Disclosed are anti-transient receptor potential melastatin 4 (TRPM4) antibodies and their use for treating traumatic brain injury and vascular dementia. In particular, disclosed are humanized monoclonal antibodies specific to TRPM4 and their use for treating traumatic brain injury and vascular dementia.
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
2.
A BIOMARKER FOR DETECTING STRONGYLOIDES, METHODS OF DETECTING STRONGYLOIDES AND DIAGNOSING STRONGYLOIDIASIS IN A BIOLOGICAL SAMPLE, AND A DIAGNOSTIC KIT COMPRISING THEREOF
The present invention relates to a method of refolding recombinant core streptavidin from inclusion bodies, characterised by the steps of: suspending inclusion bodies of the recombinant core streptavidin in a chaotropic agent solution having a final concentration sufficient to suppress formation of recombinant core streptavidin aggregates; heating the suspension at a temperature of 75-95 °C for 2-15 min and incubating the suspension at a temperature of 4-20°C for a minimum of 2 h to facilitate refolding of the recombinant core streptavidin.
C07K 14/36 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries provenant d'ActinomycesPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries provenant de Streptomyces (G)
C07K 1/00 - Procédés généraux de préparation de peptides
C12N 1/00 - Micro-organismes, p. ex. protozoairesCompositions les contenantProcédés de culture ou de conservation de micro-organismes, ou de compositions les contenantProcédés de préparation ou d'isolement d'une composition contenant un micro-organismeLeurs milieux de culture
4.
BIOFLOCCULANT AND BIOSORBENT DERIVED FROM DEAD CELLS OF MARINE FILAMENTOUS BACTERIUM FOR HEAVY METAL AND WASTE MATERIAL REMOVAL
The present invention relates to a method of producing an article suitable for use as a bioflocculant or a biosorbent for waste material and heavy metal removal. The method preferably comprises the steps of growing cells of a marine filamentous bacterium in a culture medium to achieve a log phase of bacteria growth (100); harvesting by way of separating the said cells of marine filamentous bacterium from the culture medium (200), wherein the step of harvesting includes centrifugation; and fixing the harvested cells of marine filamentous bacterium by subjecting the same to treatment with formaldehyde (300), wherein the said article comprises the fixed cells of marine filamentous bacterium.
A62D 3/02 - Procédés pour rendre les substances chimiques nuisibles inoffensives ou moins nuisibles en effectuant un changement chimique dans les substances par des procédés biologiques, c.-à-d. des procédés utilisant des enzymes ou des micro-organismes
There is disclosed a method of a detecting an antibody directed against a Toxoplasma infection, in particular Toxoplasma gondii: the method comprising: providing a biological sample on a surface; contacting said sample with a detector reagent in a manner to allow the reagent to move from one end to another end on said surface; wherein the detector reagent includes a combination of two recombinant proteins that detect at least one type of antibody against at least one type of Toxoplasma gondii polypeptide, in one aspect of the present invention, there is provided a lateral flow device adapted for detecting a Toxoplasma infection comprising the use of two new recombinants, G.RA7 and TgRA15.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
6.
COMPOSITION FOR INHIBITING FUNCTION OF CRYPTOCHROME
The present inventors have made it clear that a nine-membered nitrogenous fused aromatic heterocyclic compound having two nitrogen atoms and having, added thereto, a hydrogen or halogen atom and a nitro group combines with cryptochrome, which is a blue-light photoreceptor protein, to inhibit the functions of the protein. It has also been found that the compound accelerates the growth of plants when irradiated with blue light.
A01N 43/90 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant plusieurs hétérocycles déterminants condensés entre eux ou avec un système carbocyclique commun
A01P 21/00 - Régulateurs de croissance des végétaux
7.
ANTIFUNGAL COMPOSITION DERIVED FROM CLITORIA TERNATEA FLAVONOID
The present invention relates to antifungal compositions derived from Clitoria ternatea. More particularly, the present invention relates to a flavonoid composition for use as an antifungal agent, characterized in that, the composition comprises kaempferol-3-O- a-rhamnopyranosyl-(1-2)-β-10 glucopyranoside, method of manufacturing and method of use thereof. Furthermore the present invention provides a novel approach for development of a flavonoid composition comprising kaempferol-3-O-a-rhamnopyranosyl- (1-2)-β-glucopyranoside that can be combined with other drugs to form a synergistic drug combination that is capable of inhibiting fungal growth at low concentration effectively.
A monolithic on-chip fine tune spiral inductor device comprises a semiconductor substrate including a plurality of metal layers; a plurality of peripheral metal grounds being formed in one of the metal layers and disposed at peripheral of the semiconductor substrate and connected to a perfect ground; a patterned metal shield formed in central portion of the semiconductor substrate on the same metal layer forming the peripheral metal grounds, wherein the patterned metal shield comprises a plurality of isolated metal slots, and the plurality of isolated metal slots are isolated from each other and switched individually or in a group; a conductive inductor loop having one or more turns overlying the patterned metal shield and being formed on a metal layer that is different from the one forming the peripheral metal grounds; and a plurality of switches electrically coupling the peripheral metal grounds to the metal slots of the patterned metal shield.
H01L 49/02 - Dispositifs à film mince ou à film épais
H01L 27/06 - Dispositifs consistant en une pluralité de composants semi-conducteurs ou d'autres composants à l'état solide formés dans ou sur un substrat commun comprenant des éléments de circuit passif intégrés avec au moins une barrière de potentiel ou une barrière de surface le substrat étant un corps semi-conducteur comprenant une pluralité de composants individuels dans une configuration non répétitive
H01L 29/82 - Types de dispositifs semi-conducteurs commandés par la variation du champ magnétique appliqué au dispositif
9.
DIRECT HEAT SUBSTRATE-MODIFIED CHEMICAL BATH DEPOSITION SYSTEM FOR GROWTH OF ULTRA LONG ZINC OXIDE (ZnO) NANORODS AND PROCESS FOR FABRICATION OF A NANO-SIZE JUNCTION LED
A direct heat substrate-modified chemical bath deposition (DHS-MCBD) system for forming a nanostructured material film on a substrate comprises a cooling basin as a container for a cooling liquid; a deposition solution chamber as a container for a deposition solution; wherein the deposition solution chamber is disposed within the cooling basin; a heat exchanger having an inner tube that has one closed head end; a fixing means keeping a backside of a substrate in contact with an external surface of the closed head end of the inner tube of the heat exchanger and leaving a front of the substrate being submerged in the deposition solution; and a heating means disposed within the inner tube of the heat exchanger, wherein the heating means heats the closed head end of the inner tube of the heat exchanger.
C23C 18/12 - Revêtement chimique par décomposition soit de composés liquides, soit de solutions des composés constituant le revêtement, ne laissant pas de produits de réaction du matériau de la surface dans le revêtementDépôt par contact par décomposition thermique caractérisée par le dépôt sur des matériaux inorganiques, autres que des matériaux métalliques
There is disclosed a method of quantifying tremor of a subject; attaching at least one sensor on each of the two adjacent segments on the subject body; acquiring data from the sensors; whereby the multiplanar relative movements of the two adjacent hand- arm segments are captured; computing the multiplanar relative motions of the two adjacent segments to obtain a joint angle in each motion; subjecting the joint angle to a filtering process to obtain a joint angular displacement; and quantifying the tremor motion of the multiplanar relative movements of two adjacent segments using the joint angular displacement.
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61B 5/103 - Dispositifs de mesure pour le contrôle de la forme, du dessin, de la dimension ou du mouvement du corps ou de parties de celui-ci, à des fins de diagnostic
The present invention provides a method for the removal of testa from palm kernels, which comprises the steps of: (i) immersing the palm kernels in a solution of sodium carbonate (Na2CO3); (ii) heating the solution of step (i) at 85 to 95°C; (iii) removing the palm kernels from the heated solution of step (ii); (iv) immersing the palm kernels of step (iii) in a solution of hydrogen peroxide (H2O2); (v) heating the solution of step (iv) at 80 to 90°C; (vi) removing the palm kernels from the heated solution of step (v); (vii) immersing the palm kernels of step (vi) in a solution of sodium carbonate (Na2CO3) to neutralize the remaining hydrogen peroxide (H2O2) on the surface of the palm kernels; (viii) removing the palm kernels from the solution of step (vii); (ix) washing the removed palm kernels; and (x) removing the testa from the palm kernels.
T. gondii RAP domain binding protein antigen. The invention further relates to the use of the in vivo-induced antigen in the prevention or therapy of Toxoplasmosis.
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
The present invention relates to a method for the detection of Salmonella enterica (S. enterica) serovar Typhi. More particularly, the invention relates to assymetric isothermal helicase-dependent amplification of specific gene regions, coupled with detection of the amplified products by lateral flow assay.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
14.
SIMULTANEOUS DETECTION OF SALMONELLA ENTERICA SEROVARS
The present invention relates to the simultaneous detection of Salmonella enterica serovars Typhi and Paratyphi A. More particularly, the invention relates to multiplex PCR amplification of specific gene regions of Pan-Salmonella, Salmonella enterica serovars Typhi and Paratyphi A, coupled with detection of the amplified products by electrophoresis or LFA.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
15.
STRONGYLOIDES STERCORALIS PROTEIN AND/OR CORRESPONDING DNA AND RNA SEQUENCES FOR APPLICATION IN DIAGNOSIS
The present invention relates to methods of screening biological samples for the presence of Strongyloides spp. More particularly, the present invention relates to a sensitive and specific screening test for the presence of anti- Strongyloides spp antibodies, protein or nucleic acid in subjects using particular Strongyloides spp L3 stage antigens and nucleic acids encoding same which have diagnostic efficacy.
C12N 15/12 - Gènes codant pour des protéines animales
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
There is herein disclosed a compound of formula I: or a salt solvate or pharmaceutically acceptable derivative thereof, wherein R1 to R7 is as defined herein for use in the treatment of angenogenis and related conditions.
A61K 31/4184 - 1,3-Diazoles condensés avec des carbocycles, p. ex. benzimidazoles
A61K 31/454 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pimozide, dompéridone
A61P 35/02 - Agents anticancéreux spécifiques pour le traitement de la leucémie
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
Disclosed herein is a compound of formula I: where R1 to R3 are as defined herein as an anti-cancer agent or its use as an adjuvant/neo-adjuvant medicament in the treatment of cancer.
A61K 31/4184 - 1,3-Diazoles condensés avec des carbocycles, p. ex. benzimidazoles
A61K 31/454 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pimozide, dompéridone
Probiotic Composition for Treatment or Prevention of High Blood Cholesterol A composition capable of reducing total serum cholesterol in a subject upon ingestion comprising Lactobacillus fermentum strain FTDC 8312 in a pharmaceutically effective amount.
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
19.
A TWO-DIMENSIONAL ELECTROPHORESIS METHOD FOR SEPARATION OF PROTEIN COMPOUNDS
The present invention relates to a method of separating protein compounds from a sample based on inverted two-dimensional polyacrylamide gel electrophoresis (i2D- PAGE) comprising the steps of: electrophoretically separating compounds from a sample loaded into a polyacrylamide gel tube in a first dimension into discrete fractions of different molecular weights, in which the separation is conducted using gel eluted liquid fraction entrapment electrophoresis whereby each of the fractions being eluted from the gel tube is trapped in a subsequent liquid phase; collecting the liquid phase containing each of the eluted fractions; and subjecting the liquid phase to a second separation in a second dimension using an isoelectric focusing medium in the presence of electric field, in which each of the fractions are resolved according to its isoelectric point.
A compound of formula wherein R1 is selected from the group consisting of hydrogen, halogen, hydroxyl, carboxyl, alkyl of up to 5 carbon atoms, imidazolyl, piperazinyl, morpholinyl, benzyl, R4OH or R4COOH, where R4 is (CH2)m and m is an integer of from 1 to 4; R2 is selected from the group consisting of hydrogen, phenyl or 3-(2-oxopyrrolidin-l-yl) propyl; and R3 is hydrogen or alkyl of from 1-4 carbon atoms.
C07D 235/18 - BenzimidazolesBenzimidazoles hydrogénés avec des radicaux aryle liés directement en position 2
C07D 401/10 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
C07D 403/06 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne carbonée ne contenant que des atomes de carbone aliphatiques
A61K 31/4184 - 1,3-Diazoles condensés avec des carbocycles, p. ex. benzimidazoles
A61K 31/454 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pimozide, dompéridone
21.
METHOD OF FABRICATING CONCRETE BUILDING BLOCKS WITH LOW CARBON FOOTPRINT
The present invention relates to a method (100) of fabricating concrete building blocks. The method (100) consists of hydraulic densification of concrete with or without the aid of vibration forming. The method (100) further comprises the steps of: densification (104) of the zero-slump concrete mix with a predetermined forming pressure and curing (108) the concrete building blocks with the prescribed curing regime. The hydraulic densification is formed by the predetermined forming pressure ranging between 0-7000psi. Further minimization of carbon foot print of concrete block is achieved with the utilization of low carbon foot print supplementary binder material comprising of the combination of ground granulated blast furnace slag (GGBS) and pulverized fuel ash (PFA). The method (100) provides modified curing techniques and results in a material designed to have low embodied energy and low carbon footprint.
B28B 11/24 - Appareillages ou procédés pour le traitement ou le travail des objets façonnés pour faire prendre ou durcir
C04B 28/02 - Compositions pour mortiers, béton ou pierre artificielle, contenant des liants inorganiques ou contenant le produit de réaction d'un liant inorganique et d'un liant organique, p. ex. contenant des ciments de polycarboxylates contenant des ciments hydrauliques autres que ceux de sulfate de calcium
METHOD FOR THE EXTRACTION OF PALM KERNEL OIL (PKO) AND COCONUT OIL (CO) FROM VARIOUS PALM KERNEL SOURCES AND COPRA UTILIZING SUPERCRITICAL CARBON DIOXIDE (SC-CO2) TO OBTAIN DEFATTED PALM KERNEL FIBRE
This patent details a method for the extraction of palm kernel oil (PKO) and defatted palm kernel fibre from various sources of palm kernel. Three sources of palm kernel are outlined: raw palm kernel with testa, palm kernel without testa and palm kernel cake (PKC). This patent also details a method for the extraction of coconut oil (CO) from copra. Supercritical carbon dioxide (SC-CO2) is used as a solvent in the extraction process to extract the PKO and CO from the palm kernel and copra matrix. Parameters governing the SC-CO2 extraction process, namely; temperature, pressure, SC-CO2 flow rate and palm kernel particle size, are set at levels which allow the maximum amounts of PKO and CO to be extracted from the palm kernel and copra matrix. Once the extraction process is completed, two products are obtained from palm kernel: palm kernel oil and defatted palm kernel fibre. In the case of copra, two products are also obtained namely virgin coconut oil (VCO) and defatted coconut flesh fibre. Removal of the testa from palm kernel before the oil extraction step results in the extraction of colourless oil. The patent also details the testa removal process form palm kernel.
KEMENTERIAN PERTANIAN & INDUSTRI ASAS TANI (Malaisie)
Inventeur(s)
Ismail, Zhari
Beh, Hooi Kheng
Hamil, Mohd Shahrul Ridzuan
Ghafar, Gheniya
Saeed, Mohammed Ali Ahmed
Memon, Abdul Hakeem
Hashim, Suzana
Abrégé
There is provided an extract of Labisia pumila that comprises: gallic acid; caffeic acid; rutin; and one or more additional extract components, wherein on a dry weight basis: the weight/weight ratio of gallic acid to caffeic acid is from 10:1 to 75:1; the weight/weight ratio of gallic acid to rutin is from 10:1 to 50:1; and the weight/weight ratio of rutin to caffeic acid is from 1:0.3 to 1:4. There is also provided a nano-formulated liposome containing said extract and methods of preparing these compositions, as well as methods of using the same.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 127/00 - Parties de plantes contenant des feuilles ou obtenues à partir de feuilles
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
24.
IN VIVO INDUCED TOXOPLASMA GONDII PROTEIN FOR APPLICATION IN DIAGNOSIS, VACCINE AND THERAPY
The present invention relates to methods of screening biological samples for the presence of T. gondii. More particularly, the present invention relates to a sensitive and specific screening test for the presence of Toxoplasmosis in subjects by using or detecting the in vivo-induced T. gondii RAP domain binding protein antigen. The invention further relates to the use of the in vivo-induced antigen in the prevention or therapy of Toxoplasmosis.
C07D 473/24 - Composés hétérocycliques contenant des systèmes cycliques purine avec des atomes d'oxygène, de soufre ou d'azote liés directement en positions 2 et 6 un atome d'azote et un atome de soufre
26.
A METHOD OF DETECTING PORCINE MARKERS FOR IDENTIFYING PORK CONTENT IN A SAMPLE
The present invention relates to a method of detecting porcine markers for identifying a pork content in a test sample, comprising the steps of: extracting deoxyribonucleic acid (DNA) from the sample; performing polymerase chain reaction (PCR) on the extracted DNA using two pairs of primers, including a first forward primer and a first reverse primer for amplifying a target porcine DNA sequence, and a second forward primer and a second reverse primer (as an internal control) for amplifying a target gene sequence; then subjecting the amplified sequence to electrophoresis to detect the presence of porcine markers in the sample; characterized in that: the first forward primer comprises SEQ ID NO:1, the first reverse primer comprises SEQ ID NO:2, the second forward primer comprises SEQ ID NO:3, and the second reverse primer comprises SEQ ID NO:4.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C07H 1/04 - Introduction de radicaux d'acide polyphosphorique
27.
COMPOUNDS AND METHODS FOR THE TREATMENT OF MICROBIAL INFECTION(S)
MALAYSIAN INSTITUTE OF PHARMACEUTICALS AND NUTRACEUTICALS (Malaisie)
Inventeur(s)
Wahab, Habibah A.
Hariono, Maywan
Kamarulzaman, Ezatul Ezleen
Abrégé
The present invention relates to compounds useful in methods of treating at least one microbial infection, such methods and uses of said compounds, pharmaceutical formulations comprising said compounds, and/or synthetic processes. The compounds have the general formula (I) wherein R1 is H, N02, Br, I, NHC2H4OH, NHC(=NH)NH2; NH2; R2 is H, CH(CH3)2) S02-4-C6H4F or SO2-4-C6H4-OCH3; R3 is H or NO2; and R4 is CHO or CH=CHC(0)OR5, wherein R5 is CH2CH2CH2CH3, or more preferably H, CH3, CH2CH3 or CH2CH2CH3.
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus
28.
A METHOD FOR PRODUCING A THERMALLY STABLE FLUID LOSS REDUCING AGENT FOR WATER-BASED DRILLING FLUID
A method for preparing a lignin grafted polyepoxide (LGPEX) for the use as a fluid loss reducing agent in drilling fluid comprising the steps of preparing a mixture consists of one or more materials selected from acrylic acid, acrylic acid salt, dimethylacrylamide, 2-acrylamido-2-methylpropanesulfonic acid, acrylonitrile, sodium-grafted-polyethylene oxide and polyacrylic acid-sodium-grafted-polyethylene oxide in an alkaline solution; reacting the mixture with the lignin by stirring and heating at a temperature between 88 to 105 °C in the presence of an acid catalyst under a nitrogen atmosphere. The method substantially provides a fluid loss reducing agent which could impart relatively high thermal stability characteristic in association with a water-based drilling fluid. Particularly, the drilling fluid could exhibit thermal stability up to 250 °C.
C09K 8/487 - Additifs régulant les pertes de fluideAdditifs pour réduire ou empêcher la perte de circulation
C09K 8/20 - Composés organiques naturels ou leurs dérivés, p. ex. polysaccharides ou dérivés de la lignine
C08H 7/00 - LignineLignine modifiéeProduits dérivés à haut poids moléculaire
C08L 97/02 - Matériau lignocellulosique, p. ex. bois, paille ou bagasse
D06M 14/02 - Polymérisation par greffage de monomères, contenant des liaisons non saturées carbone-carbone, sur des fibres, fils, filés, tissus ou articles fibreux faits de ces matières sur des matières d'origine naturelle
29.
PRODUCTION METHOD FOR POLYHYDROXYALKANOATE USING ONLY PHOTOSYNTHESIS
As a result of introducing genes that encode acetoacetyl-CoA synthase in cyanobacteria, the present invention succeeds in producing PHA at a significantly high level of efficiency even when cultivation is performed in an inorganic salt culture solution that does not contain sugar and photosynthesis is performed using CO2 within air as a carbon source.
C12N 1/13 - Algues unicellulairesLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12N 15/00 - Techniques de mutation ou génie génétiqueADN ou ARN concernant le génie génétique, vecteurs, p. ex. plasmides, ou leur isolement, leur préparation ou leur purificationUtilisation d'hôtes pour ceux-ci
The present invention relates to a method for detection of depolymerase activity of a lipase, characterized by contacting the lipase to a transparent polymer film, wherein the transparent polymer film comprises a polyhydroxyalkanoate polymer. The surface of the transparent polymer film having a hydrolysis mark is scanned against a dark background to obtain an image of the transparent polymer film with a dark background. The scanned image of the transparent polymer film is colour inverted to obtain an image with light background; and analysing the hydrolysis mark on the image of the transparent polymer film using densitometry analysis, wherein the lipase is determined to have depolymerase activity against the transparent polymer film if the density of an area with the hydrolysis mark is higher than the density of the area without the hydrolysis mark.
C12Q 1/34 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase
G01N 9/24 - Recherche du poids spécifique ou de la densité des matériauxAnalyse des matériaux en déterminant le poids spécifique ou la densité en observant la propagation de l'onde ou de la radiation des particules à travers le matériau
There is provided a method of detecting at least one target analyte in a sample, the method comprising the steps of: a) contacting the sample with a first capturing reagent comprising at least one thermostabilizing reagent for capturing the target analyte, and a first tagging reagent comprising at least one thermostabilizing reagent for tagging the target analyte, to form a target complex; b) purifying the target complex; and c) detecting the presence of the target complex; wherein the presence of the target complex indicates the presence of the target analyte in the sample, and wherein the capturing reagent and the tagging reagent are stable at ambient temperature.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
The invention relates to a method for making an eco-friendly mat comprising: providing a banana stem; peeling the banana stem to obtain individual banana stem sheaths and scoring the inner surface of the banana stem sheaths to form banana stem sheets; soaking the banana stem sheets in water at room temperature; cold-pressing the mat assembly at room temperature and pressure removing the mat assembly from the cold pressing procedure; hot pressing the mat assembly at a higher temperature and a pressure; brushing the hot press unit of the mat assembly with a solution of glycerol; conducting final hot-pressing; and removing the mat assembly and cooling. The present invention also relates to an eco-friendly mat comprising: two layers of banana stem sheets; two pieces of plastic screens sandwiching the banana stem sheets; and two pieces of cotton felts sandwiching the banana stem sheets and the plastic screens, wherein the sandwich of the materials is pressed to form a piece of mat.
The present invention relates to a method for adding photoluminescent pigment to glass structure to provide glow-in-the-dark effects on the glass. The present invention comprising: providing raw materials for forming glass (100); undertaking process of forming first layer of glass (103); characterized in that applying a layering technique to add photoluminescent pigment on the first layer of glass (200).
C03C 4/12 - Compositions pour verres ayant des propriétés particulières pour verre luminescentCompositions pour verres ayant des propriétés particulières pour verre fluorescent
C09K 11/00 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes
B32B 17/06 - Produits stratifiés composés essentiellement d'une feuille de verre ou de fibres de verre, de scorie ou d'une substance similaire comprenant du verre comme seul composant ou comme composant principal d'une couche adjacente à une autre couche d'une substance spécifique
F21K 2/00 - Sources lumineuses non électriques utilisant la luminescenceSources lumineuses utilisant l'électrochimioluminescence
A wireless production monitoring system for wirelessly transmitting production data of a plurality of production lines (40) within a manufacturing plant to a remote server (50) via a wireless access point (80) so that the manufacturing plant's production can be monitored remotely. The wireless production monitoring system including a plurality of detection and data input collection modules, (10) for detecting and collecting production line (40) related data, including at least one RFID tag ( 10c); a data transmission module (70) comprising a plurality of RFID readers (30), a plurality of wireless routers (20) and a wireless access point (80) that enable wireless communication of said production line (40) related data between anyone of the plurality of detection and data input collection modules (10) to a data management module (207); the data management module (207) including a local host (201) serving as a web based server that includes a web based data acquisition system (200).
A method for preparing an immunogen to trigger production of anti(9-methoxy corynantheidine) antibody for a use in detecting presence of mitragynine in humans.
C07K 1/113 - Procédés généraux de préparation de peptides par modification chimique de peptides précurseurs sans changement de la structure primaire
C07D 455/00 - Composés hétérocycliques contenant des systèmes cycliques quinolizine, p. ex. alcaloïdes de l'émétine, protoberbérineDérivés alkylènedioxy des dibenzo [a, g] quinolizines, p. ex. berbérine
G01N 33/577 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet faisant intervenir des anticorps monoclonaux
G01N 33/94 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des narcotiques
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
36.
DEVICE AND METHOD FOR DETECTION OF NUCLEIC ACID(S)
There is provided a test strip and methods for detecting nucleic acids that have been molecularly amplified. The test strip may comprise: at least one sample application zone for applying the sample to the test strip; at least one detection zone comprising at least one immobilised probe complementary to the target nucleic acid; and at least one label zone comprising at least one releasably immobilised labelled conjugate for visual detection of the target nucleic acid.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
37.
COMPOSITION FOR THE TREATMENT AND/OR PREVENTION OF FATTY LIVER DISEASE
There is provided at least one method of treating, preventing, ameliorating, reducing or delaying the onset of fatty liver disease (FLD) using tocotrienol or derivative thereof or a mixture thereof.
A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A handle adaptor arranged to mount a handle to a vibrating power tool said adaptor comprising: a vibration isolator, said vibration isolator including at least two vibration dampers each for damping vibration along a respective axis; wherein said respective axes corresponding to said vibration dampers are perpendicular to each other.
The present invention relates to a process for producing activated carbon fibres (ACF) from empty fruit brunch (EFB) fibres. The process includes the steps of: (i) washing EFB fibres with nitric acid (HNO3) and followed by washing of the EFB fibres with deionized (DI) water and drying of the EFB fibres. This step is essential for removal of any adsorbed inorganic materials; (ii) mixing the EFB fibres obtained from step (i) with sulphuric acid (H2S44); (iii) subjecting the EFB fibres obtained from step (ii) to a carbonization process; (iv) heating chars obtained from step (iii) in nitrogen gas environment up to temperature between 600 to 1200 °C and holding chars obtained from step (iv) at a temperature between 600 to 1200°C in carbon dioxide gas (CO2) environment for a period between 1 to 24 hours and followed by cooling step in nitrogen gas environment.
D01F 9/12 - Filaments de carboneAppareils spécialement adaptés à leur fabrication
D01F 9/16 - Filaments de carboneAppareils spécialement adaptés à leur fabrication par décomposition de filaments organiques à partir de produits d'origine végétale ou de leurs dérivés, p. ex. à partir de l'acétate de cellulose
Methods for producing methadone and its resolution to produce (R)-6-dimethylamino-4,4-diphenylheptan-3-one ((R)- methadone). Such methods producing first the precursor compound 4-(dimethylamino)-2,2-diphenylpentanitrile. Oxidation of 4-(dimethylamino)-2,2-diphenylpentanitrile with ethyl magnesium halide and hydrolysis with of the complex to form 6-dimethylamino-4,4-diphenylheptan-3-one. Resolution to the (R)-isomer is effected by reaction with a bromocamphor salt. Once isolated the (R)-isomer is crystallised.
C07C 221/00 - Préparation de composés contenant des groupes amino et des atomes d'oxygène, liés par des liaisons doubles, liés au même squelette carboné
C07C 225/10 - Composés contenant des groupes amino et des atomes d'oxygène, liés par des liaisons doubles, liés au même squelette carboné, au moins un des atomes d'oxygène, liés par des liaisons doubles, ne faisant pas partie d'un groupe —CHO, p. ex. aminocétones ayant des groupes amino liés à des atomes de carbone acycliques du squelette carboné le squelette carboné étant saturé et contenant des cycles avec des atomes d'oxygène, liés par des liaisons doubles, liés à des atomes de carbone ne faisant pas partie de cycles
C07C 253/30 - Préparation de nitriles d'acides carboxyliques par des réactions n'impliquant pas la formation de groupes cyano
41.
RECOMBINANT ALPHA AMYLASE AND THE PRODUCTION THEREOF
The invention relates to a method for producing α-amylase from Geobacillusthermoleovorans CCB_US3_UF5 wherein the steps includes: (a) preparing a sample with the Geobacillusthermoleovorans CCB_US3_UF5 to obtain the α-amylase gene; (b) amplifying the α-amylase gene using primers of Forward(NW-Alp-Nde I-F) - CCC CAT ATG GAA AAA GAA GAA CGG ACG TGG and Reverse(NW-Alp-Xho I-R) - CCC CTC GAG TTA TGT TTT CTC CCG TAG CTT by means of polymerase chain reaction; (c) cloning the amplified gene to obtain a cloned plasmid with the α-amylase gene; (d) transforming the cloned plasmid into competent cells; (e) cultivating the competent cells for α-amylase expression; and (f) extracting and purifying the α-amylase. The α-amylase gene and the α-amylase protein is at least 90% identical to the sequence as set forth in SEQ. ID 1 and SEQ. ID 2 respectively. The recombinant His-tagged and untaggedthermostableα-amylaseis able to digest soluble starch at a range of pH 4.0 to p H 8.0 and at a temperature range of 40° C to 80° C. The α-amylase from GeobacillusthermoleovoransCCB_US3_UF5 comprises the sequence as set forth in SEQ. ID and SEQ. ID 2 or a functional fragment thereof and can be used in various industries such as the baking industry.
A system for identifying presence of polynucleotides of interest from a sample comprising a sensing platform having a working electrode (102), a reference electrode (103) and a counter electrode (104) which are electrically connected to a connection port (101) and that the electrodes (102, 103, 104) have a top and a bottom layer respectively made of gold (111) and nickel (112), wherein surface of each layer of gold (111) is anchored with one or more oligonucleotide probes to readily hybridize with a substantially complementary polynucleotide in the sample; an operating circuit (105) provided with a receptive port to adaptably communicate with the sensing platform by mating with the connection port (101) and configured to measure a signal indicative of hybridization of the sensing platform; a display (108) connected to the operating circuit to acquire and show electrical readings of the operating circuit (105); wherein presence of polynucleotides of interest in the sample is identified by detecting the signal upon hybridization onto the probes; characterized in that the layer of nickel (112) is in between the layer of gold (111) and a base layer (109) made of copper (113) where the sensing platform and operating circuit are fabricated on.
The present invention relates to an isolated polynucleotide encoding an enzyme for catalyzing biosynthesis, conversion or utilization of prenyl-pyrophosphate for rubber biosynthesis in the plant of Hevea brasiliensis, comprising nucleotide sequence set forth in SEQ ED NO. 1, SEQ ID NO. 3, SEQ ID NO. 5, SEQ ID NO. 7, SEQ ID NO. 9 or any complementary sequence thereof. The present invention also relates to an isolated polypeptide encoded by the polynucleotide; a recombinant gene construct comprising the polynucleotide; a transformant; and a transgenic plant comprising the recombinant gene construct, with enhanced biosynthesis and accumulation of polyisoprenoids; as well as a method for enhancing biosynthesis and accumulation of polyisoprenoids comprising the steps of cloning the gene construct comprising the polynucleotide and expressing the gene construct in a host cell.
C12N 15/29 - Gènes codant pour des protéines végétales, p. ex. thaumatine
C12N 15/52 - Gènes codant pour des enzymes ou des proenzymes
A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique
44.
A METHOD FOR REGULATING CYTOSOLIC ISOPRENOID BIOSYNTHESIS IN HEVEA BRASILIENSIS
The present invention discloses an isolated polynucleotide encoding an enzyme for catalyzing cytosolic biosynthesis of isopentenyl diphosphate, dimefhylallyl diphosphate or the combination thereof in the plant of Hevea brasiliensis, comprising nucleotide sequence set forth in SEQ ID NO. 1, SEQ ID NO. 3, SEQ ID NO. 5, SEQ ID NO. 7, SEQ' ID NO. 9 or any complementary sequence thereof; and a method for enhancing cytoplasmic availability and functionality of the enzyme, comprising the steps of predicting catalytic domain, signal peptide or membrane-spanning domain of the enzyme; introducing a point mutation to the predicted catalytic domain, signal peptide or membrane-spanning transmembrane domain; and expressing the mutated catalytic domain, signal peptide or membrane-spanning transmembrane domain in a plant cell, tissue or organ of Hevea brasiliensis. The present invention also relates to an isolated polypeptide encoded by the polynucleotide, a recombinant gene construct comprising the polynucleotide, a transformant and a transgenic plant comprising the recombinant gene construct, with enhanced production of cytosolic isoprenoid towards rubber production.
A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique
C12N 15/29 - Gènes codant pour des protéines végétales, p. ex. thaumatine
C12N 15/52 - Gènes codant pour des enzymes ou des proenzymes
45.
A METHOD FOR REGULATING PLASTIDIAL ISOPRENOID BIOSYNTHESIS IN HEVEA BRASILIENSIS
The present invention relates to an isolated polypeptide for catalyzing plastidial biosynthesis of isopentenyl diphosphate, dimethylallyl diphosphate or the combination thereof in the plant of Hevea brasiliensis, comprising amino acid sequence set forth in SEQ ID NO. 2, SEQ ID NO. 4, SEQ ID NO. 6, SEQ ID NO. 8, SEQ ID NO. 10 or SEQ ID NO. 12; and a method for catalyzing the biosynthesis of isopentenyl diphosphate, dimethylallyl diphosphate or the combination thereof for enhancing the biosynthesis of natural rubber from its precursors. The present invention also relates to an isolated polynucleotide encoding the polypeptide, a recombinant gene construct comprising the polynucleotide, a transformant and a transgenic plant comprising the recombinant gene construct.
A method of detecting presence of a primary antibody reactive against rubber allergenic polypeptides in a serum sample comprises the steps of providing a platform fixed with rubber allergenic polypeptides having at 70% sequential amino acids as setting forth in SEQ ID No. 2, SEQ ID No. 4, SEQ ID No. 6, SEQ ID No. 8, SEQ ID No. 10. SEQ ID No. 12, SEQ ID No. 14, or SEQ ID No. 16; bringing into contact the serum with the fixed rubber allergenic polypeptides to feasible binding of the primary antibody available in the serum onto the rubber allergenic polypeptides; reacting a secondary antibody towards any bound primary antibody upon washing off the serum, wherein the secondary antibody is capable of binding onto the primary antibody and anchored with a detectable moiety; and detecting presence of the detectable moiety to confirm available of the primary antibody in serum upon removal of the unreacted secondary antibody.
A control circuit capable of proportionally supplying electrical current from an alternate current power supply to a glass pane coated with transparent conductive oxides on refrigerator comprises a triode for alternating current (TRIAC) electrically gating the voltage to be supplied to the glass pane; and a micro-controller configured to fire an electrical pulse to the TRIAC after a pre-determined delayed duration once detecting zero crossing of each phase of the alternate current; wherein the TRIAC allows electrical current conduction at each phase of the alternate current to the glass pane upon receiving the electrical pulse and the total electrical current supplied to the glass pane is inversely related to the pre-determined delayed duration.
The present invention discloses a composition consisting essentially of an amount of a compound effective for inhibiting colorectal cancer cell growth, the compound having the following structure isolated and purified from Sandoricum koetjape plant extract.
A61K 31/575 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne d'au moins trois atomes de carbone, p. ex. cholane, cholestane, ergostérol, sitostérol
The present invention provides a magnetically coupled dynamometer (10) that dispenses with the need to physically couple said dynamometer (10) to the shaft (30) of aforementioned rotating machine (20) and facilitate the rapid testing of multiple rotating machines (20) by inherently facilitating the rapid removal and replacement of a rotating machine (20). The magnetically coupled dynamometer (10) apparatus of the present invention comprising of a first portion (10a) that includes a conductive disk (40) mounted on a rotating shaft (30) of a rotating machine (20) that is placed in close proximity to a second portion (10b) that includes an induction electromagnet (50), a load cell (60) configured to provide a measure of the force acting on the induction electromagnet (50) due to the interaction of the magnetic fields of the disk (40) and the induction electromagnet (50) and provides a measure of the torque generated by the rotating shaft (30) of the rotating machine (20), a speed sensor (70) configured to provide a measure of the rotational speed of the rotating machine's shaft (30) and a base (80) that serves to support the rotating machine (20) fitted with the first portion (10a) and the induction electromagnet (50), load cell (60) and the speed sensor (70).
The present invention discloses a wideband dielectric resonator antenna (1 ) with an exceptionally wide bandwidth of 2.30GHz and a center frequency of 8.19GHz. The wideband dielectric resonator antenna (1) of the present invention comprising of a dielectric resonator (4) made up of a plurality of vertically oriented slabs of dielectric material (4a) that are laterally stacked and disposed on strip of conductive material (3) that forms a portion of a micro-strip transmission line (7), aforementioned micro-strip transmission line (7) serving to feed electromagnetic signals that originate from a transmission circuit to the dielectric resonator (4) via SMA port connector (6). The exceptionally wide bandwidth of the wideband dielectric resonator antenna (1 ) of the present invention is attributed to the use of a plurality of vertically oriented, laterally stacked RT/duroid 6010LM dielectric material (4a) to form the dielectric resonator (4).
The present invention relates to an isolated antigenic protein of Helicobacter pylori. More specifically, the present invention provides an isolated antigenic protein of Helicobacter pylori selected from a group comprising polypeptides having a molecular weight of 13 kDa, 25 kDa, 29 kDa, 30 kDa, 31 kDa or 1 18 kDa, or any combination thereof, wherein said antigenic protein is in substantially purified form. The present invention also relates to a use of said isolated antigenic protein of Helicobacter pylori in vaccines and diagnostic kits for treatment of Helicobacter pylori infection in humans.
The present invention provides a method for preparing sintered nanostructured carbonated hydroxyapatite (CHA). The method comprises mixing of CHA powders with a sintering aid to form a mixture, dry pressing the mixture, sintering the mixture at a first predetermined temperature for a first predetermined time period in air atmosphere without provision of external C02 gas to form nanostructured CHA, cooling the nanostructured CHA to a second predetermined temperature, wherein the second predetermined temperature is lower than the first predetermined temperature, and refurbishing the nanostructured CHA with wet C02 gas for a second predetermined time period. The present invention also provides a sintered nanostructured carbonated hydroxyapatite (CHA). The present invention further provides a system for producing sintered nanostructured carbonated hydroxyapatite (CHA).
A method for manufacturing palm oil fuel ash based high strength concrete, comprising the steps of pyrolyzing wastes derived from palm oil production at a controlled temperature; combusting the pyrolyzed wastes to obtain the palm oil fuel ash with desired physical and chemical properties; modifying pozzolanic properties of the palm oil fuel ash through a systematic experimental investigation to obtain the modified palm oil fuel ash; and producing high strength concrete by using the modified palm oil fuel ash as a supplemental cementitious material in the concrete at a predetermined replacement ratio. The pyrolyzation step is preferably carried out at a temperature between 400°C and 700°C, either in the absence or the presence of oxygen, to provide a modified palm ash containing pozzolan with a particle size from 10 μπι to 20 μπι. The modified palm oil fuel ash may be used in a ratio of 1 : 10 to 3: 10 to other cementitious materials in the concrete.
C04B 28/02 - Compositions pour mortiers, béton ou pierre artificielle, contenant des liants inorganiques ou contenant le produit de réaction d'un liant inorganique et d'un liant organique, p. ex. contenant des ciments de polycarboxylates contenant des ciments hydrauliques autres que ceux de sulfate de calcium
B09B 3/00 - Destruction de déchets solides ou transformation de déchets solides en quelque chose d'utile ou d'inoffensif
54.
A GEOMETRIC METHOD FOR PREDICTING LANDSLIDE DISASTE
The present invention provides a method for predicting a landslide disaster on a specific area, the method comprising pre-determining data having variables of the specific area that are associated to landslide, wherein the variables includes geological data, hydrological data, and landslide historical data; pre-classifying each of the variables with specific indicators and boundaries, wherein the specific indicator is associated to a rating of the respective variables, wherein the boundaries includes an upper and lower boundary for each of the variables; generating a mathematical multi¬ dimensional index for the specific area, wherein the mathematical multi-dimensional index comprises visualizations and rankings of the specific areas through a Cartesian co-ordinate, wherein the Cartesian co-ordinate represents a risk ratio of the specific indicator; ranking the specific areas based on the Cartesian co-ordinates; and identifying a disaster risk landslide area based on the rankings of the specific areas generated from the mathematical multi-dimensional index.
An in vitro method of diagnosing and/or treating at least one subject as having or as being at risk of having Entamoeba histolytica (E. histolytica) infection, the method comprising detecting the presence of at least one E. histolytica protein, fragment, variant or mutant thereof in a serum sample from the subject, wherein the presence of the protein, fragment, variant or mutant thereof is indicative of the subject having or as being at risk of having E. histolytica infection.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
A61P 33/02 - Antiprotozoaires, p. ex. pour le traitement de la leishmaniose, de la trichomonase, de la toxoplasmose
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
A transgenic plant of Hevea brasiliensis with reduced lignin content characterized in that expression of at least one nucleic acid template containing sequence selected from SEQ ID NOs. 1-13 in at least one cell is down-regulated. These sequences encode coniferyl alcohol glucosyltransferases and coniferin-hydrolyzing β- glucosidases identified in H. brasiliensis.
C12N 9/44 - Hydrolases (3.) agissant sur les composés glycosyliques (3.2) agissant sur les liaisons alpha-glucosidiques-1, 6, p. ex. iso-amylase, pullulanase
C12N 15/29 - Gènes codant pour des protéines végétales, p. ex. thaumatine
A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
57.
A METHOD OF REGULATING MONOLIGNOLS POLYMERIZATION ON CELL WALLS OF THE PLANT HEVEA BRASILIENSIS AND A TRANSGENIC PLANT ACQUIRED THEREOF
A method of reducing polymerization of monolignols onto secondary cell walls of at least one tissue type in the plant Hevea brasiliensis comprising the steps of down-regulating expression of at least one nucleic acid template containing a sequence set forth in any of SEQ ID NOs: 1-18 in cells of the tissue. The application also relates to the sequences themselves which encode cationic peroxidases, anionic peroxidases, rubber peroxidases and laccases.
A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
58.
A METHOD FOR REGULATING BIOSYNTHESIS OF MONOLIGNOLS
A method for reducing the synthesis of monolignols in cytoplasm of the plant of Hevea brasiliensis, comprising the step of down-regulating expression of a nucleic acid template containing at least one nucleotide sequence set forth in SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3, SEQ ID NO. 4, SEQ ID NO. 5, SEQ ID NO. 6, SEQ ID NO. 7, SEQ ID NO. 8, SEQ ID NO. 9, SEQ ID NO. 10, SEQ ID NO. 1 1 or SEQ ID NO. 12 in at least one cell. Also claimed are nucleotide sequences encoding phenylalanine ammonia-lyase 1 (PALI), phenylalanine ammonia-lyase 2 (PAL2), cinnamate 4-hydroxylase (CH4), coumarate 3-hydroxylase 1 (C3H1), coumarate 3-hydroxylase 2 (C3H2), caffeic acid/5-hydroxyconiferaldehyde O-methyltransferase (COMT), Hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl transferase (HCT), ferulate 5-hydroxylase (F5H), 4-coumarate CoA ligase (4CL), 4-coumarate caffeoyl-CoA O-methyltransferase (CCoAOMT), 4-coumarate cinnamoyl coenzyme A reductase (CCRl), and 4-coumarate cinnamyl alcohol dehydrogenase (CAD) enzymes, all from Hevea brasiliensis.
The present invention provides a system (1 ) and method for assessing the positional errors of an axially moving body on a predefined plane of movement. The system (1 ) comprises of a metrological tool or device (1a) for assessing the measurement errors of the position of a moving body in six degrees of freedom, the device (1a) being adapted for movement with the moving body and is further adapted to receive a beam of electromagnetic radiation (5) and consequently provides an indication of relative movement between the beam (5) and the moving body in one or both of two directions transverse to the beam (5), the directions may be at right angles to each other and/or are at right angles to the beam (5). Aforementioned metrological device (1a) being used in conjunction with a linear scale used to indicate the length of travel of the axially moving body. In addition the system (1 ) further includes an apparatus (25) for monitoring and providing a measure of the pointing instability of a beam (5) of electromagnetic radiation; and an apparatus for monitoring and providing a measure of the of the tilt of aforementioned moving body moving along an axial direction with reference to the plane of movement of the moving body.
G01B 11/14 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la distance ou la marge entre des objets ou des ouvertures espacés
G01B 11/26 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer des angles ou des cônesDispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour tester l'alignement des axes
An isolated polynucleotide comprising nucleotide sequence set forth in SEQ ID NO: 1 or SEQ ID NO: 2 encoding cis-prenyl transferase of the plant Hevea brasiliensis.
C12N 15/29 - Gènes codant pour des protéines végétales, p. ex. thaumatine
C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
61.
UNDECAPRENYL PYROPHOSPHATE SYNTHASE FROM THE PLANT HEVEA BRASILIENSIS
An isolated polypeptide for catalyzing the synthesis of undecaprenyl pyrophosphate in the plant of Hevea brasiliensis comprising amino acid sequence set forth in SEQ ID NO: 3 or SEQ ID NO: 4.
A method of reducing production of lignin content in the plant of Hevea brasiliensis comprises the step of down-regulating expression of at least one nucleic acid template containing sequence SEQ ID No.l, SEQ ID No.2, SEQ ID No.3 and SEQ ID No.4 in at least one cell.
The present invention relates to an emergency equipment for use in safely securing an injured limb of a person. The said emergency equipment is a portable and compact splint and wherein said emergency equipment (10) comprises of a top portion (12), a pair of spring wire and button (14), a pair of upper supporting members (16), a pair of locking means (18), a pair of lower supporting means (20), a pair of pins (22), a pair of bottom screws (24), a pair of fastening screws and nuts (26), a bottom portion (28) and a foot plate (30). The emergency equipment comprises of four main parts categorized as the length adjustment mechanism and locking means (18), the top portion (12), the bottom portion (28) and an attachment of the foot plate (30).
A pharmaceutical composition for inhibiting proliferative activity of osteosarcoma and tongue carcinoma cells comprising an extract derived from Streblus spp.
An apparatus for production of carbon nanotubes, comprising a reaction chamber, arranged to receive at least one catalyst and a carbon precursor; and a rotatable helical structure within said reaction chamber arranged to carry the at least one catalyst and arranged to traverse the at least one catalyst along the length of the reaction chamber.
The present invention discloses an engineered cementitious composite comprising a mortar matrix reinforced with polymeric fibres, in which the mortar matrix includes hydraulic cement, ground palm oil fuel ash, fine aggregates, a viscosifying agent and a water-reducing agent. An optimum design is used that involves producing palm oil fuel ash with the desired physical and chemical properties and grain size, along with the optimum mixing proportions that incorporate measures of palm oil fuel ash as a supplementary cementitious material, and polymeric fibres at a preferred fibre volume fraction, thereby reducing the level of cement use without compromising the mechanical and physical properties of the composite. This formulation provides a cost-effective alternative for producing durable concrete structures while promoting sustainable development and material greenness.
C04B 20/00 - Emploi de matières comme charges pour mortiers, béton ou pierre artificielle prévu dans plus d'un groupe et caractérisées par la forme ou la répartition des grainsTraitement de matières spécialement adapté pour renforcer leur propriétés de charge dans les mortiers, béton ou pierre artificielle prévu dans plus d'un groupe de Matières expansées ou défibrillées
C04B 28/02 - Compositions pour mortiers, béton ou pierre artificielle, contenant des liants inorganiques ou contenant le produit de réaction d'un liant inorganique et d'un liant organique, p. ex. contenant des ciments de polycarboxylates contenant des ciments hydrauliques autres que ceux de sulfate de calcium
67.
PORTABLE RADIO FREQUENCY IDENTIFICATION READER FOR REAL TIME LOCATION SYSTEMS
The present invention discloses a portable RFID reader device (102) that comprises of a first transceiver (110) integrated with a first antenna (112) and a second transceiver (118) integrated with a second antenna (120) housed within a common housing (104) and in communication with one another via a physical electrical interconnection. The first transceiver (110) being an RFID transceiver in combination with a portion of a controller (108) designated for RFID reader functionality perform the functions of a RFID reader (106). The second transceiver (118) being an end device transceiver is in combination with a portion of a controller (116) designated for performing computations related to the information received by the end device transceiver (118) from a host (134) from an end device (114).
Accordingly, the invention discloses compounds with enhanced bioavailability for the prevention and treatment of anti-human immunodeficiency virus (HIV), anti- tuberculosis (TB), anti-Alzheimer or anti-cancer. The invention also discloses the method in synthesizing these compounds wherein the steps includes mixing curcumin, isatin derivatives or ninhydrin and pipecolinic acid in 20 m L methanol. The mixture was then refluxed with a solvent on a water bath and excess solvent was removed under vacuum. The residue subjected to flash column chromatography using petroleum ether: ethyl acetate mixture (4:1) as eluent to afford the product. The ratio for curcumin: isatin derivative/ninhydrin: pipecolinic acid is 1:1:2 and 1:2:4.
A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
A61P 31/06 - Agents antibactériens pour le traitement de la tuberculose
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 31/18 - Antiviraux pour le traitement des virus ARN du HIV
Accordingly, the invention discloses compounds with enhanced bioavailability for the prevention and treatment of anti-human immunodeficiency virus (HIV), anti-tuberculosis (TB), anti-Alzheimer or anti-cancer, with the following formulas: The invention also discloses the method in synthesizing these compounds wherein the steps includes mixing curcumin, isatin derivatives or ninhydrin and sarcosine or phenyl glycine in 20 mL methanol. The mixture was then refluxed with a solvent on a water bath and excess solvent was removed under vacuum. The residue subjected to flash column chromatography using petroleum ether: ethyl acetate mixture (4:1) as eluent to afford the product. The ratio for curcumin:isatin derivative/ninhydrin:sarcosine/phenyl glycine is 1:1:2 and 1:2:4.
C07D 209/96 - Systèmes cycliques condensés en spiro
A61K 31/403 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des carbocycles, p. ex. carbazole
A61K 31/407 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des systèmes hétérocycliques, p. ex. kétorolac, physostigmine
A61P 31/06 - Agents antibactériens pour le traitement de la tuberculose
A61P 31/18 - Antiviraux pour le traitement des virus ARN du HIV
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
Accordingly, the invention discloses compounds with enhanced bioavailability for the prevention and treatment of anti-human immunodeficiency virus (HIV), anti-tuberculosis (TB), anti-Alzheimer or anti-cancer. The invention also discloses the method in synthesizing these compounds wherein the steps includes mixing curcumin, isatin derivatives or ninhydrin and proline in 20 mL methanol. The mixture was then refluxed with a solvent on a water bath and excess solvent was removed under vacuum. The residue subjected to flash column chromatography using petroleum ether: ethyl acetate mixture (4:1) as eluent to afford the product. The ratio for curcumin: isatin derivative/ninhydrin:proline is 1 :1 :2 and 1 :2:4.
A61K 31/407 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des systèmes hétérocycliques, p. ex. kétorolac, physostigmine
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
Accordingly, the invention discloses compounds of pyrrolothiazole moiety containing with mono bis substituted curcumin molecules which improves solubility of curcumin. The invention also discloses the method in synthesizing these compounds wherein the steps includes mixing curcumin, isatin derivatives or ninhydrin and thioproline (thiazolidine-4-carboxylic acid) in 20 mL methanol. The mixture was then refiuxed with a solvent on a water bath and excess solvent was removed under vacuum. The residue subjected to flash column chromatography using petroleum ether: ethyl acetate mixture (4:1) as eluent to afford the product. The ratio for curcumin: isatin derivative/ninhydrin:thioproline (thiazolidine-4-carboxylic acid) is 1:1:2 and 1:2:4.
A61K 31/41 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec plusieurs hétéro-atomes cycliques, l'un au moins étant l'azote, p. ex. tétrazole
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A cell culture apparatus (100) comprising a culture tank (110) for growing plant cell in a culture medium, having an upper portion (121) and a lower portion (122); a sterilizing means (107) encompassing the upper portion (121) of the culture tank (110) for sterilizing the culture tank (110); a cooling system (109) enclosing the lower portion (122) of the culture tank for stabilizing the temperature; a lighting means (106) fitted within the upper portion (121) of the culture tank (110) for providing the necessary light intensity and light colour to the cell culture; an aerating means (123) fitted within the lower portion (122) of the culture tank (110) for supplying air to the cell culture; and a covering means (120) having a plurality of openings for insertion of various applicators for providing predetermined growth conditions to the cell culture.
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
C12M 1/02 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'agitationAppareillage pour l'enzymologie ou la microbiologie avec des moyens d'échange de chaleur
C12M 1/04 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'introduction de gaz
73.
LANTHANUM CERIUM OXIDE THIN FILM AND ITS PREPARATION THEREOF
The present invention relates to a method of preparing lanthanum cerium oxide (La2Ce2O7) precursor using metal-organic decomposition method and transforming the precursor to a ternary lanthanum cerium oxide solid thin film with thickness range of 50 to 100 nm via post-deposition annealing in Argon ambient.
C01F 1/00 - Procédés de préparation des composés des métaux béryllium, magnésium, aluminium, calcium, strontium, baryum, radium, thorium ou des terres rares, en général
74.
A TOP DEAD SPARK TIMING DETECTION FOR DIRECT FUEL INJECTION TIMING 2 STROKE WASTE SPARK SYSTEM
The present invention generally relates to a means of detecting spark timing for direct fuel injection timing for a two stroke waste spark system. According to the present invention, a rotor (2) of an electrical generator is affixed to the end of a crankshaft. The said generator has stationary coils (1) mounted inside the said rotor (2) and wherein said rotor (2) houses at least two sets of magnets in a symmetric configuration. Each magnetic pole subtends just less than 90 degrees of rotation and wherein the said coils (1) are exposed to at least two sets of flux reversals per revolution at each end. Such configuration allows the engine to rotate the individual coils (1) in a sine-wave current with two cycles per revolution.
The present invention provides cutting insert for cutting machinery comprising a Zirconia Toughened Alumina (ZTA) having a nano metal oxide additive. A method method of fabricating cutting insert is also provided. The method comprises mixing alumina together with Yttria Stabilized Zirconia (YSZ) and nano metal oxide additives; compacting the mixture in a compaction mold of a desired shape; sintering the compacted mixture for a predetermined period; and machining the sintered mixture to form the cutting insert.
C04B 35/10 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base d'oxyde d'aluminium
B23B 27/14 - Outils de coupe sur lesquels les taillants ou éléments tranchants sont en matériaux particulier
C04B 35/63 - Préparation ou traitement des poudres individuellement ou par fournées utilisant des additifs spécialement adaptés à la formation des produits
76.
A CONFIGURABLE MULTI - MODULATION BASEBAND MODULATOR OF SOFTWARE DEFINED RADIO USING FPGA
The present invention relates to a configurable multi - modulation baseband modulator hereinafter referred as "MMBM" of software defined radio using FPGA. The present invention further relates to a means to extend single digital modulation. Single digital modulation of baseband modulator is extended to multiple digital amplitude and/or phase modulations that can be configured for various applications of software defined radio. The means comprise of modeling a configurable MMBM in digital signal processing basis, generating first hardware description language hereinafter referred as "HDL", designing second HDL, combining the first and second HDLs, synthesizing the combined HDL, implementing the synthesized HDL into FPGA, and measuring the results obtained in real time.
The present invention provides a dielectric resonator antenna for 5.8 GHz wireless communications. In one embodiment, the dielectric resonator antenna comprises a duroid substrate made from dielectric material, a microstrip line embedded in the substrate with slots, where the microstrip line is made from electrically conductive material, a SMA connector electrically coupled with one end of the microstrip line, and a plurality of dielectric resonators coupled with the microstrip line via the slots, wherein the microstrip line is configured in such a way that it goes through all the surface of the dielectric substrate so that the plurality of dielectric resonators form a condensed array format on the surface of the dielectric substrate, resulting a miniaturized dielectric resonator antenna. The present invention also provides a process for design and fabrication of the dielectric resonator antenna.
The present invention provides a dielectric resonator antenna for wireless communications, comprising a substrate made from electrically non-conductive material, a microstrip line embedded in the substrate, where the microstrip line is made from electrically conductive material, a RF connector electrically coupled with one end of the microstrip line, and a dielectric resonator element made from dielectric materials, where the dielectric resonator element is attached onto the microstrip line, wherein the microstrip line couples electromagnetic wave from the RF connector to the dielectric resonator element. The present invention further provides a process for design and fabrication of the dielectric resonator antenna.
The present invention provides a wideband dielectric resonator antenna for Ku- band applications. In one embodiment, the dielectric resonator antenna comprises a substrate made from electrically non-constructive material, a microstrip line embedded in the substrate, where the microstrip line is made from electrically conductive material, a RF connector electrically coupled with one end of the microstrip line, and two dielectric resonator elements disposed sequentially onto the microstrip line, forming a co-planar configuration. The present invention also provides a process for design and fabrication of the wideband dielectric resonator elements.
In the present invention, the skin from a processed fruit, such as rambutan, banana and jackfruit and a biodegradable plastic are blended as an industrial material to provide a biodegradable plastic product made from fruit skin in the form of powder that will return to the environment after disposal. A dry powder is created from the skin of rambutan, banana and jackfruit. A product is created from a raw material that is composed of 8 to 45% by weight of dry skin powder of rambutan, banana and jackfruit mixed with biodegradable plastic. Plastic additives, standard in the industry, can be added to achieve desired properties. For example, a plasticizer may be added in order to soften the biodegradable plastic by increasing its flexibility; polymerization modifiers such as cross-linkers may be added to enhance the properties of the base plastic, especially tensile properties; and a surfactant may be added to lower the surface tension of the liquid, allowing easier spreading and lowering interfacial tension between liquid and dried skin powder.
C08L 29/04 - Alcool polyvinyliqueHomopolymères ou copolymères d'esters partiellement hydrolysés d'alcools non saturés avec des acides carboxyliques saturés
C08L 101/06 - Compositions contenant des composés macromoléculaires non spécifiés caractérisées par la présence de groupes déterminés contenant des atomes d'oxygène
C08F 8/00 - Modification chimique par post-traitement
C08K 5/53 - Phosphore lié à l'oxygène lié uniquement à l'oxygène et au carbone
C08L 97/00 - Compositions contenant des matières contenant de la lignine
81.
SYSTEM OF AUTONOMOUS SURFACE VEHICLES WITH SWARMING ALGORITHM
A system and method for investigating the underwater topographic information of a water-body or water column that utilizes a plurality of autonomous surface vehicles ASVs (800) that implement a swarming search algorithm based on the biological behavior of the Drosophila (fruit fly) when in search for food or a mate and an algorithm based on the flight path of the Drosophila (fruit fly). The system of present invention comprises of a plurality of cylindrical shaped ASVs (800) that act swarming agents and are coordinated by a central base station (100) to search for a predefined target based on aforementioned algorithms.
G05D 1/12 - Commande pour la recherche d'un objectif
G06N 3/00 - Agencements informatiques fondés sur des modèles biologiques
G05B 13/00 - Systèmes de commande adaptatifs, c.-à-d. systèmes se réglant eux-mêmes automatiquement pour obtenir un rendement optimal suivant un critère prédéterminé
G06N 7/00 - Agencements informatiques fondés sur des modèles mathématiques spécifiques
82.
Method for preparing a gelling and viscosifying agent for drilling mud and the product thereof
A method for preparing lignin graft copolymer comprising: reacting lignocellulosic materials with an acrylic compound by bulk condensation under nitrogen atmosphere in the presence of a non-oxidizing strong organic acid as catalyst; separating the reaction mixture to obtain a solid phase mainly containing lignocellulosic materials and a liquid phase containing lignin graft copolymer and unreacted acrylic compound; and removing solvent from the liquid phase to obtain the lignin graft copolymer.
The present invention relates to a gate oxide, cerium oxide, with high dielectric constant (k) that is being integrated in a semiconductor and a method for producing metal-oxide-semiconductor device using the gate oxide with high dielectric constant (k). The gate oxide is being deposited on the semiconductor via post deposition annealing under 02 and N20 ambient. The semiconductor used in the present invention is Si-doped (n-type) Gallium nitride GaN epitaxial layer grown on sapphire substrate. The present invention firstly relates to a method for producing the oxide-semiconductor. The oxide- semiconductor is then subjected to an etching, evaporating and photolithography process to produce metal-oxide-semiconductor capacitor.
H01L 21/208 - Dépôt de matériaux semi-conducteurs sur un substrat, p. ex. croissance épitaxiale en utilisant un dépôt liquide
C23C 18/02 - Revêtement chimique par décomposition soit de composés liquides, soit de solutions des composés constituant le revêtement, ne laissant pas de produits de réaction du matériau de la surface dans le revêtementDépôt par contact par décomposition thermique
H01L 29/94 - Dispositifs à métal-isolant-semi-conducteur, p.ex. MOS
The invention relates to novel compounds which act has anti-mycobacterial properties, in particular anti-tuberculosis. The novel molecules of AM1, AM2, AM3, AM4, AM5, AM6, AM7, AM8, AM9, AM10, AM11, AM12, AM13, AM14, AM15, AS1, AS2, AS3, AS4, AS5, AS6, AS7, AS8, AS9, AS10, AS11, AS12, AS13 and AS14 are of substituted Mannich base and Schiff base which contains anti-tuberculosis properties. The invention presents the method for preparation of compounds AM1, AM2, AM3, AM4, AM5, AM6, AM7, AM8, AM9, AM10, AM11, AM12, AM13, AM14 and AM15, wherein the steps includes: (a) s synthesizing an aromatic ester derivative using an aromatic carboxylic acid and alcohol in the presence of concentrated sulfuric acid; (b) synthesizing an acid hydrazide derivative using the aromatic ester derivative from step (a); (c) synthesizing Schiff bases using the acid hydrazide derivative from step (b); and (d) synthesizing Mannich bases using the Schiff bases from step (c). The present invention presents the method for preparation of compounds AS1, AS2, AS3, AS4, AS5, AS6, AS7, AS8, AS9, AS10, AS11, AS12, AS13 and AS14, wherein the steps includes: (a) synthesizing an aromatic ester derivative using an aromatic carboxylic acid and alcohol in the presence of concentrated sulfuric acid; (b) synthesizing an acid hydrazide derivative using the aromatic ester derivative from step (a);and (c) synthesizing Mannich bases using the Schiff bases from step (b).
A61K 31/4709 - Quinoléines non condensées contenant d'autres hétérocycles
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
A61K 31/522 - Purines, p. ex. adénine ayant des groupes oxo liés directement à l'hétérocycle, p. ex. hypoxanthine, guanine, acyclovir
A61P 31/06 - Agents antibactériens pour le traitement de la tuberculose
C07D 401/04 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 401/14 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant au moins trois hétérocycles
C07D 473/18 - Composés hétérocycliques contenant des systèmes cycliques purine avec des atomes d'oxygène, de soufre ou d'azote liés directement en positions 2 et 6 un atome d'oxygène et un atome d'azote, p. ex. guanine
85.
NANOPOROUS ALUMINA AND PROCESS AND SYSTEM FOR PRODUCING THE SAME
An electrochemical system and process for producing nanoporous structures, said system comprising (among others) a power supply with a negative end and a positive end; a chamber for an electrolyte; two electrodes (one positive and one negative) immersed in said electrolyte; an electronic circuit board with an inlet and an outlet, said electronic circuit board comprising one or more power resistors, wherein the inlet is electrically coupled to the positive end. When the power supply is on, the one or more resistors of the electronic circuit board regulate the current within the chamber with different voltages to maintain the temperature of the electrolyte within the chamber at a certain level. The nanoporous structure (such as in particular nanoporous alumina) is produced on the positive electrode.
A metering device (100) of electricity utility equipped with capability of providing internet access comprises a first sensors (400) capable of real-time measuring utility data of a first recipient (500) and the utility data is acquired as analog signal; a processor (110) connected to the first sensors (400) via a signal processing unit, which process and convert the analog signal to digital signal, to obtain the measured utility data for analysis through instructions from one or more software applications; a hypervisor (120) coupled to the processor (1 10) allowing the processor (110) to host a first (126) and a second operating system (125) forming a first subnet and a second subnet thereon; and a communication module coupled to the processor (110) and adapted to provide internet access to the first recipient (500) via a first domain connected to the first subnet and send the utility data to a billing server via a second domain connected to the second subnet.
H04B 3/54 - Systèmes de transmission par lignes de réseau de distribution d'énergie
G01R 22/06 - Dispositions pour la mesure de l'intégrale dans le temps d'une puissance électrique ou d'un courant, p. ex. compteurs d'électricité par des méthodes électroniques
87.
A DISPOSABLE MULTIPLEX POLYMERASE CHAIN REACTION (PCR) CHIP AND DEVICE
A polymerase chain reaction (PCR) device including a chip assembly, a plurality of chambers being provided in said chip assembly adapted to hold samples, heating means wherein said chip assembly being located on said heating means whereby said chip assembly is allowed to operatively rotate on said heating means, a rotary wheel aiding said chip rotation and wherein said heating means comprises of plural temperature zones in a manner that on rotation of said chip means said sample chamber is shifted from one temperature zone to another by means of a rotary-linear motion system.
B01L 7/00 - Appareils de chauffage ou de refroidissementDispositifs d'isolation thermique
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
88.
AN APPARATUS AND METHOD FOR RAPID RATE OF TITANIUM DIOXIDE (TIO2) NANOTUBES ARRAYS FORMATION
The present invention is an apparatus and method for rapid rate of titanium dioxide (TiC>2) nanotube arrays formation. The apparatus (1) for producing titanium dioxide (TiO2) nanotube arrays comprises of an anodization chamber (2), an electrolyte solution (3) acting as an anodization medium, an anodization means characterized by a rectifier (4), an anionic electrode (5) and a cationic electrode (6), an effervescing tube (7) having a plurality of apertures for producing bubbles, a cooling means characterized by a pair of coolant channels having an inlet cooling channel (8) and an outlet cooling channel (9), and a plurality of interval connections (10) in between the inlet cooling channel (8) and outlet cooling channel (9), and an electrolyte circulating means having circulation channels and a pair of circulating channels. The method for producing titanium dioxide (TiO2) nanotube arrays comprises of preparing anionic electrode (5), preparing electrolyte solution (3), performing the anodization process at 25°C of around pH7 for 1 minute and collecting titanium dioxide (TiO2) nanotube arrays from the anionic electrode (5).
An apparatus of spot welding comprises a clamp structure having a hollow bottom arm (3) and a hollow upper arm (5), arranged in a tip to tip fashion, that a gap exists in between the opposing arms (3 and 5) for positioning of at least two layers of lapping metallic work pieces (1 and 2) and at least one of the opposing arms is moveable towards or away in relative to another for clamping or releasing the lapping metallic work pieces (1 and 2); a bottom conducting shaft (4) and upper conducting shaft (6) housed within the bottom arm (3) and the upper arm (5) respectively with the upper conducting shaft (6) capable of performing axial translational and/or rotational motions at its elongated central axis; and a controlling means (24) regulating the clamp structure and the opposing conducting shaft (4 and 6) as well as providing a user interface for management of the apparatus; wherein one of the tips of each opposing conducting shaft (4 and 6) contacting weld area (14) of the lapping metallic work pieces (1 and 2) under a predetermined pressure to conduct an electrical current thereto generating heat to soften the weld area of the metallic work pieces (1 and 2) without melting the metallic work pieces (1 and 2), and the upper conducting shaft (6) starts axial rotation to thrust into the weld area of the metallic work pieces (1 and 2) upon detecting of softening in the weld area; characterized in that a displacement sensor (12), in communication with the controlling means (24), is used in conjunction with the conducting shafts (4 and 6) to detect slight axial movement of at least one conducting shaft towards the weld area to determine softening of the weld area and initiates the upper conducting shaft (6) to rotate.
B23K 20/12 - Soudage non électrique par percussion ou par une autre forme de pression, avec ou sans chauffage, p. ex. revêtement ou placage la chaleur étant produite par frictionSoudage par friction
B23K 31/02 - Procédés relevant de la présente sous-classe, spécialement adaptés à des objets ou des buts particuliers, mais non couverts par un seul des groupes principaux relatifs au brasage ou au soudage
The present invention relates to an improved mechanical mating interface apparatus for reconfigurable machine tools. The improved mechanical mating interface (80a and 80b) includes: (a) a male coupling means (81) having an island region (82a) protruded from a trough region (82b) of a male interface plate (80a) and a land surface region (82c); (b) a female coupling means (83) having a countersunk region (84a) with protruded lip (84b) constructed from a land surface region (84c) of a female interface plate (80b); (c) a dowel (86) is associated with a slot (88) provided at the male- and female-interface plates (80a, 80b); wherein the male- and female- coupling means (81, 83) are matingly engageable to each other and enable to provide self-concentric and self-align features in reconfigurable environment.
The present invention relates to a method in rapid serodiagnosis of the disease melioidosis by using a modified method for an acidified glycine extraction of the cell surface proteins (CSP) antigen of Burkholderia pseudomallei and the use of the extracted cell surface proteins (CSP) to develop a rapid and simple modified dot enzyme immunoassay (dotEIA) test. Accordingly, a method for serodiagnosis of melioidosis in a patient, the method comprises steps of (a) preparing a medium for growing Burkholderia pseudomallei; (b) growing the Burkholderia pseudomallei in broth; (c) harvesting the Burkholderia pseudomallei from step (ii) by centrifugation; (d) extracting Burkholderia pseudomallei cell surface proteins (CSP) from step (iii) by acidified glycine extraction method; (e) standardizing and optimizing the CSP antigens from step (iv) and enzyme conjugates reagents to develop a dot enzyme immunoassay; (f) designing assay protocol for dot enzyme immunoassay (dot EIA) based on the concentrations obtained from standardization assay in step (v); (g) preparing serum / plasma from blood specimen obtained from a patient; and (h) detecting antibody isotypes in serum/plasma from patient against the Burkholderia pseudomallei CSP antigens using the dot enzyme immunoassay (dot EIA) from step (vi)and serum/plasma from patient from step (vii). Results from the test can be determined by visible observation of the reaction. This method of diagnosis allows simultaneous detection of serum immunoglobulin G (IgG), immunoglobulin M (IgM) and immunoglobulin A (IgA) antibody isotypes for serodiagnosis of melioidosis. Also provided is a kit for serodiagnosis of melioidosis wherein the kit includes (a) test strips dotted with optimized concentration of cell surface protein (CSP); (b) anti-human immunoglobulin G (IgG), immunoglobulin M (IgM) and immunoglobulin A (IgA); (c) nitroblue tetrazolium (solution A); (d) C 1 -5 bromo-4-chloro-3-indolylphosphate p-toluidine salt (solution B); (e) phosphate buffered saline buffer at pH 9.6 (substrate buffer); (f) 20 mM tris buffered saline at pH 7.4; (g) controls for reaction determination; and (f) reaction tray.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
92.
A POWER METERING SYSTEM AND A METHOD OF DISPLAYING READING DERIVED FROM THE SAME
A metering apparatus installed to a distribution network of a consumable commodity comprises a plurality of sensors capable of real-time measuring consumption data of the consumable commodity used by a plurality of recipients located in a single building that each sensor is responsible for measuring consumption rate of one recipient of the consumable commodity and the measurement is acquired as analog signal; a processor; a storage device; a display unit, accessible by more than one user of the recipients allowing the user to acquire information of the analysis; and an input means receiving input from the user; wherein the instructions of One or more software applications are used for consumption data recording, signal processing, automated metering, theft detection, demand management or any combination thereof and the common display is able to simultaneously show analysis information and/or reading of the automated metering of at least two recipients.
G08C 15/06 - Dispositions caractérisées par l'utilisation du multiplexage pour la transmission de plusieurs signaux par une voie commune successivement, c.-à-d. utilisant la division de temps
93.
USES OF BIOLOGICAL COMPOUNDS FROM TOXOPLASMA SP AND RELATED COMPOUNDS
The present invention relates to a plurality of biological compounds, derived from Toxoplasma sp. There is provided a method for detecting substances produced by or present in Toxoplasma sp., or substances produced by or present in a human or animal body in response to Toxoplasma sp. infection. In particular the present invention uses excretory- secretory proteins produced by Toxoplasma sp. as a biomarker of infection. The present invention also provides for the use of these biological compounds in a medicament for management or prophylaxis of Toxoplasma sp. infection or a disease resulting therefrom, as well as their use in the manufacture of a product for diagnosis, management or prophylaxis of Toxoplasma sp. infection or a disease resulting therefrom.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
94.
SILICON NANOWIRE TRANSISTOR (SINWT) AND PROCESS FOR FABRICATING THE SAME
The present invention provides a silicon nanowire transistor fabricated on a silicon-on-insulator (SOI) wafer, comprising a source pad, a drain pad, a lateral gate pad, and a silicon nanowire as channel. The present invention further provides a process for fabricating the silicon nanowire transistor, where the process comprises patterning by local anodic oxidation using atomic force microscopy (AFM) nanolithography to form a nanoscale oxide pattern corresponding to the components of the silicon nanowire transistor on top of the substrate; etching the substrate with a basic, anisotropic chemical etchant to remove the portions of the substrate that are not covered by the nanoscale oxide pattern; and further etching the substrate with an acidic, isotropic chemical etchant to remove the nanoscale oxide pattern.
H01L 21/336 - Transistors à effet de champ à grille isolée
B82B 1/00 - Nanostructures formées par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
H01L 29/775 - Transistors à effet de champ avec un canal à gaz de porteurs de charge à une dimension, p.ex. FET à fil quantique
H01L 29/78 - Transistors à effet de champ l'effet de champ étant produit par une porte isolée
95.
A PROCESS FOR PRODUCING SILICON CARBIDE (SIC) NANOWIRES ON A SILICON SUBSTRATE
This invention relates to a process for producing a large amount of silicon carbide (SiC) nanowires (20) on a silicon wafer (10) through direct reaction between silicon and carbon sources without the use of any metallic catalyst and with advantage of direct integration of nanowires onto the silicon (Si) substrate, which enables device fabrication. Said process includes placing a silicon substrate (10) and a crucible (14) filled with 0.5g to 1.0g of carbon powder (12) into a furnace (18); creating a vacuum in the furnace (18) between 20 to 40 mTorr; introducing argon gas into the furnace (18); heating the furnace (18) to a reaction temperature between 1200 °C and 1350 °C; and cooling the furnace (18) to room temperature.
B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
H01L 21/20 - Dépôt de matériaux semi-conducteurs sur un substrat, p. ex. croissance épitaxiale
B82B 1/00 - Nanostructures formées par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
The present invention discloses a high-strength and biocompatible calcium phosphate composite material that is suitable for use as bone implants or repairs. Accordingly, the calcium phosphate composite of the present invention, which may be used as an injectable bone replacing material, comprises at least one calcium phosphate reinforced with a protein concentrate and carbon nanotubes to produce a high compressive strength composite or cement.
A61L 27/40 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent
A61L 27/42 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice inorganique
97.
CERAMIC COMPOSITION, LOW VOLTAGE ZINC OXIDE VARISTOR MADE FROM THE CERAMIC COMPOSITION AND PROCESS FOR MANUFACTURING THE LOW VOLTAGE ZINC OXIDE VARISTOR
The present invention provides a ceramic composition for manufacturing a low voltage zinc oxide varistors. The present invention further provides a low voltage zinc oxide varistor. The present invention also provides a process for manufacturing the low voltage zinc oxide varistor. Superior energy handling capabilities are demonstrated by the low voltage varistors in that the varistors are capable of handling very high surge peak currents over twice the peak current specified by international standards.
C04B 35/453 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base d'oxydes de zinc, d'étain ou de bismuth ou de leurs solutions solides avec d'autres oxydes, p. ex. zincates, stannates ou bismuthates
H01C 7/112 - Noyaux de varistance en oxyde métallique du type ZnO
H01C 7/10 - Résistances fixes constituées par une ou plusieurs couches ou revêtementsRésistances fixes constituées de matériaux conducteurs en poudre ou de matériaux semi-conducteurs en poudre avec ou sans matériaux isolants sensibles à la tension, p. ex. varistances
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/7028 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques
An RFID reader system (100) with a wireless communication module (103, 203) is provided, the system (100) includes an RFID tag (200) which further includes a microcontroller (102, 202) coupled to the wireless communication module (103, 203) in the RFID reader system (100) and the RFID tag (200), a motion sensor (204) coupled to the microcontroller (102, 202) in the RFID tag (200), wherein the wireless communication module (103) is coupled to an antenna (108) in the RFID system (100) and the RFID tag (200) to transmit and receive data within the RFID reader system (100) and RFID tag (200).
H04Q 5/22 - Dispositifs de sélection dans lesquels plusieurs postes d’abonnés sont connectés par la même ligne au central avec connexion indirecte, c.-à-d. à travers un centre de commutation subordonné le centre subordonné ne permettant pas une interconnexion d'abonnés reliés à ce centre
G08B 13/14 - Déclenchement mécanique par l'enlèvement ou les essais de déplacement d'articles portatifs
A communication translation system between at least one RSW based client (101 )and at least one SIP EP (103) is provided, the system (100)includes at least one RSW based client (101 ), an RSW based server (102), at least one SIP EP (103), and a translation server (104) which further includes a login admission control module, a registration module, a session initiation module, a module for forwarding media, a module for forwarding conference setup and a plurality of control messages. This system can operate in two configurations; one configuration is without the assistance of the SIP server as seen in Figure 1 whilst the other configuration includes an SIP server.
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