A method of forming a photovoltaic device (6) comprising a plurality of electrically interconnected back-contact photovoltaic cell pieces (13) comprises: i) obtaining a back-contact photovoltaic cell (1) comprising an array of sections (10) logically organised in rows and columns, each section (10) comprising, at a backside (11) of the cell (1), at least one first contact (21) of a first polarity and at least one second contact (22) of a second polarity, opposite to the first polarity, ii) attaching, to said backside (11), a cell-level interconnection sheet (3) comprising: an insulating carrier sheet (30), and a plurality of conductive wires (31, 32), comprising parallel interconnects (31), and serial interconnects (32), and iii) partitioning the photovoltaic cell (1) into a plurality of physically separated cell pieces (13), wherein said attaching and said partitioning are performed so that the cell pieces (13) in each row are connected in parallel by the parallel interconnects (31), and the cell pieces (13) in each column are interconnected in series by the serial interconnects (32).
A bypass diode assembly and a method for fabricating the bypass diode assembly are provided, the bypass diode assembly comprising an electrically insulating tape, an electrically conductive ribbon extending over the back side of the tape and locally exposed at the front side of the tape through an opening, a semiconductor component positioned in a hole through the tape, wherein the semiconductor component comprises a diode electrically connected between a first contact pad of the semiconductor component in electrical contact with the electrically conductive ribbon and a second contact pad of the semiconductor component, and an electrically conductive ribbon portion on the front side of the tape in electrical contact with the second contact pad of the semiconductor component. The electrically conductive ribbon portion is electrically isolated from the first electrically conductive ribbon by the electrically insulating tape. A photovoltaic module comprising at least one bypass diode assembly is provided.
H10F 19/70 - Dispositifs intégrés, ou ensembles de plusieurs dispositifs, comprenant au moins une cellule photovoltaïque couverte par le groupe , p. ex. modules photovoltaïques comportant des diodes de dérivation
H10D 80/20 - Ensembles de plusieurs dispositifs comprenant au moins un dispositif couvert par la présente sous-classe l’au moins un dispositif étant couvert par les groupes , p. ex des ensembles comprenant des condensateurs, des transistors FET de puissance ou des diodes Schottky
H10F 19/90 - Structures pour la connexion des cellules photovoltaïques, p. ex. interconnexions ou espaceurs isolants
The invention relates to method for developing and growing tooth organoids comprising the steps of, dissociating tooth tissue comprising dental epithelial stem cells, seeding the dissociated cells in a scaffold mimicking an extracellular matrix; and growing and passaging the cells in a medium suitable for organoid growth, wherein the medium does not comprise epidermal growth factor (EGF), thereby obtaining and expanding organoids.
The present invention relates to the study of stochastic systems and, more specifically, to systems and methods to quantify the transition rates in stochastic systems having a plurality of states. An aspect of the invention relates to a method for quantifying a plurality of transition rates of a stochastic system that can be in a plurality of states, comprising the steps of: providing the stochastic system; generating an equivalent electric circuit that represents a probability current associated with the state transitions in the stochastic system; applying a periodic perturbation P to the stochastic system, having a driving frequency ω that is varied within a predetermined frequency range; measuring an impedance response of the stochastic system to the periodic perturbation, including at least an amplitude and a phase shift as functions of the driving frequency ω; mapping the values of the electrical component of the equivalent electric circuit such that its impedance Z matches the frequency-dependence of the amplitude and phase shift in the measured impedance response; and, quantifying the transition rates of the stochastic system based on the equivalent electric circuit.
An assembly for electrically contacting and connecting photovoltaic cells, is provided, comprising first and second electrically insulating foils laterally shifted in a first direction. The assembly comprises a plurality of electrically conductive wires arranged substantially parallel to each other and substantially extending over both electrically insulating foils in the first direction, wherein the plurality of electrically conductive wires is arranged on a first foil surface of the first electrically insulating foil and further on a second foil surface of the second electrically insulating foil, being located at opposite sides of the assembly. The plurality of electrically conductive wires is locally attached to both electrically insulating foils without penetrating therethrough. A method for fabricating the assembly is provided.
A photovoltaic module includes at least one string of solar cells wherein the solar cells are electrically connected in series using a plurality of connecting elements, wherein each connecting element electrically connects a frontside of one of the solar cells of the at least one string with a backside of the neighboring solar cell of the at least one string; a weave of electrically insulating yarns on which the solar cells are positioned; at least one electronic device comprising a first terminal, and a second terminal, wherein the at least one electronic device is fixed to the weave and wherein the first terminal, and the second terminal are respectively electrically connected with the connecting elements at the backsides of neighboring solar cells of the at least one string.
H01L 31/0443 - Modules PV ou matrices de cellules PV individuelles comprenant des diodes de dérivation comportant des diodes de dérivation intégrées ou directement associées aux dispositifs, p.ex. diodes de dérivation intégrées ou formées dans ou sur le même substrat que les cellules PV
H01L 31/05 - Moyens d’interconnexion électrique entre les cellules PV à l’intérieur du module PV, p.ex. connexion en série de cellules PV
7.
COMPUTER-IMPLEMENTED METHOD TO PREDICT INDIVIDUAL REFERENCE CHANGE VALUES
A computer-implemented non-parametric method for estimating the upper and lower bounds of an Individual Reference Change Value, I-RCV, for a measured test value of a subject, said method using a longitudinal data set of corresponding test values for said subject and at least three different independent subjects, and applying two I-RCV models on said longitudinal data to estimate said upper and lower bounds with a symmetry property between said upper and lower bounds, characterized in that the two I-RCV models include the observed time lags between consecutive measurements in the longitudinal data as a covariate in the model to determine a difference between the two consecutive measurements on the same subject.
G06F 17/18 - Opérations mathématiques complexes pour l'évaluation de données statistiques
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
8.
METHOD AND ASSEMBLY FOR EVALUATING AN EGGSHELL TEMPERATURE
A method and a sensor assembly for measuring and evaluating an egg-shell temperature, in particular of poultry eggs in a hatching environment, wherein the method comprises the steps of providing a sensor in direct contact with an egg, the sensor being configured to non-invasively measure a temperature of an eggshell of said egg, and the sensor measuring said eggshell temperature.
G01K 1/143 - SupportsDispositifs de fixationDispositions pour le montage de thermomètres en des endroits particuliers pour la mesure de la température de surfaces
A system (100) for determining contact with an object (102) or a fluid (108) comprises: a sensor (110) comprising an electrically conductive structure (112), wherein the sensor (110) is configured to induce a current through the electrically conductive structure (112) and sense a temperature- induced change in resistance of the electrically conductive structure (112) for determining contact information, wherein the temperature-induced change in resistance is dependent on heat exchange with the electrically conductive structure (112) and an environment; a processor unit (120) configured to receive the sensed temperature-induced change in resistance and being configured to process the sensed temperature-induced change in resistance for determining contact information between the sensor (110) and the object (102) or the fluid (108).
G01K 7/18 - Mesure de la température basée sur l'utilisation d'éléments électriques ou magnétiques directement sensibles à la chaleur utilisant des éléments résistifs l'élément étant une résistance linéaire, p. ex. un thermomètre à résistance de platine
G01F 23/24 - Indication ou mesure du niveau des liquides ou des matériaux solides fluents, p. ex. indication en fonction du volume ou indication au moyen d'un signal d'alarme en mesurant des variables physiques autres que les dimensions linéaires, la pression ou le poids, selon le niveau à mesurer, p. ex. par la différence de transfert de chaleur de vapeur ou d'eau en mesurant les variations de résistance de résistances électriques produites par contact avec des fluides conducteurs
10.
METHOD AND MEANS FOR PREDICTION AND EVALUATION OF THERAPY RESPONSE IN RHEUMATOID ARTHRITIS
The application discloses methods for predicting the response of a subject diagnosed with rheumatoid arthritis to treatment with an anti-rheumatic drug or for evaluating the response of subject diagnosed with rheumatoid arthritis to treatment with an anti-rheumatic drug. Said methods include detecting antibodies against one or more peptides, antibody-binding fragments, variants or immune reactive peptides thereof in a sample of the subject. Also provided are peptides, antibody-binding fragments, variants or immune reactive peptides, compositions comprising said peptides, antibody-binding fragments, variants or immune reactive peptides thereof and the use of peptides, antibody-binding fragments, variants or immune reactive peptides thereof and compositions.
G01N 33/564 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour complexes immunologiques préexistants ou maladies auto-immunes
11.
METHOD FOR DETERMINING A TOXICITY AND/OR GROWTH PROMOTION EFFECT OF A TREATMENT OR COMPOUND
The present invention relates to the field of screening methods. More specifically, the present invention pertains to a method for determining a toxicity and/or growth promotion effect of any one of a treatment or compound, and a computer program comprising instructions to carry out steps of said method.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
12.
COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR USE IN NEURODEGENERATIVE DISORDERS
The present invention relates to compounds, pharmaceutical compositions and medicaments suitable for use in the prevention and/or treatment of neurodegenerative disorders, such as for example demyelinating diseases. These compounds have been found to improve cognition and/or neuroplasticity as well as to induce and/or stimulate remyelination of the myelin sheet. Furthermore, the present invention relates to methods for synthesis of said compounds.
C07D 231/12 - Composés hétérocycliques contenant des cycles diazole-1, 2 ou diazole-1, 2 hydrogéné non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle
A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
C07C 45/64 - Préparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogènePréparation des chélates de ces composés par des réactions ne créant pas de groupe C=O par introduction de groupes fonctionnels contenant de l'oxygène lié uniquement par liaison simple
C07D 261/08 - Composés hétérocycliques contenant des cycles oxazole-1, 2 ou oxazole-1, 2 hydrogéné non condensés avec d'autres cycles comportant plusieurs liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle
C07D 405/06 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
C07D 413/06 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
13.
MAINTAINING REGULATORY T CELL (Treg) FUNCTIONALITY UNDER CONDITIONS TRIGGERING Treg DYSFUNCTIONALITY
MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (Allemagne)
Inventeur(s)
Kleinewietfeld, Markus
Hamad, Ibrahim
Côrte-Real, Beatriz
Mueller, Dominik N.
Abrégé
The invention relates to protecting regulatory T cells (Tregs) against dysfunctionality as caused in e.g. the auto-immune disease setting. In particular, such protection is warranted in case of adoptive transfer or Tregs as a means of treatment of auto-immune and other diseases, and as a means of controlling transplant or graft rejection. Furthermore in particular, the protection is enabled by inhibiting the Treg mitochondrial sodium/lithium/calcium exchanger.
The present invention concerns polymer electrolytes comprising a polymer backbone derived from dialkylacrylamide monomers which effectively encapsulate deep eutectic solvents (DES) and are compatible with high potential electrodes. The present invention further concerns composite cathodes and electrochemical cells comprising the polymer electrolyte, and uses thereof.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
H01M 10/0565 - Matériaux polymères, p. ex. du type gel ou du type solide
15.
POLYMER ELECTROLYTE COMPRISING A POLYACRYLAMIDE AND METHODS FOR THE PRODUCTION THEREOF
The present invention concerns polymer electrolytes comprising a polymer backbone derived from acrylamide monomers and bis-acrylamide crosslinkers which effectively encapsulate deep eutectic solvents (DES) and are compatible with high potential electrodes. The present invention further concerns composite cathodes and electrochemical cells comprising the polymer electrolyte, and uses thereof.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
H01M 10/0565 - Matériaux polymères, p. ex. du type gel ou du type solide
Example embodiments relate to methods for continuous photovoltaic cell stringing and photovoltaic cell assemblies. An example method includes providing a foil in a provision direction in a continuous manner. The method also includes cutting at least one slit into the foil along the provision direction. Additionally, the method includes creating at least one slit opening by folding open the foil at a location of the at least one slit. Further, the method includes providing at least one electrically conductive wire near a first surface of the foil along the provision direction aligned with the at least one slit opening in a continuous manner. Yet further, the method includes folding back the foil at the at least one slit opening after the electrically conductive wire provision such that the at least one electrically conductive wire changes its position.
H01L 31/20 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives - les dispositifs ou leurs parties constitutives comprenant un matériau semi-conducteur amorphe
H01L 31/18 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
H01L 31/05 - Moyens d’interconnexion électrique entre les cellules PV à l’intérieur du module PV, p.ex. connexion en série de cellules PV
H10K 30/57 - Dispositifs photovoltaïques [PV] comprenant des jonctions multiples, p. ex. des cellules PV en tandem
H10K 71/60 - Formation de régions ou de couches conductrices, p. ex. d’électrodes
The present invention is directed to selective detection of monomeric C-reactive protein (CRP) in a body fluid sample. In particular, the present invention provides the use of a DNA aptamer for the detection of monomeric CRP in an isolated sample of body fluid from a subject. The invention also provides DNA aptamers that specifically bind to monomeric CRP. Finally, also a detection method for monomeric CRP in a body fluid sample using a DNA aptamer and a kit for the detection of monomeric CRP in a body fluid sample are described.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
C12N 15/115 - Aptamères, c.-à-d. acides nucléiques liant spécifiquement une molécule cible avec une haute affinité sans s'y hybrider
A solution for forming a solid electrolyte (5), the solution comprising: a plurality of silicon oxide particles (1) dissolved in a liquid medium, the silicon oxide particles (1) being functionalized with organic moieties (2) comprising: at least four non-hydrogen atoms, of which one atom is covalently bonded to a silicon atom of the silicon oxide particles, and a linkable functional group (21) capable, after activation by a radical species, of forming a covalent bond by reaction with another identical linkable functional group, wherein the organic moiety (2) comprises at least two atoms, not part of the linkable functional group (21), that are bonded by a n bond to each other, wherein a ratio of the number of said organic moieties (2) to the number of silicon atoms comprised in the plurality of silicon oxide particles (1) is at least 0.3, and an electrolyte compound (52).
The present disclosure related to a method for interconnecting photovoltaic cells in order to form a photovoltaic cells assembly is provided. The method comprises the steps of providing a first photovoltaic cell comprising a first surface, a second surface, a first edge, and a second edge, arranging a conductive wire on the first surface of the first photovoltaic cell according to a certain pattern, and attaching the conductive wire to the first surface of the first photovoltaic cell with the aid of a first non-conductive yarn by stitching in the area of the first edge of the first photovoltaic cell according to a first stitch type.
The invention relates to method for developing and growing tooth organoids comprising the steps of, dissociating tooth tissue comprising dental epithelial stem cells, seeding the dissociated cells in a scaffold mimicking an extracellular matrix;and growing and passaging the cells in a medium suitable for organoid growth, wherein the medium does not comprise epidermal growth factor (EGF), thereby obtaining and expanding organoids.
H01G 9/00 - Condensateurs électrolytiques, redresseurs électrolytiques, détecteurs électrolytiques, dispositifs de commutation électrolytiques, dispositifs électrolytiques photosensibles ou sensibles à la températureProcédés pour leur fabrication
H10K 30/30 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant des hétérojonctions de masse, p. ex. des réseaux interpénétrés de domaines de matériaux donneurs et accepteurs
H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
H10K 71/16 - Dépôt d'une matière active organique en utilisant un dépôt physique en phase vapeur [PVD], p. ex. un dépôt sous vide ou une pulvérisation cathodique
A sensor device for measuring a temperature in a photovoltaic laminate structure and a sensor system comprising such a sensor device is provided. The sensor device includes a capillary for being embedded in the laminate structure between two layers thereof, a medium arranged within the capillary, and an optical fiber extending through the capillary and surrounded by the medium. At least a portion of the optical fiber has temperature-dependent transmission characteristics.
G01K 11/3206 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou utilisant des changements dans la transmittance, la diffusion ou la luminescence dans les fibres optiques en des endroits distincts de la fibre, p. ex. utilisant la diffusion de Bragg
G01B 5/00 - Dispositions pour la mesure caractérisées par l'utilisation de techniques mécaniques
G01D 5/353 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensibleMoyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminéTransducteurs non spécialement adaptés à une variable particulière utilisant des moyens optiques, c.-à-d. utilisant de la lumière infrarouge, visible ou ultraviolette avec atténuation ou obturation complète ou partielle des rayons lumineux les rayons lumineux étant détectés par des cellules photo-électriques en modifiant les caractéristiques de transmission d'une fibre optique
G01L 1/24 - Mesure des forces ou des contraintes, en général en mesurant les variations des propriétés optiques du matériau quand il est soumis à une contrainte, p. ex. par l'analyse des contraintes par photo-élasticité
H02S 50/15 - Tests de dispositifs PV, p. ex. de modules PV ou de cellules PV individuelles utilisant des moyens optiques, e.g. utilisant l'électroluminescence
24.
Method and an apparatus for applying thin film material onto a substrate
A method for applying thin film material onto a substrate comprises: forming microdroplets of a solvent and a solute material forming the thin film material; depositing the microdroplets on an upper surface of a micro-structured mesh, wherein the microdroplets are deposited to allow coalescing into droplets extending into the micro-structured mesh; and arranging a surface of the substrate in close relation to a bottom surface of the micro-structured mesh such that a capillary force draws liquid of the droplets onto the surface of the substrate, whereby forced dynamic wetting of the surface of the substrate is provided to form a liquid film on the surface of the substrate.
B05B 17/06 - Appareils de pulvérisation ou d'atomisation de liquides ou d'autres matériaux fluides, non couverts par les autres groupes de la présente sous-classe opérant suivant des procédés particuliers utilisant des vibrations ultrasonores
B05D 1/02 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces réalisés par pulvérisation
37 - Services de construction; extraction minière; installation et réparation
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Construction services; Building maintenance and repair; Servicing and fix in relation to the following goods: Timber-frame structures; Installation of fittings for buildings; Building, construction and demolition; Construction consultancy; Construction information; Building construction supervision services for building projects; Consultancy, awareness-raising and information regarding the aforesaid services, including provided via electronic networks such as the Internet. Science and technology services; Industrial analysis and research services; Construction drafting; Construction drafting; Civil engineering planning services; Design services for architecture; Quality control and authentication; IT services; Software development, programming and implementation; Design and development of computer software for process control; Design and development of computer software for evaluation and calculation of data; draughting and Development relating to the following goods: Software for checking the racking resistance of timber frames; Consultancy, information and awareness-raising regarding the aforesaid services, including provided via electronic networks such as the Internet.
26.
Interconnect, an electronic assembly and a method for manufacturing an electronic assembly
An interconnect for connecting a first electronic circuit to a second, external stretchable electronic circuit device comprises: conductive lines of the first electronic circuit arranged in a plane; connectors configured to define an overlap in the plane between each end of the conductive lines with a corresponding end of stretchable conductive lines providing an electrical connection between the conductive lines and the stretchable conductive lines over the entire overlap; and at least one anchoring structure for providing an anchoring of the first electronic circuit with the second, external stretchable electronic circuit device, wherein the at least one anchoring structure provides anchoring transverse to the plane in anchoring positions on opposite sides of the overlap.
H01R 12/79 - Dispositifs de couplage pour circuits imprimés flexibles, câbles plats ou à rubans ou structures similaires se raccordant à des circuits imprimés rigides ou à des structures similaires
H05K 1/03 - Emploi de matériaux pour réaliser le substrat
H05K 1/14 - Association structurale de plusieurs circuits imprimés
H05K 3/32 - Connexions électriques des composants électriques ou des fils à des circuits imprimés
27.
GAS-FILLED MICROBUBBLE AND METHOD FOR FABRICATING A GAS-FILLED MICROBUBBLE
The disclosure relates to a gas-filled microbubble, comprising: a shell encapsulating a gas volume; wherein the shell comprises a gas impermeable molecular layer; wherein the shell is functionalized with a plurality of polymerizable molecules, wherein the polymerizable molecules comprise pentacosadienoic acid, PCDA, derivatives, in particular polyethylene glycol PCDA, PCDA-PEG; wherein the polymerizable molecules are configured to undergo polymerization when being irradiated with UV radiation in a determined wavelength range; and wherein the polymerization of the polymerizable molecules changes physicochemical properties, such as viscoelastic properties, of the microbubble.
The present invention in general relates to the field of antibody profiling in spondyloarthritis. In particular, the inventors found that antibody levels against selected peptides are raised in spondyloarthritis patients, and herein provide a diagnostic method and kit comprising such peptides for use in the diagnosis of spondyloarthritis.
G01N 33/564 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour complexes immunologiques préexistants ou maladies auto-immunes
29.
COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR USE IN NEURODEGENERATIVE DISORDERS
The present invention relates to compounds, pharmaceutical compositions and medicaments suitable for use in the prevention and/or treatment of neurodegenerative disorders, such as for example demyelinating diseases. These compounds have been found to improve cognition and/or neuroplasticity as well as to induce and/or stimulate remyelination of the myelin sheet. Furthermore, the present invention relates to methods for synthesis of said compounds.
C07D 295/08 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de carbone du cycle avec des radicaux hydrocarbonés substitués liés aux atomes d'azote du cycle substitués par des atomes d'oxygène ou de soufre liés par des liaisons simples
A61K 31/4155 - 1,2-Diazoles non condensés et contenant d'autres hétérocycles
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
C07D 261/08 - Composés hétérocycliques contenant des cycles oxazole-1, 2 ou oxazole-1, 2 hydrogéné non condensés avec d'autres cycles comportant plusieurs liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle
C07D 413/06 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
30.
METAL ORGANIC FRAMEWORK PHOTONIC AND ELECTRONIC DEVICE FOR GAS SENSING
The invention relates to gas sensors comprising subsequently arranged from bottomto top: a bottom first layer (1) of a reflective or semi-reflective conductive materialor a bottom first layer (1) which is a distributed Bragg reflector; a second layer (2) with a thickness between 10 and 500 nm, of a material which is transparent or semi-transparent to ultra-violet, visible, or/and near-infrared light, wherein optionally the order of layer (1) and (2) is switched; a third layer (3) of a porous sensing material specifically binding a volatile analyte; an optional fourth layer (4) of an organic polymer, a metal-oxide film or a hybrid organic-inorganic film with a maximum one-side roughness of 20 nm and thickness between 0 and 100 nm, and a top fifth layer (5) of a gas permeable, semi-reflective, and conductive material.
G01N 21/3504 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge pour l'analyse des gaz, p. ex. analyse de mélanges de gaz
G01N 21/45 - RéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique en utilisant des méthodes interférométriquesRéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique en utilisant les méthodes de Schlieren
G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur
G01N 27/22 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la capacité
G01N 21/77 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique
31.
METHOD AND MEANS FOR DIAGNOSIS OF SPONDYLOARTHRITIS
The present invention in general relates to the field of antibody profiling in spondyloarthritis. In particular, the inventors found that antibody levels against selected peptides are raised in spondylarthritis patients, and herein provide a diagnostic method and kit comprising such peptides for use in the diagnosis of spondyloarthritis.
G01N 33/564 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour complexes immunologiques préexistants ou maladies auto-immunes
32.
SPOREBIOTICS FOR THE PREVENTION AND/OR TREATMENT OF IL-17 RELATED DISORDERS
The invention in general relates to the use of probiotics for the management of IL-17 related disorders. More specifically, the present invention relates to the use of Bacillus coagulans or Bacillus subtilis; in particular spore-forming probiotics. or a combination of both strains for the prevention or treatment of IL-17 related disorders, for example neurodegenerative disorders such as multiple sclerosis, Parkinson's disease, Alzheimer disease or Amyotrophic Lateral Sclerosis (ALS). The present invention also discloses the use of Bacillus coagulans or Bacillus subtilis or a combination of both strains as alternative therapy or adjunct therapy for IL-17 suppression treatment.
A61K 35/00 - Préparations médicinales contenant des substances ou leurs produits de réaction de constitution non déterminée
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
The present invention is directed to a device for measurement of the rigidity and/or tumescence of a penis during a penile tumescent event. In particular, the device of the present invention comprises axial and/or radial monitoring means for monitoring the axial and/or radial tumescence and/or rigidity of a penis during a penile tumescent event. The present invention further also provides methods for monitoring the axial and/or radial tumescence and rigidity of a penis.
The present invention relates to the field of screening methods. More specifically, the present invention pertains to a method for determining a toxicity and/or growth promotion effect of any one of a treatment or compound, and a computer program comprising instructions to carry out steps of said method.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
A01H 1/00 - Procédés de modification des génotypes
35.
PHLORETIN FOR USE IN THE TREATMENT OF NEURODEGENERATIVE AND DEMYELINATING DISEASES
The present application is related to compositions comprising phloretin and/or a derivative thereof for use in the treatment and/or prevention of a neurodegenerative disease, more specifically a neurodegenerative and demyelinating disease. Further, the use of phloretin and/or a derivative thereof in in vitro, ex vivo and in vivo assays is disclosed.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
The present invention is directed to selective detection of monomeric C-reactive protein (CRP) in a body fluid sample. In particular, the present invention provides the use of a DNA aptamer for the detection of monomeric CRP in an isolated sample of body fluid from a subject. The invention also provides DNA aptamers that specifically bind to monomeric CRP. Finally, also a detection method for monomeric CRP in a body fluid sample using a DNA aptamer and a kit for the detection of monomeric CRP in a body fluid sample are described.
C12N 15/115 - Aptamères, c.-à-d. acides nucléiques liant spécifiquement une molécule cible avec une haute affinité sans s'y hybrider
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
38.
METHOD FOR INTERCONNECTING PHOTOVOLTAIC CELLS AND PHOTOVOLTAIC CELLS ASSEMBLY BEING PRODUCIBLE THEREBY
A method for interconnecting photovoltaic cells in order to form a photovoltaic cells assembly is provided. Said method comprises the steps of providing a first photovoltaic cell (20) comprising a first surface (22a), a second surface (22b), a first edge (21a), and a second edge (21b), arranging a conductive wire (2) on the first surface of the first photovoltaic cell according to a certain pattern, and attaching the conductive wire to the first surface of the first photovoltaic cell with the aid of a first non-conductive yarn (5a) by stitching in the area of the first edge of the first photovoltaic cell according to a first stitch type.
H01L 31/05 - Moyens d’interconnexion électrique entre les cellules PV à l’intérieur du module PV, p.ex. connexion en série de cellules PV
H01L 31/0749 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV] caractérisés par au moins une barrière de potentiel ou une barrière de surface les barrières de potentiel étant uniquement du type PN à hétérojonction incluant un composé AIBIIICVI, p.ex. cellules solaires à hétérojonctions CdS/CuInSe2 [CIS]
A sensor device (10) for measuring a temperature in a photovoltaic laminate structure (20) and a sensor system (30) comprising such a sensor device (10) is provided. The sensor device (10) comprises: a capillary (12) for being embedded in the laminate structure (20) between two layers (22) thereof; a medium (14) arranged within the capillary (12); and an optical fiber (16) extending through the capillary (12) and surrounded by the medium (14), wherein at least a portion (17) of the optical fiber (16) has temperature-dependent transmission characteristics.
G01D 5/353 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensibleMoyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminéTransducteurs non spécialement adaptés à une variable particulière utilisant des moyens optiques, c.-à-d. utilisant de la lumière infrarouge, visible ou ultraviolette avec atténuation ou obturation complète ou partielle des rayons lumineux les rayons lumineux étant détectés par des cellules photo-électriques en modifiant les caractéristiques de transmission d'une fibre optique
G01K 11/3206 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou utilisant des changements dans la transmittance, la diffusion ou la luminescence dans les fibres optiques en des endroits distincts de la fibre, p. ex. utilisant la diffusion de Bragg
G01K 1/14 - SupportsDispositifs de fixationDispositions pour le montage de thermomètres en des endroits particuliers
G01L 1/24 - Mesure des forces ou des contraintes, en général en mesurant les variations des propriétés optiques du matériau quand il est soumis à une contrainte, p. ex. par l'analyse des contraintes par photo-élasticité
G01L 1/26 - Mesures auxiliaires prises, ou dispositifs utilisés en liaison avec le mesurage des forces, p. ex. pour empêcher l'influence des composantes transversales de la force, pour empêcher la surcharge
H02S 50/00 - Surveillance ou tests de systèmes PV, p. ex. équilibrage de charge ou identification des défauts
H02S 50/10 - Tests de dispositifs PV, p. ex. de modules PV ou de cellules PV individuelles
H02S 50/15 - Tests de dispositifs PV, p. ex. de modules PV ou de cellules PV individuelles utilisant des moyens optiques, e.g. utilisant l'électroluminescence
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Paper and cardboard; Artists' materials for drawing, Artists' materials, Drawing materials and materials for architects; Brush pens. Provision of training and education; Blended learning; Online training; E-learning; Provision of online tutorials; Recording of instructional videos; Providing of video tutorials. Design services relating to architecture; Graphic design; Technical drawing; Computer-aided engineering design and drawing services; services in the following fields: Architecture and Interior design; Design and development of computer software.
41.
PREFABRICATED BOARDING FOR CLADDING A WOODEN FRAME OF A BUILDING WITH WALLS AND METHOD FOR APPLYING SUCH A PREFABRICATED BOARDING TO A WOODEN FRAME
WOODINC, BESLOTEN VENNOOTSCHAP MET BEPERKTE AANSPRAKELIJKHEID (Belgique)
UNIVERSITEIT HASSELT (Belgique)
Inventeur(s)
Van De Heyning, Eric
Janssens, Bart
Abrégé
Prefabricated boarding (9) comprising the following elements: - one or several sandwich panels (11) comprising at least a first, thermally insulating layer (12) and a second layer, ensuring the stability of the wall; and, - one or several rubber strips (15) to cover a side (16) of the beams (2) and posts (3) against which such a sandwich panel (11) is applied.
E04B 1/68 - Étanchéités des joints, p. ex. des joints d'expansion
E04B 1/76 - Isolation thermique ou acoustique, absorption ou réflexion de la chaleur ou du sonAutres méthodes de construction procurant des conditions thermiques ou acoustiques favorables, p. ex. par accumulation de chaleur à l'intérieur des murs spécifiquement relatives à la chaleur uniquement
E04B 1/80 - Éléments calorifuges en forme de dalles
E04B 2/70 - Murs avec ossature d'encadrement ou poteletsMurs comportant des pièces allongées supportant la charge avec pièces allongées en bois
E04C 2/16 - Éléments de construction de relativement faible épaisseur pour la construction de parties de bâtiments, p. ex. matériaux en feuilles, dalles ou panneaux caractérisés par des matériaux spécifiés en bois, fibres, copeaux, tiges de végétaux ou analoguesÉléments de construction de relativement faible épaisseur pour la construction de parties de bâtiments, p. ex. matériaux en feuilles, dalles ou panneaux caractérisés par des matériaux spécifiés en matières plastiquesÉléments de construction de relativement faible épaisseur pour la construction de parties de bâtiments, p. ex. matériaux en feuilles, dalles ou panneaux caractérisés par des matériaux spécifiés en produits mousse en fibres, copeaux, tiges végétales ou analogues
E04B 7/22 - Toits constitués de dalles auto-portantes, p. ex. susceptibles d'être chargées les dalles ayant des propriétés isolantes, p. ex. dalles stratifiées avec des couches de matériaux isolants
E04B 1/74 - Isolation thermique ou acoustique, absorption ou réflexion de la chaleur ou du sonAutres méthodes de construction procurant des conditions thermiques ou acoustiques favorables, p. ex. par accumulation de chaleur à l'intérieur des murs
42.
METHOD AND MEANS FOR DIAGNOSIS OF SPONDYLOARTHRITIS
The present invention in general relates to the field of antibody profiling in spondyloarthritis. In particular, the inventors found that antibody levels against selected peptides are raised in spondylarthritis patients, and herein provide a diagnostic method and kit comprising such peptides for use in the diagnosis of spondyloarthritis.
G01N 33/564 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour complexes immunologiques préexistants ou maladies auto-immunes
The present invention is directed to a device for measurement of the rigidity and/or tumescence of a penis during a penile tumescent event. In particular, the device of the present invention comprises axial and/or radial monitoring means for monitoring the axial and/or radial tumescence and/or rigidity of a penis during a penile tumescent event. The present invention further also provides methods for monitoring the axial and/or radial tumescence and rigidity of a penis.
A localized smart energy management system comprises a plurality of controllable loads, at least one intermittent energy source, a selectively connectable dispatchable energy source, and optionally an energy storage system. A method for balancing power production and power consumption of such localized smart energy management systems in real time comprises performing a coarse-grained optimization in a first layer of a hierarchical optimization structure to generate a predicted schedule, based on long-term load demand profiles and long-term power generation profiles. A second layer iteratively refines the predicted schedule upon receiving a new forecast of a short-term power generation profile for the at least one intermittent energy source.
G06Q 10/04 - Prévision ou optimisation spécialement adaptées à des fins administratives ou de gestion, p. ex. programmation linéaire ou "problème d’optimisation des stocks"
G06Q 10/06 - Ressources, gestion de tâches, des ressources humaines ou de projetsPlanification d’entreprise ou d’organisationModélisation d’entreprise ou d’organisation
An intermediate structure for forming a semiconductor device and method of making is provided. The intermediate device includes (i) a substrate comprising a Ga-based layer, and (ii) optionally, a metal layer on the substrate; wherein at least one of the Ga-based layer and, if present, the metal layer comprises at least a surface region having an isoelectric point of less than 7, usually at most 6.
H01L 21/00 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de dispositifs à semi-conducteurs ou de dispositifs à l'état solide, ou bien de leurs parties constitutives
H01L 23/373 - Refroidissement facilité par l'emploi de matériaux particuliers pour le dispositif
C30B 25/18 - Croissance d'une couche épitaxiale caractérisée par le substrat
C30B 28/14 - Production de matériaux polycristallins homogènes de structure déterminée directement à partir de l'état gazeux par réaction chimique de gaz réactifs
H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives
H01L 23/48 - Dispositions pour conduire le courant électrique vers le ou hors du corps à l'état solide pendant son fonctionnement, p. ex. fils de connexion ou bornes
46.
Analysis of data obtained by fluorescence fluctuation microscopy from a plurality of dyes
Ludwig-Maximilians-Universität München (Allemagne)
Inventeur(s)
Hendrix, Jelle
Smisdom, Nick
Lamb, Don
Schrimpf, Waldemar
Abrégé
The analysis of data from fluorescence microscopy is disclosed, more especially fluorescence fluctuation microscopy, being a correlation analysis of fluctuation of the fluorescence intensity enabling quantitative and dynamic information capture. In particular the analysis is described of characteristics such as concentrations, mobility, interactions, stoichiometry, etc. of mixtures of particular that are fluorescently labeled with differently colored fluorophores having different excitation/emission spectra using fluctuation microscopy.
H01L 31/042 - Modules PV ou matrices de cellules PV individuelles
H02N 6/00 - Générateurs dans lesquels le rayonnement lumineux est directement converti en énergie électrique (cellules solaires ou ensembles de cellules solaires H01L 25/00, H01L 31/00)
H01G 9/00 - Condensateurs électrolytiques, redresseurs électrolytiques, détecteurs électrolytiques, dispositifs de commutation électrolytiques, dispositifs électrolytiques photosensibles ou sensibles à la températureProcédés pour leur fabrication
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
H01L 51/42 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement en énergie électrique, soit comme dispositifs de commande de l'énergie électrique par ledit rayonnement
48.
Methods for the preparation of cyclic imino ether polymers
Cyclic imino ether polymers, such as polyoxazolines or polyoxazines, having a low polydispersity index can be obtained in a tubular flow reactor by applying a sufficiently high linear flow velocity of the reaction mixture in the tubular flow reactor, such as a flow velocity of least 100 cm/min or at least 120 cm/min. Also, methods to control the polydispersity of a cyclic imino ether polymer during polymerization are provided.
A computer-implemented method and related device are disclosed for determining a plurality of operating scenarios of an energy system. The method comprises obtaining a plurality of performance measures of the energy system as a function of time corresponding to a plurality of sets of values of input variables. The method comprises clustering the plurality of sets of values of the input variables and the performance measures associated therewith into groups and defining a descriptor for each of the groups. The method also comprises outputting the descriptors of the groups for use in an online prediction or offline estimation of the energy system.
In a first aspect, the present disclosure relates to a method for forming a diamond membrane, comprising: providing a substrate having an amorphous dielectric layer thereon, the amorphous dielectric layer comprising an exposed surface, the exposed surface having an isoelectric point of less than 7, preferably at most 6; seeding diamond nanoparticles onto the exposed surface; growing a diamond layer from the seeded diamond nanoparticles; and removing a portion of the substrate from underneath the diamond layer, the removed portion extending at least up to the amorphous dielectric layer, thereby forming the diamond membrane over the removed portion.
H01L 21/32 - Traitement des corps semi-conducteurs en utilisant des procédés ou des appareils non couverts par les groupes pour former des couches isolantes en surface, p. ex. pour masquer ou en utilisant des techniques photolithographiquesPost-traitement de ces couchesEmploi de matériaux spécifiés pour ces couches en utilisant des masques
H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives
H01L 21/8238 - Transistors à effet de champ complémentaires, p.ex. CMOS
B01D 67/00 - Procédés spécialement adaptés à la fabrication de membranes semi-perméables destinées aux procédés ou aux appareils de séparation
The current invention relates to selective PDE4D inhibitors for use in the prevention and/or treatment of demyelinating diseases of the central nervous system and of the peripheral nervous system.
LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (Allemagne)
Inventeur(s)
Hendrix, Jelle
Smisdom, Nick
Lamb, Don
Schrimpf, Waldemar
Abrégé
The analysis of data from fluorescence microscopy is disclosed, more especially fluorescence fluctuation microscopy, being a correlation analysis of fluctuation of the fluorescence intensity enabling quantitative and dynamic information capture. In particular the analysis is described of characteristics such as concentrations, mobility, interactions, stoichiometry, etc. of mixtures of particles that are fluorescently labeled with differently colored fluorophores having different excitation/emission spectra using fluctuation microscopy.
A method for generating/updating a database of current-voltage characteristic curves is disclosed. This method includes simulating for at least one combination of a topology of a photovoltaic cell group, an internal cell temperature(s) and a cell irradiation(s), a model of the photovoltaic cell group to provide a representative current-voltage characteristic curve, and clustering the current-voltage characteristic curves to identify at least one plurality of similar current-voltage characteristic curves. The method also includes generating a many-to-one mapping in the database to map query requests corresponding to each of the at least one plurality of similar current-voltage characteristic curves onto a single representative current-voltage characteristic curve for that plurality, each query request identifying a topology of a photovoltaic cell group, at least one internal temperature for the photovoltaic cells in the photovoltaic cell group and at least one cell irradiation for the photovoltaic cells in the photovoltaic cell group.
A method for detecting the presence of or quantification of carbon black and/or black carbon in a sample or carrier medium. The method includes providing the sample or carrier medium without labelling or pre-treatment of the carbon black and/or black carbon particles; illuminating the sample or carrier medium at a temperature below 90° C. by a pulsed light with a pulse duration below 500 femtoseconds, a repetition rate above 1 MHz with an average power below 20 mW, and a wavelength of a femtosecond laser pulse ranging from 700 to 1200 nm, to generate non-incandescence related light emission from the carbon black and/or black carbon particles; and analysis of the light emission.
G01N 21/63 - Systèmes dans lesquels le matériau analysé est excité de façon à ce qu'il émette de la lumière ou qu'il produise un changement de la longueur d'onde de la lumière incidente excité optiquement
G01J 1/58 - Photométrie, p. ex. posemètres photographiques en utilisant une luminescence produite par la lumière
B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p. ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires
G01N 15/00 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux
G01N 15/06 - Recherche de la concentration des suspensions de particules
56.
Method for immobilizing molecularly imprinted polymers
In a first aspect, the present disclosure relates to a method for immobilizing a molecularly imprinted polymer onto a substrate, comprising providing a substrate having an amorphous carbon surface; and grafting the molecularly imprinted polymer onto the amorphous carbon surface.
C08F 292/00 - Composés macromoléculaires obtenus par polymérisation de monomères sur des substances inorganiques
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/531 - Production de matériaux de tests immunochimiques
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
57.
PARTIALLY TRANSLUCENT PHOTOVOLTAIC MODULES AND METHODS FOR MANUFACTURING
The present invention provides thin film photovoltaic modules of a predetermined size that may be relatively large, e.g. having dimensions up to 4 m by 2 m, wherein the photovoltaic modules may be non-translucent or partially translucent, e.g. partially transparent, and methods for fabricating such thin film photovoltaic modules. In embodiments of the present invention the thin film photovoltaic modules comprise a plurality of photovoltaic plates positioned side by side, the plurality of photovoltaic plates within a photovoltaic module being electrically interconnected with each other by means of connection elements comprising a plurality of electrically conductive wires. The present invention further provides methods for forming electrical interconnections between photovoltaic plates within such thin film photovoltaic modules, wherein electrical connection elements comprising a plurality of electrically conductive wires are used for forming electrical interconnections between photovoltaic plates.
H01L 31/05 - Moyens d’interconnexion électrique entre les cellules PV à l’intérieur du module PV, p.ex. connexion en série de cellules PV
H01L 31/0445 - Modules PV ou matrices de cellules PV individuelles comportant des cellules solaires en couches minces, p.ex. cellules solaires en a-Si, CIS ou CdTe
09 - Appareils et instruments scientifiques et électriques
35 - Publicité; Affaires commerciales
38 - Services de télécommunications
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Databases, not in the field of individual, team and organisational development and HR consulting, conflict and stress management, psychometric testing or testing by psychological type theory; computer and game programs, not in the field of individual, team and organisational development and HR consulting, conflict and stress management, psychometric testing or testing by psychological type theory; software, not in the field of individual, team and organisational development and HR consulting, conflict and stress management, psychometric testing or testing by psychological type theory; application software [apps] [stored and downloadable] for computers, not in the field of individual, team and organisational development and HR consulting, conflict and stress management, psychometric testing or testing by psychological type theory; laptops; tablets; smart phones and mobile devices. Advertising; publicity. Providing access to information stored in databases, including on the Internet and in particular by means of interactive computer systems; Telecommunications by means of platforms and portals on the internet; leasing access time to databases. Education, not in the field of individual, team and organisational development and HR consulting, conflict and stress management, psychometric testing or testing by psychological type theory; education services relating to academic research; education information; organization of educational events relating to academic research; publishing relating to academic research; publishing services relating to academic research. Server hosting; scientific research; platform as a service [PaaS]; hosting computer sites [web sites]; hosting platforms on the internet.
59.
Methods to detect non-genotoxic carcinogens using flatworms
This disclosure relates to predicting the carcinogenicity of compounds. More in particular, this application discloses methods to detect whether a compound is a non-genotoxic carcinogen and methods to discriminate between genotoxic and non-genotoxic carcinogens based on in vivo stem cell proliferation patterns in flatworms.
G01N 31/00 - Recherche ou analyse des matériaux non biologiques par l'emploi des procédés chimiques spécifiés dans les sous-groupesAppareils spécialement adaptés à de tels procédés
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
60.
Magnetometer sensor with negatively charged nitrogen-vacancy centers in diamond
The disclosure relates to a magnetometer sensor with negatively charged nitrogen-vacancy centers in diamond. One example embodiment is a magnetometer sensor. The magnetometer sensor includes a diamond crystal with one or more negatively charged nitrogen-vacancy centers. The magnetometer sensor also includes one or more light sources. Further, the magnetometer sensor includes an electrode. In addition, the magnetometer sensor includes a read-out module. The read-out module includes a read-out circuit configured to read-out a photocurrent from the electrode and a lock-in amplifier. The lock-in amplifier includes a first input, a second input, and an output. The magnetometer sensor additionally includes a microwave source configured to apply a microwave field to the negatively charged nitrogen-vacancy centers. The microwave source includes a microwave generator for generating continuous wave microwaves and a microwave modulator configured to modulate the continuous wave microwaves. Still further, the magnetometer sensor includes a processor.
G01R 33/26 - Dispositions ou appareils pour la mesure des grandeurs magnétiques faisant intervenir la résonance magnétique pour la mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques utilisant le pompage optique
G01R 33/36 - Détails électriques, p. ex. adaptations ou couplage de la bobine au récepteur
G01R 33/60 - Dispositions ou appareils pour la mesure des grandeurs magnétiques faisant intervenir la résonance magnétique utilisant la résonance paramagnétique électronique
In a first aspect, the present invention relates to the use of a micelle of an amphiphilic block copolymer to modify a cell, wherein the amphiphilic block copolymer comprises one or more hydrophobic blocks and one or more hydrophilic blocks, wherein at least one block comprises a conjugated polymer, and wherein the micelle is optionally loaded with a compound therein.
A61K 47/32 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. carbomères
C08F 293/00 - Composés macromoléculaires obtenus par polymérisation sur une macromolécule contenant des groupes capables d'amorcer la formation de nouvelles chaînes polymères rattachées exclusivement à une ou aux deux extrémités de la macromolécule de départ
C08G 61/02 - Composés macromoléculaires contenant uniquement des atomes de carbone dans la chaîne principale de la molécule, p. ex. polyxylylènes
62.
METHODS FOR THE PREPARATION OF CYCLIC IMINO ETHER POLYMERS
Cyclic imino ether polymers, such as polyoxazolines or polyoxazines, having a low polydispersity index can be obtained in a tubular flow reactor by applying a sufficiently high linear flow velocity of the reaction mixture in the tubular flow reactor, such as a flow velocity of least 100 cm/min or at least 120 cm/min. Also, methods to control the polydispersity of a cyclic imino ether polymer during polymerization are provided.
KATHOLIEKE UNIVERSITEIT LEUVEN KU LEUVEN RESEARCH & DEVELOPMENT (Belgique)
UNIVERSITEIT HASSELT (Belgique)
Inventeur(s)
Ameloot, Marcel
Bové, Hannelore
Nawrot, Tim
Roeffaers, Maarten
Steuwe, Christian
Vandeven, Martin
Abrégé
The present invention is based on non-incandescence related emission generation by carbonaceous particles (e.g. carbon black (CB) and black carbon (BC) particles) under illumination with pulsed light. The pulse duration is sufficiently short to trigger an instantaneous sample response without emission of heat-induced sample incandescence. The unique property of the described emission by carbonaceous particles upon pulsed illumination allows label-free optical detection and localization of carbonaceous particles in fluids, cells and tissues of biological and carrier media of non-biological origin. A method for analysing carbonaceous particles in fluids, cells and tissues of biological and carrier media of non-biological origin is also disclosed. An apparatus for analysing carbonaceous particles in fluids, cells and tissues of biological and carrier media of non-biological origin is disclosed that includes: a measurement specimen distribution section for distributing a liquid control sample and a predefined aliquot of liquid sample together with sheath fluid; an optical detecting section comprising of a femtosecond pulsed laser for illumination of the measurement specimen, a forward light receiving element for detecting forward light emitted from the specimen, and a backward light receiving element for detecting backward emitted light from the specimen; and a measurement section for measuring carbonaceous particles in liquids, cells and tissues, based on light detected by the optical detecting section.
G01N 21/63 - Systèmes dans lesquels le matériau analysé est excité de façon à ce qu'il émette de la lumière ou qu'il produise un changement de la longueur d'onde de la lumière incidente excité optiquement
G01N 15/06 - Recherche de la concentration des suspensions de particules
The disclosure relates to a method for forming a conformal coating on a substrate having a topography presenting a relief. One method of the disclosure includes setting the temperature of the substrate within the range 140-275° C., and coating an aqueous solution including a sol-gel precursor on said substrate. The disclosure also relates to a method for fabricating a battery, a capacitor, a catalyst, a photovoltaic cell or a sensor using such a method, and to an aqueous solution for use in such a method.
C23C 18/12 - Revêtement chimique par décomposition soit de composés liquides, soit de solutions des composés constituant le revêtement, ne laissant pas de produits de réaction du matériau de la surface dans le revêtementDépôt par contact par décomposition thermique caractérisée par le dépôt sur des matériaux inorganiques, autres que des matériaux métalliques
B05D 1/02 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces réalisés par pulvérisation
B05D 3/04 - Traitement préalable des surfaces sur lesquelles des liquides ou d'autres matériaux fluides doivent être appliquésTraitement ultérieur des revêtements appliqués, p. ex. traitement intermédiaire d'un revêtement déjà appliqué, pour préparer les applications ultérieures de liquides ou d'autres matériaux fluides par exposition à des gaz
H01G 9/042 - Électrodes caractérisées par le matériau
H01M 4/131 - Électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p. ex. LiCoOx
H01M 4/1391 - Procédés de fabrication d'électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p. ex. LiCoOx
H01M 4/525 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de nickel, de cobalt ou de fer d'oxydes ou d'hydroxydes mixtes contenant du fer, du cobalt ou du nickel pour insérer ou intercaler des métaux légers, p. ex. LiNiO2, LiCoO2 ou LiCoOxFy
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
H01M 10/0585 - Structure ou fabrication d'accumulateurs ayant uniquement des éléments de structure plats, c.-à-d. des électrodes positives plates, des électrodes négatives plates et des séparateurs plats
36 - Services financiers, assurances et affaires immobilières
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Printed matter, Including books, Courses, Leaflets, Newspapers, Magazines [periodicals]; Instructional material and other teaching material (except apparatus). Luggage, bags, wallets and other carriers; Parasols and umbrellas; Trunks and travelling bags. Clothing, footwear, headgear. Advertising; Business management; Business administration; Office functions. Insurance; Financial affairs; Monetary affairs; Real estate affairs; Fundraising and sponsorship; Venture capital financing. Education and teaching services; Providing of training; Publication and distribution of printed matter; Library services; Sporting and cultural activities; Arranging of lectures, seminars, courses and congresses of an educational nature. Scientific and technological services and research and design relating thereto; Industrial analysis and research services; Design and development of computer hardware and software.
36 - Services financiers, assurances et affaires immobilières
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Printed matter, Including books, Courses, Leaflets, Newspapers, Magazines [periodicals]; Instructional material and other teaching material (except apparatus). Luggage, bags, wallets and other carriers; Parasols and umbrellas; Trunks and travelling bags. Clothing, footwear, headgear. Advertising; Business management; Business administration; Office functions. Insurance; Financial affairs; Monetary affairs; Real estate affairs; Fundraising and sponsorship; Venture capital financing. Education and teaching services; Providing of training; Publication and distribution of printed matter; Library services; Sporting and cultural activities; Arranging of lectures, seminars, courses and congresses of an educational nature. Scientific and technological services and research and design relating thereto; Industrial analysis and research services; Design and development of computer hardware and software.
67.
METHODS TO DETECT NON-GENOTOXIC CARCINOGENS USING FLATWORMS
The present invention relates to predicting the carcinogenicity of compounds. More in particular, the present invention discloses methods to detect whether a compound is a non-genotoxic carcinogen and methods to discriminate between genotoxic and non-genotoxic carcinogens based on in vivo stem cell proliferation patterns in flatworms.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
68.
AUTOMATED DESIGN AND GENERATING OF AN ELECTRONIC SYSTEM ON A FLEXIBLE SUBSTRATE
Design and fabrication methods, related systems and computer hardware and software are provided, enabling designers without any technical background to produce stand-alone paper artifacts augmented with electronics.
The invention relates to telecommunication methods, computer program products, non-transitory machine readable storage medium, graphical user interfaces, usage of those methods and devices, in particular for communicating a message from a first location to a second location, the method comprising the steps of: (i) inputting on a first processing engine on said first location the message; (ii) visually deforming the message; (iii) transmitting said deformed message to said second location; (iv) receiving on a second processing engine said deformed message and displaying it; whereby the degree of deforming in the first processing engine is selected to still allow recognition of the message on the display by a second user of the second processing engine while substantially increasing the processing effort to be used for automated recognition of the message by third processing engines when they would also come in the possession of the deformed message.
The present invention relates to a method for forming a conformal coating on a substrate having a topography presenting a relief, said method comprising the steps of: a. Setting the temperature of the substrate within the range 140- 275 °C, and b. coating an aqueous solution comprising a sol-gel precursor on said substrate; It also relates to a method for fabricating a battery, a capacitor, a catalyst, a photovoltaic cell or a sensor comprising such a method, and to an aqueous solution for use in such a method.
C23C 18/12 - Revêtement chimique par décomposition soit de composés liquides, soit de solutions des composés constituant le revêtement, ne laissant pas de produits de réaction du matériau de la surface dans le revêtementDépôt par contact par décomposition thermique caractérisée par le dépôt sur des matériaux inorganiques, autres que des matériaux métalliques
A method an system is disclosed for the detection and/or allocation of at least one point mutation in target DNA and/or RNA duplexes. The method comprises obtaining a functionalized surface which is coated with probe DNA and/or RNA whereto target DNA and/or RNA duplexes are attached, contacting said functionalized surface to an electrolytic solution having a neutral pH in a flow cell and measuring a first impedance value within said electrolytic solution, and then adding a chemical to the electrolytic solution which is able to achieve denaturation of the target DNA and/or RNA. The method further comprises measuring a second impedance value within the flow cell after completion of the denaturation of the DNA and/or RNA target, and then obtaining a value representative for the impact of the chemical on the impedance of the electrolytic solution. The amount and/or allocation of point mutation(s) within the target DNA and/or RNA is then determined by calculating the denaturation-time constant based on the difference between the first and second impedance value and taking into account the impact of the chemical by third impedance value.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 27/02 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G05B 15/02 - Systèmes commandés par un calculateur électriques
72.
Method for cleaning and passivating chalcogenide layers
Katholieke Universiteit Leuven, KU Leuven R&D (Belgique)
Universiteit Hasselt (Belgique)
Inventeur(s)
Buffiere, Marie
Meuris, Marc
Brammertz, Guy
Abrégé
A method for chemically cleaning and passivating a chalcogenide layer is provided, wherein the method comprises bringing the chalcogenide layer into contact with an ammonium sulfide containing ambient, such as an ammonium sulfide liquid solution or an ammonium sulfide containing vapor. Further, a method for fabricating photovoltaic cells with a chalcogenide absorber layer is provided, wherein the method comprises: providing a chalcogenide semiconductor layer on a substrate; bringing the chalcogenide semiconductor layer into contact with an ammonium sulfide containing ambient, thereby removing impurities and passivating the chalcogenide semiconductor layer; and afterwards providing a buffer layer on the chalcogenide semiconductor layer.
H01L 31/18 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
H01L 31/0749 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV] caractérisés par au moins une barrière de potentiel ou une barrière de surface les barrières de potentiel étant uniquement du type PN à hétérojonction incluant un composé AIBIIICVI, p.ex. cellules solaires à hétérojonctions CdS/CuInSe2 [CIS]
H01L 31/032 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés non couverts par les groupes
H01L 31/072 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV] caractérisés par au moins une barrière de potentiel ou une barrière de surface les barrières de potentiel étant uniquement du type PN à hétérojonction
H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives
73.
Heat-transfer resistance based analysis of bioparticles
A bio-sensing device suitable for the detection and/or characterization of target bioparticles and corresponding method is described. The bio-sensing technique is based on the impact on the heat transfer resistivity value of bioparticles binding in binding cavities of a structured substrate. By sensing temperatures and determining a heat transfer resistivity value based thereon, a characteristic of the target bioparticles can be derived.
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G01N 25/18 - Recherche ou analyse des matériaux par l'utilisation de moyens thermiques en recherchant la conductivité thermique
74.
Heat-transfer resistance based analysis bioparticles
A method an system is disclosed for characterizing DNA and/or RNA duplexes. The biosensing device comprises a heating element using a power and being suitable for providing thermal denaturation of target DNA and/or RNA bioparticles, a sample holder adapted for receiving a biocompatible substrate having a functionalized surface which is coated with probe DNA and/or RNA whereto target DNA and/or RNA duplexes can be attached, the sample holder further being adapted for exposing the biocompatible substrate at one side to the heating element, a first temperature sensing element for sensing a temperature at the side where the biocompatible substrate can be exposed to the heating element and a second temperature sensing element for sensing a temperature at the side opposite thereto with respect to the biocompatible substrate. The device also comprises a processing means programmed for calculating at least one heat transfer resistivity value based on temperature values obtained with the first temperature sensing element and the second temperature sensing element and the power for the heating element, for deriving a characteristic of the target DNA and/or RNA bioparticles from said heat transfer resistivity value.
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
C07H 21/02 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le ribosyle comme radical saccharide
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
G01N 15/06 - Recherche de la concentration des suspensions de particules
G01N 27/00 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques
G01N 25/00 - Recherche ou analyse des matériaux par l'utilisation de moyens thermiques
A method an system is disclosed for the detection and/or allocation of at least one point mutation in target DNA and/or RNA duplexes. The method comprises obtaining a functionalized surface which is coated with probe DNA and/or RNA whereto target DNA and/or RNA duplexes are attached, contacting said functionalized surface to an electrolytic solution having a neutral pH in a flow cell and measuring a first impedance value within said electrolytic solution, and then adding a chemical to the electrolytic solution which is able to achieve denaturation of the target DNA and/or RNA. The method further comprises measuring a second impedance value within the flow cell after completion of the denaturation of the DNA and/or RNA target, and then obtaining a value representative for the impact of the chemical on the impedance of the electrolytic solution. The amount and/or allocation of point mutation(s) within the target DNA and/or RNA is then determined by calculating the denaturation-time constant based on the difference between the first and second impedance value and taking into account the impact of the chemical by third impedance value.
G01N 15/06 - Recherche de la concentration des suspensions de particules
G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 27/02 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance
The present invention provides novel biomarkers which can be used to determine the joint destruction progression rate in rheumatoid arthritis patients. The biomarker can be used to determine a group of RA patients who can benefit from improved administration schedules of rheumatoid arthritis drugs. In addition, the invention provides kits for determining the biomarker of the invention.
G01N 33/564 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour complexes immunologiques préexistants ou maladies auto-immunes
A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
The present invention relates to a method (1) for creating a diamond structure (38) on a substrate (31). This method comprises the steps of providing (2) a substrate (31), providing (3) a mold (25) on the substrate (31), providing (4) a diamond seed solution (34) in the mold (25), and removing (6) the mold (25) such that a diamond structure (38) remains on the substrate (31).
A method an system is disclosed for the detection and/or allocation of at least one point mutation in target DNA and/or RNA duplexes. The method comprises obtaining a functionalized surface which is coated with probe DNA and/or RNA whereto target DNA and/or RNA duplexes are attached, contacting said functionalized surface to an electrolytic solution having a neutral pH in a flow cell and measuring a first impedance value within said electrolytic solution, and then adding a chemical to the electrolytic solution which is able to achieve denaturation of the target DNA and/or RNA. The method further comprises measuring a second impedance value within the flow cell after completion of the denaturation of the DNA and/or RNA target, and then obtaining a value representative for the impact of the chemical on the impedance of the electrolytic solution. The amount and/or allocation of point mutation(s) within the target DNA and/or RNA is then determined by calculating the denaturation-time constant based on the difference between the first and second impedance value and taking into account the impact of the chemical by third impedance value.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 27/02 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance
A method an system is disclosed for characterising DNA and/or RNA duplexes. The biosensing device comprises a heating element using a power and being suitable for providing thermal denaturation of target DNA and/or RNA bioparticles, a sample holder adapted for receiving a biocompatible substrate having a functionalized surface which is coated with probe DNA and/or RNA whereto target DNA and/or RNA duplexes can be attached, the sample holder further being adapted for exposing the biocompatible substrate at one side to the heating element, a first temperature sensing element for sensing a temperature at the side where the biocompatible substrate can be exposed to the heating element and a second temperature sensing element for sensing a temperature at the side opposite thereto with respect to the biocompatible substrate. The device also comprises a processing means programmed for calculating at least one heat transfer resistivity value based on temperature values obtained with the first temperature sensing element and the second temperature sensing element and the power for the heating element, for deriving a characteristic of the target DNA and/or RNA bioparticles from said heat transfer resistivity value.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 25/18 - Recherche ou analyse des matériaux par l'utilisation de moyens thermiques en recherchant la conductivité thermique
The present invention relates to a panel of metabolites in a body fluid sample that can be used for the diagnosis of breast, lung, colon and prostate cancer. More specifically, the invention relates to the NMR analysis of a urine or blood sample, whereby the simultaneous determination of the concentration of a panel of metabolites allows the diagnosis of breast, lung, colon or prostate cancer with a high sensitivity and specificity. In particular, the panel of metabolites comprises methyl histidine and proline.
G01R 33/465 - Spectroscopie RMN appliquée à du matériau biologique, p. ex. tests in vitro
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
The present invention relates to a modified phage display, allowing the specific detection of citrullinated proteins. More specifically, the invention relates to a method for citrullinating proteins displayed by phage, without losing phage infectivity, and the detection of those proteins by biopanning. In a preferred embodiment, said phage is a T7 phage.
The invention relates to new monomers and polymers as well as blends of such polymers with an electron acceptor. The invention also relates to a blend for use in a photovoltaic device, comprising: (a) a polymer comprising monomer units according to the formula (I), wherein L' is selected from the group consisting of L-C(O)O-J, L-C(O)NR'-J, L-OCO-J', L-NR'CO-J', L-SCO-J', L-O-J, L-S-J, L-Se-J, L-NR'-J and L-CN wherein L is a linear or branched alkylene group having from 1 to 10 carbon atoms, wherein J is a hydrogen atom or a linear or branched alkyl group having from 1 to 4 carbon atoms, wherein J' is a group having from 1 to 10 carbon atoms, being saturated or unsaturated, linear or branched, comprising a phenyl unit or not comprising a phenyl unit, wherein R' is a hydrogen atom or a linear or branched alkyl group having from 1 to 4 carbon atoms, and (b) an electron acceptor such as a fullerene derivative.
C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
83.
METHODS FOR CONTROLLING THE CRYSTALLINE NANOFIBRE CONTENT OF ORGANIC LAYERS USED IN ORGANIC ELECTRONIC DEVICES
The present invention relates in a first aspect to methods for producing a nanofibres-containing layer for use as an active layer in an organic electronic device. The method comprising the steps of: a) first heating up a nanofibre-forming polymer in a solvent at a temperature T1, then b) cooling said solution down to a temperature T2 at a rate less than 40°C/h thereby forming a dispersion comprising crystalline nanofibres of said nanofibre-forming polymer, then c) raising the temperature of said dispersion to a temperature T3 higher than T2, but lower than said temperature T1, and then d) coating said dispersion on a substrate at said temperature T3 thereby forming a layer for use as an element of said organic electronic device, wherein before step (d), a step of adding an electron acceptor to the solution or dispersion is performed.
H01L 51/42 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement en énergie électrique, soit comme dispositifs de commande de l'énergie électrique par ledit rayonnement
84.
POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES
This invention provides monomeric compounds represented by the structural formula (I) or the structural formula (II) which can be polymerized into crosslinkable polymers useful for producing opto-electronic devices.
C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
The present invention relates to the diagnosis of autoimmune disorders, more specifically to the diagnosis of rheumatoid disorders, chronic autoimmune arthritis and even more specifically to the diagnosis of rheumatoid arthritis. A biomarker panel is provided which can be used to detect if a subject has rheumatoid arthritis. Also described are methods of identification of such biomarkers.
C07K 16/00 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux
G01N 33/564 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour complexes immunologiques préexistants ou maladies auto-immunes
86.
METHOD FOR THE PRODUCTION OF A LAYER OF ORGANIC MATERIAL
INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM VZW (Belgique)
UNIVERSITEIT HASSELT (Belgique)
Inventeur(s)
Aernouts, Tom
Krebs, Frederik, Christian
Vanlaeke, Peter
Abrégé
The present invention provides a method for producing a layer of organic material. The method comprises providing onto a substrate, under deposition conditions, a layer of a solution comprising said organic material dissolved in a solvent; optionally partially drying said layer of solution; thereafter annealing said layer of solution, said annealing being applied before said layer of solution has been dried out completely and the duration of said annealing being limited such that said layer of solution is not dried out completely during the annealing, said annealing inducing reflow of said layer of solution; and thereafter drying out said layer of solution, said drying out being controlled such that it is performed slower than it would be under deposition conditions. The resulting layer of organic material shows an improvement of both the micro quality and the macro quality, leading to obtaining a fully continuous film with minor surface roughness and an accurate line resolution and edge definition.
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives