Hemostasis analyzers for medical purposes; Blood coagulation analyzers for medical purposes.
2.
NUCLEIC ACID MOLECULE ENCODING A CAR AND A VECTOR INCLUDING THE SAME, A CAR, AN IMMUNE CELL INCLUDING THE CAR AND A PHARMACEUTICAL COMPOSITION INCLUDING THE CELL, AND A METHOD FOR PRODUCING AN IMMUNE CELL INCLUDING THE CAR
The present invention relates to a nucleic acid molecule having a nucleotide sequence encoding a chimeric antigen receptor (CAR). The present invention relates to a vector including the nucleic acid molecule. The present invention relates to a CAR. The present invention relates to an immune cell including the CAR. The present invention relates to a pharmaceutical composition including the immune cell including the CAR. The present invention relates to a method for producing an immune cell including the CAR.
C07K 16/30 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire provenant de cellules de tumeurs
A61K 40/11 - Lymphocytes T, p. ex. lymphocytes infiltrant les tumeurs [TIL] ou lymphocytes T régulateurs [Treg]Cellules tueuses activées par les lymphokines [LAK]
C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
C12N 5/0783 - Cellules TCellules NKProgéniteurs de cellules T ou NK
Disclosed is a measurement apparatus for blood samples including a reagent storage unit for first and second containers storing a diluent and a hemolytic agent, respectively, and a transport unit arranged above it. A measurement unit, also above the storage unit, includes a third container for a staining solution, chambers for preparing first and second measurement samples, and detectors for electrical and optical signals. The apparatus is configured to process 300 to 500 samples per hour for measurement orders including complete blood count and five-part white blood cell differential counting. A supply unit provides reagents to the measurement unit, and a control unit manages the operations. The supply unit is configured to continue supplying the diluent and the hemolytic agent while the first or second container is being replaced, ensuring uninterrupted measurement.
G01N 33/49 - Analyse physique de matériau biologique de matériau biologique liquide de sang
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
Diagnostic apparatus for medical purposes used in medical laboratories; Blood testing apparatus; Apparatus for blood analysis; Medical diagnostic instruments for the analysis of body fluids; Hematology analyzers for medical diagnostic uses
5.
System for evaluation of inter-instrument difference
Disclosed is a sample analysis system comprising: a plurality of measurement units, each configured to measure a sample to obtain a measurement result based on a measurement order including one or more measurement items; an identification information reader configured to read identification information of each of a plurality of samples to be measured by at least one of the plurality of measurement units; and a computer that comprises a storage device configured to store the measurement results. The computer is configured to perform operations for an inter-instrument difference evaluation, the operations comprising: interrogating a storage device to identify a set of a plurality of measurement results obtained from a plurality of target measurement units, the set of the plurality of measurement results matching a condition for use in the inter-instrument difference evaluation; and generating evaluation information for the inter-instrument difference evaluation based on the set of the plurality of measurement results identified from the storage device.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
6.
System for evaluation of inter-instrument difference
Disclosed is a sample analysis system comprising: a plurality of measurement units, each configured to measure a sample to obtain a measurement result based on a measurement order including one or more measurement items; an identification information reader configured to read identification information of each of a plurality of first samples to be measured for diagnosis of a test subject by at least one of the plurality of measurement units; and a computer that is configured to: identify at least one of the plurality of first samples as a second sample used for a measurement for an inter-instrument difference evaluation, based on a timing to conduct the inter-instrument difference evaluation, wherein the timing is automatically determined by the computer; and control each of a plurality of target measurement units to measure the identified second sample based on a measurement order including one or more preset measurement items for the inter-instrument difference evaluation, and store a plurality of second measurement results of the second sample obtained from the plurality of target measurement units, for use in the inter-instrument difference evaluation, in the storage device in association with the identification information of the second sample.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
7.
SAMPLE ANALYZER, SAMPLE ANALYSIS SYSTEM, AND SAMPLE ANALYSIS METHOD
Disclosed is a sample analyzer comprising: a measurement unit configured to measure an analyte related to a dementia biomarker contained in a sample collected from a subject, the measurement unit comprising: a sample dispenser configured to aspirate the sample from a sample container and discharge the aspirated sample into a cuvette, a first reagent dispenser configured to aspirate a first reagent from a first reagent container and discharge the aspirated first reagent into the cuvette, wherein the first reagent immunologically reacts with the analyte, a second reagent dispenser configured to aspirate a second reagent from a second reagent container and discharge the aspirated second reagent into the cuvette, wherein the second reagent generates light corresponding to an amount of the reacted analyte, a detector configured to detect the generated light from a mixture of the sample, the first reagent, and the second reagent in the cuvette; a controller comprising a processor and programmed to obtain a measurement value of the analyte based on the light detected by the detector; a storage configured to store a reference value that specifies an outlier that may be caused by a factor other than dementia; and an output unit, wherein the controller is programmed to execute a determination on whether the measurement value is specified as the outlier based on the measurement value and the reference value, generate an analysis result of the dementia biomarker based on the measurement value and a result of the determination, and output the analysis result of the dementia biomarker via the output unit.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
8.
CELL ANALYSIS METHOD, TRAINING METHOD FOR DEEP LEARNING ALGORITHM, CELL ANALYZER, TRAINING APPARATUS FOR DEEP LEARNING ALGORITHM, CELL ANALYSIS PROGRAM, AND TRAINING PROGRAM FOR DEEP LEARNING ALGORITHM
The types of cells that cannot be determined by use of a conventional scattergram are determined. The problem is solved by a cell analysis method for analyzing cells contained in a biological sample, by using a deep learning algorithm having a neural network structure, the cell analysis method including: causing the cells to flow in a flow path; obtaining a signal strength of a signal regarding each of the individual cells passing through the flow path, and inputting, into the deep learning algorithm, numerical data corresponding to the obtained signal strength regarding each of the individual cells; and on the basis of a result outputted from the deep learning algorithm, determining, for each cell, a type of the cell for which the signal strength has been obtained.
G01N 33/487 - Analyse physique de matériau biologique de matériau biologique liquide
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
A specimen measurement system includes: a measurement unit configured to measure a specimen; and a control unit configured to analyze measurement data from the measurement unit. The measurement unit includes: a first reagent container accommodating a first reagent containing a substance that binds to an analyte in the specimen; a reagent holder configured to hold the first reagent container; a specimen processor configured to prepare a measurement sample by mixing the first reagent and the specimen; and a detector configured to interrogate the analyte for the measurement of the measurement sample. The measurement unit is arranged on a housing that stores a second reagent container, the second reagent container containing a second reagent used for at least one of: washing of a flow path of the measurement unit, dilution of the specimen, preparation of the measurement sample, and interrogation of the analyte of the measurement sample by the detector.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
This specimen measurement device for measuring a blood specimen collected from a subject includes: an electrical detection unit (120) for detecting an electrical signal corresponding to a cell; an optical detection unit (110) for detecting an optical signal corresponding to the cell; a hemoglobin detection unit (130) for detecting an optical signal corresponding to a blood pigment; a preparation unit (162); and an analysis unit for analyzing measurement data and providing an analysis result. The preparation unit (162) prepares a measurement sample PAB for detecting platelet aggregation by the optical detection unit (110) in accordance with a measurement order including a measurement instruction for a measurement item CBC or measurement items CBC and DIFF. The analysis unit analyzes measurement data obtained by measuring the measurement sample PAB, and provides an analysis result relating to platelet aggregation.
Medical diagnostic solution comprising one or more instruments for blood analysis and a transportation system to transport sample tubes; Medical diagnostic solution comprising one or more diagnostic analyzers for measuring, testing or analyzing blood and a transportation system to transport sample tubes; Hemostasis laboratory automation solutions and parts therefor comprising one or more medical diagnostic testing analyzers in the field of hemostasis
13.
IMAGE ANALYSIS METHOD, APPARATUS, NON-TRANSITORY COMPUTER READABLE MEDIUM, AND DEEP LEARNING ALGORITHM GENERATION METHOD
Disclosed is a cell analysis system including an imaging apparatus and an image analysis apparatus. The imaging apparatus includes a stage on which a smear preparation having a blood sample from a subject smeared thereon, a microscope configured to enlarge analysis target cells in the blood sample on the smear preparation, and a camera configured to capture enlarged images of the analysis target cells. The image analysis apparatus includes a processor and a memory storing a computer program. The computer program, when executed by the image analysis apparatus, causes the image analysis apparatus to generate analysis data from the image of the respective analysis target cells captured by the imaging apparatus, input the analysis data into a classifier having a neural network structure, and classify, by use of the classifier, the respective analysis target cells into one type of blood cell among a plural types of blood cells.
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p. ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersectionsAnalyse de connectivité, p. ex. de composantes connectées
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
Disclosed is a system for supporting health management of an athletic player, comprising: a measuring device configured to measure myoglobin contained in blood of the player; and a server configured to record an exercise load of the player and a measured value of the myoglobin of the player, wherein the server is configured to provide the exercise load of the player and the measured value of the player in response to a request from a terminal.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
15.
BLOOD ANALYZER, BLOOD ANALYZING METHOD, AND PROGRAM
A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a blood preparation; a measurement part that measures the measurement specimen; a measurement mode selection unit that receives an input of a type of blood preparation as a measurement target selected from a plurality of types of blood preparations; and a controller. The controller may cause the specimen preparation part to prepare the measurement specimen depending on the selected type of blood preparation.
G01N 33/49 - Analyse physique de matériau biologique de matériau biologique liquide de sang
G01N 33/487 - Analyse physique de matériau biologique de matériau biologique liquide
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
16.
SURGICAL IMAGE PROVIDING METHOD USING SURGICAL ROBOT, AND INFORMATION PROCESSING SYSTEM
Disclosed is a surgical image providing method using a surgical robot for providing an image of a surgery performed by the surgical robot, the surgical robot including an arm device to which a surgical instrument is attached, and an operation device that an operator operates to drive the arm device. The method includes: obtaining a state log indicating a state of an operation target of the operation device, the state being changed according to an operation of the operator to the operation target; generating a reconstructed image visualizing the operation of the operator to the operation target, on the basis of the state log; and providing a surgical image in which a motion image showing a motion of the surgical robot or the surgical instrument is associated with the reconstructed image.
A61B 17/29 - Pinces pour la chirurgie faiblement invasive
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
Disclosed is a sample measurement apparatus configured to measure a sample collected from a subject, comprising: a measurement unit configured to execute a measurement of the sample, the measurement including preparing a measurement sample from the sample and a reagent and detecting at least optical signals corresponding to cells in the measurement sample; and an analysis unit configured to analyze the cells at least according to the optical signals detected in the measurement of the sample by the measurement unit, wherein the measurement unit is operable to selectively perform a plurality of measurement operations including: (1) a first measurement operation that includes the measurement of the sample using a first reagent containing a first fluorescent dye that stains leukocytes for classification of leukocytes; (2) a second measurement operation that includes the measurement of the sample using a second reagent containing a second fluorescent dye that stains cells suspected of malaria infection; and (3) a third measurement operation that includes the measurement of the sample using the first reagent and the second reagent.
The present invention relates to a measurement device for analyzing cells, the measurement device comprising: an electric measurement unit that electrically measures cells; a first optical measurement unit that optically measures cells; a second optical measurement unit that optically measures hemoglobin; a sample preparation unit that mixes a first fluorescent dye and a second fluorescent dye with a specimen to prepare a measurement sample; and an analysis unit that provides a measurement result of the measurement sample. The first optical measurement unit measures an optical signal including at least one of a first fluorescent signal generated from the first fluorescent dye and a second fluorescent signal generated from the second fluorescent dye. The analysis unit refers to the optical signal and classifies cells by executing an analysis based on differences in staining characteristics and fluorescence characteristics of the fluorescent dyes.
The present invention relates to a measurement device for analyzing cells in a specimen, the measurement device comprising a chamber for preparing a measurement sample, a light source for irradiating cells with light, a detection unit that detects an optical signal, and an analysis unit that analyzes an optical signal. The detection unit detects an optical signal including at least one of a first fluorescent signal corresponding to a first fluorescent dye that binds to DNA and a second fluorescent signal corresponding to a second fluorescent dye that binds to RNA. The analysis unit determines whether the mechanism of leukocyte increase is neoplastic on the basis of at least the first fluorescent signal, and determines whether the mechanism of leukocyte increase is reactive on the basis of at least the second fluorescent signal. The present invention relates to a reagent used in the measurement device and a method for analyzing cells in a specimen.
Disclosed is a specimen analysis apparatus comprising: a measurement unit configured to acquire optical information of cells contained in a specimen by irradiating the cells with a plurality of diffracted lights generated by causing light to be incident on a diffractive optical element; and an analysis unit configured to analyze the optical information obtained by the measurement unit using an artificial intelligence algorithm to acquire first information on leukemic cells contained in the specimen.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
22.
METHOD OF GENERATING QUALITY CONTROL INFORMATION, APPARATUS FOR GENERATING QUALITY CONTROL INFORMATION, AND PROGRAM
A method of generating smear quality control information according to an embodiment may include: obtaining a plurality of image data from a plurality of smears, respectively; obtaining, from the plurality of image data, feature values each of which reflects a staining state of each smear; and generating quality control information based on the feature values.
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
G01N 15/02 - Recherche de la dimension ou de la distribution des dimensions des particules
G01N 15/10 - Recherche de particules individuelles
G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
G01N 15/1433 - Traitement du signal utilisant la reconnaissance d’image
G01N 33/96 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir un étalon de contrôle du sang ou du sérum
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G06T 7/90 - Détermination de caractéristiques de couleur
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Diagnostic reagents for medicinal use; Chemical reagents for medical use; Quality control reagents for medical diagnostic use; Calibration solutions for medical and veterinary diagnostic apparatus; Cleaning solutions for medical purposes.
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Downloadable middleware for software application integration; Downloadable middleware for the centralized monitoring, management, and optimization of clinical laboratory workflows; Downloadable middleware for providing an interface between clinical laboratory equipment and a centralized command center; Downloadable middleware for providing an interface between pre-analytical sample processing hardware, an automated sample transport track, and analytical instruments; Downloadable middleware for providing an interface between medical laboratory automation equipment and clinical diagnostic instruments; Downloadable software for laboratory automation and workflow management; Downloadable software for the centralized monitoring, management, and optimization of clinical laboratory workflows; Downloadable software for coordinating pre-analytical, analytical, and post-analytical specimen processing; Downloadable software for enabling communication between diagnostic analyzers and laboratory information systems; Downloadable software for providing a real-time laboratory operations dashboard software for tracking specimen status, instrument performance, quality control metrics, and workflow efficiency in clinical diagnostic laboratories; Downloadable software for conducting clinical in-vitro diagnostics; Downloadable software for interfacing with pre-analytical sample processing hardware, an automated sample transport track, and analytical instruments; Downloadable software for interfacing with medical laboratory automation equipment and clinical diagnostic instruments Providing temporary use of online non-downloadable middleware for providing an interface between clinical laboratory equipment and a centralized command center; Providing temporary use of online non-downloadable middleware for providing an interface between pre-analytical sample processing hardware, an automated sample transport track and analytical instruments; Providing temporary use of online non-downloadable middleware for providing an interface between medical laboratory automation equipment and clinical diagnostic instruments; Providing on-line non-downloadable software for the centralized monitoring, management, and optimization of clinical laboratory workflows; Providing on-line non-downloadable software for coordinating pre-analytical, analytical, and post-analytical specimen processing; Providing on-line non-downloadable software for enabling communication between diagnostic analyzers and laboratory information systems; Providing on-line non-downloadable software for providing a real-time laboratory operations dashboard software for tracking specimen status, instrument performance, quality control metrics, and workflow efficiency in clinical diagnostic laboratories; Providing on-line non-downloadable software for conducting clinical in-vitro diagnostics; Providing on-line non-downloadable software for interfacing with pre-analytical sample processing hardware, an automated sample transport track, and analytical instruments; Providing on-line non-downloadable software for interfacing with medical laboratory automation equipment and clinical diagnostic instruments; Software as a service (SAAS) services featuring software for laboratory automation and workflow management; Software as a service (SAAS) services featuring software for the centralized monitoring, management, and optimization of clinical laboratory workflows; Software as a service (SAAS) services featuring software for coordinating pre-analytical, analytical, and post-analytical specimen processing; Software as a service (SAAS) services featuring software for enabling communication between diagnostic analyzers and laboratory information systems; Software as a service (SAAS) services featuring software for providing a real-time laboratory operations dashboard software for use in clinical diagnostic laboratories; Software as a service (SAAS) services featuring software for conducting clinical in-vitro diagnostics; Software as a service (SAAS) services featuring software for interfacing with pre-analytical sample processing hardware, an automated sample transport track, and analytical instruments; Software as a service (SAAS) services featuring software for interfacing with medical laboratory automation equipment and clinical diagnostic instruments; Providing on-line non-downloadable software for laboratory automation and workflow management
25.
METHOD FOR CONTROLLING SPECIMEN ANALYSIS SYSTEM AND SPECIMEN ANALYSIS SYSTEM
A method for controlling a specimen analysis system including at least one measurement unit according to one or more embodiments is disclosed. The method may include automatically starting at least one measurement unit according to a schedule registered by a user, automatically supplying a quality control specimen to the measurement unit that is automatically started; and measuring the quality control specimen by the measurement unit.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G01N 1/44 - Traitement d'échantillons mettant en œuvre un rayonnement, p. ex. de la chaleur
G01N 33/96 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir un étalon de contrôle du sang ou du sérum
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
In a configuration for analyzing data of cells measured by a cell measuring apparatus, accuracy of cell classification is improved without requiring the cell measuring apparatus to have high information processing capability. A cell analysis method, using a cell analyzer for analyzing cells in accordance with an artificial intelligence algorithm, includes: obtaining the data regarding the cells measured by the cell measuring apparatus; analyzing the data to generate information regarding a cell type of each of the cells; and transmitting the information to the cell measuring apparatus.
A quality control method of a specimen analysis system is disclosed, including: receiving a setting of a quality control measurement condition from a user; determining at least one quality control specimen to be used for quality control measurement from among a plurality of the quality control specimens stored in a storage, according to the quality control measurement condition and information on the quality control specimens that are stored in the storage section; taking out the determined quality control specimen from the storage; transporting the determined quality control specimen to a measurement unit; and measuring the transported quality control specimen by the measurement unit.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G01N 1/44 - Traitement d'échantillons mettant en œuvre un rayonnement, p. ex. de la chaleur
G01N 33/96 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir un étalon de contrôle du sang ou du sérum
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
28.
DISEASE DIFFERENTIATION SUPPORT METHOD, DISEASE DIFFERENTIATION SUPPORT APPARATUS, AND DISEASE DIFFERENTIATION SUPPORT COMPUTER PROGRAM
Disclosed is a disease differentiation support method for supporting disease differentiation, the disease differentiation support method including: obtaining a first parameter obtained by analyzing an image including a cell contained in a sample collected from a subject; obtaining a second parameter regarding a number of cells contained in the sample; and generating, by using a computer algorithm, differentiation support information for supporting disease differentiation, on the basis of the first parameter and the second parameter.
G06N 20/20 - Techniques d’ensemble en apprentissage automatique
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Diagnostic reagents for medicinal use; Chemical reagents for medical use; Reagents for blood analysis for medical or veterinary purposes; Reagents for hematology analysis for medical or clinical use; Reagents for smear test sample making apparatus and instruments; Cleaning solutions for medical purposes; Buffer solutions for medical or veterinary use.
Medical analyzer for cancer lymph node metastasis detection; Intraoperative medical testing apparatus for lymph node metastasis diagnosis; Lymph node metastasis testing apparatus for intraoperatively collected tissue.
Hematology analyzers for medical diagnostic uses; Medical diagnostic instruments for the analysis of body fluids; Apparatus for blood analysis; Blood testing apparatus
Disclosed is a measurement apparatus for analyzing a cell contained in a specimen, comprising: a chamber for preparing a measurement sample in which the cell is stained with first and second fluorescent dyes contained in a reagent supplied from at least one reagent container; a liquid feeding section for feeding the reagent from the reagent container to the chamber via a liquid feeding tube provided between the reagent container and the chamber; and a detection section that acquires first and second signals each corresponding to fluorescence of a first wavelength and fluorescence of a second wavelength emitted from the cell stained with the first and second fluorescent dyes in response to irradiation of the measurement sample flowing in a flow cell with light; and an analysis section that analyzes the cell on the basis of the first and second signals.
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
G01N 15/10 - Recherche de particules individuelles
G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
G01N 21/75 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Diagnostic reagents for medicinal use; Reagents for urinalysis for medical or veterinary purposes; Medical or veterinary diagnostic reagents, namely, sheath solutions; diagnostic preparations, namely, Diluents for medical or medical clinical diagnostic use; Stains, namely, fluorescent dyes for medical purposes for urinalysis for medical or clinical diagnostic use
Even when there is no definite diagnosis, a disease status is assessed. A system operable to monitor one or more patients each suspected of having a disease based on a result of a test for assessing a condition of the patient, the system comprising: a disease determination part configured to analyze a database of measurement data collected in association with information regarding a location of the patient and to determine the patient suspected of having the disease, the measurement data acquired by a plurality of specimen measurement apparatuses running the test on a specimen of the patient; and a status monitor part configured to monitor a status of the disease in an area determined based on the information regarding the location.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
35.
METHOD FOR DETECTING TRANSTHYRETIN TETRAMER, AND METHOD FOR EVALUATING STABILITY
NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (Japon)
Inventeur(s)
Iino, Takuya
Murakami, Shun
Kobayashi, Yuto
Toh, Ryuji
Nagao, Manabu
Abrégé
An object of the invention is to provide a means capable of detecting transthyretin (TTR) tetramer in a sample. Provided is a method comprising forming a complex comprising the TTR tetramer in the sample, a compound capable of binding to the thyroxine binding site of the TTR tetramer, an antibody capable of binding to the TTR monomer, and a labeling substance, and measuring a signal generated by the labeling substance contained in the complex.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
Disclosed is an analysis system comprising: a blood cell analyzer configured to measure at least CBC items including white blood cell count, red blood cell count, hemoglobin amount, hematocrit value, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and platelet count; a blood coagulation analyzer; and a transporter having a transport path configured to transport a sample to a first acquisition position on which the sample is acquired by the blood cell analyzer and a second acquisition position on which the sample is acquired by the blood coagulation analyzer, wherein the blood cell analyzer, the blood coagulation analyzer, and the transporter are arranged in positions and orientations that allow accesses from at least one position along one side of the transport path.
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
Disclosed is an analysis system comprising: a blood cell analyzer configured to measure at least CBC items including white blood cell count, red blood cell count, hemoglobin amount, hematocrit value, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and platelet count; a blood coagulation analyzer; and a transporter configured to transport a sample to a first acquisition position on which the sample is acquired by the blood cell analyzer and a second acquisition position on which the sample is acquired by the blood coagulation analyzer, the transporter having a first side and a second side opposite to the first side, wherein the blood cell analyzer and the blood coagulation analyzer are arranged along the first side of the transporter, and the blood cell analyzer, the blood coagulation analyzer, and the transporter are arranged in positions and orientations that allow accesses from the second side of the transporter.
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Diagnostic reagents for medicinal use; Reagents for urinalysis for medical or veterinary purposes; Medical or veterinary diagnostic reagents, namely sheath solutions; Diluents for medical or clinical diagnostic use; Stains for urinalysis for medical or clinical diagnostic use; Control materials for quality control for medical use; Calibrating solutions for calibrating clinical testing apparatus for medical or veterinary purposes; Cleaning solutions for medical purposes.
Clinical laboratory analyzers of blood, namely, apparatus for blood analysis for medical purposes; Blood testing apparatus; Apparatus for blood analysis for medical purposes
40.
INFORMATION SYSTEM, AN INFORMATION PROCESSING DEVICE, AND A NON-TRANSITORY COMPUTER-READABLE MEDIUM
Disclosed in an information system configured to exchange information about a patient among a plurality of health professionals including: an information processing device; and a plurality of terminals operated by the health professionals, wherein the information processing device is configured to execute operations, the operations including: receiving, from one of the terminals, a request of creating a group based on at least one of: (i) first information identifying the patient to whom medicine is provided and (ii) second information identifying a specialty of the medicine, searching for a health professional satisfying the request, creating a group of health professionals, the group including a health professional who operated the one terminal from which the request is sent and at least one health professional satisfying the request, and transmitting information about the patient, among the terminals, operated by the health professionals included in the group, to at least one second terminal.
G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p. ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
A sample analyzer for analyzing cells in a sample collected from a subject according to one or more embodiment may include a first measurement unit configured to interrogate cells passing through at least one beam spot of a first illumination light to obtain first light information, a second measurement unit configured to interrogate cells passing through an irradiation area of a second illumination light to obtain second light information, wherein the second illumination light includes a plurality of distributed lights generated by diffracting a light using a diffractive optical element, and a controller configured to generate a cell analysis result based on one of (1) a first analysis result based on the first light information, (2) a second analysis result based on the second light information, and (3) the first analysis result and the second analysis result.
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
G01N 15/10 - Recherche de particules individuelles
G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
Medical apparatus for performing in-vitro diagnostic tests; Clinical laboratory analyzers of blood for medical purposes; Blood testing apparatus; Apparatus for blood analysis for medical purposes.
43.
METHOD FOR PREPARING QUALITY ASSURANCE AND QUALITY CONTROL REPORT ON MICROBIAL PRODUCTION PROCESS
This invention is to provide rapid microbiological test reports, using microbiological testing devices, such as fluorescent flow cytometry (FCM), fluorescent microscopy, and polymerase chain reaction (PCR), HPC, etc., to create a true and comprehensive microbiological description of each step of microbial production process in real-time. These microbiological descriptions are combined to create a unique baseline microbiological description or “Fingerprint” of the entire process.
C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p. ex. fermenteurs commandés automatiquement
Disclosed is a data sharing system configured to share health data of a patient between (i) a plurality of types of applications configured to acquire the health data and (ii) a terminal of a medical institution, the data sharing system comprising: a data storage configured to store, in association with at least one of the applications, a linkage between a first account ID which allows the patient to access the data sharing system and a second account ID which allows a user of the terminal of the medical institution to access the data sharing system; and a controller programmed to identify, in response to a request from the terminal of the medical institution, the health data acquired by the at least one application associated with the linkage between the first account ID and the second account ID.
G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p. ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
A method for analyzing a urine sample capable of discriminating red blood cells in a specimen with higher accuracy, and a reagent for analyzing a urine sample are provided. The method includes obtaining a measurement sample comprising: the urine sample; at least one compound selected from the group consisting of aliphatic compound and aromatic compound; and a fluorescent dye that stains nucleic acids or cytoplasm; irradiating the measurement sample with light and obtaining fluorescence information of particles contained in the measurement sample; and detecting red blood cells based on the fluorescence information, wherein the aliphatic compound is at least one selected from the group consisting of 1,2-alkanediol having 8 to 10 carbon atoms and 2-alkanol having 7 to 9 carbon atoms, and the aromatic compound is chlorphenesin, 3-phenoxy-1-propanol, 1-(3-methoxyphenoxy)-2-propanol or orthophenylphenol.
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
46.
METHOD FOR MEASURING ACTIVITY OR CONCENTRATION OF ALKALINE PHOSPHATASE CONTAINED IN EXTRACELLULAR VESICLE IN SAMPLE, POLYPEPTIDE MOLECULE, METHOD FOR PRODUCING THE SAME, AND CALIBRATOR
To provide a calibrator used for measuring activity or concentration of alkaline phosphatase contained in an extracellular vesicle in a sample, and a measurement method using the calibrator. To solve the above problem, by acquiring an activity value or concentration of alkaline phosphatase contained in an extracellular vesicle in a sample using a calibrator containing a polypeptide molecule having a series of amino acid sequences including an amino acid sequence of alkaline phosphatase and an amino acid sequence of a membrane protein present on a surface of the extracellular vesicle.
G01N 33/573 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour enzymes ou isoenzymes
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
C12N 9/16 - Hydrolases (3.) agissant sur les liaisons esters (3.1)
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
47.
MONOCLONAL ANTIBODY, REAGENT FOR MEASURING CRTAC1B, REAGENT KIT, AND METHOD FOR MEASURING CRTAC1B
Public University Corporation Yokohama City University (Japon)
Inventeur(s)
Suganuma, Masatoshi
Kubo, Hiroyuki
Takei, Kohtaro
Takahashi, Keita
Abrégé
An object of the present invention to provide a monoclonal antibody that specifically binds to Crtac1B and/or a fragment thereof, a reagent and a reagent kit for measuring Crtac1B containing the antibody, and a method for measuring Crtac1B using the antibody. The present invention provides an isolated monoclonal antibody, wherein the heavy chain including a CDR1 including the amino acid sequence of SEQ ID NO: 1, a CDR2 including the amino acid sequence of SEQ ID NO: 2, and a CDR3 including the amino acid sequence of SEQ ID NO: 3, and the light chain comprises a CDR1 including the amino acid sequence of SEQ ID NO: 4, a CDR2 including the amino acid sequence KAS, and a CDR3 comprising the amino acid sequence of SEQ ID NO: 5.
C07K 16/18 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
G01N 33/577 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet faisant intervenir des anticorps monoclonaux
48.
SAMPLE ANALYSIS SYSTEM, CONSUMABLE MANAGER, AND CONSUMABLE MANAGEMENT METHOD
Disclosed is a sample analysis system comprising a plurality of sample analyzers configured to analyze samples by using consumables, and a consumable manager configured to manage a replacement timing of the consumables in each of the sample analyzers, wherein the consumable manager comprises a controller, a storage, and an interface for an input and an output of information, wherein the controller is configured to obtain a usage record of the consumables from each of the sample analyzers and store the usage record in the storage, receive, via the interface, an input specifying a desired period among multiple periods of different lengths of time including (i) a period longer than a day and (ii) a period of a day or shorter, and provide, via the interface, information regarding a predicted replacement timing of the consumables during the desired period based on the usage record.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
Disclosed is a specimen measurement apparatus including a measurement unit configured to measure a specimen, the specimen measurement apparatus including: control software configured to control the measurement unit; data management software configured to manage data regarding the measurement unit that operates under control by the control software; and an interface configured to allow application software capable of being added to a system including the specimen measurement apparatus, to utilize the data, wherein a function of the system is expanded by the application software added to the system.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G01N 1/38 - Dilution, dispersion ou mélange des échantillons
G01N 21/00 - Recherche ou analyse des matériaux par l'utilisation de moyens optiques, c.-à-d. en utilisant des ondes submillimétriques, de la lumière infrarouge, visible ou ultraviolette
G01N 27/00 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques
Disclosed is a data management system configured to manage data regarding a specimen measurement system including a measurement unit configured to measure a specimen and control software configured to control the measurement unit, the data management system including: data management software configured to manage data regarding the measurement unit that operates under control by the control software; and an interface configured to allow application software capable of being added to the specimen measurement system, to utilize the data, wherein a function of the specimen measurement system is expanded by the application software added to the specimen measurement system.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
Disclosed is a system including a measurement unit configured to measure a specimen, the system including: control software configured to control the measurement unit; data management software configured to manage data regarding the measurement unit that operates under control by the control software; and an interface configured to allow application software capable of being added to the system, to utilize the data, wherein a function of the system is expanded by the application software added to the system.
Disclosed is a smearing apparatus including a printer configured to print the machine-readable code on the slide glass to achieve both the continuation of smear specimen preparation and the identification of the slide glass. The smearing apparatus obtains, by the controller of the smearing apparatus, information regarding an availability of the machine-readable code printed by the printer, and performs, by the controller, a first control of printing the machine-readable code on the slide glass by the printer, or a second control different from the first control.
G06K 15/02 - Dispositions pour produire une présentation visuelle permanente des données de sortie utilisant des imprimantes
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G02B 21/34 - Lames de microscope, p. ex. montage d'échantillons sur des lames de microscope
G06K 15/00 - Dispositions pour produire une présentation visuelle permanente des données de sortie
53.
SAMPLE MEASUREMENT APPARATUS AND SAMPLE MEASUREMENT METHOD
A sample measurement apparatus according to an embodiment may be a sample measurement apparatus for measuring a platelet aggregation function of a blood sample. The apparatus may include: a detector configured to measure optical information of platelet-rich plasma and platelet-poor plasma prepared from the blood sample; a controller configured, based on the optical information of the platelet-rich plasma and the platelet-poor plasma, to acquire information regarding the platelet aggregation function of the blood sample; and a display configured to display the information regarding the platelet aggregation function. The controller is configured to obtain, based on measurement result of the platelet-rich plasma by the detector, evaluation information regarding adequacy of the platelet-rich plasma as a specimen, and display the evaluation information on the display.
G01N 33/86 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir le temps de coagulation du sang
G01N 1/28 - Préparation d'échantillons pour l'analyse
G01N 21/17 - Systèmes dans lesquels la lumière incidente est modifiée suivant les propriétés du matériau examiné
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Diagnostic reagents for medical research Nucleic acids for pharmaceutical, medical or veterinary use; chemical reagents for medical or veterinary purposes; diagnostic reagents and diagnostic preparations for medical use; diagnostic reagents for clinical use; reagents for genetic testing for medical use
To provide a sample analysis method and a sample analysis system that can efficiently provide reliable assay results using a plurality of analyzer with different measurement methods. The sample analysis method for analyzing a sample using a plurality of analyzer (urine qualitative analyzer 10, urine particle analyzer 20 and imaging analyzer 30) the measuring method differs from each other includes a step of measuring a sample by the first analyzer, based on the first measurement result that varies according to the amount of analyte in the sample, and a step of determining the measurement conditions by the second analyzer.
G01N 33/72 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir les pigments du sang, p. ex. l'hémoglobine, la bilirubine
G01N 1/14 - Dispositifs d'aspiration, p. ex. pompesDispositifs d'éjection
G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur
56.
INFORMATION EXCHANGE METHOD, PROGRAM, AND INFORMATION SYSTEM
Disclosed is an information system configured to exchange information about a patient among a plurality of health professionals, including: an information processing device; and a terminal of each of the health professionals, wherein the information processing device is configured to execute operations including: receiving a group creation request based on one of patient identification information and specialty attribute information, searching for a health professional satisfying the group creation request, creating a group including a health professional having made the group creation request and one of a health professional in charge of the patient and a health professional having the specialty, outputs template data corresponding to the group, and transmitting information about the patient to an input item of the template data in the terminal of one of the health professionals in the group, the information being transmitted to the terminal of another one of the health professionals in the group.
G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p. ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
57.
METHOD FOR CONTROLLING SPECIMEN ANALYSIS SYSTEM AND SPECIMEN ANALYSIS SYSTEM
A method and system for controlling a specimen analysis system including at least one measurement unit according to one or more embodiments is disclosed. The method may include automatically starting at least one measurement unit according to a schedule registered by a user; automatically supplying a quality control specimen to the measurement unit that is automatically started; and measuring the quality control specimen by the measurement unit.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G01N 1/44 - Traitement d'échantillons mettant en œuvre un rayonnement, p. ex. de la chaleur
G01N 33/96 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir un étalon de contrôle du sang ou du sérum
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
37 - Services de construction; extraction minière; installation et réparation
Produits et services
(Based on 44(e))(Based on Intent to Use) Maintenance and repair of medical analyzers and peripheral instruments in the field of in vitro diagnostics; Maintenance and repair of apparatus and instruments for clinical laboratory tests; Remote monitoring of the functioning and use of electrical equipment, namely, medical analyzers and peripheral instruments used in in vitro diagnostics; Provision of information relating to maintenance and repair of medical analyzers and peripheral instruments in the field of in vitro diagnostics; Provision of information relating to maintenance and repair of apparatus and instruments for clinical laboratory tests; Technical support services, namely, troubleshooting in the nature of repair of medical analyzers and peripheral instruments in the field of in vitro diagnostics
59.
IMAGE ANALYSIS METHOD, APPARATUS, NON-TRANSITORY COMPUTER READABLE MEDIUM, AND DEEP LEARNING ALGORITHM GENERATION METHOD
Disclosed is an image analysis method including inputting analysis data into a classifier having a neural network structure, the analysis data being generated from an image of an analysis target cell and including information regarding the analysis target cell; and classifying, by use of the classifier, the analysis target cell into at least one of categories of a blood cell. The categories include morphological features of white blood cells. The morphological features of white blood cells include at least morphological nucleus abnormality, presence of vacuole, granule morphological abnormality, granule distribution abnormality, presence of abnormal granule, cell size abnormality, presence of inclusion body, or bare nucleus.
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p. ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersectionsAnalyse de connectivité, p. ex. de composantes connectées
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
60.
METHOD OF TRANSPORTING RACK AND SAMPLE MEASUREMENT SYSTEM
A sample measurement system according to an embodiment may include: sample measurement units that receive supply of containers and perform measurement on samples; a rack setting unit in which a rack storing the containers to be supplied to at least one of the sample measurement units is set; a first transport path that transports the containers from the rack setting unit to at least one of the sample measurement units; a second transport path that is provided at a position different from the first transport path in a height direction and that transports the containers from at least one of the sample measurement units to the rack setting unit; and a transfer path that transfers the containers between the first transport path and the second transport path.
B01L 9/00 - Dispositifs de supportDispositifs de serrage
B01L 9/06 - Supports de tubes à essaiPorte-tubes à essai
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
Disclosed is a solid-phase carrier used for measuring an analyte, comprising: a substrate; and a nanostructured material disposed on one surface of the substrate, wherein the nanostructured material comprises: a plasmon excitation layer formed of a material capable of exciting surface plasmon resonance and having a nanostructure in which localized surface plasmon resonance is excited by irradiation of light; and a coating layer formed of a material that does not excite surface plasmon resonance, wherein the plasmon excitation layer includes a coated region covered by the coating layer and an uncoated region not covered by the coating layer, wherein the uncoated region includes a hotspot where localized surface plasmon resonance occurs, and wherein a surface of the coating layer has a lower binding affinity for a specific binding substance of the analyte than a surface of the plasmon excitation layer.
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
Methods and systems are disclosed for generating accurate reportable test result counts for client billing purposes. In one approach, a method includes receiving, via network, a plurality of test results from at least one sample analyzer of each of a plurality of customers, selecting test results from the plurality of test results based on a plurality of determination rules adaptable to each of the customers, and determining, for each of the customers, a number of the selected test results for billings to each of the customers. Systems capable of performing the above method and other methods are likewise disclosed.
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p. ex. leur création ou leur transmission
G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic reagents for medicinal use; medical diagnostic reagents for blood analysis; stain solutions for hematology analysis for medical or medical diagnostic purposes Medical apparatus for performing in-vitro diagnostic tests; medical or veterinary diagnostic apparatus and instruments for blood analysis; blood testing apparatus
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
Produits et services
Diagnostic reagents for medicinal use; Medical diagnostic reagents for blood analysis; Stain solutions for hematology analysis for medical or medical diagnostic purposes. Diagnostic apparatus and instruments for medical purposes; Medical apparatus for performing in-vitro diagnostic tests; Medical or veterinary diagnostic apparatus and instruments for blood analysis; Blood testing apparatus.
66.
SPECIMEN MEASUREMENT APPARATUS AND SPECIMEN MEASUREMENT METHOD
Disclosed is a specimen measurement apparatus configured to measure a specimen, including: a housing; a first rack tray configured to store therein a rack capable of holding a plurality of specimen containers, the first rack tray being able to be taken in and out with respect to the housing; a second rack tray configured to store therein a rack capable of holding a plurality of specimen containers, the second rack tray being able to be taken in and out with respect to the housing, independently from the first rack tray; and a controller programmed to perform a process related to measurement of the specimen, according to a normal mode or an urgent mode that is set as specimen measurement mode for each of the racks, the urgent mode being higher in urgency in measurement than the normal mode. When a rack in the normal mode and a rack in the urgent mode are stored in the housing, the controller preferentially performs measurement of the specimen held in the rack in the urgent mode.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Reference control reagents for medical use for blood cell counters; hematology control materials for testing and calibrating blood cell counters for medical use and reagents, namely, blood and blood cells; hematology control materials for medical use for blood cell counters, namely, blood and blood cells; control reagents for quality control for medical purposes for blood cell counters; control blood for quality control of clinical testing for blood cell counters for medical or veterinary purposes
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Reference control reagents for medical use; Hematology control materials for testing and calibrating medical apparatus and reagents; Hematology control materials for medical use; Control reagents for quality control for medical purposes; Control blood for quality control of clinical testing apparatus for medical or veterinary purposes.
69.
LIQUID TRANSPORTING METHOD, DIGITAL ASSAY METHOD, AND DIGITAL ASSAY APPARATUS
The method according to an embodiment may be a method of transporting a liquid to a device in which a plurality of microwells formed on a substrate. The method may include: forming, in advance, at a position different from the device, a multiphase plug in which a solution for filling the plurality of microwells and an immiscible liquid that is immiscible with the solution for sealing the plurality of microwells filled with the solution are arranged in that order from a front in a flow direction; and transporting the multiphase plug to the device.
A solution replacement method according to an embodiment may be a solution replacement method of replacing a solution in a plurality of microwells formed on a substrate. The method may include: replacing an immiscible liquid that is immiscible to a first solution and seals the plurality of microwells that are filled with the first solution, with a gas; and filling the plurality of microwells with a second solution by introducing the second solution onto the substrate on which the immiscible liquid has been replaced with the gas.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
Provided is a computer-implemented method for testing blood of a subject, comprising: obtaining a plurality of haematological parameters for the blood; performing a plausibility check of haematological parameters; and outputting an indication of a determined probability of an infectious response of the subject based on parameters according to a result of the plausibility check.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
Disclosed is a sample analyzer including: an imaging part configured to image a test strip; a controller programmed to analyze a test strip image obtained through imaging; a display part configured to display an image analysis result of the test strip image; and an input part configured to receive an input of a predetermined instruction, wherein the controller is programmed to cause the display part to display a plurality of the test strip images selected by the input part.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
73.
SAMPLE ANALYZER AND METHOD FOR DETERMINING DIRT ON PLACEMENT PART INCLUDED IN SAMPLE ANALYZER
Disclosed is a sample analyzer configured to image a test strip and analyze an image of the test strip, to analyze a sample, the sample analyzer including: a transport part having a placement part on which the test strip is placed, the transport part being configured to move the placement part to an imaging position for the test strip; a controller programmed to analyze the image of the test strip obtained through imaging; and an imaging part configured to be able to image the placement part, wherein the controller is programmed to analyze an image of the placement part obtained through imaging, to detect dirt on the placement part.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
Disclosed is an analyzer configured to analyze a specimen, including: first and second sample preparation parts configured to prepare a first measurement sample from the specimen by using a first reagent; a third sample preparation part configured to prepare a second measurement sample from the specimen by using a second reagent; an optical measurement part configured to measure the first measurement sample to obtain an optical signal corresponding to white blood cells; an electric measurement part configured to measure the second measurement sample to obtain an electric signal corresponding to red blood cells; an analysis part configured to analyze the specimen, based on the optical signal and the electric signal; and a controller. The controller, according to a plurality of measurement orders, controls sample preparation in the first and second sample preparation parts and sample measurement by the optical measurement part such that at least a part of a period including preparation of the first measurement sample by the first sample preparation part, and measurement, by the optical measurement part, of the first measurement sample prepared in the first sample preparation part, overlaps with at least a part of a period including preparation of the first measurement sample by the second sample preparation part, and measurement, by the optical measurement part, of the first measurement sample prepared in the second sample preparation part.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G01N 33/80 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir les groupes ou les types sanguins
A specimen analyzer including: a measurement part configured to apply light to a measurement sample and a fluorescent dye that stains white blood cells contained in the blood specimen, detect fluorescence from the white blood cells contained in the measurement sample to which the light has been applied, and measure fluorescence signals on the basis of the detected fluorescence; an information processing part configured to generate, on the basis of the fluorescence signals, information about a distribution width of fluorescence intensities regarding a population of neutrophils contained in the measurement sample, and determine information about a degree of severity of an organ dysfunction due to an infection on the basis of the information about the distribution width of the fluorescence intensities regarding the population of neutrophils; and an output part configured to output the information about the degree of severity of the organ dysfunction due to the infection.
A general-purpose flow cytometer capable for using a plurality of combinations of fluorescent-labeled antibodies is provided. The flow cytometer includes a flow cell to flow therein a measurement sample prepared from a sample and a labeling reagent; light sources configured to irradiate with light; light receiving elements including first and second light receiving elements, the first light receiving element receiving first fluorescence from the particles that are labeled with a first fluorescent-labeled antibody and the second light receiving element receiving second fluorescence from the particles that are labeled with a second fluorescent-labeled antibody; and a storage configured to store a measurement condition associated with a measurement item corresponding to a predetermined combination of the fluorescent-labeled antibodies among the plurality of combinations of the fluorescent-labeled antibodies; and a processor programmed to execute operations in response to receiving instruction of measurement of identified measurement item.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
77.
ANALYSIS METHOD, INFORMATION PROCESSING APPARATUS, AND NON-TRANSITORY COMPUTER READABLE MEDIUM
Disclosed is an analysis method for analyzing a nucleic acid sequence of a sample by using a computer, the analysis method including detecting a predetermined mutation on the basis of sequence information having been read from the nucleic acid sequence; and creating, in accordance with a disease that corresponds to the sample, a report that includes information related to efficacy of a predetermined drug that corresponds to the predetermined mutation.
G16B 30/00 - TIC spécialement adaptées à l’analyse de séquences impliquant des nucléotides ou des aminoacides
C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
C12Q 1/6827 - Tests d’hybridation pour la détection de mutation ou de polymorphisme
G16B 25/00 - TIC spécialement adaptées à l’hybridationTIC spécialement adaptées à l’expression de gènes ou de protéines
G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p. ex. leur création ou leur transmission
78.
NUCLEIC ACID MOLECULE ENCODING CAR AND VECTOR COMPRISING THE SAME, IMMUNE CELL INCLUDING CAR AND PHARMACEUTICAL COMPOSITION COMPRISING THE CELL, METHOD FOR IMPROVING CYTOTOXIC ACTIVITY, AND METHOD FOR PRODUCING IMMUNE CELL INCLUDING CAR
A nucleic acid molecule having a nucleotide sequence encoding a chimeric antigen receptor, where the nucleic acid molecule includes a segment encoding an extracellular domain, a segment encoding a transmembrane domain, and a segment encoding an intracellular domain. The segment encoding the extracellular domain includes a nucleotide sequence encoding an antigen binding region including a light chain variable region and a heavy chain variable region, and at least three codons in a nucleotide sequence encoding framework region 3 of the light chain variable region as defined by the Chothia method are codons encoding acidic amino acid residues.
C07K 16/30 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire provenant de cellules de tumeurs
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
C12N 5/0783 - Cellules TCellules NKProgéniteurs de cellules T ou NK
79.
METHOD OF SURGICAL INSTRUMENT MANAGEMENT AND INFORMATION MANAGEMENT SYSTEM
In a method of managing surgical instruments that are used in surgical robotic systems installed in each of facilities, that are collected, for each of which a maintenance comprising at least cleaning and sterilization is performed, and that are shipped to any one of the facilities, the method according to one or more embodiments may include storing, for each of the surgical instruments, status information regarding status of the surgical instruments in association with identification information for each of the surgical instruments, and updating the status information corresponding to a surgical instrument that has been made available for shipping by the maintenance to the status information indicating that the surgical instrument is available to be selected for shipping to any one of the facilities.
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p. ex. pour planifier la maintenance ou les mises à jour
Disclosed is a compound represented by formula (1) or a salt thereof:
Disclosed is a compound represented by formula (1) or a salt thereof:
(wherein “Base” represents an aromatic heterocyclic group which may have a substituent, or an aromatic hydrocarbon ring group which may have a substituent; X1 represents a hydrogen atom, an alkyl group which may have a substituent, an alkenyl group which may have a substituent, an alkynyl group which may have a substituent, a cycloalkyl group which may have a substituent, or an aryl group which may have a substituent; X2 represents a hydrogen atom or —OR7; R1 to R7 and Z1 and Z2 each represent an atom or a group disclosed in the specification).
C07H 21/00 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques
C12Q 1/6876 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes
81.
Bst DNA POLYMERASE, REAGENT COMPOSITION, AND NUCLEIC ACID AMPLIFICATION METHOD
Disclosed is a Bst DNA polymerase comprising: (1) an amino acid sequence set forth in SEQ ID NO: 1, or (2) an amino acid sequence comprising a consensus sequence Asn-X-(Ser/Thr) (X is any amino acid residue other than a proline residue), and comprising an amino acid sequence having 80% or more identity to the amino acid sequence set forth in SEQ ID NO: 1, and having 5′ to 3′ DNA polymerase activity and strand displacement activity, wherein the consensus sequence comprises an N-linked sugar chain, and the N-linked sugar chain comprises three or more mannose residues.
Disclosed is a method for evaluating cell differentiation state, including inducing pluripotent stem cells to differentiate into mesodermal cells in a liquid medium by a first differentiation treatment for inducing pluripotent stem cells to differentiate into mesodermal cells and a second differentiation treatment for inducing the mesodermal cells to differentiate into cardiomyocytes; collecting a supernatant of the liquid medium comprising cells induced to differentiate by the second differentiation treatment; and measuring miRNA-3p in miR-1/133a cluster in the supernatant, where the miRNA-3p is at least one selected from a group consisting of miR-1-3p and miR-133a-3p, and the measured value of miRNA-3p is an index of differentiation into cardiomyocytes.
C12Q 1/6881 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour le typage de tissu ou de cellule, p. ex. sondes d’antigène leucocytaire humain [HLA]
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
83.
SAMPLE MEASUREMENT SYSTEM AND REAGENT SUPPLY APPARATUS
A sample measurement system includes sample measurement devices that measures samples using a first reagent and a second reagent, and a reagent supply apparatus, which includes a first piping connected to reagent containers of a first reagent container group, a first reagent reservoir that stores the first reagent transferred through the first piping, a second piping connected to reagent containers of a second reagent container group, and a second reagent reservoir that stores the second reagent transferred through the second piping. The first reagent stored in the first reagent reservoir is supplied to each of the sample measurement devices. The second reagent stored in the second reagent reservoir is supplied to each of the sample measurement devices.
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
84.
METHOD FOR ANALYZING BLOOD CELLS AND REAGENT FOR BLOOD CELL ANALYSIS
A method for analyzing blood cells includes acquiring first scattered light information, second scattered light information, and fluorescence information generated by irradiating a measurement sample that contains a particle stained with a fluorescent dye with a light of a first wavelength and a light of a second wavelength. The method includes identifying blood cells other than white blood cell from the particles in the measurement sample, with reference to the first scattered light information and the second scattered light information, and/or with reference to the first scattered light information and the fluorescence information. The method includes classifying the blood cells other than white blood cell into reticulocyte and platelet, with reference to the fluorescence information and the second scattered light information The first wavelength can be 315 nm or longer and 600 nm or shorter, and the second wavelength can be 610 nm or longer and 750 nm or shorter.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
G01N 15/10 - Recherche de particules individuelles
G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
85.
METHOD FOR ANALYZING BLOOD CELLS, REAGENT FOR BLOOD CELL ANALYSIS, REAGENT KIT FOR BLOOD CELL ANALYSIS, AND METHOD FOR FLUORESCENTLY STAINING BLOOD CELLS
Disclosed is a method for analyzing blood cells. The method includes irradiating a measurement sample that contains particles stained with a fluorescent dye with at least one light, to acquire fluorescence information and scattered light information generated from the particle. The method includes classifying blood cells from the particles in the measurement sample, with reference to the fluorescence information and the scattered light information. The fluorescent dye including a halogen, an alkyl group, sulfo group, and/or a benzyl group.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
Disclosed is a method for detecting platelet aggregation. The method includes acquiring first scattered light information and second scattered light information generated by irradiating a measurement sample that contains particles with a light of a first wavelength and a light of a second wavelength. The method includes acquiring information that indicates presence or absence of platelet aggregation, with reference to the first scattered light information and the second scattered light information. The first wavelength can be 315 nm or longer and 600 nm or shorter, and the second wavelength can be 610 nm or longer and 750 nm or shorter.
G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
G01N 15/10 - Recherche de particules individuelles
A method for communicating information related to a diagnostic analyzer includes receiving user identification information from a portable computer. A user associated with the user identification information operates the diagnostic analyzer. First diagnostic analyzer information is retrieved from at least one database that relates analyzer information to the user of the diagnostic analyzer. The first diagnostic analyzer information is related to the diagnostic analyzer. The first diagnostic analyzer information is communicated to the portable computer. Second diagnostic analyzer information from the diagnostic analyzer is retrieved. The second diagnostic analyzer information is generated by the diagnostic analyzer. The first and the second diagnostic analyzer information is communicated to the portable computer. The portable computer is configured to display the first and the second diagnostic analyzer related information.
G06Q 10/20 - Administration de la réparation ou de la maintenance des produits
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
Disclosed is a method for displaying a result of analysis performed on a specimen containing formed components. The method includes: obtaining, from each of the formed components, measurement values of at least three parameters; displaying a screen including a three-dimensional distribution chart in which the three parameters are used as axes and the formed components are represented by dots; and hiding specific dots on the three-dimensional distribution chart or changing a display format of the specific dots, according to an operation performed by a user.
G06T 11/20 - Traçage à partir d'éléments de base, p. ex. de lignes ou de cercles
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
G06F 3/0482 - Interaction avec des listes d’éléments sélectionnables, p. ex. des menus
G06F 3/04847 - Techniques d’interaction pour la commande des valeurs des paramètres, p. ex. interaction avec des règles ou des cadrans
G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie
90.
ASSESSMENT DEVICE, ASSESSMENT METHOD, AND COMPUTER-READABLE STORAGE MEDIUM
An assessment device includes: a display control unit configured to display unit images including at least one of an object having specificity and an object having sensitivity on a display unit in different tasks; a region setting unit configured to set, for each task, an object determination region corresponding to each object and an entire determination region corresponding to an entirety of the display unit; a determining unit configured to determine whether a gaze point of a subject is present in each object determination region and the entire determination region based on a detected position of the gaze point; an arithmetic unit configured to calculate an object gaze rate and an entire gaze rate based on a determination result of the determining unit; and an assessing unit configured to calculate a score based on the rates, and acquire assessment data based on the calculated score.
Disclosed is a management method for an analyzer that is not communicably connected to a management device, the management method being performed by using the management device, a terminal that is communicably connected to the management device, and the analyzer, the management method comprising: preparing, by the analyzer, management information that is to be obtained by the management device and that is included in information stored in the analyzer; obtaining the prepared management information by the terminal; and transmitting the obtained management information from the terminal to the management device.
G16H 40/60 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux
G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres
Disclosed is a maintenance method for an analyzer that is not communicably connected to a network outside of a facility, the maintenance method comprising: presenting, by a terminal that is communicably connected to the network outside of the facility, information about a process to be executed by the analyzer; reading, by the analyzer, the information having been presented by the terminal; and executing, by the analyzer, the process indicated by the information having been read.
Bacterial cells from a biological sample are exposed to a test antimicrobial agent in addition to multiple other antimicrobial agents or mixtures. A MIC value of the test antimicrobial agent is determined based on a phenotypic characteristic response of the bacterial cells to the test antimicrobial agent. The bacterial cells are classified based on respective phenotype characteristic responses of the bacterial cells to the other antimicrobial agent or mixtures and the classification is used to determine a CBP value for the test antimicrobial agent. The MIC and CBP values are then determined and can be used to determine whether the bacterial cells from the biological sample are susceptible or not to the test antimicrobial agent.
C12Q 1/18 - Test de l'activité antimicrobienne d'un matériau
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
A particle separation chip that separates particles contained in a specimen based on particle size may include a substrate comprising a micro flow path inside of the substrate; and a perforated sheet comprising holes. The micro flow path includes: a main flow path including an inlet arranged at upstream side, into which a specimen comprising a first particle, and a second particle that is smaller than the first particle is supplied; and a first outlet arranged at downstream side, from which a specimen comprising the first particle is discharged; and a branch flow path connected to the main flow path at branches along a flow direction of the main flow path, including a second outlet from which a specimen comprising the second particle is discharged at the downstream side. The main flow path and the branch flow path are connected via the holes of the perforated sheet at the branches.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
B01D 29/01 - Filtres à éléments filtrants stationnaires pendant la filtration, p. ex. filtres à aspiration ou à pression, non couverts par les groupes Leurs éléments filtrants avec des éléments filtrants plats
B01D 29/90 - Filtres à éléments filtrants stationnaires pendant la filtration, p. ex. filtres à aspiration ou à pression, non couverts par les groupes Leurs éléments filtrants comportant des dispositifs d'alimentation ou d'évacuation d'alimentation
95.
SPECIMEN MEASUREMENT SYSTEM AND SPECIMEN MEASUREMENT METHOD
Disclosed is a specimen measurement system including: a specimen measuring device that measures a specimen; a determination unit that determines whether or not the specimen is to be measured by a flow cytometer, based on a measurement result of the specimen measuring device.
Disclosed is a method for producing an anti-EGFR antibody, including: generating an anti-EGFR antibody having an amino acid sequence of the anti-EGFR antibody using a polynucleotide encoding the amino acid sequence; and collecting the anti-EGFR antibody, wherein the anti-EGFR antibody contains an HCDR1 including the amino acid sequence of SEQ ID NO: 1, an HCDR2 including the amino acid sequence SGG, an HCDR3 including the amino acid sequence of SEQ ID NO: 2, an LCDR1 including the amino acid sequence of SEQ ID NO: 3, an LCDR2 including the amino acid sequence YAS, and an LCDR3 including the amino acid sequence of SEQ ID NO: 4.
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
Disclosed is a specimen measurement apparatus that includes: a measurement unit configured to measure a specimen by using a reagent; a reagent container storage portion configured to store a reagent container in which the reagent is stored; a cooling unit configured to cool the reagent container storage portion; and a holder slidably mounted to the reagent container storage portion in a state where the holder holds the cooling unit.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
100.
SAMPLE MEASURING APPARTUS, INFORMATION READER, AND INFORMATION READING METHOD
A sample measuring apparatus according to one or more embodiments is disclosed. The apparatus may include the sample rack storage in which the sample rack holding the sample container is installed, the reagent rack storage in which the reagent rack holding the reagent container is installed, an information reader, and a first flection unit. The sample rack storage is geometrically placed at a position farther from the information reader than the reagent rack storage. The information reader reads the sample identification information of the sample container from the first reflected light acquired via the first flection unit, and reads the reagent identification information of the reagent container from the second reflected light acquired not via the first flection unit.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
