An isolator includes a first section, a second section, and a third section is disclosed. The first section is configured to secure the isolator in a mount that is defined through a mounting section. The second section is disposed over the first section and is configured to be supported by a first surface of the mounting section. The third section is disposed on top of the second section such that the second section is sandwiched between the first section and the third section. The second section dampens forces exerted on the third section or the first section from being transmitted therebetween. A method for manufacturing a pallet that is configured to be frozen is also disclosed. The method includes friction stir welding along a first joining edge and second joining edge that are abutted together to joined together to form a first segment.
An isolator includes a first section, a second section, and a third section is disclosed. The first section is configured to secure the isolator in a mount that is defined through a mounting section. The second section is disposed over the first section and is configured to be supported by a first surface of the mounting section. The third section is disposed on top of the second section such that the second section is sandwiched between the first section and the third section. The second section dampens forces exerted on the third section or the first section from being transmitted therebetween. A method for manufacturing a pallet that is configured to be frozen is also disclosed. The method includes friction stir welding along a first joining edge and second joining edge that are abutted together to joined together to form a first segment.
F16F 3/087 - Ensembles comprenant plusieurs ressorts en matière plastique ou similaire
F16F 15/08 - Suppression des vibrations dans les systèmes non rotatifs, p. ex. dans des systèmes alternatifsSuppression des vibrations dans les systèmes rotatifs par l'utilisation d'organes ne se déplaçant pas avec le système rotatif utilisant des moyens élastiques avec ressorts en caoutchouc
B65D 19/44 - Éléments ou dispositifs pour placer les objets sur les plates-formes
B65D 81/02 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu spécialement adaptés pour protéger leur contenu des dommages mécaniques
B65D 81/07 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu spécialement adaptés pour protéger leur contenu des dommages mécaniques maintenant le contenu en position éloignée des parois de l'emballage ou des autres pièces du contenu utilisant des moyens de suspension élastiques
B65D 77/04 - Objets ou matériaux enfermés dans plusieurs réceptacles disposés les uns dans les autres
3.
System for Simultaneous Distribution of Fluid to Multiple Vessels and Method of Using the Same
A fluid distribution system includes an input tube, a plurality of vessels, and a distribution hub. The input tube is configured to extend from a supply vessel. Each vessel of the plurality of vessels includes an inflow conduit. The distribution hub includes a single inlet and a plurality of outlets. The single inlet is defined in a bottom of the distribution hub and is in fluid communication with the input tube such that the distribution hub is configured to receive fluid from the input tube through the single inlet. Each outlet of the plurality of outlets is in fluid communication with the single inlet and in fluid communication with a respective inflow conduit such that the distribution hub is configured to provide an equal portion of the fluid received through the single inlet to each of the inflow conduits.
B67D 7/02 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail pour transférer des liquides autres que des carburants ou des lubrifiants
B67D 7/38 - Aménagements des tuyaux flexibles, p. ex. de la liaison de pilotage d'une moto-pompe
A storage container for aseptically storing and freezing a biopharmaceutical composition includes a frame, an expandable bladder, and a sensor system. The expandable bladder is supported within the frame having a filled state in which the expandable bladder is configured to hold the biopharmaceutical composition therein. The sensor system is secured to an exterior surface of the bladder. The sensor system is configured to transmit a signal indicative of a temperature of the exterior surface of the bladder which is correlated to a temperature of biopharmaceutical composition at a desired location within the expandable bladder in the filled state thereof.
A storage container for aseptically storing and freezing a biopharmaceutical composition includes a frame, an expandable bladder, and a sensor system. The expandable bladder is supported within the frame having a filled state in which the expandable bladder is configured to hold the biopharmaceutical composition therein. The sensor system is secured to an exterior surface of the bladder. The sensor system is configured to transmit a signal indicative of a temperature of the exterior surface of the bladder which is correlated to a temperature of biopharmaceutical composition at a desired location within the expandable bladder in the filled state thereof.
A01N 1/146 - Réceptacles non réfrigérés spécialement adaptés au transport ou au stockage de parties vivantes tout en les préservant
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
The invention relates to a continuous flow centrifuge with a rotor. The continuous flow centrifuge comprises a connecting section with connection conduits. Via the connection conduits an exchange of media in receptacles arranged in centrifugation chambers of the rotor is possible. A temperature control supply conduit and temperature control discharge conduit for a connecting section temperature control fluid both extend through the connecting section in order to counteract heating of the connecting section as a result of the flexing work and friction occurring therein. The connecting section temperature control fluid flows through the temperature control supply conduit and the temperature control discharge conduit in opposite flow directions. An electronic control unit (28) comprises control logic which controls (open loop or closed loop) the connecting section temperature control circuit.
A continuous flow centrifuge comprising a rotor comprising at least one centrifugation chamber and which is rotated about a rotor axis at a rotor speed, and a connecting section through which connecting conduits extend. A medium can be supplied to the centrifugation chamber via the connecting conduits during operation, and the medium can be discharged from the centrifugation chamber. One end section of the connecting section is fixed to the housing, while the other end section is rotated with the rotor. To avoid twisting of the connecting section, the connecting section is guided in a compensating rotor guiding device, which is rotated about the rotor axis at half the rotor speed. The compensating rotor guiding device may comprise a guiding contour whose radius of curvature in a first guiding contour section is larger than the radius of curvature in a second guiding contour section.
B04B 5/12 - Centrifugeurs dans lesquels l'action centrifuge agissant dans un récipient stationnaire est obtenue par des organes rotatifs autres que des tambours
B04B 5/04 - Appareils à chambre radiale pour séparer des mélanges essentiellement liquides, p. ex. butyromètres
B04B 11/02 - Alimentation ou déchargement en continuSystèmes de commande à cet effet
12 - Véhicules; appareils de locomotion par terre, par air ou par eau; parties de véhicules
Produits et services
Disposable containers specially designed for cryopreserving biopharmaceutical materials; protective rigid housing structures for receiving disposable containers for cryopreserving biopharmaceutical materials; frames for supporting disposable containers for cryopreserving biopharmaceutical materials, storage units for short or long storage of frames with supported disposable containers for cryopreserving biopharmaceutical materials. Transportation carts for disposable containers for cryopreserving biopharmaceutical materials.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
Microcarriers for use in manufacturing, laboratory use, and
research use; protein-coated microcarrier beads for use in
manufacturing, laboratory use, and research use; non-protein
coated microcarrier beads for use in manufacturing,
laboratory use, and research use; microcarriers for use in
preparing cell cultures and in cell culture applications;
kits consisting of microcarriers for use in manufacturing,
laboratory use, and research use; sterilized bags containing
microcarriers for use in manufacturing, laboratory use, and
research use.
A method for operating a clarification setup of a bioprocess installation, which clarification setup comprises a fluidized bed centrifuge and a pumping arrangement, wherein the fluidized bed centrifuge comprises at least one centrifuge chamber turned around a geometrical centrifuge axis, wherein the bioprocess installation comprises an electronic process control for controlling the fluidized bed centrifuge and pumping arrangement, wherein the fluidized bed centrifuge is being operated in a forward operation for a particle loading cycle and/or a particle washing cycle and in a backward operation for a particle discharging cycle, wherein in case where a particle loading cycle is provided, cell broth loaded into the centrifuge chamber proceeds to form a growing particle accumulation in the centrifuge chamber, wherein the clarification setup comprises a monitoring sensor arrangement with at least one optical sensor for producing monitoring sensor data, which are being transmitted to the electronic process control.
C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p. ex. fermenteurs commandés automatiquement
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
A method for operating a clarification setup, wherein the clarification setup comprises a fluidized bed centrifuge, wherein the fluidized bed centrifuge comprises at least two centrifuge chambers, wherein the fluidized bed centrifuge is being operated in a forward operation for a particle loading cycle and/or a particle washing cycle and in a backward operation for a particle discharging cycle wherein the clarification setup comprises a monitoring sensor arrangement with at least one sensor for producing monitoring sensor data, which are being transmitted to the electronic process control. In a monitoring routine, monitoring sensor data are being produced individually by the monitoring sensor arrangement and that during the loading cycle, in an adjusting routine, at least one parameter of the clarification setup is being adjusted based on the monitoring sensor data as to control the loading of the cell broth the centrifuge chambers individually according to a predefined adjusting strategy.
C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p. ex. fermenteurs commandés automatiquement
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
(1) Microcarriers for use in manufacturing, laboratory use, and research use; protein-coated microcarrier beads for use in manufacturing, laboratory use, and research use; non-protein coated microcarrier beads for use in manufacturing, laboratory use, and research use; microcarriers for use in preparing cell cultures and in cell culture applications; kits consisting of microcarriers for use in manufacturing, laboratory use, and research use; sterilized bags containing microcarriers for use in manufacturing, laboratory use, and research use.
13.
System for Simultaneous Distribution of Fluid to Multiple Vessels and Method of Using the Same
A fluid distribution system includes an input tube, a plurality of vessels, and a distribution hub. The input tube is configured to extend from a supply vessel. Each vessel of the plurality of vessels includes an inflow conduit. The distribution hub includes a single inlet and a plurality of outlets. The single inlet is defined in a bottom of the distribution hub and is in fluid communication with the input tube such that the distribution hub is configured to receive fluid from the input tube through the single inlet. Each outlet of the plurality of outlets is in fluid communication with the single inlet and in fluid communication with a respective inflow conduit such that the distribution hub is configured to provide an equal portion of the fluid received through the single inlet to each of the inflow conduits.
B67D 7/02 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail pour transférer des liquides autres que des carburants ou des lubrifiants
B67D 7/38 - Aménagements des tuyaux flexibles, p. ex. de la liaison de pilotage d'une moto-pompe
A composite article includes a lattice and an elastomeric section. The lattice includes a plurality of members that form an open-mesh frame defining a plurality of voids between the adjacent members of the frame. The elastomeric section is formed of an elastomer that is disposed about the lattice and within the voids of the lattice. The composite article may be a circular gasket, a gasket with a grip, a rectangular gasket, a vessel cap, a flask stand, and a handle for a hand tool.
B65D 41/00 - Capuchons, p. ex. couvercles à rebords ou capsules à sertissage, c.-à-d. éléments ayant des parties prenant sur la périphérie extérieure d'un col ou d'une paroi limitant une ouverture de versement ou de déchargeCouvercles de protection en forme de capuchons pour les éléments de fermeture, p. ex. couvercles décoratifs en feuille de métal ou en papier
B01L 9/00 - Dispositifs de supportDispositifs de serrage
B25G 1/10 - Fabrication des manches caractérisés par le matériau ou la forme
B29C 45/14 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet en incorporant des parties ou des couches préformées, p. ex. moulage par injection autour d'inserts ou sur des objets à recouvrir
B33Y 80/00 - Produits obtenus par fabrication additive
F16J 15/02 - Joints d'étanchéité entre surfaces immobiles entre elles
15.
TUBE HOLDING APPARATUSES FOR FILLING OF MULTIPLE CONTAINERS AND METHODS FOR USING THE SAME
A tube holding apparatus includes a body, a mount, a first guide, and a second guide. The body has a proximal end portion and a distal end portion. The mount is positioned between the proximal end portion and the distal end portion of the body. The mount is configured to secure the body to a valve tower. The first guide is secured about the proximal end portion of the body. The second guide is secured about the distal end portion of the body. The first guide and the second guide each configured to receive a portion of a transfer link that extends between a valve tower and a storage container such that a positive slope container to the valve tower.
B67C 3/26 - Têtes de remplissageDispositifs pour introduire les têtes de remplissage dans les goulots des bouteilles
B65B 37/02 - Approvisionnement ou alimentation des matériaux solides fluents, plastiques ou liquides, ou de masses en vrac, de petits objets, à emballer par pesanteur
16.
TUBE HOLDING APPARATUSES FOR FILLING OF MULTIPLE CONTAINERS AND METHODS FOR USING THE SAME
A tube holding apparatus includes a body, a mount a first guide, and a second guide. The body has a proximal end portion and a distal end portion. The mount is positioned between the proximal end portion and the distal end portion of the body. The mount is configured to secure the body to a valve tower. The first guide is secured about the proximal end portion of the body. The second guide is secured about the distal end portion of the body. The first guide and the second guide each configured to receive a portion of a transfer link that extends between a valve tower and a storage container such that a positive slope container to the valve tower.
B65B 3/00 - Emballage de matériaux plastiques, de semi-liquides, de liquides ou de liquides et solides mélangés, dans des réceptacles ou récipients individuels, p. ex. dans des sacs ou sachets, boîtes, cartons, bidons ou pots
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
17.
Tube holding apparatuses for filling of multiple containers and methods for using the same
A tube holding apparatus includes a body, a mount, a first guide, and a second guide. The body has a proximal end portion and a distal end portion. The mount is positioned between the proximal end portion and the distal end portion of the body. The mount is configured to secure the body to a valve tower. The first guide is secured about the proximal end portion of the body. The second guide is secured about the distal end portion of the body. The first guide and the second guide each configured to receive a portion of a transfer link that extends between a valve tower and a storage container such that a positive slope container to the valve tower.
B67C 3/26 - Têtes de remplissageDispositifs pour introduire les têtes de remplissage dans les goulots des bouteilles
B65B 37/02 - Approvisionnement ou alimentation des matériaux solides fluents, plastiques ou liquides, ou de masses en vrac, de petits objets, à emballer par pesanteur
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
Microcarriers for use in manufacturing, laboratory use, and research use; protein-coated microcarrier beads for use in manufacturing, laboratory use, and research use; non-protein coated microcarrier beads for use in manufacturing, laboratory use, and research use; microcarriers for use in preparing cell cultures and in cell culture applications; kits consisting of microcarriers for use in manufacturing, laboratory use, and research use; microcarriers contained in sterilized bags for use in manufacturing, laboratory use, and research use
19.
Valve switching system for selectively interconnecting components of a bioprocess installation
Various embodiments are directed to a valve switching system for selectively interconnecting components of a bioprocess installation, comprising a valve switching cassette and an actuator block. It is proposed, that the valve switching cassette comprises a perforated backer plate securing a valve membrane structure to a cassette manifold, that the actuator block comprises a drive membrane structure with at least one drive membrane and a perforated backer plate securing the drive membrane structure to an actuator block body, wherein for selectively switching valve units, an actuator of the actuator block may urge the drive membrane structure through aligned perforation holes of both backer plates into engagement with the valve membrane structure.
G01N 30/46 - Modèles d'écoulement utilisant plus d'une colonne
B01D 15/18 - Adsorption sélective, p. ex. chromatographie caractérisée par des caractéristiques de structure ou de fonctionnement relatives aux différents types d'écoulement
20.
VALVE SWITCHING SYSTEM FOR SELECTIVELY INTERCONNECTING COMPONENTS OF A BIOPROCESS INSTALLATION
x,yx,yx,y), an actuator of the actuator block (16) may urge the drive membrane structure (23) through aligned perforation holes (25, 26) of both backer plates (22, 24) into engagement with the valve membrane structure (20).
B01D 15/18 - Adsorption sélective, p. ex. chromatographie caractérisée par des caractéristiques de structure ou de fonctionnement relatives aux différents types d'écoulement
F16K 7/00 - Dispositifs d'obturation à diaphragme, p. ex. dont un élément est déformé, sans être déplacé entièrement, pour fermer l'ouverture
G01N 30/46 - Modèles d'écoulement utilisant plus d'une colonne
G01N 30/32 - Contrôle des paramètres physiques du fluide vecteur de la pression ou de la vitesse
21.
QUICK DISSOLVING CAVITY FORMING STRUCTURE FOR INJECTION MOLDED STRUCTURES
A method of molding an article includes positioning a dissolvable insert within a mold, filling the mold with material to form an article within the mold and about the dissolvable insert, and at least partially dissolving the dissolvable insert from within the article. The dissolvable insert forms internal features of the article and includes a porous core.
B29C 45/44 - Démoulage ou éjection des objets formés d'objets à contre-dépouille
B29C 33/52 - Moules ou noyauxLeurs détails ou accessoires comportant des moyens ou conçus spécialement pour faciliter le démoulage d'objets, p. ex. des objets à contre-dépouille solubles ou fusibles
The invention relates to a continuous flow centrifuge (1) comprising a rotor (6). The continuous flow centrifuge (1) comprises a connecting strand (12) having connection lines (16, 17), via which an exchange of media in containers (8a, 8b) arranged in the centrifugation chambers of the rotor (6) is possible. According to the invention, a temperature-control supply line (14) and a temperature-control discharge line (16) for a connecting strand temperature-control fluid extends through the connecting strand (12) in order to counteract a heating of the connecting strand (12) due to flexing and friction occurring therein. The connecting strand temperature-control fluid flows through the temperature-control supply line (14) and the temperature-control discharge line (15) in opposing flow directions. An electronic control unit (28) has a control logic which controls the connecting strand temperature-control power of a connecting strand temperature-control circuit (36) in an open-loop or closed-loop manner.
The invention relates to a continuous-flow centrifuge comprising a rotor which has at least one centrifugation chamber and rotates about a rotor axis (7) at a rotor speed. The continuous-flow centrifuge comprises a connecting strand (12) through which connecting lines (16, 17) extend. A medium can be supplied to the centrifugation chamber, and the medium can be discharged from the centrifugation chamber, via the connecting lines (16, 17) during operation of the continuous-flow centrifuge with the rotor rotating. One end region (18) of the connecting strand (12) is fixed to the housing, whereas the other end region (19) of the connecting strand (12) rotates with the rotor. To prevent the connecting strand (12) from twisting, the connecting strand (12) is guided in a compensation-rotor guide device (20) (in particular a guide tube (21)) which rotates about the rotor axis (7) at half the rotor speed. According to the invention, the compensation-rotor guide device (20) has a guide contour (27), the radius of curvature (32) of which is greater in a first guide-contour section (28) than the radius of curvature (33) in a second guide-contour section (29). As a result, the service life of the connecting strand (12) can be increased.
A tilting mechanism including a base, a tilting deck, four hinges, and a lifting member. Each hinge is positioned adjacent a corner of the base and the tilting deck. Each hinge includes a globe and a receiver with the globe or the receiver secured to the base frame or the deck frame and the other secured to the other of the base or the tilting deck. Each hinge includes a locking member that selectively secures a globe within a respective receiver. The lifting member is secured at a center of the base frame and a center of the deck frame. The lifting member is configured to urge the tilting deck away from the base such that selective engagement allows for tilting of the tilting deck relative to the base in at least four directions.
B62B 3/08 - Voitures à bras ayant plus d'un essieu portant les roues servant au déplacementDispositifs de direction à cet effetAppareillage à cet effet comportant des réceptacles de chargement à bascule
B62B 3/02 - Voitures à bras ayant plus d'un essieu portant les roues servant au déplacementDispositifs de direction à cet effetAppareillage à cet effet comportant des parties réglables, rabattables, attachables, détachables ou transformables
B67D 7/84 - Carters, armoires ou châssisChariots ou supports mobiles du même genre
A tilting mechanism including a base, a tilting deck, four hinges, and a lifting member. Each hinge is positioned adjacent a corner of the base and the tilting deck. Each hinge includes a globe and a receiver with the globe or the receiver secured to the base frame or the deck frame and the other secured to the other of the base or the tilting deck. Each hinge includes a locking member that selectively secures a globe within a respective receiver. The lifting member is secured at a center of the base frame and a center of the deck frame. The lifting member is configured to urge the tilting deck away from the base such that selective engagement allows for tilting of the tilting deck relative to the base in at least four directions.
B60P 1/16 - Véhicules destinés principalement au transport des charges et modifiés pour faciliter le chargement, la fixation de la charge ou son déchargement avec un mouvement de basculement de l'élément supportant ou contenant la charge actionné par un fluide
E05D 15/50 - Suspensions pour battants permettant des manœuvres alternées pour ouverture à l'un ou l'autre des deux bords opposés
A61M 1/02 - Appareils pour transfusion sanguine d'un corps à un autre
B62B 3/08 - Voitures à bras ayant plus d'un essieu portant les roues servant au déplacementDispositifs de direction à cet effetAppareillage à cet effet comportant des réceptacles de chargement à bascule
26.
SMALL VOLUME SYSTEM AND METHODS OF EVALUATING THE STABILITY OF BIOPHARMACEUTICAL COMPOSITIONS
An analysis container includes an outer tube and a plurality of inner tubes. The outer tube defines a buffer volume that is configured to receive a buffer material. The plurality of inner tubes is disposed within the buffer volume. Each inner tube has an inner diameter equal to or less than 6 mm and is configured to receive a biopharmaceutical composition therein. The outer tube is configured such that the buffer material and the biopharmaceutical composition are axially frozen.
G01N 25/04 - Recherche ou analyse des matériaux par l'utilisation de moyens thermiques en recherchant les changements d'état ou de phaseRecherche ou analyse des matériaux par l'utilisation de moyens thermiques en recherchant le frittage du point de fusionRecherche ou analyse des matériaux par l'utilisation de moyens thermiques en recherchant les changements d'état ou de phaseRecherche ou analyse des matériaux par l'utilisation de moyens thermiques en recherchant le frittage du point de congélationRecherche ou analyse des matériaux par l'utilisation de moyens thermiques en recherchant les changements d'état ou de phaseRecherche ou analyse des matériaux par l'utilisation de moyens thermiques en recherchant le frittage du point de ramollissement
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
27.
SMALL VOLUME SYSTEM AND METHODS OF EVALUATING THE STABILITY OF BIOPHARMACEUTICAL COMPOSITIONS
An analysis container includes an outer tube and a plurality of inner tubes. The outer tube defines a buffer volume that is configured to receive a buffer material. The plurality of inner tubes is disposed within the buffer volume. Each inner tube has an inner diameter equal to or less than 6 mm and is configured to receive a biopharmaceutical composition therein. The outer tube is configured such that the buffer material and the biopharmaceutical composition are axially frozen.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
An organizer assembly including a belt and a ribbon. The ribbon has a first clamp member, a second clamp member, and a first carrier portion. The first clamp member is configured to receive a conduit or a support to fix the conduit or the support relative to the ribbon. The belt includes an elongated body that is slidably received in the first carrier portion. The organizer assembly may include one or more adapters that are received in a respective clamp member of the ribbon and configured to receive a conduit or a support to fix the conduit or support relative to the ribbon.
F16L 3/22 - Supports pour tuyaux, pour câbles ou pour conduits de protection, p. ex. potences, pattes de fixation, attaches, brides, colliers spécialement adaptés pour supporter un certain nombre de tuyaux parallèles séparés par un espace
F16L 3/02 - Supports pour tuyaux, pour câbles ou pour conduits de protection, p. ex. potences, pattes de fixation, attaches, brides, colliers entourant partiellement le tuyau, le câble ou le conduit de protection
A clamp for closing a flexible tube includes an anvil and a hammer. The anvil includes a passage and a slot defined therein. The passage is configured to receive a flexible tube therethrough. The hammer is slidably received within the slot of the anvil. The hammer is securable in a first position in which the passage of the anvil is substantially unoccluded and a second position in which the passage of the anvil is occluded. The hammer and the anvil are configured to prevent fluid from flowing through the flexible tube received in the passage when the hammer is in the closed position. The hammer is substantially within the anvil in the closed position.
F16K 7/06 - Dispositifs d'obturation à diaphragme, p. ex. dont un élément est déformé, sans être déplacé entièrement, pour fermer l'ouverture à diaphragme tubulaire dont l'étranglement est assuré par une force extérieure radiale par tige filetée, came ou autre moyen mécanique
A61M 39/28 - Moyens de serrage pour l'écrasement des tubes flexibles, p. ex. brides de serrage à rouleaux
30.
SEMI-RIGID BIOCONTAINER AND METHODS OF MANUFACTURING THE SAME
A biocontainer including a rigid frame and a flexible membrane. The frame includes a lattice core. The membrane may flex to adjust to a volume of biomaterial sealed within the interior of the biocontainer as a temperature of the biomaterial changes.
A biocontainer including a rigid frame and a flexible membrane. The frame includes a lattice core. The membrane may flex to adjust to a volume of biomaterial sealed within the interior of the biocontainer as a temperature of the biomaterial changes.
The invention is directed to a valve switching system for selectively interconnecting components of a bioprocess installation (2), comprising a valve switching cassette (15) and an actuator block (16). It is proposed, that the valve switching cassette (15) comprises a perforated sandwich plate (22) with perforation holes (23), which sandwich plate (22) is placed between the cassette manifold (17) and the actuator block body (21).
B01D 15/18 - Adsorption sélective, p. ex. chromatographie caractérisée par des caractéristiques de structure ou de fonctionnement relatives aux différents types d'écoulement
G01N 30/46 - Modèles d'écoulement utilisant plus d'une colonne
A valve switching cassette for selectively interconnecting components of a bioprocess installation, wherein the valve switching cassette comprises at least one fluid flow system of ports and fluid lines, which fluid flow system includes primary ports, communicating with primary fluid lines, and secondary ports, communicating with secondary fluid lines, wherein the valve switching cassette comprises an array of switchable valve units for selectively interconnecting the primary fluid lines with the secondary fluid lines via transfer fluid lines. It is prosed, that the valve switching cassette comprises a transfer plate with apertures and an elastically deformable membrane structure on each flat side of the transfer plate, that at least part of the primary fluid lines and secondary fluid lines are extending between the transfer plate and one of the membrane structures and that the transfer fluid lines are at least partly provided by the apertures.
G01N 30/46 - Modèles d'écoulement utilisant plus d'une colonne
B01D 15/18 - Adsorption sélective, p. ex. chromatographie caractérisée par des caractéristiques de structure ou de fonctionnement relatives aux différents types d'écoulement
G01N 30/20 - Injection utilisant une valve d'échantillonnage
B01D 15/14 - Adsorption sélective, p. ex. chromatographie caractérisée par des caractéristiques de structure ou de fonctionnement relatives à l'introduction de l'alimentation dans l'appareil
34.
VALVE SWITCHING CASSETTE FOR SELECTIVELY INTERCONNECTING COMPONENTS OF A BIOPROCESS INSTALLATION
ppssx,ypspss) are extending between the transfer plate (17) and one of the membrane structures (19, 20) and that the transfer fluid lines (T) are at least partly provided by the apertures (18).
Metal collars for aseptic disconnection of laboratory tubing; aluminum collars for aseptic disconnection of laboratory tubing; sealing caps of metal for aseptic disconnection of laboratory tubing; sealing caps of metal for aseptic disconnection of laboratory tubing for use in the food and beverage, pharmaceutical, and biopharmaceutical industries Power tools, namely, laboratory cutting tools for tubing separation and creation of aseptic seals; power-operated cutting tools for metal collars and laboratory tubing; power-operated tools, namely, cutting tools for tubing separation; battery-operated cutting tools for metal collars and laboratory tubing; battery-operated tools, namely, cutting tools for tubing separation Hand tools, namely, laboratory cutting tools for tubing separation and creation of aseptic seals; hand-operated cutting tools for metal collars and laboratory tubing; hand-operated tools, namely, cutting tools for tubing separation Non-metallic sealing caps for laboratory tubing; non-metallic protective caps for use in the food and beverage, pharmaceutical, and biopharmaceutical industries, namely, for use on laboratory tubing and metal collars; silicone protective caps in the nature of sealing caps for metal collars and laboratory tubing
The invention is directed to a method for operating a clarification setup (1) of a bioprocess installation (2), wherein the clarification setup (1) comprises a fluidized bed centrifuge (3) for the clarification of a cell broth by centrifugation, wherein the fluidized bed centrifuge (3) comprises at least two centrifuge chambers (9-12), wherein the fluidized bed centrifuge (3) is being operated in a forward operation for a particle loading cycle and/or a particle washing cycle and in a backward operation for a particle discharging cycle, wherein during the particle loading cycle, cell broth loaded into the centrifuge chamber (9-12) proceeds to form a growing particle accumulation in the centrifuge chamber (9-12), wherein the clarification setup (1) comprises a monitoring sensor arrangement (17) with at least one, preferably optical, sensor (18) for producing monitoring sensor data, which are being transmitted to the electronic process control (14). It is proposed that in a monitoring routine, for at least part of the centrifuge chambers (9-12), monitoring sensor data (19) are being produced individually by the monitoring sensor arrangement (17) and that during the loading cycle, in an adjusting routine, at least one parameter of the clarification setup (1) is being adjusted based on the monitoring sensor data (19) as to control the loading of the cell broth the centrifuge chambers (9-12) individually according to a predefined adjusting strategy.
C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p. ex. fermenteurs commandés automatiquement
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
The invention is directed to a method for operating a clarification setup (1) of a bioprocess installation (2), which clarification setup comprises a fluidized bed centrifuge (3) and a pumping arrangement (4), wherein the fluidized bed centrifuge (3) comprises at least one centrifuge chamber (5) turned around a geometrical centrifuge axis (6), wherein the bioprocess installation (2) comprises an electronic process control (7) for controlling the fluidized bed centrifuge (3) and pumping arrangement (4), wherein the fluidized bed centrifuge (3) is being operated in a forward operation for a particle loading cycle (8) and/or a particle washing cycle (9) and in a backward operation for a particle discharging cycle (10), wherein in case where a particle loading cycle (8) is provided, cell broth loaded into the centrifuge chamber (5) proceeds to form a growing particle accumulation in the centrifuge chamber (5), wherein the clarification setup (1) comprises a monitoring sensor arrangement (11) with at least one optical sensor (12) for producing monitoring sensor data, which are being transmitted to the electronic process control (7). It is proposed that in a monitoring routine (13), image-related data (14) representing an optical image (15) of the centrifuge chamber content (16) are being produced by the monitoring sensor arrangement (11) and a particle filling level (17) is being calculated by the electronic process control (7) from the image-related data (14) based on a calculation model (18).
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p. ex. fermenteurs commandés automatiquement
38.
System for simultaneous distribution of fluid to multiple vessels and method of using the same
A fluid distribution system includes an input tube, a plurality of vessels, and a distribution hub. The input tube is configured to extend from a supply vessel. Each vessel of the plurality of vessels includes an inflow conduit. The distribution hub includes a single inlet and a plurality of outlets. The single inlet is defined in a bottom of the distribution hub and is in fluid communication with the input tube such that the distribution hub is configured to receive fluid from the input tube through the single inlet. Each outlet of the plurality of outlets is in fluid communication with the single inlet and in fluid communication with a respective inflow conduit such that the distribution hub is configured to provide an equal portion of the fluid received through the single inlet to each of the inflow conduits.
B67D 7/02 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail pour transférer des liquides autres que des carburants ou des lubrifiants
B67D 7/38 - Aménagements des tuyaux flexibles, p. ex. de la liaison de pilotage d'une moto-pompe
An organizer assembly including a belt and a ribbon. The ribbon has a first clamp member, a second clamp member, and a first carrier portion. The first clamp member is configured to receive a conduit or a support to fix the conduit or the support relative to the ribbon. The belt includes an elongated body that is slidably received in the first carrier portion. The organizer assembly may include one or more adapters that are received in a respective clamp member of the ribbon and configured to receive a conduit or a support to fix the conduit or support relative to the ribbon.
An organizer assembly including a belt and a ribbon. The ribbon has a first clamp member, a second clamp member, and a first carrier portion. The first clamp member is configured to receive a conduit or a support to fix the conduit or the support relative to the ribbon. The belt includes an elongated body that is slidably received in the first carrier portion. The organizer assembly may include one or more adapters that are received in a respective clamp member of the ribbon and configured to receive a conduit or a support to fix the conduit or support relative to the ribbon.
F16L 3/22 - Supports pour tuyaux, pour câbles ou pour conduits de protection, p. ex. potences, pattes de fixation, attaches, brides, colliers spécialement adaptés pour supporter un certain nombre de tuyaux parallèles séparés par un espace
F16L 3/02 - Supports pour tuyaux, pour câbles ou pour conduits de protection, p. ex. potences, pattes de fixation, attaches, brides, colliers entourant partiellement le tuyau, le câble ou le conduit de protection
41.
Thermal capacitors, systems, and methods for rapid freezing or heating of biological materials
A thermal capacitor includes a shell and a PCM. The shell includes a first major surface that is configured to contact a container including media to be frozen. The shell defines a cavity in which the PCM is disposed. The PCM has a transition temperature in a range of −80 degrees Celsius to −50 degrees Celsius and is configured to rapidly freeze media from room temperature to −60 degrees Celsius with the container including the media in contact with the shell in an enclosed space.
A thermal capacitor (100) includes a shell (110) and a PCM (150). The shell includes a first major surface (113, 117) that is configured to contact a container including media to be frozen. The shell defines a cavity (140) in which the PCM is disposed. The PCM has a transition temperature in a range of -80 degrees Celsius to -50 degrees Celsius and is configured to rapidly freeze media from room temperature to -60 degrees Celsius. Also disclosed are a rapid freezing system comprising a ULT Freezer and such a thermal capacitor, and a rapid freezing system comprising a rack and a plurality of such thermal capacitors. Further disclosed is a method of rapidly freezing media, comprising charging a plurality of such thermal capacitors disposed within a ULT Freezer, and placing a plurality of media containers in contact with at least one of the plurality of thermal capacitors.
F25D 3/00 - Dispositifs utilisant d'autres agents froidsDispositifs utilisant des récipients conservant le froid
F28D 20/02 - Appareils ou ensembles fonctionnels d'accumulation de chaleur en généralAppareils échangeurs de chaleur de régénération non couverts par les groupes ou utilisant la chaleur latente
43.
Thermal Capacitors, Systems, and Methods for Rapid Freezing or Heating of Biological Materials
A carrier for receiving a vessel includes a body that defines a well. The well is sized and dimensioned to receive a vessel including media. The body is configured to urge the vessel received in the well towards an external wall of the body to enhance thermal energy transfer into or out of the media within the vessel. A box assembly for supporting media during thermal changes includes a box, a vessel, and a carrier is also disclosed.
A carrier for receiving a vessel includes a body that defines a well sized and dimensioned to receive the vessel. A box assembly for supporting media during thermal changes is also disclosed, which includes a box (310) having a fixed wall assembly (320), a vessel (20), and a carrier (304), and wherein the carrier urges the vessel towards a thermal transfer wall (322) of the fixed wall assembly. The carrier may include a thermal energy transfer element to enhance thermal energy transfer into and out of the vessel. Also disclosed are a fluid distribution system comprising a fluid distribution hub; a frame supporting the fluid distribution hub and including an upper support; a plurality of carriers supported about the fluid distribution hub on the upper support; and a plurality of vessels. Further disclosed is a method of rapidly freezing media.
A fluid connector includes a body that has a first end and a second end. The first end defines a first opening that has a first diameter and the second end defines a second opening that has a second diameter different from the first diameter. The body has an inner surface defining a channel that extends from the first opening to the second opening. The inner surface smoothly extending from the first end to the second end. The first connector configured to prevent foaming of media flowed therethrough as a flow diameter of the media transition from the first diameter to the second diameter.
Method for the forming of a fluid-tight separating closure of a conduit (1) involving the following steps:
providing of a conduit (1) with a sleeve (2),
positioning of the conduit (1) with the sleeve (2) between a die (3) and a stamp (4),
compressing of the sleeve (2) by a relative movement between the die (3) and the stamp (4) in order to form a closure (5);
severing of the closure (5) in a compressed region (6) by a severing tool (7) such that a contact line (8) between the severing tool (7) and the sleeve (2) during severing is shorter than an obtained severing edge (9) of the sleeve (2).
B23D 15/04 - Machines à cisailler ou dispositifs de cisaillage taillant au moyen de lames se déplaçant parallèlement les unes par rapport aux autres n'ayant qu'une lame mobile
A fluid connector includes a body that has a first end and a second end. The first end defines a first opening that has a first diameter and the second end defines a second opening that has a second diameter different from the first diameter. The body has an inner surface defining a channel that extends from the first opening to the second opening. The inner surface smoothly extending from the first end to the second end. The first connector configured to prevent foaming of media flowed therethrough as a flow diameter of the media transition from the first diameter to the second diameter.
F16L 33/213 - Segments, manchons ou autres organes d'une seule pièce enserrant la manche ou dilatés à l'intérieur de la manche au moyen d'outilsAgencements utilisant de tels organes avec uniquement un manchon dilaté à l'intérieur de la manche
B67D 7/38 - Aménagements des tuyaux flexibles, p. ex. de la liaison de pilotage d'une moto-pompe
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
11 - Appareils de contrôle de l'environnement
12 - Véhicules; appareils de locomotion par terre, par air ou par eau; parties de véhicules
17 - Produits en caoutchouc ou en matières plastiques; matières à calfeutrer et à isoler
20 - Meubles et produits décoratifs
Produits et services
(1) Containers, and transportation and packaging articles, of metal for storage and transport of biological, biopharmaceutical, medical and pharmaceutical products; metal containers for holding and transporting flexible pouches for biological, medical or pharmaceutical liquids; Containers of metal for storage and transport of biological, biopharmaceutical, medical and pharmaceutical products; Metal pallets; Metal racks for storage of containers filled with biopharmaceutical materials; Metallic frames for supporting disposable containers for biopharmaceutical materials
(2) Mixing machines for use in biochemistry, biopharmaceutical production, clinical chemistry and microbiology; Mixing machines for mixing and homogenizing liquids in the pharmaceutical and chemical industries; Lifting apparatus for transfer and loading/unloading of pharmaceutical and biopharmaceutical ingredients; Packaging machines, namely, liquid container fillers; Filling machines for biological, biopharmaceutical, medical and pharmaceutical products; Machines for filling containers in the nature of disposable plastic bags with biopharmaceutical liquids; Dispensing machines for biological, biopharmaceutical, medical and pharmaceutical products; Dispensing machines for emptying containers filled with biopharmaceutical liquids; Control devices for machines for use in biochemistry, biopharmaceutical production, clinical chemistry and microbiology
(3) Laboratory measuring apparatus, namely, mass comparators, load cells for use in industrial and laboratory weighing systems, mechanical, electric and electronic parts and fittings for scales and weighing installations namely, electronic scales for industrial use, electronic load modules, electric metal detectors, electronic air filter testing machines, electronic liquid filters testing machines, microscopes, spectrophotometers, fluorescence spectrometer, NIR spectrometers, and turbidity meters and parts and fittings therefor, refractometers, PH meters, moisture meters, microwave resonance spectrometer, measuring sensor for analysing enzymatic reactions, electrodes for laboratory use, conductivity meters, spectrometers for determining biomass, pressure and temperature, ultrasonic flow meters, automatic chromatography apparatus for laboratory use, chromatography columns for laboratory use, microplate readers, microplate stackers, microplate washers, surface plasmon resonance (SPR) spectrometer, spectrometer using bio-layer interferometry for determination of the affinity, kinetics, and concentration of molecules, antibodies or proteins, filters for collecting and filtering airborne germs, for use in biochemistry, biopharmaceutical production, clinical chemistry and microbiology; laboratory controllers and regulators, namely, pH controllers for fermenters and bioreactors, pump controllers for liquid handling systems, pressure controllers for managing gas in laboratory reactors and chromatographic systems, gas flow controllers microfluidic devices, analytical instruments, and automated dispensing systems, pipette controllers, humidity regulators for use in biochemistry, biopharmaceutical production, clinical chemistry and microbiology; Laboratory sensors and detectors, namely sensors for measuring distance, chemical concentrations in aqueous solutions and gases, turbidity, radiation, and temperature, biosensors for analyzing chemical and biological samples for measuring the presence or absence, concentration, association, affinity, binding rates, specificity and functional properties of biomolecules, namely, chemical compounds, sugars, peptides, proteins, oligonucleotides, DNA, RNA, aptamers, cells, virus, bacteria, antibodies and antibody fragments for use in biochemistry, clinical chemistry and microbiology; Laboratory electrical controllers, namely, electrical pH controllers for fermenters and bioreactors, electrical pump controllers for liquid handling systems, electrical pressure controllers for managing gas in laboratory reactors and chromatographic systems, electrical gas flow controllers microfluidic devices, analytical instruments, and automated dispensing systems for use in biochemistry, biopharmaceutical production, clinical chemistry and microbiology; Temperature controllers for chilling biopharmaceutical materials in disposable containers designed for cryopreservation; Temperature controllers for controlling the temperature of biopharmaceutical materials held in disposable containers designed for cryopreservation; Disposable storage containers for cryopreservation of biopharmaceutical materials; Protective frames for use with disposable containers for biopharmaceutical materials; Apparatus for mixing biopharmaceutical media, in particular by vibration, rotation and wave motion, namely, laboratory shakers, platforms for laboratory vibrating shakers, in particular with measuring stations for collecting physical data and with interfaces for exchanging data with external apparatus, laboratory centrifuges, vessel holders for laboratory centrifuges, laboratory centrifuge beakers, laboratory centrifuge chambers, orbital laboratory shakers, rocking motion laboratory shaker, vibration laboratory shaker; Weighing apparatus and instruments and parts therefor, namely, laboratory scales and balances, electronic scales not for medical use, electronic load modules; weighing apparatus and instruments and parts therefor, namely, laboratory scales and balances, electronic scales not for medical use, electronic load modules for weighing the amount of liquids filled into and dispensed from disposable containers; Automated liquid dispensing machines; Dosage dispensers, Liquid dosage devices that measure the amounts to be dispensed
(4) Disposable storage containers specially designed for cryopreserving biopharmaceutical materials; protective rigid housing structures made of plastic and stainless steel for receiving disposable containers for cryopreserving biopharmaceutical materials; frames for protecting disposable containers for cryopreserving biopharmaceutical materials; storage containers and transportation carts for disposable containers for cryopreserving biopharmaceutical materials; sleeves and frames for use with disposable containers for the low temperature control of biopharmaceutical materials for medical purposes; weighing apparatus and instruments and parts therefor, namely, electronic scales for medical use; weighing apparatus and instruments and parts therefor, namely, electronic scales for medical use for weighing the amount of liquids filled into and dispensed from disposable containers
(5) Refrigerating and freezing containers for biopharmaceutical materials; Refrigerators, chillers for industrial process cooling and freezers for medical storage purposes; Refrigerating containers; Refrigerated shipping containers; Temperature controlled shipping containers; Refrigerated medical container for storage, transportation and cooling of medicines and pharmaceuticals; Chillers for freezing biopharmaceutical materials; Laboratory freezers for cryogenic preservation; Heaters for thawing frozen biopharmaceutical materials; Chillers and heaters for processing biopharmaceutical materials; Storage containers equipped with temperature controllers for biopharmaceutical materials
(6) Mobile storage carts for transporting disposable containers for cryopreserving biopharmaceutical materials; Electric lift trucks; Forklift trucks
(7) Thermally insulated containers for the transport and storage of temperature sensitive biopharmaceutical materials; Thermal insulation sleeves for storage and transportation of biopharmaceutical materials
(8) Non-metallic containers for storage, and closures and holders therefor; Containers, not of metal, for storage or transport; Non-metallic containers for biopharmaceutical liquids; Packaging containers of plastic; Plastic insulated shipping containers for transporting frozen biological, biopharmaceutical, medical and pharmaceutical materials; Plastic shipping and storage boxes; crates and pallets, of wood and plastic; Disposable storage containers made of plastic for storage and transport of frozen biopharmaceutical materials; protective rigid housing made of plastic for receiving disposable storage containers for biopharmaceutical materials, Plastic frames for supporting disposable storage containers for biopharmaceutical materials; Plastic sample bag cover specifically adapted for disposable storage containers for biopharmaceutical materials
03 - Produits cosmétiques et préparations de toilette; préparations pour blanchir, nettoyer, polir et abraser.
07 - Machines et machines-outils
09 - Appareils et instruments scientifiques et électriques
Produits et services
(1) Packaging machines, namely, liquid container fillers; Filling machines; Machines for filling containers with biopharmaceutical liquids; Dispensing machines; Dispensing machines for emptying containers filled with biopharmaceutical liquids; Machines for filling and emptying disposable plastic bags with biopharmaceutical liquids; Fluid pumps; Pump control valves; Control devices for machines
(2) Measuring apparatus and instruments; controllers and regulators; Sensors and detectors; Automatic control apparatus; Programmable control apparatus; Automatic control apparatus for controlling filling and dispensing machines; Automatic liquid-flow control machines and instruments; Automatic liquid-flow control machines and instruments Measuring and control devices for processing biopharmaceutical liquids; Automatic control valves; Control valves for regulating the flow of biopharmaceutical liquids; Automatic control valves for controlling the flow of biopharmaceutical liquids into and out of disposable containers; Weighing apparatus and instruments and parts therefor; weighing apparatus for weighing the amount of biopharmaceutical liquids filled into and dispensed from disposable containers; Automated liquid dispensing machines; Dosage dispensers, Liquid dosage devices that measure the amounts to be dispensed; Software for monitoring, analysing, controlling and running physical world operations; Machine control software; Process controlling software; Software for controlling and operating machines for packaging and dispensing biopharmaceutical liquids
50.
QUICK DISSOLVING CAVITY FORMING STRUCTURE FOR INJECTION MOLDED STRUCTURES
A method of molding an article includes positioning a dissolvable insert within a mold, filling the mold with material to form an article within the mold and about the dissolvable insert, and at least partially dissolving the dissolvable insert from within the article. The dissolvable insert forms internal features of the article and includes a porous core.
B21K 5/04 - Fabrication d'outils ou de parties d'outils, p. ex. de pinces d'outils de perçage ou autres outils pour faire ou pour usiner des trous d'outils hélicoïdaux, p. ex. forets, alésoirs
B28B 1/14 - Fabrication d'objets façonnés à partir du matériau par simple coulée, le matériau n'étant ni alimenté sous pression, ni réellement compacté
B28B 7/34 - Moules, noyaux ou mandrins en matériau particulier, p. ex. en matériau destructible
B29C 67/00 - Techniques de façonnage non couvertes par les groupes , ou
C04B 35/44 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base d'aluminates
A clamp for closing a flexible tube includes an anvil and a hammer. The anvil includes a passage and a slot defined therein. The passage is configured to receive a flexible tube therethrough. The hammer is slidably received within the slot of the anvil. The hammer is securable in a first position in which the passage of the anvil is substantially unoccluded and a second position in which the passage of the anvil is occluded. The hammer and the anvil are configured to prevent fluid from flowing through the flexible tube received in the passage when the hammer is in the closed position. The hammer is substantially within the anvil in the closed position.
Disclosed is a system for freezing, storing, transporting, and thawing biopharmaceutical product, comprising a stationary equipment and one or more movable pallets, each pallet configured to carry one or more container units, each containing biopharmaceutical product, the stationary equipment comprising a gas circulating unit configured to cause a circulation of cold gas and/or warm gas, from a pull inlet toward a blow outlet, wherein there is provided at least a first side plenum having one or more gas conveying channel therein, configured to be fluidly coupled to the blow outlet of the gas circulating unit, the first side plenum having a plurality of outlet ports directed toward an interior volume of the pallet, wherein the gas circulates substantially in a horizontal direction in the interior volume of the pallet, and wherein a shaking arrangement is provided.
B01F 31/20 - Mélange du contenu de récipients indépendants, p. ex. de tubes à essai
B65D 19/00 - Palettes ou plates-formes analogues, avec ou sans parois latérales, pour supporter les charges à soulever ou à déposer
F25D 17/06 - Dispositions pour la circulation des fluides de refroidissementDispositions pour la circulation de gaz, p. ex. d'air, dans les enceintes refroidies pour la circulation de gaz, p. ex. convection naturelle par circulation d'air forcée
F25D 25/00 - Introduction, port ou déchargement des produits à refroidir
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
12 - Véhicules; appareils de locomotion par terre, par air ou par eau; parties de véhicules
20 - Meubles et produits décoratifs
Produits et services
Metal pallets; Metal racks for storage of containers filled with biopharmaceutical materials; Metallic frames for supporting disposable containers for biopharmaceutical materials. Lifting apparatus. Frames for use with disposable containers for biopharmaceutical materials, the aforementioned goods for pharmaceutical purposes; Weighing apparatus and instruments and parts therefor; Weighing apparatus for weighing the amount of liquids filled into and dispensed from disposable containers. Protective rigid housing structures for receiving disposable containers for cryopreserving biopharmaceutical materials; Frames for supporting disposable containers for cryopreserving biopharmaceutical materials; Protective rigid housing structures made of plastic for receiving disposable containers for biopharmaceutical materials, non-metallic frames for supporting disposable containers for biopharmaceutical materials. Transportation carts for disposable containers for cryopreserving biopharmaceutical materials; Electric lift trucks; Mobile fork lifts. Holders therefor (containers), non-metallic; pallets, non-metallic.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
11 - Appareils de contrôle de l'environnement
12 - Véhicules; appareils de locomotion par terre, par air ou par eau; parties de véhicules
16 - Papier, carton et produits en ces matières
17 - Produits en caoutchouc ou en matières plastiques; matières à calfeutrer et à isoler
20 - Meubles et produits décoratifs
Produits et services
Containers of metal for chemicals and liquids; shipping containers of metal; packaging articles, of metal for transport and storage of goods; metal containers for holding and transporting flexible pouches for biological, medical or pharmaceutical liquids; Containers of metal for storage and transport of goods; Metal pallets; Metal racks for storage of containers filled with biopharmaceutical materials; Metallic frames for supporting disposable containers for biopharmaceutical materials Mixing machines; Mixing machines for mixing and homogenizing liquids in the pharmaceutical and chemical industries; power-operated lifting apparatus for the transport of goods, power-operated fork lifters; Packaging machines, namely, liquid container fillers; Filling machines; Machines for filling containers in the nature of disposable plastic bags with biopharmaceutical liquids; biopharmaceutical liquid dispensing machines for industrial use; Dispensing machines for emptying containers filled with biopharmaceutical liquids; pneumatic controls for machines; hydraulic controls for machines Liquid flow measuring apparatus and instruments; electrical controllers and flow regulators for industrial use; electric sensors and detectors; electrical controllers; Temperature control apparatus for chilling biopharmaceutical materials in disposable containers; Temperature controllers for controlling the temperature of biopharmaceutical materials held in disposable containers designed for cryopreservation; scientific apparatus for mixing biopharmaceutical media, in particular by vibration, rotation and wave motion; Weighing apparatus and instruments and structural parts therefor; weighing apparatus for weighing the amount of liquids filled into and dispensed from disposable containers; scientific apparatus, namely, automated liquid dispensing machines for dispensing pharmaceutical solutions; Dosage dispensers, Liquid dosage devices that measure the amounts to be dispensed Disposable containers especially made for cryopreserving biopharmaceutical materials; protective rigid housing structures for receiving disposable containers for cryopreserving biopharmaceutical materials and used as a structural component thereof; frames for supporting disposable containers for cryopreserving biopharmaceutical materials and used as a structural component thereof; storage units and transportation carts specially designed for disposable containers for cryopreserving biopharmaceutical materials; Protective devices in the nature of sleeves and frames specially designed for disposable containers for the low temperature control of biopharmaceutical materials for medical use; Disposable containers specially designed for cryopreservation of biopharmaceutical materials; Protective devices and frames for use as an integral component to secure and store disposable containers for biopharmaceutical materials Refrigerating and freezing equipment in the nature of refrigerating machines and freezers; Refrigerators, cooling apparatus and freezers for medical storage purposes; Refrigerating containers; Refrigerated shipping containers; Temperature controlled shipping containers; Refrigerated medical container for storage, transportation and cooling of medicines and pharmaceuticals; Freezing installations and machines for freezing biopharmaceutical materials; Laboratory freezers for cryogenic preservation; Heaters and heating systems comprised of heat generators for thawing frozen biopharmaceutical materials; Cooling and heating systems comprised of electric coolers and heat generators for processing biopharmaceutical materials; Containers equipped with temperature controllers for biopharmaceutical materials Transportation carts for disposable containers for cryopreserving biopharmaceutical materials; Electric lift trucks; Mobile fork lift trucks Insulated containers of cardboard for the transport and storage of temperature sensitive goods Thermal insulation covers for storage or transportation of biopharmaceutical materials Containers, and closures and holders therefor, non-metallic and non-paper; Containers, not of metal or paper, for storage or transport; Containers for biopharmaceutical liquids, non-metallic and non-paper; Packaging containers of plastic; Non-metal and non-paper insulated shipping containers for transporting frozen materials; Plastic shipping and storage boxes; crates and pallets, non-metallic; Disposable containers made of plastic for storage and transport of frozen biopharmaceutical materials; protective rigid housing structures made of plastic for receiving disposable containers for biopharmaceutical materials, Non-metallic frames for supporting disposable containers for biopharmaceutical materials; Sample bag cover specifically adapted to disposable containers for biopharmaceutical materials
09 - Appareils et instruments scientifiques et électriques
Produits et services
Packaging machines, namely, liquid container fillers; Filling machines; Machines for filling containers with biopharmaceutical liquids; Dispensing machines; Dispensing machines for emptying containers filled with biopharmaceutical liquids; Machines for filling and emptying disposable plastic bags with biopharmaceutical liquids; Fluid pumps; Pump control valves; Control devices for machines. Measuring apparatus and instruments; controllers and regulators; Sensors and detectors; Automatic control apparatus; Programmable control apparatus; Automatic control apparatus for controlling filling and dispensing machines; Automatic liquid-flow control machines and instruments; Automatic liquid-flow control machines and instruments Measuring and control devices for processing biopharmaceutical liquids; Automatic control valves; Control valves for regulating the flow of biopharmaceutical liquids; Automatic control valves for controlling the flow of biopharmaceutical liquids into and out of disposable containers; Weighing apparatus and instruments and parts therefor; weighing apparatus for weighing the amount of biopharmaceutical liquids filled into and dispensed from disposable containers; Automated liquid dispensing machines; Dosage dispensers, Liquid dosage devices that measure the amounts to be dispensed; Software for monitoring, analysing, controlling and running physical world operations; Machine control software; Process controlling software; Software for controlling and operating machines for packaging and dispensing biopharmaceutical liquids.
09 - Appareils et instruments scientifiques et électriques
Produits et services
packaging machines, namely, liquid container fillers; filling machines; machines for filling containers with biopharmaceutical liquids; biopharmaceutical liquid dispensing machines for industrial use; dispensing machines for emptying containers filled with biopharmaceutical liquids; machines for filling and emptying disposable plastic bags with biopharmaceutical liquids; electric fluid pumps; pump control valves; pneumatic controls for machines; hydraulic controls for machines measuring apparatus and instruments, namely, flowmeters; electronic controllers for the operation of liquid dispersing and filling machines; flow regulators for industrial use; electric sensors and detectors; liquid level sensors and detectors; pressure sensors and detectors; temperature sensors and detectors; sensors for measuring chemical level in aqueous solutions, not for medical use; automatic control apparatus in the nature of electrical controllers; programmable control apparatus in the nature of programmable logic controllers; automatic control apparatus in the nature of electronic controllers for operating and monitoring filling and dispensing machines; automatic liquid-flow control machines and instruments in the nature of electrical controllers; measuring and control devices for processing biopharmaceutical liquids; automatic control valves for regulating flow of liquids; control valves for regulating the flow of biopharmaceutical liquids; automatic control valves for controlling the flow of biopharmaceutical liquids into and out of disposable containers; weighing apparatus and instruments and structural parts therefor; weighing apparatus for weighing the amount of liquids filled into and dispensed from disposable containers; scientific apparatus, namely, automated liquid dispensing machines for dispensing pharmaceutical solutions; dosage dispensers, liquid dosage devices that measure the amounts to be dispensed; downloadable software for monitoring, analysing, controlling and running physical world operations; recorded software for monitoring, analysing, controlling and running physical world operations; downloadable machine control software; recorded machine control software; downloadable process controlling software; recorded process controlling software; downloadable software for controlling and operating machines for packaging and dispensing biopharmaceutical liquids; recorded software for controlling and operating machines for packaging and dispensing biopharmaceutical liquids
58.
Fluid transfer assembly, a fluid transfer system, and a related method
A fluid transfer assembly includes one or more fluid conduit and a body portion. The body portion defines a fluid channel within the body portion that is in fluid communication which each of the one or more fluid conduits when the body portion is in an elongated state. The body portion has an elongated stat in which the body portion is configured to elongate in a range of 150 percent to 1500 percent from the unelongated state without breaking to facilitate removal of a mandrel from the fluid conduit.
F16L 47/32 - Ensembles de branchement, p. ex. d'une seule pièce, soudés, rivetés
B29C 33/50 - Moules ou noyauxLeurs détails ou accessoires comportant des moyens ou conçus spécialement pour faciliter le démoulage d'objets, p. ex. des objets à contre-dépouille avec des moyens rétractables ou démontables élastiques
B29C 37/00 - Éléments constitutifs, détails, accessoires ou opérations auxiliaires non couverts par le groupe ou
B29C 39/10 - Moulage par coulée, c.-à-d. en introduisant la matière à mouler dans un moule ou entre des surfaces enveloppantes sans pression significative de moulageAppareils à cet effet pour la fabrication d'objets de longueur définie, c.-à-d. d'objets séparés en incorporant des parties ou des couches préformées, p. ex. coulée autour d'inserts ou sur des objets à recouvrir
B29C 39/34 - Moules ou noyaux pour fabriquer des objets à contre-dépouille
B29C 33/00 - Moules ou noyauxLeurs détails ou accessoires
B29C 33/12 - Moules ou noyauxLeurs détails ou accessoires comportant des moyens incorporés pour positionner des inserts, p. ex. marquages
B29C 33/44 - Moules ou noyauxLeurs détails ou accessoires comportant des moyens ou conçus spécialement pour faciliter le démoulage d'objets, p. ex. des objets à contre-dépouille
B29K 19/00 - Utilisation de caoutchouc non prévu dans un seul des groupes principaux comme matière de moulage
B29K 83/00 - Utilisation de polymères contenant dans la chaîne principale uniquement du silicium avec ou sans soufre, azote, oxygène ou carbone comme matière de moulage
B67D 7/02 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail pour transférer des liquides autres que des carburants ou des lubrifiants
59.
FREEZE/THAW CONTAINMENT SYSTEM FOR FLEXIBLE POUCH FILLED WITH BIOPHARMACEUTICAL FLUID, AND METHOD OF ASSEMBLING A FREEZE/THAW CONTAINMENT SYSTEM, USING A PROTECTING BODY
A freeze/thaw containment system is provided, having a protecting body and a flexible pouch, of a first capacity, protected by two plates of the protecting body. The two plates are attached together at a peripheral margin and form a rectangular protecting body. The peripheral margin is mounted in a stationary frame and allowed to be displaced inwardly during filling of the pouch, while the protecting body extends generally planar to sandwich and constrain the pouch. One amongst the stationary frame and the protecting body includes fastening members for attachment of a casing configured for storing the bag, in order to have the bag fastened parallel to the protecting body. Two fasteners for cooperating with the fastening members are distributed around a bag containing part of a second capacity at least ten times inferior to the first capacity. Same biopharmaceutical composition is contained in the pouch and in the bag.
B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
60.
Storage/containment unit for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body
A freeze/thaw containment system is provided, having a protecting body and a flexible pouch protected by two plates of the protecting body. The two plates are attached together at a peripheral margin and form a rectangular protecting body. The peripheral margin is mounted in supporting parts of a stationary frame and sliding positioning members are secured to the peripheral margin, so that the peripheral margin is guided and allowed to be displaced inwardly during filling of the pouch, while the protecting body extends generally planar to sandwich and constrain the pouch in empty state of the pouch. This way of holding and retaining the protecting body allows for progressive conformational change of the protecting body due to the change in volume of the pouch when filled with a biopharmaceutical product, while facilitating reverse displacement of the peripheral margin during draining operations.
Storage/containment unit for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body
A protecting device is provided, having two plates forming a rectangular protecting body for sandwiching, constraining and protecting a flexible pouch. The two plates are attached together at a peripheral margin. Each plate has an outer surface with ribs provided in a peripheral annular region of a covering part receiving the pouch, along the peripheral margin. The peripheral margin is mounted in supporting parts of a frame and sliding positioning members may be secured to the peripheral margin, so that the peripheral margin is guided and allowed to be displaced inwardly during filling of the pouch, while the protecting body extends generally planar, at least at panel parts surrounded by the ribs. This allows for progressive conformational change of the protecting body when filling the pouch with biopharmaceutical product, while facilitating reverse displacement of the peripheral margin during draining operations.
Freeze/thaw containment system for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body
A freeze/thaw containment system is provided, having a protecting body and a flexible pouch, of a first capacity, protected by two plates of the protecting body. The two plates are attached together at a peripheral margin and form a rectangular protecting body. The peripheral margin is mounted in a stationary frame and allowed to be displaced inwardly during filling of the pouch, while the protecting body extends generally planar to sandwich and constrain the pouch. One amongst the stationary frame and the protecting body includes fastening members for attachment of a casing configured for storing the bag, in order to have the bag fastened parallel to the protecting body. Two fasteners for cooperating with the fastening members are distributed around a bag containing part of a second capacity at least ten times inferior to the first capacity. Same biopharmaceutical composition is contained in the pouch and in the bag.
STORAGE/CONTAINMENT UNIT FOR FLEXIBLE POUCH FILLED WITH BIOPHARMACEUTICAL FLUID, AND METHOD OF ASSEMBLING A FREEZE/THAW CONTAINMENT SYSTEM, USING A PROTECTING BODY
A freeze/thaw containment system is provided, having a protecting body and a flexible pouch protected by two plates of the protecting body. The two plates are attached together at a peripheral margin and form a rectangular protecting body. The peripheral margin is mounted in supporting parts of a stationary frame and sliding positioning members are secured to the peripheral margin, so that the peripheral margin is guided and allowed to be displaced inwardly during filling of the pouch, while the protecting body extends generally planar to sandwich and constrain the pouch in empty state of the pouch. This way of holding and retaining the protecting body allows for progressive conformational change of the protecting body due to the change in volume of the pouch when filled with a biopharmaceutical product, while facilitating reverse displacement of the peripheral margin during draining operations.
A61M 1/02 - Appareils pour transfusion sanguine d'un corps à un autre
B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
64.
STORAGE/CONTAINMENT UNIT FOR FLEXIBLE POUCH FILLED WITH BIOPHARMACEUTICAL FLUID, AND METHOD OF ASSEMBLING A FREEZE/THAW CONTAINMENT SYSTEM, USING A PROTECTING BODY
A protecting device is provided, having two plates forming a rectangular protecting body for sandwiching, constraining and protecting a flexible pouch. The two plates are attached together at a peripheral margin. Each plate has an outer surface with ribs provided in a peripheral annular region of a covering part receiving the pouch, along the peripheral margin. The peripheral margin is mounted in supporting parts of a frame and sliding positioning members may be secured to the peripheral margin, so that the peripheral margin is guided and allowed to be displaced inwardly during filling of the pouch, while the protecting body extends generally planar, at least at panel parts surrounded by the ribs. This allows for progressive conformational change of the protecting body when filling the pouch with biopharmaceutical product, while facilitating reverse displacement of the peripheral margin during draining operations.
B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
B65D 61/00 - Châssis ou supports externes conçus pour être assemblés autour d'objets ou appliqués contre eux
B65D 81/05 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu spécialement adaptés pour protéger leur contenu des dommages mécaniques maintenant le contenu en position éloignée des parois de l'emballage ou des autres pièces du contenu
65.
System for simultaneous distribution of fluid to multiple vessels and method of using the same
A method of aseptically distributing fluid including fluidly connecting a primary vessel to a fluid distribution system via a feedline of the supply vessel to form a closed system, priming the feedline to purge trapped gases and fluid from the feedline via a purge valve, simultaneously distributing fluid from the primary vessel to a plurality of secondary vessels, sensing a complete fill of the plurality of secondary vessels with the control system, and stopping the distribution of fluid when the complete fill is sensed by the control system.
B67D 7/02 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail pour transférer des liquides autres que des carburants ou des lubrifiants
A method of aseptically distributing fluid to a plurality of vessels includes securing the plurality of vessels relative to a hub and flowing fluid through an input tube into a plenum of the hub such that a substantially equal amount of fluid flows from the plenum into each of the vessels simultaneously. The vessels are positioned in the same plane relative to one another with each vessel having an inflow conduit extending from the hub to the vessel such that an arc segment is formed between the hub and the vessel.
B67D 7/02 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail pour transférer des liquides autres que des carburants ou des lubrifiants
B67D 7/38 - Aménagements des tuyaux flexibles, p. ex. de la liaison de pilotage d'une moto-pompe
68.
STORAGE UNIT FOR USE IN FREEZING, STORING AND THAWING BIOPHARMACEUTICAL MATERIALS CONTAINED IN A FLEXIBLE POUCH AND A METHOD OF ASSEMBLING A PROTECTION SYSTEM FOR SUCH A STORAGE UNIT
A flexible pouch is placed in a stack provided with two plates forming a protecting body (12) to sandwich and constrain the pouch. At two opposite margin portions, the protecting body has slots (51, 52, 53) or interlocking members for cooperating with positioning members of an outer holding device (HR). Between lower and upper parts of the holding device, the two plates can move during filling of the pouch and the margin portions shrink inwardly in a protecting body plane. Some of the positioning members act as stoppers (41') to have lower clearance range for shrink strokes of the protecting body in a middle part thereof, as compared to a higher clearance range (X2) at respective longitudinal end parts of the margin portions. A higher constraining effect can be obtained in a center of the pouch, to limit maximum thickness of its content, which is of interest for managing freeze/thaw operations of biopharmaceutical content of the pouch.
B65D 77/06 - Liquides ou semi-liquides enfermés dans des réceptacles flexibles disposés dans des réceptacles rigides
B65D 81/38 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu avec isolation thermique
Storage/containement unit for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body of controlled deformation
A flexible pouch is placed in a stack provided with two plates forming a protecting body to sandwich and constrain the flexible pouch. At opposite margin portions, the protecting body has slots cooperating with positioning members of an outer shell device belonging to the stack. Between the shell parts, the plates can move during filling of the pouch and the margin portions shrink inwardly in a protecting body plane. Some of the positioning members act as stoppers, in order to have lower clearance range for shrink strokes of the protecting body in a middle part thereof, as compared to a higher clearance range at respective longitudinal end parts of the two opposite margin portions. A higher constraining effect can be obtained in a center of the pouch, to limit maximum thickness of its content, which is of interest for managing freeze/thaw operations of biopharmaceutical materials contained in the pouch.
A connector for facilitating fluid transfer includes first fitting, a second fitting, a rigid conduit, a first retaining connector, and a second retaining connector. The rigid conduit includes a flexible tube surrounded by a deformable sleeve. The rigid conduit is connected on a first end to the first fitting and on a second end to the second fitting. The first retaining connector connects the first fitting to the rigid conduit and the second retaining connector connects the second fitting to the rigid conduit. A lumen extends through the rigid conduit and is capable of being sealed. The rigid conduit and the flexible tube are capable of being severed while maintaining the seal of the lumen to separate the first fitting from the second fitting. The connections of the first fitting and the second fitting to the rigid conduit are capable of withstanding at least 1 bar of pressure without leaking.
A connector for facilitating fluid transfer includes first fitting, a second fitting, a rigid conduit, a first retaining connector, and a second retaining connector. The rigid conduit includes a flexible tube surrounded by a deformable sleeve. The rigid conduit is connected on a first end to the first fitting and on a second end to the second fitting. The first retaining connector connects the first fitting to the rigid conduit and the second retaining connector connects the second fitting to the rigid conduit. A lumen extends through the rigid conduit and is capable of being sealed. The rigid conduit and the flexible tube are capable of being severed while maintaining the seal of the lumen to separate the first fitting from the second fitting. The connections of the first fitting and the second fitting to the rigid conduit are capable of withstanding at least 1 bar of pressure without leaking.
A fluid transfer assembly is described that includes a fitting comprising a lumen having an opening, and at least one barb, the at least one barb extending circumferentially around the lumen proximate to the opening. The assembly also includes a flexible conduit, a deformable sleeve, and an elastomeric liner disposed between the sleeve and the conduit. The fitting extends at least partially into the conduit such that the conduit extends over the at least one barb. The elastomeric liner applies substantially 360 degree radial pressure to the conduit such that the conduit is sealingly compressed around the at least one barb of the fitting. The assembly is fluid tight up to a burst pressure of the conduit.
F16L 13/16 - Raccords de tuyaux non démontables, p. ex. raccords soudés, collés ou matés réalisés par déformation plastique du matériau du tuyau, p. ex. par déformation des brides, par laminage le raccord consistant en des extrémités se superposant et munies de collets en prise les uns avec les autres
F16L 13/14 - Raccords de tuyaux non démontables, p. ex. raccords soudés, collés ou matés réalisés par déformation plastique du matériau du tuyau, p. ex. par déformation des brides, par laminage
F16L 33/207 - Segments, manchons ou autres organes d'une seule pièce enserrant la manche ou dilatés à l'intérieur de la manche au moyen d'outilsAgencements utilisant de tels organes avec uniquement un manchon contracté sur la manche
73.
Composite articles of lattice reinforced elastomers
A composite article includes a lattice and an elastomeric section. The lattice includes a plurality of members that form an open-mesh frame defining a plurality of voids between the adjacent members of the frame. The elastomeric section is formed of an elastomer that is disposed about the lattice and within the voids of the lattice. The composite article may be a circular gasket, a gasket with a grip, a rectangular gasket, a vessel cap, a flask stand, and a handle for a hand tool.
B65D 41/00 - Capuchons, p. ex. couvercles à rebords ou capsules à sertissage, c.-à-d. éléments ayant des parties prenant sur la périphérie extérieure d'un col ou d'une paroi limitant une ouverture de versement ou de déchargeCouvercles de protection en forme de capuchons pour les éléments de fermeture, p. ex. couvercles décoratifs en feuille de métal ou en papier
B01L 9/00 - Dispositifs de supportDispositifs de serrage
B25G 1/10 - Fabrication des manches caractérisés par le matériau ou la forme
B33Y 80/00 - Produits obtenus par fabrication additive
B65D 55/00 - Accessoires pour fermetures de réceptacles non prévus ailleurs
F16J 15/02 - Joints d'étanchéité entre surfaces immobiles entre elles
F16J 15/10 - Joints d'étanchéité entre surfaces immobiles entre elles avec garniture solide comprimée entre les surfaces à joindre par garniture non métallique
B29C 45/14 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet en incorporant des parties ou des couches préformées, p. ex. moulage par injection autour d'inserts ou sur des objets à recouvrir
A flask stand is configured to support a flask and includes a base ring and a plurality of legs. The base ring is configured to support a lower portion of the flask. Each leg is secured to the base ring and extends outward from the base ring. Each leg includes a body, a lattice, and an elastomeric foot. The body includes a first end portion that is secured to the base ring with the foot portion being opposite the first end portion. The lattice is formed within the foot portion and includes a plurality of members that form an open-mesh frame that defines a plurality of voids between adjacent members of the frame. The elastomeric foot is formed of an elastomer and is disposed about the lattice and within the voids of the lattice. The foot is configured to engage a surface to support the body relative to the surface.
B29C 69/02 - Combinaisons de techniques de façonnage non prévues dans un seul des groupes principaux , p. ex. associations de techniques de moulage et d'assemblageAppareils à cet effet de techniques de moulage uniquement
B01F 11/00 - Mélangeurs avec mécanismes à secousses, oscillants ou vibrants
B01L 9/00 - Dispositifs de supportDispositifs de serrage
B29K 75/00 - Utilisation de polyurées ou de polyuréthanes comme matière de moulage
B29K 83/00 - Utilisation de polymères contenant dans la chaîne principale uniquement du silicium avec ou sans soufre, azote, oxygène ou carbone comme matière de moulage
B29K 105/00 - Présentation, forme ou état de la matière moulée
B29K 71/00 - Utilisation de polyéthers comme matière de moulage
A flask stand is configured to support a flask and includes a base ring and a plurality of legs. The base ring is configured to support a lower portion of the flask. Each leg is secured to the base ring and extends outward from the base ring. Each leg includes a body, a lattice, and an elastomeric foot. The body includes a first end portion that is secured to the base ring with the foot portion being opposite the first end portion. The lattice is formed within the foot portion and includes a plurality of members that form an open-mesh frame that defines a plurality of voids between adjacent members of the frame. The elastomeric foot is formed of an elastomer and is disposed about the lattice and within the voids of the lattice. The foot is configured to engage a surface to support the body relative to the surface.
A fluid distribution system is configured to distribute fluid from a first vessel to second vessels includes a hub assembly and a frame assembly. The hub assembly has an input cap, a distribution cap, a first clamp, and a second clamp. The input cap defines an inlet and the distribution cap is sealingly secured to the input cap with a plenum being defined between the input and distribution caps. The distribution cap includes conduit connectors that each defines an outlet in fluid communication with the plenum. The first clamp is disposed over the distribution cap and is engaged with the input cap to secure the input cap to the distribution cap and the second clamp is disposed over the input cap and engaged with the distribution cap to secure the distribution cap to the input cap. The frame assembly supports the hub assembly and is configured to secure each of the secondary vessels at a predetermined distance relative to the hub assembly.
B67C 3/22 - Mise en bouteilles de liquides ou de semi-liquidesRemplissage des bocaux ou bidons avec des liquides ou semi-liquides en utilisant des appareils de mise en bouteilles ou des appareils analogues Détails
B67C 3/24 - Dispositifs pour supporter ou tenir les bouteilles
B67C 3/26 - Têtes de remplissageDispositifs pour introduire les têtes de remplissage dans les goulots des bouteilles
77.
COMPOSITE ARTICLES OF LATTICE REINFORCED ELASTOMERS
A composite article includes a lattice and an elastomeric section. The lattice includes a plurality of members that form an open-mesh frame defining a plurality of voids between the adjacent members of the frame. The elastomeric section is formed of an elastomer that is disposed about the lattice and within the voids of the lattice. The composite article may be a circular gasket, a gasket with a grip, a rectangular gasket, a vessel cap, a flask stand, and a handle for a hand tool.
B65D 41/00 - Capuchons, p. ex. couvercles à rebords ou capsules à sertissage, c.-à-d. éléments ayant des parties prenant sur la périphérie extérieure d'un col ou d'une paroi limitant une ouverture de versement ou de déchargeCouvercles de protection en forme de capuchons pour les éléments de fermeture, p. ex. couvercles décoratifs en feuille de métal ou en papier
B33Y 80/00 - Produits obtenus par fabrication additive
F16J 15/02 - Joints d'étanchéité entre surfaces immobiles entre elles
B25G 1/10 - Fabrication des manches caractérisés par le matériau ou la forme
B01L 9/00 - Dispositifs de supportDispositifs de serrage
Method for the forming of a fluid-tight separating closure of a conduit (1) involving the following steps: - providing of a conduit (1) with a sleeve (2), - positioning of the conduit (1) with the sleeve (2) between a die (3) and a stamp (4), - compressing of the sleeve (2) by a relative movement between the die (3) and the stamp (4) in order to form a closure (5); - severing of the closure (5) in a compressed region (6) by a severing tool (7) such that a contact line (8) between the severing tool (7) and the sleeve (2) during severing is shorter than an obtained severing edge (9) of the sleeve (2).
B23D 21/00 - Machines ou dispositifs pour le cisaillage ou le tronçonnage de tubes
B29C 65/00 - Assemblage d'éléments préformésAppareils à cet effet
B23D 15/04 - Machines à cisailler ou dispositifs de cisaillage taillant au moyen de lames se déplaçant parallèlement les unes par rapport aux autres n'ayant qu'une lame mobile
79.
Vessel closures and methods for using and manufacturing same
A fluid transfer hub has a first vessel closure, a second vessel closure, a gasket arranged between the first vessel closure and the second vessel closure, and a clamp at least partially surrounding the first vessel closure, the second vessel closure, and the gasket. The first vessel closure has a first body, one or more apertures extending axially through the first body, one or more first inserts extending axially through the one or more apertures, and a cast seal disposed within the first body and surrounding each first insert. The second vessel closure has a second body, one or more apertures extending axially through the second body, one or more second inserts extending axially through the one or more apertures, and a cast seal disposed within the second body and surrounding each second insert.
B65D 47/00 - Fermetures avec dispositifs pour remplir et vider, ou pour vider
B65D 55/00 - Accessoires pour fermetures de réceptacles non prévus ailleurs
B67D 3/00 - Appareils ou dispositifs pour commander le débit du liquide à distribuer par gravité à partir des récipients de stockage
B67D 1/08 - Appareils ou dispositifs pour débiter des boissons à la pression Détails
F16L 23/16 - Raccords à brides caractérisés par les moyens d'étanchéité
B65D 53/06 - Étanchéité réalisée par matériaux liquides ou plastiques
B65D 51/24 - Fermetures non prévues ailleurs combinées avec dispositifs auxiliaires pour des buts autres que la fermeture
B65D 47/06 - Fermetures avec dispositifs de décharge autres que des pompes avec goulottes ou tubes de déversementFermetures avec dispositifs de décharge autres que des pompes avec tuyères ou passages pour la décharge
B65D 41/04 - Capuchons ou couvercles en forme de capuchons filetés ou similaires, fixés par rotation
Vessel closure assemblies are provided. The vessel closure assemblies may be engaged with vessels. The vessel closure assemblies may each include a vessel closure, inserts such as anchors and fluid conduits extending through the vessel closure, and a respiratory assembly. The respiratory assembly may include a housing and one or more gas permeable membranes. The gas permeable membranes may be oriented substantially perpendicular to a top wall of the vessel closure through which the inserts extend.
A method of aseptically distributing fluid to a plurality of vessels includes securing the plurality of vessels relative to a hub and flowing fluid through an input tube into a plenum of the hub such that a substantially equal amount of fluid flows from the plenum into each of the vessels simultaneously. The vessels are positioned in the same plane relative to one another with each vessel having an inflow conduit extending from the hub to the vessel such that an arc segment is formed between the hub and the vessel.
B67D 7/02 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail pour transférer des liquides autres que des carburants ou des lubrifiants
A method of aseptically distributing fluid to a plurality of vessels includes securing the plurality of vessels relative to a hub and flowing fluid through an input tube into a plenum of the hub such that a substantially equal amount of fluid flows from the plenum into each of the vessels simultaneously. The vessels are positioned in the same plane relative to one another with each vessel having an inflow conduit extending from the hub to the vessel such that an arc segment is formed between the hub and the vessel.
B65B 3/04 - Procédés ou moyens pour charger le matériau dans les réceptacles ou récipients
G01N 1/18 - Dispositifs pour prélever des échantillons à l'état liquide ou fluide avec mesures prises pour diviser des échantillons en plusieurs parties
A61M 39/08 - TubesMoyens de rangement spécialement adaptés aux tubes
A bioreactor for culturing of microorganisms or cells comprising: a casing defining an interior space of the bioreactor, wherein said interior space is configured to receive and hold a culture medium with microbial or cellular liquid cultures; and at least one coupling element provided on the casing for coupling with a foam mitigation device for mitigation of foam built-up in the interior space of the bioreactor during use of the bioreactor for culturing of microorganisms or cells; wherein the coupling element is configured to allow ultrasonic waves generated by the foam mitigation device act upon foam built-up in the interior space of the bioreactor.
A bioreactor for culturing of microorganisms or cells comprising: a casing defining an interior space of the bioreactor, wherein said interior space is configured to receive and hold a culture medium with microbial or cellular liquid cultures; and at least one coupling element provided on the casing for coupling with a foam mitigation device for mitigation of foam built-up in the interior space of the bioreactor during use of the bioreactor for culturing of microorganisms or cells; wherein the coupling element is configured to allow ultrasonic waves generated by the foam mitigation device act upon foam built-up in the interior space of the bioreactor.
A system for freezing, storing, transporting, and thawing biopharmaceutical product, the system including a stationary equipment and one or more movable pallet, each pallet being configured to carry one or more container units, each containing biopharmaceutical product, the stationary equipment including a gas circulating unit configured to cause a circulation of cold gas and/or warm gas, from a pull inlet toward a blow outlet, wherein there is provided at least a first side plenum having one or more gas conveying channel therein, configured to be fluidly coupled to the blow outlet of the gas circulating unit, the first side plenum having a plurality of outlet ports directed toward an interior volume of the pallet, wherein the gas circulates substantially in a horizontal direction in the interior volume of the pallet.
F25D 11/00 - Dispositifs autonomes déplaçables associés à des machines frigorifiques, p. ex. réfrigérateurs ménagers
F25D 17/06 - Dispositions pour la circulation des fluides de refroidissementDispositions pour la circulation de gaz, p. ex. d'air, dans les enceintes refroidies pour la circulation de gaz, p. ex. convection naturelle par circulation d'air forcée
F25D 25/02 - Introduction, port ou déchargement des produits à refroidir par étagères
86.
RAPID FREEZING, STORAGE, TRANSPORT, AND THAWING SYSTEM FOR CONTAINERS OF BIOPHARMACEUTICAL PRODUCTS
A system for freezing, storing, transporting, and thawing biopharmaceutical product includes a stationary equipment and one or more movable pallet (2), each pallet being configured to carry one or more container units containing biopharmaceutical product, the stationary equipment including a gas circulating unit configured to cause a circulation of cold gas and/or warm gas, from a pull inlet toward a blow outlet, wherein there is provided at least a first side plenum (31) having one or more gas conveying channel therein, configured to be fluidly coupled to the blow outlet of the gas circulating unit, the first side plenum having a plurality of outlet ports (33) directed toward an interior volume of the pallet, wherein the gas circulates substantially in a horizontal direction in the interior volume of the pallet. The container units may be bag assemblies, each comprising a single-use flexible bag (5) and a protective packaging.
Fluid transfer assemblies for transferring fluid into or out of a single vessel and distributing the fluid to multiple other vessels are provided. The fluid transfer assemblies are customizable, substantially aseptic, and single-use. The fluid transfer assemblies may be manufactured by solidifying polymeric materials to form a body around a mandrel with protrusions engaged to fluid conduits and leaving recesses in the solidified polymeric material to stretch the resultant body and remove the mandrel with protrusions. The resultant fluid transfer assembly may be surrounded by a rigid housing and valves may be engaged with the conduits and/or body to control the fluid flow within the fluid transfer assembly.
B29C 37/00 - Éléments constitutifs, détails, accessoires ou opérations auxiliaires non couverts par le groupe ou
B67D 7/02 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail pour transférer des liquides autres que des carburants ou des lubrifiants
B29C 33/50 - Moules ou noyauxLeurs détails ou accessoires comportant des moyens ou conçus spécialement pour faciliter le démoulage d'objets, p. ex. des objets à contre-dépouille avec des moyens rétractables ou démontables élastiques
B29C 65/70 - Assemblage d'éléments préformésAppareils à cet effet par moulage
B29C 39/10 - Moulage par coulée, c.-à-d. en introduisant la matière à mouler dans un moule ou entre des surfaces enveloppantes sans pression significative de moulageAppareils à cet effet pour la fabrication d'objets de longueur définie, c.-à-d. d'objets séparés en incorporant des parties ou des couches préformées, p. ex. coulée autour d'inserts ou sur des objets à recouvrir
B29C 39/34 - Moules ou noyaux pour fabriquer des objets à contre-dépouille
B29C 33/12 - Moules ou noyauxLeurs détails ou accessoires comportant des moyens incorporés pour positionner des inserts, p. ex. marquages
B29C 33/44 - Moules ou noyauxLeurs détails ou accessoires comportant des moyens ou conçus spécialement pour faciliter le démoulage d'objets, p. ex. des objets à contre-dépouille
B29K 83/00 - Utilisation de polymères contenant dans la chaîne principale uniquement du silicium avec ou sans soufre, azote, oxygène ou carbone comme matière de moulage
A fluid transfer assembly is described that includes a fitting comprising a lumen having an opening, and at least one barb, the at least one barb extending circumferentially around the lumen proximate to the opening. The assembly also includes a flexible conduit, a deformable sleeve, and an elastomeric liner disposed between the sleeve and the conduit. The fitting extends at least partially into the conduit such that the conduit extends over the at least one barb. The elastomeric liner applies substantially 360 degree radial pressure to the conduit such that the conduit is sealingly compressed around the at least one barb of the fitting. The assembly is fluid tight up to a burst pressure of the conduit.
F16L 33/22 - Dispositions d'assemblage des manches avec des organes rigidesRaccords rigides pour manches, p. ex. éléments unitaires s'engageant à la fois dans deux manches avec moyens non mentionnés dans les groupes précédents pour saisir la manche entre l'extérieur et l'intérieur
F16L 13/00 - Raccords de tuyaux non démontables, p. ex. raccords soudés, collés ou matés
F16L 13/14 - Raccords de tuyaux non démontables, p. ex. raccords soudés, collés ou matés réalisés par déformation plastique du matériau du tuyau, p. ex. par déformation des brides, par laminage
F16L 19/00 - Raccords dans lesquels les surfaces d'étanchéité sont maintenues en contact par un organe, p. ex. un écrou à oreilles vissé dans, ou vissé sur une des parties du raccord
F16L 19/04 - Raccords dans lesquels les surfaces d'étanchéité sont maintenues en contact par un organe, p. ex. un écrou à oreilles vissé dans, ou vissé sur une des parties du raccord utilisant des segments rigides additionnels, scellés directement à une extrémité du tuyau au moins, cette extrémité étant rabattue soit avant, soit pendant l'opération d'assemblage
F16L 33/00 - Dispositions d'assemblage des manches avec des organes rigidesRaccords rigides pour manches, p. ex. éléments unitaires s'engageant à la fois dans deux manches
F16L 33/20 - Segments, manchons ou autres organes d'une seule pièce enserrant la manche ou dilatés à l'intérieur de la manche au moyen d'outilsAgencements utilisant de tels organes
Cell separation systems, and methods for separating cells from microcarriers, and harvesting the separated cells, are provided, wherein the system comprises a cell separation device, a cell settling device, and a cell screening device.
A fluid transfer assembly is described. The fluid transfer assembly includes a unitary junction having an upstream portion and a downstream portion, the unitary junction defining a plurality of curved fluid pathways between the upstream portion and the downstream portion. The assembly also includes at least one flexible fluid conduit sealed to the junction in fluid communication with at least one of the plurality of curved fluid pathways.
B65B 3/00 - Emballage de matériaux plastiques, de semi-liquides, de liquides ou de liquides et solides mélangés, dans des réceptacles ou récipients individuels, p. ex. dans des sacs ou sachets, boîtes, cartons, bidons ou pots
B65B 3/04 - Procédés ou moyens pour charger le matériau dans les réceptacles ou récipients
A fluid transfer assembly is described. The fluid transfer assembly includes a unitary junction having an upstream portion and a downstream portion, the unitary junction defining a plurality of curved fluid pathways between the upstream portion and the downstream portion. The assembly also includes at least one flexible fluid conduit sealed to the junction in fluid communication with at least one of the plurality of curved fluid pathways.
A protecting system for containing a biopharmaceutical fluid includes: a flexible pouch designed to contain a biopharmaceutical fluid; a protecting package including: two frames which respectively form a lower frame and an upper frame and which have a peripheral area; a fastening system able to clamp the two frames of the protecting package to each other, the frames sandwiching the flexible pouch. The fastening system includes at least an assembly only including: a snap including a backing part; and a cap including a washer. The lower and the upper frames of the protecting package are directly clamped between the washer of the cap and the backing part of the snap in a clamping position.
B65D 81/02 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu spécialement adaptés pour protéger leur contenu des dommages mécaniques
F16B 43/00 - Rondelles ou dispositifs équivalentsAutres dispositifs de support pour têtes de boulons ou d'écrous
A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet
F16B 21/08 - Dispositifs de fixation largables à action rapide dans lesquels la broche ou l'ergot ont une partie élastique
F16B 19/00 - Chevilles à têteGoupilles, y compris celles réalisées par déformation d'élémentsRivets
93.
PROTECTING SYSTEM FOR CONTAINING A BIOPHARMACEUTICAL FLUID
Protecting system (10) for containing a biopharmaceutical fluid comprising: a flexible pouch (14) designed to contain a biopharmaceutical fluid a protecting package (112) comprising two frames (112A, 112B) which respectively form a lower frame and an upper frame and which have a peripheral area a fastening system (200) able to clamp the two frames (112A, 112B) of the protecting package (112) to each other, the frames (112A, 112B) sandwiching the flexible pouch (14) said fastening system (200) comprising at least an assembly (202) only comprising: a snap (210) comprising a backing part (212), and a cap (220) comprising a washer (222). The lower and the upper frames (112A, 112B) of the protecting package (112) are directly clamped between the washer (222) of the cap (220) and the backing part (212) of the snap (210) in a clamping position.
Disclosed is a method and system for freezing a biopharmaceutical fluid which is hold in a disposable container. The method includes the steps of arranging the container on the heat transfer surface area, cooling the heat transfer surface area to cool the bottom surface of the container until freezing and forming a layer of ice or an ice block of biopharmaceutical fluid inside the container; dislodging the ice layer or ice block frozen to the container. The steps of cooling the heat transfer surface area and dislodging the ice layer or ice block are repeated until the container is filled with a matrix of frozen biopharmaceutical fluid and liquid biopharmaceutical fluid, the liquid biopharmaceutical fluid occupying interstitial passages between ice layers or ice blocks of biopharmaceutical fluid. The cooling is then maintained until the freezing of the entire biopharmaceutical fluid held in the container.
A fluid transfer hub has a first vessel closure, a second vessel closure, a gasket arranged between the first vessel closure and the second vessel closure, and a clamp at least partially surrounding the first vessel closure, the second vessel closure, and the gasket. The first vessel closure has a first body, one or more apertures extending axially through the first body, one or more first inserts extending axially through the one or more apertures, and a cast seal disposed within the first body and surrounding each first insert. The second vessel closure has a second body, one or more apertures extending axially through the second body, one or more second inserts extending axially through the one or more apertures, and a cast seal disposed within the second body and surrounding each second insert.
B65D 53/06 - Étanchéité réalisée par matériaux liquides ou plastiques
B65D 51/24 - Fermetures non prévues ailleurs combinées avec dispositifs auxiliaires pour des buts autres que la fermeture
B65D 47/06 - Fermetures avec dispositifs de décharge autres que des pompes avec goulottes ou tubes de déversementFermetures avec dispositifs de décharge autres que des pompes avec tuyères ou passages pour la décharge
B65D 41/04 - Capuchons ou couvercles en forme de capuchons filetés ou similaires, fixés par rotation
Fluid transfer assemblies (100, 200) for transferring fluid into or out of a single vessel and distributing the fluid to multiple other vessels are provided. The fluid transfer assemblies are customizable, substantially aseptic, and single-use. The fluid transfer assemblies may be manufactured by solidifying polymeric materials to form a body around a mandrel with protrusions engaged to fluid conduits and leaving recesses in the solidified polymeric material to stretch the resultant body and remove the mandrel with protrusions. The resultant fluid transfer assembly may be surrounded by a rigid housing (130, 230) and valves (140, 240) may be engaged with the conduits (110, 210) and/or body to control the fluid flow within the fluid transfer assembly.
B29C 33/48 - Moules ou noyauxLeurs détails ou accessoires comportant des moyens ou conçus spécialement pour faciliter le démoulage d'objets, p. ex. des objets à contre-dépouille avec des moyens rétractables ou démontables
B67D 7/00 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail
B67D 7/02 - Appareils ou dispositifs pour transférer des liquides à partir de récipients ou de réservoirs de stockage en vrac vers des véhicules ou des récipients portables, p. ex. pour la vente au détail pour transférer des liquides autres que des carburants ou des lubrifiants
B67D 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
B29C 33/00 - Moules ou noyauxLeurs détails ou accessoires
B29C 33/50 - Moules ou noyauxLeurs détails ou accessoires comportant des moyens ou conçus spécialement pour faciliter le démoulage d'objets, p. ex. des objets à contre-dépouille avec des moyens rétractables ou démontables élastiques
97.
A FLUID TRANSFER ASSEMBLY, A FLUID TRANSFER SYSTEM, AND A RELATED METHOD
Fluid transfer assemblies for transferring fluid into or out of a single vessel and distributing the fluid to multiple other vessels are provided. The fluid transfer assemblies are customizable, substantially aseptic, and single-use. The fluid transfer assemblies may be manufactured by solidifying polymeric materials to form a body around a mandrel with protrusions engaged to fluid conduits and leaving recesses in the solidified polymeric material to stretch the resultant body and remove the mandrel with protrusions. The resultant fluid transfer assembly may be surrounded by a rigid housing and valves may be engaged with the conduits and/or body to control the fluid flow within the fluid transfer assembly.
A fluid transport apparatus defining an aseptic pathway configured to direct fluids therethrough is provided. The fluid transport apparatus may include a conduit extending between a first terminus and a second terminus. The conduit may include platinum catalyzed silicone rubber having methyl and phenyl side groups. The conduit may have a storage modulus of 108 or less Pascals at -75 degrees Celsius. At least one fitting may be connected to the first terminus. A fluid storage accessory may be engaged with the second terminus. A related flexible conduit, method of manufacturing a flexible conduit, and storage method are also provided.
8 or less Pascals at −75 degrees Celsius. At least one fitting may be connected to the first terminus. A fluid storage accessory may be engaged with the second terminus. A related flexible conduit, method of manufacturing a flexible conduit, and storage method are also provided.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Scientific apparatus and instruments for the separation and
treatment of biological materials, namely, cells, organisms,
and cellular components and media.
