A radio frequency system for a radiation therapy machine includes a first portion containing a first gas at a first pressure, a second portion containing a second gas at a second pressure, the second gas being different from the first gas, and a component between the first portion and the second portion, the component containing the first gas at the first pressure.
In some embodiments, a method of screening drug-radiation interactions includes determining a drug panel having a plurality of drugs to analyze; obtaining a cell line panel having one or more molecular parameters of interest and a plurality of cell lines; obtaining a cell line density and intrinsic radiotherapy response for each cell line in the cell line panel; determining a subset of drugs of the drug panel; determining initial radiation-dose-drug-concentration (RDDC) combinations for use with the subset of drugs of the drug panel; determining full concentration-response relationships for the cell lines of the cell line panel using the initial RDDC combinations; determining an RDDC combination subset from the initial RDDC combinations based on the full concentration-response relationships; and screening the cell lines of the cell line panel using the RDDC combination subset for each drug within the drug panel. Numerous other embodiments are provided.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 1/32 - Inoculateur ou échantillonneur du type à champs multiples ou en continu
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
A radiation support system for radiation therapy includes a waveguide assembly. The waveguide assembly includes a waveguide (4400) extending along a first axis, a mode launcher (4402) extending along a second axis, the second axis being different than the first axis, and a resonant cavity twist (4401) coupling the waveguide to the mode launcher.
H01P 1/16 - Sélecteurs de mode, p. ex. pour empêcher ou favoriser la propagation suivant un mode donnéConvertisseurs de mode
H01P 1/17 - Dispositifs auxiliaires pour faire tourner le plan de polarisation pour produire une rotation continue du plan de polarisation, p. ex. une polarisation circulaire
H05H 7/22 - Détails d'accélérateurs linéaires, p. ex. tubes de glissement
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
H01P 5/08 - Dispositifs de couplage du type guide d'ondes destinés au couplage de lignes ou de dispositifs de différentes sortes
A radiation support system for radiation therapy includes a waveguide assembly. The waveguide assembly includes a waveguide extending along a first axis, a mode launcher extending along a second axis, the second axis being different than the first axis, and a resonant cavity twist coupling the waveguide to the mode launcher.
H01J 25/58 - Magnétrons, c.-à-d. tubes comprenant un système magnétique produisant un champ H qui croise le champ E dont l'espace électronique présente une forme propre à permettre aux électrons de se mouvoir entièrement autour de la cathode ou de l'électrode de guidage comprenant un certain nombre de résonateursMagnétrons, c.-à-d. tubes comprenant un système magnétique produisant un champ H qui croise le champ E dont l'espace électronique présente une forme propre à permettre aux électrons de se mouvoir entièrement autour de la cathode ou de l'électrode de guidage comprenant un résonateur complexe, p. ex. une hélice
H01J 23/20 - Cavités résonnantesRéglage ou accord de celles-ci
H01J 23/48 - Couplage du circuit d'interaction avec des lignes coaxialesDispositifs du type à hélices couplées
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Downloadable and recorded computer software for database
management, managing patient medical information,
application and database integration, creation of firewalls,
virtualization, and data backup, recovery and archiving;
downloadable and recorded computer software that enables
cloud computing, provides access to cloud-based scalable
computing resources and data storage, and monitors cloud and
application performance; downloadable and recorded computer
application software for database management in virtual
environments; downloadable and recorded cloud-computing
software for deploying virtual machines to a cloud computing
platform and managing virtual machines on a cloud computing
platform; downloadable computer software platforms for cloud
computing networks and applications. Platform as a service (PaaS) featuring computer software
platforms for use in database management in the medical
field; design and development of computer software for
database management and cloud storage of data in the medical
field; software as a service (SaaS) services in the nature
of hosting cloud-based software of others; cloud computing
featuring software for use in database management, in the
medical field; computer services, namely, data recovery
services, data backup services, data restoration services,
being computer data recovery, providing virtual and
non-virtual application servers, web servers, file servers,
co-location servers, load balancing servers, redundancy
servers, media servers and database servers of variable
capacity to third party computing and data storage
facilities; computer disaster recovery planning;
cybersecurity services in the nature of restricting
unauthorized access to computer systems; technical support
services namely, troubleshooting in the nature of diagnosing
computer hardware and software problems; provision of
virtual computer systems and virtual computer environments
through cloud computing; hosting the software, websites and
other computer applications of others on a virtual private
server; application service provider (ASP), namely, hosting
computer software applications of others; infrastructure as
a service (IaaS) services, namely, hosting servers for use
by others, hosting software for operating virtual servers
for use by others; cloud hosting of electronic databases and
virtual computing environments; administration of online
database systems and virtual computer environments for
others, being installation and configuration of server
software, creation and modification of structures of online
database systems and virtual computer environments,
performance monitoring and optimization, managing user
access; maintenance of online databases and virtual computer
environments for others, being data backup and conversion
services, data encryption services, data security services;
software as a service (SaaS) service featuring software for
database management, controlling and managing patient
medical information, deploying and managing virtual machines
to a cloud computing platform creation of firewalls, cloud
computing, providing access to cloud-based scalable
computing resources and data storage, monitoring cloud and
application performance, and data backup, recovery and
archiving.
6.
RADIOPAQUE GLASS RADIOEMBOLIZATION MICROPARTICLES AND RELATED METHODS
A method of performing a radioembolization treatment includes injecting 402 a plurality of radioembolization particles into a bloodstream of a patient to treat a target tissue. Each radioembolization particle of the plurality of radioembolization particles includes a radioactive core and a radiopaque layer. The method also includes obtaining 404 an image of the target tissue and the radioembolization particles to determine 406 a dose of radioactivity delivered to the target tissue by the plurality of radioembolization particles. wherein the image is one of a computerized tomography (CT) image and an x-ray image.
A61L 24/00 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie
A61K 51/12 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo caractérisées par un aspect physique particulier, p. ex. émulsion, microcapsules, liposomes
A61L 24/02 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie contenant des matériaux inorganiques
7.
MICROBEAD SIZE-DRIVEN ADAPTIVE VESSEL VISUALIZATION FOR PLANNING EMBOLIZATION PROCEDURES
A method of planning an embolization procedure for a patient includes capturing a 3D digital image of a vessel at a target site after a contrast agent has been administered to the vessel; determining diameters of the vessel based on the digital image; and outputting a digital representation of the vessel where different colors indicate different diameters of the vessel.
A61B 34/00 - Chirurgie assistée par ordinateurManipulateurs ou robots spécialement adaptés à l’utilisation en chirurgie
A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
8.
TEMPERATURE VOLUME HISTOGRAM GENERATION APPARATUS AND METHOD
To facilitate administering thermal ablation (such as, but not limited to, cryotherapy) to a patient's target volume, a control circuit can access characterizing information for a particular thermal ablation apparatus and then generate a temperature volume histogram as a function of the characterizing information for that particular thermal ablation apparatus.
A61B 34/00 - Chirurgie assistée par ordinateurManipulateurs ou robots spécialement adaptés à l’utilisation en chirurgie
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
9.
SELECTIVE INTERNAL RADIATION THERAPY MAPPING VIA MICROBEADS WITH DIFFERENT CONTRAST MATERIALS
A method includes determining a shunt fraction of microbeads by comparing a known ratio of a mixture of smaller microbeads loaded with a first contrast agent to larger microbeads loaded with a second contrast agent changes to a diffused ratio of the smaller microbeads to the larger microbeads after the mixture has been administered to a treatment site.
A61B 6/12 - Agencements pour détecter ou localiser des corps étrangers
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A61B 6/42 - Agencements pour détecter des radiations spécialement adaptés au diagnostic par radiations
A61B 6/50 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des parties du corps spécifiquesAppareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des applications cliniques spécifiques
A61K 49/04 - Préparations de contraste pour rayons X
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
10.
UPDATING RADIOTHERAPY TREATMENT PLANS USING INFORMATION DERIVED FROM WHOLE SLIDE IMAGES (WSIS)
Systems (600) and methods (S100) for adapting treatment plans to the characteristics of individual anatomical pathologies (e.g., tumors), and systems, methods, and devices for implementing an adaptive therapy workflow (220) that automatically updates (S103) treatment plans based on whole slide images (WSIs) of the target anatomical pathologies.
Systems and methods for adapting treatment plans to the characteristics of individual anatomical pathologies (e.g., tumors), and systems, methods, and devices for implementing an adaptive therapy workflow that automatically updates treatment plans based on whole slide images (WSIs) of the target anatomical pathologies.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Downloadable and recorded computer software for database management, managing patient medical information, application and database integration, creation of firewalls, virtualization, and data backup, recovery and archiving; downloadable and recorded computer software that enables cloud computing, provides access to cloud-based scalable computing resources and data storage, and monitors cloud and application performance; downloadable and recorded computer application software for database management in virtual environments; downloadable and recorded cloud-computing software for deploying virtual machines to a cloud computing platform and managing virtual machines on a cloud computing platform; downloadable computer software platforms for cloud computing networks and applications. (1) Platform as a service (PaaS) featuring computer software platforms for use in database management in the medical field; design and development of computer software for database management and cloud storage of data in the medical field; software as a service (SaaS) services in the nature of hosting cloud-based software of others; cloud computing featuring software for use in database management, in the medical field; computer services, namely, data recovery services, data backup services, data restoration services, being computer data recovery, providing virtual and non-virtual application servers, web servers, file servers, co-location servers, load balancing servers, redundancy servers, media servers and database servers of variable capacity to third party computing and data storage facilities; computer disaster recovery planning; cybersecurity services in the nature of restricting unauthorized access to computer systems; technical support services namely, troubleshooting in the nature of diagnosing computer hardware and software problems; provision of virtual computer systems and virtual computer environments through cloud computing; hosting the software, websites and other computer applications of others on a virtual private server; application service provider (ASP), namely, hosting computer software applications of others; infrastructure as a service (IaaS) services, namely, hosting servers for use by others, hosting software for operating virtual servers for use by others; cloud hosting of electronic databases and virtual computing environments; administration of online database systems and virtual computer environments for others, being installation and configuration of server software, creation and modification of structures of online database systems and virtual computer environments, performance monitoring and optimization, managing user access; maintenance of online databases and virtual computer environments for others, being data backup and conversion services, data encryption services, data security services; software as a service (SaaS) service featuring software for database management, controlling and managing patient medical information, deploying and managing virtual machines to a cloud computing platform creation of firewalls, cloud computing, providing access to cloud-based scalable computing resources and data storage, monitoring cloud and application performance, and data backup, recovery and archiving.
13.
VESSEL CONTRAST BASED INFERENCE OF SELECTIVE INTERNAL RADIATION THERAPY DOSIMETRY
A method includes recording (S2) 3D data of an organ of interest after administering microbeads into a patient to flow to the organ; segmenting (S3) arterial vascular structures with visible accumulations of the microbeads around the organ; determining (S4) diameters or lumens(s) of the arterial vascular structures; determining or estimating (S5) a degree of a filling factor in the arterial vascular structures; generating (S6) a microbead density map along the arterial vascular structures; extrapolating (S7) the microbead accumulation in parenchyma and/or tumor tissue in the organ; and generating (S8) a composite distribution map of the microbeads, the composite map including the arterial vascular structures with visible accumulations of the microbeads and the extrapolated microbead accumulation in the parenchyma and/or tumor tissue in the organ.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A61B 6/40 - Agencements pour générer des radiations spécialement adaptés au diagnostic par radiations
A61B 6/50 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des parties du corps spécifiquesAppareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des applications cliniques spécifiques
14.
DEVICE AND METHOD TO INTRAOPERATIVELY MEASURE RADIOACTIVITY OF RADIOEMBOLIZATION AGENT
A device to measure radioactivity of a radioembolization material including a container 110 to receive the radioem- bolization material; and a dosimeter 140 that measures the radioactivity of the radioembolization material in the container while the radioembolization material is being administered to a patient.
A61K 51/12 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo caractérisées par un aspect physique particulier, p. ex. émulsion, microcapsules, liposomes
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
G01T 1/00 - Mesure des rayons X, des rayons gamma, des radiations corpusculaires ou des radiations cosmiques
15.
APPARATUSES AND METHODS FOR TARGETED VAPORIZATION OF CRYOGEN
A cryoablation apparatus includes a Dewar configured to retain a volume of cryogen and a heater assembly positioned in the Dewar. The heater assembly includes at least one heater configured to heat a targeted portion of the cryogen as the volume of cryogen in the Dewar changes. The targeted portion of the cryogen is located at or near a top surface of a liquid level of the liquid cryogen.
F17C 7/04 - Vidage des gaz liquéfiés avec changement d'état, p. ex. vaporisation
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
F17C 3/08 - Récipients non sous pression assurant une isolation thermique par des espaces où le vide a été fait, p. ex. vases de Dewar
16.
COOLANT STATUS MONITORING FOR MICROWAVE ABLATION PROBE
A microwave ablation probe system includes a coolant delivery system to deliver coolant to a microwave ablation probe; a microwave generator to deliver microwave energy to the microwave ablation probe; and a computing system in communication with a thermal sensor on the microwave ablation probe to collect temperature data over time from the thermal sensor, wherein the computing system is configured to calculate the measured temperatures by the thermal sensor over time to determine if the coolant delivery system is cooling the microwave ablation probe, and provide feedback on ablation procedure progress.
G01K 3/10 - Thermomètres donnant une indication autre que la valeur instantanée de la température fournissant des différences de valeursThermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs différenciées par rapport au temps, p. ex. réagissant uniquement à une variation rapide de température
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
G01K 1/02 - Moyens d’indication ou d’enregistrement spécialement adaptés aux thermomètres
Three-dimensional models of radiotherapy equipment for
teaching purposes; three-dimensional models of radiotherapy
equipment for demonstration purposes. Three-dimensional models of radiotherapy equipment for
playing purposes.
A control circuit can access multi-dimensional information for a particular patient and then automatically determine a supplemental boundary for at least one portion of the particular patient (such as a treatment target comprising a part of the patient's heart and/or one or more organs-at-risk) as a function, at least in part, of the multi-dimensional information. The latter may comprise determining a margin that is added to a boundary of the at least one portion of the particular patient. The control circuit can then, for example, determine a planning treatment volume as a function, at least in part, of that supplemental boundary. These teachings will then permit, for example, optimizing a cardiac radioablation treatment plan for the particular patient as a function of various dimensions of movement as derived, at least in part, from the aforementioned multi-dimensional information.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
19.
MOTION COMPENSATION IN CARDIAC RADIOABLATION TREATMENT PLANNING
A control circuit can access (401) multi-dimensional information for a particular patient and then automatically determine (406) a supplemental boundary for at least one portion of the particular patient (such as a treatment target comprising a part of the patient's heart and/or one or more organs-at-risk) as a function, at least in part, of the multi-dimensional information. The latter may comprise determining a margin that is added to a boundary of the at least one portion of the particular patient. The control circuit can then, for example, determine (407) a planning treatment volume as a function, at least in part, of that supplemental boundary. These teachings will then permit, for example, optimizing (408) a cardiac radioablation treatment plan for the particular patient as a function of various dimensions of movement as derived, at least in part, from the aforementioned multidimensional information.
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A control circuit can access multi-dimensional information for a particular patient and then automatically determine a supplemental boundary for at least one portion of the particular patient (such as a treatment target and/or one or more organs-at-risk) as a function, at least in part, of the multi-dimensional information. The latter may comprise determining a margin that is added to a boundary of the at least one portion of the particular patient. The control circuit can then, for example, determine a planning treatment volume as a function, at least in part, of that supplemental boundary. These teachings will then permit, for example, optimizing a radiation-based therapeutic treatment plan for the particular patient as a function of various dimensions of movement as derived, at least in part, from the aforementioned multi-dimensional information.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
A control circuit can access 400 multi-dimensional information for a particular patient and then automatically determine 406 a supplemental boundary for at least one portion of the particular patient (such as a treatment target and/or one or more organs-at-risk) as a function, at least in part, of the multi-dimensional information. The latter may comprise determining a margin that is added to a boundary of the at least one portion of the particular patient. The control circuit can then, for example, determine 407 a planning treatment volume as a function, at least in part, of that supplemental boundary. These teachings will then permit, for example, optimizing 408 a radiation-based therapeutic treatment plan for the particular patient as a function of various dimensions of movement as derived, at least in part, from the aforementioned multi-dimensional information.
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
A radiation system includes an X-ray target configured to convert an electron beam into an X-ray beam. The X-ray target includes a plurality of target layers and each of the plurality of target layers are configured to convert a portion of the electron beam into a portion of the X-ray beam.
A microwave ablation apparatus includes a movable cart with a support surface and a portable base unit including at least one microwave generator and at least one coolant flow generator. The portable base unit is removably positioned on the support surface. The at least one ablation probe assembly is configured to couple to the at least one microwave generator and the at least one coolant flow generator.
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
An example computer-implemented method for a treatment delivery system is disclosed. The method includes receiving an input requesting movement of a couch of the treatment delivery system from a first position to a second position, and in response to the input, transmitting, to a surface guidance system, position information for the couch, wherein the position information is for modifying a reference patient surface, and causing the couch to move from the first position to the second position.
An example computer-implemented method for a treatment delivery system is disclosed. The method includes transmitting, to a surface guidance system, a first signal indicating that delivery of radiation is beginning to a region of patient anatomy, wherein the radiation includes a first portion and a second portion. After delivering the first portion to the region, the method also includes receiving a second signal from the surface guidance system, wherein the interrupt signal is based on a reference surface generated in response to the first signal, and in response to the second signal, halting delivery to the region of the second portion of the radiation.
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). A method comprises presenting a plurality of pages for display, each corresponding to a stage of a radiotherapy treatment for a patient; in response to receiving an indication that a surface of a patient is aligned, retrieving, from a radiotherapy file, a first image of an internal target aligned in accordance with treatment attributes; receiving a second image of the internal target; overlaying on a first page of the plurality of pages, the first image and the second image, the first page displaying a direction to position the internal target in the second image to align with the internal target in the first image; and when the internal target is aligned, presenting for display a second page of the plurality of pages corresponding to a subsequent stage of the radiotherapy treatment for the patient.
A microwave ablation apparatus includes a base unit with at least one microwave generator and at least one coolant flow generator and an operating platform coupled to a processor and memory. The operating platform is configured to receive ablation zone inputs corresponding to desired characteristics of an ablation zone and operate the at least one microwave generator to form the ablation zone with the desired characteristics.
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
28.
PUMP AND CASSETTE SYSTEM FOR USE IN MICROWAVE ABLATION
An apparatus for cooling an ablation probe includes a cassette receptacle configured to accept a cassette including a supply tube for supplying a coolant to the ablation probe. The apparatus also includes a pump head movably positioned proximate the cassette receptacle. The pump head is configured to move between a loading position and an operating position. The pump head includes one or more rollers configured to engage the supply tube of the cassette when the pump head is in the operating position. The apparatus also includes an actuator coupled to the pump head. The actuator is configured to move the pump head between the loading position and the operating position.
F04B 43/12 - "Machines", pompes ou installations de pompage ayant des organes de travail flexibles à action péristaltique
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
An apparatus for generating a microwave signal including a housing with a plurality of walls defining an interior volume, an inlet opening and an outlet opening. The apparatus also includes a power supply positioned in the interior volume and a first microwave generator and a second microwave generator each operably coupled to the power supply, and each positioned in the interior volume spaced apart from the power supply. The apparatus also includes a heat sink positioned in the interior volume that contacts the power supply, the first microwave generator and the second microwave generator. The apparatus also includes a fan positioned in the interior volume at a first end of the heat sink. The fan is configured to draw an airflow into the interior volume from the inlet opening and move the airflow through the heat sink.
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
30.
MICROWAVE ABLATION PROBE ASSEMBLY AND CABLE STRUCTURE
A cable bundle for a microwave ablation probe assembly may include a cable configured to deliver a microwave signal from a microwave generator to an antenna in a probe and a coolant conduit positioned adjacent the cable. The cable bundle may also include a conductive layer positioned externally to the cable and the coolant conduit.
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
(1) Three-dimensional models of radiotherapy equipment for teaching purposes; three-dimensional models of radiotherapy equipment for demonstration purposes.
(2) Three-dimensional models of radiotherapy equipment for playing purposes.
32.
APPARATUSES AND METHODS FOR CRYOGEN MEASUREMENT AND CONTROL FOR CRYOABLATION SYSTEMS
A cryoablation apparatus includes a Dewar defining an interior volume configured to retain a volume of cryogen, a supply tube extending into the interior volume of the Dewar, a heating assembly positioned at a distal end of the supply tube, a pump assembly positioned proximate the heating assembly, and a lid assembly coupled to the Dewar at the proximate end of the supply tube opposite to the distal end of the supply tube. The cryoablation apparatus also includes a capacitance-based cryogen liquid level sensor positioned in the Dewar.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A cryoablation apparatus includes a Dewar, a cryogen flow path fluidly coupled to the Dewar to supply cryogen to a cryoprobe, a first pressure sensor and a second pressure sensor positioned at a first portion of the cryogen flow path and at a second portion of the cryogen flow path, respectively, a first valve and a second valve each positioned along the cryogen flow path and each configured to operate in an open position and in a closed position, and a diagnostics control operatively coupled to the first pressure sensor, the second pressure sensor, the first valve, and the second valve. The diagnostics control is configured to determine whether a blockage or leak exists in the first portion and the second portion of the cryogen flow path. The apparatus also includes a gas assembly configured to supply a cryogen gas to purge the flow path.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
34.
Radiation therapy treatment planning and radiation therapy treatment including mu distribution visualization
A system includes at least one processor configured to execute computer executable instructions to cause the system to: generate or obtain a first radiation treatment plan for a treatment target in a patient, the first radiation treatment plan prescribing beam characteristics for a plurality of beamlets or spots in the treatment target, the beam characteristics including a monitor unit value associated with each of the plurality of beamlets or spots in at least a first field; and display, via a graphical user interface, at least one representation of a first distribution of monitor units for the first radiation treatment plan, the at least one representation of the first distribution of monitor units indicating, for each respective monitor unit value, a number of beamlets or spots in at least the first field having the respective monitor unit value.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Downloadable and recorded computer software for database management, managing patient medical information, application and database integration, creation of firewalls, virtualization, and data backup, recovery and archiving. Downloadable and recorded computer software that enables cloud computing, provides access to cloud-based scalable computing resources and data storage, and monitors cloud and application performance; Downloadable and recorded computer application software for database management in virtual environments; Downloadable and recorded cloud-computing software for deploying virtual machines to a cloud computing platform and managing virtual machines on a cloud computing platform; Downloadable computer software platforms for cloud computing networks and applications. Platform as a service (PAAS) featuring computer software platforms for use in database management in the medical field; Design and development of computer software for database management and cloud storage of data in the medical field; Software as a service (SAAS) services in the nature of hosting cloud-based software of others; Cloud computing featuring software for use in database management, in the medical field; Computer services, namely, data recovery services, data backup services, data restoration services, being computer data recovery, providing virtual and non-virtual application servers, web servers, file servers, co-location servers, load balancing servers, redundancy servers, media servers and database servers of variable capacity to third party computing and data storage facilities; Computer disaster recovery planning; Cybersecurity services in the nature of restricting unauthorized access to computer systems; Technical support services namely, troubleshooting in the nature of diagnosing computer hardware and software problems; Provision of virtual computer systems and virtual computer environments through cloud computing; Hosting the software, websites and other computer applications of others on a virtual private server; Application service provider (ASP), namely, hosting computer software applications of others; Infrastructure as a service (IAAS) services, namely, hosting servers for use by others, hosting software for operating virtual servers for use by others; Cloud hosting of electronic databases and virtual computing environments; Administering and maintaining online databases and virtual computing environments for others; Software as a service (SaaS) service featuring software for database management, controlling and managing patient medical information, deploying and managing virtual machines to a cloud computing platform creation of firewalls, cloud computing, providing access to cloud-based scalable computing resources and data storage, monitoring cloud and application performance, and data backup, recovery and archiving.
Disclosed herein are methods and systems for training artificial intelligence (AI) models. A central server may train an AI model by outputting, onto an electronic device operated by a user, results of execution of the AI model; monitoring the electronic device to identify a set of interactions between the user and the electronic device while the electronic device is outputting the results; generating a first training dataset corresponding to the user's interactions with the electronic device, the first training dataset corresponding to a frequency of correction of results; generating a second training dataset corresponding to the user's input to a prompt requesting the user to input a numerical value associated with an accuracy of the results; and training the AI model using the first and second training datasets.
G06F 18/214 - Génération de motifs d'entraînementProcédés de Bootstrapping, p. ex. ”bagging” ou ”boosting”
G06F 8/71 - Gestion de versions Gestion de configuration
G06F 18/21 - Conception ou mise en place de systèmes ou de techniquesExtraction de caractéristiques dans l'espace des caractéristiquesSéparation aveugle de sources
G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
38.
PATIENT MARKING AND POSITIONING IN A RADIATION THERAPY SYSTEM
An example method for a radiation therapy system that includes a movable couch to perform radiation therapy has been disclosed. One method includes based on the X-ray images of an anatomical region of the patient that includes a target volume, reconstructing a digital volume of the anatomical region and based on a user input indicating a location of a patient origin in the digital volume, determining one or more shift values for repositioning the patient origin at an isocenter of the radiation therapy system with respect to a coordinate system. The method also includes obtaining a treatment plan that is based on the location of the patient origin and is associated with the target volume, based on the treatment plan, repositioning the movable couch so that the patient origin is disposed at the isocenter, and while the patient origin is disposed at the isocenter, directing a treatment beam to the patient origin in accordance with the treatment plan associated with the target volume.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A61B 6/10 - Moyens de sécurité spécialement adaptés à cet effet
A61B 6/46 - Agencements pour l’interface avec l’opérateur ou avec le patient
A method includes obtaining image data of the heart of the patient, obtaining image data of a torso of the patient, obtaining positions of electrodes at the torso, obtaining a measured ECG signal measured at the patient using the electrodes, parameterizing of a model for estimating electrical potentials on the skin of the torso of the patient depending on cardiac activity, determining multiple simulated ECG signals for multiple activation patterns using the model, and determining the cardiac activation area of the heart based on comparing the multiple simulated ECG signals with the measured ECG signal.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/318 - Modalités électriques se rapportant au cœur, p. ex. électrocardiographie [ECG]
A61B 5/349 - Détection de paramètres spécifiques du cycle de l'électrocardiogramme
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
41.
METHODS AND APPARATUS FOR RADIOABLATION TREATMENT AREA TARGETING AND GUIDANCE
Systems and methods for target area recommendation and guidance during radioablation treatment planning are disclosed. In some examples, a computing device receives (702) image data from one or more modalities for a patient. The computing device determines (708) a recommended target area for treatment based on the image data, and determines one or more corresponding segments of a segment model based on the recommended target area. Further, the computing device displays the segment model identifying the determined one or more segments, and receives (710) input data modifying the determined one or more segments. Based on the input data, the computing device updates (716) the one or more segments, and generates target definition data characterizing the updated one or more segments. The computing device transmits the target definition data for treating the patient.
Systems (100) and methods (700, 800, 900) for target area recommendation and guidance during radioablation treatment planning are disclosed. In some examples. a computing device (104) receives image data (103) from one or more modalities for a patient. The computing device (104) determines a recommended target area for treatment based on the image data (103), and determines one or more corresponding segments of a segment model based on the recommended target area. Further, the computing device (104) displays the segment model identifying the determined one or more segments. and receives input data modifying the determined one or more segments. Based on the input data, the computing device (104) updates the one or more segments, and generates target definition data characterizing the updated one or more segments. The computing device (104) transmits the target definition data for treating the patient.
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
43.
Display screen with graphical user interface for radiotherapy machine
Systems, devices and methods for internal dose adapted automated external radiation beam therapy, and systems and methods for an automated adaptive workflow to automatically generate a radiation treatment plan based on the internal dose and adapt the treatment plan to a current treatment session using a set of directives.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
Three-dimensional toy models of radiotherapy equipment for playing purposes Three-dimensional models of radiotherapy equipment for educational teaching purposes; Three-dimensional models of radiotherapy equipment for educational demonstration purposes
46.
MICROWAVE NETWORKS, WAVEGUIDES, MIXING CARTS, METHODS OF SUPPLYING GAS, AND GAS MANAGEMENT SYSTEMS FOR RADIATION THERAPY MACHINES
A microwave network for a radiation therapy machine having a microwave source and a linear accelerator, includes a waveguide configured to connect between the microwave source and the linear accelerator. The waveguide contains at least one of a first gas or a second gas, the first gas being 2,3,3,3-tetrafluoro-2-(trifluoromethyl) propanenitrile and the second gas being 1,1,1,3,4,4,4-heptafluoro-3-(trifluoromethyl)-2-butanone.
B01F 35/221 - Commande ou régulation des paramètres de fonctionnement, p. ex. du niveau de matière dans le mélangeur, de la température ou de la pression
A combination ablation probe includes a shell configured to be positioned at a target tissue in a patient and a conduit positioned inside the shell. The conduit is configured to supply a cryo-fluid toward a tip of the probe. The probe also includes a heater positioned radially outward of the conduit in the shell and at least one heat transfer element in thermal communication with the heater and the shell.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
48.
COMBINATION PROBE FOR CRYOABLATION AND THERMAL ABLATION WITH EXTERNAL HEATER
An ablation probe includes a shell configured to be positioned at a target tissue in a patient and a conduit positioned inside the shell. The conduit is configured to supply a cryo-fluid toward a tip of the probe. The probe also includes a heater positioned radially outward of an outer surface of the shell that is configured to heat the probe to perform thermal ablation.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
49.
COMBINATION PROBE FOR CRYOABLATION AND THERMAL ABLATION AND RELATED METHODS
A combination ablation probe includes a shell configured to be positioned at a target tissue in a patient and a conduit positioned inside the shell. The conduit is configured to supply a cryo-fluid toward a tip of the probe. The probe also includes a heater positioned radially outward of the conduit in the shell and at least one heat transfer element in thermal communication with the heater and the shell.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
A61B 18/08 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage à l'aide de sondes chauffées électriquement
50.
COMBINATION PROBE FOR CRYOABLATION AND THERMAL ABLATION WITH EXTERNAL HEATER
An ablation probe includes a shell configured to be positioned at a target tissue in a patient and a conduit positioned inside the shell. The conduit is configured to supply a cryo-fluid toward a tip of the probe. The probe also includes a heater positioned radially outward of an outer surface of the shell that is configured to heat the probe to perform thermal ablation.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
A61B 18/08 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage à l'aide de sondes chauffées électriquement
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A radiotherapy system includes an X-ray target configured to convert an incident electron beam into a therapeutic X-ray beam, a purging magnet configured to redirect unwanted particles emitted from the X-ray target away from the therapeutic X-ray beam, and a particle collector configured to absorb the unwanted particles subsequent to redirection by the purging magnet. The particle collector may be configured to dissipate at least 50% of the energy of the incident electron beam.
H01J 35/10 - Anodes tournantesDispositions pour anodes tournantesRéfrigération des anodes tournantes
H01J 35/14 - Dispositifs de concentration, de focalisation ou d'orientation du rayon cathodique
H01J 35/22 - Tubes conçus spécialement pour laisser passer un courant d'intensité très élevée pendant un intervalle de temps très court, p. ex. tube éclair
H01J 35/30 - Tubes, dans lesquels le point d'impact du rayon cathodique sur l'anode ou l'anticathode est déplaçable par rapport à la surface de celles-ci par déviation du rayon cathodique
H05G 2/00 - Appareils ou procédés spécialement adaptés à la production de rayons X, n'utilisant pas de tubes à rayons X, p. ex. utilisant la génération d'un plasma
H05H 9/04 - Accélérateurs linéaires à ondes stationnaires
In various embodiments, a radiation therapy method can include loading a planning image of a target in a human. In addition, the position of the target can be monitored. A computation can be made of an occurrence of substantial alignment between the position of the target and the target of the planning image. Furthermore, after the computing, a beam of radiation is triggered to deliver a dosage to the target in a short period of time (e.g., less than a second).
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
53.
SYSTEM AND METHOD TO MEASURE TEMPERATURE AND GENERATE HEAT USING A RESISTIVE MATERIAL
A heating system (100) includes a power supply (DC) that applies a first voltage to a sense resistor (RS) in series with a resistive heating material (RH) during a first time period; and a controller (CON) that determines a temperature of the resistive heating material (RH) based on a current through the sense resistor (RS) and a second voltage across the resistive heating material (RH) during the first time period. Additionally, the controller (CON) commands the power supply to provide a third voltage to the resistive heating material (RH) during a second time period, and the third voltage is based on the temperature of the resistive heating material (RH).
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
54.
SYSTEM AND METHOD TO MEASURE TEMPERATURE AND GENERATE HEAT USING A RESISTIVE MATERIAL
A heating system includes a power supply that applies a first voltage to a sense resistor in series with a resistive heating material during a first time period; and a controller that determines a temperature of the resistive heating material based on a current through the sense resistor and a second voltage across the resistive heating material during the first time period. Additionally, the controller commands the power supply to provide a third voltage to the resistive heating material during a second time period, and the third voltage is based on the temperature of the resistive heating material.
G05D 23/24 - Commande de la température caractérisée par l'utilisation de moyens électriques avec un élément sensible présentant une variation de ses propriétés électriques ou magnétiques avec les changements de température l'élément sensible ayant une résistance variant avec la température, p. ex. une thermistance
G01K 3/00 - Thermomètres donnant une indication autre que la valeur instantanée de la température
G01K 7/16 - Mesure de la température basée sur l'utilisation d'éléments électriques ou magnétiques directement sensibles à la chaleur utilisant des éléments résistifs
H05B 3/06 - Éléments chauffants combinés constructivement avec des éléments d'accouplement ou avec des supports
55.
Electronic device display screen with graphical user interface for radiotherapy machine parameter tracking
A guidance indicator includes an indicator platform having an indicator surface and a mounting portion connected to the indicator platform and supporting the indicator surface in a predetermined orientation relative to a needle of an ablation probe. The mounting portion is adapted to removably attach to a complimentary attachment post of the ablation probe.
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
A radiation system includes a modulator and at least one voltage regulator. The modulator is configured to output a voltage for operation of a magnetron and an electron gun of the radiation system. The at least one voltage regulator circuit is electrically connected between the modulator and at least one of the magnetron or the electron gun, and configured to control a magnitude of the voltage output from the modulator for operation of the magnetron and the electron gun.
H02M 1/00 - Détails d'appareils pour transformation
H02M 3/07 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des résistances ou des capacités, p. ex. diviseur de tension utilisant des capacités chargées et déchargées alternativement par des dispositifs à semi-conducteurs avec électrode de commande
58.
ABLATION PROBES WITH GUIDANCE INDICATORS TO SUPPORT LOCATION AND DIRECTION GUIDANCE SYSTEMS
An ablation probe includes an elongated needle portion comprising a distal end for positioning at a target tissue and a proximal end positioned away from the distal end and a guidance indicator positioned at the proximal end. The guidance indicator includes one or more markings or indicators to identify actual alignment of the probe relative to a preferred alignment.
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A radiotherapy system includes an X-ray target configured to convert an incident electron beam into a therapeutic X-ray beam, a purging magnet configured to redirect unwanted particles emitted from the X-ray target away from the therapeutic X-ray beam, and a particle collector configured to absorb the unwanted particles subsequent to redirection by the purging magnet. The particle collector may be configured to dissipate at least 50% of the energy of the incident electron beam.
H01J 35/10 - Anodes tournantesDispositions pour anodes tournantesRéfrigération des anodes tournantes
H01J 35/14 - Dispositifs de concentration, de focalisation ou d'orientation du rayon cathodique
H01J 35/22 - Tubes conçus spécialement pour laisser passer un courant d'intensité très élevée pendant un intervalle de temps très court, p. ex. tube éclair
H01J 35/30 - Tubes, dans lesquels le point d'impact du rayon cathodique sur l'anode ou l'anticathode est déplaçable par rapport à la surface de celles-ci par déviation du rayon cathodique
H05G 2/00 - Appareils ou procédés spécialement adaptés à la production de rayons X, n'utilisant pas de tubes à rayons X, p. ex. utilisant la génération d'un plasma
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). In an embodiment, a method comprises presenting, by a server, a first page of a first graphical user interface on the radiotherapy console associated with a radiotherapy machine in a treatment room, wherein the first graphical user interface contains a plurality of pages, each page corresponding to a stage of treatment implemented by the radiotherapy machine, and the first page corresponds to a first stage; and transitioning, by the server, the first page of the first graphical user interface to a second page of the first graphical user interface corresponding to a second stage responsive to an input of a user interacting with a second graphical interface presented on a display in the treatment room indicating that at least a predetermined portion of tasks associated with the first stage has been satisfied.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
G06F 3/0483 - Interaction avec des environnements structurés en pages, p. ex. métaphore livresque
G06F 3/04847 - Techniques d’interaction pour la commande des valeurs des paramètres, p. ex. interaction avec des règles ou des cadrans
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
H04N 7/18 - Systèmes de télévision en circuit fermé [CCTV], c.-à-d. systèmes dans lesquels le signal vidéo n'est pas diffusé
62.
METHODS OF USE OF ULTRA-HIGH DOSE RATE RADIATION AND THERAPEUTIC AGENT
Methods for treating tumors by administering FLASH radiation and a therapeutic agent to a patient with cancer are disclosed. The methods provide the dual benefits of anti-tumor efficacy plus normal tissue protection when combining therapeutic agents with FLASH radiation to treat cancer patients. The methods described herein also allow for the classification of patients into groups for receiving optimized radiation treatment in combination with a therapeutic agent based on patient-specific biomarker signatures. Also provided are radiation treatment planning methods and systems incorporating FLASH radiation and therapeutic agents.
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
A61K 31/366 - Lactones ayant des cycles à six chaînons, p. ex. delta-lactones
A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
An ablation system includes a retractable sheath including a lumen; a first electrode in the lumen; a pre-bent telescopic tube extendable from the lumen and including a second electrode, wherein the first electrode and the second electrode are configured to deliver an electric field energy to target tissue in a patient.
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
64.
PROBE SYSTEMS AND METHODS FOR IRREVERSIBLE ELECTROPORATION
An ablation system includes a retractable sheath including a lumen; a first electrode in the lumen; a pre-bent telescopic tube extendable from the lumen and including a second electrode, wherein the first electrode and the second electrode are configured to deliver an electric field energy to target tissue in a patient.
Devices, systems, and methods for planning radiosurgical treatments for neuromodulating a portion of the renovascular system may be used to plan radiosurgical neuromodulation treatments for conditions or disease associated with elevated central sympathetic drive. The renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as preganglionic positions. Target regions include the renal plexus, celiac ganglion, the superior mesenteric ganglion, the aorticorenal ganglion and the aortic plexus. Planning of radiosurgical treatments will optionally employ a graphical representation of a blood/tissue interface adjacent these targets.
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A method includes determining skin characteristics in a region of a patient. An in-treatment optical scan is performed on a region of a patient, wherein the in-treatment optical scan comprises a near infrared (NIR) energy source. A plurality of detected signals is detected from the optical scan. The skin characteristics are filtered out from the plurality of detected signals. Skeletal anatomy positioning associated with the region is determined from the plurality of signals that is filtered.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A microsphere includes a radiopaque material, and a biodegradable material such that the microsphere can be detected using medical imaging and biodegrade after being administered to a patient.
A microsphere 70 includes a radiopaque material 22, and a biodegradable material 60 such that the microsphere can be detected using medical imaging and biodegrade after being administered to a patient.
A probe 200 for performing a cryoablation treatment that includes a handle 204 with a heater 220 configured to heat a fluid and a needle connected to the handle and extending therefrom to a distal end. The needle includes a pathway configured to move the fluid from the handle toward the distal end to heat the needle.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
70.
APPARATUSES AND METHODS FOR ABLATION TREATMENTS INCLUDING PROBES WITH HANDLE HEATING
A probe for performing a cryoablation treatment that includes a handle with a heater configured to heat a fluid and a needle connected to the handle and extending therefrom to a distal end. The needle includes a pathway configured to move the fluid from the handle toward the distal end to heat the needle.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
71.
Systems and methods for real-time target validation for image-guided radiation therapy
Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 6/12 - Agencements pour détecter ou localiser des corps étrangers
A61B 6/46 - Agencements pour l’interface avec l’opérateur ou avec le patient
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
A61B 6/02 - Agencements pour établir un diagnostic dans des plans différents successifsDiagnostic stéréoscopique utilisant des radiations
72.
SETUP FOR SCOUT SCANS IN A RADIATION THERAPY SYSTEM
A method for a radiation therapy system comprises: causing a graphical representation of a movable support couch of the X-ray imaging system to be displayed, wherein the graphical representation includes one or more reference markers that each correspond to a respective physical feature of the movable support couch; receiving a first user input that includes a first position indicator that corresponds to a first boundary of an X-ray imaging region; and generating an X-ray image of the X-ray imaging region, wherein a first edge of the X-ray image corresponds to the first boundary.
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A61B 6/04 - Mise en position des patientsLits inclinables ou similaires
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
A cryosurgical system includes a probe system including a cryosurgical probe and a temperature probe; an imaging system; and a computer system operatively connected to the probe system and the imaging system and programmed with a graphical depth guide application that provides a graphical overlay on an image from the imaging system that includes a first scale of first spaced markers representing temperature of the temperature probe and a second scale of second spaced markers representing a distance from the cryosurgical probe to an imaging probe of the imaging system that provide a visual guide for locating the cryosurgical probe during surgery.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/01 - Mesure de la température de parties du corps
A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
74.
THERAPEUTIC COMBINATIONS OF TITR EFFECTORS WITH RADIATION THERAPY
This disclosure relates to therapeutic combinations of TITR effectors such as CCR8 targeting agents, radiation therapy and checkpoint inhibitors and methods of using the same for the treatment of cancer. The disclosure also relates to methods of stratifying a patient population for treating with the therapeutic combination.
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A radiation treatment planning system includes a computing device; and an interface for a user to communicate with the computing device and plan delivery of at least one radiation beam, wherein the computing device is configured to: acquire a calculated position of each of the at least one radiation beam required to treat a target tissue in a patient, wherein each of the positions is a function of a phase of a physiological cycle of the patient; determine dosages in the target tissue to be irradiated, wherein timing of some or all of the at least one radiation beam is based on the phase of the physiological cycle of the patient.
An ablation device includes a shaft and a radiofrequency (RF) emitter positioned in the shaft that delivers radiofrequency (RF) energy to create an ablation volume. The ablation device also includes an imaging sensor positioned in the tubular shaft configured to obtain imaging data of the ablation volume.
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
A61B 8/12 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores dans des cavités ou des conduits du corps, p. ex. en utilisant des cathéters
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
77.
Systems, methods, and devices for radiation beam asymmetry measurements using electronic portal imaging devices
Systems and methods for determining beam asymmetry in a radiation treatment system using electronic portal imaging devices (EPIDs) without implementation of elaborate and complex EPID calibration procedures. The beam asymmetry is determined based on radiation scattered from different points in the radiation beam and measured with the same region of interest ROI of the EPID.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
G01T 1/29 - Mesure effectuée sur des faisceaux de radiations, p. ex. sur la position ou la section du faisceauMesure de la distribution spatiale de radiations
78.
Cryosurgical probe with enhanced thermal performance
A probe and method of using a probe are disclosed. The probe may comprise a first member, a tip, a second member, and a third member. The first member may have a first and second end portions. The tip may be configured to engaged to the first member at the second end portion. The second member may be configured to extend and be positioned within the first member. The third member may be configured to be disposed outward of the second member along at least a portion of the second member, engage an inner surface of the first member, and define to least one passage between the third member and the first member. The probe may be coupled to a fluid supply and return, and fluid may flow within the probe, including within the passage defined between the first and third members.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
79.
SYSTEMS AND METHODS FOR IMAGING IN CONNECTION WITH THERMAL ABLATION TREATMENTS
An ablation device includes a shaft and a radiofrequency (RF) emitter positioned in the shaft that delivers radiofrequency (RF) energy to create an ablation volume. The ablation device also includes an imaging sensor positioned in the tubular shaft configured to obtain imaging data of the ablation volume.
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
80.
SYSTEMS AND METHODS FOR PLANNING OF CARDIAC RADIATION THERAPY
Systems (104) and methods (400) for predicting a location of a target heart region for cardiac ablation can include one or more processors generating (402) a 3D model of a heart of a patient based on medical images of the patient, and estimating (404), using the 3D model of the heart and electrophysiology data of the patient, one or more mechanical properties that drive motion of the patient's heart. The one or more processors can generate (406), using the 3D model and the one or more mechanical properties, a simulated motion pattern of the patient's heart over at least a portion of a cardiac cycle, and identify (408) a region of interest (ROI) of the heart of the patient to be radiated. The one or more processors can determine (410), using the simulated motion pattern of the heart of the patient, a location of the ROI at a predefined time instance within the cardiac cycle.
Systems and methods (400) for simulating radiation effect for cardiac ablation can include a processor generating (402) a heart simulation model configured to simulate electrical activities of the heart of the patient. The processor can determine (404) a simulated post- radiation state of the heart of the patient by adjusting the heart simulation model to account for an effect of a radiation treatment plan on simulated electrical activities of the heart of the patient. The processor can simulate (406), using the adjusted heart simulation model, the simulated post-radiation state of the heart with a stimulation to induce a heart rhythm disorder, determine (408) whether the heart rhythm disorder is induced based on electrical activities generated when simulating the simulated post-radiation state of the heart with the stimulation, and output (410) an indication of whether the heart rhythm disorder is induced. The processor can suggest modifications to the radiation plan if the heart rhythm disorder is induced.
Systems and methods for cardiac radioablation treatment and planning are disclosed. In some examples, a computing device receives a first image of a patient that was captured for treatment planning. The computing device also receives target definition data characterizing a target area of the patient for treatment. Further, the computing device receives a second image of the patient captured on the day of, and prior to, treatment. The computing device determines whether there is a risk to an organ of the patient based on the first image, the target definition data, and the second image. The computing device also provides for display an indication of risk to the patient based on the determination. For example, the indication of risk can include a treatment target region and an organ at risk region superimposed over the second image. In some examples, the indication of risk includes expected dosage levels.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
83.
SYSTEMS AND METHODS FOR PLANNING OF CARDIAC RADIATION THERAPY
Systems and methods for predicting a location of a target heart region for cardiac ablation can include one or more processors generating a 3D model of a heart of a patient based on medical images of the patient, and estimating, using the 3D model of the heart and electrophysiology data of the patient, one or more mechanical properties that drive motion of the patient's heart. The one or more processors can generate, using the 3D model and the one or more mechanical properties, a simulated motion pattern of the patient's heart over at least a portion of a cardiac cycle, and identify a region of interest (ROI) of the heart of the patient to be radiated. The one or more processors can determine, using the simulated motion pattern of the heart of the patient, a location of the ROI at a predefined time instance within the cardiac cycle.
Systems and methods for simulating radiation effect for cardiac ablation can include a processor generating a heart simulation model configured to simulate electrical activities of the heart of the patient. The processor can determine a simulated post-radiation state of the heart of the patient by adjusting the heart simulation model to account for an effect of a radiation treatment plan on simulated electrical activities of the heart of the patient. The processor can simulate, using the adjusted heart simulation model, the simulated post-radiation state of the heart with a stimulation to induce a heart rhythm disorder, determine whether the heart rhythm disorder is induced based on electrical activities generated when simulating the simulated post-radiation state of the heart with the stimulation, and output an indication of whether the heart rhythm disorder is induced. The processor can suggest modifications to the radiation plan if the heart rhythm disorder is induced.
A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by the patient. Compliance with predetermined characteristics for the field can be determined during treatment by periodically comparing the absolute dose measurements with the predetermined characteristics, which can include a predicted total dose in the field after full treatment and/or a complete irradiation area outline (CIAO). The system operator can be alerted or the irradiation automatically stopped when non-compliance is detected.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
86.
Quality assurance process for radiation therapy treatment planning
A method enables testing and evaluation of an expert human reviewer or an artificial intelligence (AI) error detection engine associated with a radiotherapy treatment planning process. Intentional errors are introduced into the output of a software module or AI engine that performs a certain step in the radiotherapy treatment planning process. The efficacy of the human or AI reviewer in detecting errors can then be evaluated or tested by determining whether the human or AI reviewer has detected the introduced error.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
87.
METHODS AND APPARATUS FOR AUTOMATICALLY DETERMINING RADIOABLATION TREATMENT RISK
Systems and methods for cardiac radioablation treatment and planning are disclosed. In some examples, a computing device receives a first image of a patient that was captured for treatment planning. The computing device also receives target definition data characterizing a target area of the patient for treatment. Further, the computing device receives a second image of the patient captured on the day of, and prior to, treatment. The computing device determines whether there is a risk to an organ of the patient based on the first image, the target definition data, and the second image. The computing device also provides for display an indication of risk to the patient based on the determination. For example, the indication of risk can include a treatment target region and an organ at risk region superimposed over the second image. In some examples, the indication of risk includes expected dosage levels.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
88.
FLUID-COOLED LOW-PROFILE MICROWAVE ABLATION PROBE WITH SPHERICAL ABLATION ZONE
A microwave ablation probe includes a cable extending in an axial direction and also includes an antenna configured to deliver Radio Frequency (RF) energy. The probe includes a shell positioned radially outward of the cable and a choke electrically coupled to an outer conductor of the cable. The probe also includes a cooling tube positioned inside the shell and positioned radially outward of the cable. The cooling tube including a first portion with a first outer diameter and a second portion with a second outer diameter. The second portion located radially outward of the choke and the second outer diameter being greater than the first outer diameter.
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
89.
APPARATUSES AND METHODS FOR COMBINATION RADIO FREQUENCY AND CRYO ABLATION TREATMENTS
A probe for performing an ablation treatment includes a shell defining an outer surface, a cooling path comprising an inflow path and a return path for a cryogen, and at least one radio frequency (RF) emitter. The probe is used to provide combination radio frequency (RF) and cryo treatments during a common procedure.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A probe for performing an ablation treatment includes a shell defining an outer surface and a cryogen supply conduit positioned within the shell. The probe also includes a flexible circuit positioned on at least a portion of the outer surface of the shell. The flexible circuit might include at least one radio frequency (RF) emitter for delivering RF energy to a target tissue.
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
91.
ABLATION PROBES INCLUDING FLEXIBLE CIRCUITS FOR HEATING AND SENSING
A probe for performing an ablation treatment includes a shell defining an outer surface and a cryogen supply conduit positioned in the shell. The probe also includes a flexible circuit positioned on at least a portion of the outer surface of the shell. The flexible circuit includes at least one radio frequency (RF) emitter for delivering RF energy to a target tissue.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
92.
DOSE-DIRECTED RADIATION THERAPY PLAN GENERATION USING COMPUTER MODELING TECHNIQUES
Provided herein are methods and systems to train and execute a computer model that uses artificial intelligence methodologies (e.g., deep learning) to learn and predict Multi-leaf Collimator (MLC) openings and control weights for a radiation therapy treatment plan.
A probe for performing an ablation treatment includes a shell defining an outer surface, a cooling path comprising an inflow path and a return path for a cryogen, and at least one radio frequency (RF) emitter. The probe is used to provide combination radio frequency (RF) and cryo treatments during a common procedure.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
94.
Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
Disclosed herein are radiotherapy systems and methods that can display a workflow-oriented graphical user interface(s). In an embodiment, a system comprises a radiotherapy machine comprising: a gantry having a screen in communication with a server, the screen configured to display a graphical user interface; and at least one camera, wherein the server is configured to present, in real time, images received from the at least one camera for display on a graphical user interface displayed on the screen.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
A61B 6/46 - Agencements pour l’interface avec l’opérateur ou avec le patient
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p. ex. pour planifier la maintenance ou les mises à jour
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
95.
GEOMETRIC ASPECTS OF RADIATION THERAPY PLANNING AND TREATMENT
Radiation treatment planning includes determining a number of beams to be directed into a target, determining directions (e.g., gantry angles) for the beams, and determining an energy level for each of the beams. The number of beams, the directions of the beams, and the energy levels are determined such that the beams do not overlap outside the target and the prescribed dose will be delivered across the entire target.
A method of performing a cryoablation treatment includes obtaining an ice formation model and preparing a cryoablation treatment plan based on the ice formation model and one or more characteristics of the target tissue. The method also includes initiating a cryoablation freezing cycle and obtaining ice formation data that describes one or more characteristics of ice being formed during the cryoablation freezing cycle. The method also includes determining a position of one or more isotherms of the ice being formed based on the ice formation data and the ice formation model.
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
97.
APPARATUSES AND METHODS FOR ASYMMETRIC ICE FORMATION DURING CRYOABLATION TREATMENTS
A method of performing a cryoablation treatment includes initiating a flow of cryogen to a tip of the cryoprobe and obtaining ice formation data characterizing a shape of ice forming at a target tissue in a patient. The method also includes comparing the ice formation data to a predetermined ice formation profile and energizing a heating portion on the cryoprobe to limit growth of ice in a first direction relative to a predetermined location on the cryoprobe while the cryogen flows to the tip of the cryoprobe.
A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
98.
Systems, methods, and devices for multi-energy ray imaging
A system can have an x-ray source that generates a series of individual x-ray pulses for multi-energy imaging. A first x-ray pulse can have a first energy level and a subsequent second x-ray pulse in the series can have a second energy level different from the first energy level. An x-ray imager can receive the x-rays from the x-ray source and can detect the received x-rays for image generation. A generator interface box (GIB) controls the x-ray source to provide the series of individual x-ray pulses and synchronizes detection by the x-ray imager with generation of the individual x-ray pulses. The GIB can control x-ray pulse generation and synchronization to optimize image generation while minimizing unnecessary x-ray irradiation.
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
G21K 1/10 - Dispositifs de diffusionDispositifs d'absorption
H05G 1/58 - Dispositions de commutation permettant de passer d'un mode de fonctionnement à un autre, p. ex. de la radioscopie à la radiographie, de la radioscopie à irradiation
H05G 1/60 - Circuits pour obtenir une série de radiophotographies ou pour la radiocinématographie
A61B 6/04 - Mise en position des patientsLits inclinables ou similaires
A61B 6/50 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des parties du corps spécifiquesAppareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des applications cliniques spécifiques
G01N 23/00 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou
G01N 23/04 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en transmettant la radiation à travers le matériau et formant des images des matériaux
A method of determining a concentration of a chemical substance in a body of a patient includes adding 402 an additive quantity of an additive material to a base quantity of a chemical substance to obtain a mixed composition having a predetermined density and delivering 404 the mixed composition to the body of the patient. The method also includes obtaining 406 an image of at least a portion of the body of the patient and determining 408 a concentration of the chemical substance in the at least a portion of the body of the patient based on the image and the predetermined density of the mixed composition.
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
100.
DEVICE AND METHOD TO INTRAOPERATIVELY MEASURE RADIOACTIVITY OF RADIOEMBOLIZATION AGENT
A device to measure radioactivity of a radioembolization material including a container 110 to receive the radioembolization material; and a dosimeter 140 that measures the radioactivity of the radioembolization material in the container while the radioembolization material is being administered to a patient.