for all the aforesaid goods Scientific research relating to medical preparations and drug delivery devices; development and design medical preparations and drug delivery devices; analysis, and investigation in the form of testing of medical preparations and drug delivery devices; medical research; research relating to drug delivery devices; research relating to drug formulation; pharmaceutical development
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical additives for use in the manufacture of medical preparations Medical preparations for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynaecological conditions; pharmaceutical preparations for medical purposes for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynaecological conditions; biological preparations for medical purposes for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynaecological conditions; pharmaceutical preparations for treating pulmonary diseases via inhalation; pharmaceutical preparations for the prevention and treatment of diseases and conditions of the respiratory and cardiovascular systems Medical apparatus and instruments, namely inhalers; drug delivery devices, namely inhalers; inhalers for medical use; metered dose inhalers for medical use; active dry powder inhalers for medical use; passive dry powder inhalers for medical use; nebulisers for respiration therapy; respirators for artificial respiration; component parts and fittings for all the aforesaid goods Scientific research relating to medical preparations and drug delivery devices; development and design medical preparations and drug delivery devices; analysis, and investigation in the form of testing of medical preparations and drug delivery devices; medical research; research relating to drug delivery devices; research relating to drug formulation; pharmaceutical development
13.
Method for making a micronized dry powder formulation of glycopyrrolate and magnesium stearate
Methods are disclosed for simultaneously jet milling and conditioning particulate glycopyrrolate and magnesium stearate using a milling gas having humidity between 5% and 30% Relative Humidity in the grinding chamber of a jet mill, the jet mill is configured with a humidifier arranged to supply humidity into the grinding chamber. A composition and formulation comprising physically stable micronized composite glycopyrrolate particles made by this method is also disclosed.
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
A61K 31/573 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne à deux atomes de carbone, p. ex. prégnane ou progestérone substitués en position 21, p. ex. cortisone, dexaméthasone, prednisone ou aldostérone
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical substances and products for use in the manufacture of medical preparations. Medical preparations; pharmaceutical preparations for medical purposes; biological preparations for medical purposes; pharmaceutical preparations formulated for pulmonary delivery via inhalation; pharmaceutical preparations for the prevention or treatment of diseases or conditions of the respiratory and cardiovascular systems. Medical apparatus and instruments; drug delivery devices; inhalers; metered dose inhalers; active dry powder inhalers; passive dry powder inhalers; nebulisers for respiration therapy; respirators for artificial respiration; parts and fittings for all the aforesaid goods. Scientific research, development, design, analysis, testing and investigation relating to medical preparations and drug delivery devices; medical research; research relating to drug delivery devices; research relating to drug formulation; pharmaceutical development; preparation and formulation of pharmaceuticals; device and product testing.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical substances and products for use in the manufacture of medical preparations. Medical preparations; pharmaceutical preparations for medical purposes; biological preparations for medical purposes; pharmaceutical preparations formulated for pulmonary delivery via inhalation; pharmaceutical preparations for the prevention or treatment of diseases or conditions of the respiratory and cardiovascular systems. Medical apparatus and instruments; drug delivery devices; inhalers; metered dose inhalers; active dry powder inhalers; passive dry powder inhalers; nebulisers for respiration therapy; respirators for artificial respiration; parts and fittings for all the aforesaid goods. Scientific research, development, design, analysis, testing and investigation relating to medical preparations and drug delivery devices; medical research; research relating to drug delivery devices; research relating to drug formulation; pharmaceutical development; preparation and formulation of pharmaceuticals; device and product testing.
The invention relates to a polymorphic form of (S)-3-(3-(1-methyl-2-oxo-5-(pyrazolo[1,5-a]pyridine-3-yl)-1H-imidazo[4,5-b]pyridine-3(2H)-yl)piperidin-1-yl)-3-oxopropanenitrile and use as a therapeutic agent for the treatment of respiratory diseases.
C07D 519/00 - Composés hétérocycliques contenant plusieurs systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un système carbocyclique commun non prévus dans les groupes ou
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
The present invention concerns a method for making an inhaled pharmaceutical composition with improved powder handling properties comprising a stearate, a method of preparing such a composition, and the use of such a stearate in a composition when dispensed into a receptacle for use in a dry powder inhaler receptacle.
Methods are disclosed for simultaneously jet milling and conditioning particulate glycopyrrolate and magnesium stearate using a milling gas having humidity between 5% and 30% Relative Humidity in the grinding chamber of a jet mill, the jet mill is configured with a humidifier arranged to supply humidity into the grinding chamber. A composition and formulation comprising physically stable micronized composite glycopyrrolate particles made by this method is also disclosed.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
Systems and methods are disclosed for simultaneously jet milling and conditioning particulate material comprising a grinding chamber and an aerosol generator arranged to supply liquid aerosol into the grinding chamber. A composition made by this method is also disclosed.
B02C 19/06 - Appareils utilisant un courant de fluides
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
B02C 23/18 - Addition de fluide, dans un but autre que celui de broyer ou de désagréger par l'énergie du fluide
An inhalable powder composition comprises a) an antagonistic antibody which binds human IL-13, b) leucine and c) trehalose. The antibody may comprise a heavy chain, wherein the variable domain of the heavy chain comprises the sequence given in SEQ ID NO:3 and a light chain, wherein the variable domain of the light chain comprises the sequence given in SEQ ID NO:1. Also described is the use of such compositions in the treatment of asthma, as well as inhalers containing such compositions.
C07K 16/24 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des cytokines, des lymphokines ou des interférons
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A PEGylated polymer is disclosed according to Formula 1 wherein n is any integer from 4 to 200 monomers, and R is a polymer chain comprising a 4 to 200‐monomer moiety.
A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
C08G 69/40 - Polyamides contenant de l'oxygène sous forme de groupes éther
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
The invention relates to a polymorphic forms of (S)-3-(3-(1-methyl-2-oxo-5-(pyrazolo[1,5-a]pyridine-3-yl)-1H-imidazo[4,5-b]pyridine-3(2H)-yl)piperidin-1-yl)-3-oxopropanenitrile and their use as a therapeutic agent for the treatment of respiratory diseases.
C07D 519/00 - Composés hétérocycliques contenant plusieurs systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un système carbocyclique commun non prévus dans les groupes ou
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
The invention discloses spray-dried compositions for inhalation and methods for preparing such powder compositions. The compositions of the invention are produced by spray-drying taurine under conditions that (i) retain the physical and chemical stability of the composition during spray drying and upon storage, (ii) protect the powder composition from aggregation and (iii) provide particles suitable for aerosolization.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61K 31/58 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes contenant des hétérocycles, p. ex. danazol, stanozolol, pancuronium ou digitogénine
A61K 31/185 - AcidesLeurs anhydrides, halogénures ou sels, p. ex. acides du soufre, acides imidiques, hydrazoniques ou hydroximiques
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
A61K 31/439 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle le cycle formant une partie d'un système cyclique ponté, p. ex. quinuclidine
C07C 309/14 - Acides sulfoniques ayant des groupes sulfo liés à des atomes de carbone acycliques d'un squelette carboné acyclique saturé contenant des atomes d'azote, ne faisant pas partie de groupes nitro ou nitroso, liés au squelette carboné contenant des groupes amino liés au squelette carboné
A61K 31/138 - Aryloxyalkylamines, p. ex. propranolol, tamoxifène, phénoxybenzamine
25.
Formulation comprising glycopyrrolate, method and apparatus
A method is disclosed for making a pharmaceutical composition for pulmonary administration comprising co-jet milling glycopyrrolate and magnesium stearate, wherein the co-jet milled glycopyrrolate and magnesium stearate is then subjected to a conditioning step which includes exposure of the co-jet milled glycopyrrolate and magnesium stearate to humidity. A composition made by this method is also disclosed.
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 31/573 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne à deux atomes de carbone, p. ex. prégnane ou progestérone substitués en position 21, p. ex. cortisone, dexaméthasone, prednisone ou aldostérone
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
(1) Pharmaceutical preparations for the treatment of diseases and conditions of the respiratory system none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; pharmaceutical preparations for the treatment of diseases and conditions of the respiratory system, diseases and conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases and conditions of the gastro-intestinal system, diseases and conditions of the central nervous system, namely encephalitis, epilepsy, Alzheimer's, cerebral palsy, Parkinson's disease, Huntington's disease and multiple sclerosis, central nervous system infections, brain diseases, nervous system infections movement disorders, ocular motility disorders, spinal cord diseases, diseases and conditions of the endocrine system, namely growth and thyroid disorders, diseases and conditions of the genito-urinary system, namely, cancer, infertility, sexually transmitted diseases, incontinence, and sexual dysfunction, infectious diseases, namely respiratory infections, bacterial skin infections, fungal skin infections, viral skin infections and parasitic skin infections none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; pharmaceutical preparations for the alleviation and prevention of pain none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; inhalers filled with powders for the treatment of diseases and conditions of the respiratory system, diseases and conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases and conditions of the gastro-intestinal system, diseases and conditions of the central nervous system, namely encephalitis, epilepsy, Alzheimer's, cerebral palsy, Parkinson's disease, Huntington's disease and multiple sclerosis, central nervous system infections, brain diseases, nervous system infections movement disorders, ocular motility disorders, spinal cord diseases, diseases and conditions of the endocrine system, namely growth and thyroid disorders, diseases and conditions of the genito-urinary system, namely, cancer, infertility, sexually transmitted diseases, incontinence, and sexual dysfunction, infectious diseases, namely respiratory infections, bacterial skin infections, fungal skin infections, viral skin infections and parasitic skin infections none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; pharmaceutical preparations, namely, powders for asthma inhalers none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; pharmaceutical preparations, namely, powders for transdermal injection for the alleviation and prevention of pain, for the treatment of diseases and conditions of the respiratory system, diseases and conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases and conditions of the gastro-intestinal system, diseases and conditions of the central nervous system, namely encephalitis, epilepsy, Alzheimer's, cerebral palsy, Parkinson's disease, Huntington's disease and multiple sclerosis, central nervous system infections, brain diseases, nervous system infections movement disorders, ocular motility disorders, spinal cord diseases, diseases and conditions of the endocrine system, namely growth and thyroid disorders, diseases and conditions of the genito-urinary system, namely, cancer, infertility, sexually transmitted diseases, incontinence, and sexual dysfunction, infectious diseases, namely respiratory infections, bacterial skin infections, fungal skin infections, viral skin infections and parasitic skin infections none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; pharmaceutical preparations for oral ingestion for the treatment of diseases and conditions of the respiratory system, diseases and conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases and conditions of the gastro-intestinal system, diseases and conditions of the central nervous system, namely encephalitis, epilepsy, Alzheimer's, cerebral palsy, Parkinson's disease, Huntington's disease and multiple sclerosis, central nervous system infections, brain diseases, nervous system infections movement disorders, ocular motility disorders, spinal cord diseases, diseases and conditions of the endocrine system, namely growth and thyroid disorders, diseases and conditions of the genito-urinary system, namely, cancer, infertility, sexually transmitted diseases, incontinence, and sexual dysfunction, infectious diseases, namely respiratory infections, bacterial skin infections, fungal skin infections, viral skin infections and parasitic skin infections none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; pharmaceutical preparations for topical administration for the treatment of diseases and conditions of the respiratory system, diseases and conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases and conditions of the gastro-intestinal system, diseases and conditions of the central nervous system, namely encephalitis, epilepsy, Alzheimer's, cerebral palsy, Parkinson's disease, Huntington's disease and multiple sclerosis, central nervous system infections, brain diseases, nervous system infections movement disorders, ocular motility disorders, spinal cord diseases, diseases and conditions of the endocrine system, namely growth and thyroid disorders, diseases and conditions of the genito-urinary system, namely, cancer, infertility, sexually transmitted diseases, incontinence, and sexual dysfunction, infectious diseases, namely respiratory infections, bacterial skin infections, fungal skin infections, viral skin infections and parasitic skin infections none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; inhaled pharmaceutical preparations for the treatment of respiratory diseases and disorders none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; drug delivery agents in the form of powders that provide controlled release of the active ingredients for a wide variety of pharmaceuticals none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; medicaments for the treatment of erectile dysfunction none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; medicaments for the treatment of chronic obstructive pulmonary disease none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; medicaments for the treatment of premature ejaculation none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; medicaments for the treatment of cystic fibrosis none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; medicaments for the treatment of female sexual dysfunction none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; medicaments for the treatment of migraines none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions; medicaments for the treatment of asthma, none of the aforesaid wares are for use in the veterinary field or for use in association with autoimmune and inflammatory diseases and conditions.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Medical preparations; pharmaceutical preparations for
medical purposes; biological preparations for medical
purposes; pharmaceutical preparations formulated for
pulmonary delivery via inhalation; pharmaceutical
preparations for the prevention or treatment of diseases or
conditions of the respiratory and cardiovascular systems. Medical apparatus and instruments; inhalers; metered dose
inhalers; active dry powder inhalers; passive dry powder
inhalers; nebulisers for respiration therapy; respirators
for artificial respiration; parts and fittings for all the
aforesaid goods. Scientific research, development, design, analysis, testing
and investigation relating to medical preparations and drug
delivery devices; medical research; research relating to
drug delivery devices; research relating to drug
formulation; pharmaceutical development; preparation and
formulation of pharmaceuticals; device and product testing.
Systems and methods are disclosed for simultaneously jet milling and conditioning particulate material comprising a grinding chamber and an aerosol generator arranged to supply liquid aerosol into the grinding chamber. A composition made by this method is also disclosed.
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
B02C 19/06 - Appareils utilisant un courant de fluides
Systems and methods are disclosed for simultaneously jet milling and conditioning particulate material comprising a grinding chamber and an aerosol generator arranged to supply liquid aerosol into the grinding chamber. A composition made by this method is also disclosed.
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
B02C 19/06 - Appareils utilisant un courant de fluides
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Medical preparations; pharmaceutical preparations for
medical purposes; biological preparations for medical
purposes; pharmaceutical preparations formulated for
pulmonary delivery via inhalation; pharmaceutical
preparations for the prevention or treatment of diseases or
conditions of the respiratory and cardiovascular systems. Medical apparatus and instruments; drug delivery devices;
inhalers; metered dose inhalers; active dry powder inhalers;
passive dry powder inhalers; nebulisers for respiration
therapy; respirators for artificial respiration; parts and
fittings for all the aforesaid goods. Scientific research, development, design, analysis, testing
and investigation relating to medical preparations and drug
delivery devices; medical research; research relating to
drug delivery devices; research relating to drug
formulation; pharmaceutical development; preparation and
formulation of pharmaceuticals; device and product testing.
A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
32.
POLYMORPHIC FORMS OF (S)-3-(3(1-METHYL-2-OXO-5-(PYRAZOLO[1,5-A]PYRIDINE-3(2H)-YL)PIPERIDIN-1-YL)-3-OXOPROPANENITRILE
The invention relates to polymorphic forms of (S)-3-(3-(1-methyl-2-oxo-5-(pyrazolo[1,5-a]py yl)-1H-imidazo[4,5-b]pyridine-3(2H)-yl)piperidin-1-yl)-3-oxopropanenitrile and their use as therapeutic agents for the treatment of respiratory diseases.
A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine
C07D 519/00 - Composés hétérocycliques contenant plusieurs systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un système carbocyclique commun non prévus dans les groupes ou
The invention relates to polymorphic forms of (S)-3-(3-(1-methyl-2-oxo-5-(pyrazolo[1,5-a]py yl)-1H-imidazo[4,5-b]pyridine-3(2H)-yl)piperidin-1-yl)-3-oxopropanenitrile and their use as therapeutic agents for the treatment of respiratory diseases.
C07D 519/00 - Composés hétérocycliques contenant plusieurs systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un système carbocyclique commun non prévus dans les groupes ou
A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical substances and products for use in the manufacture of medical preparations. Medical preparations; pharmaceutical preparations for medical purposes; biological preparations for medical purposes; pharmaceutical preparations formulated for pulmonary delivery via inhalation; pharmaceutical preparations for the prevention or treatment of diseases or conditions of the respiratory and cardiovascular systems. Medical apparatus and instruments; drug delivery devices; inhalers; metered dose inhalers; active dry powder inhalers; passive dry powder inhalers; nebulisers for respiration therapy; respirators for artificial respiration; parts and fittings for all the aforesaid goods. Scientific research, development, design, analysis, testing and investigation relating to medical preparations and drug delivery devices; medical research; research relating to drug delivery devices; research relating to drug formulation; pharmaceutical development; preparation and formulation of pharmaceuticals; device and product testing.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical substances and products for use in the manufacture of medical preparations. Medical preparations; pharmaceutical preparations for medical purposes; biological preparations for medical purposes; pharmaceutical preparations formulated for pulmonary delivery via inhalation; pharmaceutical preparations for the prevention or treatment of diseases or conditions of the respiratory and cardiovascular systems. Medical apparatus and instruments; drug delivery devices; inhalers; metered dose inhalers; active dry powder inhalers; passive dry powder inhalers; nebulisers for respiration therapy; respirators for artificial respiration; parts and fittings for all the aforesaid goods. Scientific research, development, design, analysis, testing and investigation relating to medical preparations and drug delivery devices; medical research; research relating to drug delivery devices; research relating to drug formulation; pharmaceutical development; preparation and formulation of pharmaceuticals; device and product testing.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical substances and products for use in the manufacture of medical preparations. Medical preparations; pharmaceutical preparations for medical purposes; biological preparations for medical purposes; pharmaceutical preparations formulated for pulmonary delivery via inhalation; pharmaceutical preparations for the prevention or treatment of diseases or conditions of the respiratory and cardiovascular systems. Medical apparatus and instruments; drug delivery devices; inhalers; metered dose inhalers; active dry powder inhalers; passive dry powder inhalers; nebulisers for respiration therapy; respirators for artificial respiration; parts and fittings for all the aforesaid goods. Scientific research, development, design, analysis, testing and investigation relating to medical preparations and drug delivery devices; medical research; research relating to drug delivery devices; research relating to drug formulation; pharmaceutical development; preparation and formulation of pharmaceuticals; device and product testing.
37.
FORMULATION COMPRISING GLYCOPYRROLATE, METHOD AND APPARATUS
A method is disclosed for making a pharmaceutical composition for pulmonary administration comprising co-jet milling glycopyrrolate and magnesium stearate, wherein the co-jet milled glycopyrrolate and magnesium stearate is then subjected to a conditioning step which includes exposure of the co-jet milled glycopyrrolate and magnesium stearate to humidity. A composition made by this method is also disclosed.
A61J 3/02 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration la forme de poudres
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
38.
FORMULATION COMPRISING GLYCOPYRROLATE, METHOD AND APPARATUS
A method is disclosed for making a pharmaceutical composition for pulmonary administration comprising co-jet milling glycopyrrolate and magnesium stearate, wherein the co-jet milled glycopyrrolate and magnesium stearate is then subjected to a conditioning step which includes exposure of the co-jet milled glycopyrrolate and magnesium stearate to humidity. A composition made by this method is also disclosed.
The present invention concerns a method for making an inhaled pharmaceutical composition with improved powder handling properties comprising a stearate, a method of preparing such a composition, and the use of such a stearate in a composition when dispensed into a receptacle for use in a dry powder inhaler receptacle.
A method is disclosed for making a pharmaceutical composition for pulmonary administration comprising a pharmaceutically active protein or nucleic acid particle, the method comprising a step in which the inhalable pharmaceutically active protein or nucleic acid particle is acoustically blended in a resonant acoustic blender. The invention also relates to compositions for inhalation prepared by the method.
The present invention concerns a method for making an inhaled pharmaceutical composition with improved powder handling properties comprising a stearate, a method of preparing such a composition, and the use of such a stearate in a composition when dispensed into a receptacle for use in a dry powder inhaler receptacle.
The present invention concerns a method for making an inhaled pharmaceutical composition with improved powder handling properties comprising a stearate, a method of preparing such a composition, and the use of such a stearate in a composition when dispensed into a receptacle for use in a dry powder inhaler receptacle.
The invention discloses spray-dried compositions for inhalation and methods for preparing such powder compositions. The compositions of the invention are produced by spray-drying taurine under conditions that (i) retain the physical and chemical stability of the composition during spray drying and upon storage, (ii) protect the powder composition from aggregation and (iii) provide particles suitable for aerosolisation.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 47/20 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant du soufre, p. ex. sulfoxyde de diméthyle [DMSO], docusate, laurylsulfate de sodium ou acides aminosulfoniques
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
A61K 31/4045 - Indole-alkylaminesLeurs amides, p. ex. sérotonine, mélatonine
C07C 309/14 - Acides sulfoniques ayant des groupes sulfo liés à des atomes de carbone acycliques d'un squelette carboné acyclique saturé contenant des atomes d'azote, ne faisant pas partie de groupes nitro ou nitroso, liés au squelette carboné contenant des groupes amino liés au squelette carboné
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
N-containing heteroaryl derivatives of formula I or II, wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as JAK, particularly JAK3, kinase inhibitors.
A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
C07D 473/00 - Composés hétérocycliques contenant des systèmes cycliques purine
C07D 519/00 - Composés hétérocycliques contenant plusieurs systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un système carbocyclique commun non prévus dans les groupes ou
A method is disclosed for making a pharmaceutical composition for pulmonary administration, the method comprising a step in which an inhalable pharmaceutically active material is acoustically blended in a resonant acoustic blender. The invention also relates to compositions for inhalation prepared by the method.
N-containing heteroaryl derivatives of formula I or II, wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as JAK, particularly JAK3, kinase inhibitors.
A method of processing an active ingredient, the method comprising submitting a pharmaceutically active ingredient in the absence of excipients and/or additives to compression and shearing forces. The invention also relates to compositions comprising an active prepared by the method.
B02C 23/00 - Procédés auxiliaires, dispositifs auxiliaires ou accessoires spécialement adaptés au broyage ou à la désagrégation non prévus dans les groupes ou non adaptés spécialement aux appareillages couverts par un seul des groupes
According to the invention there is provided heparin for use in the treatment of COPD, wherein, after administration to a subject, the heparin reduces inflammation in the lungs of the subject.
According to the invention there is provided a method of treating and/or preventing the symptoms of Parkinson's disease comprising delivering apomorphine, optionally in combination with levodopa and/or a dopamine agonist that is not apomorphine, wherein apomorphine is administered by inhalation.
42 - Services scientifiques, technologiques et industriels, recherche et conception
45 - Services juridiques; services de sécurité; services personnels pour individus
Produits et services
(1) Inhalers for therapeutic use. (1) Scientific research, development, design, analysis, testing and investigation in the field of pharmaceutical preparations and drug delivery devices; medical research; research in the field of drug delivery devices; research in the field of drug formulation; pharmaceutical developments; preparation and formulation of pharmaceuticals; medical device testing services; exploitation of intellectual property, namely provision of licenses for pharmaceutical preparations, substances and products; provision of licences for medical apparatus and instruments; provision of licences for drug delivery devices; provision of licenses for pharmaceutical preparations for pulmonary delivery; provision of licences for intellectual property.
The present invention relates to suspension formulations, especially those for delivering a pharmaceutically active agent in aerosol form using a spray or aerosol device, such as a pressurized metered dose inhaler (pMDI). The formulations may be for pulmonary, nasal, buccal or topical administration, but are preferably for pulmonary inhalation.
A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
A61K 31/58 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes contenant des hétérocycles, p. ex. danazol, stanozolol, pancuronium ou digitogénine
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
53.
INGREDIENTS FOR INHALATION AND METHODS FOR MAKING THE SAME
A method of processing an active ingredient, the method comprising submitting a pharmaceutically active ingredient in the absence of excipients and/or additives to compression and shearing forces. The invention also relates to compositions comprising an active prepared by the method.
A method of processing an active ingredient, the method comprising submitting a pharmaceutically active ingredient in the absence of excipients and/or additives to compression and shearing forces. The invention also relates to compositions comprising an active prepared by the method.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical substances and products for use in the manufacture of medical preparations. Pharmaceutical and veterinary preparations, substances and products; chemical preparations and products for medical and veterinary purposes, all for administration to human or animal patients; pharmaceutical preparations for pulmonary delivery; inhalants; powders for inhalers; powders for asthma inhalers; powders for transdermal injection; pharmaceutical and veterinary preparations for oral ingestion; pharmaceutical and veterinary preparations for topical administration; all the above goods not for use in the dental field. Medical and veterinary apparatus, articles and aids, all for the administration of pharmaceutical preparations to human or animal patients; devices for the administration of pharmaceutical preparations; drug delivery devices; devices for metering and/or dispensing pharmaceutical preparations; inhalers; dry powder inhalers; inhalers for the treatment of asthma; nebulisers; parts and fittings for all the aforesaid goods; all the above goods not for use in the dental field. Scientific research, development, design, analysis, testing and investigation relating to pharmaceutical preparations and drug delivery devices; medical research; research relating to drug delivery devices; research relating to drug formulation; pharmaceutical development; preparation and formulation of pharmaceuticals; device and product testing; exploitation of intellectual property; provision of licences for pharmaceutical preparations, substances and products; provision of licences for medical and veterinary apparatus and instruments; provision of licences for drug delivery devices; provision of licenses for pharmaceutical preparations for pulmonary delivery; provision of licences for intellectual property.
The present invention relates to suspension formulations, especially those for delivering a pharmaceutically active agent in aerosol form using a spray or aerosol device, such as a pressurised metered dose inhaler (pMDI). The formulations may be for pulmonary, nasal, buccal or topical administration, but are preferably for pulmonary inhalation. The suspension fomulation comprises particles of active agent, a propellant one or more suspension stabiliser (amino acid, leucine, saccharide, disaccharide, trehalose) and/or a co-solvent (alcohol, ethanol).
The present invention relates to pharmaceutical compositions comprising triptans, such as sumatriptan, and their uses in therapy. In particular, the invention relates to compositions for administration via the inhaled route.
A61K 31/422 - Oxazoles non condensés et contenant d'autres hétérocycles
A61K 31/454 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pimozide, dompéridone
The present invention relates to improved treatment of diseases and disorders of the central nervous system by administration of apomorphine. In particular, the administration is via pulmonary inhalation. The invention provides the means for improving the treatment of a number of conditions, including Parkinson's Disease.
The present invention relates to inhaler devices and bespoke pharmaceutical dry powder composition to be dispensed using such inhaler devices for pulmonary administration. In particular, the present invention relates to the provision of passive inhaler devices and dry powder compositions which are specifically formulated and prepared to be efficiently dispensed by such devices to reproducibly achieve a high delivered dose of the pharmaceutically active agent.
The present invention relates to the treatment of dry powder formulations, doses of which are measured out and placed into receptacles such as blisters or capsules, to be dispensed by a dry powder inhaler device (DPI). In particular, the present invention relates to methods of agitating a dose of a dry powder formulation to ensure that any compacted powder is broken up. It is easier to extract a loose powder from a receptacle than it is to extract powder which is compacted and so ensuring that the powder in a receptacle is not compacted can, in turn, lead to improvements in the administration of the powder formulation to the lung of the patient.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
16 - Papier, carton et produits en ces matières
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Pharmaceutical and veterinary preparations; medicaments
formulated for pulmonary delivery; medicaments for
inhalation; medicaments for erectile dysfunction;
medicaments for chronic obstructive pulmonary disease;
medicaments for premature ejaculation; medicaments for
cystic fibrosis; medicaments for female sexual dysfunction;
medicaments for migraine; medicaments for asthma. Surgical, medical, dental and veterinary apparatus and
instruments, drug delivery devices; inhalers; active dry
powder inhalers; passive dry powder inhalers; nebulisers;
parts and fittings for all of the aforesaid goods. Paper, cardboard and goods made from these materials, not
included in other classes; printed matter; photographs;
stationery; instructional and teaching material (except
apparatus); plastic materials for packaging (not included in
other classes); all the aforesaid being goods relating to
pharmaceuticals or drug delivery devices. Scientific and technological services and research and
design relating thereto; industrial analysis and research
services; pharmaceutical development services; preparation
and/or formulation of pharmaceuticals; device and product
testing services.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Pharmaceutical and veterinary preparations; medicaments
formulated for pulmonary delivery; medicaments for
inhalation; medicaments for erectile dysfunction;
medicaments for chronic obstructive pulmonary disease;
medicaments for premature ejaculation; medicaments for
cystic fibrosis; medicaments for female sexual dysfunction;
medicaments for migraine; medicaments for asthma. Surgical, medical, dental and veterinary apparatus and
instruments, drug delivery devices; inhalers; active dry
powder inhalers; passive dry powder inhalers; nebulisers;
parts and fittings for all of the aforesaid goods, but not
including arthroscopic surgical instruments. Scientific and technological services and research and
design relating thereto; industrial analysis and research
services; pharmaceutical development services; preparation
and/or formulation of pharmaceuticals; device and product
testing services.
63.
Dry powder composition comprising co-jet milled particles for pulmonary inhalation
The present invention relates to particles and to methods of making particles. In particular, the invention relates to methods of making composite active particles comprising a pharmaceutically active material for pulmonary inhalation, the method comprising a jet milling process.
The present invention is concerned with a refinement of the processing of particles that are to form a dry powder formulation which is to be administered to the lung using a dry powder inhaler (DPI) device. In particular, the present invention provides the processing of particles of active material and particles of carrier material in the presence of additive material to provide a powder composition which exhibits excellent powder properties and which is economical to produce.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
16 - Papier, carton et produits en ces matières
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemicals for use in science and industry; chemical substances and products for use in the manufacture of medical preparations; chemicals for use in the manufacture of powders for medicinal use. Pharmaceutical and veterinary preparations; pharmaceutical and veterinary preparations for the treatment of diseases or conditions of the respiratory system; pharmaceutical and veterinary preparations for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical and veterinary preparations for the alleviation or prevention of pain or inflammation; inhalers filled with powders for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; powders for asthma inhalers; powders for transdermal injection for the alleviation or prevention of pain, for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical and veterinary preparations for oral ingestion for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical and veterinary preparations for topical administration for the treatment of diseases or conditions of the respiratory system, diseases or conditions of the cardiovascular system, diabetes, cancer, arthritis, diseases or conditions of the gastro-intestinal system, diseases or conditions of the central nervous system, diseases or conditions of the endocrine system, diseases or conditions of the genito-urinary system, infections, skin disorders and gynecological conditions; pharmaceutical and veterinary preparations for erectile dysfunction; pharmaceutical and veterinary preparations for chronic obstructive pulmonary disease; pharmaceutical and veterinary preparations for premature ejaculation; pharmaceutical and veterinary preparations for cystic fibrosis; pharmaceutical and veterinary preparations for female sexual dysfunction; medicaments for migraine; pharmaceutical and veterinary preparations for asthma. Printed matter; leaflets, brochures, labels, booklets, manuals, magazines, books, guides, pamphlets, catalogues, journals, newsletters, press releases, dossiers being collections of scientific papers, patient record cards, prescription pads, posters; packaging for pharmaceuticals and medical devices; instructional and teaching material, worksheets, work books, notes and note books, slides and images, pre-recorded CD-ROMs. Scientific and technological services and research and design relating thereto; industrial analysis and research services; medical and veterinary device development services; pharmaceutical development services; pharmaceutical delivery system development services; preparation and/or formulation of pharmaceuticals; medical and veterinary device and product testing services.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
16 - Papier, carton et produits en ces matières
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Pharmaceutical and veterinary preparations; medicaments formulated for pulmonary delivery; medicaments for inhalation; medicaments for erectile dysfunction; medicaments for chronic obstructive pulmonary disease; medicaments for premature ejaculation; medicaments for cystic fibrosis; medicaments for female sexual dysfunction; medicaments for migraine; medicaments for asthma. Surgical, medical, dental and veterinary apparatus and instruments, drug delivery devices; inhalers; active dry powder inhalers; passive dry powder inhalers; nebulisers; parts and fittings for all of the aforesaid goods. Paper, cardboard and goods made from these materials, not included in other classes; printed matter; photographs; stationery; instructional and teaching material (except apparatus); plastic materials for packaging (not included in other classes); all the aforesaid being goods relating to pharmaceuticals or drug delivery devices. Education; providing of training; all the aforesaid being services relating to pharmaceuticals or drug delivery devices. Scientific and technological services and research and design relating thereto; industrial analysis and research services; pharmaceutical development services; preparation and/or formulation of pharmaceuticals; device and product testing services.
The present invention relates to pharmaceutical compositions comprising the antimuscarinic agent glycopyrrolate, for example the salt glycopyrronium bromide. In particular, the present invention relates to dry powder compositions which exhibit improved stability over time, and methods for producing the same.
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Scientific and technological services and research and design relating thereto; industrial analysis and research services; all the aforesaid being services relating to pharmaceuticals or drug delivery devices; pharmaceutical development services; preparations and/or formulation of pharmaceuticals; medical device and medical product testing services; pharmaceutical product development.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical substances and products for use in the manufacture of medical preparations. Pharmaceutical and veterinary preparations, substances and products; chemical preparations and products for medical and veterinary purposes; all for administration to human or animal patients; inhalants; powders for inhalers; powders for asthma inhalers; powders for transdermal injection; pharmaceutical and veterinary preparations for oral ingestion; pharmaceutical and veterinary preparations for topical administration; all the above goods not for use in the dental field. Medical and veterinary apparatus, articles and aids and parts and fittings therefor; all for the administration of pharmaceutical preparations to human or animal patients; devices for the administration of pharmaceutical preparations; devices for metering and/or dispensing pharmaceutical preparations, inhalers and parts and fittings therefor; inhalers for the treatment of asthma and parts and fittings therefor; aerosol dispensers; all the above goods not for use in the dental field. Scientific research, development, design, testing and investigation relating to pharmaceutical preparations; medical research; research relating to drug delivery devices; research relating to drug formulation.
