The present invention refers to a crystalline form of cabozantinib L-tartrate designated as Form A and a process for its preparation, a pharmaceutical composition comprising it, and its use for the the treatment of patients with progressive, metastatic medullary thyroid cancer (MTC) and for the treatment of patients with advanced renal cell carcinoma (RCC) who have received prior antiangiogenic therapy treatment of cancer.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Dietetic substances suitable for medical and veterinary use;
dietary supplements for humans and animals, food (nutrition)
supplements; medical preparations for slimming purposes;
dietary supplements for human beings and animals; extracts
of medicinal plants and herbal drinks for medicinal
purposes; hygiene products: pads, tampons, medical patches,
dressings, paper and textile diapers for children, adults
and pets; deodorants and odor neutralizing preparations,
except for humans and animals; medicines for human and
animal health, chemical products for medical and veterinary
purposes, chemical radioactive substances for medical and
veterinary purposes, cosmetics containing medicines;
products for dentistry (excluding instruments/devices):
dental filling materials, dental impression materials,
denture and artificial tooth bonding and repair materials;
substances that destroy harmful insects, harmful plants,
harmful fungi and rodents; disinfectants, antiseptics (germ
killers), medical detergents, medicated soaps, disinfecting
soaps, antibacterial hand lotions.
3.
NOVEL POLYMORPH OF RUXOLITINIB HEMIFUMARATE AND METHOD OF PREPARATION
The present invention relates to a new crystalline polymorphic form of ruxolitinib hemifumarate, namely Form III, and methods for its preparation. The new crystalline polymorph Form III of ruxolitinib hemifumarate is characterized by an XRPD pattern having characteristic peaks (2-theta ± 0.2º) at 13.7, 19.3, 21.5 and 22.7. The present invention also provides pharmaceutical compositions comprising Form III of ruxolitinib hemifumarate, and medical use of Form III.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations for medical
purposes; chemical preparations for medical purposes;
dietary supplements, including those adapted for medical
purposes; nutritional supplements; dietary supplements for
slimming purposes; food for babies; herbs and herbal
beverages adapted for medicinal purposes; dental
preparations and articles: teeth filling material, dental
impression material, dental adhesives, and material for
repairing teeth; sanitary preparations for medical use;
hygienic pads; hygienic tampons; plasters; materials for
dressings; diapers, including those made of paper and
textiles; preparations for destroying vermin; fungicides,
herbicides; deodorants, other than for human beings or for
animals; air deodorising preparations; disinfectants;
antiseptics; detergents for medical purposes.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations for medical
purposes; chemical preparations for medical and veterinary
purposes, chemical reagents for pharmaceutical and
veterinary purposes; dietary supplements for pharmaceutical
and veterinary purposes; dietary supplements; nutritional
supplements; medical preparations for slimming purposes;
food for babies; herbs and herbal beverages adapted for
medicinal purposes; dental preparations and articles: teeth
filling material, dental impression material, dental
adhesives and material for repairing teeth; sanitary
preparations for medical use; hygienic pads; hygienic
tampons; plasters; materials for dressings; diapers,
including those made of paper and textiles; preparations for
destroying vermin; fungicides, herbicides; deodorants, other
than for human beings or for animals; air deodorising
preparations; disinfectants; antiseptics; detergents for
medical purposes.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations for medical
purposes; chemical preparations for medical and veterinary
purposes, chemical reagents for pharmaceutical and
veterinary purposes; medicated cosmetics; dietary
supplements for pharmaceutical and veterinary purposes;
dietary supplements; nutritional supplements; medical
preparations for slimming purposes; food for babies; herbs
and herbal beverages adapted for medicinal purposes; dental
preparations and articles: teeth filling material, dental
impression material, dental adhesives and material for
repairing teeth; sanitary preparations for medical use;
hygienic pads, hygienic tampons; plasters, materials for
dressings, diapers made of paper and textiles for babies,
adults and pets; preparations for destroying vermin;
herbicides, fungicides, preparations for destroying rodents;
deodorants, other than for human beings or for animals; air
purifying preparations; air deodorising preparations;
disinfectants; antiseptics; detergents for medical purposes;
medicated soaps; disinfectant soaps; antibacterial hand
lotions.
7.
NOVEL POLYMORPH OF VISMODEGIB AND METHOD OF PREPARATION
The present invention relates to a new crystalline form of vismodegib, a methanol-solvate of vismodegib, namely Form S, and methods for its preparation. The vismodegib Form S is characterized by an XRPD pattern having characteristic peaks (2theta ± 0.2º) at 7.1, 14.0, 16.7, 19.1, 22.3, 24.6 and 28.0. The present invention also provides interconversion process of vismodegib Form S to crystalline vismodegib Form B, pharmaceutical compositions comprising vismodegib Form S, and medical use of vismodegib Form S.
The present invention relates to a new crystalline polymorphic form of ruxolitinib hemifumarate hemihydrate, namely Form II, and methods for its preparation. The new crystalline polymorph Form II of ruxolitinib hemifumarate hemihydrate is characterized by an XRPD pattern having characteristic peaks (2theta ± 0.2º) at 5.4, 16.9 and 21.4. The present invention also provides pharmaceutical compositions comprising Form II of ruxolitinib hemifumarate hemihydrate, and medical use of Form II.
The present invention relates to a new crystalline polymorphic Form X of vismodegib and its preparation. Preferably, the new crystalline polymorphic Form X of vismodegib is characterized by an XRPD pattern having characteristic peaks at 9.37 ± 0.2, 11.49 ± 0.2, 15.70 ± 0.2, 16.56 ± 0.2, 18.84 ± 0.2, 18.95 ± 0.2 and 23.85 ± 0.2 degree 2-theta. The present invention also provides pharmaceutical compositions comprising Form X of vismodegib, and medical use of Form X of vismodegib.
The present invention relates to a new crystalline polymorph of benserazide hydrochloride. More specifically, the invention relates to novel Form H of benserazide hydrochloride, process for preparing the novel form of benserazide hydrochloride and pharmaceutical formulations comprising the novel form of benserazide hydrochloride.
C07C 243/34 - Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a carbon skeleton further substituted by nitrogen atoms
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations for medical
purposes; chemical preparations for medical and veterinary
purposes, chemical reagents for pharmaceutical and
veterinary purposes; medicated cosmetics; dietary
supplements for pharmaceutical and veterinary purposes;
dietary supplements; nutritional supplements; medical
preparations for slimming purposes; food for babies; herbs
and herbal beverages adapted for medicinal purposes; dental
preparations and articles: teeth filling material, dental
impression material, dental adhesives and material for
repairing teeth; sanitary preparations for medical use;
hygienic pads; hygienic tampons; plasters; materials for
dressings; diapers made of paper and textiles for babies,
adults and pets; preparations for destroying vermin;
herbicides, fungicides, preparations for destroying rodents;
deodorants, other than for human beings or for animals; air
purifying preparations; air deodorising preparations;
disinfectants; antiseptics; detergents for medical purposes;
medicated soaps; disinfectant soaps; antibacterial hand
lotions.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations for medical
purposes; chemical preparations and elements for medical
purposes dietary supplements, including those adapted for
medical purposes; dietary supplements for slimming purposes;
food for babies; herbs and herbal beverages adapted for
medicinal purposes; dental preparations (except
tools/devices); sanitary preparations for medical use,
namely hygienic pads, hygienic tampons, plasters, materials
for dressings; preparations for destroying vermin;
fungicides, herbicides; air deodorising preparations (other
than for personal use); disinfectants; antiseptics;
detergents for medical purposes.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
35 - Advertising and business services
36 - Financial, insurance and real estate services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical and veterinary preparations for medical
purposes; chemical preparations for medical and veterinary
purposes, chemical reagents for pharmaceutical and
veterinary purposes; medicated cosmetics; dental
preparations and articles; teeth filling material, dental
impression material, dental adhesives and material for
repairing teeth; sanitary preparations for medical use;
hygienic pads; hygienic tampons; plasters; materials for
dressings; diapers made of paper and textiles for babies,
adults and pets; preparations for destroying vermin;
herbicides, fungicides, preparations for destroying rodents;
deodorants, other than for human beings or for animals; air
purifying preparations; air deodorising preparations;
disinfectants; antiseptics; detergents for medical purposes;
medicated soaps; disinfectant soaps; antibacterial hand
lotions. Surgical, medical, dental and veterinary apparatus and
instruments; furniture especially made for medical purposes;
artificial limbs and prostheses; medical orthopaedic
articles; corsets for medical purposes, orthopaedic shoes,
elastic bandages and supportive bandages; surgical gowns and
surgical sterile sheets; adult sexual aids; condoms; babies'
bottles; babies' pacifiers; teats; teethers for babies;
bracelets and rings for medical purposes, anti-rheumatism
bracelets; anti-rheumatism rings. Office functions; secretarial services; arranging newspaper
subscriptions for others; compilation of statistics; rental
of office machines; systemization of information into
computer databases; telephone answering for unavailable
subscribers; auctioneering. Insurance services; financial and monetary affairs; real
estate brokers, real estate agencies and real estate
management; customs brokerage services. Scientific and industrial analysis and research services;
engineering; engineering and architectural design services;
testing services for the certification of quality and
standards; computer services, namely, computer programming,
computer virus protection services, computer system design,
creating, maintaining and updating websites for others,
computer software design, updating and rental of computer
software, providing search engines for the Internet, hosting
websites, consultancy in the design and development of
computer hardware, rental of computer hardware;
authenticating works of art.
The invention discloses novel pharmaceutically acceptable salts of eltrombopag and process for preparing the same. The invention also relates to solid state forms of eltrombopag sesquiethanolamine and processes for the preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
C07D 231/10 - Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
The present invention relates to a new process for the preparation of a key intermediate compound and its use in a synthetic process for the preparation of pazopanib hydrochloride. The method has advantages of a simple operation, high yield and low costs. The present invention also relates to a novel polymorph of pazopanib hydrochloride.
C07D 403/02 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings
C07D 403/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
16.
AN IMPROVED PROCESS FOR PREPARATION OF SCOPINE HYDROBROMIDE
The present invention relates to an efficient and industrially advantageous process for the preparation of scopine free base or salts. Said compounds are important intermediates in the synthesis of tiotropium and pharmaceutically acceptable salts thereof. The method provided for preparing scopine free base or its salts has the advantages of a simple operation, high yield and low costs.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceuticals, medical and veterinary preparations, namely, for treating malignant tumors, cancer and blood disorders, urological diseases and disorders, dermatological diseases and disorders namely skin and bacterial skin infections and fungal skin infections, genitourinary system disorders namely urological diseases, sexually transmitted diseases, inflammatory pelvic diseases and sexual hormone disorders, cardiovascular diseases, musculoskeletal diseases, central and peripheral nervous system disorders, gastrointestinal diseases, metabolic diseases and disorders namely diabetes, gout, arthritis and anemia, systemic endocrine diseases namely growth and thyroid disorders, respiratory system disorders and diseases, namely asthma and COPD, ophthalmological diseases and disorders, namely glaucoma, dry eye disease, allergy, other sensory organs disorders; sanitary preparations for medical purposes, namely, medicated cleansers for skin and wounds; dietetic food and substances adapted for medical or veterinary use, namely, for the prevention and treatment of iron deficiency and anaemia in humans and in animals, food for babies; dietary supplements for human beings and animals, namely, for general health and well-being; plasters as materials for dressings; material for stopping teeth, dental wax; all-purpose disinfectants; preparations for destroying vermin; fungicides; herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceuticals, medical and veterinary preparations, namely, for treating malignant tumors, cancer and blood disorders, urological diseases and disorders, dermatological diseases and disorders namely skin and bacterial skin infections and fungal skin infections, genitourinary system disorders namely urological diseases, sexually transmitted diseases, inflammatory pelvic diseases and sexual hormone disorders, cardiovascular diseases, musculoskeletal diseases, central and peripheral nervous system disorders, gastrointestinal diseases, metabolic diseases and disorders namely diabetes, gout, arthritis and anemia, systemic endocrine diseases namely growth and thyroid disorders, respiratory system disorders and diseases, namely asthma and COPD, ophthalmological diseases and disorders, namely glaucoma, dry eye disease, allergy, other sensory organs disorders; sanitary preparations for medical purposes, namely, medicated cleansers for skin and wounds; dietetic food and substances adapted for medical or veterinary use, namely, for the prevention and treatment of iron deficiency and anaemia in humans and in animals, food for babies; dietary supplements for human beings and animals, namely, for general health and well-being; plasters as materials for dressings; material for stopping teeth, dental wax; all-purpose disinfectants; preparations for destroying vermin; fungicides, herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations;
sanitary preparations for medical purposes; dietetic food
and substances adapted for medical or veterinary use, food
for babies; dietary supplements for human beings and
animals; plasters, material for stopping teeth, dental wax;
disinfectants; preparations for destroying vermin;
fungicides, herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for use in treating by inhibiting the growth of tumors, as antiparasitics, and for treatment of the nervous systems, orthopedic and musculoskeletal disease, respiratory disease, genital and urologic disease, endocrinology disease, cardiovascular disease, dermatological disease, metabolic disease, gastrointestinal disease, hormonal diseases, ophthalmological disease, cancer and diseases of the blood, and for use in treating immune function, psychiatric disorders, fatigue, and sexual disfunction; veterinary preparations for use in treating by inhibiting the growth of tumors, as antiparasitics, and for treatment of the nervous systems, orthopedic and musculoskeletal disease, respiratory disease, genital and urologic disease, endocrinology disease, cardiovascular disease, dermatological disease, metabolic disease, gastrointestinal disease, hormonal diseases, ophthalmological disease, cancer and diseases of the blood, and for use in treating immune function, psychiatric disorders, fatigue, and sexual disfunction; sanitary preparations for medical purposes; dietetic foods, namely, food supplements and dietary supplements adapted for medical use; dietetic sugar for medical use; food for babies; dietary supplements for humans and animals; medical plasters; material for stopping teeth, dental wax; all-purpose disinfectants; preparations for destroying vermin; fungicides, herbicides
21.
A PROCESS FOR PREPARATION OF 1H-PYRAZOLO[3,4-D] PYRIMIDINE DERIVATIVES
The present invention relates to an efficient and industrially advantageous process for the preparation of 1H-pyrazolo[3,4-d] pyrimidine derivatives. In particular the present invention provides a process for the preparation of 4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4- d]pyrimidine and tert-butyl (R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4- d]pyrimidin-1-yl)piperidine-1-carboxylate. Said compounds are important intermediates in the synthesis of ibrutinib. The method provided for preparing intermediates of ibrutinib has the advantages of a simple operation, high yield and low costs.
The object of the present invention is to provide a pharmaceutical composition comprising solid dispersion of selinexor, having enhanced bioavailability and improved dissolution properties. In accordance with the invention, solid dispersion of selinexor is produced by hot melt extrusion method.
A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings
C07D 403/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations;
sanitary preparations for medical purposes; dietetic food
and substances adapted for medical or veterinary use, food
for babies; dietary supplements for human beings and
animals; plasters, materials for dressings; material for
stopping teeth, dental wax; disinfectants; preparations for
destroying vermin; fungicides, herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations;
sanitary preparations for medical purposes; dietetic food
and substances adapted for medical or veterinary use, food
for babies; dietary supplements for human beings and
animals; plasters, materials for dressings; material for
stopping teeth, dental wax; disinfectants; preparations for
destroying vermin; fungicides; herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for use in treating by inhibiting the growth of tumors, as antiparasitics, and for treatment of the nervous systems, orthopedic and musculoskeletal disease, respiratory disease, genital and urologic disease, endocrinology disease, cardiovascular disease, dermatological disease, metabolic disease, gastrointestinal disease, hormonal diseases, ophthalmological disease, cancer and diseases of the blood, and for use in treating immune function, psychiatric disorders, fatigue, and sexual disfunction; veterinary preparations for use in treating by inhibiting the growth of tumors, as antiparasitics, and for treatment of the nervous systems, orthopedic and musculoskeletal disease, respiratory disease, genital and urologic disease, endocrinology disease, cardiovascular disease, dermatological disease, metabolic disease, gastrointestinal disease, hormonal diseases, ophthalmological disease, cancer and diseases of the blood, and for use in treating immune function, psychiatric disorders, fatigue, and sexual disfunction; sanitary preparations for medical purposes; dietetic foods namely, food supplements and dietary supplements adapted for medical use; dietetic sugar for medical use; food for babies; dietary supplements for humans and animals; medical plasters, materials for dressings; material for stopping teeth, dental wax; all purpose disinfectants; preparations for destroying vermin; fungicides, herbicides
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for use in treating by inhibiting the growth of tumors, as antiparasitics, and for treatment of the nervous systems, orthopedic and musculoskeletal disease, respiratory disease, genital and urologic disease, endocrinology disease, cardiovascular disease, dermatological disease, metabolic disease, gastrointestinal disease, hormonal diseases, ophthalmological disease, cancer and diseases of the blood, and for use in treating immune function, psychiatric disorders, fatigue, and sexual disfunction; veterinary preparations for use in treating by inhibiting the growth of tumors, as antiparasitics, and for treatment of the nervous systems, orthopedic and musculoskeletal disease, respiratory disease, genital and urologic disease, endocrinology disease, cardiovascular disease, dermatological disease, metabolic disease, gastrointestinal disease, hormonal diseases, ophthalmological disease, cancer and diseases of the blood, and for use in treating immune function, psychiatric disorders, fatigue, and sexual disfunction; sanitary preparations for medical purposes; dietetic foods namely, food supplements and dietary supplements adapted for medical use; dietetic sugar for medical use; food for babies; dietary supplements for humans and animals; medical plasters, materials for dressings; material for stopping teeth, dental wax; all purpose disinfectants; preparations for destroying vermin; fungicides, herbicides
27.
A PROCESS FOR PREPARATION OF 5-(2-(SUBSTITUTED-AMINO)-1-HYDROXYETHYL)-8-(SUBSTITUTED-OXY) QUINOLIN-2(1H)-ONE
The present invention is related to a novel process for preparing compounds, which are useful intermediates to prepare Indacaterol salts. The invention process presents high yields in all steps of the synthesis. The present invention also avoids the use of the epoxide compound known in the art and the by products associated therewith. The novel process is economically favourable due to the process comprising easily accessible reagents.
New crystalline monohydrate forms of Benidipine HCl, Form C, Form D, Form E, Form F, Form G, Form H and Form I, compositions comprising these crystalline solid forms, and processes for preparing these crystalline solid forms are described herein.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Dietetic food and substances adapted for medical use, food
for babies, medical herbs and herbal drinks, dental products
(excluding devices), sanitary preparations for personal
hygiene, other than toiletries; preparations for destroying
vermin; fungicides, herbicides, deodorants other than for
human beings, disinfectants, antiseptics, detergents for
medical purposes.
This invention relates to ricobendazole formulations used to control parasite species in animals and to treat the infections caused by such parasites and their methods of manufacture.
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; dietetic food and
substances adapted for medical or veterinary use, food for
babies; dietary supplements for humans and animals;
plasters, materials for dressings; material for stopping
teeth, dental wax; disinfectants; preparations for
destroying vermin; fungicides, herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; dietetic food and
substances adapted for medical or veterinary use, food for
babies; dietary supplements for humans and animals;
plasters, materials for dressings; material for stopping
teeth, dental wax; disinfectants; preparations for
destroying vermin; fungicides, herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; dietetic food and
substances adapted for medical or veterinary use, food for
babies; dietary supplements for humans and animals;
plasters, materials for dressings; material for stopping
teeth, dental wax; disinfectants; preparations for
destroying vermin; fungicides, herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; dietetic food and
substances adapted for medical or veterinary use, food for
babies; medical dietary supplements for humans and animals;
plasters, materials for dressings; material for stopping
teeth, dental wax; disinfectants; preparations for
destroying vermin; fungicides, herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; dietetic food and
substances adapted for medical or veterinary use, food for
babies; dietary supplements for humans and animals;
plasters, materials for dressings; material for stopping
teeth, dental wax; disinfectants; preparations for
destroying vermin; fungicides, herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; dietetic food and
substances adapted for medical or veterinary use, food for
babies; dietary supplements for humans and animals;
plasters, materials for dressings; material for stopping
teeth, dental wax; disinfectants; preparations for
destroying vermin; fungicides, herbicides.
The present invention is related to easy to use dosage forms of mozavaptan or a pharmaceutically acceptable salt thereof comprising orally disintegrating tablets, effervescent tablets, granules in sachets, dry syrup and manufacturing methods thereof.
This invention is related to single unit formulation of fingolimod or pharmaceutically acceptable salts thereof in combination with nabiximols mostly composed of cannabidiol (CBD) type compound or derivative thereof and tetrahydrocannabinol (THC) type compound or derivative thereof in treatment of multiple sclerosis.
A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
The present invention is related to easy to use dosage forms for low formulations of eprotirome comprising orally disintegrating tablets, effervescent tablets, granules in sachets, dry syrup and manufacturing methods thereof.
This invention relates to an aerosol can sample content extractor apparatus for deternnining of drug content (assay) and water content or moisture content of aerosol formulation from pressurized metered dose inhalers (MDI).The device allows the accurate determination of the amount of drug inside the canister.
The invention relates to single unit dosage pharmaceutical formulations comprising sevelamer or a pharmaceutically acceptable salt thereof and a fat soluble vitamin such as A, D, E, K or their analogues or mixtures thereof as well as methods of manufacturing of monolithic tablet, bilayer tablet, tablet in tablet, in lay tablet, granules in sachet, coated core tablet forms by achieving targeted content uniformity and patient compliance.
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
45.
PARTICLE SIZE DISTRIBUTION OF CETYL MYRISTATE AND/OR CETYL PALMITATE
This invention is related to defining critical particle size distribution of granules and/or powder mixtures of cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate and optimizing process parameters for manufacturing.
This invention is directed to wet granulation methods through isopropyl alcohol, dichloromethane, methanol, acetone or mixtures thereof for manufacturing of cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate.
This invention is related to pharmaceutical combination of betahistine or pharmaceutically acceptable salts thereof and trimetazidine or pharmaceutically acceptable salts thereof.
A61K 31/4402 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
A61K 31/495 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
This invention is related to a preparing method for pharmaceutical and/or dietary supplement suspension formulations of cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate.
A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 9/00 - Medicinal preparations characterised by special physical form
49.
SUSPENSION FORMULATIONS OF CETYL MYRISTATE AND/OR CETYL PALMITATE
This invention is related to pharmaceutical or dietary supplement suspension formulations of cetylated fatty acids, especially cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate.
A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 9/00 - Medicinal preparations characterised by special physical form
50.
FORMULATIONS OF CETYL MYRISTATE AND/OR CETYL PALMITATE PARTICLES
This invention is related to spray drying or melt granulation or dissolving or dispersing treatment of cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate.
A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
51.
CONTROLLED MOISTURE CONTENT OF CETYL MYRISTATE AND/OR CETYL PALMITATE GRANULES OR FORMULATIONS
This invention is directed to drying methods and determining of water content in granules or pharmaceutical/dietary supplement compositions or finished dosage forms of cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate.
A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
52.
CETYL MYRISTATE AND/OR CETYL PALMITATE GRANULES HAVING HIGH BULK DENSITY
This invention is related to a preparation method of cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate by using dry granulation techniques wherein obtained granules having a bulk density equal or greater than 0.30 g/mL.
A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 9/00 - Medicinal preparations characterised by special physical form
This invention is related to bilayer tablet, inlay tablet, tablet in tablet, tablet in capsule, capsule in capsule, separated granulation and kit of combination of cetyl myristate and cetyl palmitate.
A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 9/00 - Medicinal preparations characterised by special physical form
This invention is related to using of anti-adherents in pharmaceutical or dietary supplement formulations of cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate. In this invention, cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate are used as active pharmaceutical ingredients.
This invention is related to coated particles of cetylated fatty acids, especially cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate by using wet granulation techniques.
This invention is related to using of superdisintegrants in pharmaceutical or dietary supplement formulations of cetylated fatty acids, especially cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate.
This invention is related to a sieving method of cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate by using screen wherein screen size is 1 mm to 1.4 mm. This invention is also directed to using of lubricants/glidants in formulations of cetyl myristate or cetyl palmitate or combination of cetyl myristate and cetyl palmitate wherein API's are sieved by screen of 1 mm to 1.4 mm.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations in the form of capsules (for
medicine), suspensions (medicine), suppositories, syrup (for
medical purposes), drops, tablets, pills (for pharmaceutical
purposes).
