CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI (INSTM) (Italie)
Inventeur(s)
Bontempi, Elza
Depero, Laura Eleonora
Fahimi, Ario
Frontera, Patrizia
Abrégé
A method for recovering materials from waste or scraps through an improved microwave carbothermal process involves combining reagents of a carbothermal reaction to form a mixture to be subjected to heat treatment, the reagents including a component in which an element to be recovered is contained and a carbon-containing component, the component being contained within a waste material, placing the mixture in a crucible, placing the crucible in a refractory chamber having a side wall, a surface of the side wall being covered by a layer of microwave-sensitive material, and inserting the refractory chamber into a microwave oven. The carbothermal reaction is obtained in less time and with lower electricity consumption compared to typical carbothermal reactions.
There is described a set of antisense oligonucleotides suitable for inducing exon skipping on a pre-mature RNA transcript (pre-mRNA) from a human Granulin gene (GRN) carrying a null mutation. There are further described a pharmaceutical composition comprising said set of antisense oligonucleotides and the therapeutic use of said oligo set and/or pharmaceutical composition, particularly for the prevention and/or therapeutic treatment of a neurodegenerative disease such as frontotemporal dementia (FTD).
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
3.
RECOGNITION DEVICE FOR A RACK AND RACK FOR CONTAINING STORAGE BOXES INSIDE A REFRIGERATED STORAGE UNIT
The invention consists of a recognition device (1) for a rack (100) for containing storage boxes inside a cold storage unit (500), wherein the recognition device (1) comprises a main body (2) comprising an upper surface (22) and a lower surface (24); and at least one recognition element (3) protruding or recessed with respect to the upper surface (22).
The present invention describes compounds of formula (A) for use as Parkinson's disease modifying-agents, said formula (A). Surprisingly it has been found that the compounds of the invention can significantly reduce alpha-synuclein aggregation and stimulate the functional interaction between alpha-synuclein and Synapsin III.
The present invention describes compounds of formula (A) for use as Parkinson's disease modifying-agents, said formula (A). Surprisingly it has been found that the compounds of the invention can significantly reduce alpha-synuclein aggregation and stimulate the functional interaction between alpha-synuclein and Synapsin III.
CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI (INSTM) (Italie)
Inventeur(s)
Bontempi, Elza
Depero, Laura Eleonora
Fahimi, Ario
Frontera, Patrizia
Abrégé
The method according to the present invention comprises the steps of : - combining the reagents of a carbothermal reaction to form a mixture to be subjected to heat treatment, said reagents comprising the component (MO) in which the element (M) to be recovered and the carbon- containing component (C) are contained; the component (MO) is contained within a waste material; - placing the mixture in a crucible, and placing the crucible in a refractory chamber (2) having a side wall (23), the surface of which is covered by a layer (5) of microwave-sensitive material; - inserting the refractory chamber (2) into a microwave oven operated at a power W for a time T. The innovation of the present method consists in being able to obtain the carbothermal reaction in less time than shown in the literature (such as 15 minutes against 60 minutes tested with the use of rotary pilot ovens) and with lower electricity consumption.
ipartialiiiiiiiiiiii) with the video display terminal (VDT) through the input peripherals (20) comprises various combinations of the time traces which represent the sequence of the partial activity intervals, i.e. referring to the single interaction with the VDT (attentive observation of the monitor or the usage of the single peripheral) in which the combinations comprise operations such as AND, OR or combinations thereof.
33240.522 and an alkyl epoxide, preferably containing at least 3 atoms of carbon, said polyalkylene carbonate being characterised by chemical-physical and mechanical properties which make it advantageous for a variety of different applications.
xyz233244)0.5, halide, and acetyl acetonate (AcAc), 2x = y + z; wherein x is comprised between 1 and 5, y is comprised between 1 and 8, z is comprised between 1 and 2, and n is comprised between 0 and 20.
The present invention describes compounds of formula (A) for use as Parkinson's disease modifying-agents, said formula (A). Surprisingly it has been found that the compounds of the invention can significantly reduce alpha-synuclein aggregation and stimulate the functional interaction between alpha-synuclein and Synapsin III.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
FONDAZIONE DELLA COMUNITA' BRESCIANA ONLUS (Italie)
Inventeur(s)
Sartore, Luciana
Russo, Domenico
Pandini, Stefano
Nicolai, Piero
Ferrari, Marco
Gilbert, Ralph
Irish, Jonathan
Abrégé
An integrated core-shell bioactive structure which is used in the field of tissue engineering to promote tissue regeneration, in particular of bone and osteochondral tissues, and a process for the production thereof are described.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A system (1; 100; 200) for biological assay includes: - a first plate (2; 102; 202) comprising a plurality of protrusions (4; 104; 204), - a second plate (3) configured for mating with said first plate (2; 102; 202), the second plate comprising a plurality of receptacles, each receptacle being configured to receive at least a portion of a corresponding one of said protrusions upon mating of the first plate with the second plate, wherein each protrusion comprises a gate electrode (7; 106; 207) configured for facing the respective receptacle (5) upon mating of the first plate with the second plate. Each receptacle (5) further includes at least one source-drain channel operatively associated to a gate electrode (7; 106; 207) carried by a respective protrusion (4; 104; 204) upon mating of the first plate (2; 102; 202) with the second plate (3).
G01N 27/414 - Transistors à effet de champ sensibles aux ions ou chimiques, c.-à-d. ISFETS ou CHEMFETS
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
13.
METHOD FOR DETERMINING THE RECEPTION TIME OF ELECTROMAGNETIC SIGNALS
G01S 11/02 - Systèmes pour déterminer la distance ou la vitesse sans utiliser la réflexion ou la reradiation utilisant les ondes radioélectriques
H04L 27/26 - Systèmes utilisant des codes à fréquences multiples
14.
PROCESS FOR OBTAINING A POROUS MATERIAL FROM POWDER MATERIALS, A POROUS MATERIAL AND USE THEREOF FOR THE CAPTURE OF ATMOSPHERIC PARTICULATE MATTER AND ORGANIC CONTAMINANTS
CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI (Italie)
UNIVERSITÀ DEGLI STUDI DI BRESCIA (Italie)
Inventeur(s)
Bontempi, Elza
Depero, Laura Eleonora
Treccani, Laura
Zanoletti, Alessandra
Abrégé
The present invention relates to a process for the production of a porous, ceramic or vitreous material, from powder materials, preferably waste materials. According to a different embodiment, the present invention relates to a process for applying a coating of a porous material obtained from powder materials, preferably waste materials, to a pre-existing solid surface. The alternative processes according to the present invention provide for the steps of mixing under stirring a solvent, a binder, and a cross-linking agent until a gelling solution is obtained, and adding to said solution a powder material, and a chemical leavening agent to obtain a homogeneous mixture, which is heated at low temperature until a porous solid material is obtained. The present invention also relates to a porous, ceramic or vitreous material, comprising a generally amorphous phase, in turn comprising inorganic oxides, and a binder, obtainable by a process according to the invention, suitable for the capture of atmospheric particulate matter and organic contaminants.
Method of generation of diagnostic index for Alzheimer's disease provides for stimulating subject using transcranial magnetic stimulation with conditioning stimulus and, after first predetermined time interval, with control stimulus and to record amplitude of first motor evoked potential generated as result of such conditioning and control stimuli. Second conditioning stimulus is administered after second predetermined time interval greater than first predetermined time interval, allowing recording amplitude of second motor evoked potential. Third conditioning stimulus is administered using nervous electrical stimulation after third predetermined time interval, allowing recording amplitude of third motor evoked potential generated as result of third conditioning stimulus. Subsequently, method provides for generating diagnostic index on basis of processing of such first, second and third recorded motor evoked potential.
The present invention relates to an energy-saving method for a wireless device in a telecommunication network. The method comprises: receiving at least one part of a data transmission with information concerning duration, destination direction and direction of the transmitter of the transmission; determining compliance with a set of conditions, which comprises at least determining, according to the destination direction, that the transmission is not directed to the device; determining, in the case that the conditions are met, whether a sum of times exceeds a minimum shutdown time pre-set according to hardware limitations of the device, the sum of time comprising at least one counter set according to the information concerning duration; and performing, in the case that the sum exceed said minimum time, a micro-shutdown of the device with a duration equal to the value of the sum of times.
An anti-seismic dissipative device is described, comprising a first element (11) and a second element (12). Said second element (12) is adapted to be forced within said first element (11) generating a friction adapted to brake the mutual sliding between the structural elements (2) to which said device (1) is fastened.
E04H 9/02 - Bâtiments, groupes de bâtiments ou abris conçus pour résister à des situations extérieures anormales, p. ex. à des bombardements, à des séismes ou à des climats extrêmes, ou pour se protéger de ces situations résistant aux séismes ou à l'effondrement du sol
F16F 15/02 - Suppression des vibrations dans les systèmes non rotatifs, p. ex. dans des systèmes alternatifsSuppression des vibrations dans les systèmes rotatifs par l'utilisation d'organes ne se déplaçant pas avec le système rotatif
18.
METHOD AND CONTROL DEVICE FOR MANAGING REMOTE SENSOR OR ACTUATORS
A new architecture for supporting the development of sensors network application in Android environment has been proposed and experimentally tested. The system is divided in two main parts: one, called 'FW stage', a tool for programming and addressing the remote sensors; and the other one, called 'SW stage', a framework for allowing Android developers to handle remote sensors as they would be embedded ones.
A brickwork wall (100,200) suitable to accommodate the seismic deformation of a bearing structure (3) is divided into bands (101,201) linked together by sliding joints (102,202) shaped to ensure stability out of plane. Said joints (102,202) are constrained to the bearing structure (3) so as to also act as shear connection joints, preferably shear and tensile. This system is applicable both to walls (100) with vertical bands (101) and vertical joints (102) and walls (200) with horizontal bands (201) and horizontal joints (202). The invention also relates to a method of seismic reinforcement of an existing wall using the system of vertical bands (101) and vertical joints (102). The invention also relates to a wall (200) divided into horizontal bands (201) with horizontal sliding joints (202), in which each band (201) is connected to pillars (301) of the bearing structure (3) with an intermediate joint (204) placed in the middle.
E04H 9/02 - Bâtiments, groupes de bâtiments ou abris conçus pour résister à des situations extérieures anormales, p. ex. à des bombardements, à des séismes ou à des climats extrêmes, ou pour se protéger de ces situations résistant aux séismes ou à l'effondrement du sol
E04B 2/02 - Murs, p. ex. cloisons, pour bâtimentsStructure des murs en ce qui concerne l'isolationAssemblages spécifiques pour les murs édifiés par couches successives d'éléments de construction
E04C 2/04 - Éléments de construction de relativement faible épaisseur pour la construction de parties de bâtiments, p. ex. matériaux en feuilles, dalles ou panneaux caractérisés par des matériaux spécifiés en béton ou autre matériau analogue à la pierre en ciment d'amiante
Gear shift device (1) of a steering wheel group (500) of a vehicle operatively connected to a gearbox group configurable in an automatic shift mode and a manual shift mode. The gear shift device (1) comprises a paddle (10), pushable by the driver between an inactive position and an active position in which it commands a gear shift action of the gearbox group. The gear shift device (1) also comprising a control element (20) comprising a touch interface device (200) located on the paddle (10), suitable to be actuated by the driver to command a plurality of operating modes of the gearbox group.
An actuator (1) comprising a slide (10), a fixed frame (20), with respect to which the slide (10) is suitable to move, and control means (30) suitable to control said movement. Where the slide (10) has a box shape with, inside, at least one pair of helical elements (100) in a material selected from among the shape memory alloys. The helical elements (101, 102) have a first end (111, 112) operatively connected to the locking elements (200) of the frame (20), which extend transversely with respect to the slide.
F03G 7/06 - Mécanismes produisant une puissance mécanique, non prévus ailleurs ou utilisant une source d'énergie non prévue ailleurs utilisant la dilatation ou la contraction des corps produites par le chauffage, le refroidissement, l'humidification, le séchage ou par des phénomènes similaires
22.
ELECTRO-ACTIVE MACROCYCLIC OLIGOARENES AND OLIGOHETEROARENES WITH STEREOGENIC AXES
FONDAZIONE CASSA DI RISPARMIO DELLE PROVINCIE LOMBARDE (FONDAZIONE CARIPLO) (Italie)
Inventeur(s)
Sannicolo', Francesco Maria Enrico
Mussini, Patrizia Romana
Arnaboldi, Serena
Quartapelle Procopio, Elsa
Panigati, Monica
Martinazzo, Rocco
Selli, Elena
Chiarello, Gian Luca
Benincori, Tiziana
Longhi, Giovanna
Rizzo, Simona
Cirilli, Roberto
Penoni, Andrea
Abrégé
The present invention relates to electro-active, both achiral and chiral, polyconjugated macrocyclic oligoarene and oligoheteroarene compounds, optionally used as single enantiomers, and derivatives thereof, which are used in the manufacture of devices for the electronics field, the sensors field, the photovoltaics field, the chromatographic separation field or in stereoselective catalysis reactions.
C07D 295/096 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de carbone du cycle avec des radicaux hydrocarbonés substitués liés aux atomes d'azote du cycle substitués par des atomes d'oxygène ou de soufre liés par des liaisons simples avec les atomes d'azote du cycle et les atomes d'oxygène ou de soufre séparés par des carbocycles ou par des chaînes carbonées interrompues par des carbocycles
A61K 31/495 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec deux azote comme seuls hétéro-atomes d'un cycle, p. ex. pipérazine
C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
H01B 1/12 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisésEmploi de matériaux spécifiés comme conducteurs composés principalement d'autres substances non métalliques substances organiques
23.
MULTI-PARAMETRIC ENVIRONMENTAL DIAGNOSTICS AND MONITORING SENSOR NODE
The multi-parametric environmental diagnostics and monitoring sensor node (10) provides monitoring and diagnostics of a variety of different ambient environmental factors and is powered by multiple sources of renewable energy. The multi-parametric environmental diagnostics and monitoring sensor node (10) includes a base (38) and a plurality of environmental condition sensors (36a, 36b, 36c, 36d, 36e, 36f) mounted thereon. A controller (47) is also mounted on the base (38), the plurality of environmental condition sensors (36a, 36b, 36c, 36d, 36e, 36f) being in communication therewith. An external photovoltaic cell (18) is mounted to the base and an internal photovoltaic cell (34) is mounted in an opposed orientation on a cover (32). The external photovoltaic cell (18) and the internal photovoltaic cell (34) charge a power storage module (52), which powers the plurality of environmental condition sensors (36a, 36b, 36c, 36d, 36e, 36f) and the controller (47).
G01D 21/02 - Mesure de plusieurs variables par des moyens non couverts par une seule autre sous-classe
G01D 11/00 - Parties constitutives des dispositions pour la mesure qui ne sont pas spécialement adaptées à une variable particulière
G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
G01K 13/00 - Thermomètres spécialement adaptés à des fins spécifiques
G01W 1/11 - Dispositifs pour indiquer l'humidité de l'atmosphère
G01L 19/00 - Détails ou accessoires des appareils pour la mesure de la pression permanente ou quasi permanente d'un milieu fluent dans la mesure où ces détails ou accessoires ne sont pas particuliers à des types particuliers de manomètres
H02S 10/00 - Centrales électriques PVCombinaisons de systèmes d’énergie PV avec d’autres systèmes pour la production d’énergie électrique
H02N 10/00 - Moteurs électriques utilisant des effets thermiques
H02N 2/00 - Machines électriques en général utilisant l'effet piézo-électrique, l'électrostriction ou la magnétostriction
24.
UNIVERSITAS STUDIORUM BRIXIAE UNIVERSITY OF BRESCIA HEALTH & WEALTH
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Instructional and teaching material, books, manuals, booklets, publications and educational aids in paper form; Printed matter; Albums, photographs; Magazines; Newspapers; Booklets; Journals; Stationery. Provision of education, instruction, tuition and training; Information and consultancy in relation to education, training, instruction and teaching; Vocational retraining; Arranging and conducting of conferences, congresses, colloquiums, seminars and symposiums; colleges and Academies; Publishing, publication and loan of texts and books, information relating to education, teaching, organisation, management of conferences, congresses and seminars, including for training purposes. Scientific and technological services and research and design relating thereto; Industrial analysis and research services; Design and development of computer hardware and software; Chemical analysis; Computer system analysis; Material testing; Quality control; Chemical, cosmetological, biological, mechanical and scientific research; Industrial design; Clinical trials; Technical project studies; Research and development for others.
A waste treatment method for waste materials containing heavy metals, comprises mixing the fly ash, the fragmented waste material and an aqueous solution to obtain a homogenous colloidal mixture, and solidifying the colloidal mixture in an inert semi-finished product, wherein the heavy metal is entangled in an insoluble metal-silica compound. The solidifying step comprises a step of resting the colloidal mixture at a temperature below 40°C.
The invention deals with an aid device for reading a printed text, comprising a data acquisition peripheral with a camera and a communication interface, said peripheral being movable by a user on a printed text to frame a portion of text, a processing unit, communication means between the peripheral and the processing unit, and a vocal reproduction device. The processing unit is programmed to acquire a sequence of images framed by the camera, to detect when the user has stopped on the text, to recognise at least one word which the user intends reading, and to reproduce the sound of said at least one word by means of vocal synthesis by means of the vocal reproduction device.
The present invention relates to a pharmaceutical composition comprising at least one histone deacetylase inhibitor, and at least one sirtuin activator agent having the general formula described. Such composition is used as a medication to treat chronic neurodegenerative diseases, and/or in the treatment of tumours or neoplasms.
A61K 31/4406 - Pyridines non condenséesLeurs dérivés hydrogénés substituées uniquement en position 3, p. ex. zimeldine
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
The present invention relates to a method for the analysis of a sample by means of radiation, for example using X-ray techniques. The method comprises a first step of providing a substrate, for example a filter, having an substantially flat shape and comprising a first and a second main surface. The method further comprises a step of depositing an analyte on the substrate, for example a particulate, and a step of coating at least a first area comprising the analyte of at least one of the main surfaces with a layer or film, to obtain a sample at least partially coated. Such film is at least partially permeable to the radiation used in the analysis. Furthermore the method comprises a step of analysing the first coated area of the sample by means of the radiation passing through the film.