Goods & Services

Contract manufacturing of pharmaceutical products; contract manufacturing of pre-filled syringes containing pharmaceutical preparations; manufacture, for others, of pharmaceutical and biopharmaceutical preparations; Manufacture for others of pharmaceuticals; manufacture for others of products relating to biotechnology; manufacture for others of cell therapy products; manufacture for others of gene therapy products; pharmaceutical manufacturing in accordance with GMP regulations. Pharmaceutical research services; research and development of pharmaceutical products; development of products; Contract development and manufacturing organization (CDMO) services; consulting and advisory services in the field of analytical development and quality control testing of pharmaceutical, gene therapy, and cell therapy products; consulting and advisory services in the field of manufacturing process development for pharmaceutical, gene therapy and cell therapy products; consulting in the field of chemistry manufacturing and controls (CMC) activities; testing of pharmaceutical, gene therapy, and cell therapy products and materials; quality control testing of pharmaceutical products and materials; testing and validation services for pharmaceutical, cell therapy and gene therapy methods of development.

Abstract

A transfer device (10) for removing or transferring a medium out of or into a bottle (20) having a bottle neck (34) that can be closed by means of a closure (42), including a first adapter part (12), which can be positioned on the bottle, and a second adapter part (14), which interacts with the first adapter part, which can be displaced in the longitudinal direction of the bottle, and has a conducting element (50) for piercing the closure. After the second adapter part (14) has been displaced along the first adapter part in the direction of the closure (42) and the second adapter part has been locked, the first adapter part (12) is non-releasably fastened to or around the bottle (20).

IPC Classes  ?

• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
• A61J 1/16 - Holders for containers

Abstract

Disclosed is a process for preparing new crystal salt forms of sulfasalazine, in particular a crystal Form A of the D(−)-N-methylglucamine (meglumine) salt of sulfasalazine, a crystal form A of the piperazine salt of sulfasalazine and a crystal Form B of the diethylamine salt of sulfasalazine, and the use thereof in the treatment of a disease or condition in which modulation of inflammatory cells is beneficial, a disease or condition concerning bones or joints and/or the gastro-intestinal tract.

IPC Classes  ?

• A61K 31/4402 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• C07D 213/76 - Nitrogen atoms to which a second hetero atom is attached

Goods & Services

Pharmaceuticals; Pharmaceuticals and natural remedies. Medical apparatus and instruments; Equipment, containers and bags for the reconstitution of medicinal products for intravesical use.

Goods & Services

Pharmaceutical preparations for conditioning therapy prior hematopoietic stem cell transplantation

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceuticals.

Goods & Services

Downloadable and recorded content; Computer databases; Software; Application software; apps; Web application and server software; Information technology and audio-visual, multimedia and photographic devices; Apparatus, instruments and cables for electricity; Scientific research and laboratory apparatus, educational apparatus and simulators. Human healthcare services; Medical services; Pharmaceutical services; Mental health services; Human hygiene and beauty care.

Abstract

The present invention relates to a pressure measuring device (10) including an elastic body (12) having a wall (14) which defines a lumen (16) arranged within the elastic body (12), the lumen (16) being fillable with a compressible fluid. The lumen (16) is configured to be compressed by a body part of a user to compress the compressible fluid. A pressure detection device (20) is configured to detect a pressure in the lumen (16). The pressure measuring device (10) further includes a connection member (24) arranged within an opening (26) formed in and attached to the wall (14), the connection member (24) being operatively connectable to an electrical component (20, 28) of the pressure measuring device (10) and connectable to an external power source (30). The connection member (24) has an outer contour (32) which is curved, with respect to a direction which extends along a longitudinal axis (34) of the opening (26), at an interface (36) between the wall (14) and the connection member (24).

IPC Classes  ?

• G01L 1/02 - Measuring force or stress, in general by hydraulic or pneumatic means
• A61B 5/22 - ErgometryMeasuring muscular strength or the force of a muscular blow

Goods & Services

Pharmaceutical preparations.

Abstract

The present invention relates to a pressure measuring device (100; 200) for monitoring a medical condition of a user related to arthritis and/or arthrosis. The pressure measuring device (100; 200) comprises an elastic body (102; 202) defining a lumen (104; 204) filled with a compressible fluid. The lumen (104; 204) is configured to be compressed by at least one body part of a user. The pressure measuring device (100; 200) further comprises a pressure detection device (112; 212) arranged at least partially within the lumen (104; 204), the pressure detection device (112; 212) being configured to detect at least one absolute pressure in the lumen (104; 204), generate a pressure signal based on the detected absolute pressure, and provide the pressure signal to an evaluating device (114) for evaluating the pressure signal. The pressure measuring device (100; 200) further comprises an energy source arranged within the elastic body (102; 202).

IPC Classes  ?

• A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
• A61B 5/22 - ErgometryMeasuring muscular strength or the force of a muscular blow

Abstract

Disclosed is a process for preparing new crystal salt forms of sulfasalazine, in particular a crystal Form A of the D(−)-N-methylglucamine (meglumine) salt of sulfasalazine, a crystal form A of the piperazine salt of sulfasalazine and a crystal Form B of the diethylamine salt of sulfasalazine, and the use thereof in the treatment of a disease or condition in which modulation of inflammatory cells is beneficial, a disease or condition concerning bones or joints and/or the gastro-intestinal tract.

IPC Classes  ?

• A61K 31/4402 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• C07D 213/76 - Nitrogen atoms to which a second hetero atom is attached

Goods & Services

Recorded content; Databases; Software; Application software; apps; Web application and server software; Information technology and audio-visual, multimedia and photographic devices; Apparatus, instruments and cables for electricity; Scientific research and laboratory apparatus, educational apparatus and simulators. Physical therapy equipment; Medical and veterinary apparatus and instruments; Mobility aids. IT services; Science and technology services; Testing, authentication and quality control; Design services. Human healthcare services; Human hygiene and beauty care.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceuticals.

Abstract

A lyophilisate of treosulfan is described which possesses favourable characteristics in terms of a short reconstitution time and a high purity and stability and which is particularly useful in the treatment of cancer and for conditioning therapy before transplantation of bone marrow or blood stem cells.

IPC Classes  ?

• A61K 9/19 - Particulate form, e.g. powders lyophilised
• C07C 309/08 - Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton containing hydroxy groups bound to the carbon skeleton

Abstract

A crystalline form of treosulfan and methods to prepare it are described. This crystalline form of treosulfan is useful in pharmaceutical compositions for the treatment of cancer and for conditioning therapy before transplantation of bone marrow or blood stem cells.

IPC Classes  ?

• C07C 309/66 - Methanesulfonates
• A61K 9/19 - Particulate form, e.g. powders lyophilised

Abstract

Disclosed is to a new pharmaceutical composition for oral administration containing sulfasalazine and/or a sulfasalazine organic salt, production processes and uses, in particular in the treatment of a disease or condition in which modulation of inflammatory cells is beneficial, a disease or condition concerning bones or joints and/or the gastro-intestinal tract.

IPC Classes  ?

• A61K 31/655 - Azo (—N=N—), diazo (=N2), azoxy (N—O—N or N(=O)—N), azido (—N3) or diazoamino (—N=N—N) compounds
• A61K 33/242 - GoldCompounds thereof
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/20 - Pills, lozenges or tablets
• A61K 9/28 - DrageesCoated pills or tablets
• A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
• A61K 9/50 - Microcapsules
• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
• A61K 31/405 - Indole-alkanecarboxylic acidsDerivatives thereof, e.g. tryptophan, indomethacin
• A61K 31/415 - 1,2-Diazoles
• A61K 31/42 - Oxazoles
• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
• A61K 31/58 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
• A61K 31/616 - Salicylic acidDerivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
• A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceuticals.

Abstract

Disclosed are a process for preparing new crystal salt forms of sulfasalazine, in particular crystal Form A of the D(−)-N-methylglucamine (meglumine) salt of sulfasalazine (see FIG. 1), crystal form A of the piperazine salt of sulfasalazine (see FIG. 2) and crystal Form B of the diethylamine salt of sulfasalazine (see FIG. 4), and a pharmaceutical composition containing one or more of the inventive crystal salt forms in particular in the treatment of a disease or condition in which modulation of inflammatory cells is beneficial, a disease or condition concerning bones or joints and/or the gastro-intestinal tract.

IPC Classes  ?

• A61K 31/4402 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• C07D 213/76 - Nitrogen atoms to which a second hetero atom is attached

Goods & Services

Medicines and pharmaceutical preparations; Veterinary preparations; Chemicals for medical use; Sanitary preparations for medical purposes; Sanitary preparations for medical purposes; Foodstuffs and dietetic substances for medical or veterinary purposes; Infant formula; Dietary supplements for humans; Dietary supplements for animals; Plasters, materials for dressings; Dressings, medical; Teeth filling material; Dental impression materials; Disinfectants; Fungicides; Herbicides; Vermin destroying preparations.

Goods & Services

Medicines and pharmaceutical preparations; Veterinary preparations; Chemicals for medical use; Sanitary preparations for medical purposes; Sanitary preparations for medical purposes; Foodstuffs and dietetic substances for medical or veterinary purposes; Infant formula; Dietary supplements for humans; Dietary supplements for animals; Plasters, materials for dressings; Dressings, medical; Teeth filling material; Dental impression materials; Disinfectants; Fungicides; Herbicides; Vermin destroying preparations.

Goods & Services

(1) Pharmaceutical preparations for Conditioning Therapy prior to Hematopoietic Stem Cell Transplantation

Goods & Services

Medicine.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceuticals.

Abstract

A transfer device (10) for removing or transferring a medium out of or into a bottle (20) having a bottle neck (34) that can be closed by means of a closure (42), including a first adapter part (12), which can be positioned on the bottle, and a second adapter part (14), which interacts with the first adapter part, which can be displaced in the longitudinal direction of the bottle, and has a conducting element (50) for piercing the closure. After the second adapter part (14) has been displaced along the first adapter part in the direction of the closure (42) and the second adapter part has been locked, the first adapter part (12) is non-releasably fastened to or around the bottle (20).

IPC Classes  ?

• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
• A61J 1/16 - Holders for containers
• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe

Abstract

A process is described for the preparation of freeze-dried pharmaceutical compositions of mitomycin C, which are characterized by high stability and can be rapidly reconstituted to form solutions.

IPC Classes  ?

• A61K 9/19 - Particulate form, e.g. powders lyophilised
• A61K 31/435 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
• A61K 9/08 - Solutions
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Goods & Services

(1) Pharmaceutical preparations for Conditioning Therapy prior Hematopoietic Stem Cell Transplantation

Abstract

A crystalline form of treosulfan and methods to prepare it are described. This crystalline form of treosulfan is useful in pharmaceutical compositions for the treatment of cancer and for conditioning therapy before transplantation of bone marrow or blood stem cells.

IPC Classes  ?

• A61P 35/00 - Antineoplastic agents
• C07C 309/66 - Methanesulfonates
• A61K 31/00 - Medicinal preparations containing organic active ingredients

Abstract

A solution is described which comprises treosulfan and a mixture of water and acetic acid and leads, upon freeze-drying, to a lyophilisate which possesses favourable characteristics in terms of a short reconstitution time and a high purity and stability and which is particularly useful in the treatment of cancer and for conditioning therapy before transplantation of bone marrow or blood stem cells.

IPC Classes  ?

• A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
• A61K 9/08 - Solutions
• A61K 9/19 - Particulate form, e.g. powders lyophilised
• A61K 31/255 - Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof

Abstract

A lyophilisate of treosulfan is described which possesses favourable characteristics in terms of a short reconstitution time and a high purity and stability and which is particularly useful in the treatment of cancer and for conditioning therapy before transplantation of bone marrow or blood stem cells.

IPC Classes  ?

• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 9/19 - Particulate form, e.g. powders lyophilised

Goods & Services

Pharmaceutical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic foodstuffs and substances adapted for medical use; Infant formula; Dietary supplements for humans; Plasters, materials for dressings; Dressings, medical; Teeth filling material; Dental impression materials; Disinfectants.

Abstract

The present invention relates to a new pharmaceutical composition for oral administration containing sulfasalazine and/or a sulfasalazine organic salt, production processes and uses,in particular in the treatment of a disease or condition in which modulation of inflammatory cells is beneficial, a disease or condition concerning bones or joints and/or the gastro-intestinal tract.

IPC Classes  ?

• A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
• A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
• A61K 9/08 - Solutions
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Abstract

The present invention relates to new crystal salt forms of sulfasalazine, in particular crystal Form A of the D(-)-N-methylglucamine (meglumine) salt of sulfasalazine (see Figure 1), crystal form A of the piperazine salt of sulfasalazine (see Figure 2) and crystal Form B of the diethylamine salt of sulfasalazine (see Figure 4), which can be obtained by use of the inventive preparation pro- cess, a pharmaceutical composition comprising one or more of the inventive crystal salt forms in particular in the treatment of a disease or condition in which modulation of inflammatory cells is beneficial, a disease or condition concerning bones or joints and/or the gastro-intestinal tract.

IPC Classes  ?

• C07D 213/76 - Nitrogen atoms to which a second hetero atom is attached

Goods & Services

Computer software; Interactive computer systems. Educational instruction. Advisory services relating to computer programming; Computer software research; Software development. Medical services; Medical consultations; Medical services for the diagnosis of conditions of the human body; Professional consultancy relating to health care; Monitoring of patients; Professional consultancy relating to health; Advisory services relating to health.

Goods & Services

Pharmaceutical preparations for conditioning therapy prior hematopoietic stem cell transplantation

Goods & Services

Pharmaceutical preparations.

Goods & Services

Pharmaceuticals; Medical preparations.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceutical preparations; medicines; chemical preparations for medical purposes; plasters, materials for dressing; disinfectants.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceutical products.

Goods & Services

Pharmaceuticals; Veterinary preparations; Sanitary preparations for medical purposes; Foodstuffs and dietetic substances for medical or veterinary purposes; Infant formula; Dietary supplements for humans; Dietary supplements for animals; Plasters, materials for dressings; Dressings, medical; Teeth filling material; Dental impression materials; Disinfectants; Fungicides; Herbicides; Preparations for destroying vermin.

Goods & Services

Pharmaceuticals; Veterinary preparations; Sanitary preparations for medical purposes; Foodstuffs and dietetic substances for medical or veterinary purposes; Infant formula; Dietary supplements for humans; Dietary supplements for animals; Plasters, materials for dressings; Dressings, medical; Teeth filling material; Dental impression materials; Disinfectants; Fungicides; Herbicides; Preparations for destroying vermin.

Goods & Services

Pharmaceuticals; Veterinary preparations; Sanitary preparations for medical purposes; Foodstuffs and dietetic substances for medical or veterinary purposes; Infant formula; Dietary supplements for humans; Dietary supplements for animals; Plasters, materials for dressings; Dressings, medical; Teeth filling material; Dental impression materials; Disinfectants; Fungicides; Herbicides; Preparations for destroying vermin.

Abstract

A method for purifying epidaunorubicin is provided. The purification method involves the removal of the impurity epi-feudomycin, which is formed as a by-product in the biotechnological production of epidaunorubicin.

IPC Classes  ?

• C07H 15/252 - Naphthacene radicals, e.g. daunomycins, adriamycins
• C07H 1/06 - SeparationPurification
• C07H 15/24 - Condensed ring systems having three or more rings

Abstract

A transfer device (10) for removing or transferring a medium out of or into a bottle (20) having a bottle neck (34) that can be closed by means of a closure (42), including a first adapter part (12), which can be positioned on the bottle, and a second adapter part (14), which interacts with the first adapter part, which can be displaced in the longitudinal direction of the bottle, and has a conducting element (50) for piercing the closure. After the second adapter part (14) has been displaced along the first adapter part in the direction of the closure (42) and the second adapter part has been locked, the first adapter part (12) is non-releasably fastened to or around the bottle (20).

IPC Classes  ?

• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
• A61J 1/16 - Holders for containers

Abstract

A process is described for the preparation of freeze-dried pharmaceutical compositions of mitomycin C, which are characterized by high stability and can be rapidly reconstituted to form solutions.

IPC Classes  ?

• A61K 31/435 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
• A61K 9/19 - Particulate form, e.g. powders lyophilised
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
• A61K 9/08 - Solutions
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Goods & Services

Pharmaceuticals.

Goods & Services

(1) Pharmaceutical preparations for treating cancer and auto-immune diseases; medicines for treating cancer and auto-immune diseases; chemical preparations for medical purposes, namely, chemical reagents for diagnostic purposes; medical plasters; surgical dressings; all purpose disinfectants.

Goods & Services

Pharmaceutical preparations; Veterinary preparations; Sanitary preparations for medical purposes; Foodstuffs and dietetic substances for medical or veterinary purposes; Infant formula; Dietary supplements for humans; Dietary supplements for animals; Plasters, materials for dressings; Dressings, medical; Teeth filling material; Dental impression materials; Disinfectants; Fungicides; Herbicides; Preparations for destroying vermin.

Goods & Services

Pharmaceutical preparations; Veterinary preparations; Sanitary preparations for medical purposes; Foodstuffs and dietetic substances for medical or veterinary purposes; Infant formula; Dietary supplements for humans; Dietary supplements for animals; Plasters, materials for dressings; Dressings, medical; Teeth filling material; Dental impression materials; Disinfectants; Fungicides; Herbicides; Preparations for destroying vermin.

Abstract

The present invention relates to a method for purifying epidaunorubicin, in particular to the removal of the impurity epi-feudomycin such as is formed as a by-product in the biotechnological production of epidaunorubicin.

IPC Classes  ?

• C07H 15/24 - Condensed ring systems having three or more rings

Abstract

The invention relates to a transfer device (10) for removing or transferring a medium out of or into a bottle (20) having a bottle neck (34) that can be closed by means of a closure (42), comprising a first adapter part (12), which can be positioned on the bottle, and a second adapter part (14), which interacts with the first adapter part, can be displaced in the longitudinal direction of the bottle, and has a conducting element (50) for piercing the closure. After the second adapter part (14) has been displaced along the first adapter part in the direction of the closure (42) and the second adapter part has been locked, the first adapter part (12) is non-releasably fastened to or around the bottle (20).

IPC Classes  ?

• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe

Abstract

The invention relates to a transfer device for tapping or delivering a fluid from a bottle sealed with a closure, the device having a hollow cylinder-shaped first part having a circumferential wall, which first part can be placed on the bottle and surrounds the closure, a hollow cylinder-shaped second part which can be adjusted with respect to the first part, the second part having a first wall running transverse to the longitudinal axis direction, and a puncturing needle originating from the first wall and extending in the direction of the first part permitting piercing of the closure, wherein the first part cannot be adjusted axially with respect to the second part if the closure is not surrounded and, if the first part surrounds the closure, the first part can be adjusted with respect to the second part for piercing the closure.

IPC Classes  ?

• A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor

Goods & Services

Pharmaceutical preparations for treating autoimmune diseases and oncological diseases.

Abstract

The invention relates to a method for producing freeze-dried mitomycin C compositions which have excellent stability and can be quickly reconstituted to solutions.

IPC Classes  ?

• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 9/08 - Solutions
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 9/19 - Particulate form, e.g. powders lyophilised
• A61K 31/00 - Medicinal preparations containing organic active ingredients

Goods & Services

(1) Pharmaceutical preparations for treating and diagnosing cancer, autoimmune diseases, urologic diseases; pharmaceutical preparations for use in fibrinolysis and hematology; prescription pharmaceutical preparations for use in dermatology; pharmaceutical preparations for detecting cancers and autoimmune diseases. (2) Surgical instruments designed to treat, diagnose or alleviate disease or disease symptoms in humans in the field of oncology, autoimmune diseases, urology, fibrinolysis, hematology and dermatology.

Abstract

5 straight and branched alcohols and mixtures thereof, wherein solvent C is selected to provide lower solubility to 4′-epidaunorubicin hydrochloride than solvent B. A method of producing an anthracycline using crystalline 4′-epidaunorubicin hydrochloride is also provided.

IPC Classes  ?

• C07H 15/24 - Condensed ring systems having three or more rings
• C07H 15/252 - Naphthacene radicals, e.g. daunomycins, adriamycins
• C07H 1/00 - Processes for the preparation of sugar derivatives

Goods & Services

Pharmaceutical preparations.

Abstract

The present invention relates to a pharmaceutical composition according to the invention containing 14 to 17.5 mg leflunomide prepared as a single dose and uses thereof.

IPC Classes  ?

• A61K 31/42 - Oxazoles
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection

Abstract

5 straight and branched alcohols and mixtures thereof, wherein solvent C is selected to provide lower solubility to 4′-epidaunorubicin hydrochloride than solvent B. A method of producing an anthracycline using crystalline 4′-epidaunorubicin hydrochloride is also provided.

IPC Classes  ?

• C07H 15/24 - Condensed ring systems having three or more rings

Goods & Services

Pharmaceutical preparations.

Abstract

The invention relates to a transfer device (10) for tapping or delivering a fluid from a bottle (24) sealed with a closure (26, 28), said device comprising a hollow cylinder-shaped first part (12) having a circumferential wall (16), which first part (12) can be placed on the bottle and surrounds the closure (26, 28), a hollow cylinder-shaped second part (14) which can be adjusted with respect to the first part (12), said second part having a first wall (46) running transverse to the longitudinal axis direction, and a puncturing needle (48) originating from the first wall (46) and extending in the direction of the first part permitting piercing of the closure (26, 28), wherein the first part (12) cannot be adjusted axially with respect to the second part if the closure (26, 28) is not surrounded and, if the first part (12) surrounds the closure (26 28), the first part (12) can be adjusted with respect to the second part (14) for piercing the closure (26, 28). To prevent any injury from the puncturing needle (48), according to the invention the first part (12) has a second wall (30) running transverse to the longitudinal axis (80) of the first part (12) and the distal end (74) of the puncturing needle (48) runs between the first and the second wall (30, 46) if the first and the second parts (12, 14) cannot be axially adjusted or largely cannot be axially adjusted with respect to one another.

IPC Classes  ?

• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe

Goods & Services

Pharmaceutical preparations.

Goods & Services

Pharmaceutical preparations.

Abstract

A crystalline epirubicin hydrochloride and a method for its production are provided. The method for producing the crystalline epirubicin hydrochloride includes the steps: (a) providing epirubicin hydrochloride, (b) producing a mixture containing the provided epirubicin hydrochloride and at least one alcohol selected from the group 1-butanol, 2-butanol, and 1-pentanol, and (c) crystallizing epirubicin hydrochloride from this mixture.

IPC Classes  ?

• C07H 15/252 - Naphthacene radicals, e.g. daunomycins, adriamycins
• C07H 1/06 - SeparationPurification

Abstract

5 straight and branched alcohols and mixtures thereof, wherein solvent C is selected to provide lower solubility to 4′-epidaunorubicin hydrochloride than solvent B.

IPC Classes  ?

• C07D 315/00 - Heterocyclic compounds containing rings having one oxygen atom as the only ring hetero atom according to more than one of groups

Goods & Services

(1) Medicines, namely antirheumatics.

Goods & Services

Pharmaceutical preparations, medicines, chemical preparations for medical purposes, plasters, surgical dressing; disinfectants.

Goods & Services

Pharmaceutical preparations, Medicines, Chemicals for medical use, Plasters, Materials for dressings; Disinfectants.

Goods & Services

Pharmaceutical preparations.

Goods & Services

Pharmaceutical preparations.

Goods & Services

Pharmaceutical preparations.

Goods & Services

Contract manufacturing of pharmaceutical preparations, for others.

Goods & Services

Medicines.

Goods & Services

Pharmaceutical products.

Goods & Services

Medicines, namely antirheumatics.

Goods & Services

Medicines, namely antirheumatics.

Abstract

The invention relates to methotrexate derivatives which contain a protein-binding group and can be enzymatically split in the body such that the active substance or a low-molecular active substance derivative is released. Also disclosed is a method for producing methotrexate derivatives, the use thereof, and medicaments comprising methotrexate derivatives.

IPC Classes  ?

• C07K 5/10 - Tetrapeptides
• C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
• A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

Abstract

The invention relates to concentrated methotrexate solutions containing an active substance for the production of a parenterally administered medicament for the treatment of inflammatory autoimmune diseases. The methotrexate is added to a pharmaceutically compatible solvent, in a concentration of more than 25mg/ml. The invention also relates to a ready-made syringe, a carpule containing such a pharmaceutical solution formulation, and a pen injector comprising such a carpule and/or a ready-made syringe.

IPC Classes  ?

• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• A61P 37/00 - Drugs for immunological or allergic disorders
• A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61P 11/06 - Antiasthmatics
• A61P 17/06 - Antipsoriatics
• A61P 19/00 - Drugs for skeletal disorders
• A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Goods & Services

(1) Pharmaceutical preparations for treating cancer and autoimmune diseases.

Goods & Services

Pharmaceuticals.

Goods & Services

Pharmaceutical products.

Goods & Services

(1) Pharmaceutical and veterinary preparations for treating cancers and autoimmune diseases; preparations for detecting cancers and autoimmune diseases; food for babies; material for stopping teeth, dental wax; preparations for destroying vermin; fungicides, herbicides.

Goods & Services

Pharmaceutical products.

Goods & Services

Pharmaceutical products.

Goods & Services

Pharmaceutical preparations.

Goods & Services

Pharmaceutical products.

Goods & Services

Pharmaceutical products.

Goods & Services

Perfumery, essential oils, cosmetics, hair lotions; soaps; dentifrices. Pharmaceutical and veterinary preparations; sanitary preparations for medical purposes; dietetic substances adapted for medical use, food for babies; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides. Surgical, medical, dental and veterinary apparatus and instruments, artificial limbs, eyes and teeth; orthopedic articles; suture materials.

Goods & Services

Pharmaceutical preparations, namely pharmaceutical preparations for the treatment of cancer or associated diseases and/or side effects of cancer treatment; excluding pharmaceutical preparations for the treatment of migraine.