Abstract

Provided is use of p55γ gene and/or p55γ protein as a target in maintaining cardiac iron homeostasis and treating a related disease, which belongs to the technical field of biomedicine. In the present disclosure, a p55γ transgenic mice model and an ischemia/reperfusion (I/R) injury model in vivo and in vitro are used, and it is proposed that overexpression of p55γ alleviates I/R injury induced cardiac ferroptosis, thereby protecting cardiac function. Moreover, it is found that the overexpression of p55γ leads to downregulation of transferrin receptor 1 (Tfr1) by downregulating iron-regulatory protein 2 (IRP2), thereby maintaining the cardiac iron homeostasis to resist myocardial I/R injuries. This demonstrates a potential of the p55γ gene and/or the p55γ protein as a key regulator of I/R injury induced cardiomyocyte death, thereby providing new targets for maintaining the cardiac iron homeostasis and developing novel therapeutic approaches for related diseases.

IPC Classes  ?

• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• A61K 31/445 - Non-condensed piperidines, e.g. piperocaine
• A61K 38/00 - Medicinal preparations containing peptides
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61P 9/00 - Drugs for disorders of the cardiovascular system
• C12N 15/86 - Viral vectors
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

Provided is a use of Staphylococcus lentus with an accession number of GDMCC 1.247 in preparation of a composition for preventing and treating insulin resistance or type 2 diabetes. This strain can significantly reduce the weight gain induced by a high-fat diet (HFD), improve the glucose tolerance, promote the insulin secretion, improve the insulin resistance, and significantly improve the immunity and inflammation.

IPC Classes  ?

• A61K 35/741 - Probiotics
• C12N 1/20 - BacteriaCulture media therefor
• C12R 1/44 - Staphylococcus

Abstract

Use of a p55gamma protein or an encoding gene thereof as a target in the preparation of a drug for preventing and/or treating vascular calcification is provided, belonging to the technical field of vascular calcification prevention and treatment. The use of the p55gamma protein or the encoding gene thereof as the target in the preparation of the drug for preventing and/or treating the vascular calcification is proposed for the first time, and the p55gamma protein affects the vascular calcification by regulating phosphorylation of Yes-associated protein (YAP). It is proposed for the first time that the vascular calcification can be prevented and/or treated by overexpressing p55gamma gene or increasing the activity of the p55gamma protein.

IPC Classes  ?

• A61K 38/45 - Transferases (2)
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
• C12N 15/86 - Viral vectors

Abstract

A biomarker for predicting drug resistance of a BTK inhibitor and an application thereof are provided in the present disclosure, relating to the technical field of biomedicine. The biomarker is SMPD1 or SPHK1; the drug resistance of BTK inhibitor refers to the drug resistance of diffuse large B cell lymphom cells to the BTK inhibitor. This biomarker is used to predict sensitivity of diffuse large B cell lymphom cells to the BTK inhibitors.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
• A61K 31/713 - Double-stranded nucleic acids or oligonucleotides

Abstract

Disclosed are a hearing state prediction apparatus and method based on a diffusion tensor image, including: obtaining a diffusion tensor image to be processed, wherein the diffusion tensor image comprises a diffusion-weighted image; generating a diffusion index image based on the diffusion-weighted image; determining a white matter microstructural feature corresponding to the diffusion tensor image, and determining a hearing state corresponding to the diffusion tensor image according to a mapping relationship between the white matter microstructural feature and the hearing state. The apparatus may generate the diffusion index image through the diffusion-weighted image included in the diffusion tensor image, and then the white matter microstructural feature is determined based on the diffusion index image, so that the white matter microstructural feature can be identified more accurately, and the accuracy of a hearing state evaluation result is improved. Meanwhile, the relation between hearing disorder and brain microstructure change is disclosed.

IPC Classes  ?

• G06T 7/00 - Image analysis
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• A61B 5/12 - Audiometering
• G06T 7/11 - Region-based segmentation
• G06T 7/50 - Depth or shape recovery
• G06V 10/44 - Local feature extraction by analysis of parts of the pattern, e.g. by detecting edges, contours, loops, corners, strokes or intersectionsConnectivity analysis, e.g. of connected components

Abstract

+Treg cells.

IPC Classes  ?

• A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 35/00 - Antineoplastic agents

Abstract

Disclosed is use of baicalin in preparing a medicament for treating a tumor unresponsive/hyperprogressive to an immune checkpoint inhibitor, the tumor being unresponsive/hyperprogressive to the immune checkpoint inhibitor due to excessive Foxp3+Treg cells. The targeted tumor is one of melanoma, non-small cell lung cancer, renal cell carcinoma, liver cancer, colorectal cancer, urothelial bladder cancer, and pancreatic cancer, and the immune checkpoint inhibitor used comprises one of or a mixture of two or more of a PD-1 inhibitor, a PD-L1 inhibitor, and a CTLA-4 inhibitor. The synergy of the baicalin and the immune checkpoint inhibitor inhibits the number of the Foxp3+Treg cells in tumors, and exerts an anti-tumor sensitization effect, such that various bearing tumors that are unresponsive/hyperprogressive to the immune checkpoint inhibitor due to the excessive Foxp3+ Treg cells can be effectively treated; moreover, obvious adverse reactions are not observed, indicating good safety and wide application prospects.

IPC Classes  ?

• A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
• A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
• A61P 35/00 - Antineoplastic agents

Abstract

Provided is use of Staphylococcus lentus with an accession number of GDMCC 1.247 in preparing a composition for preventing or treating symptoms of insulin resistance or type 2 diabetes. The strain can significantly reduce the weight gain induced by a high-fat diet, improve glucose tolerance, promote insulin secretion, and improve insulin resistance, and can significantly improve immunity and ameliorate inflammation.

IPC Classes  ?

• A61K 35/74 - Bacteria
• A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
• C12N 1/20 - BacteriaCulture media therefor
• A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
• A61P 5/50 - Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
• C12R 1/44 - Staphylococcus

Abstract

An integrated biomarker system for evaluating a risk of impaired fasting glucose (IFG) and type 2 diabetes mellitus (T2DM) for the first time is disclosed. The integrated biomarker system includes quantitative determination results of L-glutamine, L-valine, L-leucine, L-lysine, L-proline, L-phenylalanine, L-arginine, L-glutamic acid, L-isoleucine, L-methionine, L-carnitine, acetyl-L-carnitine, lysophosphatidyl choline (LPC (P-16:0)), LPC (17:0), LPC (14:0) and propionyl-L-carnitine in a sample. The integrated biomarker system for IFG and T2DM of subject serum sample contains a correlative biomarker group on a biological network path to reflect the overall metabolic characteristics information of IFG and T2DM and to avoid that characteristic information of a disease cannot be reflected integrally and completely due to single or separate analysis of a biomarker.

IPC Classes  ?

• G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• G06N 3/08 - Learning methods

Abstract

A method for evaluating adverse reaction of sesquiterpenoids in zedoary turmeric oil is performed successively according to the following steps: (1) preparing a hemoglobin (Hb) solution and a to-be-determined solution; (2) taking Hb solutions with a same volume and respectively adding the same volume of the to-be-determined solution or normal saline thereto, mixing well and standing; (3) determining absorbance with a microplate reader, and comparing the absorbance of a to-be-determined solution group with the absorbance of a normal saline group to obtain a value r; wherein if r>1.5, then the result indicates that the concentration of the to-be-determined solution has a risk of causing dyspnea; wherein, A method for evaluating adverse reaction of sesquiterpenoids in zedoary turmeric oil is performed successively according to the following steps: (1) preparing a hemoglobin (Hb) solution and a to-be-determined solution; (2) taking Hb solutions with a same volume and respectively adding the same volume of the to-be-determined solution or normal saline thereto, mixing well and standing; (3) determining absorbance with a microplate reader, and comparing the absorbance of a to-be-determined solution group with the absorbance of a normal saline group to obtain a value r; wherein if r>1.5, then the result indicates that the concentration of the to-be-determined solution has a risk of causing dyspnea; wherein, r = OD OD Hb ; A method for evaluating adverse reaction of sesquiterpenoids in zedoary turmeric oil is performed successively according to the following steps: (1) preparing a hemoglobin (Hb) solution and a to-be-determined solution; (2) taking Hb solutions with a same volume and respectively adding the same volume of the to-be-determined solution or normal saline thereto, mixing well and standing; (3) determining absorbance with a microplate reader, and comparing the absorbance of a to-be-determined solution group with the absorbance of a normal saline group to obtain a value r; wherein if r>1.5, then the result indicates that the concentration of the to-be-determined solution has a risk of causing dyspnea; wherein, r = OD OD Hb ; in the formula, OD is an absorbance at 280 nm wavelength of the to-be-determined solution after interacting with Hb; ODHb, is an absorbance at 280 nm wavelength of a blank control of normal saline after interacting with Hb.

IPC Classes  ?

• G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
• G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
• G01N 33/72 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving blood pigments, e.g. hemoglobin, bilirubin

Abstract

The present application discloses a cerebral perfusion state classification apparatus and method, a device, and a storage medium. The method includes: acquiring, by a transceiving module, cervical blood flow data from an ultrasound data collecting device; determining, by a processor, cerebral perfusion data corresponding to the cervical blood flow data based on the cervical blood flow data and a mapping relationship between the cervical blood flow data and the cerebral perfusion data, and classifying cerebral perfusion states of a plurality of brain regions based on blood perfusion characteristics of the plurality of brain regions in the cerebral perfusion data.

IPC Classes  ?

• A61B 8/08 - Clinical applications
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/026 - Measuring blood flow
• A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• A61B 8/06 - Measuring blood flow
• G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
• G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

Abstract

The present disclosure discloses a cerebral perfusion state classification apparatus, method and device, and a model training apparatus. In the apparatus, a transceiver module is used for receiving physiological feature data from different data collection devices; and a processor is used for extracting physiological features from the physiological feature data; inputting the physiological features into a random forest model to cause a plurality of decision-making trees in the random forest model to predict a cerebral perfusion state type corresponding to the physiological features; and classifying a cerebral perfusion state based on the cerebral perfusion state type corresponding to the physiological features.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G06N 20/20 - Ensemble learning

Abstract

An elastography method and apparatus, an electronic device, and a storage medium. The method comprises: applying vibrational excitation to a tissue under test and performing ultrasonic detection to obtain an ultrasonic echo signal (S101); generating an ultrasonic detection image (32) and an elasticity detection image according to the ultrasonic echo signal, wherein the elasticity detection image is used for characterizing tissue elasticity detection information and the signal quality of an ultrasonic detection signal at a corresponding moment (S102); and according to the positional relationship between a test area corresponding to the ultrasonic detection image (32) and a test area corresponding to the elasticity detection image, superimposing and displaying the ultrasonic detection image (32) and the elasticity detection image (S103). After the ultrasonic detection image (32) is generated, the elasticity detection image is superimposed and displayed on the ultrasonic detection image (32), and the imaging quality of the ultrasonic detection image (32) is characterized by the elasticity detection image, so that an operator can quickly control the quality of a detection result, eliminating the influence caused by a poor test position and respiration of a testee, etc., the ultrasonic imaging quality is improved, and the accuracy of detection results is improved.

IPC Classes  ?

• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves

Abstract

HbHbHb is an absorbance value at a wavelength of 280 nm after the normal saline reacts with Hb (as a blank control). The present method provides an early warning for safe medication of sesquiterpenoids in curcuma zedoaria oil.

IPC Classes  ?

• G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
• G01N 21/33 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light

Abstract

Disclosed is a method for assessing the risk of impaired fasting glucose (IFG) and type 2 diabetes mellitus (T2DM) by means of using an integrated biomarker, which comprises obtaining the quantitative determination results of L-glutamine, L-valine, L-leucine, L-lysine, L-proline, L-phenylalanine, L-arginine, L-glutamic acid, L-isoleucine, L-methionine, L-carnitine, acetyl L-carnitine, lysophosphatidylcholine (LPC (P-16:0)), LPC (17:0), LPC (14:0) and propionyl L-carnitine in a sample. The established IFG andT2DM subject serum sample integrated biomarker comprises a biomarker group on a mutually associated bionetwork path, reflects the overall metabolic characteristic information of the IFG and the T2DM, and avoids the situation of the biomarker being analyzed singly or separately and thus lacks characteristic information for overall and comprehensive reflection of diseases.

IPC Classes  ?

• G01N 30/88 - Integrated analysis systems specially adapted therefor, not covered by a single one of groups
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

A stent (100) and a placement system (10). The stent (100) has a proximal end and a distal end opposite to each other, and in a direction from the distal end to the proximal end, the stent comprises a first large-diameter section (111), a first connection section (112), a middle section (120), a second connection section (131), and a second large-diameter section (132) which are connected in sequence. In the direction from the distal end to the proximal end, the outer diameter of the first connection section (112) is gradually reduced. Therefore, when the stent (100) is radially compressed to install the stent (100) into a placement device (200), along the axis of the first connection section (112), the middle section (120), the first connection section (112), and the first large-diameter section (111) are located at different axial positions, and thus, the thickness of the first connection section (112) after compression is smaller. Therefore, it is beneficial to reducing the radial pressing force between the first connection section and the displacement device (200) during installation, thereby reducing the friction force between the stent (100) and the placement device (200), and allowing stents having larger sizes to be installed without increasing the inner diameter of the placement device (200).

IPC Classes  ?

• A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
• A61F 2/04 - Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts

Abstract

An endoscope end cap, including a sleeve member, protrusion elements, and a movable sleeve. The sleeve member is connected to the front end of an endoscope, the sleeve member, the protrusion elements, and the movable sleeve are connected in sequence, and the movable sleeve can move freely on the outer surface of the endoscope. When the endoscope is inserted for examination, the end cap is easy to enter and does not scratch the digestive tract since the end cap has a cylinder-like structure which is smooth and has no angularity; when the endoscope is being withdrawn, the movable sleeve moves distally and abuts against the sleeve member, so as to support the protrusion elements to enable the protrusion elements to dilate the inner wall of the intestine, improving the quality of single endoscope examination, and reducing discomfort of a patient, operation risk, and operation time.

IPC Classes  ?

• A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
• A61B 1/32 - Devices for opening or enlarging the visual field, e.g. of a tube of the body
• A61B 1/31 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the rectum, e.g. proctoscopes, sigmoidoscopes

Abstract

A traction apparatus, comprising a clip portion (2) and a traction portion (1), the traction portion containing a closed traction structure (11); the closed traction structure being made from an elastic material; the clip portion comprising a main clip body (23, 25) and a clip arm (24, 26); the main clip body being capable of passing through a biopsy channel (4) of an endoscope (3), the clip arm being capable of clip the closed traction structure. Also disclosed is a traction ring used for the traction apparatus, the traction ring being a single closed traction structure or being formed by connecting several closed traction structures, the traction ring being made from an elastic material.

IPC Classes  ?

• A61B 17/02 - Surgical instruments, devices or methods for holding wounds open, e.g. retractorsTractors
• A61B 17/00 - Surgical instruments, devices or methods

Abstract

Disclosed are a key and keyway attachment denture retention structure and a production method therefore. The production method comprises: 1. collecting three-dimensional space information of a patient's teeth; 2. designing an artificial tooth crown (3) with a key retention structure; 3. integrally producing the artificial tooth crown (3) with a key retention structure; 4. designing a key-way structure (2) matched with the key retention structure; 5. producing the key-way structure (2); and 6. installing the key-way structure (2) in a base (52) of a denture (51) which needs to be fixed with the key-way structure (2). A zirconium dioxide material is integrally formed with adjacent base teeth (6), the precision is high, and the machining process is simplified. A key substrate (4) is provided to prevent the key-way structure (2) from sliding down, and to prevent the denture (51) from sinking.

IPC Classes  ?

• A61C 13/103 - Fastening of artificial teeth to artificial base material, e.g. to palates or to adjacent artificial tooth connected to base material by additional connecting member, e.g. knob or bar
• A61C 13/10 - Fastening of artificial teeth to artificial base material, e.g. to palates or to adjacent artificial tooth
• A61C 13/00 - Dental prosthesesMaking same

Abstract

A traction apparatus, comprising a clamping portion (2) and a traction portion (1), the traction portion containing a closed traction structure (11), the closed traction structure being made from an elastic material, the clamping portion comprising clamping main bodies (23, 25) and clamping arms (24, 26), the clamping main bodies being capable of passing through a biopsy channel (4) of an endoscope (3), the clamping arms being capable of clamping the closed traction structure. Also disclosed is a traction ring for the traction apparatus, the traction ring being a single closed traction structure or being formed by connecting several closed traction structures, the traction ring being made from an elastic material.

IPC Classes  ?

• A61B 17/02 - Surgical instruments, devices or methods for holding wounds open, e.g. retractorsTractors

Abstract

An endoscope end cap, comprising a sleeve member (1, 21, 31), protrusion elements (2, 22, 32), and a movable sleeve (3, 23, 33). The sleeve member (1, 21, 31) is connected to the front end of an endoscope, the sleeve member (1, 21, 31), the protrusion elements (2, 22, 32), and the movable sleeve (3, 23, 33) are connected in sequence, and the movable sleeve (3, 23, 33) can move freely on the outer surface of the endoscope. When the endoscope is inserted for examination, the end cap (101, 201, 301) is easy to enter and does not scratch the digestive tract since the end cap has a cylinder-like structure which is smooth and has no angularity; when the endoscope is being withdrawn, the movable sleeve (3, 23, 33) moves distally and abuts against the sleeve member (1, 21, 31), so as to support the protrusion elements (2, 22, 32) to enable the protrusion elements to dilate the inner wall of the intestine, improving the quality of single endoscope examination, and reducing discomfort of a patient, operation risk, and operation time.

IPC Classes  ?

• A61B 1/31 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the rectum, e.g. proctoscopes, sigmoidoscopes
• A61B 1/32 - Devices for opening or enlarging the visual field, e.g. of a tube of the body

Abstract

This disclosure provides kits and methods for determining whether a subject is suffering from a liver disease, and/or whether the subject will be a responsive to a therapy for a liver disease. The disclosed methods comprise determining the miR profile of exosomes isolated from a body fluid of the subject.

IPC Classes  ?

• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Abstract

The invention provides a method and system for health condition analysis based on an elasticity detection device. The method includes: sending, by a client, a health condition analysis request to a cloud server, where the health condition analysis request includes individual attribute identification information of a querier; acquiring, by the cloud server, to-be-analyzed data corresponding to the health condition analysis request from a cloud database storing displacement data of each querier, and conducting data analysis on the to-be-analyzed data to obtain health condition information of the querier; and receiving, by the client, the health condition information of the querier sent by the cloud server. Therefore, by virtue of mass displacement data of mass queriers stored in the cloud server, the querier can conveniently learn his/her health condition in time through the client.

IPC Classes  ?

• G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
• G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
• G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• A61B 8/08 - Clinical applications

Abstract

This disclosure provides kits and methods for determining whether a subject is suffering from a liver disease, and/or whether the subject will be a responsive to a therapy for a liver disease. The disclosed methods comprise determining the miR profile of exosomes isolated from a body fluid of the subject.

IPC Classes  ?

• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids

Abstract

The present invention provides a method and system for health condition analysis on the basis of an elasticity detection device. The method comprises: a client sends a health condition analysis request to a cloud server, wherein the health condition analysis request comprises individual attribute identification information of a querier; the cloud server acquires data to be analyzed corresponding to the health condition analysis request from a cloud database storing displacement data of each querier, and analyzes the data to be analyzed to obtain health condition information of the querier; and the client receives the health condition information of the querier sent by the cloud server. Therefore, by virtue of mass displacement data of mass queriers stored in the cloud server, the querier can conveniently learn the his/her health condition in time through the client.

IPC Classes  ?

• G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)