Abrégé

The present invention relates to certain volatile organic compounds which can be detected in stool samples of individuals and be used as biomarkers in determining the probability that an individual has colorectal cancer.

Classes IPC  ?

• G01N 33/84 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des composés inorganiques ou le pH
• G01N 33/483 - Analyse physique de matériau biologique
• G01N 30/72 - Spectromètres de masse

Abrégé

The present invention relates to certain volatile organic compounds which can be detected in stool samples of individuals and be used as biomarkers in determining the probability that an individual has colorectal cancer.

Classes IPC  ?

• G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer

Abrégé

A radiation detector with a patterned structure arranged to generate charged particles in response to photons which are incident on the patterned structure. A signal generation layer is arranged to generate signal charge in response to charged particles generated in the patterned structure which are incident on the signal generation layer. A barrier layer is arranged so that the signal generation layer is positioned between the patterned structure and barrier layer and in contact with the patterned structure and barrier layer. The patterned structure and barrier layer trap the signal charge in the signal generation layer. A plurality of collectors are provided, each collector arranged to collect the signal charge trapped in the signal generation layer. The patterned structure is patterned with a varying thickness so that it has a plurality of thick regions interspersed with a plurality of thin regions, a thickness of each of the thick regions being greater than a thickness of each of the thin regions.

Classes IPC  ?

• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• G01T 1/24 - Mesure de l'intensité de radiation avec des détecteurs à semi-conducteurs
• G01T 1/29 - Mesure effectuée sur des faisceaux de radiations, p. ex. sur la position ou la section du faisceauMesure de la distribution spatiale de radiations

Abrégé

3 of the X-ray photons might interact with the detector. Hence, the disturbance to the X-ray beam is negligible.

Classes IPC  ?

• G01T 1/02 - Dosimètres
• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
• G01T 1/24 - Mesure de l'intensité de radiation avec des détecteurs à semi-conducteurs

Abrégé

A radiation beam, for example a therapeutic radiation beam such as an IMRT or VMAT X-ray beam is monitored using a Monolithic Active Pixel Sensor (MAPS) detector. Photons of the radiation beam can interact with the MAPS detector, and the radiation beam configuration can be estimated from the determined positions of the interactions. The detector is made sufficiently thin that it interacts only very weakly with the X-ray photons. For example, less than 1 in 103 of the X-ray photons might interact with the detector. Hence, the disturbance to the X-ray beam is negligible.

Classes IPC  ?

• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
• G01T 1/29 - Mesure effectuée sur des faisceaux de radiations, p. ex. sur la position ou la section du faisceauMesure de la distribution spatiale de radiations
• G01T 5/02 - Traitement des tracésAnalyse des tracés

Abrégé

A device for determining the sensitivity of the skin of a subject is provided, the device comprising a body having a head for placing in contact with the skin of the subject; vibration means for imparting a vibration to the head; a switch assembly for activating the vibration means; wherein the switch assembly is operable by a user applying pressure to the switch assembly in a direction that does not apply pressure to the skin of the subject. A method of using the device is also disclosed.

Classes IPC  ?

• A61B 5/103 - Dispositifs de mesure pour le contrôle de la forme, du dessin, de la dimension ou du mouvement du corps ou de parties de celui-ci, à des fins de diagnostic